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ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0kvxv8908g074y6744eg66.jpg
Where in the image is the anatomical landmark?
Center, Center-left
splits/sfolder_3/PMC2234406_F2_17408.jpg
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Scanned images of DAB-stained, spotted immobilised rHRP activity. WT, Wildtype; Mutant 1, R118K/R159K/R283K; Mutant 2, R118K/R159K; Mutant 3, R118K/R159K/K232N/K241F/R283K; Mutant 4, R118K/R159K/K232N/K241F. Time points indicated on the left are in hours. DAB coloration indicates peroxidase activity; this was noted wit...
splits/subfolder_3/PMC2584338_F2_30260.jpg
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Expression of cell surface markers of tumor spheres before and after differentiation (×400). A-C, tumor spheres before differentiation. D-I, one week after FBS-induced differentiation. A, D, G, immunofluorescence staining for nestin (green). B, immunofluorescence staining for CD133 (red). E, immunofluorescence staining...
data_PathVQA/pathvqa_maml/t0/train/inside_endocrine/train_1447.jpg
Where does this belong to?
endocrine system
data_PathVQA/pathvqa_maml/val/cell_other/train_2779.jpg
Does this image show scleroderma?
yes
roco-dataset/data/train/radiology/images/ROCO_12827.jpg
Write a terse but informative summary of the picture.
Arteriovenous fistula. Color Doppler ultrasound shows an abnormal focus of increased turbulent flow in the midpole.
splits/subfolder_2/PMC3443877_F1_155324.jpg
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Ablation of RIPV: different positions of HIFU balloon catheter relative to esophageal temperature probe. A. HIFU balloon catheter far away from ET probe (LAO projection); B. Direction of HIFU beam pointed away from ET probe (RAO projection); C. HIFU balloon catheter close to ET probe (LAO projection); D. Direction of ...
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0lbwzfdp4g086uc9o53o63.jpg
What type of procedure is the image taken from?
Colonoscopy
data_PathVQA/pathvqa_maml/t0/train_unlabel/train_0832.jpg
What is one of the classic features of this disorder?
a wide-eyed
roco-dataset/data/train/radiology/images/ROCO_81438.jpg
Relay a brief, clear account of the picture shown.
Chest X-ray 5 months post endoscopic treatment of pancreatico-pleural fistula.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0kvxv69064074ydvrycsa1.jpg
Is this finding easy to detect?
No
splits/subfolder_2/PMC4584271_pathogens-04-00529-f001_427253.jpg
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Histopathology of the central nervous system (CNS) and heart. Mononuclear leukocytic infiltrate (black arrow) in the neuropil of brains from NZWRs infected with WNVNSW2011 (A), MVE1-51 (B) and CTRs- infected with WNVTX8667 (C) on day 7 pi. Mononuclear leukocytic infiltrate in myocardium of a NZWR infected with WNVNSW20...
roco-dataset/data/train/radiology/images/ROCO_79501.jpg
Offer a succinct explanation of the picture presented.
Case 2 preoperative orthopantomogram
splits/sfolder_3/PMC3765403_pone-0075204-g003_230000.jpg
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Time lapse imaging of Dmp1Cre/Ai9 derived bone chips.Bone chips were imaged every 40 minutes starting at day three of culture. The movement of Dmp1Cre+/Ai9 cells within the bone chips and their expulsion onto the culture plate was observed (moving cell is indicated by the arrow). Representative images spanning a 14 h 2...
splits/sfolder_3/PMC3210724_fig7_114666.jpg
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Edge spread function of channel 645 acquired at 15 keV with the threshold set at half of the X-ray energy and standard settings in SPC and ToT mode. The estimated values for the ESF obtained by fitting the experimental points in SPC and ToT mode with a trapezoidal function are reported in the legend. is the FWHM of th...
splits/subfolder_3/PMC3591374_pone-0058726-g001_190575.jpg
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2D and 3D images of microcomputed tomography.(A) Scout view of the Postn−/− mice showing alteration of the enamel (*) that affects the incisor from the apex to the incisor edge. (B) 3D reconstruction of our region of interest for the alveolar and basal bone compartment. (C) Sagittal slice (D) coronal slice (E) Axial sl...
data_PathVQA/pathvqa_maml/t0/train_unlabel/train_1672.jpg
Does this image show stomach primary?
yes
data_PathVQA/pathvqa_maml/t0/train_unlabel/train_2373.jpg
What does this image show?
brain
splits/subfolder_3/PMC3629075_fig-4_199286.jpg
Offer a thorough analysis of the image
Sub-cellular localization of GFP tagged 40S RPs in salivary glands.Leftmost panels show micrographs of salivary gland cells expressing the respective GFP tagged 40S RPs. Middle panels show DAPI staining of the nucleus. Right panels show merged images of the GFP and DAPI signal. The images are confocal microscopy sectio...
roco-dataset/data/train/radiology/images/ROCO_55565.jpg
Give a short and clear explanation of the subsequent image.
