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PMC2491650_F1_26095.jpg | What can you see in this picture? | Imaging studies. (A) Initial magnetic resonance imaging revealed signs of cerebral atrophy with a prominent inter-hemispheral fissure at the age of 23 years. (B) The second magnetic resonance imaging 11 years later did not reveal any progression of cerebral atrophy nor any other signs of cystinosis-associated encephalo... |
PMC2491651_F1_26099.jpg | What key item or scene is captured in this photo? | Radiographic, pathological and microbiological findings. (A) Computed tomography (CT) showing the presence of an air bubble anterior to the vascular graft, suggesting an aorto-pulmonary fistula. (B) Surgically excised Dacron prosthesis from which Mycobacterium tuberculosis DNA was amplified and M. tuberculosis grew in ... |
PMC2491651_F1_26100.jpg | What is the dominant medical problem in this image? | Radiographic, pathological and microbiological findings. (A) Computed tomography (CT) showing the presence of an air bubble anterior to the vascular graft, suggesting an aorto-pulmonary fistula. (B) Surgically excised Dacron prosthesis from which Mycobacterium tuberculosis DNA was amplified and M. tuberculosis grew in ... |
PMC2491651_F1_26098.jpg | What is the central feature of this picture? | Radiographic, pathological and microbiological findings. (A) Computed tomography (CT) showing the presence of an air bubble anterior to the vascular graft, suggesting an aorto-pulmonary fistula. (B) Surgically excised Dacron prosthesis from which Mycobacterium tuberculosis DNA was amplified and M. tuberculosis grew in ... |
PMC2491652_F2_26088.jpg | What is the core subject represented in this visual? | A retrograde urethrogram showing a tight ring urethral stricture in the middle third of the penile urethra. |
PMC2491653_F1_26087.jpg | What is the principal component of this image? | Abdominal computed tomography on admission showing a mass in Couinaud segment 7 and segment 8 of the liver and intraperitoneal fluid. |
PMC2491653_F3_26086.jpg | What does this image primarily show? | Chest computed tomography showing lung metastasis with pleural seeding 80 months after hepatectomy. |
PMC2492866_F6_26105.jpg | What is the main focus of this visual representation? | Localization of GFP in transgenic tobacco as directed by the signal peptide of Vv-AMP1. Localization of GFP observed in the apoplasts of the following tissues, organs and cells in the leaf petiole: (A) cortex; (B) the guard cells of the stomata and (C) the trichoma. A1, B1 and C1 show light microscopic photos of these ... |
PMC2492866_F6_26106.jpg | What object or scene is depicted here? | Localization of GFP in transgenic tobacco as directed by the signal peptide of Vv-AMP1. Localization of GFP observed in the apoplasts of the following tissues, organs and cells in the leaf petiole: (A) cortex; (B) the guard cells of the stomata and (C) the trichoma. A1, B1 and C1 show light microscopic photos of these ... |
PMC2492866_F6_26107.jpg | What key item or scene is captured in this photo? | Localization of GFP in transgenic tobacco as directed by the signal peptide of Vv-AMP1. Localization of GFP observed in the apoplasts of the following tissues, organs and cells in the leaf petiole: (A) cortex; (B) the guard cells of the stomata and (C) the trichoma. A1, B1 and C1 show light microscopic photos of these ... |
PMC2492866_F6_26112.jpg | What is the principal component of this image? | Localization of GFP in transgenic tobacco as directed by the signal peptide of Vv-AMP1. Localization of GFP observed in the apoplasts of the following tissues, organs and cells in the leaf petiole: (A) cortex; (B) the guard cells of the stomata and (C) the trichoma. A1, B1 and C1 show light microscopic photos of these ... |
PMC2492867_F2_26118.jpg | What is the central feature of this picture? | TCL1 participates in the control of both leaf trichome and root hair formation. (A) TCL1 functions redundantly with other single-repeat R3 MYB transcription factors to control trichome formation on leaves. Pictures were taken from 2-week-old, soil-grown seedlings. (B) TCL1 functions redundantly with other single-repeat... |
