title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Tryptophan metabolism in Japanese and British women and its relationship to endogenous steroid levels. | The excretion of the tryptophan metabolites L-kynurenine, 3-hydroxykynurenine, 3-hydroxyanthranilic acid and xanthurenic acid, by normal Japanese and British pre-menopausal, menopausal and post-menopausal women was measured after a loading dose of L-tryptophan. No significant difference was found between the mean excre... | 647,965 | [
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Comparison of alkaline phosphatase isoenzymes determined by an inhibition method and by electrophoresis. | A chemical inhibition procedure suitable for the routine determination of alkaline phosphatase (AP) isoenzymes in serum has been adapted for use with a fast kinetic analyzer, System Olli 3000. The results of this procedure are compared with the electrophoretic separation of alkaline phosphatase isoenzymes. The comparis... | 647,973 | [
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Human fetal organ alkaline phosphatases. | The properties of human fetal alkaline phosphatase (ALP) have been compared with those of purified human adult hepatic and intestinal ALPs. The ALPs from different human fetal organs were divided into two groups. One terminated universal type was presented in fetal liver, spleen, adrenal, kidney, lung, heart, pancreas,... | 647,974 | [
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Glutathione and gamma-glutamylcysteine in whole blood, plasma and erythrocytes. | A method for the simultaneous determination of glutathione and gamma-glutamylcysteine in capillary blood samples is described. The whole blood levels of glutathione and gamma-glutamylcysteine are t.09 +/- 0.20 mmol/l and 25 +/- 8 mumol/l (M +/- S.D.), respectively. The plasma concentration is approximately 4 mumol/l fo... | 647,978 | [
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The influence of subacute dyflos administration on the sensitivity to agonists of longitudinal and circular muscle preparations of the guinea-pig ileum. | 1. Changes in the EC50 values to various agonists in longitudinal and circular muscle preparations of guinea-pig ileum were investigated following daily pretreatment of the animals for 10 days with dyflos (1.2 mg/kg, s.c.). 2. In the longitudinal muscle no significant change in sensitivity to acetylcholine and potassiu... | 648,035 | [
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Radiotherapists and cancer education. | This paper argues three main points. First, that education has a vital part to play in the train of events that might lead to the cure of more patients with cancer in certain sites. Secondly, evidence is presented to show that the type of education that is needed must be of a special, and carefully devised kind. And, t... | 648,092 | [
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Cytogenetic aspects of phylogeny in the Bovidae. I. G-banding. | An extensive G-banding study of karyotypes of 12 species of Bovidae has been undertaken in an attempt to trace homologies and patterns of evolution of karyotype phenotypes throughout the family. G-banding profiles revealed a considerable degree of chromosome-arm homology throughout the group, which also extended into t... | 648,196 | [
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Pulmonary hypertension in sepsis: measurement by the pulmonary arterial diastolic-pulmonary wedge pressure gradient and the influence of passive and active factors. | To examine the relative roles of passive factors (flow; filling pressures of left side of heart) and active factors (acidosis; arterial unsaturation) in the genesis of pulmonary hypertension when associated with sepsis, 37 patients with sepsis and 24 patients without sepsis were examined. Pulmonary hypertension was mea... | 648,208 | [
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Studies in heterochromatin DNA: characterization of transcripts synthesized in situ from C-banded preparations. | The transcript of in situ RNA synthesis using Peromyscus eremicus cells, which had been treated with HCl followed by NaOH, proved to be rich in heterochromatin specifying sequences. Such transcript, referred to as heterochromatin RNA, can be characterized biochemically to probe the organization of heterochromatin DNA. ... | 648,279 | [
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Giant sigmoidal diverticulum: report of a case and review of the literature. | A case report of giant sigmoidal diverticulum and a review of the relevant medical literature are presented. Only 20 cases have previously been reported. Diagnosis is dependent on a gradually enlarging mass, usually found on physicial examination. Radiologic study usually confirms the diagnosis and differentiates this ... | 648,285 | [
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Colostomies--indications and contraindications: Lahey Clinic experience, 1963--1974. | Over a 12-year period, 276 temporary colostomies were performed on 271 patients. During this interval 118 colostomies were closed. The morbidity rate of colostomy construction was 21 per cent, and for closure it was 49.1 per cent. No definite factor could be indentified as contributing to this high rate of complication... | 648,300 | [
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[Diagnostic and therapeutic aspects of early (superficial) gastric carcinoma: a retrospective analysis of 60 cases (author's transl)]. | Among 947 patients operated on for gastric carcinoma between 1961 and 1976 there were 60 with early (superficial) gastric carcinoma. All but two patients consulted their doctor for diverse complaints. In one third of them treatment was delayed for a year or longer. In 26 of the 64 cancer foci it was limited to the muco... | 648,347 | [
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[False-positive exercise ECG in women without organic heart disease (author's transl)]. | Exercise ECGs (bicycle ergometry in recumbency) were obtained in 252 women (aged 20-49 years) without evidence of organic heart disease. In 51 (20%) there was a false-positive change in the ECG with horizontal or descending S-T depression greater than or equal to 1 mm. The frequency of this change increased with increa... | 648,356 | [
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Relevance of short-term carcinogenicity tests to the study of the carcinogenic potential of urban air. | It is now accepted that screening for carcinogens in animals is expensive and demonstrates carcinogenic potential rather than actual carcinogenicity in man. A number of short-term tests which depend on mutagenicity, stimulation of DNA repair, ability to produce chromosome damage or other actions, and which correlate at... | 648,491 | [
