title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Anomalous muscle bundle of the right ventricle. Its recognition and surgical treatment. | This communication presents our experience with 14 cases of congenital heart disease associated with anomalous muscle bundle inside the right ventricular cavity dividing it into two chambers. The clinical picture, natural history, and diagnostic characteristics are described. It can be diagnosed by right ventricular ci... | 708,529 | [
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The diagnosis of a non-stenotic bicuspid aortic valve. | Follow-up of a group of subjects in whom an aortic ejection sound was the only abnormal finding revealed a bicuspid aortic valve at necropsy or operation in 6 cases. High speed echophonocardiographic studies in 15 subjects with aortic stenosis and known to have bicuspid valves, showed the ejection sound to be exactly s... | 708,534 | [
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Diagnosis of coronary artery disease by estimation of coronary sinus lactate. | In an attempt to assess the value of coronary sinus lactate estimation before and during atrial pacing for the diagnosis of obstructive coronary artery disease, 70 patients with angina were investigated in this way and by selective coronary arteriography. Thirty-five had radiologically normal coronary arteries and 35 h... | 708,539 | [
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Effect of thiamylal on the sensitivity of glycerinated cardiac fibres to calcium. | Clarification of the mechanisms of the myocardial depression produced by thiamylal was sought by studying the effect of thiamylal upon the sensitivity of contractile proteins to calcium (Ca2+), by using glycerinated muscle fibres from the canine right ventricle. The dose--response relationship between the concentration... | 708,554 | [
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Effects of age and sex on ketamine anaesthesia in the rat. | Intraperitoneal injections of ketamine 75 mg kg-1 in rats of both sexes (age 1--16 weeks) revealed a significant relationship between increased age and decreased duration of sleeping time for both sexes during the first 3 weeks of age. This decrease in sleeping time seemed to be associated with the increased production... | 708,555 | [
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Frequency of previous anaesthesia in an anaesthetic patient population. | Ten thousand patients presenting for anaesthesia were questioned about their anaesthetic history; 6672 had received an anaesthetic previously, 19.2% in the preceding 4 weeks. Of 2780 in whom the agents were known, 80.4% had received thiopentone, 18.1% Althesin and 57.4% halothane. Thirty-seven per cent of the total sur... | 708,559 | [
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Plasmapheresis and plasma cholinesterase. | Plasma cholinesterase (E.C. 3.1.1.8) concentrations were measured in nine outpatients who were undergoing regular plasmapheresis. A single plasmapheresis produced a 64% reduction in cholinesterase concentration compared with the value before plasmaphersis. Another patient who received four plasma exchanges in 6 days sh... | 708,562 | [
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Bone-metastasizing renal tumour of childhood. | A primary renal tumour of childhood with histological appearances different from the nephroblastoma is described. This neoplasm, predominantly seen in boys, has a tendency to metastasize to bone. Such metastases are considered to be rare in nephroblastoma and this aspect in studies of Wilms' tumour series is thought to... | 708,576 | [
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Leukocyte migration agarose test (LMAT) in sarcoidosis using Kveim test material. | The two-stage leukocyte migration agarose test (indirect LMAT), shown to be a sensitive in vitro assay for cell-mediated immunity, was used to study Kveim reactivity in vitro in patients with sarcoidosis. No Kveim-induced inhibition of leukocyte migration in agarose or Kveim-induced lymphocyte transformation in vitro w... | 708,592 | [
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Oral treatment of ichthyosis with an aromatic retinoid. | An aromatic retinoid (Ro-10/9359) was used for oral treatment of five cases of ichthyosis (three lamellar, two X-linked. Complete clearing of the skin lesions was achieved in all five patients within 24.2 +/- 3.2 days (X-linked 21.75 +/- 6.5, lamellar 23 days). Histopathology showed reduction of the hyperkeratosis, and... | 708,600 | [
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Ways of expressing results of human bone marrow progenitor cell culture. | In human bone marrow culture studies the number of granulocyte progenitor cells (CFUc) is expressed as the number of colonies per 10(5) incubated, nucleated cells. However, this provides little information on cell proliferation kinetics of granulopoiesis. The ratio of progenitors (CFUc) to end cells (metamyelocytes or ... | 708,635 | [
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Organelle pathology in primary and secondary haemochromatosis with special reference to lysosomal changes. | The organelle pathology of liver biopsy specimens from patients with either primary or secondary haemochromatosis was investigated by analytical subcellular fractionation in combination with enzymic microanalysis. The most striking changes were found in the lysosomes. Increased total activities but decreased latent act... | 708,644 | [
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Effects of maternal cigarette smoking on the fetus and placenta. | In a large, prospective study, mothers who smoked during one pregnancy but not another had smaller infants in the pregnancy in which they smoked, irrespective of birth order and many other factors that affect fetal growth. Light cigarette smokers gained an average 90 g less at term than non-smokers, entirely due to the... | 708,656 | [
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The effect of low haematocrit on serum human placental lactogen values. | Serial determinations of serum human placental lactogen (HPL) levels in women with haematocrit values of 28 per cent or less between 18 and 30 weeks gestation have been compared with the controls who had haematocrit values of 35 per cent or more. The women with low haematocrit values were found to have significantly ra... | 708,660 | [
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Effects of cigarette smoking on intraocular pressure and vision. | In a survey of 426 patients of Toronto ophthalmologists the correlations of reported smoking habits with (1) intraocular pressure and (2) visual acuity were examined. Average tonometer readings were closely similar in smokers, ex-smokers, and non-smokers, and multiple regression analysis showed similar age coefficients... | 708,669 | [