Fluoroscopic view showing the grasper being advanced in the direction of the visualized misplaced broken guidewire and the jaws were opened after directing them towards the broken guidewire
roco-dataset/data/train/radiology/images/ROCO_11275.jpg
Describe the image concisely.
Pre-operative MRI.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/cl8k2u1q41egz08329yg05iml.jpg
Are there any instruments in the image?
No
splits/subfolder_4/PMC3677323_F8_210089.jpg
Characterize the image using a well-detailed description
SEM images of male soft parts of Polycopetta quadrispinata sp. n. A left lateral view of whole body with left valve removed B left lateral view of frontal organ C right lateral view of distal area of antennula D left lateral view of antennal endopodite. Arrow indicates a seta with serrations at ventrodistal end. Arrowh...
splits/sfolder_1/PMC2722669_F8_43072.jpg
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Contrasting regulation of tight junctions among VHL mutants of different disease types in RCC10. RCC10 cells lines (as indicated; all created by retroviral infection) were grown to confluence on coverslips and immunostaining for ZO-1 (left panels) was performed (original magnification of 1000×). DAPI labeled nuclei of ...
roco-dataset/data/train/radiology/images/ROCO_12701.jpg
Offer a succinct explanation of the picture presented.
A CTA showed mesenteric artery thrombosis and abdominal aorta calcification in 2008.
splits/subfolder_3/PMC4043200_F2_293757.jpg
Offer a thorough analysis of the image
Correlation of late gadolinium enhancement and T2-weighted (T2) imaging findings and histopathology in a 52 yo male undergoing cardiac transplantation. Region of increased T2 signal [A] demonstrates large vascular channels embedded within dense fibrosis (arrows), staining positive for lymphatic endothelium (right panel...
roco-dataset/data/train/radiology/images/ROCO_74345.jpg
Create a compact narrative representing the image presented
MRV of the brain; the left transverse sinus thrombosis
data_PathVQA/pathvqa_maml/test/cell_sparse/train_0076.jpg
Is moebic liver abscess composed of dense fibrous tissue which shows nonspecific inflammation?
no
splits/subfolder_2/PMC4356288_f3-ol-09-04-1795_366310.jpg
Explain the various aspects of the image before you
Primary central nervous system lymphoma in the splenium of the corpus callosum (case 9). Preoperative imaging demonstrated that the lesion displayed a high density on (A) computed tomography (CT) scans and an equal-T1 and long-T2 signal on (B-G) magnetic resonance imaging (MRI) scans. The signals were significantly enh...
roco-dataset/data/train/radiology/images/ROCO_00475.jpg
Present a compact description of the photo’s key features.
Ultrasound demonstrates an anechoic area in the right lower quadrant indicating a large amount of free fluid
splits/subfolder_4/PMC4290091_Fig3_349917.jpg
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A: X-ray images, radiolucent MWCNT (triangle) and Ag/AgCl (arrow) electrodes. B: CT scan image revealing radiating artifacts from silver electrodes (arrow). C: No artifact from MWCNT electrode (triangle). D: Ag/AgCl electrode (arrow) producing linear susceptibility artifact (black triangle) in subcutaneous tissue in ...
roco-dataset/data/train/radiology/images/ROCO_02846.jpg
Present a compact description of the photo’s key features.
right hepatic artery after embolization.
data_PathVQA/pathvqa_maml/t0/train/cell_dense/train_2958.jpg
Does conjoined twins show coronary artery atherosclerosis?
no
roco-dataset/data/train/radiology/images/ROCO_66162.jpg
Present a compact description of the photo’s key features.
IOPA radiograph (post-op) at 3 month follow-up
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/clb0kvxvq913o074y7lnz0fhw.jpg
How many findings are present?