PMC2492867_F2_26119.jpg | What object or scene is depicted here? | TCL1 participates in the control of both leaf trichome and root hair formation. (A) TCL1 functions redundantly with other single-repeat R3 MYB transcription factors to control trichome formation on leaves. Pictures were taken from 2-week-old, soil-grown seedlings. (B) TCL1 functions redundantly with other single-repeat... |
PMC2492867_F2_26114.jpg | What key item or scene is captured in this photo? | TCL1 participates in the control of both leaf trichome and root hair formation. (A) TCL1 functions redundantly with other single-repeat R3 MYB transcription factors to control trichome formation on leaves. Pictures were taken from 2-week-old, soil-grown seedlings. (B) TCL1 functions redundantly with other single-repeat... |
PMC2492867_F2_26113.jpg | What is being portrayed in this visual content? | TCL1 participates in the control of both leaf trichome and root hair formation. (A) TCL1 functions redundantly with other single-repeat R3 MYB transcription factors to control trichome formation on leaves. Pictures were taken from 2-week-old, soil-grown seedlings. (B) TCL1 functions redundantly with other single-repeat... |
PMC2492867_F2_26117.jpg | What is the focal point of this photograph? | TCL1 participates in the control of both leaf trichome and root hair formation. (A) TCL1 functions redundantly with other single-repeat R3 MYB transcription factors to control trichome formation on leaves. Pictures were taken from 2-week-old, soil-grown seedlings. (B) TCL1 functions redundantly with other single-repeat... |
PMC2492867_F2_26116.jpg | What is the dominant medical problem in this image? | TCL1 participates in the control of both leaf trichome and root hair formation. (A) TCL1 functions redundantly with other single-repeat R3 MYB transcription factors to control trichome formation on leaves. Pictures were taken from 2-week-old, soil-grown seedlings. (B) TCL1 functions redundantly with other single-repeat... |
PMC2492867_F2_26115.jpg | Describe the main subject of this image. | TCL1 participates in the control of both leaf trichome and root hair formation. (A) TCL1 functions redundantly with other single-repeat R3 MYB transcription factors to control trichome formation on leaves. Pictures were taken from 2-week-old, soil-grown seedlings. (B) TCL1 functions redundantly with other single-repeat... |
PMC2492868_F1_26133.jpg | What is the focal point of this photograph? | Upregulation of connexin-43 in tumor cell-endothelial cell contact areas in vitro and in vivo. (a)-(d) Immunocytofluorescence detecting connexin-43 (Cx43; red) in co-culture of 4T1-GFP cells (green cytoplasmic staining with blue nuclei) and pulmonary microvascular endothelial cells (PMVECs; blue nuclei without cytoplas... |
PMC2492868_F1_26134.jpg | What is the main focus of this visual representation? | Upregulation of connexin-43 in tumor cell-endothelial cell contact areas in vitro and in vivo. (a)-(d) Immunocytofluorescence detecting connexin-43 (Cx43; red) in co-culture of 4T1-GFP cells (green cytoplasmic staining with blue nuclei) and pulmonary microvascular endothelial cells (PMVECs; blue nuclei without cytoplas... |
PMC2492868_F1_26132.jpg | What is the dominant medical problem in this image? | Upregulation of connexin-43 in tumor cell-endothelial cell contact areas in vitro and in vivo. (a)-(d) Immunocytofluorescence detecting connexin-43 (Cx43; red) in co-culture of 4T1-GFP cells (green cytoplasmic staining with blue nuclei) and pulmonary microvascular endothelial cells (PMVECs; blue nuclei without cytoplas... |
PMC2492868_F2_26153.jpg | What stands out most in this visual? | Connexin-43 expression marks the sites of micrometastases. (a)-(d), (h) Immunohistofluorescence fixed sections of mouse lung after 12 hours of tail vein injection of 4T1-GFP cells or connexin-43 (Cx43) mutant variants C61S, G138R, or Cx43OE. Autofluorescence of lung tissue and 4T1-GFP fluorescence (green fluorescent pr... |
