title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Systemic effects of the VX2 carcinoma on the osseous skeleton. A quantitative study of trabecular bone. | The skeleton of rabbits bearing the transplantable VX2 carcinoma has been studied by a combination of radiographic and histomorphometric techniques. It has previously been shown that this tumor produces and secretes large amounts of prostaglandin E2. In vivo experiments, as well as cell and organ culture studies, have ... | 628,205 | [
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Response of lymphoid leukemia L1210 in mice to implantable sustained release cytosine arabinoside capsules. | The lifespan of BDF mice with ascitic L1210 leukemia is more than doubled when they are treated with a single subcutaneously or intraperitoneally implanted sustained release cytosine arabinoside capsule. These capsules are drug-polymer composites, with dimensions of 1.0 cm in diameter and 0.15 cm in thickness, and a dr... | 628,213 | [
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Round window membrane rupture. | Round Window Membrane Rupture is a surgically correctable cause of sudden hearing loss and vertigo. Reported is a 19-year-old male who had proven round window membrane rupture secondary to barotrauma. Surgical exploration revealed an abnormally large round window niche and membrane, possibly predisposing him to this in... | 628,292 | [
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Linolenic acid deficiency: changes in fatty acid patterns in female and male rats raised on a linolenic acid-deficient diet for two generations. | Rats were fed for two generations a purified, linolenic acid-deficient diet in which the only source of lipid was purified methyl linoleate. This diet contained about 38 mg linolenic acid/kg diet. Control rats were given the same diet supplemented with methyl linolenate (2,500 mg/kg diet). Male and female rats ranged i... | 628,317 | [
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A rapid method for the determination of glycosylated hemoglobins using high pressure liquid chromatography. | Hemoglobin (Hb) Alc is a minor component of Hb found in normal individuals but elevated two or threefold in patients with diabetes mellitus. Limited studies have suggested that the level of Hb Alc is proportional to the integrated concentration of glucose over time. Thus it could serve as an index of hyperglycemia. Its... | 628,353 | [
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[Diagnostic features of the abnormal endoscopic pancreatogram (author's transl)]. | Features of 75 abnormal pancreatograms are analysed. Radiomorphology is conferred with surgical or postmortem findings in all cases. None of the anatomical alterations was found to be specific for any given diseases entity, some consistency was verified however. Solitary stenosis suggests cancer. Diffuse alterations po... | 628,363 | [
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Thyroid function after surgical treatment of thyrotoxicosis. A report of 100 cases treated with propranolol before operation. | We assessed thyroid function for 12 months after subtotal thyroidectomy in 100 tyrotoxic patients treated with propranolol alone before and immediately after operation. The operation proved safe, with low morbidity. Suppression of the hypothalamic-pituitary-thyroid axis, present in the majority one month after operatio... | 628,387 | [
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Familial hypopituitarism with large sella turcica. | We studied endocrine function in three siblings with short stature and enlargement of the sella turcica. Sellar volumes were 5.9, 3.7 and 4.0 standard deviations above age-specific means. Computed tomography or pneumoencephalography showed full sellae without suprasellar extension. Basal thyrotropin levels were low des... | 628,396 | [
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[Frequency distribution of excess weight and comparative results of somatotype aspects over a period of 8 years. Studies made in young Sicilian subjects]. | Weight excess frequency distribution with respect to ideal weight was studied in a sample of 2000 men and 2000 women from Sicily aged between 19 and 24. The following findings were made: greater representation of subjects with excess weight in the female sample (18.75%) than in the males (11.80%); about twice the perce... | 628,524 | [
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Fetal well-being in gravidas with diminished fetal activity at term. | Twenty-five patients reporting a marked diminution in fetal activity at term in otherwise normal pregnancies were compared with 25 controls, matched for age, parity, and other factors, in whom movements were reported to be vigorous. Fetal well-being was assessed by maternal serum human placental lactogen concentration,... | 628,529 | [
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Real-time sonography in obstetrics. | Three hundred fifty real-time scans were performed on pregnant women for various indications. Placental localization was satisfactorily obtained in 173 of 174 studies. Estimates of fetal gestation from directly measured biparietal diameter were +/-2 weeks of actual gestation in 153 of 172 (88.9%) measurements. The pres... | 628,530 | [
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[Electron microscopic analysis of the fibroblast differentiation of amebocytes in the common snail, Lymnaea stagnalis L. (Mollusca, Gastropoda) in a lesion focus]. | The amoebocytes and fibroblasts of intact connective tissues of the common pond snail foot, as well as the amoebocytes of the burn wound were studied by means of electron microscope. The found transitional forms from the amoebocytes to the fibroblasts allowed to conclude that there were cells--precursors of fibroblasts... | 628,550 | [
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Hypotheses in perception: their development about unambiguous stimuli in the environment. | A series of seven photographs which depict a real scene as it is approached by an observer were shown, in sequence, to ninety-six university students. The photographs were either projected colour transparencies or black-and-white prints. Two sixes of photographs were used in each set and the series was presented with o... | 628,574 | [
