title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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The pharmacokinetic aspects of therapy with psychotropic agents. | This contribution is concerned with a critical appraisal of the concept that plasma levels of psychotropic agents govern their pharmacodynamic action. In this regard, there are at least three problems: 1. identification of the chemical course of reaction between the introduced pharmacon and its resultant metabolites in... | 631,968 | [
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Thiolysis of Nim-2,4-dinitrophenyl-histidine peptides with 2-mercaptoethanol. An explannation for the pH optimum. | The thiolysis of Nim-2,4-dinitrophenyl-histidine peptides with 2-mercaptoethanol demonstrates an optimal rate between pH 8.5 and 9.0. Base lability of both reactants and product was investigated as a possible cause for the pH optimum. N-2,4-Dinitrophenylimidazole, a model for Nim-2,4-dinitrophenylhistidine peptides, 2-... | 631,983 | [
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Primary specificity of alakaline mesentericopeptidase. Kinetic parameters for the hydrolysis of alpha-N-acetyl-L-amino acid methyl esters. | The steady-state kinetics of the alkaline mesentericopeptidase-catalysed hydrolysis of esters of the general formula Ac-X-OMe(OEt) has been studied, "X" being an amino acid residue (Ala, Val, Leu, Ile, Phe, Tyr, Trp, Lys). The values of the specificity ratio kcat/Km indicate that the bonds involving the carboxyl group ... | 631,984 | [
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Influence of supplemental dietary fat on the relative proportions of three classes of lipid in the epiphyseal cartilage of dwarf and non-dwarf chicks. | One hundred and forty-four day-old chicks were allotted to six groups in a 2 x 3 factorial design involving two strains (dwarf, dw and non-dwarf, Dw+) and three levels of supplemental dietary fat (none, moderate and high). The birds were killed at four weeks of age. The overall weight gain and the total lipid content, ... | 632,014 | [
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Rapid access airway: surgical device and technique. | A simple, inexpensive, readily assembled device that provides immediate temporary access to the subglottic airway for oxygenation or anesthesia induction has been presented. The device can be used in emergency clinical situations, in difficult anesthesia inductions and in children where it is difficult to introduce an ... | 632,034 | [
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Hepatic resection for isolated tumor-like nodules in the liver. | We have reported two cases of focal nodular hyperplasia of the liver in adults. One case is the first in which the regenerative process that occurred nine months after localized hepatic necrosis was implicated in the development of focal nodular hyperplasia. The other case concerned an idiopathic isolated liver nodule ... | 632,036 | [
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Radiological evaluation of rat colonic tumors. | Colon carcinomata were induced in rats with N-methyl-N-nitro-N-nitrosoguanidine. A magnified double contrast barium enema technique was developed for an in vivo study of tumor growth patterns. Invariably, all small tumors were smoothly outlined and were spherical or ellipsoidal in shape. Irregularity developed only whe... | 632,046 | [
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Infant mortality in SMSAs before Medicaid: test of a causal model. | Path analysis is applied to data on infant mortality, supplies of physicians and hospital beds, and population percentages of blacks and low-income families in 201 standard metropolitan statistical areas (SMSAs) to test the hypothesis that medical resources mediate the effects of racial composition and low income on in... | 632,103 | [
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The light and electron microscopic distribution of acid phosphatase activity in human normal oesophageal epithelium. | Acid phosphatase activity in human normal oesophageal epithelium was studied with light and electron microscopic techniques. The maximum activity was found to be in the prickle and lower functional layers. Electron microscopic examination revealed activity to be localized in GERL, lysosomes and membrane coating granule... | 632,122 | [
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Early response of plasma contents on exposure of working men to heat. | Twelve men block-stepped (35 W) 4 h/day for 12 days and were divided into two similar groups on the basis of Vo2max. All were exposed to 33.8 degrees C dry bulb, 32.7 degrees C wet bulb for 2 h (E1) while working (30% Vo2max). Venous blood was obtained at 10-min intervals during hour 1 and at 20-min intervals during ho... | 632,155 | [
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Bilateral torsion of uterine horns in a nongravid bitch. | Hematometra was diagnosed in a 13-year-old, nulliparous Toy Poodle by fine needle aspiration and radiographic studies, including pneumoperitoneography. Attempted uterine evacuation with simultaneous use of diethylstilbestrol and ergonovine was unsuccessful. Exploratory celiotomy revealed 1,080-degree torsion of the rig... | 632,203 | [
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Electron microscopic and cytochemical observations on the membrane systems of the chicken thrombocyte. | A combined electron microscopic and cytochemical study of the thrombocytes of the mature chicken has demonstrated the existence of two membrane systems, the surface connected system (SCS) and the dense tubular system (DTS). The SCS consists of light tubules and vacuoles which are in continuity with the plasmalemma. A r... | 632,207 | [
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Synthesis and metabolism of 5beta-[11,12-3H]cholestane-3alpha, 7alpha-diol. | 5beta-[11,12-3H]Cholestane-3alpha,7alpha-diol was synthesized as follows. 5beta-Cholestane-3alpha,7alpha,12atriol 3,7-diacetate was treated with phosphorus oxychloride in pyridine solution and then the product, 5beta-cholest-11-ene-3alpha,7alpha-diol diacetate, was hydrogenated in acetic acid solution using platinum ox... | 632,228 | [
