title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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The control of acute diarrhea in a large industrial plant. | Diarrhea causes considerable absenteeism and loss of working time among employees in the United States. One hundred employees with acute diarrhea at a Ford Motor Company plant were studied for four months to determine if loperamide hydrochloride treatment would control diarrheal symptoms, reduce absenteeism due to the ... | 641,610 | [
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Use of the one-hour blood xylose test as an indicator of small bowel mucosal disease. | The one-hour blood xylose concentration was evaluated to determine its usefulness as a screening test for small bowel mucosal disease in infants and children. Six of 13 patients with one-hour blood xylose levels of less than 20 mg/dl had normal small bowel biopsies by light microscopy. Five of 20 children with normal o... | 641,620 | [
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Treatment of neuroblastoma in mice with bromoacetylcholine and bromoacetate. | Bromoacetylcholine (30 mg/kg intratumor one to three times per day) and bromoacetate (12 mg/kg intratumor two times per day) inhibited neuroblastoma in A/J mice efficiently and prolonged the lifespan of these animals at least 200%. Since the neuroblastoma-inoculated A/J mice are considered to be comparable to human neu... | 641,717 | [
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Analysis of betamethasone and its organic esters in pharmaceutical products. | A rapid, quantitative analysis for betamethasone and its organic esters at room temperature is described. The method is similar to the official blue tetrazolium reaction for corticosteroids, except that methylene chloride is used as the solvent. The reaction is complete in 27-69 min, and the formazans produced are stab... | 641,724 | [
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Effects of paper on performance of antibiotic-impregnated disks. | Grades of paper used in the manufacture and assay of antibiotic susceptibility disks have significant effects on the diffusion of antibiotics from the paper when compared to a control grade of paper. The papers also evoke different microbiological responses to changing concentrations of some antibiotics. Regulatory imp... | 641,725 | [
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Simultaneous salt and ethanol removal from human serum albumin. | Diafiltration of salt and ethanol from human serum albumin was shown to be a competitive alternative to freeze drying. At least 99% of the original alcohol content could be removed in approximately five volume changes. Data on changes in ionic strength, bacteriological buildup, permeate flux, and dimer contents are pre... | 641,743 | [
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Constituents of West African medicinal plants XX: quindoline from Cryptolepis sanguinolenta. | An ethanol extract of the roots of Cryptolepis sanguinolenta (Asclepidaceae) afforded, after partitioning and chromatography, the alkaloids quindoline and CSA-3. The structural elucidation of CSA-3 is currently in progress. Cryptolepine was also isolated from this species. | 641,744 | [
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Micro and macro GLC determination of ethambutol in biological fluids. | Previously available GLC methods for ethambutol may only be used to measure quantities of drugs much greater than those found in biological fluids such as plasma and dialysate. A previously published GLC method for plasma samples is extended to measure ethambutol in dialysate. A second GLC method, involving derivatizat... | 641,750 | [
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Spectrophotometric determinations of 3-dimethylaminomethylkhellin hydrochloride and khellin. | Spectrophotometric assays are proposed for the determination of 3-dimethylaminomethylkhellin hydrochloride and khellin in bulk chemical and dosage forms. The acid dye method, using methyl orange at pH5, is applied to assay the amine in the form of an ion-pair extractable in chloroform with maximum abosrbance at 420 nm.... | 641,794 | [
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Spectrophotometric determination of isoniazid in presence of its hydrazones. | A spectrophotometric determination of isoniazid in the presence of its hydrazones was developed. The method involves the reaction between isoniazid and 2,3-dichloro-1,4-naphthoquinone in the presence of ammonia in an ethanolic medium. The colored product has an absorbance maxium at 640 nm. The Lambert-Beer law is obeye... | 641,804 | [
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Theoretical relationships between area under the curve and route of administration of drugs and their precursors for evaluating sites and pathways of metabolism. | The bioavailability of a drug administered extrasystemically is a measure of the initial extraction of a compound by a series of eliminating events involving the intestinal mucosal enzymes, the gut bacterial microflora, the liver, and the lung. A theoretical analysis is presented to differentiate the process of gut wal... | 641,815 | [
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Synthesis and antitumor evaluation of 4-ethoxycarbonyl cyclophosphamide analogs. | 4-Ethoxycarbonyl analogs of cyclophosphamide and its five-membered ring homolog were synthesized utilizing the cyclization method previously described. N,N-Bis(2-chloroethyl)-4-ethoxycarbonyl-1,3,2-oxazaphospholidin-2-amine 2-oxide demonstrated activity against L-1210 lymphoid leukemia whereas N,N-bis(2-chloroethyl)-4-... | 641,817 | [
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dc Polarographic determination of hydroxylaminoeverninomicin D. | An analytical procedure for a tertiary alkylhydroxylamine, hydroxylaminoeverninomicin D, was developed. It involved the autoxidation of the compound in the presence ofCu(II) and subsequent polarographic reduction. Conditions are described for the quantitative determination of the possible impurities (everninomicin D an... | 641,822 | [