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Isolation of Chlamydia psittaci from a patient with interstitial keratitis and uveitis associated with otological and cardiovascular lesions. | A case history of a 15-year-old schoolgirl with fluctuating bilateral uveitis, bilateral stromal keratitis with vascularisation, and bilateral deafness associated with tinnitus and balance disturbance is described. Three years from the onset of her clinical signs she died of a sudden cardiac arrest caused by endocardit... | 708,673 | [
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Rapid, single-step purification of restriction endonucleases on cibacron blue F3GA-agarose. | After sonication and high-speed centrifugation, crude extracts of B. amyloliquefaciens, P. alcalifaciens, X. holicola, and B. globiggi were adsorbed on the dye Cibacron blue F3GA convalently cross-linked to agarose. The restriction endonucleases BamHI, PalI, XhoI, and BglI together with BglII were isolated by elution o... | 708,697 | [
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13C Nuclear magnetic resonance studies to the binding of isocyanides to various hemoglobins and myoglobins. | Interactions between ethyl and isopropyl isocyanides and various hemoglobins and myoglobins have been studied by 13C nuclear magnetic resonance. The results indicate that the chemical shift of the bound isocyanide depends on the structure of the hemoglobin subunit or myoglobin. The resonances exhibited by isocyanides b... | 708,715 | [
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Effect of magnesium on calcium efflux in dialyzed squid axon. | The Ca efflux mechanism located in the axolemma of the tropical squid Doritheutis plei is shown to be affected by the concentration of intracellular Mg (Mgi). The removal of all of the Mg from the experimental preparation causes an increase in Ca efflux. This effect seems to be more pronounced at low levels of internal... | 708,729 | [
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Carnitine-induced uptake of L-cartinine into cells from an established cell line from human heart (CCL 27). | L-Carnitine is actively transported into Girardi human heart cells, an established cell line from human heart. The present study was undertaken to investigate the effect of different concentrations of L-Carnitine in the growth medium on the rate of uptake of L-[3H] carnitine. Increasing the concentration of L-Carnitine... | 708,732 | [
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Interaction studies of the 165 000 dalton protein component of the M-line with the S2 subfragment of myosin. | The M-line protein component of molecular weight 165 000 was isolated and purified from rabbit skeletal muscle using ion exchange chromatography. Sodium dodecyl sulphate electrophoresis revealed that the protein was homogeneous. Circular dichroism measurements indicated that the protein interacts with myosin and heavy ... | 708,756 | [
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Physiological response patterning in short--and long--term heart rate control training. | The present investigation assessed the physiological response patterns which accompany heart-rate control performance, both early and late in training. Six subjects were employed who received six heart-rate control training sessions, half of which were speeding sessions and half of which were slowing. Heart rate, skin ... | 708,812 | [
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Probing ultrafast biological processes by picosecond spectroscopy. | A brief discussion of the initial events leading to the visual transduction process will be presented to illustrate the capabilities of picosecond spectroscopy. | 708,835 | [
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Mass spectral studies on prostaglandins. V--Deuterated analogues of prostaglandin F2alpha. | In order to check the fragmentation mechanisms proposed in the preceding paper of this series the mass spectral behaviour of some deuterated analogues of prostaglandin F2alpha have been studied. In general, the investigation of these compounds confirmed the previous assumptions and shed light on some further details of... | 708,857 | [
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[Activity in the myelinated fibers of a cat cutaneous nerve in response to cooling]. | The afferent activation in cat cutaneous nerve fibres in response to cooling was analyzed using the collision method and the method improving the signal-to-noise ratio in the antidromic action potential neurogram. It was found that the nerve fibres of groups Adelta1 and Adelta2 were activated under cutaneous receptors ... | 708,863 | [
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[Experimental analysis of the humoral mechanism of microcirculatory disorders following thermal and mechanical traumatic shock in experiments on parabiotic rats]. | In experiments on parabiotic rats with crossed circulation and separate innervation mechanical or burn trauma of one of the partners was followed by shock-like condition of the other one, and by microcirculatory changes in the mesentery typical of burn or traumatic shock. It shows that in burn shock, as well as in trau... | 708,867 | [
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[Effect of cerebral ischemia on the metabolism of individual lipid fractions]. | Ninety minutes after ligation of common carotid arteries a decrease of the metabolism intensity both of the total phospholipids (PL) and of their different fractions was nearly the same. In the diencephalon reduction of the metabolic rate of the total PL was accounted for by metabolic depression of phosphatidylcholine ... | 708,868 | [
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[Effect of several extreme influences on the submicroscopic organization of rat liver following carbon tetrachloride poisoning]. | Submicroscopic structure of parenchymatous cells was investigated in the liver of rats given CCL4 (0.12 ml/100 g body wt) for 25 days. After cessation of this treatment the animals were subjected to the action of extreme stimulants (immobilization or overheating under sunlight or both). CCL4 poisoning led to the appear... | 708,884 | [
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Management data for collection analysis and development. | Sound management data are needed to evaluate the collections of health sciences libraries. This study reports the utilization of computer data bases to compare the libary collections of The University of Texas Health Science Center at San Antonio. The University of Texas Medical Branch, and the National Library of Medi... | 708,955 | [
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The clinical librarian and the patient: report of a project at McMaster University Medical Centre. | In June 1975 a clinical librarian project was initiated in the Gastroenterology Programme of McMaster University Medical Centre. The objectives of the project were to assist patients in participating more knowledgeably in their own health care and to assist health professionals in applying the latest information from b... | 708,957 | [