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Splenic storage volume in the unanesthetized resting beagle. | Determination of the dog's splenic storage volume without surgical procedures requires measurement of both circulating and total red cell volumes. The estimation of circulating red cell volume by radioisotope techniques is impeded by the rapid uptake of tagged cells in the spleen. The circulating cell volume might be c... | 648,510 | [
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Inhibition of yeast phosphatidic-acid synthesis by free fatty acids. | Particulate preparations obtained from cells of yeast Saccharomyces sake have been shown to possess glycerolphosphate acyltransferase and 1-acylglycerolphosphate acyltransferase activities. Glycerolphosphate acyltransferase exhibits a high specificity for saturated and monoenoic fatty acyl-CoA thioesters. When palmitoy... | 648,519 | [
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Active-site catalytic efficiency of acetylcholinesterase molecular forms in Electrophorus, torpedo, rat and chicken. | The active sites of acetylcholinesterase multiple forms from four widely different zoological species (Electrophorus, Torpedo, rat and chicken) were titrated using a stable, irreversible phosphorylating inhibitor (O-ethyl-S2-diisopropylaminoethyl methyl-phosphonothionate). In all cases, we found that within a given spe... | 648,523 | [
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Interaction of adenylosuccinate synthetase with F-actin. | Both crude and purified preparations of adenylosuccinate synthetase from muscle were found to combine with, and dissociate from, muscle debris precipitated from a homogenate of the muscle with water. The binding and dissociation depended on ionic strength. Further study showed that the muscle enzyme was adsorbed to F-a... | 648,524 | [
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A new defect of neutrophil chemotaxis and random motility in a child with recurrent bacterial infections and hyperimmunoglobulinemia E. | A new defect of chemotaxis and random motility of polymorphonuclear leukocytes is described in a patient with severe recurrent bacterial infections since early childhood. This defect seems to be intrinsic to the cells. The patient's plasma did not contain an inhibitor of chemotaxis. Addition of plasma to the patient's ... | 648,539 | [
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Hyaline membrane disease: prognostic factors and medium-term follow-up. | One hundred and twenty two cases of severe hyaline membrane disease are reported. 68 of them survived (57%). Adverse clinical, radiological and laboratory factors, and their effects on the early mortality rate, are analysed with particular reference to the referring centers, delay in admission, transport and the critic... | 648,540 | [
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Prenatal diagnosis of beta-thalassemia using selective hemolysis of maternal cells contaminating fetal blood sample. | The prenatal diagnosis of the severe, hereditary anemias may be impossible when a placental blood sample which contains a high percentage of maternal rather than fetal cells is obtained. An incubation system described by Boyer et al. [3] with minor modifications, was applied to mixtures of blood from prematures and adu... | 648,541 | [
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The role of phagocytic cells in human blood leukocyte suspensions for in vitro colony-forming cells. | The iron ingestion method was used to separate colony stimulating cells from in vitro colony forming cells (CFU-C) in human white blood cell (WBC) suspensions. The depletion of phagocytic cells (granulocytes and monocytes) from WBC eliminated spontaneous colony growth, without influencing the total number of CFU-C. Thu... | 648,595 | [
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Cell kinetics of erythroid colony-forming cells (CFU-E) studied by hydroxyurea injections and sedimentation velocity profile. | Cell kinetic characteristics of murine CFU-E were assessed by measuring femoral marrow CFU-E survival rates after injection of hydroxyurea at from 2 to 48 h before marrow collection. The results are compatible with the concept that the CFU-E represent a homogeneous non-selfsustaining population comprised of cells belon... | 648,597 | [
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[Factorial analysis of evoked brain potentials]. | The method of main components aided to study the changes of EPs led from different brain structures during action of drugs on synaptic organizations of the brain. Two factors were singled out: the unspecific one comprised late components of EPs led from such structures as caudate nucleus, black substance; the specific ... | 648,656 | [
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Concomitant administration of timolol and hydrochlorothiazide/amiloride in hypertensive patients. Results of a titration study. | In an open dose titration study we evaluated the antihypertensive effect of the concomitant administration of timolol and hydrochlorothiazide/amiloride, administered on a b.i.d. basis. Twenty-eight out of 39 patients completed the study. Supine and standing systolic and diastolic blood pressures and pulse rate were sig... | 648,738 | [
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Nonuniform distribution and grouping of insulin receptors on the surface of human placental syncytial trophoblast. | These studies were designed to investigate the cytologic localization and topographic distribution of insulin receptors in human placental villi. Biochemical studies showed placental villi to specifically bind 125I-insulin. Radioautographic studies showed the specific binding to be localized to the surface of the syncy... | 648,742 | [
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Effects of glucose and sorbitol on proliferation of cultured human skin fibroblasts and arterial smooth-muscle cells. | To determine effects of metabolic abnormalities associated with diabetes mellitus on proliferation of diploid human cells, cultured human skin fibroblasts and arterial smooth-muscle cells were grown in media containing added glucose in the range often seen in diabetic subjects (10 to 30 mM, 180 to 550 mg./dl.). "High" ... | 648,749 | [
