protein_id stringlengths 6 10 | protein_names stringlengths 2 1.26k | protein_function stringlengths 9 5.75k ⌀ | organism stringclasses 589
values | length float64 11 16k | subcellular_location stringlengths 7 6.16k ⌀ | sequence stringlengths 11 16k | go_ids listlengths 2 494 | go_bp listlengths 0 437 ⌀ | go_mf listlengths 0 59 ⌀ | go_cc listlengths 0 67 ⌀ | structure_path stringlengths 25 29 ⌀ | string_id stringlengths 10 27 ⌀ | interaction_partners listlengths 1 668 ⌀ | interpro_ids listlengths 1 20 ⌀ | interpro_location stringlengths 3 529 | ppi_formatted stringlengths 0 811 | interpro_formatted stringlengths 0 1.79k | go_pred stringlengths 369 15k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Q13542 | Eukaryotic translation initiation factor 4E-binding protein 2 | Repressor of translation initiation involved in synaptic plasticity, learning and memory formation. Regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form of EIF4EBP2 competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperp... | Homo sapiens (Human) | 120 | Cytoplasm. Nucleus | MSSSAGSGHQPSQSRAIPTRTVAISDAAQLPHDYCTTPGGTLFSTTPGGTRIIYDRKFLLDRRNSPMAQTPPCHLPNIPGVTSPGTLIEDSKVEVNNLNNLNNHDRKHAVGDDAQFEMDI | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0032838",
"GO:0035770",
"GO:0036464",
"GO:0042995",
"GO:0043005",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0071598",
"GO:0099080",
"GO:0099568",
"GO:0110165",
"GO:0120025",
"GO:0120111"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0032838",
"GO:0035770",
"GO:0036464",
"GO:0042995",
"GO:0043005",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0071598",
"GO:0099080",
"GO:0099568",
"GO:0110165",
"GO:0120025",
"GO:0120111"
] | AF-Q13542-F1-model_v6.pdb | 9606.ENSP00000362314 | [
"Q96E95",
"Q8N102",
"Q9P2P3",
"O60516",
"Q6IBN3",
"Q7Z721",
"Q9Y4I3"
] | [
"IPR008606"
] | {"IPR008606": [7, 120]} | - Eukaryotic translation initiation factor 4E
- Regulatory-associated protein of mTOR
- Serine/threonine-protein kinase mTOR
- Eukaryotic translation initiation factor 4E-binding protein 1
- Eukaryotic translation initiation factor 4E-binding protein 3
- Ribosomal protein S6 kinase beta-1
- Eukaryotic translation initi... | - IPR008606: Eukaryotic translation initiation factor 4E binding (family) [7-120] | Molecular Function (MF): GO:0003674 (molecular function), GO:0045182 (translation regulator activity), GO:0005488 (binding), GO:0030371 (translation repressor activity), GO:0005515 (protein binding), GO:0031369 (translation initiation factor binding), GO:0008190 (eukaryotic initiation factor 4E binding)
Biological Proc... |
P97288 | 5-hydroxytryptamine receptor 4 | G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (By similarity). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide- binding proteins (G proteins) and modulates the activity of downst... | Mus musculus (Mouse) | 388 | Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Interaction with SNX27 mediates recruitment to early endosomes, while interaction with NHERF1 and EZR might target the protein to specialized subcellular regions, such as microvilli | MDKLDANVSSNEGFRSVEKVVLLTFLAVVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWAYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVLPMFISFLPIMQGWNNIGIVDVIEKRKFSHNSNSTWCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQPADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEQVWTAFLWLGYINSGLNPFLYAFLNKSFR... | [
"GO:0001894",
"GO:0003008",
"GO:0006810",
"GO:0007154",
"GO:0007165",
"GO:0007186",
"GO:0007586",
"GO:0007589",
"GO:0008150",
"GO:0009987",
"GO:0010669",
"GO:0022600",
"GO:0023052",
"GO:0030277",
"GO:0032501",
"GO:0032941",
"GO:0042592",
"GO:0044087",
"GO:0046903",
"GO:0048871"... | [
"GO:0001894",
"GO:0003008",
"GO:0006810",
"GO:0007154",
"GO:0007165",
"GO:0007186",
"GO:0007586",
"GO:0007589",
"GO:0008150",
"GO:0009987",
"GO:0010669",
"GO:0022600",
"GO:0023052",
"GO:0030277",
"GO:0032501",
"GO:0032941",
"GO:0042592",
"GO:0044087",
"GO:0046903",
"GO:0048871"... | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0030054",
"GO:0045202",
"GO:0071944",
"GO:0098794",
"GO:0098978",
"GO:0110165"
] | AF-P97288-F1-model_v6.pdb | 10090.ENSMUSP00000027560 | [
"Q61226",
"O70176",
"Q9R1C8",
"Q3UFE9",
"Q544U4",
"Q9D887",
"Q9Z1N8",
"Q8CGK7",
"Q5FW59",
"Q9QUN1",
"Q14A50"
] | [
"IPR017452",
"IPR001520",
"IPR000276"
] | {"IPR001520": [2, 359], "IPR000276": [21, 327], "IPR017452": [36, 312]} | - Guanine nucleotide-binding protein G(olf) subunit alpha
- VIP peptides
- VIP peptides
- Pro-opiomelanocortin
- 5-hydroxytryptamine receptor 6
- 5-hydroxytryptamine receptor 7
- Gastric inhibitory polypeptide
- Pro-glucagon
- Pituitary adenylate cyclase-activating polypeptide
- Natriuretic peptides A | - IPR017452: GPCR, rhodopsin-like, 7TM (domain) [36-312]
- IPR001520: 5-Hydroxytryptamine 4 receptor (family) [2-359]
- IPR000276: G protein-coupled receptor, rhodopsin-like (family) [21-327] | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity), GO:0004888 (transmembrane signaling receptor activity), GO:0099589 (serotonin receptor activity), GO:0004930 (G protein-coupled receptor activity), GO:0008227 (G protein-couple... |
Q7ZWC3 | Oxidized purine nucleoside triphosphate hydrolase | Oxidized purine nucleoside triphosphate hydrolase which is a prominent sanitizer of the oxidized nucleotide pool. Catalyzes the hydrolysis of 2-oxo-dATP (2-hydroxy- dATP) into 2-oxo-dAMP. Also has a significant hydrolase activity toward 2-oxo-ATP, 8-oxo-dGTP and 8-oxo-dATP. Through the hydrolysis of oxidized purine nuc... | Danio rerio (Zebrafish) (Brachydanio rerio) | 156 | Cytoplasm, cytosol. Mitochondrion matrix. Nucleus | MFTSKLLTLVLVVQPGRVLLGMKKRGFGAGKWNGFGGKVQTGETIEQAARRELLEESGLTVDTLHKIGNIKFEFIGETELMDVHIFRADNYEGEPAESDEMRPQWFDIDKIPFSQMWADDILWFPLMLQKKRFLGYFKFQGHDVIVEHKLDEVEDL | [
"GO:0006139",
"GO:0006163",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009117",
"GO:0009151",
"GO:0009262",
"GO:0009394",
"GO:0009987",
"GO:0019637",
"GO:0044238",
"GO:0044281",
"GO:0055086",
"GO:0072521",
"GO:1901135"
] | [
"GO:0006139",
"GO:0006163",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009117",
"GO:0009151",
"GO:0009262",
"GO:0009394",
"GO:0009987",
"GO:0019637",
"GO:0044238",
"GO:0044281",
"GO:0055086",
"GO:0072521",
"GO:1901135"
] | [] | [] | AF-Q7ZWC3-F1-model_v6.pdb | 7955.ENSDARP00000040752 | [
"Q6IQ66",
"E7F6K6",
"Q568Q0",
"Q1LXZ5",
"A0A2R8RL21",
"B0R135",
"Q6DG97",
"Q4V8V2",
"A0A0R4ISD4",
"F1QQK5"
] | [
"IPR020084",
"IPR003563",
"IPR000086",
"IPR020476",
"IPR015797"
] | {"IPR015797": [1, 147], "IPR003563": [4, 154], "IPR000086": [3, 129], "IPR020476": [32, 61], "IPR020084": [37, 58]} | - 8-oxo-dGDP phosphatase NUDT18
- Nucleotide triphosphate diphosphatase NUDT15
- ADP-sugar pyrophosphatase
- m7GpppN-mRNA hydrolase NUDT17
- Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]
- Uridine diphosphate glucose pyrophosphatase NUDT14
- Nudix (nucleoside diphosphate-linked moiety X)-type motif 22
- N-glycosyla... | - IPR020084: NUDIX hydrolase, conserved site (conserved_site) [37-58]
- IPR003563: Oxidized purine nucleoside triphosphate (family) [4-154]
- IPR000086: NUDIX hydrolase domain (domain) [3-129]
- IPR020476: NUDIX hydrolase (domain) [32-61]
- IPR015797: NUDIX hydrolase-like domain superfamily (homologous_superfamily) [1-... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016817 (hydrolase activity, acting on acid anhydrides), GO:0016818 (hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)
Biological Process (BP): GO:0008150 (bio... |
Q568L5 | Aldo-keto reductase family 1 member A1-B | Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids. Acts as an aldehyde-detoxification enzyme (By similari... | Danio rerio (Zebrafish) (Brachydanio rerio) | 324 | Cytoplasm, cytosol. Apical cell membrane | MNDFAVLSTGRKMPLLGLGTWKSEPGLVKQAVIWALESGYRHIDCAPIYANEPEIGEAFQETMGPDKGIRREDVFVTSKLWNTKHHPDDVEPSLLKTLKDLKLEYLDLYLIHWPYAFQRGDTPFPRKEDGTLLYDDIDYKLTWAAMEKLVGKGLVRAIGLSNFNSRQIDDILSVASIKPTVLQVESHPYLAQVELLSHCRDRGLVMTAYSPLGSPDRAWKHPDEPVLLEEPAIAALAKKYNKTPAQIIIRWQTQRGVVTIPKSITQSRIKENIQVFDFTLESEEMSQVTALHRGWRYIVPTITVDGKSVPRDAGHPHYPF... | [
"GO:0006109",
"GO:0006111",
"GO:0008150",
"GO:0009889",
"GO:0010906",
"GO:0019222",
"GO:0033500",
"GO:0042592",
"GO:0042593",
"GO:0043255",
"GO:0048878",
"GO:0050789",
"GO:0050794",
"GO:0062012",
"GO:0065007",
"GO:0080090",
"GO:0003674",
"GO:0003824",
"GO:0008106",
"GO:0016491"... | [
"GO:0006109",
"GO:0006111",
"GO:0008150",
"GO:0009889",
"GO:0010906",
"GO:0019222",
"GO:0033500",
"GO:0042592",
"GO:0042593",
"GO:0043255",
"GO:0048878",
"GO:0050789",
"GO:0050794",
"GO:0062012",
"GO:0065007",
"GO:0080090"
] | [
"GO:0003674",
"GO:0003824",
"GO:0008106",
"GO:0016491",
"GO:0016614",
"GO:0016616",
"GO:0018455"
] | [] | AF-Q568L5-F1-model_v6.pdb | 7955.ENSDARP00000119785 | [
"Q90ZZ8",
"B8A4B0",
"Q6P696",
"F6NZ60",
"A2BGR9",
"B0S7W5",
"Q7ZVB2",
"F8W5X0",
"B0UYA3",
"F8W5X3",
"Q6AZW2",
"Q90ZZ7",
"E9QH31",
"F1QGS9",
"F1QR17",
"Q4V8T0",
"F2Z4R7",
"F1QGP1",
"Q7ZWC2",
"X1WBM4",
"A0A2R8RIE8",
"Q802W2"
] | [
"IPR044481",
"IPR023210",
"IPR018170",
"IPR020471",
"IPR036812"
] | {"IPR036812": [2, 324], "IPR020471": [5, 307], "IPR044481": [7, 311], "IPR023210": [16, 291], "IPR018170": [39, 275]} | - Aldehyde dehydrogenase
- Beta-glucuronidase
- Glucuronokinase with putative uridyl pyrophosphorylase
- Klotho
- Monoglyceride lipase
- Aldo-keto reductase family 1 member A1-A
- Inositol oxygenase
- Aldehyde dehydrogenase
- Lactoylglutathione lyase
- Aldehyde dehydrogenase | - IPR044481: Aldo-keto reductase family 1 member A1 (family) [7-311]
- IPR023210: NADP-dependent oxidoreductase domain (domain) [16-291]
- IPR018170: Aldo/keto reductase, conserved site (conserved_site) [39-275]
- IPR020471: Aldo-keto reductase (family) [5-307]
- IPR036812: NAD(P)-dependent oxidoreductase domain superf... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (B... |
P31037 | Protein A49R | Plays a role in the inhibition of host NF-kappa-B activation. Interacts with host BTRC and thereby diminishes ubiquitination of NF- kappa-B inhibitor alpha/NFKBIA. This stabilizes NFKBIA and its interaction with NF-kappaB, so retaining p65/RELA in the cytoplasm and preventing NF-kappa-B-dependent gene expression | Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain | 162 | Host cytoplasm. Host nucleus | MDEAYYSGNLESVLGYVSDMHTELASISQLVIAKIETIDNDILNKDIVNFIMCRSNLDNPFISFLDTVYTIIDQENYQTELINSLDDNEIIDCIVNKFMSFYKDNLENIVDAIITLKYIMNNPDFKTTYAEVLGSRIADIDIKQVIRENILQLSNDIRERYL | [
"GO:0007154",
"GO:0007165",
"GO:0008150",
"GO:0009987",
"GO:0023052",
"GO:0035556",
"GO:0035821",
"GO:0038061",
"GO:0044003",
"GO:0044068",
"GO:0044403",
"GO:0044419",
"GO:0050789",
"GO:0050794",
"GO:0050896",
"GO:0051701",
"GO:0051716",
"GO:0052027",
"GO:0052029",
"GO:0065007"... | [
"GO:0007154",
"GO:0007165",
"GO:0008150",
"GO:0009987",
"GO:0023052",
"GO:0035556",
"GO:0035821",
"GO:0038061",
"GO:0044003",
"GO:0044068",
"GO:0044403",
"GO:0044419",
"GO:0050789",
"GO:0050794",
"GO:0050896",
"GO:0051701",
"GO:0051716",
"GO:0052027",
"GO:0052029",
"GO:0065007"... | [
"GO:0003674",
"GO:0140311",
"GO:0140313"
] | [
"GO:0005575",
"GO:0018995",
"GO:0030430",
"GO:0033643",
"GO:0033646",
"GO:0043656",
"GO:0044217",
"GO:0110165"
] | null | null | null | [
"IPR009473"
] | {"IPR009473": [1, 162]} | - IPR009473: Orthopoxvirus A49 (family) [1-162] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0016032 (viral process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO... | |
Q01220 | Protein A52 | Bcl-2-like protein which targets host toll-like receptor signaling complexes to suppress innate immune response. Interacts with host TRAF6 to activate p38 and subsequently induce the expression of several cytokines such as IL-10. Also associates with host IRAK2 to inhibit NF-kappa-B signaling | Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain | 190 | null | MDIKIDISISGDKFTVTTRRENEERKKYLPLQKEKTTDVIKPDYLEYDDLLDRDEMFTILEEYFMYRGLLGLRIKYGRLFNEIKKFDNDAEEQFGTIEELKQKLRLNSEEGADNFIDYIKVQKQDIVKLTVYDCISMIGLCACVVDVWRNEKLFSRWKYCLRAIKLFINDHMLDKIKSILQNRLVYVEMS | [
"GO:0007154",
"GO:0007165",
"GO:0007249",
"GO:0008150",
"GO:0009987",
"GO:0023052",
"GO:0035556",
"GO:0035821",
"GO:0038061",
"GO:0044003",
"GO:0044068",
"GO:0044403",
"GO:0044419",
"GO:0050789",
"GO:0050794",
"GO:0050896",
"GO:0051701",
"GO:0051716",
"GO:0052027",
"GO:0052029"... | [
"GO:0007154",
"GO:0007165",
"GO:0007249",
"GO:0008150",
"GO:0009987",
"GO:0023052",
"GO:0035556",
"GO:0035821",
"GO:0038061",
"GO:0044003",
"GO:0044068",
"GO:0044403",
"GO:0044419",
"GO:0050789",
"GO:0050794",
"GO:0050896",
"GO:0051701",
"GO:0051716",
"GO:0052027",
"GO:0052029"... | [] | [
"GO:0005575",
"GO:0018995",
"GO:0030430",
"GO:0033643",
"GO:0033646",
"GO:0043656",
"GO:0044217",
"GO:0110165"
] | null | null | null | [
"IPR043018",
"IPR022819"
] | {"IPR043018": [36, 190], "IPR022819": [20, 174]} | - IPR043018: Poxvirus domain superfamily (homologous_superfamily) [36-190]
- IPR022819: Poxvirus Bcl-2-like (family) [20-174] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... | |
Q59RR0 | Cell wall transcription factor ACE2 | Transcription factor involved in the RAM (regulation of ACE2 transcription factor and polarized morphogenesis) signaling network that regulates polarized morphogenesis. Regulates expression of genes involved in cell separation such as CHT3, DSE1, and SCW11; or other cell wall genes such as ASH1, DSE4, PIR1, PRY2, and R... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 783 | Nucleus. Note=Localized in the nuclei of daughter cells | MHWKFSNFRKYHLSFHLNLFDLSLFFISFYCFPILYICFFNQVHSFRSTQPSLIMNKFDLFDDYSTKGSTIPLPNENFDQLFLSSEANDMEFLFNETLMGLQDLDVPSGYGIPQNTINNDFQHTPNKSKSHSRQYSGTAIFGFADHNKDLSINGVNNDLCKQSNKAINTQSVSPGELLKRSRGSQTPTPTSALPDTAQDILDFNFEEKPILLLEEDELEEEKHKQQQRMMTQSSPLKRVTTPSQSPFVQQPQTMKQRKPHKKTNEYIVANENPNSYKFPPSPSPTAKRQQYPPSSPIPYNPKSDSVGGNSYSAKYLQSLN... | [
"GO:0006355",
"GO:0006357",
"GO:0007155",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010564",
"GO:0010570",
"GO:0010604",
"GO:0010810",
"GO:0010811",
"GO:0016043",
"GO:0019219",
"GO:0019222",
"GO:0030155"... | [
"GO:0006355",
"GO:0006357",
"GO:0007155",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010564",
"GO:0010570",
"GO:0010604",
"GO:0010810",
"GO:0010811",
"GO:0016043",
"GO:0019219",
"GO:0019222",
"GO:0030155"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q59RR0-F1-model_v6.pdb | 237561.Q59RR0 | [
"Q5ACY4",
"Q59U34",
"Q5AP53",
"Q5ABC6"
] | [
"IPR013087",
"IPR036236"
] | {"IPR036236": [647, 701], "IPR013087": [649, 706]} | - Serine/threonine-protein kinase CBK1
- Cdh1p
- CBK1 kinase activator protein MOB2
- Biofilm and cell wall regulator 1 | - IPR013087: Zinc finger C2H2-type (domain) [649-706]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [647-701] | Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biolog... |
P83773 | Acetyl-CoA hydrolase | Presumably involved in regulating the intracellular acetyl- CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 524 | Cytoplasm | MSAILKQRVRYAPYLKKLRTGEQCIDLFKHGQYLGWSGFTGVGAPKVIPTTLVDHVEKNNLQGKLGFHLFVGASAGPEESRWAENNMILTRAPHQVGKPIAAAINDGRTQFFDKHLSMFPQDLTYGFYTKDKPNGSNLDYTIIEATAITEDGSIVPGPAVGASPEMISVSDKIIIEVNTKTPSFEGIHDIDMPVNPPFRQPYPHTSADFKIGKTAIPVDPEKVVAIVESTSGDKVPPNTPSDEQSRGIANHLIEFLEHEVKQGRLPANLHPLQSGIGNIANAVVEGLASSNFKNLTVWTEVLQDSFLDFFESGSLDYATA... | [
"GO:0006082",
"GO:0006083",
"GO:0008150",
"GO:0008152",
"GO:0009268",
"GO:0009628",
"GO:0009987",
"GO:0010446",
"GO:0019752",
"GO:0032787",
"GO:0043436",
"GO:0044281",
"GO:0050896",
"GO:0051716",
"GO:0071214",
"GO:0071467",
"GO:0071469",
"GO:0104004",
"GO:0003674",
"GO:0003824"... | [
"GO:0006082",
"GO:0006083",
"GO:0008150",
"GO:0008152",
"GO:0009268",
"GO:0009628",
"GO:0009987",
"GO:0010446",
"GO:0019752",
"GO:0032787",
"GO:0043436",
"GO:0044281",
"GO:0050896",
"GO:0051716",
"GO:0071214",
"GO:0071467",
"GO:0071469",
"GO:0104004"
] | [
"GO:0003674",
"GO:0003824",
"GO:0003986",
"GO:0016289",
"GO:0016787",
"GO:0016788",
"GO:0016790",
"GO:0160215"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005739",
"GO:0005829",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-P83773-F1-model_v6.pdb | 237561.P83773 | [
"Q5AH20",
"Q8NJN3",
"Q59TC4",
"A0A1D8PH52",
"A0A1D8PSH3",
"Q5AB86",
"Q5AGX8",
"A0A1D8PRR7",
"Q9P8Q2",
"A0A1D8PTB5",
"A0A1D8PM94",
"A0A1D8PSW6",
"A0A1D8PIF8",
"Q59XW4",
"A0A1D8PH13",
"Q59VG1",
"A0A1D8PC76",
"A0A1D8PGT5",
"Q5A8X6",
"A0A1D8PNQ8"
] | [
"IPR003702",
"IPR038460",
"IPR026888",
"IPR037171",
"IPR046433"
] | {"IPR037171": [6, 516], "IPR038460": [350, 496], "IPR046433": [2, 520], "IPR003702": [10, 228], "IPR026888": [329, 479]} | - Acetyl-coenzyme A synthetase 2
- Malate synthase
- Acetyl-coenzyme A synthetase
- Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial
- Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial
- Acetyl-CoA acetyltransferase
- Aldehyde dehydrogenase (NAD(P)(+))
- Acetyltransferase component of pyru... | - IPR003702: Acetyl-CoA hydrolase/transferase, N-terminal (domain) [10-228]
- IPR038460: Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily (homologous_superfamily) [350-496]
- IPR026888: Acetyl-CoA hydrolase/transferase, C-terminal domain (domain) [329-479]
- IPR037171: NagB/RpiA transferase-like (homolog... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0016782 (transferase activity, transferring sulphur-containing groups), GO:0008410 (CoA-transferase ac... |
Q4V9P6 | N6-Methyl-AMP deaminase | Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A) | Danio rerio (Zebrafish) (Brachydanio rerio) | 348 | null | MDTEADLFYRQLPKVELHAHLNGSVSFETMEKLIKRKPHLNIEHSMTAIRRGQRRTLDECFQVFKVIHQLVDSEEDILMVAKSVIQEFAADGVKYLELRSTPREVTETGLSKQRYIETVLEAIRQCKQEGVDIDVRFLVAVDRRHGPEVAMQTVKLAEDFLLSSDGTVVGLDLSGDPTVGHGKDLLAALQKAKNCGLKLALHLSEVPSQIDETELLLNLPPDRIGHGTFLHPDVGGSDSLVDKVCKQNIPIEICLTSNVKGQTVPSYDKHHFKYWYNRGHPCVLCTDDKGVFCTDLSQEYQLAASTFGLTKEAVWILSQQ... | [