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A possible explanation as to why the newly sighted commonly perform well on pseudoisochromatic colour vision tests. | Patients whose vision has been restored after long periods of blindness commonly experience difficulty in perceiving. Parodoxically, such patients often perform well on pseudoisochromatic colour-vision tests. A well-known example is Gregory and Wallace's subject, S.B. who performance on the Ishihara test was perfect. I... | 628,576 | [
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Insulin allergy and insulin resistance: two immunologic reactions. | Insulin allergy and insulin resistance can cause life-threatening problems for diabetic patients. Fortunately, allergic manifestations are usually localized, but increasingly severe local reactions can precede a systemic reaction. How use of newer and purer insulin preparations than those previously available will affe... | 628,631 | [
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Variations in hepatic microsomal drug metabolism in C57Bl/6 mice from three different suppliers. | Drug metabolism by hepatic microsomal and soluble fractions was compared in male C57Bl/6 mice purchased from three different suppliers. Mice were studied at 9 weeks of age after having been purchased either as weanlings or at 8 weeks of age. Significant differences were found in the specific activity of several mixed-f... | 628,671 | [
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Effect of actinomycin D on pentagastrin- and histamine-stimulated secretion from isolated canine stomachs. | Pentagastrin- and histamine-stimulated secretion of HCl was investigated using isolated canine stomachs perfused ex vivo with homologous blood. The effect of actinomycin D, an inhibitor of DNA-dependent RNA synthesis, on the secretion of HCl by so stimulated stomachs was assessed. The purpose of this experiment was to ... | 628,677 | [
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The clinical course of patients with suspected pulmonary embolism and a negative pulmonary arteriogram. | Selective pulmonary arteriography, with superselective magnification views of the lung bases or other areas where abnormalities are shown on perfusion lung scans, performed within 24-48 hours after the onset of symptoms, can effectively rule out clinically significant pulmonary thromboembolism. One hundred and eighty c... | 628,721 | [
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Superficial esophageal carcinoma. Radiological findings in double-contrast studies. | Most cases of superficial esophageal cancer have been reported in Japan and China. Radiological findings in 11 patients (13 lesions) are described. Superficial spreading cancer is difficult to detect despite widespread mucosal involvement. Double-contrast technique is essential, both to detect lesions and to demonstrat... | 628,725 | [
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Angiographic manifestations of soft-tissue and osseous hemangiopericytomas. | Hemangiopericytomas are rare vascular tumors and may originate wherever there are capillaries. So far, the author has found 341 cases of soft-tissue and 10 cases of osseous hemangiopericytomas. Only a few of these vascular tumors have been investigated angiographically. A review of 20 previously reported cases and 5 ca... | 628,734 | [
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Double contrast arthrographic evaluation of the anterior cruciate ligament. | A review of 100 surgically confirmed cases indicates that double contrast arthrography, performed and interpreted with the described criteria, can accurately demonstrate the status of the anterior cruciate ligament. Visualization of the posterior cruciate ligament, which is less commonly injured, assures that proper ra... | 628,735 | [
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"Vascular" benign liver cyst in children: report of two cases. | Cyst wall vascularity not evident on abdominal aortography was demonstrated by selective magnification angiography in two children with complicated solitary, nonparasitic liver cysts. In one, its character and degree led to a false diagnosis of tumor. The observed mural vascularity probably reflected secondary changes ... | 628,751 | [
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Computed tomographic angiography of the body. | Large and medium-sized blood vessels can be identified on extracranial computed tomographic (CT) scans when a combination of infusion and bolus injection of conventional contrast material is administered. The cases illustrated in this report show that CT angiography can sometimes offer clinically useful information not... | 628,761 | [
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The relation between carbohydrate extraction by the forearm and arterial free fatty acid concentration in man. I. Forearm work with nicotinic acid infusion. | To see if the magnitude of carbohydrate extraction by working skeletal muscle in man is inversely correlated with the arterial free fatty acid (FFA) concentration as in the heart, eighteen healthy men were studied during dynamic forearm work with and without nicotinic acid. The extraction or release of glucose, lactate... | 628,816 | [
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An ultrastructural correlate of the membrane mutant "paranoiac" in Paramecium. | The highly organized array of intramembranous particles, the ciliary plaque, varies from the wild type in size and organization in two stocks of the Paramecium behavioral mutant, paranoiac. In one of these stocks, the alteration is dramatic. | 628,834 | [
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Middiastolic click in mitral valve prolapse. | The interesting and unusual occurrence of a middiastolic click is documented in an asymptomatic young woman with typical mitral valve prolapse. This click is shown to occur later in diastole than previously reported diastolic clicks in this syndrome. | 628,859 | [
