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PMC212319_Fig3_4.jpg | What object or scene is depicted here? | A. Real time image of the translocation of ARF1-GFP to the plasma membrane. HeLa cells that had been stably transfected with ARF1-GFP were transiently transfected with myc-ARNO, serum starved overnight, and treated with 100 nM insulin. Images were collected every 30 seconds using a Molecular Dynamics 2001 confocal micr... |
PMC212319_Fig3_9.jpg | What object or scene is depicted here? | A. Real time image of the translocation of ARF1-GFP to the plasma membrane. HeLa cells that had been stably transfected with ARF1-GFP were transiently transfected with myc-ARNO, serum starved overnight, and treated with 100 nM insulin. Images were collected every 30 seconds using a Molecular Dynamics 2001 confocal micr... |
PMC212319_Fig3_2.jpg | Can you identify the primary element in this image? | A. Real time image of the translocation of ARF1-GFP to the plasma membrane. HeLa cells that had been stably transfected with ARF1-GFP were transiently transfected with myc-ARNO, serum starved overnight, and treated with 100 nM insulin. Images were collected every 30 seconds using a Molecular Dynamics 2001 confocal micr... |
PMC212319_Fig3_1.jpg | What stands out most in this visual? | A. Real time image of the translocation of ARF1-GFP to the plasma membrane. HeLa cells that had been stably transfected with ARF1-GFP were transiently transfected with myc-ARNO, serum starved overnight, and treated with 100 nM insulin. Images were collected every 30 seconds using a Molecular Dynamics 2001 confocal micr... |
PMC212319_Fig3_5.jpg | What does this image primarily show? | A. Real time image of the translocation of ARF1-GFP to the plasma membrane. HeLa cells that had been stably transfected with ARF1-GFP were transiently transfected with myc-ARNO, serum starved overnight, and treated with 100 nM insulin. Images were collected every 30 seconds using a Molecular Dynamics 2001 confocal micr... |
PMC212319_Fig3_7.jpg | What's the most prominent thing you notice in this picture? | A. Real time image of the translocation of ARF1-GFP to the plasma membrane. HeLa cells that had been stably transfected with ARF1-GFP were transiently transfected with myc-ARNO, serum starved overnight, and treated with 100 nM insulin. Images were collected every 30 seconds using a Molecular Dynamics 2001 confocal micr... |
PMC212319_Fig3_3.jpg | What is the main focus of this visual representation? | A. Real time image of the translocation of ARF1-GFP to the plasma membrane. HeLa cells that had been stably transfected with ARF1-GFP were transiently transfected with myc-ARNO, serum starved overnight, and treated with 100 nM insulin. Images were collected every 30 seconds using a Molecular Dynamics 2001 confocal micr... |
PMC212319_Fig3_0.jpg | What is the central feature of this picture? | A. Real time image of the translocation of ARF1-GFP to the plasma membrane. HeLa cells that had been stably transfected with ARF1-GFP were transiently transfected with myc-ARNO, serum starved overnight, and treated with 100 nM insulin. Images were collected every 30 seconds using a Molecular Dynamics 2001 confocal micr... |
PMC212319_Fig3_8.jpg | What key item or scene is captured in this photo? | A. Real time image of the translocation of ARF1-GFP to the plasma membrane. HeLa cells that had been stably transfected with ARF1-GFP were transiently transfected with myc-ARNO, serum starved overnight, and treated with 100 nM insulin. Images were collected every 30 seconds using a Molecular Dynamics 2001 confocal micr... |
PMC212693_pbio-0000014-g001_10.jpg | What is the core subject represented in this visual? | FRAP of HP1–GFP Reveals a Dynamic Association with HeterochromatinA fraction of a heterochromatic cluster (arrowhead) was bleached by a laser pulse, and recovery of fluorescence was monitored by time-lapse imaging. Images were kindly provided by Thierry Cheutin and Tom Misteli. |
PMC212693_pbio-0000014-g001_15.jpg | What is the central feature of this picture? | FRAP of HP1–GFP Reveals a Dynamic Association with HeterochromatinA fraction of a heterochromatic cluster (arrowhead) was bleached by a laser pulse, and recovery of fluorescence was monitored by time-lapse imaging. Images were kindly provided by Thierry Cheutin and Tom Misteli. |