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Localization of the alpha-chain cross-link acceptor sites of human fibrin. | The potential cross-link acceptor sites of fibrin were specifically labeled with the fluorescent, substitute cross-link donor monodansyl cadaverine (MDC). Several fluorescent alpha-chain peptides generated from enzymatic and cyanogen bromide (CNBr) cleavage of the labeled fibrin were identified by sodium dodecyl sulfat... | 632,262 | [
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Isolation of vitamin K2(35) from Nocardia restrictus and Corynebacterium simplex. A natural electron acceptor in microbial steroid ring A dehydrogenations. | Isooctane extraction of cells from Nocardia restrictus and Corynebacterium simplex followed by chromatographic separation gave yellow crystals which were identified as vitamin K2(35) by its ultraviolet absorption, nuclear magnetic resonance spectrum, and mass spectrometry. The purified vitamin K2(35) was found to stimu... | 632,275 | [
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Ketogenesis and malonyl coenzyme A content of isolated rat hepatocytes. | We have measured rates of ketogenesis and malonyl-CoA contents of hepatocytes isolated from meal-fed rats under a variety of incubation conditions in order to determine the relationship between the intracellular malonyl-CoA level and the rate of ketogenesis. Evidence obtained from rat liver homogenates suggested that m... | 632,284 | [
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Protein sorption on polymer surfaces measured by fluorescence labels. | Fluorescence labeling can be used in studying protein sorption on various surfaces with a sensitivity of about 10(-8) g/cm2, commensurate with radioactive labeling. Fluorescamine proved to be the most suitable compound for studying protein sorption on hydrophilic gels, because, unlike fluoresceine isothiocyanate and da... | 632,317 | [
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[The place of intrahepatic peripheral anastomoses in neoplastic obstruction of the upper bile duct junction. Report of 20 cases (author's transl)]. | In 32 patients with carcinoma involving the bifurcation of the hepatic ducts 17 intrahepatic cholangiojejunostomies and 3 intrahepatic gastrotomies were performed. The post-operative mortality rate is high (35%), the median survival time is 9 months. These results suggest that resection should by attempted when possibl... | 632,328 | [
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Laboratory and clinical investigation of recovery of Salmonella typhi from blood. | An experimental study was undertaken of isolation of Salmonella typhi from artificially infected whole blood and blood clot prepared either with small numbers of freshly isolated strains or with the S. typhi Ty2 strain. Results showed that 8 ml of whole blood required a minimum of 50 ml of bile salt broth to dilute the... | 632,343 | [
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Rapid plate agglutination procedure for serotyping Pasteurella haemolytica. | A specific, rapid plate agglutination procedure for serotyping Pasteurella haemolytica was performed. The procedure did not require special antigen preparation and yielded essentially the same results as the indirect hemagglutination procedure. | 632,345 | [
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Aerobic bacterial flora of oral and nasal fluids of canines with reference to bacteria associated with bites. | Oral and nasal fluids of 50 dogs were examined to determine the prevalence of aerobic bacteria frequently associated with animal bite wounds. The most frequently isolated microorganisms included: IIj, EF-4, Pasteurella multocida, Staphylococcus aureus, Staphylococcus epidermidis, group D streptococci, Corynebacterium s... | 632,349 | [
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Spectrum of renal tubular damage in renal failure secondary to cirrhosis and fulminant hepatic failure. | Measurements of urinary lysozyme were used to evaluate renal tubular integrity in 34 patients with cirrhosis or fulminant hepatic failure who had developed renal impairment. In 18 of the patients the lysozyme values were normal but in the remaining 16 were increased, supporting previous concepts that renal failure comp... | 632,352 | [
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The case for laboratory aides in district clinical chemistry departments. | A case of need is made out for the general introduction into district clinical chemistry departments of the existing experimental grade of laboratory aide or assistant. Subject to direct supervision by qualified personnel the aide has a useful role to fulfil. Important advantages to staff and patients accrue from the e... | 632,357 | [
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A comparison of four potential agents for reducing necrosis after prolonged coronary occlusion. | In anesthetized closed-chest dogs, four vasodilators were compared after prolonged coronary occlusion induced by catheter wedging in a coronary branch. With treatment given between 1 hour and 2 hours of occlusion, five groups were studied: no treatment, isosorbide dinitrate, nitroprusside, dipyridamole, and methylpredn... | 632,362 | [
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Evaluation of intravenous clonidine in hypertensive emergencies. | Nineteen patients with severe essential hypertension or hypertension due to renal parenchymal disease were treated with intravenous clonidine. In 14 patients the elevated blood pressure was complicated by one or more crises: left ventricular failure in seven patients, encephalopathy in six, and subarachnoid hemorrhage,... | 632,367 | [
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The effect of refeeding after neonatal starvation on Purkinje cell dendritic growth in the rat. | Male rats, undernourished from birth until 30 days by restricting access to the lactating dam, were given ad libitum food supplies unitl 80 days. Body weight, whole brain weight and cerebellar remained significantly lower in these animals than in normally fed controls. Significant deficits in the area of the molecular ... | 632,380 | [
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The reaction of adolescent offenders and nonoffenders to nonverbal emotion displays. | Adolescent male offenders and nonoffenders were compared on two tasks designed to assess reactions to the nonverbal emotion expressions of others. It was found that the offender group was less accurate in labeling another's emotion states but that this difference was apparently a function of verbal intelligence. Furthe... | 632,460 | [
