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PMC514490_pbio-0020261-g009_278.jpg
What stands out most in this visual?
Immunolocalisation of Rabankyrin-5 in the Mouse KidneyMouse kidney cortex was processed for frozen section immunoelectron microscopy. Sections were (A and B) single labelled for Rabankyrin-5 (arrowheads, 10 nm) or (C and D) double labelled (arrows, 5 nm) for Rabankyrin-5 and LAMP-1.(A) Low-magnification view of the api...
PMC514499_F4_283.jpg
What is the central feature of this picture?
Echocardiographic apical four-chamber images (end-systolic frames) from two patients with and without contractile reserve.
PMC514499_F4_286.jpg
What object or scene is depicted here?
Echocardiographic apical four-chamber images (end-systolic frames) from two patients with and without contractile reserve.
PMC514499_F4_282.jpg
What stands out most in this visual?
Echocardiographic apical four-chamber images (end-systolic frames) from two patients with and without contractile reserve.
PMC514525_F1_290.jpg
What stands out most in this visual?
US of 65 years old male presented to emergency room with bilateral flank pain, nausea and vomiting for the past 1 week. He had an ultrasound in a peripheral hospital, which identified hydronephrosis on the right side, and percutaneous nephrostomy tube was placed. His left kidney showed hydronephrosis with renal stone (...
PMC514525_F1_289.jpg
What does this image primarily show?
US of 65 years old male presented to emergency room with bilateral flank pain, nausea and vomiting for the past 1 week. He had an ultrasound in a peripheral hospital, which identified hydronephrosis on the right side, and percutaneous nephrostomy tube was placed. His left kidney showed hydronephrosis with renal stone (...
PMC514525_F1_288.jpg
Describe the main subject of this image.
US of 65 years old male presented to emergency room with bilateral flank pain, nausea and vomiting for the past 1 week. He had an ultrasound in a peripheral hospital, which identified hydronephrosis on the right side, and percutaneous nephrostomy tube was placed. His left kidney showed hydronephrosis with renal stone (...
PMC514537_pbio-0020288-g007_294.jpg
Can you identify the primary element in this image?
Increased Muscle Damage in HIF-1α KOs Following Repeated Exercise(A) WT mice and HIF-1α KOs underwent a 4-d endurance test, in which animals were run to exhaustion on each of four successive days with a minimum of 22 h rest between trials. HIF-1α KOs demonstrated initially greater endurance under the protocol; however,...
PMC514537_pbio-0020288-g007_291.jpg
Can you identify the primary element in this image?
Increased Muscle Damage in HIF-1α KOs Following Repeated Exercise(A) WT mice and HIF-1α KOs underwent a 4-d endurance test, in which animals were run to exhaustion on each of four successive days with a minimum of 22 h rest between trials. HIF-1α KOs demonstrated initially greater endurance under the protocol; however,...
PMC514537_pbio-0020288-g007_295.jpg
What is being portrayed in this visual content?
Increased Muscle Damage in HIF-1α KOs Following Repeated Exercise(A) WT mice and HIF-1α KOs underwent a 4-d endurance test, in which animals were run to exhaustion on each of four successive days with a minimum of 22 h rest between trials. HIF-1α KOs demonstrated initially greater endurance under the protocol; however,...
PMC514537_pbio-0020288-g007_292.jpg
What does this image primarily show?
Increased Muscle Damage in HIF-1α KOs Following Repeated Exercise(A) WT mice and HIF-1α KOs underwent a 4-d endurance test, in which animals were run to exhaustion on each of four successive days with a minimum of 22 h rest between trials. HIF-1α KOs demonstrated initially greater endurance under the protocol; however,...
PMC514603_F2_300.jpg
What key item or scene is captured in this photo?
Cytotoxicity and OAS1 induction with RNAi vectors. In A, morphology was observed using phase contrast microscopy of non-transduced IS-1 cells, or cells six days after transduction with vectors leading to expression of no shRNA (U6PT), a 25 mer shRNA targeting PAI-2 (sh325) and a scrambled 25 mer control shRNA (sh325scr...
PMC514603_F2_298.jpg
What is being portrayed in this visual content?
Cytotoxicity and OAS1 induction with RNAi vectors. In A, morphology was observed using phase contrast microscopy of non-transduced IS-1 cells, or cells six days after transduction with vectors leading to expression of no shRNA (U6PT), a 25 mer shRNA targeting PAI-2 (sh325) and a scrambled 25 mer control shRNA (sh325scr...