PMC2492868_F2_26151.jpg | What does this image primarily show? | Connexin-43 expression marks the sites of micrometastases. (a)-(d), (h) Immunohistofluorescence fixed sections of mouse lung after 12 hours of tail vein injection of 4T1-GFP cells or connexin-43 (Cx43) mutant variants C61S, G138R, or Cx43OE. Autofluorescence of lung tissue and 4T1-GFP fluorescence (green fluorescent pr... |
PMC2492868_F2_26149.jpg | What's the most prominent thing you notice in this picture? | Connexin-43 expression marks the sites of micrometastases. (a)-(d), (h) Immunohistofluorescence fixed sections of mouse lung after 12 hours of tail vein injection of 4T1-GFP cells or connexin-43 (Cx43) mutant variants C61S, G138R, or Cx43OE. Autofluorescence of lung tissue and 4T1-GFP fluorescence (green fluorescent pr... |
PMC2492868_F2_26147.jpg | What is the dominant medical problem in this image? | Connexin-43 expression marks the sites of micrometastases. (a)-(d), (h) Immunohistofluorescence fixed sections of mouse lung after 12 hours of tail vein injection of 4T1-GFP cells or connexin-43 (Cx43) mutant variants C61S, G138R, or Cx43OE. Autofluorescence of lung tissue and 4T1-GFP fluorescence (green fluorescent pr... |
PMC2492868_F2_26150.jpg | What is the main focus of this visual representation? | Connexin-43 expression marks the sites of micrometastases. (a)-(d), (h) Immunohistofluorescence fixed sections of mouse lung after 12 hours of tail vein injection of 4T1-GFP cells or connexin-43 (Cx43) mutant variants C61S, G138R, or Cx43OE. Autofluorescence of lung tissue and 4T1-GFP fluorescence (green fluorescent pr... |
PMC2492868_F2_26148.jpg | What is the focal point of this photograph? | Connexin-43 expression marks the sites of micrometastases. (a)-(d), (h) Immunohistofluorescence fixed sections of mouse lung after 12 hours of tail vein injection of 4T1-GFP cells or connexin-43 (Cx43) mutant variants C61S, G138R, or Cx43OE. Autofluorescence of lung tissue and 4T1-GFP fluorescence (green fluorescent pr... |
PMC2492868_F2_26146.jpg | Can you identify the primary element in this image? | Connexin-43 expression marks the sites of micrometastases. (a)-(d), (h) Immunohistofluorescence fixed sections of mouse lung after 12 hours of tail vein injection of 4T1-GFP cells or connexin-43 (Cx43) mutant variants C61S, G138R, or Cx43OE. Autofluorescence of lung tissue and 4T1-GFP fluorescence (green fluorescent pr... |
PMC2492868_F2_26152.jpg | What is the main focus of this visual representation? | Connexin-43 expression marks the sites of micrometastases. (a)-(d), (h) Immunohistofluorescence fixed sections of mouse lung after 12 hours of tail vein injection of 4T1-GFP cells or connexin-43 (Cx43) mutant variants C61S, G138R, or Cx43OE. Autofluorescence of lung tissue and 4T1-GFP fluorescence (green fluorescent pr... |
PMC2492868_F3_26145.jpg | What is the dominant medical problem in this image? | Intratumor vessels and metastatic foci demonstrate increased connexin-43. Immunohistofluorescence for connexin-43 (Cx43) of mouse lung sections 12 days after tail vein injection of 4T1-GFP control cells or of cells expressing Cx43 variants C61S, G138R, or Cx43OE. Lung tissue autofluorescence and tumor cell green fluore... |
PMC2492868_F3_26140.jpg | What stands out most in this visual? | Intratumor vessels and metastatic foci demonstrate increased connexin-43. Immunohistofluorescence for connexin-43 (Cx43) of mouse lung sections 12 days after tail vein injection of 4T1-GFP control cells or of cells expressing Cx43 variants C61S, G138R, or Cx43OE. Lung tissue autofluorescence and tumor cell green fluore... |
PMC2492868_F3_26143.jpg | What stands out most in this visual? | Intratumor vessels and metastatic foci demonstrate increased connexin-43. Immunohistofluorescence for connexin-43 (Cx43) of mouse lung sections 12 days after tail vein injection of 4T1-GFP control cells or of cells expressing Cx43 variants C61S, G138R, or Cx43OE. Lung tissue autofluorescence and tumor cell green fluore... |