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[Phenocardiographic and auscultatory patterns in patients with normally functioning Björk-Shiley aortic prosthesis (author's transl)]. | Phonocardiographic examination was carried out in 40 patients who had undergone to aortic valve replacement with the Björk-Shiley prothesis. The regular function of the prothesis was evaluated on the basis of the physical, radiological and electrocardiographic data. In the majority of the cases the first sound was slig... | 648,773 | [
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[Diagnosis of pulmonary hypertension by means of noninvasive techniques (author's transl)]. | On 33 patients with mitralic heart disease (III and IV class N.Y.H.A.) we have carried out polimechanical investigations (ecg, fcg, x-ray examination, external heart impulse record) and the following parameters was determined: 1) interval Q-I sound; 2) interval II sound-OS; 3) Wells's index; 4) Q-I sound/II sound-OS ra... | 648,786 | [
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The diagnostic value of pneumoperitoneogram for splenomegaly in chronic liver diseases. | The splenic enlargement is an important symptoms of portal hypertension, and various attempts have been made to objectively describe it. But, endoscopic diagnosis for splenomegaly in chronic liver diseases may be sometimes difficult for these uncharacteristic appearances. The pneumoperitoneography was performed in 141 ... | 648,804 | [
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Gastric emptying rates of solid food in relation to body size. | The relationship of body size to rates of gastric emptying of solid food was investigated in order to obtain data that may allow this variable to be considered when populations of varying size are studied. Rates of gastric emptying were measured using a beef stew meal to which were added pieces of chicken liver tagged ... | 648,818 | [
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[Puerperal psychoses (author's transl)]. | Studies show that a hundred cases of puerperal psychoses can be divided into two major groups according to their symptomatology and their option to build recidives: those physically motivated with exogenous and endogenous symptoms and those caused by endogenous psychoses. | 648,855 | [
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[Behçet's syndrome (author's transl)]. | Descriptions of Behçet's syndrome have been appearing more and more frequently in dermatological, ophthalmological, neurological, and pathological literature as well as in the literature in the field of internal medicine. Only two reports (1, 8) have appeared in gynecological journals during the last 15 years, even tho... | 648,862 | [
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How aging affects the structure and function of the respiratory system. | Age-associated changes in the lung resemble emphysema. Progressive loss of the aging lung's static recoil forces produces airway closure at lung volumes in the tidal volume range,which leads to decreased arterial Po2. Under conditions that decrease oxygen content of arterial blood, the increase in both ventilation and ... | 648,879 | [
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Serum carbenoxolone in patients with gastric and duodenal ulcer: Absorption, efficacy and side-effects. | The absorption of carbenoxolone sodium has been studied in 15 patients with gastric ulcer and eight patients with duodenal ulcer treated for four weeks. Blood levels of carbenoxolone showed a log distribution, varied markedly between patients, and were significantly higher after Biogastrone tablets (300 mg/day) than af... | 648,939 | [
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[Particular causes of renovascular hypertension]. | Besides 55 patients with renal artery stenosis in our department 5 occlusions of renal artery and some other rare but clinically very important causes of renovascular hypertension are reported. All these casuses of an angiotensin-renin mechanism given in general the indication for operative procedure. The very low risk... | 648,990 | [
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[Obesity and cardiovascular risk]. | Epidemiological studies on the relationship of obesity, morbidity and mortality revealed the following results: In life insurance studies, excess mortality of obese people was found with more than 30 percent overweight. Mortality was caused by cardiovascular disease and diabetes mellitus. Obesity at issue of the policy... | 649,007 | [
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Genetically determined response to different ingested carbohydrates in the production of diabetes. | It has been shown that the metabolic responses to the ingestion of carbohydrates depend upon a) the type of the ingested carbohydrate and b) the genetic build-up of the recipient. In the non-susceptible animal, the ingestion of high sucrose, fructose or glucose diets will ensue in "normal" metabolic responses. In the s... | 649,046 | [
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New protein reagents. Synthesis and properties of halogenated maleimides and isomaleimides. | The title compounds were investigated as examples of potential hetero-bifunctional protein reagents having an electrophilic moiety in addition to a maleimide or isomaleimide ring. The synthesis of such products by cyclization of the corresponding maleamic acids gives lower yields in the maleimide than in the isomaleimi... | 649,055 | [
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Management and programmatic constraints on community mental health services. | While the special needs of the mentally ill are discussed in detail by society in general and by federal and state governments in particular, it is the local mental health services that must develop, integrate, and manage resources from federal and state levels and must deal with the constraints and strings attached to... | 649,067 | [
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EMS or HSA: which program model influences health delivery more? | The EMS and the HSA programs differ radically in concept of area of operation, agency structures, roles of consumers and health care professionals, method of funding, and control by the federal government. Both the government and providers should study the differing impact of the programs in order to determine which ap... | 649,079 | [