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Adrenergic storage vesicles in rat heart: quantitation of membrane-bound and membrane-enclosed dopamine beta-hydroxylase. | Norepinephrine-containing storage particles in rat heart have been disrupted to determine their stability and to quantitate the amount of dopamine beta-hydroxylase (DBH) that exists in a soluble, membrane enclosed pool. Vesicles were relatively resistant to lysis by hypotonic shock or by up to five cycles of freezing a... | 641,833 | [
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Effects of aprindine HCl on slow channel action potentials and transient depolarizations in canine Purkinje fibers. | The electrophysiologic effects of aprindine hydrochloride were studied on normal Purkinje fibers, on Purkinje fibers superfused with Tyrode's solution containing 22 mM KCl and isoproterenol (1 X 10(-5) M) and on transient depolarizations induced by exposure to acetylstrophanthidin (1.7--2 X 10(-7) M). Aprindine (3 X 10... | 641,836 | [
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Calcium-mediated effects of carbachol on cation pumping and Na uptake in rat parotid gland. | Carbachol (10(-4) M), a cholinergic secretagogue, significantly increased the ouabain-sensitive uptake of 86Rb by rat parotid gland slices. This effect was blocked by the omission of Ca from the bathing medium. When extracellular Na was decreased from 125 to 5 mM, the effect of carbachol was reversed (86Rb uptake was s... | 641,839 | [
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[Oesophageal perforations from instrumentation during high fibroscopy. Radiological signs (author's transl)]. | The authors report on a survey of perforation following fibroscopy in the Hôpital Saint-Antoine. A total of 10,600 diagnostic examinations were reviewed and 5 perforations were recorded, to which must be added 2 perforations following oesophageal dilatation. A chesy X-ray, taken within 24 hours of the incident, showed,... | 641,880 | [
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Uterine DNA synthesis and cell proliferation during early decidualization induced by oil in mice. | [3H]Thymidine autoradiography was used to study cell proliferation during decidualization induced by intraluminal oil in ovariectomized mice treated with oestrogen and progesterone. Development of the decidual reaction involves two distinct populations of stromal cells. Periluminal cells start to synthesize DNA 11--15 ... | 641,890 | [
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An ultrastructural study of the human micropolycystic ovary. | The basement membrane of follicles in the micropolycystic ovaries of infertile women was thickened compared to that in the ovaries of normal women or those with typical polycystic ovaries. | 641,895 | [
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Absence of effect of maternal immunization to paternal antigens on placental weight, fetal weight and litter size in the mouse. | No evidence was obtained that immunization to paternal antigens affected placental weight, fetal weight or litter size on Day 18 of pregnancy in female mice. | 641,904 | [
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De novo simultaneous reciprocal translocation and deletion. | A female infant with severe mental retardation, general hypotonicity, and a history of generalised oedema, cyanosis, heart murmur, and nystagmus in the first days of life was found to have both a translocation and a deletion. Her karyotype was 46,XX,del(21)t(18;21)(18p ter leads to 18q11::21q21 leads to 21qter;21pter l... | 641,951 | [
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Y autosome translocation and complex chromosome rearrangement in cri du chat syndrome. | An unbalanced Y autosome translocation t(5;Y) and an apparently balanced translocation t(2;13) are identified with the Q and R banding in a 7-year-old boy with severe encephalopathy and a multiple malformation syndrome. At birth, the clinical diagnosis of 'cri du chat' syndrome based on the characteristic crying was no... | 641,952 | [
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Quantitative X-ray microanalysis of diffusible ions in the skeletal muscle bulk specimen. | X-ray microanalysis in the scanning electron microscope (SEM) is used to obtain information about the distribution and mobility of electrolyte ions in the skeletal muscle tissue. In order to localize the diffusible ions in their physiological state, so far as possible, any chemical fixative is avoided. A special 'cooli... | 641,987 | [
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Functional analysis of the shoulder girdle of cats during locomotion. | The movements of the shoulder girdle of eight adult cats during overground stepping were studied, using standard slow motion cinematographic techniques. The patterns of activity of shoulder muscles were examined, using simultaneous intramuscular electromyography. Walking, trotting and galloping steps were analyzed from... | 642,016 | [
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Brain death, apneic diffusion oxygenation, and organ transplantation. | This paper presents a simple method of maintaining good donor organ oxygenation during a prolonged test of apnea used to determine brain death prior to cadaver transplantation. Apneic diffusion oxygenation can maintain arterial pO2 above 200 torr for periods exceeding 15 minutes, thereby allowing a more definitive dete... | 642,043 | [
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Hepatic trauma and amoebic liver abscess. | A patient with a history of severe trauma over the hepatic area followed 2 weeks later by a large amoebic liver abscess of the right lobe is described. The possible role of hepatic trauma in the genesis of liver abscess is discussed. A history of hepatic trauma should not distract the clinician from diagnosing an amoeb... | 642,052 | [