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Hypertensive lower esophageal sphincter: a reappraisal. | The hypertensive lower esophageal sphincter (LES) is defined as one with normal relaxation and an average LES-intragastric pressure gradient greater than or equal to 40 mm Hg. Case histories of two patients with hypertensive LES and normal peristalsis in the body of the esophagus are contrasted to that of a patient wit... | 628,871 | [
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Prevention of stroke by carotid endarterectomy. | Cerebral stroke can occur in patients having visual symptoms only. Fundoscopy is valuable in identifying those patients with visual symptoms who are likely to have carotid disease; and carotid endarterectomy can prevent a stroke in a significant percentage of patients at risk. Meticulous operative technique is essentia... | 628,889 | [
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Spontaneous perforation of bile ducts in neonates. | Three neonates with spontaneous perforation of the common bile duct have been described. All were treated by laparotomy in the seventh week, with attempted closure of the perforation and a simple biliary diversion by cholecyst-jejunostomy with jejunojejunostomy below it. They have done well and represent 100% salvage o... | 628,892 | [
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[Value of different systems of mammography records with regard to their exposure to radiation and their information content (author's transl)]. | We learned from our examinations that, if there were optimum conditions, the combination Medichrome MR50 as a form of low dose method offers the same information content as the film without intensifying screens PE 4006. We found out that the discernibleness of details of 70 non selected mammographies which had each bee... | 628,932 | [
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Blue collection bag after ileal diversion. | Five children with ileal diversions have shown asymptomatic blue staining of the urine collection bags. A tryptophan derivative (indican) in the urine that oxidizes to indigo blue on exposure to air is thought to be the cause of this benign transient phenomenon. | 628,994 | [
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Genetic polymorphism of the fourth component of human complement. | A modified electrophoretic system for the determination of C4 polymorphism has been found with which the new allotype F1 could be detected. The system has been applied to the population distribution of C4 in 266 unrelated Germans, further to association and linkage studies. Gene frequency was 0.3985 for C4F, 0.5526 for... | 629,046 | [
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Febrile morbidity following vaginal hysterectomy. | The author suggests that each gynecological service determine the incidencd of febrile morbidity before adopting routine use of prophylactic antibiotics or vaginal cuff suction drainage. | 629,076 | [
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[Mathematic-statistical discrimination between suicide and accident in falls from height (author's transl)]. | On the basis of 185 deaths caused by falls from height we examined the probability to differentiate between suicide and accident. Variables about the person, about the course and the background of the action as well as about the injury-pattern were taken into consideration. Contingency table analysis, chilsqare tests a... | 629,084 | [
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[Progressive chronic polyarthritis from the viewpoint of individual psychology]. | In 106 patients with rheumatoid arthritis it could be shown by Adlerian Psychology that in more than half of the patients both physical over activity before the disease and painful inhibition of movement during the disease were an imaginary solution of the problem. Both are functions of a threatened mental and physical... | 629,095 | [
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[Mode of action of D-penicillamine in chronic polyarthritis. 1. Protein synthesis inhibition in synovial fluid cells]. | The influence of D-Penicillamine on protein synthesis in synovial fluid cells was investigated in 5 patients suffering from rheumatoid arthritis. Intra-articular injection of this substance at a dosage of 5 to 250 mg is followed by an inhibition of protein synthesis in the synovial fluid cells. | 629,096 | [
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[Mode of action of D-penicillamine in chronic polyarthritis. 2. Studies on DNA repair in synovial fluid cells following intra-articular administration of D-penicillamine]. | 6 patients with rheumatoid arthritis were treated intraarticularly with 50 or 100 mg D-Penicillamine. The influence of this substance on DNA repair in cells of synovial fluid was investigated. DNA repair was investigated by gradient centrifugation. 50 mg D-PA showed no effect, 100 mg D-PA a slight slowing of the DNA-re... | 629,097 | [
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[Neurochemical analysis of the brain structures in the formation of adaptive behavior in chicken embryogenesis]. | Studies have been made on the rate of biosynthesis of high molecular and neurospecific proteins in the hippocamp and archistriatum of chick embryos during the formation of adaptive changes in motor activity under controlled experimental conditions and unmonitored occasional stimulation. It was shown that during uncontr... | 629,116 | [
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[Cortical representation of nonclassical parts of the visual system]. | Cortical evoked potentials and extracellular evoked neuronal activity have been investigated in unanesthetized d-curarine immobilized rats during stimulation of the superior colliculi. The focus of responses was found in the lateral part of the visual neocortex (area 18a according to Krieg [5]). The evoked potential in... | 629,123 | [
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[Outpatient arrest of recidives and exacerbations in schizophrenia]. | The report contains successful results of ambulatory treatment of 54 patients with relapses of attack-like developing forms and exacerbations of continuous forms of schizophrenia. The basic principles in the treatment were intensity and dynamic influence of psychopharmacotherapeutical agents. As a rule under such condi... | 629,135 | [