PMC2492868_F3_26142.jpg | What is shown in this image? | Intratumor vessels and metastatic foci demonstrate increased connexin-43. Immunohistofluorescence for connexin-43 (Cx43) of mouse lung sections 12 days after tail vein injection of 4T1-GFP control cells or of cells expressing Cx43 variants C61S, G138R, or Cx43OE. Lung tissue autofluorescence and tumor cell green fluore... |
PMC2492868_F3_26138.jpg | What is the dominant medical problem in this image? | Intratumor vessels and metastatic foci demonstrate increased connexin-43. Immunohistofluorescence for connexin-43 (Cx43) of mouse lung sections 12 days after tail vein injection of 4T1-GFP control cells or of cells expressing Cx43 variants C61S, G138R, or Cx43OE. Lung tissue autofluorescence and tumor cell green fluore... |
PMC2492868_F3_26144.jpg | What does this image primarily show? | Intratumor vessels and metastatic foci demonstrate increased connexin-43. Immunohistofluorescence for connexin-43 (Cx43) of mouse lung sections 12 days after tail vein injection of 4T1-GFP control cells or of cells expressing Cx43 variants C61S, G138R, or Cx43OE. Lung tissue autofluorescence and tumor cell green fluore... |
PMC2492868_F4_26121.jpg | What is the core subject represented in this visual? | Tumor cells and endothelial cells share common borders in vitro. (a), (b) 4T1-GFP and pulmonary microvascular endothelial cells were plated together in co-culture and examined by DIC imaging. (c), (d) The same fields were imaged in the green fluorescent protein (GFP) channel to reveal the presence of the 4T1-GFP cells.... |
PMC2492868_F4_26120.jpg | What is the focal point of this photograph? | Tumor cells and endothelial cells share common borders in vitro. (a), (b) 4T1-GFP and pulmonary microvascular endothelial cells were plated together in co-culture and examined by DIC imaging. (c), (d) The same fields were imaged in the green fluorescent protein (GFP) channel to reveal the presence of the 4T1-GFP cells.... |
PMC2492868_F4_26125.jpg | What can you see in this picture? | Tumor cells and endothelial cells share common borders in vitro. (a), (b) 4T1-GFP and pulmonary microvascular endothelial cells were plated together in co-culture and examined by DIC imaging. (c), (d) The same fields were imaged in the green fluorescent protein (GFP) channel to reveal the presence of the 4T1-GFP cells.... |
PMC2492868_F4_26123.jpg | What does this image primarily show? | Tumor cells and endothelial cells share common borders in vitro. (a), (b) 4T1-GFP and pulmonary microvascular endothelial cells were plated together in co-culture and examined by DIC imaging. (c), (d) The same fields were imaged in the green fluorescent protein (GFP) channel to reveal the presence of the 4T1-GFP cells.... |
PMC2492868_F4_26122.jpg | Can you identify the primary element in this image? | Tumor cells and endothelial cells share common borders in vitro. (a), (b) 4T1-GFP and pulmonary microvascular endothelial cells were plated together in co-culture and examined by DIC imaging. (c), (d) The same fields were imaged in the green fluorescent protein (GFP) channel to reveal the presence of the 4T1-GFP cells.... |
PMC2492868_F4_26124.jpg | What can you see in this picture? | Tumor cells and endothelial cells share common borders in vitro. (a), (b) 4T1-GFP and pulmonary microvascular endothelial cells were plated together in co-culture and examined by DIC imaging. (c), (d) The same fields were imaged in the green fluorescent protein (GFP) channel to reveal the presence of the 4T1-GFP cells.... |
PMC2492868_F6_26126.jpg | What can you see in this picture? | Expression of connexin-43 by the mutant variants. (A) Immunocytofluorescence analysis of connexin-43 (Cx43) expression in wild-type 4T1-GFP tumor cells and in 4T1-GFP cells transfected with expression vectors of the mutant G138R and C61S in addition to a vector expressing two copies of wild-type Cx43 (Cx43OE). Endogeno... |