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Effect of low-NaCl medium on the envelope glycoproteins of Sindbis virus. | Lowering the NaCl concentration of the medium inhibits the release of Sindbis virus from infected chicks cells at a stage after the nucleocapsids have bound to the membranes of the infected cells. The failure of trypsin treatment to release the inhibited virus and the ratio of the proteins in the inhibited cells make i... | 642,072 | [
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The prophylactic use--or misuse--of antibiotics in transurethral prostatectomy. | One hundred non-infected patients undergoing transurethral prostatectomy were randomized prospectively into a controlled study to determine the influence of a prophylactic aminoglycoside (kanamycin) on the clinical course. In the non-risk patient prophylactic kanamycin had no beneficial influence on the incidence of ba... | 642,095 | [
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0.1010117,
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0.07291819,
... |
Assisted ventilation for patients with cystic fibrosis. | Forty-six patients with cystic fibrosis (CF), 1 month to 32 years of age, had 51 episodes of assisted ventilation. Thirty-five (69%) died after 1 to 395 days of mechanical ventilation and six others (12%) died in the hospital 1 to 42 days after assisted ventilation therapy was discontinued. Only three patients survived... | 642,113 | [
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Retraining inactive physicians. A seven-year experience. | In 1969 the Medical College of Pennsylvania began a program to retrain clinically inactive physicians. Originally designed for women physicians who had discontinued their clinical training or practice in response to family responsibilities, the program has expanded its goals to encompass physicians in nonclinical caree... | 642,155 | [
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Screening for congenital hypothyroidism. Results in the newborn population of New England. | During the first year of operation, the New England Regional Hypothyroidism Screening Program determined the concentration of thyroxine (T4) levels in dried blood on filter paper from 129,028 infants born in Connecticut, Maine, Massachusetts, New Hampshire, and Rhode Island. Specimens from approximately 3,800 neonates ... | 642,171 | [
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0.2704653,
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The hemodynamics of cardiac tamponade. | The changes produced by acute pericardial tamponade were examined. Tamponade produced the expected hemodynamic alteration; namely, depression on cardiac output, left ventricular pressure and LV dp/dt and elevation of right atrial and intrapericardial pressures. The mechanism of the hemodynamic disturbances was that the... | 642,185 | [
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Electrophysiologic manifestations in so-called "sick sinus syndrome". | Electrophysiologic disorders in 17 patients with sick sinus syndrome (SSS) were assessed by recording of intracardiac electrograms, atrial overdrive pacing and extrastimulus technique. Significant suppression of the sinoatrial node (SAN) by overdrive pacing (maximum corrected SAN recovery time of longer than 560 msec) ... | 642,192 | [
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0.09145966,
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[Enucleation: causes of extrusion of orbital implants (author's transl)]. | The frequency and the causes of extrusion of orbital implants have been investigated. Of the 294 patients in which enucleation was done, in 17 cases (5.8%) extrusion of the first implant developed; in 9 cases with second or third implantations another 5 implants have been extruded. The extrusion of implants is caused m... | 642,382 | [
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... |
[Electrooculographic examination in paralytic and concomitant squint (author's transl)]. | There are shown some possibilities of electrooculographic diagnostics in different forms of strabismus. Kinetic disturbances in fusion in concomitant squint are usually frequent but not constant and in the majority they are different from incomitances in paralytic squint. In this mind electrooculography represents subt... | 642,396 | [
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0.2088... |
In vitro stimulation with mitogen and antigen in patients with monoclonal gammopathy. | Peripheral blood lymphocytes from 32 patients with defined paraproteinaemia (16 IgG, 9 IgA and 7 IgM) and from 15 healthy donors were studied for their in vitro response to various stimuli, including for unspecific mitogens such as Phytohaemagglutinin (PHA), Pokeweed mitogen (PWM) and Concanavalin A (ConA) as well as s... | 642,400 | [
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0.08953275,
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0.3... |
Platelet kinetics in Crohn's disease. | The pathogenesis of thrombocytosis in Crohn's disease was analized in ten non-treated patients using the 51Cr labelling method. The data obtained were compared to those taken from a control group. Besides platelet survival time, platelet turnover, surface radioactivity, platelet adhesiveness and morphological aspects o... | 642,410 | [
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0.004126696,
0.3340529,
0.4268954,
0.3337792,
0.00504... |
Nitrofurantoin damages DNA of human cells. | Nitrofurantoin causes damage to DNA of cultured diploid human fibroblasts. As a consequence DNA synthesis is blocked. The damage is removed by the normal enzymatic DNA repair system. Xeroderma pigmentosum fibroblasts which are defective in the excision endonuclease fail to repair nitrofurantoin-caused lesions. | 642,414 | [
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[Effect of indicator location on the psychophysiological characteristics of combined activities]. | Investigation was carried out to estimate how efficiently can combined tasks of visual measurement and sensomotor reaction of choice be performed against tracking the sinusoidal signal at different sighting angles between their displays and different priority. It was found that, with a change in the sighting angle betw... | 642,420 | [