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ABC analysis helps to determine which drugs to bid purchase. | The advantages of bid purchasing to both buyer and supplier are described and an explanation of how an ABC classification of inventory helps to determine which items should be bid upon is provided. The cost savings that resulted from bid purchasing of drugs by one hospital using an ABC analysis is also described. | 649,085 | [
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Shared services in a small multihospital system. | The pressures of governmental regulation and the inevitability of NHI or catastrophic insurance programs will lead hospitals to multiinstitutional arrangements as means of survival. The experience of the Tri-County Hospital Group, Wooster, OH, suggests some optimal conditions for shared services organizations and stres... | 649,119 | [
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Right-to-die laws: creating, not clarifying, problems. | That living will, or natural death, legislation--which is currently being pushed in state assemblies nationwide--is unnecessary and may actually inhibit physicians in providing the best of care to dying patients is evident from an analysis of the statutes that have been passed. Whether the motivation behind such legisl... | 649,133 | [
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Cytogenetic study in spermatocytes of mice and Chinese hamsters after treatment with isoniazid (INH). | Meiotic chromosomes of spermatocytes from INH-treated male mice and Chinese hamsters were analysed for chromosome aberrations in diakinesis-metaphase I and metaphase II. The experiments were performed in two laboratories while a third laboratory participated in the chromosome evaluation. No enhancement of chromosome ab... | 649,168 | [
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The effect of SH-SS transition in the structural organization of mitotic chromosomes. | Human lymphoid cell cultures were treated with 2,2'-dithiodipyridine, a thiol reacting agent which produces SS bridges inside the living cells. After 1 to 4 h treatment chromosome preparations were made. The chromosomes acquired a peculiar segmentation along the chromatids. The results suggest that the alteration might... | 649,172 | [
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Traumatic hemipelvectomy--the tenth survivor: a case report and a review of the literature. | This tenth survivor of traumatic hemipelvectomy was a young male involved in a collision between a car and his bicycle. As in previous cases, he sustained severe associated injuries to the genitourinary tract and rectum. Atypically he required secondary closure with autogenous skin taken from the severed lower limb, an... | 649,196 | [
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Malignant change in a verrucous nevus. | A 41-year-old man developed squamous-cell carcinoma within a verrucous nevus of linear distribution of a long duration. Controversial cases have been reported in the literature. Such malignant change in verrucous nevus is extremely rare. | 649,251 | [
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Treatment of psoriasis: trioxalen and sunlight. | Eighteen psoriasis patients were treated alternately with 40 mg of trioxalen and sunlight on the right side and sunlight only on the left side. Improvement was apparent faster on the psoralen-exposed side. | 649,253 | [
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Studies on polypeptides. XXVI. Synthesis of the N-terminal 1--23 peptide sequence of rat pancreatic ribonuclease; enzymatic activity of the hybrid complex with bovine S-protein. | A description is given of the synthesis by fragment condensation of the peptide Gly-Glu-Ser-Arg-Glu-Ser-Ser-Ala-Asp-Lys-Phe-Lys-Arg-Gln-His-Met-Asp-Thr-Glu-Gly-Pro-Ser-Lys corresponding to the 1--23 amino acid sequence of rat pancreatic ribonuclease. This rat peptide combined with bovine S-protein yields a fully active... | 649,256 | [
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Emotional aspects of heart disease: a personal narrative. | It is not particularly profound to note that one's choice of a professional career is related to unconscious motivational forces, and that a desire to become a physician may stem from a wish to conquer one's own illness and the inevitability of death. Once one becomes a physician his personal experience with illness ma... | 649,268 | [
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Teaching psychiatry in medical school. | Considerable dissatisfaction of students and educators exists in regard to the teaching of psychiatry in medical school. This paper recommends that the liasion model of teaching directed to house and attending staffs be applied to the teaching of medical students during their clerkships throughout the general hospital,... | 649,265 | [
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"The child is father to the man": dependency in professional relationships. | This situation where two or more members of different professions are working jointly with the same client or patient is compared to the way the relationship between parents affects their children. It is suggested that stress inclines colleagues to infantile patterns of relationship, one partner being dominant and the ... | 649,280 | [
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A histochemical study of the effect of phenol on the mitochondria and lysosomes of cultured cells. | This study was undertaken to assess the effect of a known cytotoxic substance on the permeability of the organelle membranes of cultured cells. BHK-2-1 (C-13) cells were grown as monolayers on glass cover-slips and exposed for 1 h to 1 mg/ml and 2 mg/ml phenol. The cover slips were recovered and incubated for the demon... | 649,443 | [
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Social, legal, and therapeutic changes that should lessen the traumatic effects of divorce on children. | Easing the plight of the divorcing and the divorced requires the efforts of a broad range of professional disciplines. It is not my purpose here to cover in detail the various ways in which different professionals can contribute to this goal. Rather, I will focus on certain specific changes which, if implemented, could... | 649,462 | [
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Regulation of breathing in newborns at high altitude. | Resting respiratory parameters and respiratory responses to acute changes in end-tidal O2 and CO2 pressure (PETO2 and PETCO2) were investigated in Peru in 23 newborn and 4 older infants at 3.850 m and in 13 newborns at 800 m. The study was done with the subjects asleep in a thermoneutral environment. The transient incr... | 649,468 | [
