title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Relationship between theophylline-induced relaxation and excitation-contraction coupling in intestinal smooth muscle. | The effects of 1.0 to 10.0 mM theophylline on excitation-contraction (E-C) coupling in the taenia coli of the guinea-pig were observed with the sucrose-gap technique. Theophylline at all concentrations simultaneously inhibited spontaneous, calcium-dependent action potentials and muscle contractions. At the higher doses... | 677,956 | [
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Association between acute pancreatitis and malignant hypertension with renal failure. | Of 42 patients with malignant hypertension seen in five years in our institutions, seven (17%) had acute pancreatitis. All patients with pancreatitis were black, all had renal failure, and six received dialysis. No particular drug was received by all patients, gallstones were excluded in the majority, and alcoholism wa... | 677,980 | [
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Partial hypopituitarism following septic peritonitis with shock. | A 46-year-old man had a prolonged septic peritonitis with shock that resulted from a perforated appendix at the age of 29, followed, six months later, by the gradual development of partial hypopituitarism. Radiographic studies, including a pneumoencephalogram, did not reveal any evidence of sellar or surprasellar masse... | 677,985 | [
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Mutants of Alcaligenes eutrophus defective in autotrophic metabolism. | Forty-four mutants of Alcaligenes eutrophus H 16 were isolated which grew poorly or not at all under autotrophic conditions. Four types were characterized with respect to their defects and their physiological properties. One mutant lacked both enzymes specific for autotrophic CO2 fixation, another one lacked both hydro... | 678,018 | [
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Fungal transformation of naphthalene. | Eighty-six species of fungi belonging to sixty-four genera were examined for their ability to metabolize naphthalene. Analysis by thin-layer and high pressure liquid chromatography revealed that naphthalene metabolism occurred in forty-seven species belonging to thirty-four genera from the major fungal taxa. All organi... | 678,019 | [
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A comparative analysis of extreme thermophilic bacteria belonging to the genus Thermus. | Several extreme thermophilic Gram negative bacteria found in a thermally polluted river in Belgium have been compared with Thermus strains isolated from widely distant geographical areas. This analysis has become possible after the design of a new culture medium (162). All strains examined (including the isolate succes... | 678,024 | [
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[Cerebral trauma - psychological trauma? Study of 47 children with medulloblastoma and their follow-up]. | 47 Children with medulloblastoma who were treated between 1954 and 1974 were studied. The parents and children were interviewed regularly with their medical attendants to estimate the contribution of the organic disease, the psychological factors and the environment on their intellectual performance and their personali... | 678,035 | [
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A diagnostic interview: the schedule for affective disorders and schizophrenia. | The Schedule for Affective Disorders and Schizophrenia (SADS) was developed to reduce information variance in both the descriptive and diagnostic evaluation of a subject. The SADS is unique among rating scales in that it provides for (1) a detailed description of the features of the current episodes of illness when the... | 678,037 | [
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[Long-term follow-up study of the absorption of gas after encephalography in dilated intracranial cerebrospinal fluid spaces (author's transl)]. | The absorption of gas after encephalography in different groups of patients was investigated in a long-term follow-up study. Group I (11 patients) showed no pathological findings in the encephalogram. Group II (8 patients) had encephalographic signs of diffuse cerebral atrophy. Group III (7 patients) demonstrated in th... | 678,082 | [
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Adverse effects of calcium administration. Report of two cases. | Calcium chloride, 7 mg/kg, and calcium gluconate, 20 mg/kg, were administered to patients with low or low-normal levels of serum ionized calcium. Both patients had low blood pressure and cardiac index, and did not respond to digitalis, volume expansion, and beta-adrenergic stimulation with dopamine. Administration of c... | 678,101 | [
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[Excessive iron administration to sheep. 2. The effect on the iron, copper, zinc and manganese level in different organs]. | Lambs received 250, 1000 and 1750 mg Fe per kg concentrate dry matter. The Fe-supplementations caused the Fe-levels of spleen, liver, kidneys and ribs to rise significantly. Liver and spleen reflected most markedly the high Fe-supply. The Fe-supplementation reduced the Cu-content in the liver and the share of Zn in the... | 678,118 | [
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[Structure and function of the external part of the articular cartilage]. | The data on electron microscopic studies of the main structural elements of the superficial layer of the articular cartilage are represented. The articular cartilage of the femoral lead in young rabbits has been studied. The articular cartilage has no ideal smooth surface but three are some pressings of different sizes... | 678,128 | [
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[Effect of simultaneous administration of estradiol and progesterone on the proliferative pool of the uterine and vaginal epithelium in castrated rats]. | By the method of autoradiography, the proliferative pool in the epithelia covering the vagina, uterine body and its glands was investigated in ovariectomized rats treated with oestradiol alone and in combination with progesterone, under repeated injections of 3H-thymedine for 24 h. None of the epithelia studied demonst... | 678,129 | [
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[Ultrastructure of duodenal endocrine cells in children]. | All ultrastructural varieties of endocrine cells, described in literature for adult persons, were revealed in the epithelium of the duodenal crypts of children at the age of 6--14 years. The cells form rather distinct groups in accordance with the International Classification, that speaks in favour of adequate applicat... | 678,139 | [
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[Inverted papilloma of the bladder]. | No more than 40 cases of inverted papilloma (IP) of the urinary bladder have been reported in literature. The author presents 2 observations of IP in both of which the epithelial transitional cellular structures showed submerged pseudoinvasive growth and a peculiar inversion of the villous strucure. The tumor is benign... | 678,157 | [