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[Ophthalmocalibrometric assessment of the state of the microcirculation in the retinal vessels in transient disorders of cerebral circulation]. | The report analyses some results of a neuro-ophthalmological study of 82 patients from 34--76 years (37 males and 45 females) with transient disorders of cerebral circulation. Besides clinical studies the authors applied EEG and REG registrations, studies of the lipid metabolism, coagulative and anticoagulative blood s... | 629,136 | [
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[Role of congophilis angiopathy in the genesis of subarachnoid--parenchymatous hemorrhages in middle-aged and elderly persons]. | The author conducted a morphological analysis of 8 cases (from 61--83 years old) with extensive subarachnoidoparenchymatous hemorrhages, accompanied by expressed congofil angiopathy in different clinical processes. In 5 cases congofil angiopathy was the only lesion of cerebral vessels, in 3 cases it was combined with h... | 629,144 | [
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[Active attention and the conditioned slow negative potential in schizophrenia]. | The detected changes of conditioned slow negative potential (changes in the configuration of potentials, its increase in duration, a drop in the amplitude) as well as results of corrective tests in schizophrenic patients testify to changes in the function of active attention in this form of pathology. The authors discu... | 629,147 | [
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Mitogen stimulation of cerebrospinal fluid lymphocytes in aseptic meningitis. | The cell responses to different polyclonal lymphocyte activating substances were studied in 15 patients with aseptic meningitis by analysis of lymphocyte proliferation. The in vitro response to phytohaemagglutinin (PHA), concanavalin A (Con A) and poke weed mitogen (PWM) was investigated in blood and CSF lymphocytes si... | 629,156 | [
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Improving free play skills of severely retarded children. | Severely and profoundly retarded children are usually deficient in play skills. Since play facilitates socialization, language, and motor development, it is a vitally improtant skill to acquire. This pilot study examined the effects of a behavioral training program on the autistic, independent, and social types of play... | 629,181 | [
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Skin signs of internal malignancy. | Nonspecific dermatologic problems occasionally associated with malignant disease include pruritus, reactive erythemas and skin infections. Frequently associated with internal neoplasms are acanthosis nigricans, dermatomyositis, rapid development of multiple seborrheic keratoses, hypertrichosis lanuginosa and other synd... | 629,192 | [
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Pleural effusion. | Pleural effusion unassociated with other radiologic evidence of disease is a challenging diagnostic problem. With small effusion, only silhouetting of the diaphragm may be noted. A lateral decubitus view will often be helpful. After a careful history, physical examination and selected hematologic studies, diagnostic th... | 629,194 | [
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Blunt and penetrating abdominal trauma. | Physical examination and selected x-rays are helpful in diagnosing blunt abdominal trauma. Peritoneal lavage may assist in diagnosis of free abdominal blood. Stab wounds may be trivial injuries to the abdominal wall or penetrations of the peritoneum and underlying viscera. The "stabogram" offers some diagnostic help in... | 629,199 | [
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Modeling the uptake, metabolism and excretion of dichloromethane by man. | Data were obtained from the exposure of eleven men to dichloromethane concentrations of 50, 100, 250, and 500 ppm, 1,3 or 7.5 hours per day, for up to five successive days and from the exposure of nine women to 250 ppm on a similar schedule. Breath concentrations of the solvent following exposure were related mathemati... | 629,207 | [
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Hair as a biopsy material. V. Hair metal as an index of hepatic metal in rats: copper and zinc. | Hair copper in 500 day-old adult rats was found to correlate directly with copper in whole liver (P less than 0.001) and the subcellular liver nuclear (P less than 0.022), and cytosol fractions (P less than 0.001). An inverse correlation was found between copper in liver microsomes and plasma cholesterol (P less than 0... | 629,220 | [
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Nutrition and infant behavior: a replication study in the Katmandu Valley, Nepal. | As a cross cultural comparison with an earlier study done in West Bengal, behavioral observations were made in the Katmandu Valley of 36 well-nourished and 38 undernourished children, 7 to 18 months of age, and their mothers. Undernourished children showed lowered levels of exploratory activity and attachment behavior,... | 629,222 | [
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"Inflammatory pseudotumor" of liver with occlusive phlebitis: report of a case in a child and review of the literature. | An unusual "tumor" involving the right lobe of the liver of a young child is reported. Morphologically, the lesion had the features of "inflammatory pseudotumor." We were able to find only one previous report of a similar case in the literature. Unusual changes, which may be designated "occlusive phlebitis," were prese... | 629,225 | [
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Prosthetic-valve endocarditis due to Listeria monocytogenes. | Clinical and necropsy observations in the case of a patient with prosthetic-valve endocarditis due to Listeria monocytogenes are presented. Although rare cases of L. monocytogenes infection of natural cardiac valves have been reported, this represents the first known case of infection of a prosthetic cardiac valve by t... | 629,227 | [