"GO:0001654",
"GO:0007275",
"GO:0007423",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0043010",
"GO:0048513",
"GO:0048731",
"GO:0048856",
"GO:0048880",
"GO:0150063"
] | [
"GO:0001654",
"GO:0007275",
"GO:0007423",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0043010",
"GO:0048513",
"GO:0048731",
"GO:0048856",
"GO:0048880",
"GO:0150063"
] | [] | [] | AF-Q4V9P6-F1-model_v6.pdb | 7955.ENSDARP00000067287 | [
"A0A0G2KGL2",
"Q6ZM69",
"F8W4R3",
"A0A0R4ISR7",
"F1QG13"
] | [
"IPR006330",
"IPR032466",
"IPR001365"
] | {"IPR032466": [8, 342], "IPR006330": [9, 345], "IPR001365": [13, 336]} | - IPR006330: Adenosine/adenine deaminase (family) [9-345]
- IPR032466: Metal-dependent hydrolase (homologous_superfamily) [8-342]
- IPR001365: Adenosine deaminase domain (domain) [13-336] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016810 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds), GO:0016814 (hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines), GO:00192... | |
P05552 | Transcription factor Adf-1 | May play an important role not only in the regulation of Adh expression but also in the transcription of other genes | Drosophila melanogaster (Fruit fly) | 262 | Nucleus | MHTLTAAIEMDKLDANLEQQFDLNLIEAVKLNPVIYDRSHYNYKHFVRKAQTWKQIAETLGVPEQKCTKRWKSLRDKFAREMKLCQESRWRYFKQMQFLVDSIRQYRESLLGKCANGSQSANQVADPSQQQQAQQQTVVDIFAQPFNGSATTSAQALTHPHEITVTSDAQLATAVGKDQKPYFYEPPLKRERSEEEHSDNMLNTIKIFQNNVSQAVSAEDQSFGMVVTDMLNTLGVRQKAEAKVHIIKYLTDMQLLAQHNKY | [
"GO:0006355",
"GO:0006357",
"GO:0008150",
"GO:0009889",
"GO:0010468",
"GO:0010556",
"GO:0019219",
"GO:0019222",
"GO:0050789",
"GO:0050794",
"GO:0051252",
"GO:0060255",
"GO:0065007",
"GO:0080090",
"GO:2001141",
"GO:0000976",
"GO:0000981",
"GO:0001067",
"GO:0003674",
"GO:0003676"... | [
"GO:0006355",
"GO:0006357",
"GO:0008150",
"GO:0009889",
"GO:0010468",
"GO:0010556",
"GO:0019219",
"GO:0019222",
"GO:0050789",
"GO:0050794",
"GO:0051252",
"GO:0060255",
"GO:0065007",
"GO:0080090",
"GO:2001141"
] | [
"GO:0000976",
"GO:0000981",
"GO:0001067",
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003690",
"GO:0003700",
"GO:0005488",
"GO:0043565",
"GO:0140110",
"GO:1990837"
] | [] | AF-P05552-F1-model_v6.pdb | 7227.FBpp0303284 | [
"Q9VUH2"
] | [
"IPR039353",
"IPR006578",
"IPR004210"
] | {"IPR039353": [16, 260], "IPR006578": [24, 104], "IPR004210": [217, 256]} | - Transcription activator GAGA | - IPR039353: Transcription factor Adf-1 (family) [16-260]
- IPR006578: MADF domain (domain) [24-104]
- IPR004210: BESS motif (domain) [217-256] | Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0001216 (DNA-binding transcription activator activity), GO:0000981 (DNA-binding transcription factor activity, RNA polymerase II-specific), GO:0001228 (DNA-... |
Q5AF56 | Transcriptional regulator ADR1 | Transcription factor involved in the regulation of hyphal growth | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,418 | Nucleus | MISPTHQSQYLNYFVNPVLMTESGDIIDSVTGTTTTTANMSNTTIDAPTPASTTKNYKHKKQNTNTGTSMSPSNSINSTNNNAAAAAATTTTSKKSKDIPLELTAFGTTPSGKPRLFVCQVCTRAFARLEHLRRHERSHTKEKPFSCGVCQRKFSRRDLLLRHAQKLHAGCTDAITRLRRKSIKKSQDGDDDDDDDDDDEEMANSEDENDHDESGNASTKNGKKDKKDPPPEFNLNLFNSKQKPTKANTTKSKVAKLSTTTSRKNSTNPTRKNSSSLHKQVLDQRQKAAVNTKIVSSTKIVSGTNSGVSITPTRSRRGAS... | [
"GO:0006066",
"GO:0006109",
"GO:0006629",
"GO:0006694",
"GO:0006696",
"GO:0006950",
"GO:0006996",
"GO:0007031",
"GO:0008150",
"GO:0008152",
"GO:0008202",
"GO:0008204",
"GO:0008610",
"GO:0009058",
"GO:0009267",
"GO:0009607",
"GO:0009987",
"GO:0016043",
"GO:0016125",
"GO:0016126"... | [
"GO:0006066",
"GO:0006109",
"GO:0006629",
"GO:0006694",
"GO:0006696",
"GO:0006950",
"GO:0006996",
"GO:0007031",
"GO:0008150",
"GO:0008152",
"GO:0008202",
"GO:0008204",
"GO:0008610",
"GO:0009058",
"GO:0009267",
"GO:0009607",
"GO:0009987",
"GO:0016043",
"GO:0016125",
"GO:0016126"... | [
"GO:0001216",
"GO:0003674",
"GO:0003700",
"GO:0140110"
] | [] | AF-Q5AF56-F1-model_v6.pdb | 237561.Q5AF56 | [
"A0A1D8PN61",
"Q5A766"
] | [
"IPR013087",
"IPR051059",
"IPR036236"
] | {"IPR036236": [114, 163], "IPR051059": [98, 1403], "IPR013087": [117, 173]} | - DNA-binding transcription factor
- Carbon catabolite-derepressing protein kinase | - IPR013087: Zinc finger C2H2-type (domain) [117-173]
- IPR051059: Transcription factor verF-like (family) [98-1403]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [114-163] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), ... |
Q9D1K7 | Adipose-secreted signaling protein | Adipocyte-secreted protein (adipokine) that acts as a key regulator for white adipose tissue (WAT) thermogenesis and glucose homeostasis at least in part through activation of protein kinase A (PKA) | Mus musculus (Mouse) | 174 | Secreted | MAAANRGSKPRVRSIRFAAGHDAEGSQSHVHFDEKLHDSVVMVTQESDNSFLVKVGFLKILHRYEITFTLPPVRRLSKDIRETPVHSLHLKLLSVTPTSEGYSIKCEYSAHKEGVLKEEMLLACEGDIGTCVRVTVQARVMDRHHGTPMLLDGVKCVGAELEYDSEQSDWLGFD | [
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0033500",
"GO:0042592",
"GO:0042593",
"GO:0048878",
"GO:1990845",
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0110165"
] | [
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0033500",
"GO:0042592",
"GO:0042593",
"GO:0048878",
"GO:1990845"
] | [] | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0110165"
] | AF-Q9D1K7-F1-model_v6.pdb | 10090.ENSMUSP00000028800 | null | [
"IPR026794"
] | {"IPR026794": [1, 174]} | - IPR026794: Adipose-secreted signaling protein (family) [1-174] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0019902 (phosphatase binding), GO:0019903 (protein phosphatase binding), GO:0008157 (protein phosphatase 1 binding)
Biological Process (BP): GO:0008150 (biological process), GO:0... | |
P37127 | Putative oxidoreductase AegA | Involved in formate-dependent uric acid degradation under microaerobic and anaerobic conditions. May reduce the enzymes necessary for uric acid degradation | Escherichia coli (strain K12) | 659 | null | MNRFIMANSQQCLGCHACEIACVMAHNDEQHVLSQHHFHPRITVIKHQQQRSAVTCHHCEDAPCARSCPNGAISHVDDSIQVNQQKCIGCKSCVVACPFGTMQIVLTPVAAGKVKATAHKCDLCAGRENGPACVENCPADALQLVTDVALSGMAKSRRLRTARQEHQPWHASTAAQEMPVMSKVEQMQATPARGEPDKLAIEARKTGFDEIYLPFRADQAQREASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITGRVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDL... | [
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0019628",
"GO:0044281",
"GO:0044282",
"GO:0046415",
"GO:0072521",
"GO:0072523"
] | [
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0019628",
"GO:0044281",
"GO:0044282",
"GO:0046415",
"GO:0072521",
"GO:0072523"
] | [] | [] | AF-P37127-F1-model_v6.pdb | 511145.b2468 | [
"Q2MAT2",
"Q2M900",
"P78239",
"Q2M6M5"
] | [
"IPR006006",
"IPR017900",
"IPR009051",
"IPR023753",
"IPR017896",
"IPR036188",
"IPR028261"
] | {"IPR009051": [161, 326], "IPR036188": [327, 651], "IPR006006": [187, 653], "IPR017896": [54, 145], "IPR028261": [205, 315], "IPR023753": [329, 640], "IPR017900": [87, 98]} | - Glutamate synthase [NADPH] large chain
- NAD-dependent dihydropyrimidine dehydrogenase subunit PreA
- Formate dehydrogenase H
- NADH-quinone oxidoreductase subunit F | - IPR006006: Glutamate synthase NADPH small chain-like (family) [187-653]
- IPR017900: 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (conserved_site) [87-98]
- IPR009051: Alpha-helical ferredoxin (homologous_superfamily) [161-326]
- IPR023753: FAD/NAD(P)-binding domain (domain) [329-640]
- IPR017896: 4Fe-4S f... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0009055 (electron transfer activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:000998... |
Q8TGA2 | Fatty acid synthase alpha subunit aflA | Fatty acid synthase alpha subunit; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide- derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatox... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 1,671 | null | MVIQGKRLAASSIQLLASSLDAKKLCYEYDERQAPGVTQITEEAPTEQPPLSTPPSLPQTPNISPISASKIVIDDVALSRVQIVQALVARKLKTAIAQLPTSKSIKELSGGRSSLQNELVGDIHNEFSSIPDAPEQILLRDFGDANPTVQLGKTSSAAVAKLISSKMPSDFNANAIRAHLANKWGLGPLRQTAVLLYAIASEPPSRLASSSAAEEYWDNVSSMYAESCGITLRPRQDTMNEDAMASSAIDPAVVAEFSKGHRRLGVQQFQALAEYLQIDLSGSQASQSDALVAELQQKVDLWTAEMTPEFLAGISPMLDV... | [
"GO:0005575",
"GO:0005835",
"GO:0032991",
"GO:0140535",
"GO:1902494",
"GO:1990234"
] | [] | [] | [
"GO:0005575",
"GO:0005835",
"GO:0032991",
"GO:0140535",
"GO:1902494",
"GO:1990234"
] | AF-Q8TGA2-F1-model_v6.pdb | 1403190.Q8TGA2 | [
"A0A0F0IGH1",
"A0A0F0HZD0",
"A0A0F0IN54",
"A0A0F0I3U8",
"A0A0F0ILF1",
"A0A0F0IHY3",
"A0A0F0I549",
"A0A0F0I494",
"A0A0F0IK72",
"A0A0F0HZA4",
"A0A0F0III1",
"Q8TGA1",
"A0A0F0ILA6"
] | [
"IPR036291",
"IPR040899",
"IPR008278",
"IPR020841",
"IPR018201",
"IPR016039",
"IPR009081",
"IPR047224",
"IPR037143",
"IPR026025",
"IPR050830",
"IPR041550",
"IPR014030",
"IPR004568",
"IPR014031",
"IPR013968"
] | {"IPR036291": [492, 729], "IPR016039": [794, 1515], "IPR037143": [1547, 1665], "IPR026025": [10, 1666], "IPR050830": [25, 1493], "IPR040899": [74, 232], "IPR009081": [75, 153], "IPR041550": [259, 456], "IPR013968": [494, 569], "IPR020841": [833, 1428], "IPR047224": [994, 1425], "IPR014030": [1002, 1198], "IPR014031": [... | - Fatty acid synthase beta subunit aflB
- Acyl transferase domain protein
- Malonyl-CoA:ACP transacylase (MAT) domain-containing protein
- Acyl transferase domain protein
- Acetyl-CoA carboxylase central region
- Fatty acid synthase subunit alpha
- Ketosynthase family 3 (KS3) domain-containing protein
- Beta-ketoacyl s... | - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [492-729]
- IPR040899: Fatty acid synthase subunit alpha, acyl carrier domain (domain) [74-232]
- IPR008278: 4'-phosphopantetheinyl transferase domain (domain) [1549-1642]
- IPR020841: Polyketide synthase, beta-ketoacyl synthase domain (domain) [83... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0004312 (fatty acid synthase activity)
Biological Process (BP):... |
Q8TGA1 | Fatty acid synthase beta subunit aflB | Fatty acid synthase beta subunit; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide- derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxi... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 1,888 | null | MGSVSREHESIPIQAAQRGAARICAAFGGQGSNNLDVLKGLLELYKRYGPDLDELLDVASNTLSQLASSPAAIDVHEPWGFDLRQWLTTPEVAPSKEILALPPRSFPLNTLLSLALYCATCRELELDPGQFRSLLHSSTGHSQGILAAVAITQAESWPTFYDACRTVLQISFWIGLEAYLFTPSSAASDAMIQDCIEHGEGLLSSMLSVSGLSRSQVERVIEHVNKGLGECNRWVHLALVNSHEKFVLAGPPQSLWAVCLHVRRIRADNDLDQSRILFRNRKPIVDILFLPISAPFHTPYLDGVQDRVIEALSSASLALH... | [
"GO:0005575",
"GO:0005835",
"GO:0032991",
"GO:0140535",
"GO:1902494",
"GO:1990234"
] | [] | [] | [
"GO:0005575",
"GO:0005835",
"GO:0032991",
"GO:0140535",
"GO:1902494",
"GO:1990234"
] | AF-Q8TGA1-F1-model_v6.pdb | 1403190.Q8TGA1 | [
"A0A0F0IN54",
"Q8TGA2",
"A0A0F0I3U8",
"A0A0F0ILF1",
"A0A0F0IGH1",
"A0A0F0HZD0",
"A0A0F0I2A0",
"A0A0F0III1",
"A0A0F0ILA6",
"A0A0F0IHY3",
"A0A0F0IK72",
"A0A0F0I494",
"A0A0F0HZA4"
] | [
"IPR001227",
"IPR013565",
"IPR029069",
"IPR039569",
"IPR040883",
"IPR016452",
"IPR003965",
"IPR050830",
"IPR002539",
"IPR013785",
"IPR014043",
"IPR032088",
"IPR016035"
] | {"IPR001227": [10, 1706], "IPR016035": [23, 1862], "IPR013785": [412, 695], "IPR029069": [1166, 1510], "IPR016452": [4, 1887], "IPR050830": [16, 1887], "IPR032088": [27, 257], "IPR003965": [434, 1704], "IPR013565": [581, 922], "IPR040883": [977, 1118], "IPR039569": [1134, 1255], "IPR002539": [1399, 1500], "IPR014043": ... | - Fatty acid synthase subunit alpha
- Fatty acid synthase alpha subunit aflA
- Fatty acid synthase subunit alpha
- Ketosynthase family 3 (KS3) domain-containing protein
- Beta-ketoacyl synthase C-terminal domain protein
- Acetyl-CoA carboxylase central region
- Acyl transferase domain protein
- Malonyl-CoA:ACP transacy... | - IPR001227: Acyl transferase domain superfamily (homologous_superfamily) [10-1706]
- IPR013565: Fatty acid synthase beta subunit AflB /Fas1-like, central domain (domain) [581-922]
- IPR029069: HotDog domain superfamily (homologous_superfamily) [1166-1510]
- IPR039569: FAS1-like, dehydratase domain region (domain) [113... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016491 (oxidoreductase activity), GO:0016746 (acyltransferase activity), GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors), GO:0016747 (acyltransferase activity, tran... |
Q00278 | Norsolorinic acid ketoreductase | Norsolorinic acid ketoreductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide- derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 271 | Cytoplasm, cytosol. Vacuole | MNGSLSQHDQERLSTPYRDGPPEETVYLVTGASRGIGRGLIEAFLQRPKSTVVAWLRNVRTATPALSALTVAEGSRMIIVQLNSDSETDAQAAVQTLREEHGVTHLDVVVANAAMATNFGPASTMPLEHLQAHMMVNMYAPVLLFQATRLMLQQSKQQAKFVLIGAPISTITNMHDYSRAPLTAYGVSKLAANYMVRKFHFENKWLTAFIIDPGHVQTDMGDQGARLMGRPQAPTTVADSVAGICARIDEATKETTSGHFVIHTDGSQLPW | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005773",
"GO:0005775",
"GO:0031974",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005773",
"GO:0005775",
"GO:0031974",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | AF-Q00278-F1-model_v6.pdb | 1403190.Q00278 | null | [
"IPR036291",
"IPR051468",
"IPR002347"
] | {"IPR036291": [26, 271], "IPR002347": [26, 247], "IPR051468": [27, 271]} | - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [26-271]
- IPR051468: Fungal Secondary Metabolite SDRs (family) [27-271]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [26-247] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (B... | |
Q12732 | Averantin hydroxylase | Averantin hydroxylase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2),... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 495 | Membrane; Single-pass membrane protein | MGGDGWPSDGHILLLIVLTVLTPPSLALYRLWIHPLRSYPGPRWWAIWRGPYILSNIRGNLVRDLQRLHQQFGPVVRIAPNELSFIVPEAASPIYTSNPEFPKDPMHLPPFHNGTPGILAADHAHHRRYRRLLAFSFSDKGLRHERSLIERSIDLLITQLHENCGQGPLDLALWFNWATFDIIGDLAFGDSFGCLENVQTHPWIASIQGNVKLIPILNAFRRYRLDGLLRLLGSRKLLEQRRRNAQFTTDQVDRRLKNSSTPRGDIWDAVLAQKPDGEPPMTRDEMISNASAIVLAGSETSATLLSGCTWLLLKNPSHLH... | [
"GO:0003674",
"GO:0003824",
"GO:0016491",
"GO:0016705",
"GO:0140395"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016491",
"GO:0016705",
"GO:0140395"
] | [] | AF-Q12732-F1-model_v6.pdb | 1403190.Q12732 | [
"A0A0F0IM89",
"P87017"
] | [
"IPR050121",
"IPR017972",
"IPR001128",
"IPR002401",
"IPR036396"
] | {"IPR036396": [29, 495], "IPR050121": [13, 466], "IPR001128": [40, 469], "IPR002401": [69, 459], "IPR017972": [429, 438]} | - Short chain dehydrogenase
- 5'-hydroxyaverantin dehydrogenase | - IPR050121: Cytochrome P450 monooxygenase (family) [13-466]
- IPR017972: Cytochrome P450, conserved site (conserved_site) [429-438]
- IPR001128: Cytochrome P450 (family) [40-469]
- IPR002401: Cytochrome P450, E-class, group I (family) [69-459]
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [29-495] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process),... |
P87017 | 5'-hydroxyaverantin dehydrogenase | 5'-hydroxyaverantin dehydrogenase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide- derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatox... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 278 | Cytoplasm, cytosol | MEVLDTTVDLGTLQGKSALITGGASGIGLATARAWAAAGMYVTIADIQPLETGQNILADLAGGHVHYVCCDVTSWESQITAFKEAIQFTPSKALDIVAAFAGVSFAGGNQVDHVLAAGDPRLDVNPSPPDIRNIQVNLIGVYYTSWLGLYYLRLSPTNKAANPSPDKSLILMGSIGSYMDSPKASTYPASKFGVRGLFRSTRARTRELGVRCNLLAPWFIDTPLIAPMKKAMAARGIDMAQRLTFASVDACVEAATTCAANPQLHGTPPIRYAYCLKT | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-P87017-F1-model_v6.pdb | 1403190.P87017 | [
"Q12062",
"Q12732"
] | [
"IPR036291",
"IPR020904",
"IPR002347"
] | {"IPR036291": [12, 265], "IPR002347": [16, 229], "IPR020904": [174, 202]} | - Versicolorin B synthase
- Averantin hydroxylase | - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [12-265]
- IPR020904: Short-chain dehydrogenase/reductase, conserved site (conserved_site) [174-202]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [16-229] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0042802 (identical protein binding), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0046983 (protein dimeriza... |
Q12437 | Averufin oxidase A | Averufin oxidase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), afla... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 285 | Membrane; Single-pass membrane protein | MVTYALLGATGATGSSILRHLLQKSPDSLHIQVLVRSKVKLLQAFPDLETTRRPQVHVIQGMSTDSDALSECLRNASIVFMCVAQNGSPIGTTLCQDSARPIISVLQQQQQSEGASYQPCTIVQLRSASLNPALAAQVPAFVHRIVSFCLFANYADIKQACQYYSEAQKQGTLEYILVDPPTLHDANGTHPTGYRLISTEPQATALSYADLGAAMCEIAHRESEFHGRAVGVTATGRVRQTWGVLLRHLLEGGSSRLRETIAKEAVVVRVLCIFLVILACLMSSL | [
"GO:0003674",
"GO:0003824",
"GO:0016491"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016491"
] | [] | AF-Q12437-F1-model_v6.pdb | 1403190.Q12437 | null | [
"IPR036291",
"IPR051606",
"IPR016040"
] | {"IPR036291": [3, 232], "IPR051606": [3, 234], "IPR016040": [8, 220]} | - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [3-232]
- IPR051606: Polyketide Oxidoreductase-like (family) [3-234]
- IPR016040: NAD(P)-binding domain (domain) [8-220] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process),... | |
Q9UW95 | Versicolorin B desaturase | Versicolorin B desaturase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2 (AF... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 500 | Membrane; Single-pass membrane protein | MYFLSLPSLVIVIPVGYLLFHLGYNLFFHPLRGYPGPLLWRASSLPWKIALLRGTMHHDLMRFHQKYGDTVRIKPDEISYANAQAWRDIHAHVPGRPEFLKDPVRLPLAPNGVMSILVSDTKNHARFRSLFGHAFSDKGLRTQESTIVQYADLLVEVLREVADTGRSAEMVYYFNMAIFDSIGALSFGESFDSLKSRQLHPWVDAIHKNLKSVAISHVLRSMGIEFLTPYVLPKELRGKRQENYSYAVEKLNKRMKMEGDQGDFWDKVLVKSADDNQRGDGMSAGEMLNNAAVMVVAGSETTASALSGAMYLLCLSGKIE... | [