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Retinal detachment due to ocular penetration. I. Clinical characteristics and surgical results. | The records of 74 patients--young and almost exclusively males--with retinal detachment due to ocular penetration were reviewed to study the characteristics and surgical results of this type of traumatic retinal detachment. There was a high incidence of industrial and domestic accidents. The incidence and degree of myo... | 678,171 | [
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Fluorescein iris angiography. II. Disturbances in iris circulation following strabismus operation on the various recti. | Iris circulation was investigated by fluorescein iris angiography in 33 human eyes before and after tenotomy of one or more recti for correction of strabismus. Tenotomy of one or both horizontal recti produced no appreciable circulatory disturbance in the iris, but tenotomy of superior or inferior rectus produced circu... | 678,178 | [
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Prosthetic functional therapy. A new method for rehabilitation of the orally handicapped patient. | A new approach to the rehabilitation of individuals who are orally handicapped after surgery offers direct support to dysfunctioning oral musculature, as well as physiologic conditioning to redirect tongue posture. Prosthetic functional therapy can be used to improve problems of speech, swallowing, drooling, and mastic... | 678,190 | [
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Bilateral choristomas of the external auditory canals. | To our knowledge, we report the first case of external auditory canal choristomas in the American literature. The pathologic condition of each side was serous salivary tissue, and at surgery, there was no connection with the parotid gland. | 678,195 | [
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Simultaneous bilateral parotid and submandibular gland calculi. | A recent review of the medical literature revealed no recorded cases of simultaneous bilateral parotid and submandibular calculi. We present such a case with roentgenographic documentation. | 678,196 | [
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Emergency mental health services during and after a major aircraft accident. | A major commercial aircraft accident mobilizes a sophisticated disaster response by the federal government and local disaster teams. However, there is no effort to deal with the significant mental health needs of survivors, airline crew, ground personnel, and rescuers. The time has come to deal with the human tragedy a... | 678,240 | [
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Effects of hypocapnia on psychomotor and intellectual performance. | Nine subjects performed five psychomotor tasks (two motor, two intellectual, and one combined motor and short-term memory) at three levels of PACO2 (38.5, 25.0 and 15.0 torr) with voluntary hyperventilation at 20 l/min. There were no performance decrements at PACO2 levels of 38.5 and 25.0 torr. At a PACO2 of 15.0 torr,... | 678,243 | [
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Changes in EEG pattern during acclimatization to high altitude (3500 m) in man. | This study was conducted on 30 healthy soldiers to observe EEG changes during acclimatization to high altitude. Of these subjects, 10 were lowlanders (LL), 10 were acclimatized low landers (AL), and 10 10 were high-altitude natives (HAN). The EEG was recorded by the 10-20 international system of electrode placement in ... | 678,248 | [
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Effects of hyperbaric oxygen and glutathione on mammalian liver metabolism. | The effects of hyperbaric oxygen tensions on oxygen consumption and succinate dehydrogenase (SDH) activity of mouse liver were investigated. Liver homogenates exposed to a PO2 of 3837 mm Hg for 30 min showed a 50.6% reduction in oxygen consumption compared to controls exposed to nitrogen at ambient pressure. The SDH ac... | 678,250 | [
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Mode of action of the lipid-lowering agents, clofibrate and BM 15075, on cholesterol biosynthesis in rat liver. | When rats were fed a diet containing 0.3% clofibrate or a derivative of this drug, BM 15075, serum cholesterol was lowered within 3-7 days by 26-38%. Both drugs diminished the activity of hydroxymethylglutaryl CoA reductase, the regulatory enzyme of hepatic cholesterol biosynthesis, in rat liver microsomes by about 60%... | 678,316 | [
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An interactional approach to dysfunctional silencing in family therapy. | This paper presents an interactional approach to the problem of dysfunctional silencing in family therapy. Silencing is classified as dysfunctional if it satisfies two conditions: (a) it occurs repeatedly and independently of content, and (b) it functions as negative feedback that limits change in the family system. Dy... | 678,353 | [
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Through the looking glass: the experiences of two family therapy trainees with live supervision. | A thorough investigation of the literature pertaining to therapy supervision reveals that supervision has never been examined from the viewpoint of the trainee. This paper examines live supervision of family therapy from that viewpoint. It suggests that live supervision is a powerful and effective tool--a tool that eng... | 678,354 | [
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Effects of fentanyl on intracranial pressure and cerebral perfusion pressure during hypocapnia. | Ten patients presenting for carniotomy were studied. Each was anaesthetized with thiopentone or Althesin followed by tubocurarine and the lungs were hyperventilated with nitrous oxide in oxygen. Fentanyl 0.2 mg was administered i.v. and the intracranial pressure (i.c.p.) and mean arterial pressure were recorded continu... | 678,364 | [
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0.08146138,
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-0.08225085,
0.2239373,
... |
Cardiac arrhythmia induced by pneumoencephalography. | Cardiovascular collapse associated with pneumoencephalography (PNE) has been reported but there has been no prospective study of its nature and cause. We have recorded prospectively the e.c.g. of 82 unselected patients, with no cardiovascular or metabolic disease, undergoing PNE under general anaesthesia. The frequency... | 678,372 | [
0.04543826,
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0.2353158,
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0.259519,
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Plasma protein binding of propranolol and isoprenaline in hyperthyroidism and hypothyroidism. | 1. The possibility that thyroid disease might result in alterations in the plasma proteins binding of drugs has been investigated by studying the binding of propranolol and isoprenaline in patients with hyperthyroidism and hypothyroidism. 2. Plasma protein binding of propranolol and isoprenaline has been measured in se... | 678,388 | [