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Mixed connective tissue disease in childhood. Relationship Sjögren's syndrome. | Mixed connective tissue disease (MCTD) seems to be a distinct entity that has some manifestations of systemic lupus erythematosus, scleroderma, polymyositis, and Sjögren's syndrome and is serologically characterized by the presence of an antibody to ribonucleoprotein. We report the cases of three children with MCTD wit... | 629,242 | [
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Cost considerations and sample size requirements in cohort and case-control studies. | Three methods for incorporating cost considerations into sample size determination for cohort and case-control studies are considered. It is found that when the costs of obtaining exposed and nonexposed subjects or of obtaining case and control subjects differ, an improvement in design can be achieved. | 629,257 | [
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Urban-rural differences in coronary heart disease in a low incidence area. The Puerto Rico heart study. | This report explores coronary heart disease (CHD) risk factors and the incidence of new CHD events developing over a two and one-half year period in 8793 urban and rural Puerto Rican men aged 45--64 years. Rural men had a lower average blood pressure, serum cholesterol, blood sugar, heart rate and relative weight than ... | 629,258 | [
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-0.2008556,
... |
Agreement rates between oral contraceptive users and prescribers in relation to drug use histories. | A comparison between prescriber records and patient-reported oral contraceptive histories obtained during a case-control study of thromboembolism and oral contraceptive use served as the basis for evaluating the extent of agreement between these two sources of information. Agreement between oral contraceptive user and ... | 629,260 | [
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0.1543274,
0.1839772,
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Vasoconstrictive effects of prostaglandins in sheep placental circulations. | Changes in the uterine and umbilical circulations after intra-aortic injection of prostaglandin E2 (PGE2) or protaglandin F2alpha (PGF2alpha) to either the fetus or the mother have been examined in 13 ewes at late gestation. PGF2alpha vien to either the fetus or the mother is vasoconstrictive in both uterine and umbili... | 629,284 | [
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0.1813414,
0.1260282,
0.2501087,
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... |
Cardiac output and uterine blood flow in the pregnant ewe. | Fifteen pregnant ewes were studied to determine what fractions of the increases in maternal cardiac output and oxygen consumption found in pregnancy were due to the concomitant increases in blood flow to and oxygen consumption of the uterus and its tissue contents. Maternal cardiac output rose at term to 6.65 +/- 0.47 ... | 629,286 | [
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0.1546387,
0.3467437,
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Inhibition of human neutrophil oxidative metabolism and degranulation in vitro by nitroblue tetrazolium and vitamin E. | The effect of a mixture of nitroblue tetrazolium (NBT) and vitamin E on the metabolism and ultrastructure of polymorphonuclear leukocytes (PMN) from normal subjects or patients with chronic granulomatous disease (CGD) was determined in vitro. Increasing concentrations of NBT and vitamin E progressively decreased rates ... | 629,327 | [
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0.3354279,
0.1445885,
0.383405,
0.1541851,
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Acid secretion and motility of isolated mammalian gastric mucosa and attached muscularis externa. | A procedure is described for the setting up of a preparation of mammalian gastric mucosa from kitten or ferret. The mucosa is stripped of its outer muscle coats except for a 2-mm strip of circular muscle fibers running across the diameter of the preparation. The connections of this strip to the underlying mucosa are un... | 629,348 | [
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Interdigestive motor activity of Heidenhain pouches in relation to main stomach in conscious dogs. | A great number of studies using Heidenhain pouches have been reported, but most of them have been concerned with secretory activity. Studies on the motor activity of the pouch are few, and our knowledge about it is rather limited. In the present study, therefore, long-term changes in contractile activity of the Heidenh... | 629,349 | [
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Interaction of descending spinal sympathetic pathways and afferent nerves. | With the use of computer-aided techniques, the interaction of descending spinal sympathetic pathways and afferent nerve fibers (cervical dorsal roots and tibial nerve) in regulation of thoracic (T2) preganglionic nerve activity was investigated in anesthetized, vagotomized, and paralyzed cats. High-frequency activation... | 629,359 | [
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Periventricular preoptic-hypothalamus is vital for thirst and normal water economy. | A midline stereotaxic lesion in rats destroying the periventricular tissue (lamina terminalis and preoptic-anterior hypothalamic periventricular stratum) surrounding the anteroventral third ventricle (AV3V) produces adipsia without other marked behavioral changes. Although food consumption is reduced in animals rendere... | 629,368 | [
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Blood flow distribution in the duck lung and its control by respiratory gases. | Blood flow to subunits of the lung was studied in the duck by use of radioactive microspheres. In spontaneously breathing, unanesthetized animals (series I) neopulmo was slightly better perfused than the average lung and along the paleopulmonic parabronchi, blood flow was found to decrease in the direction of ventilato... | 629,369 | [
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Changes in the satellite cells of growing muscle following denervation. | Satellite cells exhibit a number of distinct morphological changes after denervation which appear to be a direct response to nerve section or altered functional state of the muscle fibers. These changes appear generally related to increased movement and overall activation of the cells. After longer periods of denervati... | 629,408 | [