PMC212693_pbio-0000014-g001_13.jpg | What object or scene is depicted here? | FRAP of HP1–GFP Reveals a Dynamic Association with HeterochromatinA fraction of a heterochromatic cluster (arrowhead) was bleached by a laser pulse, and recovery of fluorescence was monitored by time-lapse imaging. Images were kindly provided by Thierry Cheutin and Tom Misteli. |
PMC212699_pbio-0000021-g001_22.jpg | What key item or scene is captured in this photo? | Expression of Three Transcription Factors during Early Bacteriocyte Development(A) Drawings of some stages of pea aphid embryonic development, approximately to scale. Embryos develop viviparously within a follicular epithelium of the ovariole (data not shown). For a complete description, see Miura et al. (2003). Bacter... |
PMC212699_pbio-0000021-g001_21.jpg | What does this image primarily show? | Expression of Three Transcription Factors during Early Bacteriocyte Development(A) Drawings of some stages of pea aphid embryonic development, approximately to scale. Embryos develop viviparously within a follicular epithelium of the ovariole (data not shown). For a complete description, see Miura et al. (2003). Bacter... |
PMC212699_pbio-0000021-g001_18.jpg | What key item or scene is captured in this photo? | Expression of Three Transcription Factors during Early Bacteriocyte Development(A) Drawings of some stages of pea aphid embryonic development, approximately to scale. Embryos develop viviparously within a follicular epithelium of the ovariole (data not shown). For a complete description, see Miura et al. (2003). Bacter... |
PMC212699_pbio-0000021-g001_19.jpg | What object or scene is depicted here? | Expression of Three Transcription Factors during Early Bacteriocyte Development(A) Drawings of some stages of pea aphid embryonic development, approximately to scale. Embryos develop viviparously within a follicular epithelium of the ovariole (data not shown). For a complete description, see Miura et al. (2003). Bacter... |
PMC212699_pbio-0000021-g001_17.jpg | What key item or scene is captured in this photo? | Expression of Three Transcription Factors during Early Bacteriocyte Development(A) Drawings of some stages of pea aphid embryonic development, approximately to scale. Embryos develop viviparously within a follicular epithelium of the ovariole (data not shown). For a complete description, see Miura et al. (2003). Bacter... |
PMC212699_pbio-0000021-g001_20.jpg | What is being portrayed in this visual content? | Expression of Three Transcription Factors during Early Bacteriocyte Development(A) Drawings of some stages of pea aphid embryonic development, approximately to scale. Embryos develop viviparously within a follicular epithelium of the ovariole (data not shown). For a complete description, see Miura et al. (2003). Bacter... |
PMC300883_pbio-0020015-g001_35.jpg | Describe the main subject of this image. | Caspase Activity Is Required for Spermatid Individualization(A–C) Testis of different genotypes were visualized with antibodies specific for activated Drice (green). (A) Wild-type testis. Active DRICE is present in multiple elongated cysts. Cystic bulges (cb) and waste bags (wb) are indicated by arrows. (B and C) Teste... |
PMC300883_pbio-0020015-g001_40.jpg | What is being portrayed in this visual content? | Caspase Activity Is Required for Spermatid Individualization(A–C) Testis of different genotypes were visualized with antibodies specific for activated Drice (green). (A) Wild-type testis. Active DRICE is present in multiple elongated cysts. Cystic bulges (cb) and waste bags (wb) are indicated by arrows. (B and C) Teste... |
PMC300883_pbio-0020015-g001_36.jpg | Can you identify the primary element in this image? | Caspase Activity Is Required for Spermatid Individualization(A–C) Testis of different genotypes were visualized with antibodies specific for activated Drice (green). (A) Wild-type testis. Active DRICE is present in multiple elongated cysts. Cystic bulges (cb) and waste bags (wb) are indicated by arrows. (B and C) Teste... |