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0.3139098,
0.02499789,
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0.3725552,
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A soft-agar procedure measuring growth of human colonic carcinomas. | Cell suspensions from 5 human colonic carcinomas were fractionated by velocity sedimentation and plated in soft agar. Cluster formation was restricted to the purest fraction of epithelial cells, as had been determined by immuno- and histochemical criteria. Plating efficiencies for the 5 specimens were 1.0-4.5%. The eff... | 678,422 | [
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0.5126372,
0.5057954,
0.1447843,
0.02278... |
Formylhydrazine carcinogenesis in mice. | Administration of 0.125% formylhydrazine in drinking water to 6-week-old randomly bred Swiss albino mice for life, induced lung tumours. Compared to untreated controls, the lung-tumour incidence rose from 15 to 94% in the females and from 22 to 100% in the males. The treatment had no detectable tumorigenic effect in ot... | 678,435 | [
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0.2397788,
0.2704689,
0.3199207,
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... |
The contributions of diet and childbearing to breast-cancer rates. | Mean, age-standardized breast-cancer mortality rates for women of 41 countries, during 1970-71, were closely correlated with diet for 1964-66. Partial correlation analysis indicated that breast-cancer rates were positively correlated with total fat, animal protein and animal calories, independently of other components ... | 678,437 | [
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0.02121666,
0.2070895,
0.2789484,
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0.16... |
Perineural angiogenesis in mice bearing subcutaneous tumours. | Cells of myeloma or fibrosarcoma were inoculated s.c. into BALB/c mice. Intact skins and tissue sections from animals killed at periodic intervals after inoculation of tumor cells were examined macroscopically and microscopically. The development of new blood vessels, probably involved in vascularization of the tumor, ... | 678,444 | [
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0.01306814,
0.1724656,
0.09423575,
0.02670303,
0.5047337,
0.254493,
0.3200894,
0.1051843... |
Induction of the acute-phase serum protein SAA requires both RNA and protein synthesis. | SAA is a normal acute-phase serum protein which has been identified by its cross-reaction with antibodies to the amyloid A fibril protein, AA, that is associated with secondary amyloidosis. The induction of SAA by bacterial lipopolysaccharide (LPS) has been studied with 3 inhibitors of protein synthesis: cycloheximide,... | 678,446 | [
-0.01897153,
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0.1318188,
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0.02640262,
0.4016023,
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0.1... |
Multiple naevocellular naevi in brothers with albinism. | Multiple naevocellular naevi occurring in two albino brothers are described. The light and electron microscopic findings of the naevi are described and the nature of the pigment discussed. | 678,455 | [
-0.1968385,
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0.07867301,
0.1511884,
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0... |
Pulmonary ventilation in pregnancy. | Serial tests of ventilatory function were made in 38 normal primigravidae during and after pregnancy. During pregnancy all patients showed major changes in tidal volume, functional residual capacity and residual volume. Minor changes were found in many other measurements, all of which occurred at an early stage of preg... | 678,486 | [
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0.1199766,
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... |
Dural arteriovenous fistula and spontaneous choroidal detachment: new cause of an old disease. | A case is presented in which bilateral spontaneous choroidal detachments appear to be the direce result of bilateral dural arteriovenous fistula of the cavernous sinus region. Rapid resolution of the clinical signs followed bilateral orbital decompression via the transfrontal approach. Similarities in clinical presenta... | 678,504 | [
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0.04036047,
0.1066438,
-0.1... |
Sites of phosphorylation on pyruvate dehydrogenase from bovine kidney and heart. | The highly purfied pyruvate dehydrogenase complex (EC 1.2.4.1) and uncomplexed pyruvate dehydrogenase from bovine kidney and heart mitochondria were phosphorylated and inactivated with pyruvate dehydrogenase kinase and [gamma-32P]ATP. Tryptic digestion of the phosphorylated pyruvate dehydrogenase yielded three phosphop... | 678,513 | [
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0.1351812,
0.1881838,
0.3296204,
0.007322271,
-0.... |
Identification of the catalytic site of rat liver glutathione peroxidase as selenocysteine. | A procedure was developed to isolate 75Se-labeled rat liver glutathione peroxidase (glutathione:H2O2 oxidoreductase, EC 1.11.1.9) at 30--50% purity with 20--30% yields in 4--5 days. Using these preparations of glutathione peroxidase, the selenium moiety in the enzyme was identified as selenocysteine by derivatizing the... | 678,534 | [
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0.1651355,
0.2935966,
0.1993643,
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0.2218537,
-0.01923... |
[Role of nonspecific complex formation in protein-nucleic acid recognition]. | Combinatory mathematical model of equilibrium binding of recognising proteins to DNA has been considered. The expression for the ratio of specific and unspecific complex as the function of a number of nucleotides in DNA, a number of centers of recognition, concentration of recognising molecules and a code number have b... | 678,565 | [
0.1461054,
0.07976513,
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0.01006258,
0.1887811,
0.6007803,
0.009888841,
-0.1752292,
... |
[Mathematical model of neuronal adaptation taking into account the effect of calcium on membrane permeability to potassium ions]. | A model of the adaptive neurone was suggested to base on the effect of increasing the potassium permeability during the increasing the intracellular calcium concentration. Calcium accumulation occurs due to entrance of calcium ions into the cell in the course of the potential action development. Extent of influence of ... | 678,575 | [
-0.1622177,
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0.2991361,
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0.09128366,
0.05451264,
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0.3990725,
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0.1406246,
... |
[Model of local spectral description of images in the visual system]. | On the basis of experimental evidence presented earlier a model of local spectral analysis of the image performed by the complex receptive fields of the visual cortex has been proposed. An essential feature of the model is that the generalized piece-wise Fourier transform is performed not over the image luminance funct... | 678,579 | [