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0... |
Two methods for producing peripheral anosmia in dogs. | Two methods for producing peripheral anosmia in the dog were described. One method involved infusion of 3.5% zinc sulfate into the nasal cavity. An anosmia lasting at least 6 weeks, and, in most cases, for several months, was produced. A second technique, producing short periods of reversible anosmia, was the insertion... | 642,437 | [
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0.03359315,
0.479... |
Long-term survival with thorotrast cervical granuloma. | Thorium dioxide, a radioactive contrast material, was commonly used for cerebral angiography prior to recognition of its radiation hazard. Extravasation of the material into the extravascular tissue in the neck results in granuloma formation, thorotrastoma, long-term morbidity, and an increased incidence of benign and ... | 642,515 | [
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0.2895841,
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0.2038697,
0.4232258,
0.05227... |
Autotransfusion of shed mediastinal blood after cardiac surgery: a prospective study. | In a randomized prospective study of patients having cardiac surgery, autologous blood collected from mediastinal tubes was autotransfused preferentially in 63 patients (ATS), whereas 51 patients received bank blood for transfusion (control). Comparison of the two groups showed no significant difference in regard to ag... | 642,556 | [
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... |
Surgery for coccidioidomycosis in 52 diabetic patients with special reference to related immunologic factors. | Fifty-two diabetic patients who underwent pulmonary surgery for coccidioiodmycosis were evaluated by a retrospective study which included classification by stage of disease, status of insulin dependency, and reaction to coccidioidin skin test. The insulin-dependent diabetic patient had a fourfold increase in the incide... | 642,560 | [
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0.0167988... |
The conducting tissues in primitive ventricle with outlet chamber. Two different possibilities. | The conducting tissues have been studied in two cases of primitive ventricle with outlet chamber. In one case the outlet chamber was to the right and in the other, to the left. In both cases there was an anterior node related to the anterior part of the right atrioventricular anulus. In the specimen with a left-sided o... | 642,572 | [
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Relationship between laryngoceles and laryngeal carcinomas. | Because X-ray evaluation of the larynx is an unreliable method of detecting laryngoceles, a study based on the systematic measurement of the ventricular depth in surgical specimens was carried out to determine the frequency of laryngoceles and their relationship to laryngeal carcinomas. The frequency of laryngoceles wa... | 642,665 | [
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The true nature of Bell's palsy: analysis of 1,000 consecutive patients. | In a series of 1502 patients seen in our Facial Paralysis Research Clinic 1048 were diagnosed as having Bell's palsy. Review of clinical, epidemiologic, and laboratory data, plus review of the literature, has led to the conclusion that Bell's palsy is an acute benign cranial polyneuritis probably caused by reactivation... | 642,672 | [
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Functional restoration for recurrent laryngeal paralysis: an experimental study. | The purpose of this investigation was to exclude abductor disturbance and to maintain phonation during recurrent laryngeal nerve paralysis through a new surgical design. This new method consists of implantation of the ansa hypoglossi and sternothyroid muscle pedicle which has been shown to provide sufficient abductor f... | 642,678 | [
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[Reproducibility of the temperature field created by a cryosurgical applicator]. | The relation between the non-reproducibility of the thermal field of the cryoapplicator and conditions of the thermal contact are reduced. Investigations of the thermal field were made on a model of tissue in a 3% aqueous gelatin solution. The results of the study show the nature of the thermal contact between the appl... | 642,752 | [
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[Increase in the information content of thermograms by compensating for tissue heat conduction]. | There exist two groups of factors responsible for distorsion of thermograms, these are a subdued temperature relief due to thermal conduction of tissues and equipment-caused distorsions. Such distorsions lower the informativeness of thermograms which hampers the selection of diagnostic signs. A method is proposed which... | 642,771 | [
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... |
[Effect of cadmium on serum level of total protein and glycoprotein carbohydrate components in rats]. | In experimental cadmium intoxication 100 rats were intraperitoneally injected with single doses of 0; 5 1,0, 2,0 5,0 mg Cd++/kg body weight as well as with 14 doses of 0,25 mg Cd++/kg. In the serum of animals the level of total protein and of glycoprotein carbohydrate components was determined. After doses in the range... | 642,794 | [
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... |
Effect of bombesin infused intrapancreatically on glucagon and insulin secretion. | Synthetic bombesin was infused at a dose of 20 pmoles/kg/min for 10 min into the cranial pancreaticoduodenal artery of anesthetized dogs. Plasma immunoreactive glucagon concentrations in the cranial pancreaticoduodenal vein as well as in the femoral artery were concurrently and slowly elevated. However, the net release... | 642,826 | [
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Follow-up study of male Liverpool graduates. | An attempt was made to trace all the male Medical Graduates from Liverpool University in the years 1950-1954 inclusive, in order to find out where they were working and what work they were doing 20 years later. Of the original group of 288 Graduates, 272 (94.4%) were both traceable and practising medicine. Of these 272... | 642,838 | [