"GO:0003674",
"GO:0003824",
"GO:0016491",
"GO:0016705",
"GO:0016717",
"GO:0140398"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016491",
"GO:0016705",
"GO:0016717",
"GO:0140398"
] | [] | AF-Q9UW95-F1-model_v6.pdb | 1403190.Q9UW95 | null | [
"IPR050121",
"IPR017972",
"IPR001128",
"IPR002401",
"IPR036396"
] | {"IPR036396": [24, 497], "IPR050121": [7, 465], "IPR001128": [38, 468], "IPR002401": [177, 461], "IPR017972": [431, 440]} | - IPR050121: Cytochrome P450 monooxygenase (family) [7-465]
- IPR017972: Cytochrome P450, conserved site (conserved_site) [431-440]
- IPR001128: Cytochrome P450 (family) [38-468]
- IPR002401: Cytochrome P450, E-class, group I (family) [177-461]
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [24-497] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabolic process), GO:0019748 (secondary metabolic p... | |
P50161 | Versicolorin reductase 1 | Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), aflatoxin B2... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 262 | Cytoplasm, cytosol | MSDNHRLDGKVALVTGAGRGIGAAIAVALGERGAKVVVNYAHSREAAEKVVEQIKANGTDAIAIQADVGDPEATAKLMAETVRHFGYLDIVSSNAGIVSFGHLKDVTPEEFDRVFRVNTRGQFFVAREAYRHMREGGRIILTSSNTACVKGVPKHAVYSGSKGAIDTFVRCMAIDCGDKKITVNAVAPGAIKTDMFLAVSREYIPNGETFTDEQVDECAAWLSPLNRVGLPVDVARVVSFLASDTAEWVSGKIIGVDGGAFR | [
"GO:0003674",
"GO:0003824",
"GO:0016491",
"GO:0016614",
"GO:0042469",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016491",
"GO:0016614",
"GO:0042469"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-P50161-F1-model_v6.pdb | 1403190.P50161 | [
"Q6UEF2"
] | [
"IPR036291",
"IPR020904",
"IPR002347",
"IPR057326"
] | {"IPR036291": [8, 260], "IPR002347": [11, 259], "IPR057326": [10, 194], "IPR020904": [145, 173]} | - Oxidoreductase aflX | - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [8-260]
- IPR020904: Short-chain dehydrogenase/reductase, conserved site (conserved_site) [145-173]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [11-259]
- IPR057326: Ketoreductase domain (domain) [10-194] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (B... |
Q12120 | Sterigmatocystin 8-O-methyltransferase | Sterigmatocystin 8-O-methyltransferase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), afl... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 418 | Cytoplasm. Vacuole | MALPSKAALVGLANTLSEQVKRYLATAGETKSPEDHKLCIESERTPSSNEHAQAWEIVRTCDRIGSLVHGPVPWLLSNALSHLDSACLAAATHLNLQDIIVDGPSPTSLDTIVAATGVSEDLLRRILRGCAQRFIFEEVAPDQYAHTDASKMLRVTGIHALVGFSCDEVMRSGASFSDFLQQTKGKPPSWNVPSPFSLAFDPTKGLFDYYSTVDEVRGRRFDLGMGGTEATKPLVEEMFDFSSLPEGSTVVDVGGGRGHLSRRVSQKHPHLRFIVQDLPAVIHGVEDTDKVTMMEHDIRRPNPVRGADVYLLRSILHDYP... | [
"GO:0003674",
"GO:0003824",
"GO:0008168",
"GO:0008171",
"GO:0016740",
"GO:0016741",
"GO:0047146",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0008168",
"GO:0008171",
"GO:0016740",
"GO:0016741",
"GO:0047146"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-Q12120-F1-model_v6.pdb | 1403190.Q12120 | [
"Q6UEG8",
"Q9UQY0",
"A0A0F0IBA6",
"A0A0F0IG46",
"O13345"
] | [
"IPR016461",
"IPR036388",
"IPR012967",
"IPR036390",
"IPR001077",
"IPR029063"
] | {"IPR036390": [65, 154], "IPR036388": [71, 153], "IPR029063": [158, 404], "IPR016461": [76, 415], "IPR012967": [80, 153], "IPR001077": [206, 387]} | - O-methylsterigmatocystin oxidoreductase
- Demethylsterigmatocystin 6-O-methyltransferase
- O-methyltransferase
- O-methyltransferase
- Aflatoxin biosynthesis regulatory protein | - IPR016461: O-methyltransferase-like (family) [76-415]
- IPR036388: Winged helix-like DNA-binding domain superfamily (homologous_superfamily) [71-153]
- IPR012967: O-methyltransferase, dimerisation domain (domain) [80-153]
- IPR036390: Winged helix DNA-binding domain superfamily (homologous_superfamily) [65-154]
- IPR... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008168 (methyltransferase activity), GO:0008171 (O-methyltransferase activity)
Biological Process (BP): GO:0008150 (biologi... |
O13345 | O-methylsterigmatocystin oxidoreductase | O-methylsterigmatocystin oxidoreductase; part of the gene cluster that mediates the biosynthesis of aflatoxins, a group of polyketide-derived furanocoumarins, and part of the most toxic and carcinogenic compounds among the known mycotoxins. The four major aflatoxins produced by A.parasiticus are aflatoxin B1 (AFB1), af... | Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) | 528 | null | MIYSIIICAGALLGFLILQKLLAPKDTRPPLPPGPWRKPIIGNLTDFPPKGTPEWLFWAKHHERYGPMSSLEVMGQTIIMINDAHLGIEIMHKKSALSQMIPDAPFAHMAGWGMSLATERNKQAWKTIRANMKQEIGTRRAIATFHPKMEIGIRRFLLRTLDNPDDLRFHIRKEANAFMMDVAYGYTIAPHGKDELYDLTQQSVRQFSHIFSPGEWSVNFFPILRYVPSWFPGASFQIKAAEYKRTIERMTMVPYLWIKDQVARGCTRPSILLRLLQKGHYESGSHQEQVLVWTNAEFVMGGSDTTVSAVSSFFVAMALY... | [
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0016491"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0016491"
] | [] | AF-O13345-F1-model_v6.pdb | 1403190.O13345 | [
"Q12120"
] | [
"IPR017972",
"IPR001128",
"IPR002401",
"IPR050364",
"IPR036396"
] | {"IPR036396": [23, 496], "IPR050364": [6, 507], "IPR001128": [32, 489], "IPR002401": [62, 463], "IPR017972": [433, 442]} | - Sterigmatocystin 8-O-methyltransferase | - IPR017972: Cytochrome P450, conserved site (conserved_site) [433-442]
- IPR001128: Cytochrome P450 (family) [32-489]
- IPR002401: Cytochrome P450, E-class, group I (family) [62-463]
- IPR050364: Cytochrome P450 monooxygenase, fungi (family) [6-507]
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [23... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0009058 (biosynthetic process),... |
Q59Z29 | Iron-regulated transcriptional activator AFT2 | Transcription factor involved in iron metabolism, oxidative stress, surface adhesion, hyphal development and virulence. Functions as a negative regulator of MRS4 expression through the CACCC AFT-type sequence in a gene dose-dependent fashion. Acts as a repressor in flocculation, plastic adhesion, and surface hydrophobi... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 798 | Nucleus | MTDRVTHRVSLDDLNLEKQKFDSKDDIKPWLQDNLQSTKGINVVIERSDTSKIIFKCKNKEKKTKIVESKKTASKTMIRKHTSCPFKIRANYSVRNKVWTLSIVSDEHDHVVDLPRSFVGKNLISNTIPGSSLNVLDSVAPRSNKKGIKPTSEIANTPSVTSYSPSCAVKRNEDVDAPKISSKKARNLTKKPSTQSTRSSSSSDGSSIVSFGSLTSQSSSTSLPENYKGQVPTSMDSMVVEESLTGKSLKPAASHPVKRKNMKANTMKKSKKLKQNPIVVSPIEEDSNLNSFDDANIDLQRQQSLQSPLSHLVQNQDPIS... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0006873",
"GO:0006879",
"GO:0006950",
"GO:0006979",
"GO:0007155",
"GO:0008150",
"GO:0009267",
"GO:0009607",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010570"... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0006873",
"GO:0006879",
"GO:0006950",
"GO:0006979",
"GO:0007155",
"GO:0008150",
"GO:0009267",
"GO:0009607",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010570"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q59Z29-F1-model_v6.pdb | 237561.Q59Z29 | [
"Q5AF81",
"Q59SS1"
] | [
"IPR014842"
] | {"IPR014842": [21, 111]} | - Monothiol glutaredoxin
- Ccc1p | - IPR014842: Iron-regulated transcriptional activator AFT (family) [21-111] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biolog... |
O67434 | Protein argonaute | A DNA-guided RNA endonuclease. Uses short ssDNA sequences as guides (gDNA) to bind complementary target strands, resulting in cleavage of the target RNA. The cleavage site is 10 nucleotides downstream of the residue base paired with the 5'-end of the gDNA. Binds ssDNA better than ssRNA, binds dsDNA and DNA- RNA hybrids... | Aquifex aeolicus (strain VF5) | 706 | null | MGKEALLNLYRIEYRPKDTTFTVFKPTHEIQKEKLNKVRWRVFLQTGLPTFRREDEFWCAGKVEKDTLYLTLSNGEIVELKRVGEEEFRGFQNERECQELFRDFLTKTKVKDKFISDFYKKFRDKITVQGKNRKIALIPEVNEKVLKSEEGYFLLHLDLKFRIQPFETLQTLLERNDFNPKRIRVKPIGIDFVGRVQDVFKAKEKGEEFFRLCMERSTHKSSKKAWEELLKNRELREKAFLVVLEKGYTYPATILKPVLTYENLEDEERNEVADIVRMEPGKRLNLIRYILRRYVKALRDYGWYISPEEERAKGKLNFKD... | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004521",
"GO:0004540",
"GO:0140098",
"GO:0140640"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004521",
"GO:0004540",
"GO:0140098",
"GO:0140640"
] | [] | AF-O67434-F1-model_v6.pdb | 224324.aq_1447 | [
"O67435",
"O67433"
] | [
"IPR003165",
"IPR012337",
"IPR003100",
"IPR036397",
"IPR036085"
] | {"IPR036085": [4, 314], "IPR012337": [334, 706], "IPR036397": [492, 705], "IPR003100": [168, 259], "IPR003165": [419, 694]} | - 8-OXO-dGTPase domain (MutT domain)
- Uncharacterized protein aq_1446 | - IPR003165: Piwi domain (domain) [419-694]
- IPR012337: Ribonuclease H-like superfamily (homologous_superfamily) [334-706]
- IPR003100: PAZ domain (domain) [168-259]
- IPR036397: Ribonuclease H superfamily (homologous_superfamily) [492-705]
- IPR036085: PAZ domain superfamily (homologous_superfamily) [4-314] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... |
A4WYU7 | Protein argonaute | A catalytically inactive argonaute protein. Binds 5'- phosphorylated RNA as the guide (gRNA) and short DNA as target DNA (tDNA); does not bind other nucleic acid combinations, does not bind tDNA alone. Has highest affinity for gRNA that begins with 5'-phospho-U and poor affinity for gRNA with 5'-OH. Upon expression in ... | Cereibacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) (Rhodobacter | 777 | null | MAPVQAADEMYDSNPHPDRRQLVSNGFEVNLPDQVEVIVRDLPDPSKVKEERTRLMGYWFVHWFDGKLFHLRIKAGGPNVDGEHRAIRTAEHPWLLRARLDDALEEALPKYAAVKKRPFTFLAQKDELIDAAATAAGLSHRLLNSFKVIPRFALSPKIYEPVDGTTRVGVFVTIGMRYDIEASLRDLLEAGIDLRGMYVVRRKRQPGERGLLGRVRAISDDMVQLFEETDLASVNVNDAKLEGSKENFTRCLSALLGHNYKKLLNALDDQEAGYRTGPRFDDAVRRMGEFLAKKPIRLADNINAQVGDRIVFSNEGQARN... | [
"GO:0006950",
"GO:0006952",
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0043207",
"GO:0044355",
"GO:0044419",
"GO:0050896",
"GO:0051707",
"GO:0098542",
"GO:0099046",
"GO:0140546",
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0140097"... | [
"GO:0006950",
"GO:0006952",
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0043207",
"GO:0044355",
"GO:0044419",
"GO:0050896",
"GO:0051707",
"GO:0098542",
"GO:0099046",
"GO:0140546"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0140097",
"GO:0140640"
] | [] | AF-A4WYU7-F1-model_v6.pdb | null | null | [
"IPR003165",
"IPR036397",
"IPR012337"
] | {"IPR012337": [321, 777], "IPR036397": [516, 777], "IPR003165": [445, 757]} | - IPR003165: Piwi domain (domain) [445-757]
- IPR036397: Ribonuclease H superfamily (homologous_superfamily) [516-777]
- IPR012337: Ribonuclease H-like superfamily (homologous_superfamily) [321-777] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... | |
A0A1M5A5Z8 | Protein argonaute | A highly versatile argonaute that uses 5'-phospho- and 5'- OH- guide RNA (gRNA) or DNA (gDNA) to cleave target RNA or ssDNA (tDNA) in all possible combinations; has no detectable activity in the absence of guide. Uses short guide sequences (18-21 nucleotides (nt) on average) to bind complementary target nucleic acids r... | Marinitoga hydrogenitolerans (strain DSM 16785 / JCM 12826 / AT1271) | 640 | null | MYLNLYEIKIPYRVKRLYYFNKENDPKEFARNLSRVNNIRFNDSKDLVWLEIPDIDFKITPQQAEKYKIEKNEIIGEKEDSDLFVKTIYRYIKKKFIDNNFYYKRGNNYISINDKFPLDSNTNVNAHLTYKIKLYKINERYYISVLPKFTFLSDKPALESPIKSTYLFNIKSGKTFPYISGLNGVLKIDLGENGIKEVLFPENYYFNFTSKEAEKFGFSKEIHNIYKEKIFSGYKKIKQSLYFLEDIININNYNLTMDKKIYVNIEYEFKKGISRNIKDVFKYSFYKNDQKIKIAFFFSSKKQIYEIQRSLKMLFQNKNS... | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004521",
"GO:0004536",
"GO:0004540",
"GO:0140097",
"GO:0140098",
"GO:0140640"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004521",
"GO:0004536",
"GO:0004540",
"GO:0140097",
"GO:0140098",
"GO:0140640"
] | [] | AF-A0A1M5A5Z8-F1-model_v6.pdb | 1122195.SAMN02745164_02104 | [
"A0A1M5A5N0",
"A0A1M5A679",
"A0A1M5A5P1"
] | [
"IPR054434",
"IPR054387",
"IPR003165",
"IPR012337",
"IPR036397"
] | {"IPR012337": [410, 626], "IPR036397": [433, 604], "IPR054387": [13, 75], "IPR054434": [262, 430], "IPR003165": [369, 633]} | - CRISPR-associated endonuclease Cas1
- TOTE conflict system primase domain-containing protein
- CRISPR-associated endoribonuclease Cas2 | - IPR054434: Argonaute, middle domain, bacteria (domain) [262-430]
- IPR054387: Argonaute, N-terminal domain, bacteria (domain) [13-75]
- IPR003165: Piwi domain (domain) [369-633]
- IPR012337: Ribonuclease H-like superfamily (homologous_superfamily) [410-626]
- IPR036397: Ribonuclease H superfamily (homologous_superfam... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... |
H2J4R4 | Protein argonaute | An RNA-guided ssDNA endonuclease that may play a role in defense against invading mobile genetic elements. Uses short 5'-OH- ssRNA sequences as guides (gRNA) to bind complementary target DNA (tDNA) or target RNA resulting in target cleavage. The cleavage site is 10 nucleotides (nt) downstream of the target residue base... | Marinitoga piezophila (strain DSM 14283 / JCM 11233 / KA3) | 639 | Cytoplasm | MYLNLYKIDIPKKIKRLYFYNPDMEPKLFARNLSRVNNFKFQDSNDLVWIEIPDIDFQITPKNVFQYKVEKEEIIKEEEDKKLFVKTLYKYIKKLFLDNDFYFKKGNNFISNSEVFSLDSNENVNAHLTYKIKIHNISNEYYLSILPKFTFLSKEPALESAIKSGYLYNIKSGKSFPYISGLDGILKIDIGNNQIVEVAYPENYLFNFTTRDAEKYGFSKEVHEIYKNKVFEGFKKIPKTLGFLNKITNLNENYQLKDGYKIFINVIYKFKNGESRYAKDVFKYSFYKNEQPLKAIFFFSSKKQFFEVQKSLKELFHNKH... | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0140097",
"GO:0140640"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0140097",
"GO:0140640"
] | [] | AF-H2J4R4-F1-model_v6.pdb | 443254.Marpi_0405 | [
"H2J4R1",
"H2J4R2",
"H2J4R3"
] | [
"IPR054434",
"IPR054387",
"IPR003165",
"IPR012337",
"IPR036397"
] | {"IPR012337": [415, 627], "IPR036397": [436, 634], "IPR054387": [12, 76], "IPR054434": [263, 432], "IPR003165": [394, 634]} | - CRISPR-associated endonuclease Cas1
- CRISPR-associated endoribonuclease Cas2
- TOTE conflict system primase domain-containing protein | - IPR054434: Argonaute, middle domain, bacteria (domain) [263-432]
- IPR054387: Argonaute, N-terminal domain, bacteria (domain) [12-76]
- IPR003165: Piwi domain (domain) [394-634]
- IPR012337: Ribonuclease H-like superfamily (homologous_superfamily) [415-627]
- IPR036397: Ribonuclease H superfamily (homologous_superfam... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... |
Q58717 | Protein argonaute | A DNA-guided ssDNA endonuclease that may play a role in defense against invading genetic elements. Uses short ssDNA sequences as guides (gDNA) to bind complementary target strands, resulting in slicing of the target DNA (tDNA). Endonucleolytically cleaves tDNA (the gDNA indicates where to cleave); two major and two min... | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM | 713 | null | MVLNKVTYKINAYKIKEEFIPKEVHFYRIKSFVNEAFNFYRFVNFYGGMIINKKDKSFVLPYKVDNKVLKYKDGNNEIPIDIEYIKSLKLEYVKPEIAEKLVRGYLKSVHKIEPELSRIIKNIRKHKVVENIKVESYCEYEVKKHDGDYYLILNFRHTASITKHLWDFVNRDKALLEEYVGKKIIFKPNPKVRYTISLVDAPNPQKIEEIMSHIIKYYKWSEDMVKSTFGEIDYNQPIMYCEEILEPFAPQFCNLVFYMDELDSYILKELQSYWRLSNENKGKIINEIAKKLRFIDNTPKELEFMKFNNTPLLVKDVNKN... | [
"GO:0006950",
"GO:0006952",
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0043207",
"GO:0044355",
"GO:0044419",
"GO:0050896",
"GO:0051707",
"GO:0098542",
"GO:0099046",
"GO:0140546",
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0140097"... | [
"GO:0006950",
"GO:0006952",
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0043207",
"GO:0044355",
"GO:0044419",
"GO:0050896",
"GO:0051707",
"GO:0098542",
"GO:0099046",
"GO:0140546"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0140097",
"GO:0140640"
] | [] | AF-Q58717-F1-model_v6.pdb | 243232.MJ_1321 | [
"Q58907",
"Q58719",
"Q58716",
"Q57841",
"Q58718"
] | [
"IPR003100",
"IPR054390",
"IPR012337",
"IPR003165",
"IPR054436",
"IPR036085",
"IPR036397"
] | {"IPR036085": [5, 305], "IPR012337": [301, 713], "IPR036397": [494, 713], "IPR054390": [22, 90], "IPR054436": [163, 258], "IPR003100": [164, 257], "IPR003165": [426, 699]} | - Uncharacterized protein MJ0398
- Reverse gyrase
- DNA double-strand break repair protein Mre11
- DNA double-strand break repair Rad50 ATPase
- Ribonuclease VapC4 | - IPR003100: PAZ domain (domain) [164-257]
- IPR054390: Argonaute, N-terminal domain, archaea (domain) [22-90]
- IPR012337: Ribonuclease H-like superfamily (homologous_superfamily) [301-713]
- IPR003165: Piwi domain (domain) [426-699]
- IPR054436: Argonaute, PAZ domain, methanocaldococcus (domain) [163-258]
- IPR036085... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... |
Q8U3D2 | Protein argonaute | A DNA-guided ssDNA endonuclease that may play a role in defense against invading mobile genetic elements. Uses short 5'- phospho-ssDNA sequences as guides (gDNA) to bind complementary target strands, resulting in cleavage of the target DNA (tDNA). Endonucleolytically cleaves DNA in short dsDNA (the gDNA indicates where... | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) | 770 | null | MKAKVVINLVKINKKIIPDKIYVYRLFNDPEEELQKEGYSIYRLAYENVGIVIDPENLIIATTKELEYEGEFIPEGEISFSELRNDYQSKLVLRLLKENGIGEYELSKLLRKFRKPKTFGDYKVIPSVEMSVIKHDEDFYLVIHIIHQIQSMKTLWELVNKDPKELEEFLMTHKENLMLKDIASPLKTVYKPCFEEYTKKPKLDHNQEIVKYWYNYHIERYWNTPEAKLEFYRKFGQVDLKQPAILAKFASKIKKNKNYKIYLLPQLVVPTYNAEQLESDVAKEILEYTKLMPEERKELLENILAEVDSDIIDKSLSEIE... | [
"GO:0006950",
"GO:0006952",
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0043207",
"GO:0044355",
"GO:0044419",
"GO:0050896",
"GO:0051707",
"GO:0098542",
"GO:0099046",
"GO:0140546",
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0005488"... | [
"GO:0006950",
"GO:0006952",
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0043207",