PMC514603_F2_299.jpg
What's the most prominent thing you notice in this picture?
Cytotoxicity and OAS1 induction with RNAi vectors. In A, morphology was observed using phase contrast microscopy of non-transduced IS-1 cells, or cells six days after transduction with vectors leading to expression of no shRNA (U6PT), a 25 mer shRNA targeting PAI-2 (sh325) and a scrambled 25 mer control shRNA (sh325scr...
PMC514603_F2_297.jpg
What is the main focus of this visual representation?
Cytotoxicity and OAS1 induction with RNAi vectors. In A, morphology was observed using phase contrast microscopy of non-transduced IS-1 cells, or cells six days after transduction with vectors leading to expression of no shRNA (U6PT), a 25 mer shRNA targeting PAI-2 (sh325) and a scrambled 25 mer control shRNA (sh325scr...
PMC514604_F1_303.jpg
What does this image primarily show?
CS17 OPT model (a). still shot from movie of 3D OPT model of a CS17 human embryo (approximately 41 days of development). bv, blood vessel; drg, dorsal root ganglion; h, heart; H, hindbrain; l, liver; T, telencephalon; v, vertebrae. (b; Additional file 1) Mpeg movie of 3D CS17 OPT model.
PMC514604_F3_307.jpg
What's the most prominent thing you notice in this picture?
Painted anatomical domains. Fourteen regions of the central nervous system in the CS17 specimen have been defined and painted. Forebrain, red (secondary prosencephalon), dark orange (prosomere 3 including ventral thalamus), light orange (prosomere 2 including dorsal thalamus) and yellow (prosomere 1 including pretectum...
PMC514604_F5_305.jpg
What is the core subject represented in this visual?
3 dimensional gene expression domains. A surface rendered model of the 3D expression pattern of PAX6. Separate gene expression domains in the forebrain and hindbrain are shown in green. For reference the neural tube has been painted pale grey and the eye dark grey. The diencephalon/midbrain (D/M) boundary, the absence ...
PMC514604_F5_304.jpg
What is the core subject represented in this visual?
3 dimensional gene expression domains. A surface rendered model of the 3D expression pattern of PAX6. Separate gene expression domains in the forebrain and hindbrain are shown in green. For reference the neural tube has been painted pale grey and the eye dark grey. The diencephalon/midbrain (D/M) boundary, the absence ...
PMC514614_F7_308.jpg
What is the main focus of this visual representation?
Biopsy form grafted area of the lower eyelid. Hematoxylene-eosin staining, × 100 magnification.
PMC514615_F1_309.jpg
What is the dominant medical problem in this image?
(a) Duodenoscopy showing a 3 × 3 cm protruding tumor with two ulcerations located opposite the ampulla of Vater in the second portion of the duodenum. (b) Hypotonic duodenography showing the donuts-shape tumor in the duodenum.
PMC514615_F1_310.jpg
What key item or scene is captured in this photo?
(a) Duodenoscopy showing a 3 × 3 cm protruding tumor with two ulcerations located opposite the ampulla of Vater in the second portion of the duodenum. (b) Hypotonic duodenography showing the donuts-shape tumor in the duodenum.
PMC514615_F2_311.jpg
What is the main focus of this visual representation?
Macroscopic and microscopic findings of the tumor. (a) Gross appearance of the tumor. The tumor was divided into two components, component A (round shape) and B (crescent shape). (b) Photomicrograph of the gross appearance of the tumor (Hematoxylin and eosin X 2). (c) Photomicrograph of the component A showing fibrous ...
PMC514615_F2_312.jpg
Describe the main subject of this image.
Macroscopic and microscopic findings of the tumor. (a) Gross appearance of the tumor. The tumor was divided into two components, component A (round shape) and B (crescent shape). (b) Photomicrograph of the gross appearance of the tumor (Hematoxylin and eosin X 2). (c) Photomicrograph of the component A showing fibrous ...
PMC514652_F4_315.jpg
What object or scene is depicted here?
Computational models of wild type S1P4 and its E3.29(122)Q mutant with S1P and LPA species. Computational models of the complexes between the wild type S1P4 or its E3.29(122)Q mutant with S1P or various LPA species generated by Autodock 3.0 and minimised using the MMFF94 forcefield in the MOE program. Complexes in each...