PMC300883_pbio-0020015-g001_39.jpg | What object or scene is depicted here? | Caspase Activity Is Required for Spermatid Individualization(A–C) Testis of different genotypes were visualized with antibodies specific for activated Drice (green). (A) Wild-type testis. Active DRICE is present in multiple elongated cysts. Cystic bulges (cb) and waste bags (wb) are indicated by arrows. (B and C) Teste... |
PMC300883_pbio-0020015-g001_38.jpg | What is the principal component of this image? | Caspase Activity Is Required for Spermatid Individualization(A–C) Testis of different genotypes were visualized with antibodies specific for activated Drice (green). (A) Wild-type testis. Active DRICE is present in multiple elongated cysts. Cystic bulges (cb) and waste bags (wb) are indicated by arrows. (B and C) Teste... |
PMC300883_pbio-0020015-g001_42.jpg | Can you identify the primary element in this image? | Caspase Activity Is Required for Spermatid Individualization(A–C) Testis of different genotypes were visualized with antibodies specific for activated Drice (green). (A) Wild-type testis. Active DRICE is present in multiple elongated cysts. Cystic bulges (cb) and waste bags (wb) are indicated by arrows. (B and C) Teste... |
PMC300883_pbio-0020015-g001_34.jpg | What is the focal point of this photograph? | Caspase Activity Is Required for Spermatid Individualization(A–C) Testis of different genotypes were visualized with antibodies specific for activated Drice (green). (A) Wild-type testis. Active DRICE is present in multiple elongated cysts. Cystic bulges (cb) and waste bags (wb) are indicated by arrows. (B and C) Teste... |
PMC300883_pbio-0020015-g001_32.jpg | What stands out most in this visual? | Caspase Activity Is Required for Spermatid Individualization(A–C) Testis of different genotypes were visualized with antibodies specific for activated Drice (green). (A) Wild-type testis. Active DRICE is present in multiple elongated cysts. Cystic bulges (cb) and waste bags (wb) are indicated by arrows. (B and C) Teste... |
PMC300883_pbio-0020015-g001_33.jpg | What does this image primarily show? | Caspase Activity Is Required for Spermatid Individualization(A–C) Testis of different genotypes were visualized with antibodies specific for activated Drice (green). (A) Wild-type testis. Active DRICE is present in multiple elongated cysts. Cystic bulges (cb) and waste bags (wb) are indicated by arrows. (B and C) Teste... |
PMC300883_pbio-0020015-g003_47.jpg | What is the principal component of this image? | DRONC Activation Occurs in Association with Individualization Complexes and Is ARK-Dependent(A and B) Wild-type testis stained for active DRICE (green), phalloidin-stained filamentous actin (red), and TOTO-3-stained DNA (blue). (A) Active DRICE is present throughout the length of cysts undergoing individualization. (B)... |
PMC300883_pbio-0020015-g003_44.jpg | Can you identify the primary element in this image? | DRONC Activation Occurs in Association with Individualization Complexes and Is ARK-Dependent(A and B) Wild-type testis stained for active DRICE (green), phalloidin-stained filamentous actin (red), and TOTO-3-stained DNA (blue). (A) Active DRICE is present throughout the length of cysts undergoing individualization. (B)... |
PMC300883_pbio-0020015-g003_49.jpg | Describe the main subject of this image. | DRONC Activation Occurs in Association with Individualization Complexes and Is ARK-Dependent(A and B) Wild-type testis stained for active DRICE (green), phalloidin-stained filamentous actin (red), and TOTO-3-stained DNA (blue). (A) Active DRICE is present throughout the length of cysts undergoing individualization. (B)... |
PMC300883_pbio-0020015-g006_29.jpg | What key item or scene is captured in this photo? |
driceless Males Lack Active Drice Staining and Show Defects in Individualization(A) Testis from driceless male stained with active DRICE. Active DRICE staining is eliminated.(B) Elongated cysts from driceless male. AXO49 staining (blue) outlines the location of three cystic bulges. Individualization complexes (arrows)... |
PMC300883_pbio-0020015-g006_26.jpg | What is the core subject represented in this visual? |
driceless Males Lack Active Drice Staining and Show Defects in Individualization(A) Testis from driceless male stained with active DRICE. Active DRICE staining is eliminated.(B) Elongated cysts from driceless male. AXO49 staining (blue) outlines the location of three cystic bulges. Individualization complexes (arrows)... |