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Demonstration of 5-hydroxytryptamine receptors through inhibition by methergoline in cat pial arteries in vitro. | 1 In an attempt to characterize further the nature of the 5-hydroxytryptamine (5-HT)-induced contraction of intracranial vessels, cat's middle cerebral artery was exposed to this amine and the specific 5-HT receptor antagonist, methergoline, under standardized conditions in vitro. Methergoline, in increasing concentrat... | 708,997 | [
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Effects of somatostatin on gastric acid secretion and on lipid and carbohydrate metabolism in the rat. | 1 Studies were conducted to examine the effects of somatostatin on pentagastrin-induced gastric acid secretion, and on bile, plasma and liver lipid composition in the rat. 2 In addition, liver glycogen and plasma glucose concentrations were measured. 3 Somatostatin was administered intravenously as a bolus (100 microgr... | 709,001 | [
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Obstetric care in the central Canadian Arctic. | All pregnancies that occurred during 1971-5 among 4000 Canadian Eskimos living in isolated settlements in a district of the North-west Territories were reviewed. Obstetric care was provided in settlement nursing stations, at a base hospital manned by general practitioners, and at a teaching hospital in Winnipeg. Of the... | 709,174 | [
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Untrained community help in the rehabilitation of stroke sufferers with language disorder. | The Newcastle Speech-After-Stroke Project is one of many schemes in Britain that have used untrained helpers to set up community clubs and home visiting for dysphasic stroke sufferers. To examine the contribution to rehabilitation made by such activities, patients' language abilities and social confidence were assessed... | 709,213 | [
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Anti-acetylcholine-receptor antibody concentrations after thymectomy in patients with myasthenia gravis. | Serum concentrations of anti-acetylcholine-receptor (anti-AChR) antibody were measured in patients with myasthenia gravis. In those patients undergoing thymectomy concentrations were measured before and after the operation to see whether there might be a connection between the thymus and antibody production. We found n... | 709,215 | [
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Minimum information needed by prescribers. | The prescriber needs adequate and concise information about each product that he uses, to allow him to obtain optimal effects while minimising harm. Neither the present UK data sheets nor their equivalents in other countries have succeeded in providing such information clearly or completely. This paper develops the pro... | 709,266 | [
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The Safety Net and preregistration posts. | The Safety Net is a clearing system that collects and distributes information about preregistration posts remaining unallocated after as many doctors as possible have been placed by local efforts. Provided that the local systems operate in the final year, the Safety Net should ensure that each student has a post alloca... | 709,268 | [
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Unsuspected gonococcal infection in female patients. | Four hundred and ten female patients attending obstetric and gynaecological outpatient departments were investigated for possible gonococcal infection. All were in their reproductive phase. Forty-two (10.2%) of them harboured Neisseria gonorrhoeae. Of the infected patients, 40.5% had no symptoms at all. Investigation w... | 709,347 | [
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Changes in catecholamine turnover in the anterior part of the mediobasal hypothalamus and the medial preoptic area in response to hyperprolactinemia in ovariectomized rats. | High serum prolactin levels in ovariectomized rats were induced by transplantation of additional pituitaries under the kidney capsule. Such high prolactin levels reduced serum LH but not FSH levels 3 days after pituitary transplantion. LH and FSH values were at a control levels at day 15 and above these levels at day 2... | 709,355 | [
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Short-term stressor effects of reserpine. | The effects of reserpine on plasma glucose, FFA and cholesterol and on adrenal cholesterol were determined in 1-and 21-d-old chicks over a 24-h period. 2. Irrespective of age, reserpinised chicks became hyperglycaemic and hypocholesteraemic, their stores of adrenal cholesterol were depleted and the mobilisation of the ... | 709,393 | [
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Oestrogen binding proteins in bone cell cytosol. | Attempts were made to demonstrate the presence of specific oestrogen binding proteins ("receptors") in bone cells. High speed cytosol preparations of bone were incubated with several concentrations of radioactive oestradiol alone and with radioactive oestradiol in the presence of a specific antioestrogen, Nafoxidine. S... | 709,407 | [
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Metabolism of the isolated perfused rabbit heart. I. Responses to anoxia and reoxygenation. II. Energy stores. | Cardiac performance, substrate utilization, and creatine kinase (CK) release were studied in Langendorff rabbit hearts during aerobic perfusion, 25 min of anoxia, and 75 min of reoxygenation. In study I (n = 40), increasing glucose availability during aerobic perfusion enhanced substrate utilization without influencing... | 709,425 | [
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[Identification of actinomycetes with antifungal activity which do not affect Rhizobium meliloti]. | Thirteen isolates of actinomycetes that have broad antifungal activity and do not affect two efficient strains of Rhizobium meliloti were identified as: Nocardia autotrophica, Streptomyces antimycoticus, S. anulatus, S. capoamus, S. lydicus, S. murinus, S. roseo-luteus, and S. thermotolerans. | 709,436 | [
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[Thalassemia in French-speaking Quebec residents]. | Eighty-five cases of beta-thalassemia minor were found between January 1975 and November 1977 in 18 families of French-speaking Quebeckers without Mediterranean ancestry. Most of the families had settled in Quebec more than 200 years ago, largely in Portneuf county. This is the first report of such a number of cases of... | 709,470 | [