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0.3385676,
0.2583338,
-0.135531... |
[Protonophoric and uncoupling activity of water-soluble pea flavonols]. | In the experiments with artificial lipid membranes and mitochondria the watersoluble pea flavonols are demonstrated to possess weak protonophoric and uncoupling activities which correlate with each other. It is concluded that the mechanism of flavonol uncoupling activity is the same as for classical uncouplers. The res... | 678,582 | [
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0.005059997,
0.2334199,
0.07883589,
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Ultrastructure of the cells in the peripheral blood of human embryos at early gestational stages. | The presence of the different blood series in the peripheral blood of 10- to 18-week-old human embryos was followed by electron microscopy. It has been demonstrated that the earlier the stage of embryonic development, the more immature cells are found in the peripheral blood. This phenomenon may suggest migration of bl... | 678,600 | [
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0.2648119,
0.3391283,
0.3548443,
0.1205791,
... |
The effects of thyroid hormones on myelination in the developing rat brain. | Rats radiothyroidectomized 1 day after birth received daily subcutaneous injections of 1 microgram/10 g body weight of thyroxine (T4) or an equimolar amount of triiodothyroacetic acid (T3AC) from day 6 through day 25. The number of myelinated axons, myelinated axon area, and area of the myelin sheath in the corpus stri... | 678,604 | [
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0.08005515,
0.2771414,
0.1996661,
-... |
[Method of electron autoradiographic study of RNA synthesis in gastric gland cells]. | A method of electron microscope autoradiographic investigation of gastric mucosa pieces obtained by clinical gastrobiopsy and incubated with uridine-5H3 was suggested. Comparison of the preparations with electron microscope radioautographs prepared after the administration of uridine-5H3 into the organism and with the ... | 678,641 | [
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0.3999562,
0.5447223,
-0.0416761,
-0.0643... |
[Effect of preliminary neurosensitization of rats on the postnatal development of the cerebral cortex of the progeny]. | The author investigated the cerebral cortex of 30-day ratlings born of rats preliminarily neurosensitized with a homologous cerebral cortex antigen, and of intact, control rats. In comparison with control, there was a reduction of the width of the sensory-motor region of the cortex, chiefly on account of the lower laye... | 678,662 | [
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0.2589628,
0.1220878,
0.2226941,
0.03178253,
... |
Membrane mechanical properties of ATP-depleted human erythrocytes. | Although the relations between the metabolic state and the mechanical properties of human red blood cells (RBC) continue to be of current interest, literature reports in this area are not in agreement. The present investigation was designed to determine several intrinsic mechanical properties of human RBC membranes bef... | 678,667 | [
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0.05866178,
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0.2077527,
0.6235904,
-0.04622529,
-0.0792035... |
Chronic lymphocytic leukemia (CLL) terminating in multiple myeloma: report of two cases. | Two cases of multiple myeloma (MM) developed late in the course of chronic lymphocytic leukemia (CLL). An 81-yr-old white female developed, after 6 yr of CLL, IgAk MM with sheets of plasma cells abutting sheets of lymphocytes in the bone marrow, multiple pathologic fractures, and 0.26 g/24 free k light chains in the ur... | 678,669 | [
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0.4282167,
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0... |
Effect of acute alcohol intoxication on granulocyte mobilization and kinetics. | Granulocyte mobilization into skin abrasions in human volunteers was significantly inhibited by acute alcohol intoxication (45,-800 cells in 8 hr versus 353,000 in normal controls). Alcohol applied locally did not inhibit granulocyte delivery, and protection of the abrasion against heat loss did not reduce the inhibite... | 678,671 | [
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-0.4107603,
-0.236238,
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0.2184978,
0.3050732,
0.1665858,
-0.0034869... |
Comparison of intracellular bactericidal activities of human neutrophils and eosinophils. | Eosinophils from a patient with hypereosinophilia were observed to phagocytize radiolabeled E. coli or S. aureus as effectively as neutrophils from a normal control. This was observed at a number of bacteria/cell ratios and a various time intervals following initial challenge and was confirmed by direct microscopic exa... | 678,676 | [
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0.03260454,
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0.3613481,
0.2390511,
... |
The spreading of leukocytes released from their liquid environment. | It is known that while leukocytes in conventional blood smears reveal their structures, in smears of erythrocyte-free suspension (EFS) they show a tendency to pyknosis. From the present study it appears that: 1. When any leukocyte suspension is subjected to drying on slides the cells undergo shrinkage (pyknosis in stai... | 678,682 | [
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... |
Influence of hen dietary calcium and phosphorus on the integrity of the egg shell as it would influence hatching success and the consequences of preincubation 2, 4, 5-T spraying with and without a high TCDD level. | Commercial strain laying hens were fed practical rations deficient in calcium and/or phosphorus to affect weak shelled eggs. Spraying these eggs prior to incubation with 2, 4, 5-T preparations having extremes in TCDD contamination at 10x recommendation was without effect on all parameters used to evaluate embryological... | 678,683 | [
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0.1489467,
0.2129598,
0.4521912,
-0.04538204,
... |
Toxic responses in gerbils treated topically with aflatoxin B1 and dimethylformamide. | Male and female Mongolian gerbils failed to show observable pathological responses in the liver to topically applied AFB1 and DMF indicating that percutaneous absorption of AFB1 is absent in this species. In males, some responses in weight changes were attributed, proportionally, to increased doses of DMF. Unexplained ... | 678,689 | [
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0.03111654,
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0.1736516,
-0.2043425... |
Clinical laboratory abnormalities and their follow-up in a mental hygiene clinic. | In a retrospective study, there were clearly abnormal laboratory findings in 4.8 per cent of 4,994 adults who attended for psychiatric evaluation at a mental hygiene clinic. In particular high fasting blood sugars, abnormal blood counts, eosinophilia, VDRL and abnormalities of chest X-ray or urinalysis were found. Just... | 678,738 | [