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-... |
The epithelial innervation of the lower respiratory tract of the cat. | A quantitative ultrastructural study of intra-epithelial axons in the lower respiratory tract of the cat has compared the innervation at four airway levels, two extra- and two intrapulmonary. The morphology of intra-epithelial axons has been described, and their association with different epithelial cell types recorded... | 649,493 | [
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The thickness of the cartilage in the hip joint. | The pattern of distribution of cartilage thickness in corresponding femoral heads and acetabula was ascertained in ten hip joints. The differences between individual acetabula and their corresponding heads were small enough for it to be admissible to calculate an average distribution pattern for head and socket. Compar... | 649,495 | [
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On the calibre of the ureteric lumen. | The cross sectional appearances of the lumen of rat ureter were compared in specimens fixed by perfusion and by immersion and processed for electron microscopy. After efficient perfusion fixation in untreated animals, and in animals previously injected with 6-hydroxydopamine, there was substantial dilatation of the ure... | 649,499 | [
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0... |
The comparative anatomy of the blood supply of cardiac ventricles in the albino rat and guinea-pig. | The hearts of 118 albino rats and 80 guinea-pigs were investigated by angiography. It was found that the blood supply to the cardiac ventricles of the rat is a coronary balanced circulation similar to that frequently met with in man. On the other hand, the distribution of the coronary arteries in the guinea-pig showed ... | 649,502 | [
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An electron microscopic study of the adductor externus superficialis muscle associated with the venom gland of the cobra (Naja naja). | The adductor externus superficialis muscle closely envelops the venom gland in the cobra (Naja naja). Only twitch fibres are present in the muscle, supporting the view that the muscle is concerned with the rapid evacuation of venom. 'Satellite' cells are readily observed in relation to the muscle fibres. | 649,503 | [
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Gas-liquid chromatographic determination of nitrate and nitrite in cheese, ham, fish sausage, cod roes, and salmon roes. | The 2,4-xylenol method was modified and a gas-liquid chromatographic (GLC) method was developed for nitrate and nitrite determinations in several foods. Either a flame ionization (FID) or an electron capture detector (ECD) can be used. Proteins and fats are removed from warm alkaline water with zinc sulfate and filtere... | 649,543 | [
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Rapid thin layer chromatographic method for determining aflatoxin B1, ochratoxin A, and zearalenone in corn. | A multimycotoxin thin layer chromatographic method is described for the analysis of corn. Aflatoxins are extracted from the samples with acetonitrile-water, and sodium bicarbonate is added to separate the acidic ochratoxin from zearalenone and aflatoxin B1. After chloroform extraction, 1N NaOH is added to separate zear... | 649,550 | [
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Atomic absorption spectrometric determination of cyhexatin in apples. | A rapid method using atomic absorption spectrometry has been developed for determining residues of cyhexatin in apples. Each analysis takes less than 30 min and the method is sensitive to less than 0.1 mg cyhexatin/kg. Recoveries varied from approximately 100% at 0.25 and 0.05 mg/kg to 70% at 5 mg/kg. No acid digestion... | 649,555 | [
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0.01579578,
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Atomic absorption spectrometric and colorimetric determination of iron in seafoods. | Iron levels in 14 seafoods were determined by atomic absorption spectrometry (AAS) on freeze-dried composites. Samples were prepared for analysis after dry-ashing at 550 degrees C and wet digestion in HNO3-HClO4. Paired analysis of wet digests were accomplished by AAS and use of the colorimetric reagent, ferrozine. The... | 649,563 | [
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... |
Glucagon treatment stimulates the metabolism of hepatic submitochondrial particles. | Hepatic submitochondrial particles, prepared at neutral pH from rats pretreated with glucagon, exhibited stimulated rates of State 3 and uncoupled respiration when succinate or NADH were the substrates, but not when ascorbate plus N,N,N',N'-tetramethyl-p-phenylenediamine were employed. Measurements of 8-anilino-1-napht... | 649,575 | [
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0.1769... |
The renaturation of reduced chymotrypsinogen A in guanidine HCl. Refolding versus aggregation. | The refolding and reoxidation of fully reduced and denatured chymotrypsinogen A have been studied in the presence of low concentrations of guanidine HCl or urea. Renaturation yields of 60 to 70% were observed when the reoxidation was facilitated by mixtures of reduced and oxidized glutathione. Refolding occurred within... | 649,582 | [
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Characterization of gangliosides from bovine erythrocyte membranes. | Two glucosamine-containing gangliosides, sialosylhexaglycosylceramides, were isolated from bovine erythrocyte membranes. Both gangliosides were hydrolyzed by neuraminidase isolated from Clostridium perfringens to become neutral hexaglycosylceramides. Based on the results of sequential enzymatic hydrolysis and gas chrom... | 649,619 | [
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Biocompatibility testing of polymers: in vivo implantation studies. | An in vivo method is described for screening polymeric materials for biocompatibility. The test is based on grading acute and subacute tissue reactions at 7 and 28 days, respectively, following implantation in rats. The methods is reproducible and reliable. It is designed to provide uniform test criteria for biocompati... | 649,628 | [
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... |
Sacral agenesis. | Twenty-three patients with sacral agenesis evaluated at Newington Children's Hospital between 1959 and 1977 were classified according to patterns of morphologic deficiency in the bones and articulations. Motor deficit in these patients corresponded, within one level, to vertebral loss; sensory deficit did not correspon... | 649,642 | [