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0.03608146... |
On the development of different morphologic abnormalities of human spermatozoa. | morphologic comparisons of the live and dead sperm population gives information concerning non-lethal and lethal abnormalities. Many of the abnormalities of the sperm heads and midpieces and in particular enlarged heads belong to the latter group. On the other hand, tapering of the head, cytoplasmic droplets and abnorm... | 629,412 | [
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... |
Epizootiologic aspects of viscerotropic velogenic Newcastle disease in six pet bird species. | Pet birds of 6 species were exposed to a psittacine isolate to viscerotropic velogenic Newcastle disease (VVND) virus to evaluate the impact of VVND in those species. Species examined were the budgerigar, yellow-headed Amazon parrot, canary, halfmoon conure, lesser hill mynah, and blackheaded nun. Five of the 6 species... | 629,430 | [
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... |
Attempts to produce salivary cysts in the dog. | Attempts were made to create salivary cysts by ligation of the mandibular salivary duct at the angle of the mandible and near the frenulum of the tongue, by rupture of the mandibular duct at the angle of the mandible and near the frenulum of the tongue, and by direct trauma to the mandibular salivary gland. Cysts were ... | 629,444 | [
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0.05107261,
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-0.0228926... |
Prevalence of vesicular exanthema of swine antibodies among feral mammals associated with the southern California coastal zones. | Serum-neutralizing antibodies to both vesicular exanthema of swine virus (VESV) and San Miguel sea lion virus (SMSV) were found in a number of animal species having an association with the southern California coastal zones. California sea lions (Zalophus californianus) had antibodies to 9 VESV types (A48, C52, D53, E54... | 629,463 | [
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... |
Chemical markers of mucous and serum glycoproteins and their relation to viscosity in mucoid and purulent sputum from various hypersecretory diseases. | Mucus and serum are always present in sputum. The concentrations of their markers were measured in mucoid and purulent sputum from patients with chronic bronchitis, asthma, cystic fibrosis, or bronchiectasis. Differences in the concentrations of both mucous and serum glycoproteins were greater among different macroscop... | 629,481 | [
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... |
Delayed hypersensitivity reactions in patients with Mycobacterium chelonei and Mycobacterium fortuitum infections. | Delayed hypersensitivity reactions to skin test antigens prepared from rapidly growing mycobacteria were measured in patients with postoperative wound infections due to Mycobacterium chelonei and M. fortuitum. Sixteen of 19 patients with M. chelonei infection had more than 10 mm of induration to the M. chelonei purifie... | 629,486 | [
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... |
Predicting risk of ischemic heart disease and cerebrovascular disease from systolic and diastolic blood pressures. | The relative importance of systolic versus diastolic blood pressure in predicting risk of ischemic heart disease or cerebrovascular disease is controversial. Since 1948 we have observed in the Manitoba Study 3983 men (most between 25 to 34 years old at entry), in whom risk of both diseases was determined using the mult... | 629,496 | [
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... |
Local pulmonary immunity in pigeon breeder's disease. A case study. | We studied pulmonary and systemic aspects of the immune response in a patient with pigeon breeder's disease before and after an inhalation challenge with pigeon serum. Macrophage migration inhibition was induced with bronchoalveolar wash cells exposed to both pigeon serum and pigeon dropping extract before but not afte... | 629,498 | [
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0.2691209,
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The problem patient. Evaluation and care of medical patients with psychosocial disturbances. | The physician often finds that certain patients are poorly responsive to usual methods of therapy, especially those with somatic symptoms in whom psychosocial factors are a major, if not the sole, determinant of the illness. To care for such patients one must understand their illness as the product of mutually interact... | 629,502 | [
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0.009346... |
[Morphological changes in the digestive organs on the administration of the antineoplastic antibiotics, rubomycin and carminomycin]. | The effect of antitumour antibiotics, such as rubomycin and karminomycin on the digestive tract as one of the most vulnerable systems during chemotherapy was studied. Investigation of the tongue, oesophagus, stomach, small and large intestine of mice with the current morphological and some histochemical methods showed ... | 629,523 | [
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[Actinomyces streptomycini mutants blocked in the biosynthesis of the streptobiosamine portion of the streptomycin molecule]. | Four low active mutants of Act. streptomycini were obtained under the effect of nitrozo-methylbiuret. The mutants increased their antibiotic production level, when streptobiosamine was present in the formentation medium. It was shown that in 3 out of the 4 mutants the highest antibiotic yield was in the medium containi... | 629,525 | [
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0.121697,
0.08522249... |
[Flocculant interaction with native antibiotic solutions. An examination of the mechanism of the process]. | Some characteristics of the fermentation broth filtrates, i.e. concentration of the disperse particles and some of their parameters (projected length, area, distribution of the particles along the maximum chord) were determined and estimated after flocculation. It was shown that the floccules were mainly formed as fine... | 629,526 | [
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0.201481,