PMC2492868_F6_26127.jpg | What is the dominant medical problem in this image? | Expression of connexin-43 by the mutant variants. (A) Immunocytofluorescence analysis of connexin-43 (Cx43) expression in wild-type 4T1-GFP tumor cells and in 4T1-GFP cells transfected with expression vectors of the mutant G138R and C61S in addition to a vector expressing two copies of wild-type Cx43 (Cx43OE). Endogeno... |
PMC2492868_F6_26131.jpg | What can you see in this picture? | Expression of connexin-43 by the mutant variants. (A) Immunocytofluorescence analysis of connexin-43 (Cx43) expression in wild-type 4T1-GFP tumor cells and in 4T1-GFP cells transfected with expression vectors of the mutant G138R and C61S in addition to a vector expressing two copies of wild-type Cx43 (Cx43OE). Endogeno... |
PMC2492868_F6_26128.jpg | What is shown in this image? | Expression of connexin-43 by the mutant variants. (A) Immunocytofluorescence analysis of connexin-43 (Cx43) expression in wild-type 4T1-GFP tumor cells and in 4T1-GFP cells transfected with expression vectors of the mutant G138R and C61S in addition to a vector expressing two copies of wild-type Cx43 (Cx43OE). Endogeno... |
PMC2493026_f5_26155.jpg | What can you see in this picture? | Electron micrographs obtained after transduction with HC Ad.VEGF-A. A: An invagination of the the endothelium into the lumen of the choriocapillaris containing extracellular matrix (asterisk) is shown. This caused the patchy appearance of the choriocapillaris lumen presented in Figure 4. B: A cell (asterisk) was locate... |
PMC2493026_f5_26157.jpg | What object or scene is depicted here? | Electron micrographs obtained after transduction with HC Ad.VEGF-A. A: An invagination of the the endothelium into the lumen of the choriocapillaris containing extracellular matrix (asterisk) is shown. This caused the patchy appearance of the choriocapillaris lumen presented in Figure 4. B: A cell (asterisk) was locate... |
PMC2493026_f5_26154.jpg | What stands out most in this visual? | Electron micrographs obtained after transduction with HC Ad.VEGF-A. A: An invagination of the the endothelium into the lumen of the choriocapillaris containing extracellular matrix (asterisk) is shown. This caused the patchy appearance of the choriocapillaris lumen presented in Figure 4. B: A cell (asterisk) was locate... |
PMC2493026_f5_26156.jpg | What's the most prominent thing you notice in this picture? | Electron micrographs obtained after transduction with HC Ad.VEGF-A. A: An invagination of the the endothelium into the lumen of the choriocapillaris containing extracellular matrix (asterisk) is shown. This caused the patchy appearance of the choriocapillaris lumen presented in Figure 4. B: A cell (asterisk) was locate... |
PMC2493026_f8_26160.jpg | What's the most prominent thing you notice in this picture? | Electron micrographs obtained after transduction with HC Ad.VEGF-A. A: Nuclei of the choriocapillaris appeared extremely frayed or fragmented (asterisks). Remnants of the elastic layer of Bruch’s membrane can be recognized (arrows). B: Trombocytes (T) aggregated in the choriocapillaris. Cells (black asterisk) migrated ... |
PMC2493026_f8_26158.jpg | Can you identify the primary element in this image? | Electron micrographs obtained after transduction with HC Ad.VEGF-A. A: Nuclei of the choriocapillaris appeared extremely frayed or fragmented (asterisks). Remnants of the elastic layer of Bruch’s membrane can be recognized (arrows). B: Trombocytes (T) aggregated in the choriocapillaris. Cells (black asterisk) migrated ... |
PMC2493026_f8_26161.jpg | What key item or scene is captured in this photo? | Electron micrographs obtained after transduction with HC Ad.VEGF-A. A: Nuclei of the choriocapillaris appeared extremely frayed or fragmented (asterisks). Remnants of the elastic layer of Bruch’s membrane can be recognized (arrows). B: Trombocytes (T) aggregated in the choriocapillaris. Cells (black asterisk) migrated ... |
PMC2493026_f8_26159.jpg | What key item or scene is captured in this photo? | Electron micrographs obtained after transduction with HC Ad.VEGF-A. A: Nuclei of the choriocapillaris appeared extremely frayed or fragmented (asterisks). Remnants of the elastic layer of Bruch’s membrane can be recognized (arrows). B: Trombocytes (T) aggregated in the choriocapillaris. Cells (black asterisk) migrated ... |