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... |
[Carcinomas of the transverse colon. A series of 75 cases (author's transl)]. | The authors report a series of 75 cases of carcinoma of the transverse colon, involving equally the right and left halves. They rarely arose from the middle segment (10% of the series). Usually the tumour was very large affecting the serous layer with lymph node invasion. Liver metastases were frequent. 50% of patients... | 649,703 | [
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Chromatographic profile of high boiling point organic acids in human urine. | The profile of high boiling point organic acids in urine samples from both normal subjects and patients suspected of having some form of metabolic disorder has been determined by combined gas chromatography-mass spectrometry. Fifteen different compounds eluting after hippuric acid have been identified, including two, c... | 649,712 | [
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Quantitative estimation of salicylic acid and its metabolites by thin-layer densitometry. | A rapid thin-layer densitometric method for the quantitative determination of salicylic acid and its metabolites in urine or plasma is described. The method is specific and very sensitive. Nanogram quantities of salicylic acid and its metabolites, both free and conjugated, may be estimated. Known metabolites, as well a... | 649,744 | [
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0.0451... |
Comparison of radial haemolysis with haemagglutination inhibition in estimating rubella antibody. | Radial haemolysis (RH) for assaying rubella antibody was studied in parallel tests with haemagglutination-inhibition (HAI) on 1102 sera from adult women. Simple to perform and economical in reagents, the RH test is as sensitive as the HAI test and is a useful method of screening antenatal and other sera for rubella imm... | 649,774 | [
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... |
Converging projections from the mediodorsal thalamic nucleus and mesencephalic dopaminergic neurons to the neocortex in three species. | Previous studies in the rat have shown that the neocortical dopaminergic afferents, originating in the mesencephalon, terminate in those areas of the frontal lobe which receive projections from the mediodorsal thalamic nucleus i.e., the prefrontal cortex. In order to clarify whether this overlap is accidental for the r... | 649,789 | [
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Studies of visual function and its decay in mice with hereditary retinal degeneration. | Functional implications of mouse hereditary retinal degeneration have been studied at the level of the superior colliculus and visual cortex in the C57BL/6J-le rd strain. On autoradiography at a light-microscopic level, following eye injection with radioactive compounds, central visual structures appeared normal. A sli... | 649,791 | [
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Tinea versicolor: a scanning electron microscopic view. | Tinea versicolor (TV) infections were studied in the scanning electron microscope utilizing several different sampling and preparatory techniques. Scalpel scrapings provided information only on the morphology of individual spores and hyphae, while biopsies and cyanoacrylate adhesive slides demonstrated the topography o... | 649,793 | [
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Two-tone suppression in auditory nerve of the cat: rate-intensity and temporal analyses. | Responses to two-tone stimuli were recorded from auditory-nerve fibers in anesthetized cats. One tone, the suppressor, was set at a frequency above characteristic frequency and was fixed in intensity. A second tone was set at an excitatory frequency and was varied in intensity. The suppressor tone, when set at a suffic... | 649,868 | [
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Pitch and pitch discrimination of broadband signals with rippled power spectra. | A random-interval pulse train or wide-band noise when delayed (tau) and added back to itself (cos+) produces a stimulus with a consinusoidally varying (or trippled) power spectrum. The spacing between the peaks in the spectrum is equal to the reciprocal of the delay (1/tau). If the stimulus is delayed and added back at... | 649,875 | [
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A method for training and evaluating the reception of ongoing speech. | The "tracking procedure" is a method to train and evaluate the reception of ongoing speech. A talker and a receiver engage in a dialogue for a designated period of time in which the receiver reports his perception of successive segments of read text and is corrected by the talker until the text is repeated verbatim. Pe... | 649,877 | [
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0.07079966,... |
Correlational study of speakers' heights, weights, body surface areas, and speaking fundamental frequencies. | The purpose of this investigation was to determine the relationship among speakers' heights, weights, body surface areas, and speaking fundamental frequencies. The recordings of 30 speakers' readings of a standard prose passage were analyzed by means of the Fundamental Frequency Indicator (FFI) to obtain their speaking... | 649,880 | [
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... |
Vision and sports. | The relationship between optimal visual skills and optimal athletic performance is discussed along with specific examples of how performance can be affected in tennis, basketball, football, baseball, and golf. A step-by-step method is presented to evaluate these specific skills during the optometric evaluation. | 649,918 | [
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Cellular assay for measuring anti-erythrocyte antibody responses. | Splenocytes from mice immunized with sheep red cells (SRC) or donkey red cells (DRC) were able to lyse radiolabeled SRC or DRC respectively. The cytotoxic effect was mediated by the active supernatant which was released from the immune splenocytes and which was characterized as antibody. This cellular cytotoxic respons... | 649,962 | [
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Haemagglutination assay for HBsAg -- a new approach to reagent preparation. | Human group O rhesus negative erythrocytes were spherocyted and fixed in glutaraldehyde, then coated initially with HBsAg and subsequently with anti-HBs. The resulting reagent was found to agglutinate in the presence of HBsAg positive serum, but not in HBsAg negative serum. The assay was evaluated for blood donor scree... | 649,965 | [