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[Prognosis of thyroid carcinoma (author's transl)]. | Out of more than 5200 struma resections 2.2% were treated because of thyroid carcinoma. Over a 12 year' period records of 117 patients were analysed. Treatment consisted in radical thyroidectomy, radioactive iodine or radiation therapy and hormone-substitution. Differentiated carcinomas were observed more frequently, p... | 642,864 | [
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[Results of immunotherapy in 244 children with asthma or allergic rhinitis (author's transl)]. | The results of immunotherapy in 244 children with asthma or allergic rhinitis have been evaluated by means of a questionaire directed at the parents. 86,9% of the children showed improvement. Additional information has been obtained about the side-effects of therapy--2,9% regularily showed dyspnoea--, the severity of s... | 642,944 | [
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0.3784142,
0.2611135,
0.2579762,
-0.0508996... |
[Beclomethasone dipropionate seasonal allergic rhinitis treatment of children. A double blind cross over study (author's transl)]. | In a double-blind cross over study on 25 children with seasonal allergic rhinitis treatment with Beclomethasone dipropionate (BDP)-Aerosol was found more effective than placebo. 17 children preferred BDP, two the placebo-aerosol, while 6 had no preferrence. During a period with very high pollen concentrations in the ai... | 642,947 | [
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0.1200272,
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Factors predisposing to oropharyngeal colonization with gram-negative bacilli in the aged. | To assess the factors responsible for oropharyngeal colonization with gram-negative bacilli among elderly persons in institutions, we performed a cross-sectional survey of 407 volunteers, 65 years of age and older, who had not received antimicrobials in the previous four weeks. Colonization increased with level of care... | 643,028 | [
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0.2070... |
Mechanism of resistance to thiostrepton in the producing-organism Streptomyces azureus. | An antibiotic-producing organism, Streptomyces azureus, defends itself against its own toxic product by methylating the RNA of its ribosomes. | 643,068 | [
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A one-year follow-up of cystoid macular edema following intraocular lens implantation. | Retrospective and prospective techniques were used to analyze a consecutive series of 406 eyes to identify factors contributing to cystoid macular edema following lens implantation. Vitreous loss and rupture of the posterior capsule were highly significant in the production and persistence of this complication. | 643,254 | [
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Intraocular lenses: secondary membranes; cystoid macular edema. | In 650 consecutive Binkhorst lens implants, secondary membrane surgery was required more than eight times as frequently after an extracapsular than after an intracapsular cataract extraction. The visual acuity results after discussion were uniformly good. Transpars plana vitrectomy was reserved for more severe cases. T... | 643,255 | [
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[Renal glycosuria with loss of phosphate (author's transl)]. | Three of six members of one family have a renal glycosuria of variable degree. In addition to this they have a mild loss of phosphate under normal conditions. In one patient the phosphate-loss becomes very high after a loading dose. After describing the different data the mechanism of renal glucose transport and its re... | 643,293 | [
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[Hemostasis in hereditary hemorrhagic telangiectasia (author's transl)]. | The investigation of a girl aged 8 with hereditary hemorrhagic telangiectasia showed an abnormality of primary hemostasis. The bleeding time was at the upper end of normal and platelet adhesiveness was decreased to a variable extent. Platelet life span was shortened, presumably due to the telangiectatic lesions typical... | 643,297 | [
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CT whole-body scanning in pediatric radiology. | In an 8 month period 57 scans in 28 children have been performed using an EMI-CT 5005 General Purpose Scanner. Thirteen primary malignant tumours were evaluated, and scanning was of great value in localizing and delineating the lesion, and hence predicting the operability. Furthermore, secondary spread of malignant tum... | 643,351 | [
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Ileal duplication cyst: the importance of sodium pertechnetate Tc 99m scanning. | Duplications of the alimentary tract may cause extensive bleeding when ectopic gastric mucosa is present. A successful diagnosis can be made preoperatively with the use of conventional barium studies as well as sodium pertechnetate Tc 99m scans. | 643,355 | [
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Unusual presentation of appendiceal abscess on barium contrast studies. | The defect of an appendiceal abscess on a barium enema is most often seen on the medial aspect of the cecum. However, the site of involvement may vary depending on the location of the appendix. This paper illustrates some of the unusual radiographic findings that were found on barium enemas in six pediatric patients wi... | 643,358 | [
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Syndromes of congenital bowing of the long bones. | Ten patients with congenital bone disease in whom bowing of the long bones was the predominant or only sign are described. The group was composed of three patients with Campomelic dwarfism, one with long bones bowing of Caffey's type, four with femoral bowing (two of them familial), one with bowing of the long bones of... | 643,362 | [