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Notes on the treatment of anhedonia. | This paper discusses the concept of anhedonia defined as the inability to experience pleasure. Many authors have noted the presence of anhedonia as a personality feature in patients with schizophrenia and other disorders. Anhedonia apparently begins early in life in relation to pathological reactions within the core fa... | 709,497 | [
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Carcinoembryonic antigen (CEA) in the cancer family syndrome. | We present findings on plasma CEA in relatives and spouses from six kindreds manifesting the Cancer Family syndrome. The CEA distributions per se were transformed to square root CEA to correct for skewness and kurtosis. Significant effects of age and duration of smoking were adjusted for by linear regression. Relatives... | 709,527 | [
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Systematic restaging in patients with Hodgkin's disease: a Southwest Oncology Group Study. | Eighty-two patients with advanced Hodgkin's disease who were in apparent complete remission (CR) after receiving 10 courses of combination chemotherapy were systematically reevaluated for persisting disease. Occult Hodgkin's disease was found in 10 (12%) of these patients and was predominantly present in nodal sites (9... | 709,542 | [
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Hepatic arterial BCNU: a pilot clinical-pharmacologic study in patients with liver tumors. | BCNU at a dose of 200 mg/m2 was administered in a 60-minute hepatic arterial (HA) infusion to three patients with liver-predominant neoplastic disease. Nitrosourea blood levels were measured during the 60-minute infusion and for 30 minutes after completion of the infusion in samples obtained simultaneously from a hepat... | 709,552 | [
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Chemotherapy for colorectal cancer with a combination of 5-fluorouracil, mitomycin C, adriamycin, and cytosine arabinoside: a pilot study. | Fifty-four patients with clinical evidence of residual colorectal adenocarcinoma following surgical removal of the primary tumor were treated with a combination of 5-fluorouracil, mitomycin C, adriamycin, and cytosine arabinoside. The objective response rate in these patients was 17%. Bone marrow suppression was the ma... | 709,556 | [
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A three-dimensional study of organelle interrelationships in regenerating rat liver. 1. The Gerl-system. | Arguments are put together indicating that the GERL-system, or at least its thick membrane and part of its content are derived from the mature Golgi cisterna. Just like every Golgi cisterna does, the GERL shows direct continuities with ER, from which a complement of products may be supplied. Rigid lamellae are interpre... | 709,608 | [
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Arabinosyl nucleosides. XII. Influence of arabino-furanosylthymine on growth of L5178y cells. | The antibiotic 1-beta-D-arabinofuranosylthymine (araThd) is a potent inhibitor of the growth of mouse lymphoma cells (L5178y). The ED50 concentration was found to be 9.8 muM. The cells die as a consequence of an unbalanced growth. The cytostatic activity of araThd can be abolished by coincubation with dThd and dUrd but... | 709,683 | [
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Arabinosyl nucleosides. XIII. Influence of arabinofuranosylthymine on DNA-, RNA- and protein-synthesizing systems in vitro. | The natural metabolite of the sponge Cryptotethya crypta, arabinofuranosylthymine (araThd), is intracellularly phosphorylated to araTTP. The present study demonstrates that araTTP inhibits both isolated DNA polymerases alpha and the DNA polymerase beta from L5178y cells competitively with respect to the analogous subst... | 709,684 | [
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[Rectal agenesis with absent bladder in a female newborn (author's transl)]. | This paper reports a very unusual variety of female ano-rectal agenesis without fistula associated with severe urogenital malformations. The patient died of renal failure and, at autopsy, both ureters draining dysplastic ectopic kidneys and two vaginas, either with its corresponding uterus and annexa were found opening... | 709,704 | [
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[Osteoarticular tuberculosis in children (author's transl)]. | A group of sixteen children suffering from osteoarticular tuberculosis were seen over the past five years in the Belgrade Paediatric Surgery Clinic. This disease is now extremely rare and effects chiefly children born outside maternity departments and not receiving BCG vaccination at birth for different reasons. The os... | 709,713 | [
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The effects of heparin pretreatment on plasma histamine following thermal injury in rats and cats. | An elevated plasma histamine level in response to thermal injury is demonstrated in the rat and cat. In cats, the initial elevation of plasma histamine occurred within the first 15 minutes following thermal injury, and this was followed by a second rise between 60 and 120 minutes. Heparin pretreatment markedly reduced ... | 709,736 | [
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Isometric relaxation of rat myocardium at end-systolic fiber length. | In a "physiologically sequenced" contraction (PSC), which loads the isolated muscle preparation in a manner which approximates that of the intact heart, isometric relaxation precedes isotonic relaxation and occurs at minimum ("end-systolic") length. We studied the effects of inital muscle length, load, temperature, cal... | 709,748 | [
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0.07775214,
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0.070754,
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-0.4621867,
0.1490153,
-0.3147194,
0.4055671,
0.535807,
0.0310758,
-0.09120838,
... |
Modulation by prostaglandin synthesis inhibitors of the action of exogenous angiotensin II on glomerular ultrafiltration in the rat. | We studied the effects of angiotensin II (A II) infusion, with and without inhibition of prostaglandin (PG) synthesis, on the determinants of glomerular ultrafiltration in 27 plasma volume-expanded Munich-Wistar rats. The effects of PG inhibition alone and infusion of vehicle alone also were investigated. With a presso... | 709,751 | [
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... |
Early imaging of experimental myocardial infarction by intracoronary administraion of 131I-labelled anticardiac myosin (Fab')2 fragments. | We examined the feasibility of early imaging of myocardial infarcts by intracoronary injection of 131I-labelled cardiac myosin-specific antibody (Fab')2. The left anterior descending coronary artery was occluded for 5 hours by a balloon catheter introduced through the carotid artery in 12 dogs. The catheter was withdra... | 709,769 | [
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0.147597,
0.3351008,