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-0.1162565,
-0.3982288,
0.1562389,
0.1520014,
-0.1938295,
-0.09485064,
... |
An improved method for detection and titration of antibodies cytophilic for macrophages. | A new microtechnique for detection and titration of antibodies cytophilic for homologous macrophages is introduced and experiments designed to determine the optimum conditions for its performance reported. The technique employs a series of small chambers formed on a microscope slide by the application of a plastic film... | 649,966 | [
0.1024287,
0.02865592,
0.06884715,
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0.0422415,
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-0.3449367,
0.3213972,
0.235014,
0.1245286,
0.0546517,
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0.1994038,
0.2666734,
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-0.1556599,
0.4629121,
0.2205903,
-0.008171019,
-0.01089851,
... |
Plasma immunoreactive beta-melanocyte-stimulating hormone in chronic liver disease and fulminant hepatic failure. | Hyperpigmentation believed to be due to melanin, is a feature of chronic liver disease, especially primary biliary cirrhosis and hemochromatosis. Normal plasma concentrations of immunoreactive beta-melanocyte-stimulating hormone (beta-MSH) have been found in both these conditions; thus elevation of plasma beta-MSH play... | 649,979 | [
-0.3482561,
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0.316788,
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0.0788166,
0.03751056,
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0.1314263,
0.1423268,
0.2579212,
0.1616129,
0.1461652,
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0.1238806,
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0.2267208,
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0.3382335,
0.04874444,
-0.1675626,
-0... |
Effects of ultrafiltration on solute clearances in cuprophan and cellulose hollow fiber dialyzers: in vitro and clinical studies. | Hollow fiber dialyzers are currently available with either regenerated cellulose or thinner walled cuprophan fibers. In vitro and clinical studies were undertaken to compare a cellulose with a cuprophan dialyzer in regard to (1) UF's, (2) small and large solute clearances at high and low TMP's, (3) SC's, and (4) effect... | 650,063 | [
-0.05684968,
-0.1860705,
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0.02820808,
0.08079474,
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0.03772553,
0.0907185,
-0.05106527,
0.327713,
0.2229147,
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0.1350555,
0.272271,
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-0.05656828,
-0.2296807,
-0.02615154,
-0.06319578,
0.1803872,
0.0438682,
... |
Structural polypeptides of measles virus. | The structural polypeptides of two strains of measles virus grown in Vero cells were analysed in SDS-PAGE slab gels. Six major polypeptides were identified with mol. wt. of 79000, 72000, 60000, 43000, 40000 and 36000. The largest polypeptide was sensitive to trypsin digestion and was the dominant glycosylated polypepti... | 650,174 | [
-0.4061257,
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-0.3031261,
0.1288166,
0.1930461,
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0.201548,
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0.0476365,
0.05328986,
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0.09873144,
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0.1929384,
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0.03895741,
-0.243123,
0.1141918,
0.4664912,
0.04026915,
-0.3022517,
-0.... |
Inhibition of African swine fever (ASF virus replication by phosphonoacetic acid. | Phosphonoacetic acid (PAA) inhibits the multiplication of African swine fever (ASF) virus in VERO cells. The observed inhibition of the in vivo DNA synthesis could be related to the in vitro inhibition of a virus-induced DNA polymerase activity present in cytoplasmic extracts from infected VERO cells. | 650,176 | [
-0.171543,
0.1384898,
-0.1888578,
-0.02396913,
0.1299928,
0.1473812,
0.03301023,
0.03616246,
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0.01477529,
0.1611665,
0.1345178,
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0.07240366,
-0.08259831,
0.4112137,
0.290332,
-0.01944039,
-0.4673094,
... |
Amino acid requirement of adenovirus multiplication. | The absence from the medium of any of the 13 amino acids essential for cell growth has an inhibiting effect on the multiplication of adenovirus 9-15 and adenovirus I in HeLa cell cultures. The inhibition is accentuated by previous amino acid starvation of the cultures. Whereas with arginine deprivation, the arginine po... | 650,177 | [
-0.2341683,
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-0.03511678,
0.2961114,
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0.1358218,
0.08055054,
0.01141208,
0.4327113,
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0.1534896,
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0.2715205,
-0.3806902,
-0.1521138,
-0.3236454,
0.2299542,
0.3696724,
0.08536264,
0.05319745... |
Integration of adenovirus type 2 DNA in productively infected cells: results of sequential hybridization experiments. | In human KB cells permissively infected with adenovirus type 2, the high mol. wt. forms of virus DNA have been characterized. These size classes of virus DNA sediment at greater than 100S and 40 to 90S in alkaline sucrose density gradients. Considerable evidence from a series of earlier communications supports the noti... | 650,178 | [
-0.2912906,
0.07843474,
-0.04013256,
0.1035019,
0.197678,
-0.105176,
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0.1667385,
0.1733019,
0.1288143,
0.02245992,
-0.2876717,
-0.09417449,
-0.2091057,
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-0.3546039,
0.01586313,
-0.02741744,
0.1016018,
0.5766432,
-0.1237425,
-0.2200371,
... |
Minnesota Multiphasic Personality Inventory prediction of intellectual changes following cardiac surgery. | One hundred two cardiac surgery patients were tested with the Minnesota Multiphasic Personality Inventory (MMPI) preoperatively and 98 of these patientts (two diet, two were untestable) were tested both pre- and postoperatively with the Wechsler Adult Intelligence Scale, Bender-Gestalt, and the Wechsler Memory Scale. A... | 650,188 | [
-0.1002244,
0.1657634,
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-0.1359871,
0.01328389,
0.1173783,
0.01835905,
0.7273929,
0.5590477,