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0.1602122,
-0.2317916,... |
The hip joint in Paget's disease (Paget's "coxopathy"). | Three hundred patients with Paget's disease around the hip joint are compared with 300 control patients who did not have Paget's disease. The incidence of joint degeneration in the two groups is similar at all ages, and there appears to be no predisposition to joint degeneration in patients who have Paget's disease. A ... | 678,749 | [
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0.5372393,
0.1092336,
0.02040609,
0.05... |
Non-operative treatment of retained bile duct calculi in patients with an indwelling T tube. | The results of combined instrumental and chemical treatment of retained bile duct calculi in 18 patients with an indwelling T tube are reported. The instrumental extraction of stones was carried out through the T tube channel using a modified Dormia apparatus. The chemical method involved continuous infusion through th... | 678,775 | [
0.1019825,
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0.3368334,
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0.1588567,
0.3... |
Measurement of capillary blood glucose in filter-paper spots: an aid to the assessment of diabetic control. | A method of measuring glucose in capillary blood spotted on to filter paper was evaluated. Between-batch reproducibility was about 6%, and the glucose remained stable in the spots for up to four days. Adoption of the method should improve control of diabetes, particularly insulin-dependent forms. | 678,925 | [
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0.06846447,
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0.0311381... |
Protein and enzyme distribution in microsomal and myelin fractions from rat and Jimpy mouse brain. | The protein, glycoprotein and enzyme composition of myelin and myelin-related fraction (SN 4) from rat forebrain was compared with that of microsomal fractions. Acetylcholinesterase was largely confined to the microsomal fractions, wheras 2',3'-cyclic nucleotide-3'-phosphohydrolase (CNP) showed a high specific activity... | 678,972 | [
-0.05947572,
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0.1599914,
0.012929... |
Neuronal differentiation in somatosensory cortex of the rat. I. Relationship to synaptogenesis in the first postnatal week. | Newborn (P-0 and P-1) through 6-day-old (P-6) rats were studied using light microscopic (Golgi) and ultrastructural methods. Previous studies demonstrated that early-formed synapses are concentrated at specific cortical depths, i.e. in strata. The present study shows that the synaptic stratum in the marginal zone corre... | 678,985 | [
0.2351254,
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0.01287208,
0.2685966,
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0.1181403,
0.0... |
The influence of brain damage on locomotor behavior of mice selectively bred for high or low activity in the open field. | Locomotor activity was measured in mice with lesions restricted to the neocortex, in animals with hippocampal damage, and in sham-operated control mice of the selectively bred high and low open-field activity lines developed by J. C. DeFries. Postoperatively, the high-activity animals with hippocampal lesions showed re... | 678,991 | [
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0.1441506,
0.08639917,
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0.127921... |
Electron microscopic autoradiography of the uptake of [3H]GABA in dispersed cell cultures of rat cerebellums. I. The morphology of the GABAergic synapse. | Dispersed cell cultures of rat cerebellums 21 days in vitro were incubated in saline containing 0.5 micrometer [3H]GABA for 5 min, fixed and prepared for electron microscopic autoradiography. Quantitative methods for analyzing the resulting autoradiographs were developed to distinguish lightly labeled neurons from heav... | 678,997 | [
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0.249356,
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Uptake of L-alanine, glycine and L-serine in the pigeon central nervous system. | The uptake characteristics of L-alpha-alanine, glycine and L-serine into crude mitochondrial fractions from pigeon telencephalon, tectum and spinal cord were determined. Sodium dependent high affinity uptake systems were found for all 3 amino acids in all 3 brain regions, except for glycine in the telencephalon. The mu... | 679,019 | [
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0.1977045,
0.1694119,
0.1674664,
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The effect of a single oral dose of nonprotein nitrogen from various sources on amino acid concentrations in the plasma and liver of the chick. | Broiler chicks were fed normally for 21 d, then starved overnight and given a single oral dose of an aqueous solution of diammonium hydrogen citrate (DAHC), triammonium citrate (TAC), ammonium lactate (AL) or urea equivalent to 24.76 mg N. Controls were given water. The concentrations of free amino acids in the plasma ... | 679,054 | [
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0.4038637,
0.3310715,
... |
Interrelationships between dietary concentrations of sodium, potassium and chloride in laying hens. | Twelve diets, representing the factorial combination of two concentrations of Cl- (0.8 and 1.4 g/kg), three concentrations of Na+ (0.5, 1.1 and 1.7 g/kg) and two concentrations of K+ (7 and 12 g/kg) were fed to groups of laying hens for 24 weeks and records taken of their productivity. Different concentrations of Na+, ... | 679,055 | [
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0.2073388,
0.2833172,
0.2061935,
0.09952... |
Studies on the avian shell gland during egg formation: the effect of acetazolamide on the composition of the mucosa. | The effect of acetazolamide, an inhibitor of carbonic anhydrase activity, on the intracellular composition of the shell gland mucosa was determined. The normal cyclic hydration of the mucosal cells was found to be reduced when the egg was in the uterus and the partition of the water between the intra- and extracellular... | 679,057 | [
-0.274518,
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0.1242789,
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-0.07620324,
0.4120134,
-0.01367521,
-0.0938816... |
The effect of compounds which degrade hydrogen peroxide on the enumeration of heat-stressed cells of Salmonella senftenberg. | Greater than 90% of heat-stressed cells of Salmonella senftenberg failed to grow on trypticase soy agar. Adding to this medium compounds which are capable of degrading hydrogen peroxide allowed growth of the heat-injured cells. These compounds did not stimulate growth of heated cells of Streptococcus faecium, an organi... | 679,073 | [
-0.1357826,
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0.04925836,
0.05544777,
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0.05911443,
0.4966685,
0.4933239,
0.2287428,
-0.122230... |