2
ImageClef-2019-VQA-Med-Training/Train_images/synpic46957.jpg
what is the primary abnormality in this image?
autosomal recessive polycystic kidney disease
splits/subfolder_2/PMC3734281_pone-0070595-g007_222911.jpg
Illustrate the image through a descriptive explanation
Localization of fibronectin in invadosomal degradation zones.HTM cells were pretreated with TGF-β for 3d, plated in the gelatine degradation assay and stained for fibronectin after 24 h. Confocal micrographs depict localization of gelatine and fibronectin. Close-up views of distinct areas (A, B, C) depict reticular fib...
splits/subfolder_3/PMC3530753_fig1_175170.jpg
Write a terse but informative summary of the picture.
Preoperative radiograph.
splits/subfolder_4/PMC4550893_f2_417936.jpg
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Uncommon carcinoma types in the proximal stomach exhibiting a protruded endoscopic pattern at the gastroesophageal junction (A) with a papillary histology type (B), or an excavated endoscopic appearance (C, arrow) and histology of carcinoma with lymphoid stroma (D), confirmed with positive in situ hybridization for the...
splits/subfolder_3/PMC3552840_F2_180764.jpg
Provide a brief description of the given image.
Topography (a) and current map (b) with +2 mV sample bias. The regions I, II, and III are discussed in the main text.
splits/subfolder_2/PMC4364945_fig02_369077.jpg
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Phb2pko mice develop glomerulosclerosis A PAS staining of kidney sections (scale bar: 20 μm).B Immunohistochemistry for podocin on kidney sections (scale bar: 20 μm).C Analysis of podocyte foot processes in electron micrographs (scale bar: 0.7 μm). FP, podocyte foot processes; GBM, glomerular basement membrane; EC, en...
splits/subfolder_2/PMC3863512_fig3_251988.jpg
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(a) Hematoxylin-eosin stain of melanoma in terminal ileum. (b) Hematoxylin-eosin stain of melanoma in terminal ileum, original magnification ×400. (c) Specimen stained with c-kit immunohistochemistry, original magnification ×400. (d) Specimen stained with HMB 45+ antibody original magnification ×400.
splits/sfolder_2/PMC4540988_fig2_415577.jpg
Write a terse but informative summary of the picture.
Patient's CT angiography of the abdomen revealed splenomegaly.
ImageCLEFmed-MEDVQA-GI-2023-Development-Dataset/images/cla820glqs4tn071u2kk21l0i.jpg
Where in the image is the abnormality?
Center, Upper-left, Upper-right, Lower-left, Lower-right, Center-left, Center-right, Upper-center, Lower-center
ImageClef-2019-VQA-Med-Training/Train_images/synpic36991.jpg
what is abnormal in the ct scan?
hemiazygous and azygous continuation of the inferior vena cava
splits/subfolder_2/PMC4454732_fig2_393134.jpg
Offer a succinct explanation of the picture presented.
(a) Sigmoid colon biopsy showing lymphohistiocytic infiltration of lamina propria (hematoxylin and eosin stain, original magnification ×200). (b) Higher power view of sigmoid colon biopsy showing Michaelis-Gutmann bodies (arrows) (hematoxylin and eosin, original magnification ×400).
splits/sfolder_2/PMC3046445_F1_88622.jpg
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Representative immunohistochemical statinings of ER, PR, HER2, HER4, and cystatin M in DCIS and IBC lesions. The positive (upper row) and negative (lower row) immunostainings for cystatin M, ER, PR, HER2, and HER4 are shown in DCISs and IBCs. Most cells in the upper row of DCIS and IBC lesions show strong nuclear react...
splits/subfolder_3/PMC2291032_F2_19972.jpg
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Lymph node biopsy. Follicular destruction was demonstrated with immunohistochemistry, which revealed small clusters of CD10 positive small lymphocytes, corresponding to the residual germinal centers (Upper right panel, original magnification ×400). CD23 immunohistochemistry showed the dendritic cell network to be essen...
splits/subfolder_3/PMC4072085_F4_301522.jpg
Present a compact description of the photo’s key features.
DTZ staining of RAT-BM-MSCs. A. Spontaneously differentiated rat bone marrow mesenchymal stem cells (RAT-BM-MSCs) in DMEM stained positive for dithizone (DTZ). B. DTZ-positive cells in insulin-producing cell (IPC) differentiation media without exendin-4 (EX-4). C. DTZpositive RAT-BM-MSCs) in IPC differentiation me...
splits/sfolder_1/PMC4126687_pone-0103571-g001_312508.jpg
Give a short and clear explanation of the subsequent image.