PMC300883_pbio-0020015-g006_28.jpg | What object or scene is depicted here? |
driceless Males Lack Active Drice Staining and Show Defects in Individualization(A) Testis from driceless male stained with active DRICE. Active DRICE staining is eliminated.(B) Elongated cysts from driceless male. AXO49 staining (blue) outlines the location of three cystic bulges. Individualization complexes (arrows)... |
PMC300883_pbio-0020015-g006_25.jpg | What is the focal point of this photograph? |
driceless Males Lack Active Drice Staining and Show Defects in Individualization(A) Testis from driceless male stained with active DRICE. Active DRICE staining is eliminated.(B) Elongated cysts from driceless male. AXO49 staining (blue) outlines the location of three cystic bulges. Individualization complexes (arrows)... |
PMC300883_pbio-0020015-g006_27.jpg | What's the most prominent thing you notice in this picture? |
driceless Males Lack Active Drice Staining and Show Defects in Individualization(A) Testis from driceless male stained with active DRICE. Active DRICE staining is eliminated.(B) Elongated cysts from driceless male. AXO49 staining (blue) outlines the location of three cystic bulges. Individualization complexes (arrows)... |
PMC300883_pbio-0020015-g007_30.jpg | What is shown in this image? | Active DRICE Is Eliminated from the Cytoplasm of Wild-Type Spermatids Following Passage of the Individualization Complex, but Not from Spermatids in Which Caspase Activity Has Been Inhibited(A) Cystic bulge from a wild-type cyst stained with active DRICE (red). The cystic bulge (arrowhead) is moving to the left. Active... |
PMC300883_pbio-0020015-g007_31.jpg | What can you see in this picture? | Active DRICE Is Eliminated from the Cytoplasm of Wild-Type Spermatids Following Passage of the Individualization Complex, but Not from Spermatids in Which Caspase Activity Has Been Inhibited(A) Cystic bulge from a wild-type cyst stained with active DRICE (red). The cystic bulge (arrowhead) is moving to the left. Active... |
PMC314300_pbio-0020007-g005_50.jpg | What's the most prominent thing you notice in this picture? | Histological Architecture of CSR Gene Expression in Breast CancerRepresentative ISH of LOXL2 and SDFR1 and IHC of PLOD2, PLAUR, and ESDN are shown (magnification, 200×). Panels for LOXL2, PLAUR, PLOD2, and ESDN represent cores of normal and invasive ductal breast carcinoma from different patients on the same tissue mic... |
PMC317275_pbio-0020008-g002_74.jpg | What is the central feature of this picture? | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g002_65.jpg | What is shown in this image? | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g002_73.jpg | What is the focal point of this photograph? | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g002_75.jpg | What is the focal point of this photograph? | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g002_67.jpg | What is the core subject represented in this visual? | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g002_68.jpg | What object or scene is depicted here? | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g002_64.jpg | What object or scene is depicted here? | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g002_69.jpg | Describe the main subject of this image. | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g002_72.jpg | What key item or scene is captured in this photo? | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g002_70.jpg | What stands out most in this visual? | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g002_63.jpg | What does this image primarily show? | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g002_76.jpg | What is the dominant medical problem in this image? | Time-Lapse Series of Meiosis Progression in Control, asp, and Colcemid-Treated SpermatocytesTimepoint 0 coincides with the time of NEB revealed by the sudden entry of GFP signal into the nucleus. In control cells (Video 2), microtubules are mainly organised around the centrosomes (arrows). However, when centrosomes are... |