"GO:0044355",
"GO:0044419",
"GO:0050896",
"GO:0051707",
"GO:0098542",
"GO:0099046",
"GO:0140546"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0005488",
"GO:0030145",
"GO:0036094",
"GO:0043167",
"GO:0043169",
"GO:0046872",
"GO:0046914",
"GO:0140097",
"GO:0140640"
] | [] | AF-Q8U3D2-F1-model_v6.pdb | 186497.PF0537 | null | [
"IPR003100",
"IPR012337",
"IPR057272",
"IPR003165",
"IPR021103",
"IPR036085",
"IPR036397",
"IPR055253"
] | {"IPR036085": [4, 323], "IPR012337": [325, 770], "IPR036397": [547, 770], "IPR055253": [19, 78], "IPR021103": [146, 272], "IPR003100": [154, 272], "IPR057272": [333, 753], "IPR003165": [473, 756]} | - IPR003100: PAZ domain (domain) [154-272]
- IPR012337: Ribonuclease H-like superfamily (homologous_superfamily) [325-770]
- IPR057272: Piwi domain, nematodes (domain) [333-753]
- IPR003165: Piwi domain (domain) [473-756]
- IPR021103: Argonaute PAZ domain, archaea (domain) [146-272]
- IPR036085: PAZ domain superfamily ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... | |
Q31N05 | Protein argonaute | A DNA-guided ssDNA endonuclease that might play a role in defense against invading mobile genetic elements. Uses short ssDNA sequences as guides (gDNA) to bind complementary target strands, resulting in cleavage of the target DNA (tDNA). The cleavage site is 10 nucleotides (nt) downstream of the target residue base-pai... | Synechococcus elongatus (strain ATCC 33912 / PCC 7942 / FACHB-805) | 735 | null | MDLLSNLRRSSIVLNRFYVKSLSQSDLTAYEYRCIFKKTPELGDEKRLLASICYKLGAIAVRIGSNIITKEAVRPEKLQGHDWQLVQMGTKQLDCRNDAHRCALETFERKFLERDLSASSQTEVRKAAEGGLIWWVVGAKGIEKSGNGWEVHRGRRIDVSLDAEGNLYLEIDIHHRFYTPWTVHQWLEQYPEIPLSYVRNNYLDERHGFINWQYGRFTQERPQDILLDCLGMSLAEYHLNKGATEEEVQQSYVVYVKPISWRKGKLTAHLSRRLSPSLTMEMLAKVAEDSTVCDREKREIRAVFKSIKQSINQRLQEAQK... | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0140097",
"GO:0140640"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0140097",
"GO:0140640"
] | [] | AF-Q31N05-F1-model_v6.pdb | 1140.Synpcc7942_1534 | null | [
"IPR040895",
"IPR003165",
"IPR036397",
"IPR012337"
] | {"IPR012337": [307, 732], "IPR036397": [507, 735], "IPR040895": [185, 276], "IPR003165": [441, 720]} | - IPR040895: Argonaute, PAZ domain (domain) [185-276]
- IPR003165: Piwi domain (domain) [441-720]
- IPR036397: Ribonuclease H superfamily (homologous_superfamily) [507-735]
- IPR012337: Ribonuclease H-like superfamily (homologous_superfamily) [307-732] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... | |
Q746M7 | Protein argonaute | A DNA-guided ssDNA endonuclease. Uses short ssDNA sequences as guides (gDNA, also called small interfering DNA, siDNA) to bind complementary DNA target strands, resulting in cleavage of the target DNA (tDNA). The cleavage site is 10 nucleotides (nt) downstream of the target residue base-paired with the 5'-end of the gD... | Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) | 685 | null | MNHLGKTEVFLNRFALRPLNPEELRPWRLEVVLDPPPGREEVYPLLAQVARRAGGVTVRMGDGLASWSPPEVLVLEGTLARMGQTYAYRLYPKGRRPLDPKDPGERSVLSALARRLLQERLRRLEGVWVEGLAVYRREHARGPGWRVLGGAVLDLWVSDSGAFLLEVDPAYRILCEMSLEAWLAQGHPLPKRVRNAYDRRTWELLRLGEEDPKELPLPGGLSLLDYHASKGRLQGREGGRVAWVADPKDPRKPIPHLTGLLVPVLTLEDLHEEEGSLALSLPWEERRRRTREIASWIGRRLGLGTPEAVRAQAYRLSIPK... | [
"GO:0006950",
"GO:0006952",
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0043207",
"GO:0044355",
"GO:0044419",
"GO:0050896",
"GO:0051707",
"GO:0098542",
"GO:0099046",
"GO:0140546",
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0005488"... | [
"GO:0006950",
"GO:0006952",
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0043207",
"GO:0044355",
"GO:0044419",
"GO:0050896",
"GO:0051707",
"GO:0098542",
"GO:0099046",
"GO:0140546"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0005488",
"GO:0030145",
"GO:0036094",
"GO:0043167",
"GO:0043169",
"GO:0046872",
"GO:0046914",
"GO:0140097",
"GO:0140640"
] | [] | AF-Q746M7-F1-model_v6.pdb | null | null | [
"IPR040895",
"IPR012337",
"IPR003165",
"IPR054764",
"IPR054763",
"IPR003100",
"IPR036397"
] | {"IPR012337": [282, 685], "IPR036397": [467, 685], "IPR054764": [26, 96], "IPR003100": [169, 265], "IPR040895": [181, 263], "IPR054763": [327, 444], "IPR003165": [404, 671]} | - IPR040895: Argonaute, PAZ domain (domain) [181-263]
- IPR012337: Ribonuclease H-like superfamily (homologous_superfamily) [282-685]
- IPR003165: Piwi domain (domain) [404-671]
- IPR054764: Argonaute, N-terminal domain, thermus (domain) [26-96]
- IPR054763: Argonaute, middle domain (domain) [327-444]
- IPR003100: PAZ ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0016032 (viral process), GO:0009058 (biosynthetic process), GO:0044237 (cellular metabo... | |
Q8R4S7 | Aryl hydrocarbon receptor | Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer. Upon ligand binding, translocates into the nucleus, where it heterodimerizes ... | Mus caroli (Ryukyu mouse) (Ricefield mouse) | 854 | Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus | MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQDLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDSAQGVDEAHGPPQTAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPSGCDAKGQLILGYTEVELCTRGSGY... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613",
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226"... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613"
] | [
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q8R4S7-F1-model_v6.pdb | null | null | [
"IPR036638",
"IPR035965",
"IPR033348",
"IPR013767",
"IPR011598",
"IPR000014",
"IPR013655",
"IPR001610",
"IPR039091"
] | {"IPR036638": [30, 80], "IPR035965": [120, 386], "IPR039091": [6, 811], "IPR011598": [26, 87], "IPR033348": [27, 87], "IPR000014": [111, 384], "IPR013767": [112, 185], "IPR013655": [298, 380], "IPR001610": [346, 387]} | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [30-80]
- IPR035965: PAS domain superfamily (homologous_superfamily) [120-386]
- IPR033348: Aryl hydrocarbon receptor, basic helix-loop-helix domain (domain) [27-87]
- IPR013767: PAS fold (domain) [112-185]
- IPR011598: Myc-type, basi... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:... | |
Q8R4S6 | Aryl hydrocarbon receptor | Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer. Upon ligand binding, translocates into the nucleus, where it heterodimerizes ... | Mus musculus castaneus (Southeastern Asian house mouse) | 848 | Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus | MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQDLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPDSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGYQFIH... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613",
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226"... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613"
] | [
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q8R4S6-F1-model_v6.pdb | null | null | [
"IPR036638",
"IPR035965",
"IPR033348",
"IPR013767",
"IPR011598",
"IPR000014",
"IPR013655",
"IPR001610",
"IPR039091"
] | {"IPR036638": [30, 80], "IPR035965": [120, 382], "IPR039091": [6, 791], "IPR011598": [26, 87], "IPR033348": [27, 87], "IPR000014": [111, 380], "IPR013767": [112, 177], "IPR013655": [293, 376], "IPR001610": [342, 383]} | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [30-80]
- IPR035965: PAS domain superfamily (homologous_superfamily) [120-382]
- IPR033348: Aryl hydrocarbon receptor, basic helix-loop-helix domain (domain) [27-87]
- IPR013767: PAS fold (domain) [112-177]
- IPR011598: Myc-type, basi... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:... | |
Q8R4S5 | Aryl hydrocarbon receptor | Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer. Upon ligand binding, translocates into the nucleus, where it heterodimerizes ... | Mus musculus molossinus (Japanese house mouse) | 883 | Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus | MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQDLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPDSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGYQFIH... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613",
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226"... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613"
] | [
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q8R4S5-F1-model_v6.pdb | null | null | [
"IPR036638",
"IPR035965",
"IPR033348",
"IPR013767",
"IPR011598",
"IPR000014",
"IPR013655",
"IPR001610",
"IPR039091"
] | {"IPR036638": [30, 80], "IPR035965": [120, 382], "IPR039091": [6, 791], "IPR011598": [26, 87], "IPR033348": [27, 87], "IPR000014": [111, 380], "IPR013767": [112, 177], "IPR013655": [293, 376], "IPR001610": [342, 383]} | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [30-80]
- IPR035965: PAS domain superfamily (homologous_superfamily) [120-382]
- IPR033348: Aryl hydrocarbon receptor, basic helix-loop-helix domain (domain) [27-87]
- IPR013767: PAS fold (domain) [112-177]
- IPR011598: Myc-type, basi... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:... | |
Q8R4S4 | Aryl hydrocarbon receptor | Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer. Upon ligand binding, translocates into the nucleus, where it heterodimerizes ... | Mus spicilegus (Steppe mouse) | 854 | Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus | MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQDLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGY... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613",
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226"... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613"
] | [
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q8R4S4-F1-model_v6.pdb | null | null | [
"IPR036638",
"IPR035965",
"IPR033348",
"IPR013767",
"IPR011598",
"IPR000014",
"IPR013655",
"IPR001610",
"IPR039091"
] | {"IPR036638": [30, 80], "IPR035965": [120, 386], "IPR039091": [6, 803], "IPR011598": [26, 87], "IPR033348": [27, 87], "IPR000014": [111, 384], "IPR013767": [112, 184], "IPR013655": [297, 380], "IPR001610": [346, 387]} | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [30-80]
- IPR035965: PAS domain superfamily (homologous_superfamily) [120-386]
- IPR033348: Aryl hydrocarbon receptor, basic helix-loop-helix domain (domain) [27-87]
- IPR013767: PAS fold (domain) [112-184]
- IPR011598: Myc-type, basi... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:... | |
Q8R4S2 | Aryl hydrocarbon receptor | Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer. Upon ligand binding, translocates into the nucleus, where it heterodimerizes ... | Mus spretus (Western Mediterranean mouse) (Algerian mouse) | 854 | Cytoplasm. Nucleus. Note=Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus | MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQNLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDSAQGVDEAHGPPQAAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPIGCDAKGQLILGYTEVELCTRGSGY... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613",
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226"... | [
"GO:0008150",
"GO:0009987",
"GO:0042221",
"GO:0050896",
"GO:0051716",
"GO:0070887",
"GO:1904612",
"GO:1904613"
] | [
"GO:0000981",
"GO:0003674",
"GO:0003700",
"GO:0004879",
"GO:0038023",
"GO:0060089",
"GO:0098531",
"GO:0140110"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q8R4S2-F1-model_v6.pdb | null | null | [
"IPR036638",
"IPR035965",
"IPR033348",
"IPR013767",
"IPR011598",
"IPR000014",
"IPR013655",
"IPR001610",
"IPR039091"
] | {"IPR036638": [30, 80], "IPR035965": [120, 386], "IPR039091": [6, 806], "IPR011598": [26, 87], "IPR033348": [27, 87], "IPR000014": [109, 384], "IPR013767": [112, 184], "IPR013655": [297, 380], "IPR001610": [346, 387]} | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [30-80]
- IPR035965: PAS domain superfamily (homologous_superfamily) [120-386]
- IPR033348: Aryl hydrocarbon receptor, basic helix-loop-helix domain (domain) [27-87]
- IPR013767: PAS fold (domain) [112-184]
- IPR011598: Myc-type, basi... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:... | |
Q09701 | Palmitoyltransferase akr1 | Palmitoyltransferase specific for casein kinase 1 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | 642 | Early endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein | MGSLFLAASQGELDTVKNLISSEKIDVNATDEGGATALHWAALNQQIPICKFLLEHGADVNAIGGDLQAAPIHWAAKRGSVKTVHYLVQHGADPLLKDKQGFNCLHLAVHAASPLLVVYLLHLDISVDLRDDQQHTPLMWASYHGNEPITNCLLRWGADVLATDEDKMTPLHWSIVGGNLKCMKLILKEGGIPCTAVTANLSGQLKTPWALASELRVSHLFKQALISNGLKVKETSEEPEKWVVVPSKFQFSQKTFIIFCFLSSFIITGVFFFIMSICPMVISLIIAPLWIYFTFKYITTCIHANIDIVHFYLETPFLAG... | [
"GO:0003674",
"GO:0003824",
"GO:0016409",
"GO:0016417",
"GO:0016740",
"GO:0016746",
"GO:0016747",
"GO:0019706",
"GO:0019707",
"GO:0140096"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016409",
"GO:0016417",
"GO:0016740",
"GO:0016746",
"GO:0016747",
"GO:0019706",
"GO:0019707",
"GO:0140096"
] | [] | AF-Q09701-F1-model_v6.pdb | 284812.Q09701 | [
"O43028",
"O60069"
] | [
"IPR036770",
"IPR002110",
"IPR001594"
] | {"IPR036770": [1, 224], "IPR001594": [396, 532], "IPR002110": [1, 196]} | - Vacuolar protein 8
- Palmitoyltransferase swf1 | - IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [1-224]
- IPR002110: Ankyrin repeat (repeat) [1-196]
- IPR001594: Palmitoyltransferase, DHHC domain (domain) [396-532] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016409 (pa... |
Q6UXT8 | ALK and LTK ligand 1 | Cytokine that acts as a physiological ligand for receptor tyrosine kinase LTK, leading to its activation. Monomeric ALKAL1 binds to LTK, leading to LTK homodimerization and activation. In contrast to ALKAL2, does not act as a potent physiological ligand for ALK | Homo sapiens (Human) | 129 | Secreted. Cell membrane. Note=Following interaction with receptor tyrosine kinase LTK, associates with the cell membrane, membrane-binding is required to activate LTK | MRPLKPGAPLPALFLLALALSPHGAHGRPRGRRGARVTDKEPKPLLFLPAAGAGRTPSGSRSAEIFPRDSNLKDKFIKHFTGPVTFSPECSKHFHRLYYNTRECSTPAYYKRCARLLTRLAVSPLCSQT | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0110165"
] | AF-Q6UXT8-F1-model_v6.pdb | 9606.ENSP00000351345 | [
"P29376"
] | [
"IPR029364"
] | {"IPR029364": [21, 129]} | - Leukocyte tyrosine kinase receptor | - IPR029364: ALK and LTK ligand 1/2 (family) [21-129] | Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0030545 (signaling receptor regulator activity), GO:0005515 (protein binding), GO:0005102 (si... |
Q8BS35 | Alkylglycerol monooxygenase | Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes (By similarity) | Mus musculus (Mouse) | 447 | Endoplasmic reticulum membrane; Multi-pass membrane protein | MRSPGAQDNVSVSQGMRAMFYMMEPSETAFQTVEEVPDYVKKATPFFIFLILLELVISWILKGKPSGRLDDALTSISAGVVSRLPSLFFRSLEVTSYIYIWENYRLLELPWDSTWTWYFTFLGVDFGYYWFHRMAHEINIFWAAHQAHHSSEDYNLSTALRQSVLQQYSSWVFYCPLALFIPPSVFAVHIQFNLLYQFWIHTEIIRTLGPLEVILNTPSHHRVHHGRNRYCIDKNYAGTLIIWDRIFGTFEAENEQVIYGLTHPIGTFEPFNVQFHHLLYIWTTFWTTPGFCHKFSVLFKGPGWGPGKPRLGLSEEIPEV... | [
"GO:0006629",
"GO:0006638",
"GO:0006639",
"GO:0006641",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0019432",
"GO:0044238",
"GO:0045017",
"GO:0046460",
"GO:0046463",
"GO:0046486",
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0016491",
"GO:0016705"... | [
"GO:0006629",
"GO:0006638",
"GO:0006639",
"GO:0006641",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0019432",
"GO:0044238",
"GO:0045017",
"GO:0046460",
"GO:0046463",
"GO:0046486"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0016491",
"GO:0016705",
"GO:0016714",
"GO:0050479"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031984",
"GO:0042175",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0098827",
"GO:0110165"
] | AF-Q8BS35-F1-model_v6.pdb | 10090.ENSMUSP00000051441 | null | [
"IPR056853",
"IPR006694",
"IPR051689"
] | {"IPR051689": [7, 445], "IPR006694": [118, 249], "IPR056853": [335, 422]} | - IPR056853: Alkylglycerol monooxygenase, C-terminal (domain) [335-422]
- IPR006694: Fatty acid hydroxylase (domain) [118-249]
- IPR051689: Sterol desaturase/TMEM195-like (family) [7-445] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0016714 (oxidoreductase activity, a... | |
P0A6B4 | Alanine racemase, biosynthetic | Catalyzes the interconversion of L-alanine and D-alanine. Provides the D-alanine required for cell wall biosynthesis | Escherichia coli (strain K12) | 359 | null | MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNEEQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHFARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVSPLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGD... | [
"GO:0006082",
"GO:0006520",
"GO:0006522",
"GO:0006523",
"GO:0008150",
"GO:0008152",
"GO:0008652",
"GO:0009058",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0030632",
"GO:0043436",
"GO:0044238",
"GO:0044281",
"GO:0044283",
"GO:0046394",
"GO:0046416",
"GO:0046436",
"GO:0046437"... | [
"GO:0006082",
"GO:0006520",
"GO:0006522",
"GO:0006523",
"GO:0008150",
"GO:0008152",
"GO:0008652",
"GO:0009058",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0030632",
"GO:0043436",
"GO:0044238",
"GO:0044281",
"GO:0044283",
"GO:0046394",
"GO:0046416",
"GO:0046436",
"GO:0046437"... | [
"GO:0003674",
"GO:0003824",
"GO:0005488",
"GO:0005515",
"GO:0008784",
"GO:0016853",
"GO:0016854",
"GO:0016855",
"GO:0019842",
"GO:0030170",
"GO:0036094",
"GO:0042802",
"GO:0042803",
"GO:0043167",
"GO:0043168",
"GO:0046983",
"GO:0047661",
"GO:0070279",
"GO:1901363"
] | [] | AF-P0A6B4-F1-model_v6.pdb | 511145.b4053 | [
"Q2M6Q2",
"Q2M8R2",
"Q2M923",
"P77636",
"P78246",
"P17952",
"P29011",
"P07862",
"P77727",
"Q2MC44",
"P14900",
"P22188"
] | [
"IPR000821",
"IPR011079",
"IPR009006",
"IPR029066",