PMC514652_F4_314.jpg
What's the most prominent thing you notice in this picture?
Computational models of wild type S1P4 and its E3.29(122)Q mutant with S1P and LPA species. Computational models of the complexes between the wild type S1P4 or its E3.29(122)Q mutant with S1P or various LPA species generated by Autodock 3.0 and minimised using the MMFF94 forcefield in the MOE program. Complexes in each...
PMC514703_F4_322.jpg
What is the dominant medical problem in this image?
Expression pattern of a bas-1::GFP reporter fusion in transgenic Roller worms. (Panels A-C are from the same adult hermaphrodite. Ventral is down and anterior to the right.) A. Ventral, slightly oblique view of the head, showing NSMs, CEPDs, ADEL and likely AIMs. B. Same head, higher (more dorsal) focal plane, showing ...
PMC514703_F4_319.jpg
Describe the main subject of this image.
Expression pattern of a bas-1::GFP reporter fusion in transgenic Roller worms. (Panels A-C are from the same adult hermaphrodite. Ventral is down and anterior to the right.) A. Ventral, slightly oblique view of the head, showing NSMs, CEPDs, ADEL and likely AIMs. B. Same head, higher (more dorsal) focal plane, showing ...
PMC514703_F4_323.jpg
What stands out most in this visual?
Expression pattern of a bas-1::GFP reporter fusion in transgenic Roller worms. (Panels A-C are from the same adult hermaphrodite. Ventral is down and anterior to the right.) A. Ventral, slightly oblique view of the head, showing NSMs, CEPDs, ADEL and likely AIMs. B. Same head, higher (more dorsal) focal plane, showing ...
PMC514703_F4_320.jpg
What is the focal point of this photograph?
Expression pattern of a bas-1::GFP reporter fusion in transgenic Roller worms. (Panels A-C are from the same adult hermaphrodite. Ventral is down and anterior to the right.) A. Ventral, slightly oblique view of the head, showing NSMs, CEPDs, ADEL and likely AIMs. B. Same head, higher (more dorsal) focal plane, showing ...
PMC514711_F2_329.jpg
What key item or scene is captured in this photo?
In-frame <EYOR> transposition events in the voltage sensitive integral membrane motor protein, Prestin. Visual screening of transiently transfected HEK-293 cells revealed truncated Prestin-YFP fusion proteins generated by in-frame <EYOR> transpositions (A) (scale bar = 20 μm). Alternate digestion and re-ligation of an ...
PMC514711_F2_330.jpg
What is the core subject represented in this visual?
In-frame <EYOR> transposition events in the voltage sensitive integral membrane motor protein, Prestin. Visual screening of transiently transfected HEK-293 cells revealed truncated Prestin-YFP fusion proteins generated by in-frame <EYOR> transpositions (A) (scale bar = 20 μm). Alternate digestion and re-ligation of an ...
PMC514711_F3_327.jpg
What is being portrayed in this visual content?
Transposition of the type 1 IP3R with the Double Barrel Transposon (<DBT>). Transient expression in HEK-293 cells allows identification of in-frame insertions producing truncated GFP- (A) or DsRed- (B) IP3R fusion proteins. Digestion and subsequent re-ligation produces a full-length fluorescent IP3R fusion protein (C) ...
PMC514711_F3_328.jpg
Can you identify the primary element in this image?
Transposition of the type 1 IP3R with the Double Barrel Transposon (<DBT>). Transient expression in HEK-293 cells allows identification of in-frame insertions producing truncated GFP- (A) or DsRed- (B) IP3R fusion proteins. Digestion and subsequent re-ligation produces a full-length fluorescent IP3R fusion protein (C) ...
PMC514711_F3_326.jpg
What stands out most in this visual?
Transposition of the type 1 IP3R with the Double Barrel Transposon (<DBT>). Transient expression in HEK-293 cells allows identification of in-frame insertions producing truncated GFP- (A) or DsRed- (B) IP3R fusion proteins. Digestion and subsequent re-ligation produces a full-length fluorescent IP3R fusion protein (C) ...
PMC514717_F2_336.jpg
What does this image primarily show?
Intracellular transport of endocytosed ligands. Cultures of LSEC were pulsed with both TRITC-FSA and FITC-AGG for 1 h at 4°C. Chasing was performed after removal of unbound ligand by washing, and transferring of the cultures to 37°C. The cultures were fixed after chase periods of 10 min or 2 h and examined in fluoresce...