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0.13977... |
Heredity of chronic polymorphous light eruptions. | The familial occurrence of chronic polymorphous light eruptions (CPLE) was investigated by a thorough interrogation of 91 CPLE patients. Fifty-one of these were aware of the presence of one to five familial cases, a number of which were evaluated and confirmed as CPLE. The secondary cases were usually morphologically s... | 629,543 | [
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... |
Generalized argyria. Clinicopathologic features and histochemical studies. | In three cases of generalized argyria, the degree of slate-gray cutaneous discoloration varied from barely perceptible to pronounced. Deposition of silver-containing granules in and around cutaneous adnexal structures was best seen with darkfield microscopy. Histochemical studies suggested that the granules consisted o... | 629,570 | [
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Antigammaglobulin (rheumatoid factor) activity of human IgG subclasses. | A sensitive radioimmunoassay has been applied to the study of rheumatoid factor activity of IgM and IgG subclasses in serum and synovial fluid of patients with rheumatoid arthritis. Although rheumatoid factor activity was found in all four subclasses, its distribution was not the same as that of the total subclasses in... | 629,598 | [
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Neck movements in ankylosing spondylitis and their responses to physiotherapy. | Cervical spine movements were compared in 35 patients with ankylosing spondylitis (AS) and matched controls. In AS there were limitations of all movements and particularly of lateral flexion. These limitations could not be correlated with any particular features of AS except radiological involvement of the lower apophy... | 629,606 | [
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Sympathetic uveitis after trauma and vitrectomy. | A case is describes in which the earliest clinical manifestations of sympathetic uveitis that occurred after trauma and pars plana vitrectomy were confined primarily to the retina, retinal pigment epithelium, and choroid posteriorly, and resembled focal lesions of acute posterior multifocal placoid pigment epitheliopat... | 629,673 | [
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Retinal involvement in thoracic-pelvic-phalangeal dystrophy. | A patient with typical thoracic-pelvic-phalangeal dystrophy has survived to the age of 11 years with no pulmonary problem except a single episode of pneumonia at the age of 5 years. She has no evidence of renal disease. An associated ocular lesion resembled Leber's congenital amaurosis clinically but was different on e... | 629,676 | [
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0.1013602,
-0.2719785,
-0.06151002,
0.1741119,
0.1035117,
0.0588443,
... |
Ischemic optic neuropathy in cavernous sinus thrombosis. | Visual loss is uncommon in thrombosis of the cavernous sinus. A patient observed closely in the acute stages developed high introcular and intraorbital pressures. Although the retinal vasculature remained patent, total unilateral blindness occurred within 48 hours. To our knowledge this is the first documented case in ... | 629,684 | [
0.01925497,
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0.1490224,
0.1375555,
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-0.02872232,
0.1206697,
0.12633... |
Multiple-slit illumination of the optic disc. | A modification to a photo slit-lamp illuminator adds detail to the human optic disc surface by projecting onto it a pattern of fine parallel lines. These stripes curve as they traverse the disc, and its surface contour is revealed. Application of this technique may improve the reliability of methods used to quantitate ... | 629,688 | [
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0.05410004,
0.02201064,
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0.2273708,
0.0007639247,
-0.00478330... |
Intraocular irrigating solutions. A comparative study of BSS Plus and lactated Ringer's solution. | Isolated human corneas maintained normal corneal thickness and endothelial ultrastructural integrity throughout a three-to four-hour period of perfusion of BSS plus to the endothelial surface. By comparison, only one of six human corneas perfused with lactated Ringer's solution was able to maintain normal thickness and... | 629,692 | [
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0.1919795,
0.2702343,
... |
Incidence of Ménière's disease. | The incidence of Ménière's disease in Sweden for the year 1973 has been calculated as one case in a population of 2,163. This gives an overall incidence of 46/100,000. Extrapolating the Swedish incidence data to the population of the United States, there should have been 97,000 cases of Ménière's disease treated as inp... | 629,706 | [
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0.2986492,
0.07261103,
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Transport of antibiotics into the canine sinus. Experiments with penicillin G and erythromycin. | Complete and consistent occlusion of the nasofrontal duct of the canine sinus was achieved by introducing acrylic through a trephinated opening in the nasal dorsum. This surgical procedure resulted in the isolation of the frontal sinus, without impairing the integrity of the cavity. In this experimental canine model, p... | 629,710 | [
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0.346826,
... |
Risks of facial plastic surgery in an otolaryngology program. | By reviewing 680 rhinoplasty, facelift, blepharoplasty, otoplasty, and chin implant procedures that were performed during a two-year period by UCLA Head and Neck Surgery (Otolaryngology) residents, we have found that the rate of major and minor complications compares favorably with that rate achieved by physicians in p... | 629,711 | [
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0.1298469,
0.08974741,
0.480118,
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0.0129185,
0.1012701,
-0.1177437,
... |