"IPR020622",
"IPR001608"
] | {"IPR029066": [8, 235], "IPR009006": [215, 359], "IPR000821": [1, 359], "IPR001608": [8, 219], "IPR011079": [234, 358], "IPR020622": [31, 41]} | - D-alanine--D-alanine ligase B
- D-alanine--D-alanine ligase A
- UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
- Alanine racemase, catabolic
- D-amino acid dehydrogenase
- D-amino acid dehydrogenase
- D-amino acid dehydrogenase
- Glutamate-pyruvate aminotransferase AlaA
- Glutamate-pyruvate aminotransfera... | - IPR000821: Alanine racemase (family) [1-359]
- IPR011079: Alanine racemase, C-terminal (domain) [234-358]
- IPR009006: Alanine racemase/group IV decarboxylase, C-terminal (homologous_superfamily) [215-359]
- IPR029066: PLP-binding barrel (homologous_superfamily) [8-235]
- IPR020622: Alanine racemase, pyridoxal-phosph... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016853 (isomerase activity), GO:0016854 (racemase and epimerase activity), GO:0016855 (racemase and epimerase activity, acting on amino acids and derivatives), GO:0036361 (racemase activity, acting on amino acids and derivati... |
Q59L12 | Agglutinin-like protein 3 | Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the biofilm formation and pathogenesis of C.albicans infections. Necessary for C.albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent ... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,155 | Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Covers the surface of the germ tube | MLQQYTLLLIYLSVATAKTITGVFNSFNSLTWSNAATYNYKGPGTPTWNAVLGWSLDGTSASPGDTFTLNMPCVFKFTTSQTSVDLTAHGVKYATCQFQAGEEFMTFSTLTCTVSNTLTPSIKALGTVTLPLAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGGKKISINVDFERSNVDPKGYLTDSRVIPSLNKVSTLFVAPQCANGYTSGTMGFANTYGDVQIDCSNIHVGITKGLNDWNYPVSSESFSYTKTCSSNGIFITYKNVPAGYRPFVDAYISATDVNSYTLSYANEYTCAGGYWQRAPFTLRWTGYRNSDA... | [
"GO:0000041",
"GO:0006810",
"GO:0006811",
"GO:0006812",
"GO:0006826",
"GO:0006873",
"GO:0006878",
"GO:0006879",
"GO:0006897",
"GO:0007155",
"GO:0008150",
"GO:0009595",
"GO:0009602",
"GO:0009603",
"GO:0009605",
"GO:0009607",
"GO:0009608",
"GO:0009610",
"GO:0009620",
"GO:0009987"... | [
"GO:0000041",
"GO:0006810",
"GO:0006811",
"GO:0006812",
"GO:0006826",
"GO:0006873",
"GO:0006878",
"GO:0006879",
"GO:0006897",
"GO:0007155",
"GO:0008150",
"GO:0009595",
"GO:0009602",
"GO:0009603",
"GO:0009605",
"GO:0009607",
"GO:0009608",
"GO:0009610",
"GO:0009620",
"GO:0009987"... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0030984",
"GO:0030985",
"GO:0050839"
] | [
"GO:0005575",
"GO:0005576",
"GO:0005618",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0030445",
"GO:0030446",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043230",
"GO:0065010",
"GO:0071944",
"GO:0110165",
"GO:1903561"
] | AF-Q59L12-F1-model_v6.pdb | 237561.Q59L12 | [
"Q59NP5",
"Q59Y31",
"Q5A0E5",
"G1UBC2",
"Q5A8N2",
"Q5ANJ4",
"Q5AD07",
"Q59ME1",
"G1UB67",
"Q59U34",
"Q59TP1",
"Q59PF9",
"Q5ABE2",
"Q59PG4",
"Q9HFZ1",
"Q5A8I8",
"Q5ABW5",
"Q59XB5",
"Q5ACC9",
"Q59TL7",
"Q59XU5",
"Q59WZ4",
"Q5ALC8",
"Q5AB65"
] | [
"IPR008966",
"IPR043063",
"IPR008440",
"IPR033504",
"IPR024672",
"IPR011252"
] | {"IPR011252": [17, 177], "IPR008966": [24, 174], "IPR043063": [178, 329], "IPR033504": [1, 693], "IPR024672": [53, 298], "IPR008440": [365, 863]} | - Extent of cell elongation protein 1
- Hyphal wall protein 1
- Hyphally regulated cell wall protein 1
- Cell wall protein RBT1
- Enhanced filamentous growth protein 1
- Biofilm and cell wall regulator 1
- Transcriptional regulatory protein UME6
- Secreted aspartic protease 4
- Secreted aspartic protease 5
- Cell wall ... | - IPR008966: Adhesion domain superfamily (homologous_superfamily) [24-174]
- IPR043063: Agglutinin-like protein, N-terminal, N2 subdomain (homologous_superfamily) [178-329]
- IPR008440: Agglutinin-like protein repeat (repeat) [365-863]
- IPR033504: Agglutinin-like protein (family) [1-693]
- IPR024672: Agglutinin-like p... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0033218 (amide binding), GO:0050840 (extracellular matrix binding), GO:0005515 (protein binding), GO:0042277 (peptide binding), GO:0001968 (fibronectin binding), GO:0043236 (laminin binding)
Biological Process (BP): GO:0008150 (biologica... |
Q5A8T7 | Agglutinin-like protein 5 | Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections. Forms amyloid structures, essential for cell-cell association and cell-substrate adhesion to polystyrene | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,347 | Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer | MIQQFTLLFLYLSFATAKAITGIFNSIDSLTWSNAGNYAFKGPGYPTWNAVLGWSLDGTSANPGDTFILNMPCVFKFTASQKSVDLTADGVKYATCQFYSGEEFTTFSSLKCTVNNNLRSSIKALGTVTLPIAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGSKKLSIAVNFEKSTVDQSGYLTTSRFMPSLNKIATLYVAPQCENGYTSGTMGFSTSYGDVAIDCSNVHIGISKGVNDWNHPVTSESFSYTKSCSSFGISITYQNVPAGYRPFIDAYISPSDNNQYQLSYKNDYTCVDDYWQHAPFTLKWTGYKNSDA... | [
"GO:0007155",
"GO:0007160",
"GO:0008150",
"GO:0009987",
"GO:0031589",
"GO:0042710",
"GO:0043708",
"GO:0043709",
"GO:0043710",
"GO:0044010",
"GO:0044399",
"GO:0044403",
"GO:0044406",
"GO:0044409",
"GO:0044419",
"GO:0051701",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098609"... | [
"GO:0007155",
"GO:0007160",
"GO:0008150",
"GO:0009987",
"GO:0031589",
"GO:0042710",
"GO:0043708",
"GO:0043709",
"GO:0043710",
"GO:0044010",
"GO:0044399",
"GO:0044403",
"GO:0044406",
"GO:0044409",
"GO:0044419",
"GO:0051701",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098609"... | [
"GO:0001968",
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0042277"
] | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | AF-Q5A8T7-F1-model_v6.pdb | 237561.Q5A8T7 | null | [
"IPR008966",
"IPR043063",
"IPR008440",
"IPR033504",
"IPR024672",
"IPR011252"
] | {"IPR011252": [17, 177], "IPR008966": [25, 174], "IPR043063": [178, 329], "IPR033504": [1, 535], "IPR024672": [53, 298], "IPR008440": [365, 577]} | - IPR008966: Adhesion domain superfamily (homologous_superfamily) [25-174]
- IPR043063: Agglutinin-like protein, N-terminal, N2 subdomain (homologous_superfamily) [178-329]
- IPR008440: Agglutinin-like protein repeat (repeat) [365-577]
- IPR033504: Agglutinin-like protein (family) [1-535]
- IPR024672: Agglutinin-like p... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0033218 (amide binding), GO:0050840 (extracellular matrix binding), GO:0005515 (protein binding), GO:0042277 (peptide binding), GO:0001968 (fibronectin binding), GO:0043236 (laminin binding)
Biological Process (BP): GO:0008150 (biologica... | |
Q5A312 | Agglutinin-like protein 7 | Cell surface adhesion protein which mediates both yeast-to- host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,568 | Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Identified as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer | MKKLYLLYLLASFTTVISKEVTGVFNQFNSLIWSYTYRARYEEISTLTAKAQLEWALDGTIASPGDTFTLVMPCVYKFMTYETSVQLTANSIAYATCDFDAGEDTKSFSSLKCTVTDELTEDTSVFGSVILPIAFNVGGSGSKSTITDSKCFSSGYNTVTFFDGNNQLSTTANFLPRRELAFGLVVSQRLSMSLDTMTNFVMSTPCFMGYQSGKLGFTSNDDDFEIDCSSIHVGITNEINDWSMPVSSVPFDHTIRCTSRALYIEFKTIPAGYRPFVDAIVQIPTTEPFFVKYTNEFACVNGIYTSIPFTSFFSQPILYD... | [
"GO:0007155",
"GO:0008150",
"GO:0009987",
"GO:0031589",
"GO:0042710",
"GO:0043708",
"GO:0043709",
"GO:0043710",
"GO:0044010",
"GO:0044399",
"GO:0044403",
"GO:0044419",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743"
] | [
"GO:0007155",
"GO:0008150",
"GO:0009987",
"GO:0031589",
"GO:0042710",
"GO:0043708",
"GO:0043709",
"GO:0043710",
"GO:0044010",
"GO:0044399",
"GO:0044403",
"GO:0044419",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743"
] | [] | [] | AF-Q5A312-F1-model_v6.pdb | 237561.Q5A312 | null | [
"IPR008966",
"IPR043063",
"IPR008440",
"IPR033504",
"IPR024672",
"IPR011252"
] | {"IPR011252": [18, 176], "IPR008966": [49, 174], "IPR043063": [182, 326], "IPR033504": [3, 523], "IPR024672": [54, 299], "IPR008440": [403, 543]} | - IPR008966: Adhesion domain superfamily (homologous_superfamily) [49-174]
- IPR043063: Agglutinin-like protein, N-terminal, N2 subdomain (homologous_superfamily) [182-326]
- IPR008440: Agglutinin-like protein repeat (repeat) [403-543]
- IPR033504: Agglutinin-like protein (family) [3-523]
- IPR024672: Agglutinin-like p... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0033218 (amide binding), GO:0050840 (extracellular matrix binding), GO:0005515 (protein binding), GO:0042277 (peptide binding), GO:0001968 (fibronectin binding), GO:0043236 (laminin binding)
Biological Process (BP): GO:0008150 (biologica... | |
P15034 | Xaa-Pro aminopeptidase | null | Escherichia coli (strain K12) | 441 | Cytoplasm | MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVR... | [
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022607",
"GO:0043933",
"GO:0044085",
"GO:0051259",
"GO:0051260",
"GO:0051262",
"GO:0051289",
"GO:0065003",
"GO:0071840"
] | [
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022607",
"GO:0043933",
"GO:0044085",
"GO:0051259",
"GO:0051260",
"GO:0051262",
"GO:0051289",
"GO:0065003",
"GO:0071840"
] | [] | [] | AF-P15034-F1-model_v6.pdb | 511145.b2908 | [
"Q8XD28",
"P15288",
"Q2M9T4",
"P78048",
"Q2M649",
"P04825",
"Q2MBQ0",
"Q2M9T5"
] | [
"IPR001131",
"IPR052433",
"IPR001714",
"IPR029149",
"IPR007865",
"IPR036005",
"IPR000994"
] | {"IPR029149": [2, 177], "IPR036005": [175, 441], "IPR052433": [4, 435], "IPR001714": [256, 385], "IPR007865": [4, 139], "IPR000994": [185, 414], "IPR001131": [351, 363]} | - 2-octaprenyl-6-methoxyphenol hydroxylase
- Cytosol non-specific dipeptidase
- UPF0149 protein YgfB
- UPF0149 protein YgfB
- UPF0149 protein YgfB
- UPF0149 protein YgfB
- 2-octaprenylphenol hydroxylase
- Aminopeptidase N
- GMP reductase
- GMP reductase | - IPR001131: Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site (conserved_site) [351-363]
- IPR052433: Xaa-Pro dipeptidase-like (family) [4-435]
- IPR001714: Peptidase M24, methionine aminopeptidase (family) [256-385]
- IPR029149: Creatinase/Aminopeptidase P/Spt16, N-terminal (homologous_superfamily) [... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0043167 (ion binding), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0043169 (cation binding), GO... |
O74254 | Glucoamylase 1 | null | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 946 | Secreted, cell wall. Membrane; Peripheral membrane protein | MKLLSKVFVTALGLTSIVNAAPTSSSSAEEAQKTVPVELSIGVKQLPNIHNDSAVDANAVAKGYSLVNVSLTARGLTGILKLKEATNIYGYDFEYLNLSVEYQSDTRLNVHIEPTDLTDVFVLPEELVVKPKLEGDAKTFNFENSDLVFEYDEEDFGFEVLRSSTREVLFSTKGNPLVFSNQFIQFNTTLPKGHSITGLGESIHGSLNEPGVVKTLYANDIADPIDGNIYGVHPVYYDQRYNTNTTHAVYWRTSAIQEVVVGETSLTWRALSGVIDLYFFSGPDPKDVIQQYVSEIGLPAMQPYWALGYHQCRWGYDTVE... | [
"GO:0008150",
"GO:0009987",
"GO:0042710",
"GO:0044010",
"GO:0044011",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743",
"GO:0005575",
"GO:0005576",
"GO:0110165"
] | [
"GO:0008150",
"GO:0009987",
"GO:0042710",
"GO:0044010",
"GO:0044011",
"GO:0051703",
"GO:0090605",
"GO:0090609",
"GO:0098630",
"GO:0098743"
] | [] | [
"GO:0005575",
"GO:0005576",
"GO:0110165"
] | AF-O74254-F1-model_v6.pdb | 237561.O74254 | [
"Q59TZ8",
"A0A1D8PRS1",
"Q5A6V6",
"A0A1D8PJB5",
"A0A1D8PD78",
"A0A1D8PTY8",
"Q59RR7",
"Q5AJ73",
"A0A1D8PHV3",
"Q59RW5",
"A0A1D8PEW1",
"A0A1D8PUB9",
"Q9URL8",
"Q5AIA1",
"A0A1D8PP39",
"Q5AMT2"
] | [
"IPR030458",
"IPR017853",
"IPR030459",
"IPR000322",
"IPR048395",
"IPR013780",
"IPR011013"
] | {"IPR011013": [60, 285], "IPR017853": [286, 731], "IPR013780": [716, 946], "IPR000322": [299, 723], "IPR048395": [731, 821], "IPR030459": [655, 685], "IPR030458": [458, 465]} | - glucan 1,4-alpha-glucosidase
- Glucan 1,3-beta-glucosidase BGL2
- Glucoamylase 1
- Glucan 1,3-beta-glucosidase
- Hexokinase-2
- Alpha-glucosidase
- beta-glucosidase
- Glycosyl hydrolase family 13 catalytic domain-containing protein
- beta-glucosidase
- Phosphotransferase | - IPR030458: Glycosyl hydrolases family 31, active site (active_site) [458-465]
- IPR017853: Glycoside hydrolase superfamily (homologous_superfamily) [286-731]
- IPR030459: Glycosyl hydrolases family 31, conserved site (conserved_site) [655-685]
- IPR000322: Glycoside hydrolase family 31, TIM barrel domain (domain) [29... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015926 (glucosidase activity), GO:0090599 (alpha-glucosidase activ... |
Q59KZ1 | Aminopeptidase 2 | Metalloprotease that specifically hydrolyzes peptides with N- terminal alanine, arginine and leucine residues | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 924 | Secreted, cell wall | MASNNTSQRSGFSSFFCRLKTYFCNHFLCLFVLSFFPLSFRRLCLLCHLCEKSNLWLSSDNSASVVKQEREVLPTNVKPLHYDLTIEPIFDNFTFKGEETIDFQVNEKTNFITLNSLEIEVQEAKIDGKSVTDISFDAGKQTVTFKFDDDLSTGSIAKLYIKFTGELNDKMAGFYRASYQEDGKTKYMATTQMEPTDCRRAFPSYDEPAAKSKFTISLIADKELVCLSNSSEKETVSLDGNKKKVTFQTTPLMSTYLVAFIVGDLRYISNDNYRVPIRVYSTPGTEHLGEYSANIAAQTLKFFDQQFGIDYPYDKLDMVA... | [
"GO:0003674",
"GO:0003824",
"GO:0004177",
"GO:0008233",
"GO:0008235",
"GO:0008236",
"GO:0008237",
"GO:0008238",
"GO:0016787",
"GO:0017171",
"GO:0070006",
"GO:0140096",
"GO:0005575",
"GO:0005576",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004177",
"GO:0008233",
"GO:0008235",
"GO:0008236",
"GO:0008237",
"GO:0008238",
"GO:0016787",
"GO:0017171",
"GO:0070006",
"GO:0140096"
] | [
"GO:0005575",
"GO:0005576",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0071944",
"GO:0110165"
] | AF-Q59KZ1-F1-model_v6.pdb | 237561.Q59KZ1 | [
"Q5AI38"
] | [
"IPR034016",
"IPR050344",
"IPR027268",
"IPR045357",
"IPR024571",
"IPR001930",
"IPR014782",
"IPR042097"
] | {"IPR042097": [58, 264], "IPR027268": [268, 513], "IPR050344": [61, 918], "IPR034016": [80, 510], "IPR001930": [199, 391], "IPR045357": [78, 257], "IPR014782": [291, 508], "IPR024571": [582, 900]} | - 14-3-3 protein homolog | - IPR034016: Aminopeptidase N-type (family) [80-510]
- IPR050344: Peptidase M1 family aminopeptidases (family) [61-918]
- IPR027268: Peptidase M4/M1, CTD superfamily (homologous_superfamily) [268-513]
- IPR045357: Aminopeptidase N-like , N-terminal domain (domain) [78-257]
- IPR024571: ERAP1-like C-terminal domain (dom... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0008237 (metallopeptidase activity), GO:0008238 (exopeptidase activity), GO:0004177 (aminopeptidase activi... |
A0MTA1 | DNA repair nuclease APEX1 | Functions as an apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a ... | Danio rerio (Zebrafish) (Brachydanio rerio) | 310 | Nucleus. Nucleus, nucleolus. Nucleus speckle. Endoplasmic reticulum. Cytoplasm. Mitochondrion | MPKRAKKNEEGVDGEADNGTAAAKKEKKGKEPEAPILYEDPPEKLTSKDGRAANMKITSWNVDGLRAWVKKNGLDWVRKEDPDILCLQETKCAEKALPADITGMPEYPHKYWAGSEDKEGYSGVAMLCKTEPLNVTYGIGKEEHDKEGRVITAEFPDFFLVTAYVPNASRGLVRLDYRKTWDVDFRAYLCGLDARKPLVLCGDLNVAHQEIDLKNPKGNRKNAGFTPEEREGFTQLLEAGFTDSFRELYPDQAYAYTFWTYMMNARSKNVGWRLDYFVLSSALLPGLCDSKIRNTAMGSDHCPITLFLAV | [
"GO:0003674",
"GO:0003824",
"GO:0003906",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0140097",
"GO:0140640"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0003906",
"GO:0004518",
"GO:0004519",
"GO:0004520",
"GO:0004536",
"GO:0140097",
"GO:0140640"
] | [] | AF-A0MTA1-F1-model_v6.pdb | 7955.ENSDARP00000067373 | [
"F1QXI2",
"F8W5U2",
"B0R0V1",
"Q5RHR0",
"F1Q570",
"F1QMZ8",
"A2BIQ2",
"Q6GMM1",
"F1R6S6",
"B8JJK1",
"A0A0R4IHR6",
"Q6DRD3",
"B0R135",
"Q6NY87",
"Q7ZWH1",
"Q90440",
"F1QLV3",
"F1QK90",
"F1QBP9",
"A0A0R4ITV5",
"F1Q865",
"X1WBY3",
"F1R092",
"Q568J1",
"E7FBZ9",
"Q9PTP1"... | [
"IPR020848",
"IPR036691",
"IPR005135",
"IPR020847",
"IPR004808"
] | {"IPR036691": [30, 310], "IPR004808": [41, 310], "IPR005135": [59, 301], "IPR020848": [269, 280], "IPR020847": [82, 91]} | - Probable endonuclease 4 isoform X1
- Endonuclease III-like protein 1
- Flap endonuclease 1
- DNA polymerase beta
- N-glycosylase/DNA lyase
- DNA repair protein XRCC1
- Adenine DNA glycosylase
- Proliferating cell nuclear antigen
- DNA ligase
- Poly [ADP-ribose] polymerase 1 | - IPR020848: AP endonuclease 1, conserved site (conserved_site) [269-280]
- IPR036691: Endonuclease/exonuclease/phosphatase superfamily (homologous_superfamily) [30-310]
- IPR005135: Endonuclease/exonuclease/phosphatase (domain) [59-301]
- IPR020847: AP endonuclease 1, binding site (binding_site) [82-91]
- IPR004808: A... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0140097 (catalytic activity, acting on DNA), GO:0004518 (nuclease activity), G... |
Q59QC5 | Clathrin-associated protein AP-3 complex component APS3 | Part of the AP-3 complex, an adapter-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane (By similarity). Involved in vacuolar trafficking and contributes to hyphal growth ... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 175 | Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex | MIHSVLIFNNDGLPRLMKFYTKVDIPTQKLLLQQVHSLISTRSAQECSFITPPSLLEDLDDIKVIYRHYATLYFVFIVDDQESELGILDLIQVFVECLDKCFSNVCELDLVFGWQVLQTVLEEIVQGGMVIDTNINRIVAAVDEANSQKNVNSNGSTISASILSSLSRDRGFWGR | [
"GO:0006810",
"GO:0006892",
"GO:0006896",
"GO:0007034",
"GO:0008150",
"GO:0009987",
"GO:0016192",
"GO:0046907",
"GO:0048193",
"GO:0051179",
"GO:0051234",
"GO:0051641",
"GO:0051649"
] | [
"GO:0006810",
"GO:0006892",
"GO:0006896",
"GO:0007034",
"GO:0008150",
"GO:0009987",
"GO:0016192",
"GO:0046907",
"GO:0048193",
"GO:0051179",
"GO:0051234",
"GO:0051641",
"GO:0051649"
] | [] | [] | AF-Q59QC5-F1-model_v6.pdb | 237561.Q59QC5 | [
"Q5AJY4",
"A0A1D8PLU9",
"A0A1D8PF11",
"Q59RK0",
"A0A1D8PE70",
"A0A1D8PSB0",
"A0A1D8PJJ8",
"Q5ANA1"
] | [
"IPR000804",
"IPR022775",
"IPR016635",
"IPR011012"
] | {"IPR011012": [1, 143], "IPR016635": [1, 153], "IPR022775": [1, 147], "IPR000804": [64, 74]} | - AP-3 complex subunit delta
- Clathrin/coatomer adaptor adaptin-like N-terminal domain-containing protein