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The role of pulmonary corticosteroid 11-reductase activity in lung maturation in the fetal rat. | Injection of 11-ketoprogesterone into fetal rats at day 17 of gestation reduced the pulmonary C-11 activation index (an indicator of net gain or loss of glucocorticoid activity) as measured at day 21 (P less than 0.001) and resulted in elevated levels of the inactive hormone 11-dehydrocorticosterone (P less than 0.001)... | 643,369 | [
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A defect in branched-chain amino acid metabolism in a patient with congenital lactic acidosis due to dihydrolipoyl dehydrogenase deficiency. | In a case of dihydrolipoyl dehydrogenase deficiency, there was not only an elevation of lactate and alpha-ketoglutarate but also of branched chain amino acids. The levels of branched-chain amino acids varied from the normal range to three times the upper limit of normal during the patient's lifetime, and alloisoleucine... | 643,378 | [
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Metabolic activity of developing rabbit lung. | The uptake and metabolism of [3H]leucine, [U-14C]glucose, and [3H]palmitate were studied in rabbits aged --3, 1, 7, 28, and 90 days up to 1--1.5 years. Although lung composition did not change markedly, there were great differences in lung metabolism between the perinatal period (late fetal and newborn) and later stage... | 643,385 | [
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Visual processing of simultaneously presented peripheral and foveal stimuli. | Results are reported for an experiment in which subjects were required to detect simple stimuli presented tachistoscopically to the periphery and/or fovea. Three modes of stimulus presentation were employed: an SMf mode in which foveal stimuli were presented alone; an SMp mode in which peripheral stimuli were presented... | 643,477 | [
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Teaching reading and writing skills to a teenaged spastic cerebral palsied person: a long-term case study. | After a 2-mo. combined reading and writing training period followed by a 1 1/2-yr. lapse, an initially 16-yr.-old paraplegic cerebral palsied boy received 1 yr. of reading training followed by 2 3/4 yr. of writing training. Reading speed increased from 5 pages/hr. to about 40 pages/hr. Tolerance for protracted reading ... | 643,491 | [
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[Ultrastructural study of experimental cerebrocortical necrosis in calves (author's transl)]. | Cerebrocortical necrosis (CCN) was experimentally induced in three calves with the thiamine antagonist Amprolium. The calves were followed clinically. At the time of development of typical clinical signs of CCN the calves were killed and necropsied and a complete histopathologic examination was performed. The light mic... | 643,542 | [
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[Systolic strangulation of the anterior interventricular artery : a rare cause of myocardial ischaemia (author's transl)]. | The relationship between myocardial ischaemia and the muscular bridge over the anterior interventricular artery with systolic strangulation has now been demonstrated. This forms part of the aetiology of angina pectoris with radiologically "normal" coronary arteries. A case is reported where the severity of the clinical... | 643,546 | [
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[Cystic pneumatosis of the small intestine following jejuno-ileal by-pass for obesity (author's transl)]. | The case reported is that of a young woman who underwent a termino-terminal jejno-ileal by-pass procedure for obesity which was refactory to usual forms of treatment. Eight months later, a cholecystectomy was carried out for lithiasis, presenting with abdominal pain. At the time of operation, lesions of cystic pneumato... | 643,580 | [
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The location of the globin mRNA sequence within its 16S precursor. | The coding sequence of globin mRNA has been located at or very close to the 3' end of its poly(A)-containing 16S precursor. The 16S RNA was annealed to globin cDNA and the hybrid digested with ribonuclease H. The undigested fragment did not bind to oligo(dT)-cellulose and its size was that expected for the intact 5' po... | 643,601 | [
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Two initiation sites for adenovirus 5.5S RNA. | Adenovirus specific 5.5S RNA is heterogeneous at its 5' terminus. Complete pancreatic RNase digests of the RNA reveal a 5' terminal oligonucleotide (pp)pApGpCp in addition to the major 5' terminal (pp)pGpGpGpCp (1). Both 5' termini are detected early as well as late after adenovirus infection. In isolated nuclei, alpha... | 643,608 | [
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Ultrasonic evaluation of "silent regions" in the thyroid scintiscan. | 35 patients with scintigraphically silent thyroid regions without palpable cold nodules were further evaluated by ultrasonography. In 33 cases the sonographic diagnosis was confirmed by other examinations or the clinical course. 2 cases were misinterpreted right at the beginning of our series. The use of ultrasonograph... | 643,627 | [
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Effect of C 21 524-Su (pirprofen) on spontaneous osteoarthrosis in the mouse. | Mice of the C57 Black strain, aged 11-12 weeks, were treated once daily on 5 days a week for 4 months with C 21 524-Su (pirprofen) in doses of 10 and 30 mg/kg p.o. In this genetically predisposed strain of mice, increases in the incidence of gonarthrosis have been observed after the administration of certain anti-infla... | 643,896 | [
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Relations between hepatotoxicity and pharmacokinetics of paracetamol in rats and mice. | A dose-dependent increase of paracetamol serum half-life (t1/2) was found after oral and intravenous application in rats and oral application in mice. The hepatotoxic effects of paracetamol were not correlated with this prolongation of t1/2. Dithiocarb protected rats against paracetamol liver damage but did not change ... | 643,897 | [