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Hormones: beneficial or dangerous to the aged? | Postmenopausal women lose 75-85 percent of estrogen and progesterone production compared with that in their reproductive years. The marked decrease in estrogen results in changes in the uterus, cervix, vaginal lining, glandular breast tissue, and the rate at which bone loses thickness. Some of these changes result in s... | 632,497 | [
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0.1434573,
0.1325736,
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0.3848655,
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Chronic fracture-subluxation of the proximal interphalangeal joint. | Reported methods of treatment of chronic fracture-subluxations of the proximal interphalangeal joint require wide dissection and prolonged immobilization and often result in limited motion. Open reduction with minimal dissection, immobilization for 11 days to allow soft-tissue healing, and the early institution of acti... | 632,544 | [
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Trials of the rodenticide pyriminil against wild house mice (Mus musculus L.). | Pen field trials were conducted to assess the performance of the acute rodenticide pyriminil against the house mouse (Mus musculus L.). Four types of poison treatment were carried out using penned family groups of warfarin-resistant mice supplied with alternative plain foods. In each treatment pyriminil was included at... | 632,570 | [
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The impact of occupational licensure of clinical laboratory personnel. | This paper develops a model of the economic impact of occupational licensure. The model is then used to estimate the effects of occupational licensure on wages and the division of labor in clinical laboratories and to generate a low-bound estimate of the welfare impact of licensure. Estimates are based on cross-section... | 632,575 | [
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Spontaneous haematoma in the head and neck. | Three cases of spontaneous haematoma in the head and neck are presented. Whereas one case was associated with lingual haemangiomatosis, no source of bleeding could be demonstrated in either a chronic, spontaneous orbital blood-cyst or an acute retropharyngeal haematoma. | 632,660 | [
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Determination of double bond positions of unsaturated fatty acids by a chemical ionization mass spectrometry computer system. | After stereospecific oxidation, trimethylsilylated methyl esters of mono- and diunsaturated fatty acids were analyzed by combined gas-liquid chromatography-chemical ionization mass spectrometry. The positions of original double bonds were deduced from the fragment ions produced by the cleavage of the carbon-carbon bond... | 632,680 | [
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Variability of chimaeras and mosaics. | Aggregation chimaeras and X-inactivation mosaics in mice are alike in general appearance, but chimaeras are very much more variable in the proportions of the cell types (p) seen for example in coat pigmentation. The distribution of p in chimaeras is not binomial, but is uniform, or flat, between the two extremes. The g... | 632,737 | [
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Teratological evaluation of 5-fluorouracil and 5-bromo-2-deoxyuridine on hamster fetuses. | A single intraperitoneal injection of 5-bromo-2-deoxyuridine (BUDR) between days 9 and 11 and a single intramuscular injection of 5-fluorouracil (FU) between days 8 and 11 of gestation were teratogenic in hamster. The malformation frequencies were related to the dose and time of BUDR and FU treatment but the pattern an... | 632,743 | [
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Visual recognition memory for binary pictures: another look. | Recognition memory for matrices of 0s and 1s was examined as a function of the number of elements (complexity) and density of those elements within the matrix. It was found that with greater density and lesser complexity, recognition performance improved. This result contradicts an earlier finding of Green and Purohit,... | 632,758 | [
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Cholesterol in preteen children of parents with premature coronary disease. | A pediatric population at high risk for the development of coronary artery disease has been identified. Using a simple and inexpensive protocol, serum cholesterol determinations were performed on 50 children 12 years old and younger. These children were taken from 28 families in which one parent had suffered a myocardi... | 632,762 | [
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Patterns of rape and approaches to care. | The family physician is likely to be involved in the care of the rape victim. This paper focuses on the social and legal definitions of rape as well as the incidence of rape. The Rape Trauma Syndrome is explained and normative responses of victims are discussed. Eight common myths about rape are identified which the vi... | 632,765 | [
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4,9-Dihydroxyphenazine-1,6-dicarboxylic acid dimethylester and the 'missing link' in phenazine biosynthesis. | 4,9-Dihydroxyphenazine-1,6-dicarboxylic acid dimethylester, the ester form of a proposed 'missing link' in the biosynthesis of phenazines, has been isolated from a strain of Pseudomonas cepacia. | 632,805 | [
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Fast-axon synapses of a crab leg muscle. | Neuromuscular synapses of the "fast" excitatory axon supplying the main extensor muscle in the leg of the shore crab Pachygrapsus crassipes were studied with electrophysiological and electron-microscopic techniques. Electrical recording showed that many muscle fibers of the central region of the extensor muscle respond... | 632,813 | [
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Anatomical observations of the foramina transversaria. | Four hundred and eighty foramina transversaria in dry cervical vertebrae of 36 spines and in a number of dissections were studied and classified according to size, shape, and direction of their main diameter. A coefficient of roundness was then elaborated. The variations of foramina appear to follow a pattern at variou... | 632,823 | [