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0.1094983,
... |
Myocardial infarction size from serial CPK: variability of CPK serum entry ratio with size and model of infarction. | To study the variability of the fraction of CPK released from the infarcted heart which enters the serum (serum entry ratio, or SER) with size and model of infarction, nine dogs underwent homogeneous infarctions (LAD ligation) of varying sizes, and 10 dogs underwent scattered infarctions (left coronary embolization). I... | 709,770 | [
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... |
Cardiac sarcoid: a clinicopathologic study of 84 unselected patients with systemic sarcoidosis. | Although sarcoid may involve the myocardium, there is little information on its incidence or significance. We studied 84 consecutive autopsied patients with sarcoidosis. The patients ranged in age from 18--80 years (average 46 years) and 61% were women; 23 (27%) of them had myocardial granulomas. In eight (35%) these w... | 709,777 | [
-0.3326375,
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0.2314629,
0.6341931,
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... |
Complement changes during exercise-induced asthma. | Two groups of asthmatic children, one with and one without a history of post-exercise wheezing, and one non-asthmatic adult, were exercised on a treadmill, and their complement levels were measured before and after exercise. The first group of patients had the most obvious fall in FEV 1 and all showed a slight rise in ... | 709,794 | [
-0.1268141,
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0.1640182,
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Semi-automatic data processing in clinical chemistry. | A semi-automatic system for data processing in the Clinical Chemistry Department of the School of Pathology, Johannesburg, is outlined. Careful planning of workflow in the laboratory can provide a better interface of laboratory results with a manual cumulative reporting system in which technologists and clerks co-ordin... | 709,806 | [
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A study of factors affecting laboratory workload. | 1. The use of a mathematical modelling technique is described. The factors influencing the day to day variation in laboratory workload were investigated to provide for accurate management forecasts. Analysis by linear stepwise regression showed that a potentially controllable factor the clinician ordering habits, accou... | 709,812 | [
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Radioenzymatic assay of DOPA (3,4-dihydroxyphenylalanine). | We modified the single-isotope radioenzymatic assay for catecholamines [Life Sci. 21, 625 (1977)] to assay 3, 4-dihydroxyphenylalanine (DOPA). DOPA decarboxylase is used to convert DOPA to dopamine, which concurrently is converted to [3H]-3-O-methyldopamine in the presence of catechol-O-methyltransferase and [methyl-3H... | 709,823 | [
-0.4519725,
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0.4619831,
0.1753053,
0.4717197,
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Effect of in vitro hemolysis on chemical values for serum. | Hemolysis in serum specimens is commonplace. This study examines the effect of hemolysis on results of selected chemical assays. Hemolysis was simulated by adding hemolysate to serum to give hemoglobin concentrations of 90 to 2800 mg/liter and a rating by technologists of 0 to 4 + hemolyzed. The effect of hemolysis on ... | 709,831 | [
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Determination of 3-methoxy-4-hydroxyphenylpyruvic acid, 3,4-dihydroxyphenylethylene glycol, and 3,4-dihydroxyphenylmandelic acid in urine by mass fragmentography, with use of deuterium-labeled internal standards. | We report the determination of 3-methoxy-4-hydroxyphenylpyruvic acid, 3,4-dihydroxyphenylmandelic acid, and 3,4-dihydroxyphenylethylene glycol in urine, by use of gas chromatography/mass spectrometry in combination with a simple purification method and deuterium-labeled internal standards. Normal excretion values in te... | 709,835 | [
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0.132113,
0.3100391,
0.2966093,
0.1072508,
-0.277653... |
Manual and centrifugal analyzer determination of cholesterol and triglycerides with single-vial enzymatic reagents. | We have assessed Calbiochem single-vial enzymatic reagent systems for the analysis for cholesterol and triglycerides, using manual and centrifugal analyzer techniques. Analysis for cholesterol by both techniques had acceptable performance by the short-term criteria of the Center for Disease Control (CDC) during this st... | 709,840 | [
0.06632618,
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0.3069778,
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Mechanized micro-scale determination of protein in platelet pellet sonicates. | With the method described here, samples can be assayed at the rate of 40/h, with increased reproducibility. As described, the method covers an analytical range of 1 to 7 g/liter, but it can be readily adapted to measure different ranges of concentration in other protein preparations. | 709,841 | [
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0.2870009,
0.3941719,
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0.0298671... |
Enzymatic determination of plasma ammonia: evaluation of Sigma and BMC Kits. | We compared two kit methods for the enzymatic determination of plasma ammonia. The procedures involved measuring the decrease in absorbance at 340 nm resulting from the consumption of NADH in the Sigma kit, NADPH in the BMC kit. Both kits gave acceptable results for aqueous samples, but for plasma specimens values with... | 709,845 | [
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0.3481171,
0.1360735,
0.1863412,
0.22991... |
3,4-Dimethoxyphenylethylamine excretion of normals and schizophrenics, behaviour during total fasting. | A specific and sensitive radioimmunoassay for the determination of 3,4-dimethoxyphenylethylamine (3,4-DMPEA) in urine was developed. In 5 fasting healthy volunteers excretion of 3,4-DMPEA was not diminished, indicating that this substance can be regarded as an endogenous metabolite. In addition, the time profile of the... | 709,888 | [
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0.1710512,
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0.3620432,
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Pituitary-gonadal function in XYY and XXY men identified in a population survey. | Evidence on pituitary-gonadal function in XYY subjects has been inconclusive and based, for the most part, on selected samples such as institutionalized individuals or subjects examined for particular behavioural or medical characteristics. We report the results of a double-blind hormonal study of a sample from an enti... | 709,893 | [
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0.347367,