PMC2493026_f8_26162.jpg | What is the dominant medical problem in this image? | Electron micrographs obtained after transduction with HC Ad.VEGF-A. A: Nuclei of the choriocapillaris appeared extremely frayed or fragmented (asterisks). Remnants of the elastic layer of Bruch’s membrane can be recognized (arrows). B: Trombocytes (T) aggregated in the choriocapillaris. Cells (black asterisk) migrated ... |
PMC2493034_pone-0002959-g002_26173.jpg | What is the core subject represented in this visual? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493034_pone-0002959-g002_26166.jpg | What is the focal point of this photograph? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493034_pone-0002959-g002_26167.jpg | What is the central feature of this picture? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493034_pone-0002959-g002_26175.jpg | What's the most prominent thing you notice in this picture? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493034_pone-0002959-g002_26172.jpg | What is the principal component of this image? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493034_pone-0002959-g002_26171.jpg | What is shown in this image? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493034_pone-0002959-g002_26170.jpg | What object or scene is depicted here? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493034_pone-0002959-g002_26169.jpg | What key item or scene is captured in this photo? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493034_pone-0002959-g002_26168.jpg | What is the core subject represented in this visual? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493034_pone-0002959-g002_26165.jpg | What is the dominant medical problem in this image? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493034_pone-0002959-g002_26174.jpg | What can you see in this picture? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493034_pone-0002959-g002_26176.jpg | What's the most prominent thing you notice in this picture? | Mmp13 mRNA is expressed by a subset of α-smooth muscle actin positive carcinoma-associated fibroblasts.MMTV-PyMT tumors from 13-week-old mice were processed for in situ hybridization for Mmp13 (a–e, i–l), Mmp2 (g), and Mmp14 (h). For clarity the hybridization signals (silver grains) are shown with dark-field illuminati... |
PMC2493035_pone-0002937-g001_26163.jpg | What is the central feature of this picture? | Tubulo-interstitial CD68+ cell infiltrate in DN.(a) In DN a prominent infiltration of CD68+ cells (monocytes/macrophages, stained in red) is observed in the tubulo-interstitium. A glomerulus showing nodular glomerulosclerosis (Kimmelstiel-Wilson), a classical histological sign for DN, has no prominent infiltrate. In co... |
PMC2494540_F1_26178.jpg | What is the central feature of this picture? | MRI showing complete occlusion of proximal 4 cm of left subclavian artery with retrograde filling via the left vertebral. |
PMC2494540_F1_26177.jpg | Can you identify the primary element in this image? | MRI showing complete occlusion of proximal 4 cm of left subclavian artery with retrograde filling via the left vertebral. |
PMC2494540_F2_26180.jpg | What stands out most in this visual? | Angiography of the great vessels. 2a: showing a 4 cm occlusion of the of left subclavian artery (red circle) with 2b: demonstrating retrograde filling of the subclavian via the left vertebral (blue circle). |
PMC2494540_F2_26179.jpg | What is the principal component of this image? | Angiography of the great vessels. 2a: showing a 4 cm occlusion of the of left subclavian artery (red circle) with 2b: demonstrating retrograde filling of the subclavian via the left vertebral (blue circle). |
PMC2494540_F3_26183.jpg | Describe the main subject of this image. | 3x, 3y: AP arteriography demonstrating retrograde filling of coeliac axis (green arrow) via a hypertrophied pancreatico-duodenal arcade (blue arrows) from the SMA (red arrow). Additional mild right renal artery stenosis also noted (asterix). 3z: Lateral abdominal aortography demonstrating the tight stenosis of the coel... |