The YWHAE (rs28365859) genotype-by-diagnosis interaction on gray matter volume.The regions showing interaction in all subjects are displayed by a hot colormap. The color bar shows t values corresponding to the color in the figure.
splits/subfolder_2/PMC2954547_f6-ijerph-07-03313_75869.jpg
Provide a detailed description of the given image
WA #1 WHA penetrator event aerosol particulates scraped from a single filter collector onto a grid sandwich and observed in the TEM. (a) Bright-field image of particulate aggregates. (b) Selected-area electron diffraction (SAED) pattern for aggregates in (a). Magnified bright-field image of (a). (d) Dark-field image of...
splits/subfolder_5/PMC3259112_F4_122176.jpg
Offer a succinct explanation of the picture presented.
Torsion of the gallbladder. Peroperative endoscopic image showing a gangrenous gallbladder, rotated around the cystic duct and artery.
splits/subfolder_3/PMC3570081_f1-etm-05-02-0499_184956.jpg
Describe the image concisely.
Surgical approach and endoscopic technique. (A) A nasobiliary duct installation in the biliary-jejunal loop as a marker. (B) Cholangiography. (C) Basket extraction of a stone. (D) Metal biliary stent installation in the biliary tract.
roco-dataset/data/train/radiology/images/ROCO_61860.jpg
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Coronal section of positron emission topography–computed tomography, demonstrating diffusely increased metabolic activity in the left thyroid, skull, liver, and soft tissue. Arrows highlight regions of increased metabolic activity.
splits/subfolder_3/PMC4337651_fig6s1_361322.jpg
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GFP fluorescence of additional colonies derived from single diploid cells hemizygous for individual SIR genes.All strains contained one copy of HMLα::cre and one copy of the RFP-GFP cassette. Scale bar, 2 mm.DOI: http://dx.doi.org/10.7554/eLife.05007.017
roco-dataset/data/train/radiology/images/ROCO_45190.jpg
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Digital OPG showing right mandibular third molar in stage G
splits/subfolder_5/PMC3366949_pone-0038284-g001_140406.jpg
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Immunostaining on murine APP/PS1 sections using ni3A and pa2H.The upper panels (A–D) show 10× magnifications of the resulting staining with cryosections of aged APP/PS1 mouse brain tissue including negative controls, while the lower panels (E–H) show similar staining performed with wildtype littermates.
splits/sfolder_2/PMC3788759_pone-0075232-g003_235218.jpg
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Deacylation kinetic and membrane association of GAP-43 at different doses of 2-BP.CHO-K1 cells coexpressing diacylated GAP-43-YFP and GalNAc-T-CFP were treated with 25, 50 or 150 µM 2-BP or vehicle (DMSO, Control), and the GAP-43 subcellular distribution was analyzed by live cell confocal microscopy at the indicated ti...
splits/subfolder_3/PMC3231396_f4-sensors-11-05112_118354.jpg
What is shown in this image?
Two typical x-ray images from an a-Se FPXI. Left, a typical x-ray image of a breast. Right, an x-ray image of a hand.
ImageClef-2019-VQA-Med-Training/Train_images/synpic23548.jpg
in what plane is this mri captured?
axial
splits/subfolder_4/PMC4025537_F2_289741.jpg
Provide a brief description of the given image.
Immunohistochemical validation of the tumor‒regressed lymph node. (A‒C) Cytokeratin AE1/AE3 immunostaining. (D-F) Ki- 67 staining. There were no Ki-67(+) proliferating cells around the tumor-regressed remnant keratin debris (Inserts showed higher magnification views).
splits/sfolder_3/PMC4247927_fig1_340322.jpg
What is shown in this image?
CT scan of the thorax showing a endoluminal polypoidal growth (arrow) arising from the posterior wall of the tracheal bifurcation.
splits/subfolder_5/PMC3678813_f5-rmmj-3-2-e0012_210424.jpg
Present a compact description of the photo’s key features.