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-... |
The effect of alpha adrenergic receptor blockade on the glucagon-induced growth hormone response. | The effect of a alpha adrenergic blockade (phentolamine) on glucagon induced growth hormone response was tested in five normal men. There was no significant difference in growth hormone concentrations between the glucagon test and the glucagon-phentolamine test (mean maximum level, 23.4 +/- 3.7 ng/ml and 23.1 +/- 5.9 n... | 709,896 | [
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0.06669466,
0.3856645,
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0.02881778,
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Spontaneous and lectin-dependent cellular cytotoxicity by lymphocyte subpopulations against cell lines susceptible or resistant to spontaneous cytotoxicity. | In the present study we have investigated whether cell lines, which are resistant to spontaneous cytotoxicity, can be killed by lectin-dependent cellular cytotoxicity (LDCC), the expression of EAC (7S) receptors on LDCC effector cells, and the relationship between spontaneous cytotoxicity and LDCC when EAC (7S) recepto... | 709,908 | [
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0... |
Correlation between hypersensitivity to parenteral chymopapain and the presence of IgE anti-chymopapain antibody. | A solid phase radioimmunoassay, similar to the RAST, was developed in an attempt to predict anaphylactic reactions in patients injected with the proteolytic enzyme chymopapain, used in therapy for prolapsed intervertebral disc. The test measured the serum content of anti-chymopapain antibodies of the IgE class. Of 1263... | 709,910 | [
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-... |
The acquisition and loss of antigen-specific cellular immune responsiveness in acute and chronic schistosomiasis in man. | To characterize the development and evolution of cellular immune responsiveness in individuals infected with the parasite Schistosoma mansoni, we studied fifteen patients with acute, subacute and chronic schistosomiasis. Lymphocytes from the three acutely infected patients responded vigorously to schistosome antigens i... | 709,912 | [
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... |
An experimental model of osteogenesis: a closed in vivo culture system using diffusion chambers. | Part of young mouse radii were isolated and transplanted into an intraperitoneal Millipore diffusion chamber. The survival of the implants was followed for 22 days, using morphological criteria, and by autoradiography with tritiated thymidine. Periosteal cells and epiphyseal plate chondrocytes survived well for one to ... | 709,943 | [
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0.009534988,
0.0486523... |
Detection of active bleeding from ruptured aortic aneurysm by emergency radionuclide angiography. | Radionuclide angiography of the abdominal aorta provides hemodynamic information of the kidneys, aorta and aneurysm as well as the location and extent of aneurysm. Visualization of early abnormal activity in the pelvic region simultaneously with iliac artery visualization is thought to be a specific finding of active b... | 709,980 | [
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0.5850094,
0.2484037,
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Radionuclide demonstration of relative increased blood flow in uniappendicular secondary hypertrophic osteoarthropathy. | A rare case of hypertrophic osteoarthropathy (HO) limited to one lower extremity is described in a male with a history of familial polyposis coli and bilateral aortofemoral grafts. The precise etiology remains unknown. Radiography depicted the HO, but 99m Tc-methylene diphosphonate imaging showed more extensive involve... | 709,981 | [
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0.05694229,
0.3017835,
0.2350346,
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Computed tomography in the diagnosis of diseases of the paranasal sinuses. | The authors investigated 31 patients suffering from benign and malignant lesions of the paranasal sinuses. Clinical, conventional radiological methods and computed tomography were used. In benign lesions CT added little significant information to that obtained by conventional radiological methods. In malignant lesions,... | 710,035 | [
-0.3449021,
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0.2255158,
0.1667964,
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Primary adenocarcinoma of the upper oesophagus. | Adenocarcinoma of the upper one-third of the oesophagus is an uncommon entity. A review of the literature reveals 20 reported cases. This paper reports an additional case. The lesion may arise from oesophageal glands, foci of ectopic gastric mucosa, or a Barrett's oesophagus. In contrast with squamous cell carcinomas s... | 710,037 | [
-0.2427013,
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0.2809066,
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Radiology of the gastrointestinal abnormalities seen in patients with adult hepatorenal polycystic disease. | A review of 97 patients with adult hepatorenal polycystic disease (AHRPD) revealed a significant number of patients with gastrointestinal symptoms as the initial or primary manifestation of their disease. The typical appearance of the gastrointestinal barium examinations is presented. | 710,041 | [
-0.1761015,
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Effects of chronic renal insufficiency and metabolic acidosis on glutamine metabolism in man. | 1. Arterial concentration and arterial-venous differences of glutamine across the kidney, forearm, hepato-splanchnic bed and brain were measured in patients with chronic renal insufficiency and in patients with normally functioning kidneys before and during chronic ammonium chloride acidosis. 2. In chronic renal insuff... | 710,053 | [
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... |
Multimodal outpatient group treatment for the psychiatrically disabled. | Outpatient clinics gradually accumulate patients with longstanding disabilities. The traditional treatment approach is to see such patients in brief, intermittent, individual visits. Staff generally dislikes treating such patients and patients may, in part, maintain their symptoms in order to maintain ties with a nurtu... | 710,067 | [
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0.1878331,
0.038239... |
Transcultural aspects of psychiatric patients in Qatar. | The illness behaviour of Qatari psychiatric patients is defined by the nature of their symptomatology. The importance of somatic symptoms in determining the patient role and patient-doctor relationship is discussed in the light of cultural characteristics of the Qatari community. Delusory cultural beliefs related to po... | 710,076 | [
-0.1356321,
-0.1715824,
0.2120261,
-0.09228621,
0.2399479,
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-0.3656934,