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Electroencephalography and phenytoin toxicity in mentally retarded epileptic patients. | There were significantly more diffuse and focal electroencephalographic abnormalities in 127 mentally retarded epileptic patients treated with phenytoin than in 68 epileptics without phenytoin. Phenytoin intoxication made the difference still more pronounced. Monitoring drug levels and electroencephalograms appears to ... | 632,825 | [
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Long-term follow-up review of patients with acute and subacute subdural hematomas. | The authors present 149 patients suffering from acute (112) and subacute (37) subdural hematomas admitted during the 10-year period 1965 to 1974, with a follow-up period of 2 to 12 years. During the time of observation, 104 patients died and 45 survived; 73% of the patients with acute and 27% with subacute subdural hem... | 632,858 | [
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Carotid paraclinoid aneurysms with intradural origin and intracavernous location. | Five cases of a congenital berry aneurysm of the internal carotid artery with origin partially intradural and fundus mainly intracavernous are presented. Angiography does not allow a precise definition of the amount of aneurysm that is intradural, a fact of importance when planning treatment of these cases. However, th... | 632,877 | [
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The role of bone scanning in osteomalacia. | The presence of eight "metabolic features" was assessed on the bone scintigrams of ten patients with osteomalacia. In all of these bone images, sufficient features were present to strongly suggest a metabolic disorder. There scintiphotos were included in a controlled blind study using 30 normal bone scans and 20 scans ... | 632,900 | [
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An optimized collimator for single-photon computed tomography with a scintillation camera. | The problem of nonuniform response, which is inherent in scintillationcamera emission computed tomography, can be minimized by proper collimator design. A specially fabricated collimator, optimized for emission computed tomography, was designed. This collimator has a calculated full width at half maximum of 1 cm at 15 ... | 632,913 | [
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A technique for the handling and dispensing of Xe-127: concise communication. | Xenon-127, which provides photon energies better suited to the Anger camera and reduces radiation dosage to the patient compared with Xe-133, has become commercially available from Brookhaven Laboratories. Its higher cost and longer shelf-life require improved handling and dispensing of shipment ampoules containing gas... | 632,932 | [
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Monitoring of I-125 contamination using a portable scintillation camera. | A technique has been developed using a portable scintillation camera to monitor I-125 contamination of personnel. The procedure takes less than a minute to complete and can detect 3 nanocuries; its use minimizes dissemination of I-125 throughout the hospital, emphasizes safe iodination practices and proper handling of ... | 632,935 | [
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Intelligence, behavior, and dysmorphogenesis in the fetal alcohol syndrome: a report on 20 patients. | In a sample of 20 patients with the fetal alcohol syndrome, ages 9 months to 21 years, the average IQ was 65, with a range of 16 to 105; 60% of the patients had IQ's more than two standard deviations below the mean. The sample included patients who ranged in severity of dysmorphogenesis from mild to severe. The severit... | 632,974 | [
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Pediatric home care: an ambulatory "special care unit". | A pediatric home care program is described which has operated as an ambulatory special care unit in an urban hospital center since 1970. The program provides care for seriously or chronically ill children, who would not be adequately served through traditional ambulatory services because of either the severity and comp... | 632,999 | [
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Plasma amino acid concentrations in newborn infants breast-fed ad libitum. | Plasma amino acid concentrations were measured in peripheral venous blood of 40 newborn infants breast-fed ad libitum. When these data are compared with amino acid concentrations of umbilical cord artery plasma, only lysine and threonine show a striking decrease after birth: the concentrations of hydroxyproline, aspara... | 633,024 | [
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A new treatment of anal incontinence in children: free autogenous muscle transplantation. | A new method is presented for the treatment of anal incontinence in children, including free autogenous muscle transplantation. The primary step is denervation of a skeletal muscle, which 2 wk later is transplanted and placed as a U-sling around the rectum, imitating the position and function of the puborectalis muscle... | 633,058 | [
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... |
Personality differences between intrinsically religious and nonreligious students: a factor analytic study. | By means of Allport's Religious Orientation Inventory (ROI) 145 students were classified as intrinsically religious and 133 as nonreligious. Personality differences between the two groups were explored on the basis of their scores on EPPS, the CPI, and 16 PF Questionnaire. Factor analysis of the combined 49 subscales o... | 633,065 | [
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0... |
Antiarrhythmic, metabolic and hemodynamic effects of Org 6001 (3alpha-amino-5alpha-androstan-2beta-ol-17-one-hydrochloride) after coronary flow reduction in pigs. | The antiarrhythmic activity of the aminosteroid Org 6001 was investigated in young pigs (20-28 kg). Ventricular arrhythmias were induced by restriction of the flow in the left anterior descending coronary artery (LAD) to 25% of its control value during a period of 30 minutes. Nine out of 30 control animals died in this... | 633,069 | [