PMC514717_F2_339.jpg
Can you identify the primary element in this image?
Intracellular transport of endocytosed ligands. Cultures of LSEC were pulsed with both TRITC-FSA and FITC-AGG for 1 h at 4°C. Chasing was performed after removal of unbound ligand by washing, and transferring of the cultures to 37°C. The cultures were fixed after chase periods of 10 min or 2 h and examined in fluoresce...
PMC514717_F2_341.jpg
What key item or scene is captured in this photo?
Intracellular transport of endocytosed ligands. Cultures of LSEC were pulsed with both TRITC-FSA and FITC-AGG for 1 h at 4°C. Chasing was performed after removal of unbound ligand by washing, and transferring of the cultures to 37°C. The cultures were fixed after chase periods of 10 min or 2 h and examined in fluoresce...
PMC514717_F2_343.jpg
What key item or scene is captured in this photo?
Intracellular transport of endocytosed ligands. Cultures of LSEC were pulsed with both TRITC-FSA and FITC-AGG for 1 h at 4°C. Chasing was performed after removal of unbound ligand by washing, and transferring of the cultures to 37°C. The cultures were fixed after chase periods of 10 min or 2 h and examined in fluoresce...
PMC514717_F2_344.jpg
Can you identify the primary element in this image?
Intracellular transport of endocytosed ligands. Cultures of LSEC were pulsed with both TRITC-FSA and FITC-AGG for 1 h at 4°C. Chasing was performed after removal of unbound ligand by washing, and transferring of the cultures to 37°C. The cultures were fixed after chase periods of 10 min or 2 h and examined in fluoresce...
PMC514717_F2_340.jpg
Describe the main subject of this image.
Intracellular transport of endocytosed ligands. Cultures of LSEC were pulsed with both TRITC-FSA and FITC-AGG for 1 h at 4°C. Chasing was performed after removal of unbound ligand by washing, and transferring of the cultures to 37°C. The cultures were fixed after chase periods of 10 min or 2 h and examined in fluoresce...
PMC514717_F2_335.jpg
What is being portrayed in this visual content?
Intracellular transport of endocytosed ligands. Cultures of LSEC were pulsed with both TRITC-FSA and FITC-AGG for 1 h at 4°C. Chasing was performed after removal of unbound ligand by washing, and transferring of the cultures to 37°C. The cultures were fixed after chase periods of 10 min or 2 h and examined in fluoresce...
PMC514717_F2_342.jpg
What is the principal component of this image?
Intracellular transport of endocytosed ligands. Cultures of LSEC were pulsed with both TRITC-FSA and FITC-AGG for 1 h at 4°C. Chasing was performed after removal of unbound ligand by washing, and transferring of the cultures to 37°C. The cultures were fixed after chase periods of 10 min or 2 h and examined in fluoresce...
PMC514718_F2_333.jpg
Describe the main subject of this image.
Echocardiography (45 months) long axis view. Myxoma in the left atrium prolapsing into the left ventricle. LV = left ventricle, My = myxoma
PMC514718_F5_334.jpg
What object or scene is depicted here?
Right coronary artery (RCA) in 60 degree LAO position (45 months, pre-operative coronary angiography). White arrow = atypical vessels in the interatrial septum
PMC514883_pbio-0020257-g010_346.jpg
What key item or scene is captured in this photo?
The Expressions of elo-5 and lpd-1 Reporter Constructs Are Spatially Similar(A and B) Nomarski and GFP-filtered images of an adult animal containing the lpd-1Prom::GFP construct, showing strong expression in two symmetrical head neurons, each of which has processes to the nose and around a nerve ring. Scale bars, 10 μm...
PMC514883_pbio-0020257-g010_350.jpg
What is the focal point of this photograph?
The Expressions of elo-5 and lpd-1 Reporter Constructs Are Spatially Similar(A and B) Nomarski and GFP-filtered images of an adult animal containing the lpd-1Prom::GFP construct, showing strong expression in two symmetrical head neurons, each of which has processes to the nose and around a nerve ring. Scale bars, 10 μm...
PMC514883_pbio-0020257-g010_345.jpg
What is being portrayed in this visual content?
The Expressions of elo-5 and lpd-1 Reporter Constructs Are Spatially Similar(A and B) Nomarski and GFP-filtered images of an adult animal containing the lpd-1Prom::GFP construct, showing strong expression in two symmetrical head neurons, each of which has processes to the nose and around a nerve ring. Scale bars, 10 μm...