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0.1163094,
0.008605514,
0.1308724,
-0.2847591,
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0.07244497,
-0.7734321,
0.1251563,
-0.5037888,
-0.08086158,
-0.05594932,
0.1713265,
-0.127669... |
Endorphin release: a possible mechanism of acupuncture analgesia. | The action of acupuncture stimulation on analgesia has been investigated. The brain and serum extracts of acupunctured rabbits injected into rabbits produced a marked analgesic effect on the recipient, as shown by a great increase of their pain threshold. This effect is counteracted by a specific opiate anatagonist, na... | 710,079 | [
0.06058255,
0.1311077,
0.06570067,
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0.03771428,
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0.08844385,
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0.100043,
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0.05179222,
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0.08531331,
-0.5673668,
0.10238,
0.02914607,
-0.01471689,
-0.06185635,
0.2634611,
-0.2871201... |
Computed tomography in the evaluation of sella and parasella lesions: the value of sagittal and coronal reconstructions. | A method is described whereby contiguous, thin-section (3 mm) axial CT scans are obtained followed by computer manipulation of the data to reconstruct good quality images in sagittal and coronal planes. The application of this technique in the evaluation of sella and parasella abnormalities is discussed. In our experie... | 710,093 | [
-0.1336545,
0.07872356,
0.08540177,
-0.2836491,
-0.1052951,
-0.3366635,
-0.2191612,
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0.06093482,
0.1679685,
0.0760335,
-0.3170463,
-0.2998119,
-0.1063794,
-0.3921715,
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-0.448819,
0.06160701,
-0.08572577,
-0.000002030719,
0.1541739,
0.1050571,
-0.052... |
"Semantic" and "acoustic" errors of aphasic and schizophrenic patients in a sound-picture matching task. | Broca's aphasics, Wernicke's aphasics, brain-damaged patients without aphasia, and chronic schizophrenics were tested on a task to match meaningful sounds to one of four pictures. One of the depicted objects was the natural source of the sound, one was an object belonging to the same semantic category as the correct ob... | 710,149 | [
-0.1386125,
0.3850263,
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0.08083305,
0.5559208,
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0.2922406,
0.1314496,
0.08843488,
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-0.2522311,
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0.03922143,
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-0.3261773,
-0.01574197,
-0.1191503,
-0.03771728,
0.1781201,
0.1468216,
-0.09669677,... |
Analytic and global strategies in copying designs by unilaterally brain-damaged patients. | Different strategies in copying designs were investigated in unilaterally brain-damaged patients. Site of lesions (right or left) and presence or absence of aphasia, seen as a planning disorder, were taken in consideration. Aphasic patients proved to be more inclined to use an analytic strategy rather than a global one... | 710,150 | [
-0.2523145,
0.4907704,
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0.3118726,
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0.1322233,
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0.1784545,
0.05425702,
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0.1021343,
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-0.2581187,
0.1542271,
-0.6037263,
-0.1136841,
0.06293928,
0.2041126,
-0.05074884,
... |
Indigenous and expatriate addicts in Laos: a comparison. | Opium addiction has been reported among virtually all large ethnic groups in Asia. Conspicuous by its absence has been any mention of addiction among the Lao, a people surrounded by poppy-growing tribal groups. A sample of Lao patient-addicts are here compared to expatriate Asian addicts in Laos. Lao and expatriate add... | 710,168 | [
0.04297622,
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0.4381904,
-0.2229221,
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0.1143981,
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0.1515702,
0.004236706,
0.08751052,
0.2316243,
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0.3045387,
0.01018131,
-0.3001406,
-0.2051479,
0.135478,
-0.1645376,
... |
Scars of experience: the art of moxibustion in Japanese medicine and society. | Beliefs and practices surrounding moxibustion, a cautery technique used in Japan, are analyzed to demonstrate that the concept of holism is culture-bound and that the practice of East Asian medicine is often reductionistic. Pluralistic traditional medical belief systems of historical and contemporary Japan are discusse... | 710,169 | [
-0.08824555,
0.2620917,
0.06029624,
0.005606474,
0.1769141,
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0.1334196,
0.3886438,
0.05616717,
0.0632136,
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0.2023777,
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-0.0006378597,
-0.2356399,
-0.1528253,
0.05220704,
0.1709396,
-0.51078... |
Ethno-behaviorism and the culture-bound syndromes: the case of Amok. | The phenomenon of amok is reviewed in order to demonstrate the heuristic value of an ethno-behavioral model of culture-bound syndromes. The notion that culture-bound syndromes share underlying common disease forms is rejected. Instead, the ethno-behavioral model postulates that culture-bound syndromes consist of cultur... | 710,174 | [
-0.3487244,
-0.1831644,
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0.2854451,
0.00518636,
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0.2342278,
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0.04037693,
0.08559365,
0.1071106,
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0.1035309,
0.1258245,
-0.6347217,
0.4202436,
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0.1472717,
0.2292201,
0.09710821,
-0.05087809,
... |
Defining the comminity context for parent-child relations: the correlates of child maltreatment. | This report presents the results of studies designed to illustrate the use of child maltreatment report data as social indicators of the quality of life for families. It addresses the feedback function of family-support systems and links maltreatment to the overall balance of stresses and supports in the neighborhood c... | 710,189 | [
-0.3000228,
0.2084716,
0.1312404,
0.08550213,
0.03417889,
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0.1157047,
0.08411276,
0.08877845,
0.05155623,
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0.2726852,
0.5972057,
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0.1485843,
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0.09018916,
0.05605777,
0.2776078,
0.1037843,
... |