PMC317275_pbio-0020008-g004_59.jpg | What's the most prominent thing you notice in this picture? | The Place of Noncentrosomal Microtubule NucleationThe initial stages of noncentrosomal microtubule nucleation revealed by an endogenous GFP–α-tubulin fusion (left) and phase contrast (right). Following the corresponding videos, it is possible to unmistakably tell the chromosomes (arrows) apart form the other phase-dark... |
PMC317275_pbio-0020008-g004_52.jpg | What is the focal point of this photograph? | The Place of Noncentrosomal Microtubule NucleationThe initial stages of noncentrosomal microtubule nucleation revealed by an endogenous GFP–α-tubulin fusion (left) and phase contrast (right). Following the corresponding videos, it is possible to unmistakably tell the chromosomes (arrows) apart form the other phase-dark... |
PMC317275_pbio-0020008-g004_60.jpg | Can you identify the primary element in this image? | The Place of Noncentrosomal Microtubule NucleationThe initial stages of noncentrosomal microtubule nucleation revealed by an endogenous GFP–α-tubulin fusion (left) and phase contrast (right). Following the corresponding videos, it is possible to unmistakably tell the chromosomes (arrows) apart form the other phase-dark... |
PMC317275_pbio-0020008-g004_55.jpg | What key item or scene is captured in this photo? | The Place of Noncentrosomal Microtubule NucleationThe initial stages of noncentrosomal microtubule nucleation revealed by an endogenous GFP–α-tubulin fusion (left) and phase contrast (right). Following the corresponding videos, it is possible to unmistakably tell the chromosomes (arrows) apart form the other phase-dark... |
PMC317275_pbio-0020008-g004_58.jpg | What is the dominant medical problem in this image? | The Place of Noncentrosomal Microtubule NucleationThe initial stages of noncentrosomal microtubule nucleation revealed by an endogenous GFP–α-tubulin fusion (left) and phase contrast (right). Following the corresponding videos, it is possible to unmistakably tell the chromosomes (arrows) apart form the other phase-dark... |
PMC317275_pbio-0020008-g004_53.jpg | What's the most prominent thing you notice in this picture? | The Place of Noncentrosomal Microtubule NucleationThe initial stages of noncentrosomal microtubule nucleation revealed by an endogenous GFP–α-tubulin fusion (left) and phase contrast (right). Following the corresponding videos, it is possible to unmistakably tell the chromosomes (arrows) apart form the other phase-dark... |
PMC317275_pbio-0020008-g004_57.jpg | What is the core subject represented in this visual? | The Place of Noncentrosomal Microtubule NucleationThe initial stages of noncentrosomal microtubule nucleation revealed by an endogenous GFP–α-tubulin fusion (left) and phase contrast (right). Following the corresponding videos, it is possible to unmistakably tell the chromosomes (arrows) apart form the other phase-dark... |
PMC317275_pbio-0020008-g004_54.jpg | What is the principal component of this image? | The Place of Noncentrosomal Microtubule NucleationThe initial stages of noncentrosomal microtubule nucleation revealed by an endogenous GFP–α-tubulin fusion (left) and phase contrast (right). Following the corresponding videos, it is possible to unmistakably tell the chromosomes (arrows) apart form the other phase-dark... |
PMC317275_pbio-0020008-g004_56.jpg | What is being portrayed in this visual content? | The Place of Noncentrosomal Microtubule NucleationThe initial stages of noncentrosomal microtubule nucleation revealed by an endogenous GFP–α-tubulin fusion (left) and phase contrast (right). Following the corresponding videos, it is possible to unmistakably tell the chromosomes (arrows) apart form the other phase-dark... |
PMC317275_pbio-0020008-g004_61.jpg | What is the dominant medical problem in this image? | The Place of Noncentrosomal Microtubule NucleationThe initial stages of noncentrosomal microtubule nucleation revealed by an endogenous GFP–α-tubulin fusion (left) and phase contrast (right). Following the corresponding videos, it is possible to unmistakably tell the chromosomes (arrows) apart form the other phase-dark... |
PMC317275_pbio-0020008-g006_79.jpg | What is being portrayed in this visual content? | Correlation between the Orientation of the Cytokinesis Furrow, the Asters, and the Spindle in asp SpermatocytesSchematic representation (A–C) of the relative position of the asters (red), the spindle (yellow), and the cytokinesis furrow (blue), corresponding to a control cell (D) and two examples of asp mutant spermato... |