Craniosynostosis of a 1-year-old female virtual patient created by the PSAR, to develop and simulate treatment protocols.
splits/subfolder_3/PMC3387240_pone-0039846-g004_143550.jpg
Explain the various aspects of the image before you
Examination of full-length GFP-tagged RC/BTB2 localization dynamically in transfected CHO cells.CHO cells were transfected by full-length RC/BTB2/pEGFP-C1 plasmid, living cell images were taken. Upper panel shows the images 16 hr after transfection, lower panel shows the images 21 hr after transfection. Notice that mul...
roco-dataset/data/train/radiology/images/ROCO_45367.jpg
Render a clear and concise summary of the photo.
Intraoperative positioning of implant before cementation
data_PathVQA/pathvqa_maml/val/illus_other/train_2217.jpg
Is metastatic carcinoma lung present?
no
splits/sfolder_2/PMC3307482_F1_130722.jpg
Render a clear and concise summary of the photo.
Histology of the lymph node biopsy. A. diffuse infiltrates of medium-sized lymphoid cells, which had fine chromatin and small nucleoli. B. tumor cells positive for CD3(Polyclonal). C.a part of tumor cells positive for TdT. D. tumor cells were negative for myeloperoxidase(Polyclonal).
splits/subfolder_4/PMC3850642_F1_248504.jpg
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Live primary human monocytes stimulated with CSN1S1. Primary human monocytes were incubated with CSN1S1 for 24 h with increasing CSN1S1 concentrations in comparison to medium control and 200 ng/ml LPS. Living cells were photographed at 400× magnification. Cells developed irregular cytoplasm (arrow) and pseudopodia (arr...
splits/subfolder_5/PMC4307188_Fig2_353056.jpg
What is shown in this image?
Ultrasonography findings with placental abruption. (A) Retroplacental hematoma. (B) Placenta.
ImageClef-2019-VQA-Med-Training/Train_images/synpic39942.jpg
what organ is this image of?
spine and contents
splits/subfolder_3/PMC4430312_fig2_386052.jpg
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Podoplanin defines adhesion rings at invadopodia of SCC cells. Confocal images showing specific localisation of podoplanin fused to GFP (PDPN-GFP) at invadopodia in HN5 cells cultured on glass coverslips covered with crosslinked gelatin (a, b) or TRITC-gelatin (c). Note that podoplanin is not present in all invadopodia...
splits/subfolder_4/PMC3520689_F2_172033.jpg
Summarize the visual content of the image.
Magnetic resonance imaging shows a medullary lesion with low signal intensity on (A) T1- and (B) T2-weighted images. The size of the lesion increased over 10 months (C). Enhancement by gadolinium is seen on the periphery of the lesion on the T1-weighted image (C).
ImageClef-2019-VQA-Med-Training/Train_images/synpic59844.jpg
in what plane is this image taken?
coronal
splits/subfolder_2/PMC3751271_Fig1_226792.jpg
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The degree of muscular connection with a subepithelial tumor as shown by endoscopic ultrasound. A Narrow muscular connection with the tumor: the diameter of the connection with the fourth layer of the tumor is <50 % of the maximal diameter of the tumor base (black arrow hyperechoic demarcation line between the tumor an...
splits/subfolder_5/PMC4332475_pone.0117041.g001_359874.jpg
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In situ hybridization and immunocytochemistry of anion exchanger 1b (AE1b) in zebrafish larvae.AE1b mRNA was expressed by ionocytes (short arrows) and neuromasts (long arrows) of 72-h post-fertilization (hpf) larvae (A, B). No signal was found in larval skin with the sense probe (C). Confocal images of lateral-line n...
splits/subfolder_3/PMC4277822_Fig5_347114.jpg
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Vena contracta measurement. The VC (white arrows) of the MR jet is measured from parasternal long axis view as the narrowest width of the proximal jet at the level of or just distal to the leaflet tips. In this view, the image is zoomed into the area of the VC (arrows), with sector size and depth selected to optimize...
splits/subfolder_3/PMC4502558_Fig5_406111.jpg
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Palmitate induces phospholipid accumulation in RAW 264.7 cells. Cells were treated with 400 μM palmitate or 10 μg/ml tunicamycin for 24 h and then subjected to immunofluorescence using calnexin antibody and LipidTOX Red dye to examine phospholipid accumulation in ER. Green fluorescence indicates calnexin or ER membrane...