PMC514883_pbio-0020257-g010_351.jpg
What is the core subject represented in this visual?
The Expressions of elo-5 and lpd-1 Reporter Constructs Are Spatially Similar(A and B) Nomarski and GFP-filtered images of an adult animal containing the lpd-1Prom::GFP construct, showing strong expression in two symmetrical head neurons, each of which has processes to the nose and around a nerve ring. Scale bars, 10 μm...
PMC514883_pbio-0020257-g010_349.jpg
What is the principal component of this image?
The Expressions of elo-5 and lpd-1 Reporter Constructs Are Spatially Similar(A and B) Nomarski and GFP-filtered images of an adult animal containing the lpd-1Prom::GFP construct, showing strong expression in two symmetrical head neurons, each of which has processes to the nose and around a nerve ring. Scale bars, 10 μm...
PMC514883_pbio-0020257-g011_355.jpg
What is being portrayed in this visual content?
The Expression of GFP Fusion Constructs Suggests the Involvement of lpd-1, acs-1, and pnk-1 in mmBCFA Biosynthesis(A–D) elo-5Prom::GFP expression is downregulated in the lpd-1(RNAi) background. Scale bars, 100 μm.(A and C) GFP-filtered images of (A) elo-5Prom::GFP and (C) elo-6Prom::GFP in wild-type animals, showing th...
PMC514883_pbio-0020257-g011_359.jpg
What is being portrayed in this visual content?
The Expression of GFP Fusion Constructs Suggests the Involvement of lpd-1, acs-1, and pnk-1 in mmBCFA Biosynthesis(A–D) elo-5Prom::GFP expression is downregulated in the lpd-1(RNAi) background. Scale bars, 100 μm.(A and C) GFP-filtered images of (A) elo-5Prom::GFP and (C) elo-6Prom::GFP in wild-type animals, showing th...
PMC514883_pbio-0020257-g011_353.jpg
What key item or scene is captured in this photo?
The Expression of GFP Fusion Constructs Suggests the Involvement of lpd-1, acs-1, and pnk-1 in mmBCFA Biosynthesis(A–D) elo-5Prom::GFP expression is downregulated in the lpd-1(RNAi) background. Scale bars, 100 μm.(A and C) GFP-filtered images of (A) elo-5Prom::GFP and (C) elo-6Prom::GFP in wild-type animals, showing th...
PMC514883_pbio-0020257-g011_365.jpg
What is shown in this image?
The Expression of GFP Fusion Constructs Suggests the Involvement of lpd-1, acs-1, and pnk-1 in mmBCFA Biosynthesis(A–D) elo-5Prom::GFP expression is downregulated in the lpd-1(RNAi) background. Scale bars, 100 μm.(A and C) GFP-filtered images of (A) elo-5Prom::GFP and (C) elo-6Prom::GFP in wild-type animals, showing th...
PMC514883_pbio-0020257-g011_366.jpg
What does this image primarily show?
The Expression of GFP Fusion Constructs Suggests the Involvement of lpd-1, acs-1, and pnk-1 in mmBCFA Biosynthesis(A–D) elo-5Prom::GFP expression is downregulated in the lpd-1(RNAi) background. Scale bars, 100 μm.(A and C) GFP-filtered images of (A) elo-5Prom::GFP and (C) elo-6Prom::GFP in wild-type animals, showing th...
PMC514883_pbio-0020257-g011_364.jpg
What is the central feature of this picture?
The Expression of GFP Fusion Constructs Suggests the Involvement of lpd-1, acs-1, and pnk-1 in mmBCFA Biosynthesis(A–D) elo-5Prom::GFP expression is downregulated in the lpd-1(RNAi) background. Scale bars, 100 μm.(A and C) GFP-filtered images of (A) elo-5Prom::GFP and (C) elo-6Prom::GFP in wild-type animals, showing th...
PMC514883_pbio-0020257-g011_361.jpg
What stands out most in this visual?
The Expression of GFP Fusion Constructs Suggests the Involvement of lpd-1, acs-1, and pnk-1 in mmBCFA Biosynthesis(A–D) elo-5Prom::GFP expression is downregulated in the lpd-1(RNAi) background. Scale bars, 100 μm.(A and C) GFP-filtered images of (A) elo-5Prom::GFP and (C) elo-6Prom::GFP in wild-type animals, showing th...