PMC317275_pbio-0020008-g006_78.jpg | What is the core subject represented in this visual? | Correlation between the Orientation of the Cytokinesis Furrow, the Asters, and the Spindle in asp SpermatocytesSchematic representation (A–C) of the relative position of the asters (red), the spindle (yellow), and the cytokinesis furrow (blue), corresponding to a control cell (D) and two examples of asp mutant spermato... |
PMC340949_pbio-0020046-g003_87.jpg | Describe the main subject of this image. | Decreased Fiber CoherenceDecreased fiber coherences, as observed with DTI, in persistent developmental stutterers compared with a fluent control group. A red dot indicates the peak difference in a coronal (top left), axial (top right), and a sagittal (bottom) slice. |
PMC340949_pbio-0020046-g003_86.jpg | What can you see in this picture? | Decreased Fiber CoherenceDecreased fiber coherences, as observed with DTI, in persistent developmental stutterers compared with a fluent control group. A red dot indicates the peak difference in a coronal (top left), axial (top right), and a sagittal (bottom) slice. |
PMC340949_pbio-0020046-g003_85.jpg | What's the most prominent thing you notice in this picture? | Decreased Fiber CoherenceDecreased fiber coherences, as observed with DTI, in persistent developmental stutterers compared with a fluent control group. A red dot indicates the peak difference in a coronal (top left), axial (top right), and a sagittal (bottom) slice. |
PMC340949_pbio-0020046-g003_89.jpg | What does this image primarily show? | Decreased Fiber CoherenceDecreased fiber coherences, as observed with DTI, in persistent developmental stutterers compared with a fluent control group. A red dot indicates the peak difference in a coronal (top left), axial (top right), and a sagittal (bottom) slice. |
PMC387268_pbio-0020097-g002_93.jpg | What is the focal point of this photograph? | FMRI Insight Effect in RH aSTG(A) Voxels showing greater FMRI signal for insight than noninsight solutions, overlaid on the averaged normalized structural image of all subjects. The active area has a volume of 531 mm3 (peak t = 4.89 at 44, −9, −9 in Talairach space).(B) and (C) Group average signal change following the... |
PMC387268_pbio-0020097-g002_94.jpg | What key item or scene is captured in this photo? | FMRI Insight Effect in RH aSTG(A) Voxels showing greater FMRI signal for insight than noninsight solutions, overlaid on the averaged normalized structural image of all subjects. The active area has a volume of 531 mm3 (peak t = 4.89 at 44, −9, −9 in Talairach space).(B) and (C) Group average signal change following the... |
PMC387268_pbio-0020097-g003_96.jpg | What does this image primarily show? | FMRI Signal in RH aSTG during Initial Solving Efforts(A) Voxels in right temporal lobe showing baseline-to-peak event-related FMRI signal when subjects first encounter problems, overlaid on the averaged normalized structural image of all subjects. The cluster is in RH aSTG, with a volume of 469 mm3, with peak t value o... |
PMC406391_pbio-0020129-g001_109.jpg | What stands out most in this visual? | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC406391_pbio-0020129-g001_106.jpg | What is shown in this image? | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC406391_pbio-0020129-g001_108.jpg | What object or scene is depicted here? | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC406391_pbio-0020129-g001_99.jpg | What is the central feature of this picture? | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC406391_pbio-0020129-g001_107.jpg | What key item or scene is captured in this photo? | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC406391_pbio-0020129-g001_101.jpg | What is the dominant medical problem in this image? | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC406391_pbio-0020129-g001_110.jpg | Describe the main subject of this image. | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC406391_pbio-0020129-g001_103.jpg | What's the most prominent thing you notice in this picture? | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC406391_pbio-0020129-g001_104.jpg | What is the central feature of this