splits/subfolder_2/PMC4568913_fig09_423176.jpg
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The mouse myocardial cells, transfected with miR-181c mimic/inhibitor, were intervened with TNF-α and underwent the TEM scan. There were no significant changes in the gross morphology of myocardial cells and the number of mitochondria between groups (A–F, magnification: 4000 ×  to 30000 × ). The mitochondria showed abn...
splits/subfolder_4/PMC3777955_pone-0075727-g003_232600.jpg
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Live-dead assay of mMSC in hydrogels a continuous seven days in culture.A, day 1; B, day 3; C, day 5; D, day 7. The living cells were stained with calcein AM (green) and the dead cells were stained with EthD-1 (red). The images of E and F showed top and side views of a 3D cell-gel construct at day 7, respectively.
splits/subfolder_5/PMC3729245_f3-or-30-01-0035_221656.jpg
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The panel of images represent a single slice from coronal T2-weighted MR images for an animal in each experimental group including saline controls. A diffuse pattern of tumor growth in the peritoneum was visualized on the MR images of saline treated control animals with a reduced pattern in the treatment groups. Perito...
splits/subfolder_4/PMC3495199_F1_165234.jpg
What is shown in this image?
Histomorphometric overview and x-ray after 56 days, for animals from a) uncoated group, b) PDLLA, c) SIM low and d) SIM high. No macroscopic differences were obvious between all 4 groups with regard to implant integration, osteolysis, ectopic bone formation or implant loosening.
splits/subfolder_5/PMC4479609_pone.0128973.g008_399564.jpg
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Tracking with micro-computed tomography.MicroCT images showing localisation of gold-loaded hWJ-MSCs in the right eye (A) at day 1 and it remained in the eye with no further migration systemically at day 30 (B) and day 70 (C) post injection. PKH 26 (labelled red) showed the subretinal location of hWJ-MSCs after the inje...
splits/subfolder_4/PMC3938758_pone-0090433-g003_270752.jpg
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Study of developmental expression of MANF in the cerebral cortex by immunohistochemistry (IHC). A and B: MANF expression in the frontal, parietal and occipital cortex. IHC images were taken from indicated cortical areas shown above. A image of higher magnification showed layers in the cortical cortex (B). C: Double la...
splits/subfolder_4/PMC2944809_ppat-1001120-g003_74378.jpg
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Morphology of intact kidney tissue in Tlr4 −/− and adaptor protein mutant mice infected with CFT073 and ΔTcpC.(A) Overview of htx-eosin stained kidney section of Tlr4−/−, Myd88−/− and Trif −/− mice. Scale bar, 500 µm. (B) Histology of renal cortex stained with specific antibodies to neutrophils (green, NIMP-R14) or the...
splits/sfolder_2/PMC4062402_pone-0097452-g008_299265.jpg
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HE staining of renal tissue at the 8th week of protocol.The black arrows on the micrographies show that tubular vacuolization, in DM+SE were present at proportion of 10∶12. In DM+SE+NAC this proportion was 6∶12, DM+EX and DM+EX+NAC had 04:12. Magnification of x400. CTL+SE, sedentary control; CTL+SE+NAC, sedentary contr...
splits/sfolder_1/PMC4443657_Fig11_389297.jpg
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In situ cell apoptosis detected by TUNEL assay. Rats in the PAN + YQ group received a daily oral gavage of YQQRG. Rats in the sham and PNA groups received the same volume of vehicle (distilled water). 10D, 10 days after PAN injection; 15D, 15 days after PAN injection. Apoptotic cells (arrow) are illustrated in the PA...
splits/subfolder_4/PMC4120005_F3_311064.jpg
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Illustration of the beam configuration used for 3D-CRT and TB-IMRT (A) and 7 F-IMRT (B).
splits/subfolder_4/PMC4616354_F3_435549.jpg
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The vertebral metastases are seen as multiple osteoblastic-osteolytic foci at CT-scan (A). Under microscope, small cells can be observed in the bone marrow (B) that are marked by CD56 (C) and synaptophysin (D). CD = cluster of differentiation, CT = computer-tomography.
splits/subfolder_5/PMC3137635_pone-0022395-g001_102463.jpg
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p44/WDR77 nuclear translocation during mouse prostate development.Immunostaining of p44/WDR77 (left panels, red) in prostate glands derived from mice aged 7, 14, 28, 32, or 45 days. The nucleus was counterstained with SYTOX Green (middle panels, green). The samples were observed under a confocal microscope.
