| --- |
| license: other |
| tags: |
| - gwas |
| - polygenic-risk-score |
| - psychiatric-genetics |
| - pgc |
| --- |
| |
| # Bipolar Disorder GWAS Summary Statistics (PGC) |
|
|
| Mirror of Psychiatric Genomics Consortium (PGC) summary statistics for |
| **Bipolar Disorder** (bip2019), redistributed in a single Apache Parquet file |
| for use with [OpenMed Genomics](https://huggingface.co/spaces/turmex2/openneuro-genomics). |
|
|
| ## Source |
|
|
| - **Primary citation:** Stahl et al., Nature Genetics 2019; Mullins et al., Nature Genetics 2021 |
| - **Original distributor:** Psychiatric Genomics Consortium |
| (<https://pgc.unc.edu/for-researchers/download-results/>) |
|
|
| This mirror exists only because the upstream OpenMed mirror became |
| inaccessible. No modifications have been made to the underlying data; |
| per-shard parquet files were concatenated into a single file for |
| convenient streaming. |
|
|
| ## File |
|
|
| `pgc-bipolar_bip2019.parquet` -- one Apache Parquet file containing the full summary |
| statistics table in the PGC's published schema (SNP, CHR, BP, A1, A2, |
| FRQ, OR/BETA, SE, P, ...). |
|
|
| ## Usage |
|
|
| ```python |
| import polars as pl |
| df = pl.read_parquet( |
| "https://huggingface.co/datasets/turmex2/pgc-bipolar/resolve/main/pgc-bipolar_bip2019.parquet" |
| ) |
| ``` |
|
|
| ## License & terms of use |
|
|
| PGC summary statistics are released for non-commercial research use only. |
| Do not attempt to re-identify individuals. Results derived from these |
| data are **not** a clinical diagnosis. See the original publication for |
| the full data-use agreement. |
|
|