PMC2494540_F3_26182.jpg | What is the central feature of this picture? | 3x, 3y: AP arteriography demonstrating retrograde filling of coeliac axis (green arrow) via a hypertrophied pancreatico-duodenal arcade (blue arrows) from the SMA (red arrow). Additional mild right renal artery stenosis also noted (asterix). 3z: Lateral abdominal aortography demonstrating the tight stenosis of the coel... |
PMC2494540_F3_26184.jpg | What is being portrayed in this visual content? | 3x, 3y: AP arteriography demonstrating retrograde filling of coeliac axis (green arrow) via a hypertrophied pancreatico-duodenal arcade (blue arrows) from the SMA (red arrow). Additional mild right renal artery stenosis also noted (asterix). 3z: Lateral abdominal aortography demonstrating the tight stenosis of the coel... |
PMC2494542_F1_26181.jpg | What is the main focus of this visual representation? | Photograph showing a subcutaneous neck drain in the left neck wound. |
PMC2494542_F2_26185.jpg | What's the most prominent thing you notice in this picture? | Series of chest radiographs. a) Chest radiograph in recovery showing bilateral pneumothoraces despite transhiatal chest drains. Note corrugated drain in left side of neck. b) Chest radiograph taken on day 1 revealing collapse of left lung despite chest drainage. Note resolution of right pneumothorax. c) Chest radiograp... |
PMC2494542_F2_26186.jpg | What is the central feature of this picture? | Series of chest radiographs. a) Chest radiograph in recovery showing bilateral pneumothoraces despite transhiatal chest drains. Note corrugated drain in left side of neck. b) Chest radiograph taken on day 1 revealing collapse of left lung despite chest drainage. Note resolution of right pneumothorax. c) Chest radiograp... |
PMC2494559_pbio-0060195-g001_26190.jpg | What is the dominant medical problem in this image? | Amyloid-Like Character of Three Bacterial Inclusion BodiesCR birefringence and Thio T binding of inclusion bodies are indicative of amyloid formation. Under cross-polarized light with 10× magnification, CR birefringence is observed for BMP2(13–74), ESAT-6, and MOG(ECD). Larger images together with the corresponding pic... |
PMC2494559_pbio-0060195-g001_26189.jpg | What is the core subject represented in this visual? | Amyloid-Like Character of Three Bacterial Inclusion BodiesCR birefringence and Thio T binding of inclusion bodies are indicative of amyloid formation. Under cross-polarized light with 10× magnification, CR birefringence is observed for BMP2(13–74), ESAT-6, and MOG(ECD). Larger images together with the corresponding pic... |
PMC2494576_fig4_26193.jpg | Can you identify the primary element in this image? | Functional connectivity analysis of regular inflection. Connectivity analysis in a group of healthy volunteers (20–40 years; based on data reported in Stamatakis et al. 2005). (a) The three-way interaction showing that the LACC predicts greater fronto-temporal interaction (LIFG and LMTG) in the context of regularly inf... |
PMC2494576_fig4_26192.jpg | What stands out most in this visual? | Functional connectivity analysis of regular inflection. Connectivity analysis in a group of healthy volunteers (20–40 years; based on data reported in Stamatakis et al. 2005). (a) The three-way interaction showing that the LACC predicts greater fronto-temporal interaction (LIFG and LMTG) in the context of regularly inf... |
PMC2494576_fig7_26195.jpg | What is the dominant medical problem in this image? | Functional connectivity analysis of syntactic and semantic ambiguity effects. Connectivity analysis using a predictor time series (marked by asterisks) found to be a statistical peak in the group (young normal) analysis. (a) The contrast of semantically ambiguous–unambiguous activity in the LIFG positively predicts act... |