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Afterhyperpolarization mechanism in the dorsal spinocerebellar tract cells of the cat. | 1. The longlasting afterhyperpolarization (a.h.p.) following single or short trains of spikes in dorsal spinocerebellar tract (DSCT) neurons of the cat has been studied with intracellular recording techniques. 2. The a.h.p. amplitude was found to be potential dependent, increasing with depolarization and decreasing wit... | 633,117 | [
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... |
Autonomic thermoregulation after intermittent cooling of the spinal cord and cold exposure in the rat. | 1. O2 consumption, rectal and several skin temperatures were studied, at various ambient temperatures, in unanaesthetized rats that had been thermally stressed for an average of 290 h either by prolonged and intermittent cooling of the spinal cord or by prolonged and intermittent exposure to an ambient temperature whic... | 633,137 | [
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0.0722087,
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0.484043,
-0.060103... |
Effects of phlorizin on glucose, water and sodium handling by the rat kidney. | 1. The effect of phlorizin on glucose, water and sodium handling by the kidney in anaesthetized rats was investigated, using clearance techniques, during infusion of saline (200 microliter min-1) or saline to which either low (0.1 mumole kg body weight-1 ml.-1) doses of phlorizin had been added. 2. Phlorizin increased ... | 633,141 | [
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The appearance of oestrone sulphate in the peripheral plasma of the pig early in pregnancy. | Detectable concentrations of oestrone sulphate were present in 50% of the plasma samples collected from pregnant animals by Day 17. No oestrone sulphate was detected in plasma from cyclic nonpregnant pigs. | 633,218 | [
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Results of the NIRMP for 1977. | The results of the National Intern and Resident Matching Program for the past four years show a steadily increasing number of positions offered and filled in the primary care specialties. The number of percentage of unmatched U.S. students decreased. The number of foreign medical graduates matched remained constant. Ma... | 633,336 | [
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Terminating the doctor-patient relationship. | This paper addresses a neglected area of medical student education--terminating the doctor-patient relationship. Rich clinical teaching opportunities are lost when educators fail to illustrate the significant emotional aspects of ending this highly personal affect-laden experience. The author explores these teaching op... | 633,340 | [
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DNA synthesis and thymidine kinase activity of rat colon epithelial cells fractionated by discontinuous Ficoll gradient. | Epithelial cells from colons of adult Sprague-Dawley rats were fractionated on a discontinuous Ficoll gradient at low centrifugal forces (170 x g) for approximately 60 minutes. Epithelial cells were separated into three distinct zones, whereas cell debris, yeast, and bacteria remained at the top of the gradient. The pe... | 633,399 | [
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Carcinogenicity of vinyl chloride and vinylidene chloride. | Exposure of mice to 50, 250, or 1000 ppmm of vinyl chloride (VC) in the air for 6 h/d, 5 d/wk, caused a high incidence of bronchioloalveolar adenoma, mammary gland tumors, and hemangiosarcoma. Mammary gland tumors occurred in the females and included ductular adenocarcinoma and squamous and anaplastic cell carcinomas w... | 633,405 | [
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Alterations of complement system following thermal injury: use in estimation of vital prognosis. | Complement system has been investigated in the first 15 days postburn. Complement titer (measured by a kinetic method of immune hemolysis) decreases immediately after thermal injury. This depression is mainly explained by mechanical leakage and is related to burn surface. No anticomplementary effect has ever been found... | 633,421 | [
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Growth, school attendance, and serum albumin levels in South African black children of 10-12 years. | Studies on representative series of South African Black schoolchildren aged 10-12 years revealed the following. (1) In the age sex groups, mean proportions lying below the Boston 3rd percentile of weight for age were high (a very common phenomenon), ranging from 20-84 per cent. (2) Of total moieties above and below the... | 633,429 | [
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Renal abscess in children. | Ten children with renal abscesses treated during the last 25 years are reviewed following our recent experience with 3 children, each of whom presented with an abscess. The diagnosis was not readily apparent before hospitalization, despite characteristic features of the disease. Excretory urography with nephrotomograph... | 633,488 | [
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Parasitic arterial supply to renal angiomyolipoma. | A case of a large renal angiomyolipoma in a relatively asymptomatic female subject without tuberous sclerosis is presented. The case demonstrates a parasitized blood supply from a lumbar artery and the superior mesenteric artery, in addition to the characteristic angiographic features that have been reported previously... | 633,493 | [
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Vulnerability of bot fly (Cuterebra) infected Peromyscus maniculatus to shorttail weasel predation in the laboratory. | In the laboratory, Peromyscus bearing a single Cuterebra larva are no more vulnerable to weasel predation than are uninfected control mice, and may be taken less often under certain conditions. Mice bearing two or more larvae appear to be more vulnerable than either controls or singly infected mice. Their increased vul... | 633,515 | [
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Rhabdomyolysis and acute renal failure. | Three cases of rhabdomyolysis, two with acute renal failure, seen in a short period of time in an emergency department illustrate this increasingly recognized entity. Myoglobinuria may result from muscle trauma, ischemia, metabolic causes, drug-induced injury or intrinsic muscle disorders. The diagnosis is easily made ... | 633,672 | [