PMC514883_pbio-0020257-g011_362.jpg
What is the focal point of this photograph?
The Expression of GFP Fusion Constructs Suggests the Involvement of lpd-1, acs-1, and pnk-1 in mmBCFA Biosynthesis(A–D) elo-5Prom::GFP expression is downregulated in the lpd-1(RNAi) background. Scale bars, 100 μm.(A and C) GFP-filtered images of (A) elo-5Prom::GFP and (C) elo-6Prom::GFP in wild-type animals, showing th...
PMC514883_pbio-0020257-g011_358.jpg
What is the dominant medical problem in this image?
The Expression of GFP Fusion Constructs Suggests the Involvement of lpd-1, acs-1, and pnk-1 in mmBCFA Biosynthesis(A–D) elo-5Prom::GFP expression is downregulated in the lpd-1(RNAi) background. Scale bars, 100 μm.(A and C) GFP-filtered images of (A) elo-5Prom::GFP and (C) elo-6Prom::GFP in wild-type animals, showing th...
PMC514883_pbio-0020257-g011_354.jpg
Can you identify the primary element in this image?
The Expression of GFP Fusion Constructs Suggests the Involvement of lpd-1, acs-1, and pnk-1 in mmBCFA Biosynthesis(A–D) elo-5Prom::GFP expression is downregulated in the lpd-1(RNAi) background. Scale bars, 100 μm.(A and C) GFP-filtered images of (A) elo-5Prom::GFP and (C) elo-6Prom::GFP in wild-type animals, showing th...
PMC514883_pbio-0020257-g011_363.jpg
What is the main focus of this visual representation?
The Expression of GFP Fusion Constructs Suggests the Involvement of lpd-1, acs-1, and pnk-1 in mmBCFA Biosynthesis(A–D) elo-5Prom::GFP expression is downregulated in the lpd-1(RNAi) background. Scale bars, 100 μm.(A and C) GFP-filtered images of (A) elo-5Prom::GFP and (C) elo-6Prom::GFP in wild-type animals, showing th...
PMC515295_F3_368.jpg
What key item or scene is captured in this photo?
pY504-C3G colocalizes with Hck and shows predominant Golgi and membrane localization. (A) pY504 C3G colocalizes with Hck. Cos-1 cells transfected with Hck and C3G were stained for pY504 C3G (Cy3) and Hck (FITC) and examined using a confocal microscope. Figure shows an optical section for the individual stains as well a...
PMC515295_F3_369.jpg
What is the dominant medical problem in this image?
pY504-C3G colocalizes with Hck and shows predominant Golgi and membrane localization. (A) pY504 C3G colocalizes with Hck. Cos-1 cells transfected with Hck and C3G were stained for pY504 C3G (Cy3) and Hck (FITC) and examined using a confocal microscope. Figure shows an optical section for the individual stains as well a...
PMC515295_F3_373.jpg
What does this image primarily show?
pY504-C3G colocalizes with Hck and shows predominant Golgi and membrane localization. (A) pY504 C3G colocalizes with Hck. Cos-1 cells transfected with Hck and C3G were stained for pY504 C3G (Cy3) and Hck (FITC) and examined using a confocal microscope. Figure shows an optical section for the individual stains as well a...
PMC515295_F3_370.jpg
What can you see in this picture?
pY504-C3G colocalizes with Hck and shows predominant Golgi and membrane localization. (A) pY504 C3G colocalizes with Hck. Cos-1 cells transfected with Hck and C3G were stained for pY504 C3G (Cy3) and Hck (FITC) and examined using a confocal microscope. Figure shows an optical section for the individual stains as well a...
PMC515295_F3_372.jpg
What is the main focus of this visual representation?
pY504-C3G colocalizes with Hck and shows predominant Golgi and membrane localization. (A) pY504 C3G colocalizes with Hck. Cos-1 cells transfected with Hck and C3G were stained for pY504 C3G (Cy3) and Hck (FITC) and examined using a confocal microscope. Figure shows an optical section for the individual stains as well a...
PMC515295_F3_371.jpg
What is the dominant medical problem in this image?
pY504-C3G colocalizes with Hck and shows predominant Golgi and membrane localization. (A) pY504 C3G colocalizes with Hck. Cos-1 cells transfected with Hck and C3G were stained for pY504 C3G (Cy3) and Hck (FITC) and examined using a confocal microscope. Figure shows an optical section for the individual stains as well a...