splits/subfolder_4/PMC4260733_fig5_343011.jpg
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Morphological changes caused by ZOL and small G proteins inhibitors. (a) Microphotographs of ZOL-treated cells as indicated (magnification, × 200). (b) Structure of actin fibers in EHMES-10 cells which were treated with ZOL, 1 μg/ml C3 transferase, 5 μM GGTI-298 or 1 mM NE10790 for 24 h and were stained with Alexa Fluo...
splits/subfolder_2/PMC3832393_pone-0080552-g001_244242.jpg
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Representative microscopic views of PA1 staining with rabbit polyclonal antibody against PA1.a, nuclear staining; b, cytoplasmic staining; c, mixed nuclear and cytoplasmic staining; d, negative staining (original magnification × 400) e, histograms for Histo-Score (HS) of PA1-nuc and f, of PA1-cyto (mean; 51.4, S.D.; 62...
splits/sfolder_2/PMC3338626_pone-0036047-g004_135897.jpg
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rs12676 TT genotype is associated with dysmorphic mitochondrial structure in sperm.Sperm were fixed and processed for transmission electron microscopy as described in the Methods section. Longitudinal and cross-sectional sections of sperm were examined for mitochondria structure anomalies. Representative images for rs1...
splits/subfolder_4/PMC3983215_pone-0094595-g004_280348.jpg
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Lung tumors uniformly express Jenv and SPC irrespective of Akt isoform status.Immunostaining for Jenv, SPC, and CC10 expression in lung tissue from AJEJJenv infected WT (A to C), Akt1−/− (D to F), Akt2−/− (G to I), and Akt3−/− (J to L) mice at 10× magnification. Representative images of advanced neoplastic lesions show...
splits/subfolder_3/PMC4230930_pntd-0003309-g007_335947.jpg
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Sub-cellular localization of ENTPDases in L. infantum chagasi promastigotes.Electron micrographs using polyclonal antibodies to rLicNTPDase-2 anti-IgG conjugated to 10 nm colloidal gold (A–H). Letters and symbols indicate different localizations: nucleus (N) (white arrow), mitochondria and kinetoplasts (K) (white arrow...
splits/subfolder_5/PMC2386509_f1_22750.jpg
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Expression of P2X7 receptor on human conjunctival and corneal epithelial cells. Conjunctival cell line (A), corneal cell line (B) and cells from ocular surface impression cytology (C) presented P2X7 receptor expression. Cells were fixed, permeabilized, and then incubated with a P2X7 antibody. Nuclei were stained with p...
roco-dataset/data/train/radiology/images/ROCO_19907.jpg
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ICG angiography of right breast taken immediately postoperatively of same patient who developed bilateral partial nipple necrosis postoperatively.
splits/subfolder_2/PMC3548173_F1_179854.jpg
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The morphology of salivary gland and liver progenitor cells under 2D and 3D cultivation conditions, phase contrast microscopy. A) PSGC, monolayer culture, 0 passage; B) PLPC, monolayer culture, 0 passage; C) PSGC, 10-th day of cultivation in 4% collagen gel, 1 passage; D) PLPC, 10th day of cultivation in 4% collage...
splits/subfolder_5/PMC3695963_pone-0068362-g001_214548.jpg
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Ectopic expression of aromatase in embryonic gonads.RCASBP-Aromatase virus was injected into blastoderms and aromatase expression was assessed at embryonic day 10.5 by immunostaining (10×magnification). For each, the left (Lg) and right (Rg) gonads are shown with aromatase staining (green). No expression was detected i...
splits/subfolder_5/PMC4262501_f2-mmr-11-02-0805_343450.jpg
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Effect of APE on the tissue morphology of fibrotic rat liver as indicated by hematoxylin and eosin staining (magnification, ×100). (A) Normal group, liver sections showed normal hepatic cells with well preserved cytoplasm, prominent nucleolus and central vein. (B) Model group, liver sections showed fatty acid degenerat...
splits/subfolder_2/PMC2965754_pgen-1001142-g009_77329.jpg
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Ultrastructural Analysis of Ntrk3 Mutant Kidneys.Kidneys from Ntrk3−/− (′) and control littermates at 4 days of age were examined by scanning (A, B) and transmission electron microscopy (C, D). A, B) Note the disorganized patterning and irregularly shaped primary and secondary foot processes. C, D) Note the fusion of f...