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Basic decisions in Emergency Department cases: a logical approach. | In the emergency department teaching program at Brooke Army Medical Center, housestaff rotating through the emergency department are given an algorithm for use in making basic diagnostic decisions. Housestaff frequently believe that the result of their contact with a patient should be establishment of the correct patho... | 633,689 | [
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[Postoperative astigmatism and visual acuity after cataract extraction with various operative methods (author's transl)]. | The postoperative findings after cataract extraction with corneoscleral incision were compared with those after corneal incision in two groups consisting of 70 patients each. The criteria used were the degree and axis of postoperative astigmatism evaluated ophthalmometrically and the postoperative visual acuity. The pr... | 633,765 | [
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A tool and an instrument modification to facilitate aortic flow probe placement. | A tool was designed and fabricated to simplify the procedure of placing a flow probe around the aortic root in acute animal experiments. The tool was made from a section of silicone rubber tubing which was flattened and tapered at one end. The flow probe was inserted into the open end of the tool, and the tapered end w... | 633,842 | [
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The aural-overload test: twenty years later. | This paper reviews the underlying theory, the psychophysical test procedure, and the clinical applications of the aural-overload test. Clinical applications include (1) the delineation of persons susceptible to acoustic trauma, (2) the evaluation of post-exposure damage to the auditory system, (3) assistance in site-of... | 633,871 | [
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Elicitor effects on the language obtained from young language-impaired children. | Language samples are typically obtained during speech and language evaluations by the speech-language pathologist to assess the level of expressive language development of young children. These samples are assumed to be accurate representations of the children's language skills. This study examines the effects of the e... | 633,873 | [
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Individual differences in response to alcohol. Vasoconstriction and vasodilation. | Subjects who envidenced vasoconstriction after consuming alcohol did better than vasodilators on a simple motor task, but worse on more demanding tasks. | 633,895 | [
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Relationships among control orientation, the FIRO-B, and the Ward Atmosphere Scale in hospitalized men alcoholics. | Internally oriented patients' scores on Rotter's Internal-External Locus of Control Scale remained the same over treatment but those of externally oriented patients shifted toward greater internal control. | 633,909 | [
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Giant tracheoesophageal fistula: management by esophageal diversion. | Giant tracheoesophageal fistulas complicating the management of respiratory insufficiency are often difficult to close successfully because of suture line tension and narrowing of the trachea or esophagus or both. Recovery of lung function often depends on successful diversion of gastrointestinal contents from the trac... | 633,934 | [
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Effect of phase of growth and hyperlipidemic serum on the synthesis of collagen in rabbit aortic smooth muscle cells in culture. | The aim of this study was to elucidate wheter long-term cultivation in the presence of hyperlipidemic serum is able to induce changes in the rate of synthesis of collagen and other proteins by arterial smooth muscle cells. Rabbit aortic medial cells were grown in 10% sera and their collagen and total protein synthesis ... | 633,965 | [
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A model of chronic alcohol intake under free-choice conditions. | The preference of 42 Wistar male rats for alcoholic or non-alcoholic solutions of glucose was studied. Preference for the left or right position of drinking tubes did not appreciably influence the choice between the unequal solutions. Within the same strain of rats the majority of the animals had a high and a minority ... | 633,968 | [
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Evaluating inpatient costs: the staging mechanism. | Inpatient records at a short-term hospital over two years were analyzed according to the stage or degree of severity of their discharge diagnosis to examine their utilization of services. Patients with a more severe disease stage for surgical and medical conditions generated substantially higher total charges, ancillar... | 633,969 | [
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Contacts with pharmacists before and after "free" medical care--the Quebec experience. | This study reports the effects which the introduction of a national health insurance plan had upon established patterns of seeking health advice from pharmacists. Data were obtained from a household survey conducted in Montreal, Canada before and after the introduction of the government sponsored compulsory health insu... | 633,973 | [
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Mass spectrometric identification of C20 fatty acids in bovine lens using the pyrrolidide derivative. | Unsaturated C20 fatty acids from bovine lens have been examined via gas chromatography-mass spectrometry of their pyrrolidide derivatives. The presence of arachidonic acid and 5,8,11-20:3 in bovine lens has been confirmed by this study. In addition, the 10-, 11-, 12-, and 13-isomers of 20:1 and the 7,13-, 18,14-, and 1... | 634,051 | [
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0.1779595,
0.232319,
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0.01235... |
[Anticoagulation and immunosuppression in rapidly progressive glomerulonephritis of poststreptococcal type (author's transl)]. | In the majority of cases acute poststreptococcal glomerulonephritis is characterized by a good prognosis. Only relatively rare courses of this disease with clinical symptoms of rapid progressive glomerulonephritis and morphological signs of extracapillary glomerulonephritis together with crescent formation are sometime... | 634,203 | [