- AP-1 complex subunit gamma
- MHD domain-containing protein
- Large ribosomal subunit protein eL8A
- Large ribosomal subunit protein eL8B
- AP-2 complex subunit alpha
- Apm1p | - IPR000804: Clathrin adaptor complex, small chain (conserved_site) [64-74]
- IPR022775: AP complex, mu/sigma subunit (domain) [1-147]
- IPR016635: Adaptor protein complex, sigma subunit (family) [1-153]
- IPR011012: Longin-like domain superfamily (homologous_superfamily) [1-143] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0033036 (mac... |
Q6PGD0 | All-trans retinoic acid-induced differentiation factor | Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway (By similarity). In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) re... | Mus musculus (Mouse) | 223 | Nucleus envelope. Cell membrane; Single-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Note=Colocalizes with NELL1 on the nuclear envelope and the perinuclear region | MASRESGGSRAAALLLVLGVERALALPEICTLCPGGMHNLSRVAAYCEDTSKLMQARCCLNQKGTILGLDLQNCSLKDPGPNFLQAYTAIIIDLQANPLKDDLANTFRGFTQLQTLILPQDVPCPGGSNAWDNVTSFKDKQICQGQRDLCNSTGSPEMCPENGSCASDGPGLLQCVCADGFHGYKCMRQGSFSLLMFFGILGSTTLAISILLWGTQRRKAKAS | [
"GO:0006810",
"GO:0006855",
"GO:0008150",
"GO:0009987",
"GO:0042908",
"GO:0051179",
"GO:0051234",
"GO:0055085",
"GO:0003674",
"GO:0005215",
"GO:0005488",
"GO:0005515",
"GO:0022857",
"GO:0042910"
] | [
"GO:0006810",
"GO:0006855",
"GO:0008150",
"GO:0009987",
"GO:0042908",
"GO:0051179",
"GO:0051234",
"GO:0055085"
] | [
"GO:0003674",
"GO:0005215",
"GO:0005488",
"GO:0005515",
"GO:0022857",
"GO:0042910"
] | [] | AF-Q6PGD0-F1-model_v6.pdb | 10090.ENSMUSP00000013766 | null | [
"IPR000742",
"IPR042350"
] | {"IPR042350": [8, 222], "IPR000742": [146, 187]} | - IPR000742: EGF-like domain (domain) [146-187]
- IPR042350: All-trans retinoic acid-induced differentiation factor (family) [8-222] | Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (s... | |
P22274 | ADP-ribosylation factor | GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 179 | Golgi apparatus | MGLTISKLFASLLGRREMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRYYFQNTQGIIFVVDSNDRDRINEAREELQSMLNEDELKDAVLLVLANKQDLPNAMNAAEITEKMGLHSIRNRPWFIQATCATTGDGLYEGLEWLSNQVGK | [
"GO:0000302",
"GO:0006810",
"GO:0006886",
"GO:0006950",
"GO:0006979",
"GO:0008104",
"GO:0008150",
"GO:0009987",
"GO:0015031",
"GO:0033036",
"GO:0033554",
"GO:0034599",
"GO:0034614",
"GO:0042221",
"GO:0045184",
"GO:0046907",
"GO:0050896",
"GO:0051179",
"GO:0051234",
"GO:0051641"... | [
"GO:0000302",
"GO:0006810",
"GO:0006886",
"GO:0006950",
"GO:0006979",
"GO:0008104",
"GO:0008150",
"GO:0009987",
"GO:0015031",
"GO:0033036",
"GO:0033554",
"GO:0034599",
"GO:0034614",
"GO:0042221",
"GO:0045184",
"GO:0046907",
"GO:0050896",
"GO:0051179",
"GO:0051234",
"GO:0051641"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005794",
"GO:0012505",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-P22274-F1-model_v6.pdb | 237561.P22274 | [
"A0A1D8PMT6",
"A0A1D8PJI6",
"A0A1D8PTM6",
"Q5AHW5",
"Q5AMQ3",
"A0A1D8PCP6",
"A0A1D8PPS9",
"A0A1D8PJB0",
"Q96W97",
"Q5AJY4",
"A0A1D8PSB0",
"Q5A7M1",
"Q59KJ6",
"Q5ANF9",
"A0A1D8PND9",
"A0A1D8PPV5",
"A0A1D8PJ64",
"A0A1D8PTI2",
"Q5AMK5",
"A0A1D8PIG1",
"Q5AND9",
"Q9UW24",
"Q59... | [
"IPR027417",
"IPR006689",
"IPR024156",
"IPR005225",
"IPR045872"
] | {"IPR027417": [6, 179], "IPR024156": [1, 175], "IPR006689": [5, 177], "IPR045872": [18, 176], "IPR005225": [16, 160]} | - Fgr32p
- Arf family guanine nucleotide exchange factor
- Age3p
- Coatomer subunit gamma
- ADP-ribosylation factor GTPase-activating protein
- Arf3p
- Rga2p
- AP-1 complex subunit gamma
- Glycylpeptide N-tetradecanoyltransferase
- ADP-ribosylation factor | - IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [6-179]
- IPR006689: Small GTPase superfamily, ARF/SAR type (family) [5-177]
- IPR024156: Small GTPase superfamily, ARF type (family) [1-175]
- IPR005225: Small GTP-binding domain (domain) [16-160]
- IPR045872: ADP-ribosylation fa... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:1901265 (nucleoside phosphate binding)... |
P18335 | Acetylornithine/succinyldiaminopimelate aminotransferase | Involved in both the arginine and lysine biosynthetic pathways | Escherichia coli (strain K12) | 406 | Cytoplasm | MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDGFGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVD... | [
"GO:0006082",
"GO:0006520",
"GO:0006525",
"GO:0006526",
"GO:0006553",
"GO:0008150",
"GO:0008152",
"GO:0008652",
"GO:0009058",
"GO:0009064",
"GO:0009067",
"GO:0009084",
"GO:0009085",
"GO:0009089",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0033359",
"GO:0042450",
"GO:0043436"... | [
"GO:0006082",
"GO:0006520",
"GO:0006525",
"GO:0006526",
"GO:0006553",
"GO:0008150",
"GO:0008152",
"GO:0008652",
"GO:0009058",
"GO:0009064",
"GO:0009067",
"GO:0009084",
"GO:0009085",
"GO:0009089",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0033359",
"GO:0042450",
"GO:0043436"... | [] | [] | AF-P18335-F1-model_v6.pdb | 511145.b3359 | [
"Q2MBJ2",
"P0A9D8",
"Q2M8Q4",
"Q2MCE9",
"Q2MA19",
"Q2M8Q3",
"P76949",
"Q2M939",
"P24176",
"Q2M835",
"Q2M8Q2",
"Q2M744",
"Q2M655",
"Q47060",
"Q2MAP3"
] | [
"IPR015424",
"IPR004636",
"IPR050103",
"IPR015422",
"IPR015421",
"IPR005814",
"IPR049704",
"IPR017652"
] | {"IPR015424": [20, 401], "IPR015422": [30, 393], "IPR015421": [60, 305], "IPR017652": [8, 404], "IPR050103": [13, 403], "IPR004636": [16, 403], "IPR005814": [21, 402], "IPR049704": [223, 260]} | - N-acetyl-gamma-glutamyl-phosphate reductase
- Acetylglutamate kinase
- Amino-acid acetyltransferase
- Argininosuccinate lyase
- Acetylornithine deacetylase
- 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
- Succinyl-diaminopimelate desuccinylase
- Succinyl-diaminopimelate desuccinylase
- Argininos... | - IPR015424: Pyridoxal phosphate-dependent transferase (homologous_superfamily) [20-401]
- IPR004636: Acetylornithine/Succinylornithine transaminase family (family) [16-403]
- IPR050103: Class-III Pyridoxal-phosphate-dependent Aminotransferase (family) [13-403]
- IPR015422: Pyridoxal phosphate-dependent transferase, sm... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0016740 (transferase activity), GO:1901363 (heterocyclic compound binding), GO:0043168 (anion b... |
Q9VL63 | Arginine and glutamate-rich protein 1 | Post-transcriptional regulator of gene expression; modulates splicing and premature cleavage at cryptic polyadenylation sites of its own pre-mRNA through binding and regulation of the U1-snRNP complex | Drosophila melanogaster (Fruit fly) | 290 | Nucleus. Nucleus speckle. Note=Phase separation and localization to nuclear speckle-like structures is enhanced by binding to sisRNA | MGSRSRTPSPSGKRRHHKSKHKKRSKSHHDHERPSTRTDRDKSSEVNNHGRHRERDRDRERDRHRSDRHTERDYRHSPSILKSRKRSSSSSSDSQYSEQESQRSKQKRSRFKKLDEQNQMQVERLAEMERQRRAKELEQKTIEEEAAKRIEMLVKKRVEEELEKRRDEIEQEVNRRVETAKAEMEREMMLELERRREQIREEERRREEDEKQKREELEEILAENNRKIEEAQRKLAEERLAIIEEQRLMDEERQRMRKEQEKRVKEEQKVILGKNNSRPKLSFSLKPGAL | [
"GO:0003674",
"GO:0003676",
"GO:0003723",
"GO:0005488",
"GO:0036002",
"GO:0043021",
"GO:0044877",
"GO:0070990",
"GO:1990446",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0003676",
"GO:0003723",
"GO:0005488",
"GO:0036002",
"GO:0043021",
"GO:0044877",
"GO:0070990",
"GO:1990446"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q9VL63-F1-model_v6.pdb | 7227.FBpp0079491 | [
"Q9VM56",
"A0A0B4KF69",
"Q86B99"
] | [
"IPR033371"
] | {"IPR033371": [3, 286]} | - U1 small nuclear ribonucleoprotein 70 kDa
- Uncharacterized protein, isoform B
- non-specific serine/threonine protein kinase | - IPR033371: Arginine and glutamate-rich protein 1 (family) [3-286] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0022414 (reproductive process), GO:0032502 (developmental process),... |
Q5AME2 | Pentafunctional AROM polypeptide | The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,551 | Cytoplasm | MSIEKVPILGKETIHVGYGIADHIVREVIANLASSTYVIVTDTNMARTPQYSKLTDDFKTNLSEKRPESRLLTYCVSPGENNKNRATKAAVEDFLLQQGCTRDTVILAVGGGVIGDMIGFVAATFMRGVRVVQVPTTLLAMVDSSVGGKTAIDTPLGKNFIGAFHQPEYVFCDVSFLETLPARQFINGMAEVVKTAAIWNEEEFTRLENFSKKFLSVVTSKKPDLQSIKAELVKTVLESVRVKAGVVSSDEKEAGLRNLLNFGHTIGHAIEAVLTPEALHGECVSIGMIKEAELSRYLGILPPVAVARLSKCLVAYGLPV... | [
"GO:0006082",
"GO:0006520",
"GO:0006810",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009072",
"GO:0009073",
"GO:0009410",
"GO:0009987",
"GO:0015711",
"GO:0015801",
"GO:0015849",
"GO:0016053",
"GO:0019752",
"GO:0042221",
"GO:0043436",
"GO:0044238",
"GO:0044281",
"GO:0044283"... | [
"GO:0006082",
"GO:0006520",
"GO:0006810",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009072",
"GO:0009073",
"GO:0009410",
"GO:0009987",
"GO:0015711",
"GO:0015801",
"GO:0015849",
"GO:0016053",
"GO:0019752",
"GO:0042221",
"GO:0043436",
"GO:0044238",
"GO:0044281",
"GO:0044283"... | [] | [] | AF-Q5AME2-F1-model_v6.pdb | 237561.Q5AME2 | [
"A0A1D8PMB8",
"A0A1D8PFC8",
"A0A1D8PRN2",
"A0A1D8PGI8",
"A0A1D8PJH8",
"Q5A750",
"A0A1D8PMR2",
"Q5AMS9",
"A0A1D8PL79",
"Q5AMG5",
"Q9P940",
"A0A1D8PKY7",
"Q5APD8",
"A0A1D8PMB0",
"A0A1D8PG20",
"Q5A4M2",
"Q59TS4",
"Q5AB75",
"Q59LX7",
"A0A1D8PEG2",
"A0A1D8PMH6",
"Q5AMP2",
"Q5A... | [
"IPR006264",
"IPR013792",
"IPR010110",
"IPR008289",
"IPR001381",
"IPR016037",
"IPR036291",
"IPR036968",
"IPR041121",
"IPR013708",
"IPR023193",
"IPR000623",
"IPR056179",
"IPR027417",
"IPR031322",
"IPR013785",
"IPR046346",
"IPR030960",
"IPR006151",
"IPR001986"
] | {"IPR013792": [399, 834], "IPR036968": [405, 829], "IPR027417": [848, 1028], "IPR013785": [1029, 1267], "IPR046346": [1267, 1369], "IPR036291": [1370, 1549], "IPR008289": [1, 1551], "IPR016037": [13, 381], "IPR006264": [398, 838], "IPR000623": [858, 1025], "IPR031322": [867, 1019], "IPR001381": [1044, 1263], "IPR030960... | - Chorismate synthase
- Catabolic 3-dehydroquinase
- Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited
- Phospho-2-dehydro-3-deoxyheptonate aldolase
- Multifunctional tryptophan biosynthesis protein
- Tryptophan synthase
- Chorismate mutase
- Anthranilate phosphoribosyltransferase
- prephenate dehydratase... | - IPR006264: 3-phosphoshikimate 1-carboxyvinyltransferase (family) [398-838]
- IPR013792: RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta (homologous_superfamily) [399-834]
- IPR010110: Shikimate dehydrogenase, AroM-type (domain) [1269-1548]
- IPR008289: Pentafunctional AroM protein (family) [1-1... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016765 (transferase activity, transferring alkyl or aryl (other than methyl) groups)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cel... |
Q86WX3 | Active regulator of SIRT1 | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, m... | {ECO:0000303|PubMed:34516797}; | 136 | Nucleus, nucleolus | MSAALLRRGLELLAASEAPRDPPGQAKPRGAPVKRPRKTKAIQAQKLRNSAKGKVPKSALDEYRKRECRDHLRVNLKFLTRTRSTVAESVSQQILRQNRGRKACDRPVAKTKKKKAEGTVFTEEDFQKFQQEYFGS | [
"GO:0008150",
"GO:0009987",
"GO:0022613",
"GO:0042254",
"GO:0042274",
"GO:0044085",
"GO:0071840"
] | [
"GO:0008150",
"GO:0009987",
"GO:0022613",
"GO:0042254",
"GO:0042274",
"GO:0044085",
"GO:0071840"
] | [] | [] | AF-Q86WX3-F1-model_v6.pdb | 9606.ENSP00000333948 | [
"Q96A77",
"P0CW22",
"Q5BJI0",
"P55769",
"Q9Y3H5",
"Q9Y2P8",
"Q9BV24",
"Q9NT55",
"Q9NYH9",
"Q6IPY4",
"Q6IPH1",
"Q9NRX1",
"Q9BVZ0",
"Q96BN0",
"Q9NQ05",
"Q8IZ30",
"P62857",
"Q9NZX3",
"Q6IB08",
"Q9NQZ2",
"Q9BWK6",
"Q86XJ9",
"Q9NW23",
"Q9UPI6",
"Q9NWT8",
"Q86WX9",
"Q8N... | [
"IPR023262"
] | {"IPR023262": [1, 136]} | - NAD-dependent protein deacetylase sirtuin-1
- Small ribosomal subunit protein eS19
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein uS12
- WD repeat-containing protein 46
- Ribosomal RNA small subunit methyltransferase NEP1
- rRNA 2'-O-methyltransferase fibrillarin
- U3 small nucleolar ribonucl... | - IPR023262: Active regulator of SIRT1 (family) [1-136] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... |
Q5AC48 | Actin-related protein 4 | Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 com... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 468 | Nucleus | MATASTTTVYGGDEINAIVLDPGSYTTRIGYAGDDFPKVITSSYYGQVKNDKKKIFGESINVPRANYDIKPILKESIIVDWDAAIEQYQYYFDQQLKVVGPEQPILITEPIWTETSYRQQLVETFFENFEFSGIYLAKSPTCVSFQQGRSNCLVVDLGHDSVSVTPVIDGICLLKSSMKTNYGGKFLSNEIQDYLIDTKKVVMEPSFKIKSKIPTTYPDPPKYELKNNNTIPTSSSSSLSQSFLEFQNEKIYHNFKEILEVPEKNSSSGTTTTTTTTNKDSSRLFELPTGQSIVIDRFKIAESIFDPTIYKFTNSKLSFP... | [
"GO:0003674",
"GO:0003824",
"GO:0004402",
"GO:0008080",
"GO:0010485",
"GO:0016407",
"GO:0016410",
"GO:0016740",
"GO:0016746",
"GO:0016747",
"GO:0034212",
"GO:0061733",
"GO:0140096",
"GO:0140186",
"GO:0140993",
"GO:0000123",
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694"... | [] | [
"GO:0003674",
"GO:0003824",
"GO:0004402",
"GO:0008080",
"GO:0010485",
"GO:0016407",
"GO:0016410",
"GO:0016740",
"GO:0016746",
"GO:0016747",
"GO:0034212",
"GO:0061733",
"GO:0140096",
"GO:0140186",
"GO:0140993"
] | [
"GO:0000123",
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0031248",
"GO:0032991",
"GO:0035267",
"GO:0043189",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165",
"GO:0140535",
"GO:1902493",
"GO:1902494",
"GO:1902562",
"GO:1990234"
] | AF-Q5AC48-F1-model_v6.pdb | 237561.Q5AC48 | [
"A0A1D8PS09",
"A0A1D8PH73",
"Q5GM21",
"Q5ADM7",
"A0A1D8PG88",
"A0A1D8PKH5",
"A0A1D8PIP3",
"A0A1D8PGK4",
"Q5ADQ0",
"Q59QC2",
"A0A1D8PEB6",
"A0A1D8PPL1",
"A0A1D8PML5",
"A0A1D8PJ67",
"Q5A6Q7",
"Q5A190",
"Q59QT2",
"A0A1D8PIC9",
"Q5AAJ7",
"A0A1D8PG45",
"A0A1D8PJG4",
"Q59VN2",
... | [
"IPR004001",
"IPR043129",
"IPR004000"
] | {"IPR043129": [13, 465], "IPR004000": [12, 468], "IPR004001": [448, 456]} | - Actin
- Arp8p
- SWR1-complex protein 4
- Histone acetyltransferase
- Helicase SWR1
- Enhancer of polycomb-like protein 1
- RuvB-like helicase 1
- RuvB-like helicase 2
- Chromatin-remodeling ATPase INO80
- Snf5p | - IPR004001: Actin, conserved site (conserved_site) [448-456]
- IPR043129: ATPase, nucleotide binding domain (homologous_superfamily) [13-465]
- IPR004000: Actin family (family) [12-468] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0061733 (peptide-lysine-N-acetyltransferase activity), GO:0004402 (histone acetyltransferase activ... |
O43150 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 | Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration | Homo sapiens (Human) | 1,006 | Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Note=Colocalizes with F-actin and ARF6 in phagocytic cups | MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIR... | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-O43150-F1-model_v6.pdb | 9606.ENSP00000281419 | [
"Q6PID4",
"Q5HYA4",
"Q9NRJ5",
"Q9ULH1",
"P84085",
"Q6FGZ2",
"Q9NXK2",
"Q9NYR0"
] | [
"IPR036028",
"IPR011993",
"IPR001452",
"IPR037278",
"IPR038508",
"IPR001849",
"IPR002110",
"IPR036770",
"IPR043593",
"IPR037844",
"IPR001164",
"IPR027267",
"IPR004148",
"IPR035677"
] | {"IPR027267": [28, 328], "IPR011993": [300, 414], "IPR038508": [415, 547], "IPR037278": [420, 538], "IPR036770": [542, 693], "IPR036028": [929, 1004], "IPR043593": [1, 1006], "IPR004148": [33, 266], "IPR037844": [297, 403], "IPR001849": [305, 399], "IPR001164": [421, 543], "IPR001452": [944, 1006], "IPR035677": [948, 1... | - ADP-ribosylation factor 6
- Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3
- Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
- Protein-tyrosine kinase 2-beta
- Paxillin
- ADP-ribosylation factor 5
- Poly(A) polymerase beta
- SH3 domain-containing kinase-binding protein 1 | - IPR036028: SH3-like domain superfamily (homologous_superfamily) [929-1004]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [300-414]
- IPR001452: SH3 domain (domain) [944-1006]
- IPR037278: ARFGAP/RecO-like zinc finger (homologous_superfamily) [420-538]
- IPR038508: ArfGAP domain superfamily (homolog... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0016043 (cellular component organization), GO:0044085 (cell... |
Q59LV8 | Activator of stress genes protein 1 | Transcription factor necessary to sustain growth on non- fermentative carbon sources such as sodium acetate, acetic acid, or ethanol. Plays a role in hyphal formation | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 990 | Nucleus | MPKREIEDTQSPYSSTGLVSTGESPKTSTSTPTSSTNNRAATTTTNNTSTTSTSLLKSNSNLQPIAMTPSVSSTSLAINKPKSQENKRRRVTRACDTCRQKKVKCDGKQPCIHCTVYSYKCSYDQPNIRNKKNSGIPIPSQPSPAILQVAAQAAVAFGSNNNSSNQQSLQSLQQQQQHVVHQHQHQPLPADEPIPKTNLIIFQQIINALLPKLQLNGFDPNLQFDLNKFQKVVQYVMSKSQTFTLNLNEITELMQDPDSQIPPPPPASSSSSHHRRTLSVGSFDDSSNSAVSSPREVGLHLPSKEVALNLIYTTWNKACV... | [
"GO:0006355",
"GO:0006357",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010570",
"GO:0010604",
"GO:0019219",
"GO:0019222",
"GO:0030447",
"GO:0040007",
"GO:0040008",
"GO:0044182",
"GO:0045893",
"GO:0045944",
"GO:0048518"... | [
"GO:0006355",
"GO:0006357",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010570",
"GO:0010604",
"GO:0019219",
"GO:0019222",
"GO:0030447",
"GO:0040007",
"GO:0040008",
"GO:0044182",
"GO:0045893",
"GO:0045944",
"GO:0048518"... | [] | [] | AF-Q59LV8-F1-model_v6.pdb | 237561.Q59LV8 | [
"Q5APC5"
] | [
"IPR001138",
"IPR036864",
"IPR007219",
"IPR051711"
] | {"IPR036864": [84, 191], "IPR051711": [1, 892], "IPR001138": [89, 132], "IPR007219": [314, 583]} | - SURF1-like protein | - IPR001138: Zn(2)Cys(6) fungal-type DNA-binding domain (domain) [89-132]
- IPR036864: Zn(2)-C6 fungal-type DNA-binding domain superfamily (homologous_superfamily) [84-191]
- IPR007219: Xylanolytic transcriptional activator, regulatory domain (domain) [314-583]
- IPR051711: Stress Response Regulator (family) [1-892] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (... |