Prinzmetal's angina, normal coronary arteries and pericarditis. | A woman with Prinzmetal's variant angina had spontaneous attacks of myocardial ischemia characterized by severe chest pain, hypotension, inferior ST-segment elevation, transient complete heart block and selective right ventricular dysfunction. Despite initial improvement following intravenous administration of atropine... | 679,098 | [
-0.2691475,
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0.2330666,
0.1243126,
-0.02859007... |
Carbon monoxide poisoning and nonoliguric acute renal failure. | Carbon monoxide poisoning in a 37-year-old man was complicated by neurologic damage, skin changes, muscle necrosis and nonoliguric renal failure. The relation between nontraumatic rhabdomyolysis and acute renal failure in carbon monoxide poisoning is reviewed. Recognition of the acute renal failure in such cases is imp... | 679,099 | [
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0.1516954,
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0.3031929,
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-0.... |
Air transport of infants in Newfoundland and Labrador. | Air transportation of 33 infants in small unpressurized aircraft over long distances is described. Twenty-six of the infants were transported more than 320 km in environmental temperatures varying from -35 to +21 degrees C. A commercially available incubator was used. Although more than half the infants had a rectal te... | 679,112 | [
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0.1948083,
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Primary extranodal lymphoma: response to treatment and factors influencing prognosis. | The cumulative 10 year lymphoma experience of a teaching hospital and two of its affiliated institutions was reviewed. From this group, a series of 39 cases of regionally localized primary extranodal lymphomas (Ann Arbor Stages IE and IIE) were selected for study. This group of patients was analyzed for response to ini... | 679,145 | [
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0.2920142,
0.2614989,
0.3157528,
0.2858998,
-0.2665104,
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LDH isoenzyme patterns in human gastric mucosa with precancerous changes. | By using an original method of electrophoresis separation, the normal relative values of each one of the LDH isoenzymes in the gastric body and antral mucosa were determined. It has been shown in gastric tumors that there is a significance rise in the relative values of "type M" isoenzymes (iso-LDH-4-5). With intestina... | 679,151 | [
-0.3591477,
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0.3483071,
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0.02664922,
0.05190585,
-0.1348584... |
Thin needle biopsy in the diagnosis of ureteral obstruction with malignancy. | Ureteral obstruction after treatment for abdominal cancers is a common situation in which the thin needle biopsy presents an attractive low morbidity alternative to laparotomy for the diagnosis of malignant disease. A negative biopsy is still nonconclusive, although helpful in determining the next step in the patient's... | 679,162 | [
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0.04934786,
-0.08817355,... |
The respiratory epithelium in the lungs of the slow-worm, Anguis fragilis. | The epithelium covering the respiratory portion in the lung of the slow-worm (Anguis fragilis) has been studied by electron microscopy. The epithelium is composed of two different types of pneumonocytes. The type I pneumonocytes are roughly squamous and their cytoplasmic sheets spread over relatively large areas of the... | 679,263 | [
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0.2840647,
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0.3278737,
0.3306969,
-0.21375... |
Effect of cyproterone acetate, d-norgestrel and progesterone on cells of the pars distalis of the adenohypophysis in the beagle bitch. | The effects of short-term (8 weeks) treatment with different doses of cyproterone acetate (CPA), d-norgestrel (d-N) and progesterone on cells of the pars distalis, as revealed by the immunoperoxidase technique, were studied in cycle-synchronized beagle bitches (first anoestrus). Pituitary glands from non-treated primip... | 679,265 | [
-0.07063279,
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0.2541794,
0.1255323,
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0.3170722,
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0.2118861,
0.0481807,
-... |
Fine structure of degenerating abdominal motor neurons after eclosion in the sphingid moth, Manduca sexta. | Ultrastructural aspects of the natural degeneration of a group of six motor neurons in the fourth abdominal ganglion of Manduca sexta are described. These motor neurons innervate intersegmental muscles that degenerate and disappear immediately after adult eclosion. The first detectable changes in the cell bodies appear... | 679,269 | [
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0.03681121,
0.1206735,
0.5582619,
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Diet and sire effects on serum cholesterol and cholesterol absorption in infant baboons (Papio cynocephalus). | One hundred three baboon infants, the progeny of an equal number of dams and seven sires, were breast fed or were fed prepared formulas containing 1.2, 29, or 61 mg/dl cholesterol for 14 weeks. We measured serum cholesterol and triglyceride concentrations at birth and at 3-week intervals, and cholesterol absorption at ... | 679,419 | [
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0.05719939,
0.1022287,
0.1347002,
0.2748664,
-0.06070... |
Pressor responses to norepinephrine in rabbits with 3-day and 30-day renal artery stenosis. The role of angiotensin II. | Pressor responses to norepinephrine (NE) infusions were examined in normal rabbits, in rabbits with renal artery stenosis of over 30 days' duration (chronic renal hypertensive rabbits), and in rabbits with renal artery stenosis of 3 days' duration (3-day clipped rabbits). The 3-day clipped rabbits did not have hyperten... | 679,426 | [
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0.376063,
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0.2864907,
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0.1787614,
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... |
Aortic input impedance in heart failure. | The input impedance of the systemic circulation was calculated from recordings of pulsatile pressure and flow in the ascending aorta of 20 patients. Ten patients had clinical and hemodynamic evidence of heart failure. The other 10 subjects had no clinical evidence of heart failure and were used as a control group. In t... | 679,436 | [
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0.4499134,
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0.1808531,
0... |
Development and evaluation of a glucose analyzer for a glucose controlled insulin infusion system ((Biostator). | The Glucose-Controlled Insulin Infusion System (Biostator) is a modular, computerized, feedback control system for dynamic control of blood glucose concentrations in diabetics. This on-line glucose analyzer for use with whole blood utilizes a novel enzyme (glucose oxidase)-membrane configuration and an electrochemical ... | 679,460 | [