PMC516018_F2_378.jpg
What is being portrayed in this visual content?
Distribution of keratin IFs and HSP70i in hepatocytes from control and GF-fed C3H mice. A, C, E keratin IFs; B, D, F HSP70i; A, B) control; C, D) 2 week treatment; E, F) 5 month treatment. Arrows in E and F indicate reactive MBs with Troma 1 (anti-K8) and anti-HSP70i, respectively. Scale bar = 20 μm.
PMC516018_F2_379.jpg
What is the main focus of this visual representation?
Distribution of keratin IFs and HSP70i in hepatocytes from control and GF-fed C3H mice. A, C, E keratin IFs; B, D, F HSP70i; A, B) control; C, D) 2 week treatment; E, F) 5 month treatment. Arrows in E and F indicate reactive MBs with Troma 1 (anti-K8) and anti-HSP70i, respectively. Scale bar = 20 μm.
PMC516018_F2_383.jpg
Can you identify the primary element in this image?
Distribution of keratin IFs and HSP70i in hepatocytes from control and GF-fed C3H mice. A, C, E keratin IFs; B, D, F HSP70i; A, B) control; C, D) 2 week treatment; E, F) 5 month treatment. Arrows in E and F indicate reactive MBs with Troma 1 (anti-K8) and anti-HSP70i, respectively. Scale bar = 20 μm.
PMC516018_F2_380.jpg
Can you identify the primary element in this image?
Distribution of keratin IFs and HSP70i in hepatocytes from control and GF-fed C3H mice. A, C, E keratin IFs; B, D, F HSP70i; A, B) control; C, D) 2 week treatment; E, F) 5 month treatment. Arrows in E and F indicate reactive MBs with Troma 1 (anti-K8) and anti-HSP70i, respectively. Scale bar = 20 μm.
PMC516018_F3_400.jpg
What is shown in this image?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, F, I keratin IFs; B, D, E, G, H, J K8 pS79; A, B) control; C, D, E) 2 week treatment; F, G, H 6 week treatment; I, J 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79. Empty arrowheads in I and J in...
PMC516018_F3_401.jpg
What is the central feature of this picture?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, F, I keratin IFs; B, D, E, G, H, J K8 pS79; A, B) control; C, D, E) 2 week treatment; F, G, H 6 week treatment; I, J 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79. Empty arrowheads in I and J in...
PMC516018_F3_404.jpg
What does this image primarily show?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, F, I keratin IFs; B, D, E, G, H, J K8 pS79; A, B) control; C, D, E) 2 week treatment; F, G, H 6 week treatment; I, J 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79. Empty arrowheads in I and J in...
PMC516018_F3_402.jpg
What object or scene is depicted here?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, F, I keratin IFs; B, D, E, G, H, J K8 pS79; A, B) control; C, D, E) 2 week treatment; F, G, H 6 week treatment; I, J 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79. Empty arrowheads in I and J in...
PMC516018_F3_409.jpg
What stands out most in this visual?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, F, I keratin IFs; B, D, E, G, H, J K8 pS79; A, B) control; C, D, E) 2 week treatment; F, G, H 6 week treatment; I, J 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79. Empty arrowheads in I and J in...
PMC516018_F3_408.jpg
What is the focal point of this photograph?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, F, I keratin IFs; B, D, E, G, H, J K8 pS79; A, B) control; C, D, E) 2 week treatment; F, G, H 6 week treatment; I, J 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79. Empty arrowheads in I and J in...
PMC516018_F3_406.jpg
What is the main focus of this visual representation?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, F, I keratin IFs; B, D, E, G, H, J K8 pS79; A, B) control; C, D, E) 2 week treatment; F, G, H 6 week treatment; I, J 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79. Empty arrowheads in I and J in...
PMC516018_F3_405.jpg
What can you see in this picture?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, F, I keratin IFs; B, D, E, G, H, J K8 pS79; A, B) control; C, D, E) 2 week treatment; F, G, H 6 week treatment; I, J 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79. Empty arrowheads in I and J in...
PMC516018_F4_396.jpg
What's the most prominent thing you notice in this picture?
Distribution of keratin IFs and K8 pS436 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS436; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H); 5 month treatment. Arrows in D indicate clusters of cells containing K8 pS436. Filled arrowheads in G and H indicat...
PMC516018_F4_397.jpg
What is the central feature of this picture?