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Effects of 2-bromo-alpha-ergocryptine on the ultrastructure of anterior pituitaries in different experimental conditions. | The morphology of anterior pituitaries has been investigated by electron microscopy after administration of 2-bromo-alpha-ergocryptine (CB-154) in different experimental conditions. These include: a 1- to 5-week treatment (1 mg/kg BW, daily) to rats and a 5-week treatment (0.3 mg/kg BW, daily) to dogs, a single injecti... | 643,901 | [
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A new dosemeter for the measurement of natural ultraviolet radiation in the study of photodermatoses and drug photosensitivity. | The production and optical properties of a dosemeter for natural ultraviolet radiation are descirbed. The physical form of the dosemeter is a thin polymer film which incorporates 8-methoxypsoralen as the chromophore. The dosemeter responds to ultraviolet radiation at wavelengths up to 380 nm and is suitable for quantif... | 643,925 | [
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Effects of electromyographic feedback training on motor control in spastic cerebral palsy. | Electromyographic feedback training may play a special role in increasing active range of motion in spastic cerebral palsied individuals. The effects of electromyographic feedback training were documented on four persons with spastic diplegic cerebral palsy within a single subject design. Subjects received immediate au... | 643,933 | [
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Use of augmented sensory feedback to achieve symmetrical standing. | Ambulatory patients with hemiparesis were given auditory feedback of weight bearing on the involved leg in order to achieve symmetrical standing. A device for augmented sensory feedback, the Limb Load Monitor, was used for the training. Patients who could correct their limb loading pattern during the first treatment se... | 643,934 | [
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Staged reconstruction of flexor tendons with a silicone rod and a "pedicled" sublimis transfer. | We report the results in 11 cases of secondary flexor tendon reconstruction, employing a silicone rubber rod and a sublimis/profundus tenorrhaphy in the first stage, then hinging out the sublimis tendon on the profundus motor at the second stage. Achievement of a healed proximal tenorrhaphy before the second stage allo... | 643,962 | [
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... |
[Suicide and its ethical and legal evaluation]. | Suicide is--considering general principles to be judged both from ethical and legal viewpoints. Moreover special attentions has to be paid to the particularities of a single case and to the fact that these particularities do not recur. This is also true of the attempt to commit suicide. The "suicideprophylaxis" is of g... | 643,970 | [
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0.007207358,
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[Steps toward a therapeutic community in a psychiatric hospital (author's transl)]. | The psychiatric hospital is conceptualized as a social organism with its own development. Every important change or new development follows certain laws. When those steps of phases of development are known their unfolding can be guided more easily. Resistance must be expected and tends to hinder the planned development... | 643,975 | [
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0.05363111,
... |
[Extracranial and intracerebral vascular obstructions (author's transl)]. | Different types of extracranial and intracerebral vascular occlusion and their etiology are described. In infants the cause for cerebral vascular occlusion is infection or embolism in endocarditis. In women contraceptives evidently cause arterial thrombosis. After the fourth decade especially in men arteriosclerosis is... | 644,038 | [
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0.1898869,
0.1371111,
0.129578,
0.002552229,
0.... |
Sarcoidosis and mediastinal emphysema. | Mediastinal emphysema developed in a 13-year-old boy with diffuse interstitial pulmonary disease, later proved to be sarcoid. No previous report was found. | 644,049 | [
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0.06230596,
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0.08546528,
0.0337706,
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0.2287716,
0.2320373,
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Detection of myocardial ischemia in vitro by computed tomography. | The applicability of CT in the delineation of ischemic myocardium is defined. Twenty-six dogs had their left anterior descending coronary artery occluded, and radiolabeled microspheres were injected into the left atrium to measure myocardial blood flow. From 30 minutes to 7 weeks after coronary occlusion the hearts wer... | 644,066 | [
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0.04782592,
0.1278594,
0.007888912,
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0.03127594,
-0.023... |
[Studies on halogen quenching through the Stern-Volmer plot (author's transl)]. | The quenching effect for halogenated benzenes, methanes and ethanes have been investigated. The halogen quenching was accurately measured using the internal conversion electrons emitted from 113Sn-113mIn. From the quenching constants determined by the Stern-Volmer plots with respect to various halogen quenchers, the fo... | 644,112 | [
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0.26219,
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0.1623335,
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0.05221521,
0.1867158,
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-0... |
Renal blood flow changes following mannitol infusion. | The effect of mannitol infusion on the renal physiology, was evaluated in experimental animals and in man. In animals plasma flow and glomerular filtration rate were determined by the PAH extraction and by the innulin clearance technique. In patients renal blood flow measurements were carried out using the Xenon133 was... | 644,181 | [