0.1308567,
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0.0334085,
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0.02763746,
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0.05669282,
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0.2167721,
0.2028279,
0.1114222,
-0.1255268,
... |
Infinite dilution conductimetry of plasma and urine: correlation with osmolality. | The infinite dilution conductivity (IDC) of plasma and urine allows a measurement of the electrolyte content in small samples (5 to 15 microliter). The method was compared to the corrected osmolality (II'p) measured by the freezing-point depression. A linear correlation existed between II'p and the IDC: for plasma: II'... | 679,486 | [
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0.1529505,
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0.03338464,
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0.106983,
-0.0335964,
-0.02382132,
0.08354485... |
Use of the Fogarty embolectomy catheter as an "internal tourniquet". | The Fogarty embolectomy catheter has been found useful in minimizing blood loss in large surgical procedures about the hip and pelvis. Its utility lies in the ability to achieve temporary intraluminal occlusion of the common iliac artery while the proposed surgical procedure is being carried out. The technique of instr... | 679,532 | [
-0.002958809,
0.4200195,
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0.2691392,
0.147371,
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0.002198083,
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0.1451908,
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-0.002004666,
-0.1522316,
-0.2395048,
-0.04944796,
-0.1199094,
-0.054399... |
Nontraumatic osteomyelitis of the patella. | Nontraumatic, hemotogenous osteomyelitis is a childhood disease uncommonly encountered and rare in the patella. The initial signs are usually intraarticular, because of the sterile effusion. The primary pathology in the patella is easy to overlook. The infection generally does not penetrate the joint cavity and most ca... | 679,536 | [
-0.2298709,
0.1042211,
0.1207124,
0.08147476,
-0.420138,
-0.4509372,
-0.4178683,
-0.01342954,
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-0.2682742,
0.4631675,
0.2265069,
0.08344944,
-0.1713048,
-0.1122639,
-0.03366615,
-0.3387533,
0.07714847,
-0.004103546,
-0.2667403,
0.2604867,
-0.1914429,
0.02123614... |
Problem areas in the diagnosis and treatment of ligament injuries of the knee. | The importance of the correct and early diagnosis of these soft tissue injuries to the knee cannot be overemphasized. There is a definite place for non-operative management of carefully selected patients. Realistic goals and expectations of surgery must be discussed with the patient to avoid postoperative misunderstand... | 679,542 | [
-0.1152906,
0.3520296,
-0.01432805,
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-0.2173973,
0.06837167,
-0.2399318,
-0.1829435,
0.1382653,
-0.2864679,
0.24622... |
A new power tool for removal of methylmethacrylate from the femur. | An air turbine drill will remove methylmethacrylate from the medullary canal of the proximal femur in cases of failed total hip replacement and from the distal femur in cases of failed long stem total knee replacement. This power tool is expensive, but the high cost is partially offset by multiple other uses: cutting b... | 679,552 | [
-0.08122691,
0.107779,
0.04431381,
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0.07130293,
-0.2848854,
-0.03105368,
0.2620335,
0.04013344,
0.091265... |
Effects of an oral contraceptive on hepatic size and antipyrine metabolism in premenopausal women. | Liver volume and antipyrine disposition have been investigated in healthy premenopausal women who received 30 microgram ethinyl oestradiol + 500 microgram dl-norgesterol as an oral contraceptive. Six months' treatment was associated with a 17% increase in liver volume while no change occurred in age-matched control sub... | 679,600 | [
-0.2260622,
0.2861178,
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0.02029734,
0.03141216,
0.2202333,
0.1146833,
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0.2728403,
-0.05002186,
0.3217374,
-0.05620605,
0.2436854,
0.0038671... |
The chest film findings in 'Q' fever--a series of 35 cases. | Thirty-five cases of 'Q' fever have been admitted and confirmed serologically over the past 20 years. Thirty-two of these cases had chest films on admission, and lung changes were present in 87%. The lung changes were: 1. Multiple round segmental consolidations, 5--10 cm in diameter, of ground glass density and usually... | 679,610 | [
-0.005022353,
0.3042725,
0.1690207,
-0.01446738,
-0.153324,
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0.00869007,
0.04287935,
0.3518377,
0.1337893,
0.012559,
0.3339599,
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0.114453,
0.07846662,
0.1097899,
0.4932854,
0.02793148,
-0.2924074,
-0.... |
Biphasic changes in thymus structure during evolving renal hypertension. | 1. Structural changes in the thymus during the evolution experimental renal hypertension were investigated to determine their possible role in the genesis of hypertensive vascular disease. 2. The thymus, adrenal glands and the progression of hypertensive vascular lesions were investigated in rats during the first 30 da... | 679,625 | [
0.09225088,
0.06077218,
-0.4277578,
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0.1049237,
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0.1270132,
0.1383725,
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0.22383,
0.2685231,
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0.06494453,
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0.2733203,
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-0.08642327,
0.1190762,
0.1449617,
0.1585241,
0.3922922,
-0.05885244,
... |
Hemisphere differences in the recognition of nonsense shapes: cerebral dominance or strategy effects? | A tachistoscopic visual half-field task involving delayed recognition of nonsense shapes did not prove to rely disproportionately on either cerebral hemisphere. However, subjects at either extreme of the laterality distribution were more accurate at recognition overall, relative to subjects displaying indeterminate lat... | 679,705 | [
-0.02826258,
0.289126,
-0.344845,
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0.2872343,
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0.2198802,
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0.04420158,
0.3016549,
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0.008611051,
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-0.4328466,
-0.02833144,
-0.1434618,
-0.1738241,
0.3319745,
0.3812912,
-0.06110649... |
Ageing of the female gamete. 2 Lactate dehydrogenase activity in fragmented oocytes and ova of the rat. | LDH enzyme activities were determined in atretic and fragmented oocytes. The enzymatic activities in fragmented oocytes and ova were compared to those already known in early rat cleavage stages. Atretic oocytes are totally devoid of LDH activity. However, fragmented oocytes and ova exhibit nearly identical LDH activiti... | 679,722 | [