PMC2494576_fig7_26196.jpg | What is the main focus of this visual representation? | Functional connectivity analysis of syntactic and semantic ambiguity effects. Connectivity analysis using a predictor time series (marked by asterisks) found to be a statistical peak in the group (young normal) analysis. (a) The contrast of semantically ambiguous–unambiguous activity in the LIFG positively predicts act... |
PMC2494576_fig11_26198.jpg | What key item or scene is captured in this photo? | Semantic and syntactic connectivity effects for patient P2. (a) T1-weighted MR image for patient P2 (with lesion in L posterior MTG, indicated by a white arrow). (b) Connectivity analysis for semantically ambiguous words using predictors (see asterisk) derived from P2's activation peaks, overlaid on his three-dimension... |
PMC2494576_fig11_26200.jpg | What stands out most in this visual? | Semantic and syntactic connectivity effects for patient P2. (a) T1-weighted MR image for patient P2 (with lesion in L posterior MTG, indicated by a white arrow). (b) Connectivity analysis for semantically ambiguous words using predictors (see asterisk) derived from P2's activation peaks, overlaid on his three-dimension... |
PMC2494576_fig11_26202.jpg | What is the central feature of this picture? | Semantic and syntactic connectivity effects for patient P2. (a) T1-weighted MR image for patient P2 (with lesion in L posterior MTG, indicated by a white arrow). (b) Connectivity analysis for semantically ambiguous words using predictors (see asterisk) derived from P2's activation peaks, overlaid on his three-dimension... |
PMC2494588_fig3_26203.jpg | What can you see in this picture? | (a) A coronar magnetic resonance imaging (T2-weighted) showing the tumor infiltration of the knee. (b) An axial T2-weighted sequence showing the tumor extension of the whole quadriceps muscles. |
PMC2494588_fig5_26205.jpg | What's the most prominent thing you notice in this picture? | (a) An anterior-posterior
radiograph showing the ankle without relevant signs of arthrosis 1 years
postoperatively. Osteopenia due to the limited exposure of the leg. (b) An anterior-posterior and lateral
radiograph showing the ankle 15 years postoperatively without relevant signs of
arthrosis. |
PMC2494609_pgen-1000158-g007_26207.jpg | What can you see in this picture? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
PMC2494609_pgen-1000158-g007_26210.jpg | What is being portrayed in this visual content? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
PMC2494609_pgen-1000158-g007_26217.jpg | What stands out most in this visual? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
PMC2494609_pgen-1000158-g007_26219.jpg | What stands out most in this visual? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
PMC2494609_pgen-1000158-g007_26221.jpg | What key item or scene is captured in this photo? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
PMC2494609_pgen-1000158-g007_26214.jpg | What key item or scene is captured in this photo? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
PMC2494609_pgen-1000158-g007_26211.jpg | What's the most prominent thing you notice in this picture? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
PMC2494609_pgen-1000158-g007_26213.jpg | What stands out most in this visual? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
PMC2494609_pgen-1000158-g007_26212.jpg | What stands out most in this visual? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
PMC2494609_pgen-1000158-g007_26222.jpg | What is the dominant medical problem in this image? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
PMC2494609_pgen-1000158-g007_26223.jpg | What is shown in this image? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
PMC2494609_pgen-1000158-g007_26215.jpg | Can you identify the primary element in this image? | Subcellular Localization of Mutant Forms of PBG.Confocal microscopic observation of GFP fluorescence in transgenic Arabidopsis seedlings. Hypocotyl epidermal cells of 3-day-old seedlings were observed. Dark-grown seedlings (upper), those treated with cW for 2 min (middle) and those treated with cR for 24 hr (lower) are... |
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