picture? | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC406391_pbio-0020129-g001_100.jpg | What key item or scene is captured in this photo? | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC406391_pbio-0020129-g001_98.jpg | What key item or scene is captured in this photo? | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC406391_pbio-0020129-g001_105.jpg | What is the dominant medical problem in this image? | Embryos with Defective Myocardial Function Do Not Form AV ECs(A–C) Fluorescence micrographs of embryos carrying a tie2::GFP transgene, visualized at 48 hpf. In (A), the endocardial ring is visible as a collection of GFP-positive cells at the AV boundary in wild-type (wt) embryos (red arrow). In (B), sih−/− embryos fail... |
PMC423138_pbio-0020163-g003_114.jpg | What key item or scene is captured in this photo? | Doxycycline and tTA-Dependent FCIP ExpressionImmunohistochemical assay (A–F) using rabbit polyclonal GFP antibodies/peroxidase-DAB system: (A) YC3.12, single-positive (MTH-YC3.12-7), double-positive (MTH-YC3.12-7, αCamKII-tTA), and Dox-treated double-positive (MTH-YC3.12-7, αCamKII-tTA).(B) Cg2, single-positive (MTH-Cg... |
PMC423138_pbio-0020163-g003_116.jpg | Describe the main subject of this image. | Doxycycline and tTA-Dependent FCIP ExpressionImmunohistochemical assay (A–F) using rabbit polyclonal GFP antibodies/peroxidase-DAB system: (A) YC3.12, single-positive (MTH-YC3.12-7), double-positive (MTH-YC3.12-7, αCamKII-tTA), and Dox-treated double-positive (MTH-YC3.12-7, αCamKII-tTA).(B) Cg2, single-positive (MTH-Cg... |
PMC423138_pbio-0020163-g003_117.jpg | What is being portrayed in this visual content? | Doxycycline and tTA-Dependent FCIP ExpressionImmunohistochemical assay (A–F) using rabbit polyclonal GFP antibodies/peroxidase-DAB system: (A) YC3.12, single-positive (MTH-YC3.12-7), double-positive (MTH-YC3.12-7, αCamKII-tTA), and Dox-treated double-positive (MTH-YC3.12-7, αCamKII-tTA).(B) Cg2, single-positive (MTH-Cg... |
PMC423141_pbio-0020167-g002_122.jpg | What is the principal component of this image? | Mutant α-Actinin-4 Behavior in Cells(A) Mutant and wild-type α-actinin-4 show different localization and dynamics when expressed in a conditionally immortalized differentiated mouse podocyte cell line. Differentiated podocytes were injected in the nucleus with equal concentrations of expression plasmid for GFP fusions ... |
PMC423141_pbio-0020167-g002_121.jpg | What stands out most in this visual? | Mutant α-Actinin-4 Behavior in Cells(A) Mutant and wild-type α-actinin-4 show different localization and dynamics when expressed in a conditionally immortalized differentiated mouse podocyte cell line. Differentiated podocytes were injected in the nucleus with equal concentrations of expression plasmid for GFP fusions ... |
PMC423141_pbio-0020167-g002_124.jpg | What is shown in this image? | Mutant α-Actinin-4 Behavior in Cells(A) Mutant and wild-type α-actinin-4 show different localization and dynamics when expressed in a conditionally immortalized differentiated mouse podocyte cell line. Differentiated podocytes were injected in the nucleus with equal concentrations of expression plasmid for GFP fusions ... |
PMC423141_pbio-0020167-g002_128.jpg | What can you see in this picture? | Mutant α-Actinin-4 Behavior in Cells(A) Mutant and wild-type α-actinin-4 show different localization and dynamics when expressed in a conditionally immortalized differentiated mouse podocyte cell line. Differentiated podocytes were injected in the nucleus with equal concentrations of expression plasmid for GFP fusions ... |
PMC423141_pbio-0020167-g002_129.jpg | What is the core subject represented in this visual? | Mutant α-Actinin-4 Behavior in Cells(A) Mutant and wild-type α-actinin-4 show different localization and dynamics when expressed in a conditionally immortalized differentiated mouse podocyte cell line. Differentiated podocytes were injected in the nucleus with equal concentrations of expression plasmid for GFP fusions ... |
PMC449784_pbio-0020158-g003_138.jpg | What is the core subject represented in this visual? | GOF Planar Polarity Wing Phenotype of Fz1/2 Chimeras
dpp-Gal4 was used to express the respective Fz1/2 chimeras in the wing (same as described in Figure 2).(A) Wild-type wing. The dpp-Gal4 expression domain is highlighted by a thick orange line. In wild-type, all wing hairs are pointing distally.(B) dpp-Gal4; UAS-EGFP/... |