Q708S7 | Acid-sensing ion channel 1A | Forms voltage-independent, pH-gated trimeric sodium channels that act as postsynaptic excitatory receptors in the nervous system, playing a crucial role in regulating synaptic plasticity, learning, and memory. Upon extracellular pH drop this channel elicits transient, fast activating, and completely desensitizing inwar... | Danio rerio (Zebrafish) (Brachydanio rerio) | 501 | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Cell projection, dendrite | MKTSVMDLKVEPMDIDFDQPPPLQVFAHTSTLHGISHIFSYEKITAKCCLWVVFFLSSLTFLMYVCIDRIQFYLEYPHVTKLDEITTPVMVFPAVTICNLNSIRFSRITRNDLYHAGELLALLNSRHEVREAHLVEESVMEVLKSKTDFRSFKPRHFNMWEFYNRTGHDIKDMLLSCQFRGSPCRPEDFSVVFTRYGKCYTFNSGETGPPRVSVKGGMGNGLEIMLDIQQDEYLPVWGESDESSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQEQRLVYLPAPWGSCKSTPPSSDYFRAYSISACRTDCETRY... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q708S7-F1-model_v6.pdb | 7955.ENSDARP00000011782 | null | [
"IPR001873",
"IPR020903",
"IPR004724"
] | {"IPR001873": [24, 469], "IPR004724": [136, 480], "IPR020903": [307, 327]} | - IPR001873: Epithelial sodium channel (family) [24-469]
- IPR020903: Epithelial sodium channel, conserved site (conserved_site) [307-327]
- IPR004724: Epithelial sodium channel, chordates (family) [136-480] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:... | |
Q708S8 | Acid-sensing ion channel 1B | Forms voltage-independent, pH-gated trimeric sodium channels that act as postsynaptic excitatory receptors in the nervous system, playing a crucial role in regulating synaptic plasticity, learning, and memory. Upon extracellular pH drop this channel elicits transient, fast activating, and completely desensitizing inwar... | Danio rerio (Zebrafish) (Brachydanio rerio) | 557 | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Cell projection, dendrite | MVRITCTISFSTDDEPVGRSRQGSFDDHYKRVVWSKDGEQGKYQEEGDDPDAYDGPEDEEAPDISLATFFGGCSLHGANHVFVEDKKFSIRQGLWALVFLLAISMFLLQVVDRVIYYLQYDYVTLLDERNAKNMTFPAITLCNYNTFRRSQLSYSDLLFMGPLLGYEDNMAPGIPLAPEPDRQGSRFSLAEFFNRTRHRMDDMLLECNFAGKECGAEHWREIFTRYGKCYTFNSGQDGRPLLITTKGGMGNGLEIMLDIQQDEYLPVWGETDETTFEAGIKVQIHTQDEPPFIDQLGFGVAPGFQTFVSCQEQRLTYLPP... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q708S8-F1-model_v6.pdb | null | null | [
"IPR001873",
"IPR020903",
"IPR004724"
] | {"IPR001873": [67, 498], "IPR004724": [191, 514], "IPR020903": [338, 358]} | - IPR001873: Epithelial sodium channel (family) [67-498]
- IPR020903: Epithelial sodium channel, conserved site (conserved_site) [338-358]
- IPR004724: Epithelial sodium channel, chordates (family) [191-514] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:... | |
Q708S6 | Acid-sensing ion channel 1C | Forms voltage-independent, pH-gated trimeric sodium channels that act as postsynaptic excitatory receptors in the nervous system, playing a crucial role in regulating synaptic plasticity, learning, and memory. Upon extracellular pH drop this channel elicits transient, fast activating, and completely desensitizing inwar... | Danio rerio (Zebrafish) (Brachydanio rerio) | 529 | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Cell projection, dendrite | MTAMKGDSEDSIESMRPSNLQVFANNSTLHGMSHIFAYGHMTFRRFLWTLSFMGSLGLLMYVCMDRVYYYFEFPHVTKLDEVAAPNLTFPAVTFCNLNEFRFSKITKNDLYHVGELLALLNENYQIANPHLADPEVLTLLKEKASFNGFKPKQFNMTDFYNRTGHDINEMLLQCSFRGEECFPLNFTTIYTRYGKCYTFNSGLDGNPLLTTLKGGTGNGLEIMLDIQQDEYLPVWGDTDETSYEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVSCQQQLLLYLPPPWGDCRSAPMDSEYFSTYSITACRIDCETRYLL... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q708S6-F1-model_v6.pdb | 7955.ENSDARP00000130223 | [
"F1QZB9"
] | [
"IPR001873",
"IPR020903",
"IPR004724"
] | {"IPR001873": [20, 461], "IPR004724": [140, 475], "IPR020903": [305, 325]} | - Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 | - IPR001873: Epithelial sodium channel (family) [20-461]
- IPR020903: Epithelial sodium channel, conserved site (conserved_site) [305-325]
- IPR004724: Epithelial sodium channel, chordates (family) [140-475] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:... |
Q708S4 | Acid-sensing ion channel 4-A | Could form pH-gated trimeric sodium channels and function as a postsynaptic excitatory receptors in the nervous system | Danio rerio (Zebrafish) (Brachydanio rerio) | 539 | Cell membrane; Multi-pass membrane protein | MPIEFVCKIKFAEEDEKQKGNQDGDKESLIEESCSPPTKDLAGFASASSLHGINHIFVSGRLGVRQTLWALAFLVSLALFLYQAAKCAISYLEHPHVTALNEEATPEMVFPAVTICNINRFRFSALTDADIYHLANLTGLPPKNKDGHKPTDLEYPAPDMQDIFNRTGHQLEEMLKSCNFSGQNCSAEDFTVVYTRYGKCYTFNGNKTTSRKTKQGGMGNGLEIMLDIQQDDYLPIWKETNETSLEAGIRVQIHSQDEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRSTSEQMIPGYDTYSISACRLRCETL... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q708S4-F1-model_v6.pdb | 7955.ENSDARP00000035525 | null | [
"IPR001873",
"IPR020903"
] | {"IPR001873": [42, 465], "IPR020903": [308, 328]} | - IPR001873: Epithelial sodium channel (family) [42-465]
- IPR020903: Epithelial sodium channel, conserved site (conserved_site) [308-328] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:1901702 (salt transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:... | |
Q708S3 | Acid-sensing ion channel 4-B | Does not exhibit measurable stand-alone pH-gated sodium channel activity but may form pH-gated heterotrimeric sodium channels | Danio rerio (Zebrafish) (Brachydanio rerio) | 558 | Cell membrane; Multi-pass membrane protein | MPIEFVCKIKFAEGEEAKGASTEGGGTGMLDEGLRRQKEGMADLASFASSSSLHGLARALGTSERLGFRQTLWGLALLVSLGLFLYQATWSAATYLERPHLAALREETRRELTFPAITLCNVNRFRFSALTDADIYHLANLTGLPPKSRKGHRPSELQYPPPNMLDIFQRTGHQLEDMLKSCNFSGQNCSSEDFSVVYTRYGKCYTFNGNKTSPKRVRQGGTGNGLEMMLDIQQDEYLPIWRETNETTLEAGIRVQIHSQNEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPWGNCRASSEPVIPGYDTYSVSACRLH... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q708S3-F1-model_v6.pdb | 7955.ENSDARP00000095487 | [
"A3KPJ8"
] | [
"IPR001873",
"IPR020903"
] | {"IPR001873": [40, 467], "IPR020903": [312, 332]} | - IPR001873: Epithelial sodium channel (family) [40-467]
- IPR020903: Epithelial sodium channel, conserved site (conserved_site) [312-332] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0022803 (passive transmembrane transporter activity), GO:0005216 (monoatomic ion channel activity), GO:0015267 ... | |
Q5AMH1 | DASH complex subunit ASK1 | Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosom... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 594 | Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Nucleus | MKRYSIAPTSSRRKSAIDATLPESNLPARQILEQLDQDTTFVLQEIDKNISRANTVINDKIKPMIQEYAFQSWKVWENTGFWKHFFEQSANVELDSYVEPINEVNPQNNFLLLNEIEKNKQKGRYEDSRGSNKVNQANNDENNDIDNDEKEEPEIAFKKPNLRRLVADGNTPTWSTEHTKPSMKSIQLSPPKRMQTTNFTGGLARENTKLTDSITLEPPALSAETRAVTSSPHSRHYQNQHQRLQSRDSPIKIHTIRQSLDTYHRVSISPKKLKTPIRSTRTSRIESILNSSPILPEPPVLQSEIGSETPKYMSSSSPMK... | [
"GO:0008150",
"GO:0030447",
"GO:0040007"
] | [
"GO:0008150",
"GO:0030447",
"GO:0040007"
] | [] | [] | AF-Q5AMH1-F1-model_v6.pdb | 237561.Q5AMH1 | [
"A0A1D8PM85",
"A0A1D8PMD4",
"Q5A6Q0",
"Q59PZ2",
"Q59VC6",
"Q59ZG8",
"Q59P88",
"A0A1D8PFP9",
"Q5APC8",
"A0A1D8PTL5",
"Q59QH6"
] | [
"IPR013964"
] | {"IPR013964": [1, 569]} | - Tubulin gamma chain
- Spindle pole body component
- DASH complex subunit DAD3
- DASH complex subunit DAD2
- DASH complex subunit DAM1
- DASH complex subunit SPC34
- DASH complex subunit SPC19
- DASH complex subunit DAD1
- DASH complex subunit DUO1
- Actin-related protein 5 | - IPR013964: DASH complex subunit Ask1 (family) [1-569] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding), GO:0043565 (seque... |
A0A8I3NQW8 | PAT complex subunit Asterix | Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occ... | homolog; | 106 | Endoplasmic reticulum membrane; Multi-pass membrane protein | MSTNNMSDPRRPNKVLRYKPPPSECNPALDDPTPDYMNLLGMIFSMCGLMLKLKWCAWVAVYCSFISFANSRSSEDTKQMMSSFMLSISAVVMSYLQNPQPMTPPW | [
"GO:0006996",
"GO:0007029",
"GO:0008104",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0033036",
"GO:0033365",
"GO:0045048",
"GO:0045184",
"GO:0051179",
"GO:0051205",
"GO:0051234",
"GO:0051641",
"GO:0051668",
"GO:0061024",
"GO:0071840",
"GO:0090150",
"GO:0160063"... | [
"GO:0006996",
"GO:0007029",
"GO:0008104",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0033036",
"GO:0033365",
"GO:0045048",
"GO:0045184",
"GO:0051179",
"GO:0051205",
"GO:0051234",
"GO:0051641",
"GO:0051668",
"GO:0061024",
"GO:0071840",
"GO:0090150",
"GO:0160063"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0005829",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031984",
"GO:0032991",
"GO:0042175",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0072379",
"GO:0098827",
"GO:0110165",
"GO:0160064"... | AF-A0A8I3NQW8-F1-model_v6.pdb | null | null | [
"IPR005351"
] | {"IPR005351": [2, 106]} | - IPR005351: PAT complex subunit Asterix (family) [2-106] | Molecular Function (MF): GO:0003674 (molecular function), GO:0044183 (protein folding chaperone)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cellular compon... | |
Q5AAU5 | Cell wall acid trehalase ATC1 | Cell wall acid trehalase that catalyzes hydrolysis of the disaccharide trehalose and required for growth on trehalose as carbon source. Plays a role in dimorphic conversion and virulence | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,078 | Secreted, cell wall | MAANSSFFLADNCAPHNQSFIQFCIHAASKKKGRIALMCLANLFLLFSFHLLYARFCSGFPYVVPSTARSTNQIFHTNLEQLVNSPENKQIFSQLKFSDQAFYDPHDNVVGTTEFPVFNQYQRQPYVANGYIGSRIPNLGQGFTYDQLTNSSTANDDDLLNGWPLFNKRYSGAFVAGFYDLQKNTTGTNFAELLENGYESVIAAVPQWTALSLSVEILGKKYTLDPSLEHEAIGDITNYVQNMSLSDGIVTTQFTWLNTFDVKYEILAHRENINLGLVNMQVYNPGNESVQVIVSDVLDFNSSQRCQLNQISHDKNGIYV... | [
"GO:0005975",
"GO:0005984",
"GO:0005991",
"GO:0005993",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009311",
"GO:0009313",
"GO:0009987",
"GO:0016052",
"GO:0044238",
"GO:0046352",
"GO:0003674",
"GO:0003824",
"GO:0004553",
"GO:0004555",
"GO:0015927",
"GO:0016787",
"GO:0016798"... | [
"GO:0005975",
"GO:0005984",
"GO:0005991",
"GO:0005993",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009311",
"GO:0009313",
"GO:0009987",
"GO:0016052",
"GO:0044238",
"GO:0046352"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004553",
"GO:0004555",
"GO:0015927",
"GO:0016787",
"GO:0016798"
] | [
"GO:0005575",
"GO:0005576",
"GO:0005618",
"GO:0009277",
"GO:0030312",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043230",
"GO:0065010",
"GO:0071944",
"GO:0110165",
"GO:1903561"
] | AF-Q5AAU5-F1-model_v6.pdb | 237561.Q5AAU5 | [
"Q92410",
"A0A1D8PRR3"
] | [
"IPR037018",
"IPR005196",
"IPR012341",
"IPR008928",
"IPR005195",
"IPR011013"
] | {"IPR037018": [109, 379], "IPR011013": [166, 378], "IPR008928": [388, 844], "IPR012341": [437, 771], "IPR005196": [119, 379], "IPR005195": [442, 633]} | - Trehalase
- Alpha,alpha-trehalose-phosphate synthase [UDP-forming] | - IPR037018: Glycoside hydrolase family 65, N-terminal domain (homologous_superfamily) [109-379]
- IPR005196: Glycoside hydrolase, family 65, N-terminal (domain) [119-379]
- IPR012341: Six-hairpin glycosidase-like superfamily (homologous_superfamily) [437-771]
- IPR008928: Six-hairpin glycosidase superfamily (homologou... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O-glycosyl compounds), GO:0015927 (trehalase activity)
Biological Process (BP): GO:0008150 (b... |
Q86CR6 | Ubiquitin-like protein atg12 | Ubiquitin-like protein involved in autophagy vesicles formation. Required for atg8 association to the vesicle membranes. Conjugated to atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme is essential for its function (By similarity) | Dictyostelium discoideum (Social amoeba) | 124 | Cytoplasm | MEEEEKNNNEVASPTEQNTESTTEQQPQLPVKITSESKIIVYFKNAGGAQPLKQKKFKIQANVSFQNVIDKLRGQLKLKSNESLFLFINQVFQPSPDEILGELYKCFSHNDQLIINYSLQMAWG | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0032991",
"GO:0034274",
"GO:0110165",
"GO:1902494",
"GO:1990234"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0032991",
"GO:0034274",
"GO:0110165",
"GO:1902494",
"GO:1990234"
] | AF-Q86CR6-F1-model_v6.pdb | 44689.Q86CR6 | [
"Q54G11",
"Q54QM7",
"Q86CR8",
"Q86CS0",
"Q86CS1",
"Q54SX2",
"Q86CR9",
"Q54NL4",
"Q86CR7",
"Q54NA2",
"Q86CR5",
"Q54J54",
"Q86K79",
"Q54HA2",
"Q55EL2",
"Q55CE3",
"Q553S4",
"Q54Q21",
"Q54S77",
"Q54DY0",
"Q54JI9",
"Q86CS2"
] | [
"IPR007242",
"IPR029071"
] | {"IPR029071": [16, 124], "IPR007242": [31, 124]} | - Autophagy protein 5
- Ubiquitin-like modifier-activating enzyme atg7
- Autophagy-related protein 3
- Protein tipD
- Ubiquitin-like-conjugating enzyme ATG10
- Autophagy-related protein 18
- Autophagy-related protein 8
- Serine/threonine-protein kinase atg1
- Probable serine/threonine-protein kinase vps15
- Autophagy-r... | - IPR007242: Ubiquitin-like protein Atg12 (family) [31-124]
- IPR029071: Ubiquitin-like domain superfamily (homologous_superfamily) [16-124] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0051179 (localization), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies int... |
Q5A1Z5 | Autophagy-related protein 13 | Plays a key role in autophagy. Activates the atg1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy (By similarity). Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation (By similarity). Seems to play a role in the switching ... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 761 | Cytoplasm. Preautophagosomal structure | MLSDFKQQQQQKHHSHNPPNSHDDTQTKLQVAKLTQVIQKFFTKAAQIILESRAYPETSTPSLYPTKEESSKINKWFNLYMTNIPDSCKDDLKLWKGVDLTTIPPMIIETYIDLRSLPADQTLVLMDDEKHPWTVAKSRGKKQEVVLERWLIEFEPNTTDATVMVEELPLSYKQAIVLFRSIYGFTRLMPAFKVKKNLQNKLPLGNKILDGNQPISSKGRIGLSKPIINTRTNESHMTQKYFQPVHTSLGTLKISVAYRMDSEFCLHENEELLSSHFHKRDEEETKKKVSSSVSPLSSGTSLKETSTSPRKSQPPIRIQP... | [
"GO:0006914",
"GO:0006950",
"GO:0006974",
"GO:0006995",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009267",
"GO:0009987",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0042594",
"GO:0042710",
"GO:0043562",
"GO:0044010",
"GO:0050896",
"GO:0051703",
"GO:0051716",
"GO:0061919"... | [
"GO:0006914",
"GO:0006950",
"GO:0006974",
"GO:0006995",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009267",
"GO:0009987",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0042594",
"GO:0042710",
"GO:0043562",
"GO:0044010",
"GO:0050896",
"GO:0051703",
"GO:0051716",
"GO:0061919"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005773",
"GO:0005776",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q5A1Z5-F1-model_v6.pdb | 237561.Q5A1Z5 | [
"Q59V90",
"Q5ANC9",
"Q5ABQ7",
"Q59X11",
"P0C075",
"Q5A4N0",
"Q5A649",
"Q5A2C3",
"Q5AD78",
"Q5AMN3",
"A0A1D8PFB7",
"Q5ACZ2",
"Q59MN0",
"Q59Q11",
"Q5AI71",
"A0A1D8PJF0",
"A0A1D8PHX3",
"A0A1D8PLM0",
"A0A1D8PJ80"
] | [
"IPR040182",
"IPR036570",
"IPR018731"
] | {"IPR036570": [31, 267], "IPR040182": [27, 758], "IPR018731": [38, 264]} | - Serine/threonine-protein kinase ATG1
- Autophagy-related protein 17
- Autophagy-related protein 101
- Autophagy-related protein 11
- Autophagy-related protein 9
- Putative lipase ATG15
- Serine/threonine-protein kinase TOR
- Ubiquitin-binding TORC1 subunit
- Vacuolar protein 8
- Target of rapamycin complex subunit LS... | - IPR040182: Autophagy-related protein 13 (family) [27-758]
- IPR036570: HORMA domain superfamily (homologous_superfamily) [31-267]
- IPR018731: Autophagy-related protein 13, N-terminal (domain) [38-264] | Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0030234 (enzyme regulator activity), GO:0140677 (molecular function activator activity), GO:0019207 (kinase regulator activity), GO:0008047 (enzyme activator activity), GO:0019209 (kinase activator activity)... |
Q5A950 | Sterol 3-beta-glucosyltransferase | Sterol glycosyltransferase responsible for the glycosylation of ergosterol to form ergosterol-glucoside | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,512 | Cytoplasm. Membrane; Peripheral membrane protein | MSFYKKVTRGLATPLQGSINLFSGSPNVSGDEGTDADNENPEHRTTYHSLSGRVNHDDDDEDVAKLEDIVGFFTGLLNTTTVCAGLGSLNNLKKHYLDEFIKKSALNPLRPQNYGPETSSKLNNNSIEELLNNGDTSLEKVRKMSLYDFDEHTSDSEEEDSADKEEESIAENLKPGKSGKARNHPRDSRTTATLITTQITRTKTATTATPTPTPTSSVDTDVTDVTEPIGKVTTKIPEEQLQGLNPLQKSVVKNLDPHHVREGVLIKVKNSETPLKNDRQELLEKIQLRLKIADKLQRVFDLSDEDTFCGNYSAWLIKDV... | [
"GO:0003674",
"GO:0003824",
"GO:0008194",
"GO:0016740",
"GO:0016757",
"GO:0016758",
"GO:0016906",
"GO:0035251",
"GO:0046527"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0008194",
"GO:0016740",
"GO:0016757",
"GO:0016758",
"GO:0016906",
"GO:0035251",
"GO:0046527"
] | [] | AF-Q5A950-F1-model_v6.pdb | 237561.Q5A950 | [
"Q5AMN3",
"Q5ADK6"
] | [
"IPR004182",
"IPR004276",
"IPR011993",
"IPR001849",
"IPR050426",
"IPR002213",
"IPR048065",
"IPR010610"
] | {"IPR011993": [351, 922], "IPR050426": [821, 1462], "IPR002213": [1015, 1429], "IPR004182": [294, 924], "IPR001849": [359, 522], "IPR048065": [825, 917], "IPR004276": [1017, 1152], "IPR010610": [1308, 1414]} | - Sorting nexin-4
- Autophagy-related protein 11 | - IPR004182: GRAM domain (domain) [294-924]
- IPR004276: Glycosyltransferase family 28, N-terminal domain (domain) [1017-1152]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [351-922]
- IPR001849: Pleckstrin homology domain (domain) [359-522]
- IPR050426: Glycosyltransferase 28 (family) [821-1462]
- I... | Molecular Function (MF): GO:0003674 (molecular function), GO:0060090 (molecular adaptor activity), GO:0030674 (protein-macromolecule adaptor activity), GO:0043495 (protein-membrane adaptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0050896 ... |