[The hypertensive heart. VII. Effect of atenolol on the function, coronary haemodynamics and oxygen uptake of the left ventricle (author's transl)]. | After acute beta-adrenergic blockade (5 mg atenolol intravenously) in 11 patients with essential hypertension but no heart failure arterial blood pressure and inotropic state fell slightly (-5.4% and -7.5%, respectively), but there was a definite decrease in heart rate (-13.8%), cardiac index (-11.5%) and cardiac work ... | 710,288 | [
0.1470108,
0.1728786,
-0.354881,
-0.08660173,
0.2363261,
-0.2925984,
-0.01509599,
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-0.327785,
0.08057996,
-0.1602879,
0.2027995,
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0.2161893,
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-0.5550137,
0.3177264,
0.1105183,
0.2641765,
0.1668784,
0.06659649,
-0.08950604,
0... |
[The diagnostic value of determining serum-mercaptans in liver disease (author's transl)]. | Aliphatic mercaptans (aethanthiol, methanthiol, dimethylsulphide) can be measured in serum with a simple and rapid gaschromatographic method. The test takes 30 minutes. Aethantiol was found to be increased ten-fold (P less than 0.0001) in patients with acute hepatic failure (endogenous coma), while in exogenous hepatic... | 710,290 | [
-0.3373619,
0.02245926,
-0.1759202,
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0.2245546,
0.08461797,
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0.004708536,
0.1266538,
-0.05485781,
-0.02181689,
0.1074381,
0.2375582,
0.2769606,
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0.06262062,
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0.4844104,
0.05578538,
0.3266425,
0.1940685,
-0.2766634,
-0.09647757,
... |
Plasma TSH and prolactin response to insulin induced hypoglycemia in patients with hypothalamic pituitary disorders. | Plasma TSH and prolactin (PRL) responses to insulin-induced hypoglycemia (ITT) were examined in 37 patients with various hypothalamic pituitary disorders. Four patients showed a definite TSH response to ITT. They were 2 patients with suspected pinealoma with diabetes insipidus (DI), a patient with pituitary adenoma and... | 710,372 | [
-0.04336365,
-0.4442479,
-0.1799068,
-0.3760577,
0.2756728,
-0.4438879,
-0.2983923,
0.002442745,
0.2058649,
0.4146999,
0.1239112,
0.2715087,
-0.3425385,
-0.1256179,
-0.2028552,
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-0.2839775,
0.09097081,
-0.04231483,
-0.129404,
0.1372219,
-0.0601125,
0.3342712,
... |
Methods of electrophoretical application of estrogen to a single neuron of the brain under in vivo and in vitro conditions. | The techniques of the electrophoretical study of hormone sensitivities of neurons were examined in vivo and in vitro. For the in vivo study, estrogen and other hormones were applied electrophoretically to neurons of the rat brain of both sexes under urethane anesthesia. Some neurons were sensitive to estrogen and their... | 710,374 | [
0.07128257,
-0.1208704,
0.0764403,
0.02930837,
-0.124555,
-0.230377,
-0.4061495,
-0.3053612,
0.1828191,
0.1581679,
0.1283502,
0.2311164,
0.3276271,
0.1140547,
-0.3657554,
0.1801491,
-0.3848079,
0.165166,
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0.07763661,
0.1359313,
-0.08184507,
0.1743443,
-0.184... |
Hormonal changes in serum in young men during prolonged physical strain. | The endocrine response to severe physical strain including lack of sleep has been investigated in army personnel during a combat course of 5 days' duration. The thyroxine (T4) concentration in serum increased during the first 24 h, and then declined at a rate corresponding to a halflife of 7.6 days and on day 6 had rea... | 710,393 | [
-0.09874862,
-0.1131037,
-0.1863153,
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-0.1675557,
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0.1045196,
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0.196859,
0.1629632,
0.0749305,
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0.2909381,
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-0.1440326,
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0.0584296,
0.0755854,
0.08993436,
0.1447274,
0.1391581,
-0.1329724,
... |
Subcellular localization of two long-chain acyl-coenzyme-A synthetases in Candida lipolytica. | Studies have been made on the subcellular localization of two long-chain acyl-coenzyme-A synthetases as well as glycerolphosphate acyltransferase and the acyl-CoA-oxidizing system in Candida lipolytica grown on oleic acid. Acyl-CoA synthetase I is distributed among different subcellular fractions, including microsomes ... | 710,394 | [
0.01028437,
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-0.01024211,
0.07975141,
0.05104687,
0.04491962,
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0.3307371,
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0.1399845,
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0.3471,
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0.2695759,
0.4979922,
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0.4291042,
0.49622,
-0.09421329,
0.1... |
Adaptive responses of enzymes of carbohydrate and lipid metabolism to dietary alteration in genetically obese Zucker rats (fa/fa). | 1. Measurements have been made of the activities of enzymes of the glycolytic route, the pentose phosphate pathway, the tricarboxylic acid cycle and lipogenesis in liver and adipose tissue from genetically obese (fa/fa) rats and their lean litter mates (fa/ --). The effect of food restriction for a period of three week... | 710,395 | [
0.08727877,
0.005442041,
0.02103938,
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0.2801932,
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0.1998633,
0.2410855,
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0.2861716,
0.147767,
0.1961198,
0.07307787,
0.279231,
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0.0470079,
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0.1235483,
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0.1437057,
0.1173921,
0.2167312,
-0.4292252,
-0.00... |
The complete amino-acid sequence of histone H2B(3) from sperm of the sea urchin Parechinus angulosus. | The primary structure of a third H2B histone isolated from sperm of the sea urchin Parechinus angulosus has been determined. H2B(3) consists of a polypeptide chain of the following 148 amino acid residues: Pro-Arg-Ser-Pro-Ala-Lys-Thr-Ser-Pro-Arg-Lys-Gly-Ser-Pro-Arg-Lys-Gly-Ser-Pro-Arg-Lys-Gly-Ser-Pro-Ser-Arg-Lys-Ala-Se... | 710,402 | [
0.2245627,
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0.2876401,
0.1108427,
0.02750528,
0.06240985,
0.160778,
0.3615598,
0.08393354,
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0.3034263,
0.0323744,
0.101957,
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0.6347244,
0.21262,
-0.006991646,
0.3599381,
0.3458114,
-0.1103557,
-0.186... |
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