PMC449784_pbio-0020158-g003_136.jpg | What is the main focus of this visual representation? | GOF Planar Polarity Wing Phenotype of Fz1/2 Chimeras
dpp-Gal4 was used to express the respective Fz1/2 chimeras in the wing (same as described in Figure 2).(A) Wild-type wing. The dpp-Gal4 expression domain is highlighted by a thick orange line. In wild-type, all wing hairs are pointing distally.(B) dpp-Gal4; UAS-EGFP/... |
PMC449784_pbio-0020158-g003_139.jpg | What is the dominant medical problem in this image? | GOF Planar Polarity Wing Phenotype of Fz1/2 Chimeras
dpp-Gal4 was used to express the respective Fz1/2 chimeras in the wing (same as described in Figure 2).(A) Wild-type wing. The dpp-Gal4 expression domain is highlighted by a thick orange line. In wild-type, all wing hairs are pointing distally.(B) dpp-Gal4; UAS-EGFP/... |
PMC449784_pbio-0020158-g003_134.jpg | What object or scene is depicted here? | GOF Planar Polarity Wing Phenotype of Fz1/2 Chimeras
dpp-Gal4 was used to express the respective Fz1/2 chimeras in the wing (same as described in Figure 2).(A) Wild-type wing. The dpp-Gal4 expression domain is highlighted by a thick orange line. In wild-type, all wing hairs are pointing distally.(B) dpp-Gal4; UAS-EGFP/... |
PMC449784_pbio-0020158-g003_137.jpg | What is the focal point of this photograph? | GOF Planar Polarity Wing Phenotype of Fz1/2 Chimeras
dpp-Gal4 was used to express the respective Fz1/2 chimeras in the wing (same as described in Figure 2).(A) Wild-type wing. The dpp-Gal4 expression domain is highlighted by a thick orange line. In wild-type, all wing hairs are pointing distally.(B) dpp-Gal4; UAS-EGFP/... |
PMC449821_pbio-0020178-g009_140.jpg | Can you identify the primary element in this image? | Hairy Shows Context-Dependent Association with Its Cofactors(A) Sites of Hairy binding and Hairy cofactor recruitment based on DamID. The gray lines depict the relative position on the chromosomes of the approximately 6200 cDNAs on the microarray chip. The blue dots below the line represent Hairy binding sites while th... |
PMC449821_pbio-0020178-g009_146.jpg | What is the principal component of this image? | Hairy Shows Context-Dependent Association with Its Cofactors(A) Sites of Hairy binding and Hairy cofactor recruitment based on DamID. The gray lines depict the relative position on the chromosomes of the approximately 6200 cDNAs on the microarray chip. The blue dots below the line represent Hairy binding sites while th... |
PMC449821_pbio-0020178-g009_144.jpg | What is the focal point of this photograph? | Hairy Shows Context-Dependent Association with Its Cofactors(A) Sites of Hairy binding and Hairy cofactor recruitment based on DamID. The gray lines depict the relative position on the chromosomes of the approximately 6200 cDNAs on the microarray chip. The blue dots below the line represent Hairy binding sites while th... |
PMC449870_pbio-0020207-g003_148.jpg | What is shown in this image? | FISH Confirmation of a Human-Specific Duplication of a Gene Cluster on Chromosome 5q13.3 Detected by Interspecies cDNA aCGH(A) Human duplication of a cluster of genes at Chromosome 5q13.3. is shown by two separate, and sometimes multiple, red BAC probe (CTD-2288G5) signals in interphase cells, with only one green BAC p... |
PMC449870_pbio-0020207-g003_149.jpg | What's the most prominent thing you notice in this picture? | FISH Confirmation of a Human-Specific Duplication of a Gene Cluster on Chromosome 5q13.3 Detected by Interspecies cDNA aCGH(A) Human duplication of a cluster of genes at Chromosome 5q13.3. is shown by two separate, and sometimes multiple, red BAC probe (CTD-2288G5) signals in interphase cells, with only one green BAC p... |
PMC449870_pbio-0020207-g003_150.jpg | What is the main focus of this visual representation? | FISH Confirmation of a Human-Specific Duplication of a Gene Cluster on Chromosome 5q13.3 Detected by Interspecies cDNA aCGH(A) Human duplication of a cluster of genes at Chromosome 5q13.3. is shown by two separate, and sometimes multiple, red BAC probe (CTD-2288G5) signals in interphase cells, with only one green BAC p... |
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