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[Diagnosis of sick sinus syndrome: sinus node recovery time as a bedside-investigation (author's transl)]. | Prolonged sinus node recovery time is the most important diagnostic parameter of the sick sinus syndrome. In consideration of the therapeutic proceeding (antiarrhythmic drugs, pacemaker implantation or combination of these two therapeutic measures) an exact diagnostic proceeding is desirable. In 103 atrial stimulations... | 634,216 | [
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Linearizing mechanisms in conventional tomographic imaging. | Implicit in the concept of conventional tomography and in any attempt to characterize the tomographic process by a modulation transfer function is the assumption that the tomographic process is linear. A Fourier decomposition approach and an analysis of nonlinear contributions to the integrated tomographic image intens... | 634,228 | [
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0.07560897,
-0.06378594... |
Single-step calculation of the MTF from the ERF. | A method is presented whereby the modulation transfer function can be calculated directly from the edge response function without having to find the line spread function as an intermediate step. | 634,231 | [
-0.0131462,
-0.2056098,
-0.2798039,
-0.07272656,
0.1473893,
-0.3453548,
-0.1751381,
-0.07625289,
0.08490939,
0.005143919,
-0.2319065,
-0.1429962,
0.3452738,
0.2893648,
-0.6405607,
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-0.4331598,
-0.02592595,
-0.4114013,
0.1306612,
0.4663319,
-0.01435387,
0.1993096... |
[Optical rotatory dispersion by 5 viruses of the tobacco mosaic virus group and their components]. | Optical rotatory dispersion (ORD) spectra in 250 to 350 nm region were measured for preparations of five TMV-like viruses (TMV vulgare, HR and U2 strains of TMV dolihosenation mosaic virus and cucumber virus 4) and also for RNA and protein preparations of these viruses. The data obtained testify against the possibility... | 634,280 | [
-0.02641805,
-0.02438025,
0.09976082,
0.05003262,
-0.1030682,
-0.581838,
-0.2031425,
-0.04143696,
0.2011713,
-0.1704042,
-0.03687093,
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-0.05282125,
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-0.6708285,
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-0.5912988,
0.111719,
-0.1673546,
0.02239088,
0.4325658,
0.3604396,
-0.160... |
[Study of temperature-dependent conformational changes in serum albumin using an adsorbed dye]. | 4-N (p-sulfoaniline),5-methoxy,1,2-benzoquinon (1) is bound by hydrophobic regions of the native molecule of bovine serum albumin (BSA). In the temperature interval 0--65 degrees C the interaction characteristics such as energy, entropy and the average number of the binding sites on a BSA molecule were determined. Unde... | 634,287 | [
-0.01811397,
-0.0713165,
-0.2224236,
0.04418392,
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0.05546446,
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0.1128115,
0.03294289,
0.1406783,
0.2902676,
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0.08905826,
0.1135582,
0.2073371,
0.4048,
0.2057602,
-0.009082434,
... |
The mutagenicity and cytotoxicity of selenite, "activated" selenite and selenate for normal and DNA repair-deficient human fibroblasts. | At doses varying from 8 x 10(-5) to 3 x 10(-3) M sodium selenite (Na2SeO3) induced DNA fragmentation, DNA-repair synthesis, chromosome aberrations and a mitotic inhibition in cultured human fibroblasts. The response of DNA repair-deficient xeroderma pigmentosum (XP) fibroblasts to selenite is comparable to that of cont... | 634,305 | [
-0.361775,
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0.2098792,
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0.02686335,
0.04804404,
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0.04316138,
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0.1921261,
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-0.2190679,
-0.1199534,
0.0006089981,
0.4129466,
0.04646173,
0.2067749,
-0.008609... |
Taking care of the hateful patient. | "Hateful patients" are not those with whom the physician has an occasional personality clash. As defined here they are those whom most physicians dread. The insatiable dependence of "hateful patients" leads to behaviors that group them into four stereotypes: dependent clingers, entitled demanders, manipulative help-rej... | 634,331 | [
-0.2216257,
0.0154529,
0.007156455,
-0.07591803,
0.2998325,
-0.2565531,
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0.07194734,
0.194076,
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-0.1720768,
0.008085183,
-0.08303924,
-0.2107029,
-0.3419248,
-0.1047181,
-0.4732195,
-0.04251539,
-0.09672823,
-0.04480634,
-0.05298813,
-0.2396913,
-0.... |
Muscle relaxant properties of the identified metabolites of dantrolene. | Identified metabolites of dantrolene, a skeletal muscle relaxant, were studied for inhibition of skeletal muscle contractions. Inhibition of muscle contractions were studied in vivo in the rat gastrocnemius muscle preparation, and in vitro using isolated rat diaphragm strips. Dantrolene (D) and 5-hydroxydantrolene (5-H... | 634,381 | [
-0.2103944,
0.003576682,
-0.1445551,
-0.07993797,
0.07610953,
0.2196689,
-0.2924297,
0.04566408,
0.0222205,
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0.2063413,
0.1197899,
0.276819,
-0.03267501,
-0.4249074,
0.1136632,
-0.8107322,
0.09128103,
0.002574448,
0.2641919,
0.1187316,
0.287682,
-0.1126296,
0... |
Study on incorporation of 3H-DNA in the L-cells by means of electron microscopic autoradiography. | Uptake of isologous DNA (labeled with 3H-thymidine) by L-cells was investigated by means of electron microscopic autoradiography. It was found that exogenous 3H-DNA occurred not only in the cytoplasm, but, already from the 1st hr of incubation, permeated as far as in the host cell nuclei. During continuous cultivation,... | 634,405 | [
-0.06884243,
-0.1341746,
-0.1206992,
0.126209,
0.3720466,
-0.1741152,
-0.2150787,
-0.1037833,
0.1841419,
0.2206885,
0.200294,
0.2422439,
-0.1276615,
0.3157057,
-0.6680328,
0.249632,
-0.5599142,
-0.04436564,
0.01076054,
0.241092,
0.7087179,
0.279864,
0.03154406,
-0.21791... |