-0.08209286,
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0.4152775,
-0.4226693,
0.6059021,
-0.3554761,
-0.06852457,
-0.04634445,
0.1422505,
0.03028606,
... |
Social adjustment by self-report in a community sample and in psychiatric outpatients. | Data are presented on social functioning derived from a self-report social adjustment scale (SAS-SR) administered to 774 subjects including a community sample and three psychiatric outpatient populations: acute depressives, alcoholics, and schizophrenics. This self-report scale derives from an interview form and was de... | 650,195 | [
-0.1441044,
-0.2101939,
-0.07085281,
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0.1001955,
-0.0428477,
-0.2116897,
0.08465157,
0.00712897,
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0.04391017,
-0.07191948,
-0.1043731,
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-0.2192348,
-0.3654377,
-0.3261891,
0.4667482,
-0.127648,
0.006693923,
-0.227957,
-0.09666289,
0.00771... |
An investigation of weights in the parents of anorexia nervosa patients. | Although large series studies of anorexia nervosa families have found a greater than expected occurrence of anorexia nervosa in family members, there are no reports of the anorectic's parents' weights during the time of the patient's illness. An unusual degree of weight aberrations present in the parents at the time of... | 650,200 | [
-0.02481367,
0.1312153,
-0.1374032,
0.2904665,
0.2039211,
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0.05325995,
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0.2558301,
-0.05166715,
-0.3129617,
-0.2132262,
-0.2544518,
0.2628777,
-0.2040707,
0.07794667,
-0.1755766,
0.05220596,
-0.0828528,
0.04977058,
-0.2240788,... |
Diagnosis of subdural haematoma by computed axial tomography: use of xenon inhalation for contrast enhancement. | A subdural haematoma is described in which a definite computed tomographic (CT) scan diagnosis was made only after contrast enhancement had been achieved by the inhalation of xenon. The different types of enhancement obtained with iodide containing contrast media and with xenon are discussed. The use of xenon to obtain... | 650,246 | [
-0.3663988,
0.3014407,
-0.05842753,
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-0.04099371,
-0.1488891,
-0.3945835,
-0.2116648,
-0.1483998,
0.1638501,
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-0.09658784,
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0.06612916,
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0.2011569,
-0.06445639,
0.05800797,
0.1816988,
-0.03024402,
0.160599,
... |
Multivesicular bodies in cortical dendrites of two patients with Alzheimer's disease. | Biopsy fragments from the frontal cortex of 2 patients with Alzheimer's disease were studied with ultrastructural and cytochemical methods. A great number of light and dark, acid phosphatase positive, multivesicular bodies were observed in dendrites and their spines, in all cortical layers, being more abundant in layer... | 650,258 | [
0.06227705,
0.1412427,
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0.1002204,
0.07149088,
0.2424133,
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0.02372824,
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-0.09193619,
-0.3732715,
0.06903645,
-0.4961314,
-0.07628176,
0.4856317,
0.05946005,
0.4564431,
0.09571061,
-0.0320059... |
Schwann cell myelin ensheathing C.N.S. axons in the nerve fibre layer of the cat retina. | In the retina of the cat the axons of the nerve fibre layer are unmyelinated and are provided with a C.N.S. myelin sheath only in the extraocular part of the optic nerve. The present study demonstrates that in the apparently normal cat retina close to the optic disc, some axons of the nerve fibre layer run for a short ... | 650,264 | [
-0.4214768,
0.01238019,
-0.1779304,
-0.1486094,
-0.03106377,
-0.4092357,
0.006441434,
-0.05744735,
-0.0586205,
0.2556358,
-0.03598861,
0.1691425,
0.154009,
-0.2754421,
-0.08894176,
-0.3203041,
-0.6299383,
0.2672259,
0.08158495,
0.002296388,
-0.06957157,
0.2468229,
0.14657... |
Nerve cell degeneration and death in the trigeminal ganglion of the adult rat following peripheral nerve transection. | Trigeminal ganglia of normal rats and of adult rats subjected to unilateral transection of the infraorbital nerve were studied by light and electron microscopy. Counts of ganglion cells in ganglia on operated and unoperated sides were made following long postoperative survival times. The ultrastructural changes in gang... | 650,265 | [
0.1207198,
-0.0183427,
-0.1683436,
-0.138486,
-0.1641392,
-0.5674975,
0.07940303,
-0.08895399,
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-0.001019739,
-0.1648436,
-0.07465804,
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-0.2410256,
-0.6159943,
-0.02927163,
0.2443535,
-0.03298365,
0.01636692,
0.5184483,
0.2271... |
An intracellular analysis of some intrinsic factors controlling neural output from inferior mesenteric ganglion of guinea pigs. | 1. In vitro studies were conducted on neurons within the inferior mesenteric ganglion (IMG) of guinea pigs to investigate how intrinsic features of the spike-generating process interact with preganglionic inputs to produce the output firing patterns of these neurons. Intracellular-electrode techniques were used to moni... | 650,269 | [
0.07135096,
-0.1042084,
-0.41485,
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0.2493287,
-0.3414854,
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0.3183808,
-0.3056735,
-0.122577,
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0.1878019,
-0.2244586,
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-0.7754,
0.03753311,
0.0005107846,
0.2122086,
0.4301569,
0.09256352,
0.3348634,
0.11... |
Sustained depolarizing potentials in reticulospinal axons during evoked seizure activity in lamprey spinal cord. | 1. Intracellular recordings were made from lamprey reticulospinal axons (Müller axons) during seizures evoked by electrical stimulation of the isolated spinal cord in saline containing either 0 Cl or 1 mM picrotoxin. The seizures had tonic and clonic-phases similar to ictal seizures in mammalian brain. 2. During seizur... | 650,273 | [
-0.01494278,
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-0.3094853,
0.08051029,
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0.05730614,
0.09198468,
0.2498512,
0.1697903,
0.04669596,
0.1342945,
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-0.6593946,
0.4074774,
-0.08285212,
0.05487628,
0.1430028,
-0.05928733,
0.3485942... |
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