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0.165651,
0.1790087,
0.1706061,
0.1630649,
-0.... |
[Articular chondrocalcinosis after 80 years of age]. | In 108 women over 80 (mean age 88,4 years, extremes 80 and 99 years) hospitalized in a geriatric service for various reasons, radiograms were made of both knees in the frontal aspect on standard film to detect calcinosis of the meniscus and chondrocalcinosis of the joint. In 25 women (23.1%) the radiographs revealed ca... | 644,241 | [
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0.2008228,
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0.2997258,
0.324311,
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0.3367994,
0.3353711,
0.1239843,
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0... |
Brain lesion diagnosis by recording cochlear and brainstem responses to sound stimuli. | A technique has been developed for the recording of the cochlear action potential (electrocochleography) and the brainstem evoked responses to click stimuli by means of earlobe and scalp electrodes with an average response computer. This technique has already proved its usefulness in diagnosis of hearing loss. Since th... | 644,258 | [
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0.09173216,
0.03446151,
-0.1621897,
0.4543474,
0.1506716,
0.0525586,
0.... |
Brain evoked potential use in a physical medicine and rehabilitation setting. | The objective of this effort was to explore the use of evoked potential (EP) procedure on a head injury unit in a Department of Physical Medicine and Rehabilitation. The method employed both auditory and visual stimulation presented bilaterally to various patients. Recordings of the brain's responses to such stimulatio... | 644,260 | [
-0.1964615,
0.04297099,
0.1623442,
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0.00975024,
-0.1642115,
0.257024... |
Potassium activation associated with intraneuronal free calcium. | Relations between calcium entry and activation of a calcium-dependent outward current during depolarization were examined under voltage clamp in dorid giant neurons injected with the calcium-sensitive photoprotein aequorin. Activation kinetics and amplitude of the slow calcium-dependent component were both found to be ... | 644,308 | [
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0.516331,
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0.1170... |
Ellipsosomes: organelles containing a cytochrome-like pigment in the retinal cones of certain fishes. | Ellipsosomes are dense spherical bodies containing a very large concentration of a heme pigment spectroscopically resembling pure cytochrome c. They are located at the outer ends of the inner segments of the cones of certain fishes. Although, superficially, they resemble the similarly located oil droplets in the cones ... | 644,317 | [
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0.3280203,
0.1225902,
0.05756397,
... |
Regeneration of symmetrical hindlimbs in larval salamanders. | The complete circle rule of the polar coordinate model of pattern regulation was tested for regenerating hindlimbs of Ambystoma larvae. The hindlimbs were made symmetrical in the circumference of either the thigh or the shank, and their ability to regenerate from both levels was observed. Thighs composed of two anterio... | 644,323 | [
-0.06490412,
0.3594162,
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0.1174989,
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0.2500392,
0.03376605,
0.3672258,
... |
Medicine: meritorious or meretricious. | In spite of remarkable advances in medical therapy and in the development of fantastic diagnostic devices, American society appears increasingly disenchanted with the physician. The paradox can be explained by the high cost of medical care, the overselling of medicine's capabilities, the expectation that the physician ... | 644,336 | [
-0.04639626,
0.262569,
-0.1410484,
0.04942165,
0.1102635,
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0.3211926,
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0.07636189,
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-0.250061,
-0.1321666,
0.0963977,
-0.1292795,
-0.2449224,
... |
Calcific constrictive pericarditis in Degos' disease. | A 31-year-old woman presented with symptoms and signs of constrictive pericarditis. She had a history of Degos' disease, a rare disorder characterized by skin and bowel lesions thought to be secondary to vasculitis. A chest roentgenogram showed extensive calcification of the pericardium. Although pleural and pericardia... | 644,373 | [
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-0.2075553,
-0.1162361,
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0.09743709,
0.3858032,
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0.2532957,
0.1390037,
-0.3400605,
... |
Chronic spinal arachnoiditis. A postoperative syndrome that may signal its onset. | Chronic lumbar radiculopathy following spinal surgery is reported, in which 7 of 25 patients reviewed developed a postoperative syndrome immediately after their original surgery. Later, sometimes years later, all 7 patients developed severe chronic spinal arachnoiditis. This syndrome was characterized by transient viol... | 644,396 | [
0.1384437,
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0.02248039,
0.1669955,
0.1577112,
-0.234990... |
Incontinentia pigmenti in a Black baby: a case report. | This is a case report of a Black baby girl who presented at the age of 7 days with incontinentia pigmenti. While the classic 3 phases of inflammation, hyperkeratosis, and irregular pigmentation are the rule, this patient demonstrates an accepted variation, presenting with irregular pigmentation without having gone thro... | 644,407 | [
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0.06553982,
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-0.3607648,
0.1636225,
0.03211263,
-0.1684... |
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