0.1484016,
-0.2111846,
-0.1338468,
0.1283298,
0.1647092,
-0.4155238,
0.279111,
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0.08695714,
0.202844,
0.1177604,
0.3595773,
0.09057754,
0.09263013,
-0.1962676,
0.08617838,
-0.7877118,
-0.004453548,
0.2577531,
0.002373491,
0.3062987,
0.2429262,
-0.1949213,
0... |
Interaction of microtubules and the mechanism of chromosome movement (zipper hypothesis). 3 Theoretical analysis of energy requirements and computer simulation of chromosome movement. | A theoretical analysis of the energy requirements and a computer analysis of a special case (symmetrical pull in one plane during anaphase), of the zipper model for chromosome movement (Bajer, 1973a,b) is presented. The conclusions are general, however, and can be applied to any stage of mitosis. It is assumed that the... | 679,724 | [
0.2042044,
-0.06136144,
-0.1188537,
0.03631368,
0.1705098,
-0.1052958,
-0.3187388,
-0.01397695,
0.1291189,
0.02271562,
-0.07315625,
-0.1396082,
-0.3032963,
0.3873835,
-0.5928484,
0.02045366,
-0.4410624,
0.2853762,
-0.003407432,
-0.06691675,
0.8277249,
0.06075662,
-0.10990... |
Legionnaires' disease. Clinical and pulmonary histopathologic features of a sporadic case. | The pulmonary histopathologic features in a sporadic case of Legionnaires' disease are shown. The changes include acute bronchitis with focal ulceration and diffuse acute interstitial pneumonitis. These changes are not those seen with typical bacterial pneumonia but are similar to changes seen when viruses, rickettsiae... | 679,758 | [
-0.2006144,
-0.1094918,
0.08935838,
-0.1976431,
0.03104454,
-0.1601503,
-0.2482316,
-0.2582557,
-0.2189218,
0.1965547,
0.3949055,
0.03427831,
-0.1472114,
0.2659904,
0.04067929,
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-0.1602883,
0.03932457,
0.2661484,
-0.1270076,
-0.081993,
-0.03130302,
0.01112877,
... |
Sex role concepts of two- and three-year-olds. | An instrument was developed to assess beliefs about males and females in very young children. Use of the instrument with 72 2- and 3-year-old subjects indicated that children as young as 2 years of age possess substantial knowledge of sex role stereotypes prevailing in the adult culture. Knowledge of sex role stereotyp... | 679,779 | [
-0.09378978,
0.08580451,
-0.1820873,
-0.2137776,
0.3561135,
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-0.06922638,
-0.004626535,
0.08525146,
-0.1144298,
0.1132164,
0.20545,
-0.2777769,
-0.2085226,
-0.457805,
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-0.05938805,
0.2478499,
-0.5103371,
0.09523441,
0.5362242,
0.2140361,
-0.2139179,
... |
[Choice of procedure in the surgical treatment of liver injuries]. | We give an analysis of liver-rupture cases among our own patients and discuss the problems of diagnosis and surgical therapy. Total lethality is 29%; this is dependent on quick diagnostic procedure, the number and severity of accompanying traumas, and the type of liver rupture. The main diagnostic feature seems to be p... | 679,788 | [
-0.06859721,
0.03662242,
-0.1081568,
-0.1076696,
0.07379449,
-0.2633186,
-0.1593003,
-0.3448425,
0.01517416,
0.1062691,
0.2141343,
-0.06497212,
0.0153226,
-0.1074721,
-0.3788105,
-0.2455143,
-0.2302114,
0.2209085,
0.0480713,
0.2664601,
0.2601528,
-0.0134612,
0.009529622,
... |
Severe asthma: prevention is better than cure. | Asthmatic patients during sympton-free periods almost invariably have abnormalities in lung mechanics and gas exchange. Tentacious secretions and mucosal thickening exaggerate maldistribution of ventilation and cause flow limitation in small airways. Hence, the maximal expiratory flow volume loop in these patients will... | 679,860 | [
-0.04415479,
-0.06955235,
-0.1654598,
0.02511227,
0.0389905,
-0.1234726,
-0.1826737,
-0.2537006,
0.3334313,
-0.4423056,
0.03922184,
-0.2929655,
-0.2588966,
0.1559737,
-0.2708082,
0.04044924,
-0.1650886,
-0.1775623,
-0.09102199,
-0.0118796,
0.09604201,
-0.01287271,
-0.1538... |
Effect of glucose on plasma glucagon and free fatty acids during prolonged exercise. | The effects of glucose ingestion on the changes in blood glucose, FFA, insulin and glucagon levels induced by a prolonged exercise at about 50% of maximal oxygen uptake were investigated. Healthy volunteers were submitted to the following procedures: 1. a control test at rest consisting of the ingestion of 100 g glucos... | 679,944 | [
-0.2726731,
0.2048966,
-0.3819804,
-0.2079031,
0.2432951,
-0.1578737,
-0.1201341,
0.07665901,
-0.1826923,
-0.09286759,
0.1660377,
-0.01316729,
-0.2422068,
-0.3938642,
-0.2507322,
-0.3204879,
-0.2828325,
0.2729945,
0.01103961,
0.0391698,
-0.1038922,
0.08424352,
0.1037701,
... |
Pituitary function in a patient with septo-optic dysplasia and pituitary dwarfism (Kaplan-Grumbach-Hoyt syndrome). | The cause of a seventeen-year-old female patient with septo-optic dysplasia and pituitary dwarfism is presented. Mental retardatin and epilepsy, in addition to absence of the septum pellucidum, point to a widespread lesion of the central nervous system. There is unilateral hypoplasia of the optic nerve. She is of small... | 679,955 | [
0.05211585,
-0.3882349,
-0.2145827,
-0.3669604,
-0.01279494,
-0.3738957,
-0.06793076,
-0.2296538,
-0.01286157,
0.21024,
0.07591549,
0.3013711,
-0.006463168,
0.3322177,
0.1052703,
-0.03541409,
-0.3639889,
0.2130265,
0.1255875,
-0.06932967,
-0.1904483,
0.2416518,
-0.0740506... |
Anatomy of the naso-lacrimal duct in new-borns: therapeutic considerations. | The topography and morphology of the lacrimal ducts in newborn infants was demonstrated by means of post mortem dacryocystograms and microphotograms of histologic slides. Because of bends in the course of the lower tear duct, a percentage of probings will fail to effect satisfactory perforation of the Hasner membrane. ... | 679,960 | [
0.1306613,
0.1374982,
-0.2131731,
0.1299838,
-0.04916037,
-0.2280032,
-0.2860913,
-0.1754076,
0.8081805,
0.147563,
0.4340047,
-0.1958441,
-0.2348215,
-0.2462468,
-0.4372471,
-0.183803,
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0.2788142,
0.1300965,
-0.3181819,
0.2283862,
0.1050482,
-0.1407004,
0.073... |
Exocrine secretion of canine pancreas perfused extracorporeally. | A canine gastroduodenopancreatic block was isolated and perfused extracorporeally with homologous blood. This preparation was used for studying stimulated exocrine secretion of the pancreas. Stimulants were infused intra-arterially. Both vagi were stimulated electrically. Hydrochloric acid or L-phenylalanine were insti... | 679,962 | [
0.01512537,
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-0.4293077,
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-0.03362862,
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-0.02238732,
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-0.2761759,
0.2086405,
0.2004945,
0.2585068,
-0.213865,
-0.3472365,
-0.03076647,
-0.09662196,
-0.2154648,
0.2289354,
-0.002814513,
-0.05218641,
-0.178197,
0.09316298,
0.14361... |
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