The diagnosis of asthma. | There are three steps in establishing the diagnosis of asthma in a child presenting with recurrent wheezing or recurrent coughing. The first is to decide whether the symptoms are due to asthma, the second is to consider possible aetiological factors--mainly to reassure the parents that there is nothing particular in th... | 629,727 | [
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0.1474213,
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0.05139256,
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-0.220126,
... |
The interaction of alpha-N-(p-toluenesulphonyl)-p-guanidino-L-phenylalanine methyl ester with thrombin and trypsin. | The syntheses are described of p-guanidino-L-phenylalanine and some of its derivatives. alpha-N-(p-Toluenesulphonyl)-p-guanidino-L-phenylalanine methyl ester is an excellent substrate of bovine trypsin (EC 3.4.21.4) (Km 57 micron; kcat. 320s-1 at pH 7.4-8.0) and a very poor substrate of human thrombin (EC 3.4.21.5) (Km... | 629,742 | [
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0.07155347,
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0.2818835,
0.03880757,
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0.1587385,
-0.08884348,
0.4148766,
-0.03390095,
0.1284682,
-0.19... |
The pyridoxal-binding site in pyridoxamine-pyruvate transaminase. | The enzyme-substrate complex formed between pyridoxamine-pyruvate transaminase (EC 2.6.1.30) and pyridoxal was reduced with NaBH4. After carboxymethylation and tryptic digestion, pyridoxyl-lysine-containing peptides were isolated by a combination of Sephadex and Dowex 50 chromatography. Analysis of these peptides shows... | 629,766 | [
-0.1825547,
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-0.3829671,
0.2842869,
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0.004219233,
0.1869131,
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0.3065608,
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0.2312633,
0.09508668,
0.371138,
0.1879858,
0.4122126,
-0.2071843,
0.01... |
Studies on the mitochondrially bound form of rat brain creatine kinase. | 1. The development of the total rat brain creatine kinase was studied in brain homogenates. Until approx. 14-15 days after birth, the activity remains less than one-third that of the adult activity (207+/-6 units/g wet wt. s.d.; n=3). Over the next 10 days the activity increases markedly to the adult value and thereaft... | 629,773 | [
-0.3530347,
0.1564759,
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0.1083859,
0.05402291,
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0.3043034,
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0.2070495,
0.557855,
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0.1509827,
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0.1904554,
0.338543,
-0.03132052,
-0.1396179,
-0.... |
Oestriol-stimulated synthesis of ribonucleic acid in the uterus of the immature rat. | Oestradiol-17beta and oestriol both sequentially stimulate the synthesis of heterogeneous nuclear RNA and rRNA in vivo. However, the stimulation by oestradiol-17beta, particularly of rRNA synthesis, is very much greater than that elicited by oestriol. | 629,777 | [
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0.03138893,
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-0.1317654,
0.5710601,
-0.003339492,
-0.085... |
The mode of action of alpha sarcin and a novel assay of the puromycin reaction. | A new technique was developed for measuring the amount of peptidyl-tRNA in a protein-synthesizing system in vitro. By this technique the course of the puromycin reaction may be followed and the modes of action of various inhibitors of protein synthesis readily determined. We conclude that the polypeptide alpha sarcin i... | 629,783 | [
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0.3809972,
0.1632424,
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-0.1971359,
0.1627049,
0.2512459,
-0.05490877,
0.05688846,... |
Platelet aggregation in patients with peripheral vascular disease. | Platelet aggregation has been studied in 28 control subjects and 46 patients with peripheral vascular disease. The platelets from the patients with peripheral vascular disease were significantly more sensitive to the aggregating effects of adenosine diphosphate and adrenaline than those from the control group (P less ... | 629,826 | [
-0.1010819,
0.1095347,
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0.02226701,
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0.5353842,
0.4479145,
-0.03297531,
0.1660619... |
[Analysis of 2 studies of weight and height separated by a 50-year interval in children of Mexico City]. | The investigation of somatometric values to be used as reference patterns for Mexican children has de be scanty; the author mentions the most significant works carried out within the last 50 years. Considering that the material is comparable and in view of the magnitude of the samples, (4,757 vs. 5,533 cases) the autho... | 629,833 | [
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0.04624756,
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0.102326,
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0.06383138,
0.0920962,
0.009192291,
0.03537521,
0.1360917,
0.09733431,
-0.0990841... |
[Dermatomyositis in pediatrics]. | The study included 19 children with dermatomyositis. All showed frequently atypical cutaneous disords which in most cases were the initial manifestation. In every case there was some clinical evidence of proximal myopathy. Arthralgias were frequently found and sinusal tachycardia was present in 10 cases. The correct di... | 629,832 | [
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0.0009718158,
0.2352124,
0.1529951,
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-0.399640... |
[Reye's syndrome: pathological aspects]. | A clinical and statistical review of Reye's syndrome is made, reporting the case of a female seven months old infant with disturbances of the digestive tract associated to hepatomegaly, convulsive crises, maculopapular exanthema, extreme hypoglycemia, hyperammoniemia and high blood urea. The post-mortem study showed fi... | 629,835 | [
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0.3214094,
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-0.1562674,
0.2112114,
0.2569733,
-0.005490315,
-0.009256876,
0.1083388,
-0.028696... |
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