Glucose-6-phosphate dehydrogenase in kidneys of lead-poisoned rats and adrenalectomized rats. | Glucose-6-phosphate dehydrogenase (G6PDH) activity, assayed biochemically, was significantly increased in kidney homogenates of lead-poisoned rats when compared with controls. Histochemically, G6PDH activity was greatly increased both in the distal tubules and the macula densa, but showed no significant changes in the ... | 634,419 | [
-0.02563255,
-0.04757531,
-0.4367104,
0.2844844,
0.03742516,
-0.2700462,
-0.1659048,
0.1428723,
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0.01429269,
0.2577265,
-0.09629566,
-0.1054108,
-0.1252015,
-0.4006882,
0.2264871,
-0.2361753,
0.3070702,
0.2178821,
0.3061588,
0.4877434,
0.3580661,
0.0750547,
0... |
[Arachnoid cyst of the cauda equina: a contribution to the etiology of coccygodynia]. | The authors report a case of arachnoid cyst of cauda equina with severe chronic coccygodynia. The value of radioculography in the diagnosis of this condition is pointed out. Resection of the cyst abolished coccygodynia completely and permanently. No case of arachnoid cyst causing coccygodynia has been found in the avai... | 634,424 | [
0.1003624,
-0.05823544,
0.04834164,
0.08272591,
-0.06753621,
-0.3181306,
-0.4809056,
-0.1840086,
0.2104183,
0.03608447,
0.2999347,
0.258245,
-0.1135795,
-0.3895429,
-0.1716238,
-0.4588617,
-0.4728894,
0.2082705,
0.03378172,
-0.154256,
0.3532167,
0.2254497,
0.1007679,
0.... |
[Case of chronic cerebrospinal memningitis with lymphocytic-monocytic reaction]. | A case of cerebrospinal meningitis was observed with persistence of cerebrospinal fluid changes during 24 months of follow up. The changes had a lymphocytic-monocytic character with pleocytosis ranging from 49 to 1500/mm3. The course of the disease was mild with meningeal signs occurring only periodically. Despite very... | 634,437 | [
-0.1650189,
-0.1174078,
0.1419889,
-0.1513123,
0.09996808,
-0.380145,
-0.3759974,
-0.1044879,
-0.1839789,
-0.04354142,
0.06831021,
0.2615126,
0.1473905,
0.1443504,
-0.2961394,
-0.2256102,
-0.3083113,
0.3294529,
-0.007325037,
0.2683811,
0.178254,
-0.1060303,
0.180979,
-0... |
[Morgagni-Larrey hernia (2 personal cases)]. | Morgagni-Larrey hernia is a rare diaphragmatic form whose time of onset is almost impossible to determine. Its symptoms, if any, are not easy to interpret. A standing X-ray of the chest is the only way in which its presence may be suspected and diagnosis must be confirmed by the use of contrast media. Abdominal or thor... | 634,492 | [
-0.1996876,
-0.07828467,
-0.03077848,
-0.08348031,
0.2777228,
-0.04240737,
-0.4673983,
-0.5288049,
-0.1018678,
-0.05245338,
0.3473674,
0.04379786,
0.05696167,
-0.5705774,
-0.09600338,
-0.2922697,
-0.4693167,
0.2260558,
-0.005935347,
0.01161132,
0.3467147,
0.1487385,
-0.11... |
[Pheochromocytoma with hypotension. Study of an unusual clinical case]. | A case of pheochromocytoma marked by clinostatic hypotensive crises and otherwise normal or low blood pressure is described. The aetiopathogenetic explanations put forward by other workers are cited and a deductive reconstruction is made of the clinical course. | 634,506 | [
-0.1922821,
-0.0796347,
-0.1255191,
-0.2572002,
0.01908229,
-0.3808765,
-0.4146213,
0.03330236,
0.1063005,
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0.2628543,
0.3636302,
-0.1000138,
-0.1303465,
-0.4152713,
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-0.04012275,
0.01113566,
0.06900203,
0.3206317,
0.07748044,
-0.02114922,
-0.105808... |
The workinghman's diet. II. Effect of weight reduction in obese patients with hypertension, diabetes, hyperuricemia and hyperlipidemia. | Weight reduction is almost always successful in cases of essential hypertension if and when the weight loss is accompanied by a drastic sodium reduction. (2) Weight normalization is of remarkable help in complete reversal of abnormal glucose tolerance, decrease in insulin requirement in manifest diabetes mellitus, and ... | 634,508 | [
0.1936288,
0.1031871,
-0.08993996,
-0.1149956,
0.4658921,
-0.2326684,
-0.06995732,
0.3364205,
0.1108853,
-0.2623979,
-0.1401195,
-0.09438512,
0.192469,
0.0697187,
-0.7300641,
-0.08855095,
-0.1879279,
0.01344625,
0.07000877,
0.0189896,
0.04124897,
0.1704917,
-0.1788375,
... |
Diabetic retinopathy in acromegaly. | A study was made of diabetic retinopathy in acromegaly. 10 of 15 patients with acromegaly had diabetes mellitus, and 3 of the 10 showed diabetic retinopathy. 2 of them had a diabetic family history. 1 patient with a diabetic family history had retinopathy of state IIIa in Scott's classification, and the other 2 showed ... | 634,558 | [
0.09820627,
-0.08616114,
0.05530439,
-0.2128075,
0.1721137,
-0.4891011,
-0.06551494,
-0.01319146,
0.02506791,
0.4114079,
0.1643724,
-0.0927944,
-0.3402502,
-0.3718053,
0.2899175,
-0.03805961,
-0.09487131,
0.06480361,
0.4781889,
-0.2497611,
0.3009605,
0.1032678,
0.09652621... |
Amniotic fluid infections with intact membranes leading to perinatal death: a prospective study. | The pathogenesis of fatal amniotic fluid infections was analyzed in a large prospective study that included more than 1,000 medical, demographic, hereditary, and postmortem variables. The disorder was the most frequent cause of death in the study, with an overall perinatal mortality of 6.17 per 1,000 births. The mortal... | 634,667 | [
-0.1196849,
-0.376361,
0.01570554,
-0.1535156,
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-0.161645,
-0.1909026,
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0.04456776,
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0.04777804,
0.07598159,
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0.2416507,
0.02259737,
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-0.255499,
-0.1016673,
-0.08665998,
0.1947562,
0.2418555,
0.04680673,
-0.1048381,
... |
Sudden death in adolescence. | The majority of adolescent deaths are sudden and unexpected; of these, the great majority result from violence. These violent deaths largely accounted for the 25% increase in total adolescent mortality during the 1960s. Yet, sudden death in adolescence is not a distinct entity and receives little study from either pedi... | 634,672 | [
-0.3148817,
-0.1265795,
-0.001139853,
-0.1694335,
0.1752705,
-0.2412789,
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0.1181883,
-0.0215404,
0.2681385,
0.5930831,
-0.2577394,
0.01588187,
-0.2867519,
-0.04336382,
-0.1069371,
0.1723382,
0.3941432,
0.2414456,
0.2411528,
0.1950359,
-0.218434,
... |
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