Distribution of keratin IFs and K8 pS436 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS436; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H); 5 month treatment. Arrows in D indicate clusters of cells containing K8 pS436. Filled arrowheads in G and H indicat...
PMC516018_F4_392.jpg
What is the focal point of this photograph?
Distribution of keratin IFs and K8 pS436 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS436; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H); 5 month treatment. Arrows in D indicate clusters of cells containing K8 pS436. Filled arrowheads in G and H indicat...
PMC516018_F4_395.jpg
What is the core subject represented in this visual?
Distribution of keratin IFs and K8 pS436 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS436; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H); 5 month treatment. Arrows in D indicate clusters of cells containing K8 pS436. Filled arrowheads in G and H indicat...
PMC516018_F4_393.jpg
What does this image primarily show?
Distribution of keratin IFs and K8 pS436 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS436; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H); 5 month treatment. Arrows in D indicate clusters of cells containing K8 pS436. Filled arrowheads in G and H indicat...
PMC516018_F4_398.jpg
What is shown in this image?
Distribution of keratin IFs and K8 pS436 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS436; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H); 5 month treatment. Arrows in D indicate clusters of cells containing K8 pS436. Filled arrowheads in G and H indicat...
PMC516018_F4_399.jpg
What is the dominant medical problem in this image?
Distribution of keratin IFs and K8 pS436 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS436; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H); 5 month treatment. Arrows in D indicate clusters of cells containing K8 pS436. Filled arrowheads in G and H indicat...
PMC516018_F5_418.jpg
What is being portrayed in this visual content?
Distribution of keratin IFs and K18 pS33 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K18 pS33; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Asterisk in D shows an hepatocyte containing a high level of K18 pS33; arrow indicates a dilated ...
PMC516018_F5_420.jpg
What can you see in this picture?
Distribution of keratin IFs and K18 pS33 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K18 pS33; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Asterisk in D shows an hepatocyte containing a high level of K18 pS33; arrow indicates a dilated ...
PMC516018_F5_416.jpg
What does this image primarily show?
Distribution of keratin IFs and K18 pS33 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K18 pS33; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Asterisk in D shows an hepatocyte containing a high level of K18 pS33; arrow indicates a dilated ...
PMC516018_F5_422.jpg
Can you identify the primary element in this image?
Distribution of keratin IFs and K18 pS33 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K18 pS33; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Asterisk in D shows an hepatocyte containing a high level of K18 pS33; arrow indicates a dilated ...
PMC516018_F5_415.jpg
What is the main focus of this visual representation?
Distribution of keratin IFs and K18 pS33 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K18 pS33; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Asterisk in D shows an hepatocyte containing a high level of K18 pS33; arrow indicates a dilated ...
PMC516018_F5_421.jpg
What does this image primarily show?
Distribution of keratin IFs and K18 pS33 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K18 pS33; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Asterisk in D shows an hepatocyte containing a high level of K18 pS33; arrow indicates a dilated ...
PMC516018_F7_385.jpg
What is the focal point of this photograph?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS79; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79; asterisk shows a damaged hepatocyte. Fil...
PMC516018_F7_388.jpg
What does this image primarily show?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS79; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79; asterisk shows a damaged hepatocyte. Fil...
PMC516018_F7_391.jpg
What stands out most in this visual?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS79; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79; asterisk shows a damaged hepatocyte. Fil...
PMC516018_F7_390.jpg
What is the central feature of this picture?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS79; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79; asterisk shows a damaged hepatocyte. Fil...
PMC516018_F7_389.jpg
What can you see in this picture?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS79; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79; asterisk shows a damaged hepatocyte. Fil...
PMC516018_F7_386.jpg
Can you identify the primary element in this image?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS79; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79; asterisk shows a damaged hepatocyte. Fil...
PMC516018_F7_384.jpg
What is the dominant medical problem in this image?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS79; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79; asterisk shows a damaged hepatocyte. Fil...
PMC516018_F7_387.jpg
What can you see in this picture?
Distribution of keratin IFs and K8 pS79 in hepatocytes from control and GF-fed C3H mice. A, C, E, G keratin IFs; B, D, F, H K8 pS79; A, B) control; C, D) 2 week treatment; E, F) 6 week treatment; G, H) 5 month treatment. Arrow in D indicates clusters of cells containing K8 pS79; asterisk shows a damaged hepatocyte. Fil...