Q59LR2 | Serine/threonine-protein kinase MEC1 | Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Recruited to DNA lesions in order to initiate the... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 2,325 | Nucleus. Note=Localizes to nuclear DNA repair foci in response to DNA double strand breaks | MTSNQSISTTELLQFLTDIETNIDDHETDFRKLLLYLLRFTNEKLIVIAQEENKTPTELQLLSKLIDTIELVLSKKTPLLSTLLTIEDVNIIHTTGSGSLVYEVPLHEWCISFALSHIPNFVSHTAGLNQLKRLVFLIVNLVSTQLHSFKVIKSTRIHLLKTLDDNLNFCLQNLLSANTFLFKSKLTTAVNLFSIVHDYDISQKLSLNLNNYQLKFESCSRKIWFILNEISLVSELDNLNLLDCLKSVFILDQSSALVLNVSVGWNQIGFLLSCIVEYLQQDFRTLDSNTNNFEFVNLNRSISLSLLNVYIVCFDKDLLE... | [
"GO:0000045",
"GO:0006914",
"GO:0006950",
"GO:0006974",
"GO:0006996",
"GO:0007033",
"GO:0007154",
"GO:0007165",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009894",
"GO:0009987",
"GO:0010506",
"GO:0016043",
"GO:0016236",
"GO:0019222",
"GO:0022607",
"GO:0023052",
"GO:0030447"... | [
"GO:0000045",
"GO:0006914",
"GO:0006950",
"GO:0006974",
"GO:0006996",
"GO:0007033",
"GO:0007154",
"GO:0007165",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009894",
"GO:0009987",
"GO:0010506",
"GO:0016043",
"GO:0016236",
"GO:0019222",
"GO:0022607",
"GO:0023052",
"GO:0030447"... | [] | [] | AF-Q59LR2-F1-model_v6.pdb | 237561.Q59LR2 | [
"Q59NG5",
"A0A1D8PDY7",
"A0A1D8PFE6",
"A0A1D8PS48",
"Q59Z33",
"A0A1D8PHD2",
"A0A1D8PJD1",
"Q59NG2",
"A0A1D8PQI3",
"A0A1D8PF46",
"A0A1D8PPB3",
"A0A1D8PNH8",
"A0A1D8PRA7",
"Q5A0A0",
"A0A1D8PI62",
"A0A1D8PCN8",
"A0A1D8PU93",
"Q59WC8",
"A0A1D8PKX2",
"Q5A6K8",
"Q5ABE2",
"Q5A4N5"... | [
"IPR056802",
"IPR050517",
"IPR012993",
"IPR016024",
"IPR003152",
"IPR011009",
"IPR014009",
"IPR057564",
"IPR036940",
"IPR003151",
"IPR000403",
"IPR018936",
"IPR058681"
] | {"IPR016024": [277, 1102], "IPR011009": [1969, 2321], "IPR036940": [2129, 2322], "IPR050517": [99, 2324], "IPR058681": [24, 731], "IPR012993": [847, 953], "IPR056802": [1204, 1437], "IPR014009": [1363, 1886], "IPR003151": [1605, 1801], "IPR057564": [1822, 1917], "IPR000403": [1993, 2324], "IPR003152": [2293, 2325], "IP... | - Serine/threonine-protein kinase RAD53
- Serine/threonine-protein kinase TEL1
- DNA damage checkpoint protein LCD1
- Checkpoint protein
- Chromatin-binding protein
- Checkpoint protein RAD24
- non-specific serine/threonine protein kinase
- Cyclin-dependent kinase 1
- DNA repair protein rad9
- Serine/threonine protein ... | - IPR056802: Serine/threonine-protein kinase ATR-like, M-HEAT region (domain) [1204-1437]
- IPR050517: DNA Damage Response and Repair Kinase (family) [99-2324]
- IPR012993: UME domain (domain) [847-953]
- IPR016024: Armadillo-type fold (homologous_superfamily) [277-1102]
- IPR003152: FATC domain (domain) [2293-2325]
- ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotrans... |
Q5W7F4 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | Involved in larval molting and metamorphosis. May degrade extracellular matrix (ECM) and basement membrane (BM) during the development of organs to allow degeneration and remodeling of tissues | Bombyx mori (Silk moth) | 1,007 | Secreted, extracellular space, extracellular matrix | MPCCLWAALSLLLAVVGAGAWTPPRQPLLLTPRHRRHAQETHHLRLLGWDLKLKENKAIRSPYYKECQFFTGRVLHEEGSAVTVTECDGQLYGLLQVGGEEFVLQPTRTQEKHVLRRRDVTHSERSAEYNLTGDTVIDLDLDFDEDDDLLPTSHVHPRHSDHSDKEYFHDMHLFRRPASGVKGLWLELAIVADNTMLKFHGRERVKHYILALMNIVSAIFNDPSLGSNITLVINKLFLYEDKDIILKYGNIKKSLEAINKWNYRHLMKLPEGSTGWDATIWLTRSQLGGPSGFAPVGGVCTKTRSAAIDRDEGLTSAFVI... | [
"GO:0002164",
"GO:0002165",
"GO:0002168",
"GO:0007275",
"GO:0007552",
"GO:0008150",
"GO:0009791",
"GO:0022404",
"GO:0032501",
"GO:0032502",
"GO:0035074",
"GO:0035209",
"GO:0042303",
"GO:0048856"
] | [
"GO:0002164",
"GO:0002165",
"GO:0002168",
"GO:0007275",
"GO:0007552",
"GO:0008150",
"GO:0009791",
"GO:0022404",
"GO:0032501",
"GO:0032502",
"GO:0035074",
"GO:0035209",
"GO:0042303",
"GO:0048856"
] | [] | [] | AF-Q5W7F4-F1-model_v6.pdb | null | null | [
"IPR024079",
"IPR000884",
"IPR041645",
"IPR001590",
"IPR036383",
"IPR006586",
"IPR050439"
] | {"IPR024079": [183, 393], "IPR036383": [461, 959], "IPR050439": [208, 964], "IPR001590": [184, 380], "IPR041645": [400, 465], "IPR006586": [402, 468], "IPR000884": [482, 952]} | - IPR024079: Metallopeptidase, catalytic domain superfamily (homologous_superfamily) [183-393]
- IPR000884: Thrombospondin type-1 (TSP1) repeat (repeat) [482-952]
- IPR041645: ADAMTS, cysteine-rich domain 2 (domain) [400-465]
- IPR001590: Peptidase M12B, ADAM/reprolysin (domain) [184-380]
- IPR036383: Thrombospondin ty... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of bio... | |
Q5W7F3 | A disintegrin and metalloproteinase with thrombospondin motifs like | Involved in larval molting and metamorphosis. May degrade extracellular matrix (ECM) and basement membrane (BM) during the development of organs to allow degeneration and remodeling of tissues | Bombyx mori (Silk moth) | 693 | Secreted, extracellular space, extracellular matrix | MESSVATHWLSAFVILCSFITTQSLNNKIHEHMTIDELRNVFHVEHHSRVPEYHLVQLTHHLARRNIPTSHPANSNSADSGKTPHLKTEKVTKGGYKAPSLLNDEMFVEAKKRIEDVDIMGDPNSTVSVDFKVQSSEFGDSESLSDKEHSAESQEDGVHKIDLEAFGRQLKLVLKKQEGLIKKDGLKVWKALKNETQPHGVDYEEMITEDDEEFGDLYQDEENGAALLIRRHPKHGKLVVEGSIGHDLVIRPIPDTMTSPAQDDEMFMDPSSMADMVSIDTGLPIMKRKKEEQDRLQEALNGAQHVIIKRDPAEVDHMSD... | [
"GO:0002164",
"GO:0002165",
"GO:0002168",
"GO:0007275",
"GO:0007552",
"GO:0008150",
"GO:0009791",
"GO:0022404",
"GO:0032501",
"GO:0032502",
"GO:0035074",
"GO:0035209",
"GO:0042303",
"GO:0048856"
] | [
"GO:0002164",
"GO:0002165",
"GO:0002168",
"GO:0007275",
"GO:0007552",
"GO:0008150",
"GO:0009791",
"GO:0022404",
"GO:0032501",
"GO:0032502",
"GO:0035074",
"GO:0035209",
"GO:0042303",
"GO:0048856"
] | [] | [] | AF-Q5W7F3-F1-model_v6.pdb | null | null | [
"IPR024079",
"IPR001590",
"IPR034030",
"IPR041645"
] | {"IPR024079": [352, 585], "IPR001590": [353, 585], "IPR034030": [353, 581], "IPR041645": [596, 659]} | - IPR024079: Metallopeptidase, catalytic domain superfamily (homologous_superfamily) [352-585]
- IPR001590: Peptidase M12B, ADAM/reprolysin (domain) [353-585]
- IPR034030: Salivary gland reprolysin domain (domain) [353-581]
- IPR041645: ADAMTS, cysteine-rich domain 2 (domain) [596-659] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity), GO:0008237 (metallopeptidase activity), GO:0004222 (metalloendopeptidase... | |
C1P605 | Uncharacterized protein AzuC | null | Escherichia coli (strain K12) | 28 | Cell inner membrane; Peripheral membrane protein | MKLRKILKSMFNNYCKTFKDVPPGNMFR | [
"GO:0003674",
"GO:0008047",
"GO:0030234",
"GO:0098772",
"GO:0140677"
] | [] | [
"GO:0003674",
"GO:0008047",
"GO:0030234",
"GO:0098772",
"GO:0140677"
] | [] | AF-C1P605-F1-model_v6.pdb | 511145.b4663 | [
"Q47234",
"C1P5Z8"
] | [
"IPR049862"
] | {"IPR049862": [2, 27]} | - Aerobic glycerol-3-phosphate dehydrogenase
- Uncharacterized membrane protein YkgR | - IPR049862: Stress response protein AzuC (family) [2-27] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0051703 (biological process involved in intraspecies interaction between organisms),... |
Q1RM09 | Brain acid soluble protein 1 homolog | null | Danio rerio (Zebrafish) (Brachydanio rerio) | 197 | Cell membrane; Lipid-anchor | MGGKLSKKKKGYNVNDEKAKEKDAKTEGASAEESEAPKENKEDAAAATETTNDTAAAAKEATPTADSNSTAPKEEEKSAAPPKKEEPAANANANAPKASDAKTSEAAKAEPAKSPDAPPVKAEEKSAPSAAPANEKEPAKEAAKDPAPAVAAASESKPDAESKKTEAPPTKESAPAEPITTETSPAPNKEQAVAVQD | [
"GO:0008150",
"GO:0022603",
"GO:0045765",
"GO:0045766",
"GO:0048518",
"GO:0050789",
"GO:0050793",
"GO:0051094",
"GO:0051239",
"GO:0051240",
"GO:0065007",
"GO:1901342",
"GO:1904018",
"GO:2000026"
] | [
"GO:0008150",
"GO:0022603",
"GO:0045765",
"GO:0045766",
"GO:0048518",
"GO:0050789",
"GO:0050793",
"GO:0051094",
"GO:0051239",
"GO:0051240",
"GO:0065007",
"GO:1901342",
"GO:1904018",
"GO:2000026"
] | [] | [] | AF-Q1RM09-F1-model_v6.pdb | 7955.ENSDARP00000069875 | [
"Q6DG93",
"A0A140LG11"
] | [
"IPR008408"
] | {"IPR008408": [1, 197]} | - Calphotin | - IPR008408: Brain acid soluble protein 1 (family) [1-197] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellul... |
Q59U10 | Biofilm and cell wall regulator 1 | Transcription factor which acts as a master regulator of biofilm formation. Biofilms play an important role in pathogenesis and produce many infections such as oropharyngeal candidiasis or vulvovaginal candidiasis. Controls the expression of genes that govern cell-surface properties such as ALS1, ALS3, HWP1 and HYR1. D... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 740 | Nucleus | MSGTSQVLQNDSHQSQHASMAYNQRQPMMYPPPPQQQPLHSQNSLPPLPPIPAPSLPPISNNISNGNTNELNNNNQQQQQHGQPPLPPPPINANQQYYAVPPLRAPPPLNTLSSVVNSLPTLTPTLTNATHSTMSSNSSAESSASSSSNSITKPKSKRSSKGRVFQCTGYPGCNMSFTRSEHLARHKRKHTGERPFTCPYCSKNFSRLDNLRQHKQTVHAYETYLTKDNRDSKLLIERSKSKKKLKQQEKKAQQQAQLQAQAQAQAQAQVHMQQHQQNGYNFQPPYPQFHNQYYANNQYQGPQPPPPPAPQQQVPGQQQP... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0007155",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010570",
"GO:0010604",
"GO:0010810",
"GO:0010811",
"GO:0019219",
"GO:0019222",
"GO:0030155"... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0007155",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010570",
"GO:0010604",
"GO:0010810",
"GO:0010811",
"GO:0019219",
"GO:0019222",
"GO:0030155"... | [
"GO:0001216",
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003700",
"GO:0005488",
"GO:0043565",
"GO:0140110"
] | [
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q59U10-F1-model_v6.pdb | 237561.Q59U10 | [
"Q59TL7",
"Q59LY1",
"Q5AB65",
"Q59WZ4",
"A0A1D8PFP2",
"Q59S18",
"Q874L3",
"Q59XB5",
"Q7Z883",
"Q5ANJ4",
"Q59RR0",
"Q59ME1",
"Q5A8T4",
"Q5ACU9"
] | [
"IPR013087",
"IPR051059",
"IPR036236"
] | {"IPR036236": [170, 216], "IPR051059": [141, 524], "IPR013087": [165, 224]} | - Transcription activator TEC1
- Enhanced filamentous growth protein 1
- Biofilm regulator 1
- Agglutinin-like protein 3
- Agglutinin-like protein 1
- Hyphal wall protein 1
- Transcription factor ROB1
- Transcription factor NDT80
- Transcriptional repressor TUP1
- Transcriptional repressor TUP1 | - IPR013087: Zinc finger C2H2-type (domain) [165-224]
- IPR051059: Transcription factor verF-like (family) [141-524]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [170-216] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0003676 (nucleic acid binding), GO:0003677 (... |
P0A6E9 | ATP-dependent dethiobiotin synthetase BioD 2 | Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring | Escherichia coli (strain K12) | 231 | Cytoplasm | MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGSKETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANLTEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIANDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLAMLRSVLAVDRVTV | [
"GO:0006082",
"GO:0006766",
"GO:0006768",
"GO:0006790",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009102",
"GO:0009110",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0032787",
"GO:0042364",
"GO:0043436",
"GO:0043603",
"GO:0043604",
"GO:0044272",
"GO:0044281",
"GO:0044283"... | [
"GO:0006082",
"GO:0006766",
"GO:0006768",
"GO:0006790",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009102",
"GO:0009110",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0032787",
"GO:0042364",
"GO:0043436",
"GO:0043603",
"GO:0043604",
"GO:0044272",
"GO:0044281",
"GO:0044283"... | [
"GO:0003674",
"GO:0003824",
"GO:0004141",
"GO:0005488",
"GO:0005515",
"GO:0016874",
"GO:0016879",
"GO:0016882",
"GO:0042802",
"GO:0042803",
"GO:0046983"
] | [] | AF-P0A6E9-F1-model_v6.pdb | 511145.b1593 | [
"Q2M777",
"Q2MBJ1",
"Q2MBJ5",
"Q2MBJ3",
"Q2MBJ2",
"Q2MBJ4"
] | [
"IPR004472",
"IPR027417"
] | {"IPR027417": [1, 220], "IPR004472": [1, 220]} | - Biotin synthase
- Adenosylmethionine-8-amino-7-oxononanoate aminotransferase
- 8-amino-7-oxononanoate synthase
- ATP-dependent dethiobiotin synthetase BioD 1
- Malonyl-[acyl-carrier protein] O-methyltransferase
- Pimeloyl-[acyl-carrier protein] methyl ester esterase | - IPR004472: Dethiobiotin synthase BioD (family) [1-220]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [1-220] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:0016874 (ligase activity), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate... |
Q9LFL7 | Inactive serine/threonine-protein kinase BKN1 | Collaboratively with BKN2/SZE2, involved in compatible pollen-stigma interactions | Arabidopsis thaliana (Mouse-ear cress) | 331 | Cell membrane; Lipid-anchor; Cytoplasmic side. Nucleus. Note=Partial observation into the nucleus | MGNCLKHFKQQLPSIAPKPLIIPPIFSARKRESESLQIRGLKKATKKFRQDRVVECEDYSVRKFYKGYIDETTFAPSRAGTGIAVSVMECDSSRSLQDWMAVVRSLGQLSHQNLVNFLGYCCEDNKPFFLVFEYSHKGSLDSHIFGKEEEALPWEIRVKIAIGTAQGLAFLHSIKNSPLNRELRMHNIMLDEQYNAKLFYLEPTKRSLVDEGLKRGRFTYLSPEWGSLGILDMTTDVYIFGMILLELLMGSKDRKKIKEEQGLVDYWTSSFLPDNYKIEEIIDPRLGSDYSANAATQMGTLINRCTAHNTKKRPLMQQVL... | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-Q9LFL7-F1-model_v6.pdb | 3702.Q9LFL7 | [
"Q1G378",
"Q9LHM1",
"F4JLP8"
] | [
"IPR001245",
"IPR000719",
"IPR011009",
"IPR050823"
] | {"IPR011009": [77, 324], "IPR050823": [35, 326], "IPR000719": [58, 328], "IPR001245": [66, 321]} | - Leucine-rich repeat (LRR) family protein
- RNA-binding (RRM/RBD/RNP motifs) family protein
- non-specific serine/threonine protein kinase | - IPR001245: Serine-threonine/tyrosine-protein kinase, catalytic domain (domain) [66-321]
- IPR000719: Protein kinase domain (domain) [58-328]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [77-324]
- IPR050823: Plant Serine/Threonine-Protein Kinase (family) [35-326] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:0009875 (p... |
P22004 | Bone morphogenetic protein 6 | Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes including cartilage and bone formation. Also plays an important role in the regulation of HAMP/hepcidin expression and iron metabolism by acting as a ligand for hemojuvelin/HJV. Also acts to promote expression of HAMP, ... | Homo sapiens (Human) | 513 | Secreted | MPGLGRRAQWLCWWWGLLCSCCGPPPLRPPLPAAAAAAAGGQLLGDGGSPGRTEQPPPSPQSSSGFLYRRLKTQEKREMQKEILSVLGLPHRPRPLHGLQQPQPPALRQQEEQQQQQQLPRGEPPPGRLKSAPLFMLDLYNALSADNDEDGASEGERQQSWPHEAASSSQRRQPPPGAAHPLNRKSLLAPGSGSGGASPLTSAQDSAFLNDADMVMSFVNLVEYDKEFSPRQRHHKEFKFNLSQIPEGEVVTAAEFRIYKDCVMGSFKNQTFLISIYQVLQEHQHRDSDLFLLDTRVVWASEEGWLEFDITATSNLWVVT... | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0032991",
"GO:0110165",
"GO:0150005"
] | [] | [] | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0032991",
"GO:0110165",
"GO:0150005"
] | AF-P22004-F1-model_v6.pdb | 9606.ENSP00000283147 | [
"Q5TBA1",
"Q9BQB4",
"Q8NEN8",
"Q9UQA1",
"Q8IXV8",
"Q9H772",
"Q8WVJ5",
"Q92859",
"Q9UCU4",
"Q04771",
"Q13485",
"P21810",
"Q8N936",
"Q5TCK6",
"P12643",
"Q13253",
"P78366",
"Q92474",
"Q9BY68",
"Q4VAV0",
"Q8TF36",
"Q9UM80",
"Q9UP52",
"Q9P0Z5",
"Q647K2",
"Q96L68",
"Q9H... | [
"IPR017948",
"IPR001111",
"IPR029034",
"IPR015615",
"IPR001839"
] | {"IPR029034": [400, 513], "IPR015615": [32, 513], "IPR001111": [63, 362], "IPR001839": [394, 513], "IPR017948": [430, 445]} | - Bone morphogenetic protein receptor type-1A
- Activin receptor type-1
- Bone morphogenetic protein receptor type-1B
- Activin receptor type-2A
- Bone morphogenetic protein receptor type-2
- Hemojuvelin
- Activin receptor type-2B
- Noggin
- Chordin
- Bone morphogenetic protein 4 | - IPR017948: Transforming growth factor beta, conserved site (conserved_site) [430-445]
- IPR001111: TGF-beta, propeptide (domain) [63-362]
- IPR029034: Cystine-knot cytokine (homologous_superfamily) [400-513]
- IPR015615: Transforming growth factor-beta-related (family) [32-513]
- IPR001839: Transforming growth factor... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0033612 (receptor serine/threonine kinase binding), GO:0070696 (transmembrane receptor protein serine/threonine kinase binding)
Biological Process (BP): GO:0008150 (b... |
Q14692 | Ribosome biogenesis protein BMS1 homolog | GTPase required for the synthesis of 40S ribosomal subunits and for processing of pre-ribosomal RNA (pre-rRNA) at sites A0, A1, and A2. Controls access of pre-rRNA intermediates to RCL1 during ribosome biogenesis by binding RCL1 in a GTP-dependent manner, and delivering it to pre-ribosomes. GTP-binding and/or GTP hydro... | Homo sapiens (Human) | 1,282 | Nucleus, nucleolus | MEAKDQKKHRKKNSGPKAAKKKKRLLQDLQLGDEEDARKRNPKAFAVQSAVRMARSFHRTQDLKTKKHHIPVVDRTPLEPPPIVVVVMGPPKVGKSTLIQCLIRNFTRQKLTEIRGPVTIVSGKKRRLTIIECGCDINMMIDLAKVADLVLMLIDASFGFEMETFEFLNICQVHGFPKIMGVLTHLDSFKHNKQLKKTKKRLKHRFWTEVYPGAKLFYLSGMVHGEYQNQEIHNLGRFITVMKFRPLTWQTSHPYILADRMEDLTNPEDIRTNIKCDRKVSLYGYLRGAHLKNKSQIHMPGVGDFAVSDISFLPDPCALP... | [
"GO:0008150",
"GO:0009987",
"GO:0022613",
"GO:0042254",
"GO:0042274",
"GO:0044085",
"GO:0071840"
] | [
"GO:0008150",
"GO:0009987",
"GO:0022613",
"GO:0042254",
"GO:0042274",
"GO:0044085",
"GO:0071840"
] | [] | [] | AF-Q14692-F1-model_v6.pdb | 9606.ENSP00000363642 | [
"Q8N6Z7",
"Q9H9F8",
"Q9UIX2",
"Q9BRZ1",
"Q6IRL7",
"Q96E99",
"Q9Y4C7",
"Q8NDL5",
"Q9UNQ2",
"Q9Y505",
"Q9BYG3",
"Q9NQT4",
"Q96NM6",
"Q9NW23",
"Q9BWK6",
"Q9UPI6",
"Q6IQ15",
"Q9Y482",
"Q9Y221",
"Q96BN0",
"Q96L80",
"Q9NXF1",
"Q9NZX3",
"Q9NST5",
"P62857",
"Q9NQ05",
"Q96... | [
"IPR012948",
"IPR030387",
"IPR027417",
"IPR039761",
"IPR037875",
"IPR007034"
] | {"IPR027417": [78, 245], "IPR039761": [591, 1256], "IPR037875": [44, 273], "IPR030387": [80, 245], "IPR012948": [231, 317], "IPR007034": [812, 1105]} | - U3 small nucleolar RNA-associated protein 15 homolog
- WD repeat-containing protein 75
- HEAT repeat-containing protein 1
- U3 small nucleolar RNA-associated protein 4 homolog
- Nucleolar protein 56
- U3 small nucleolar RNA-associated protein 6 homolog
- KRR1 small subunit processome component homolog
- WD repeat-con... | - IPR012948: AARP2CN (domain) [231-317]
- IPR030387: Bms1/Tsr1-type G domain (domain) [80-245]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [78-245]
- IPR039761: Ribosome biogenesis protein Bms1/Tsr1 (family) [591-1256]
- IPR037875: Ribosome biogenesis protein Bms1, N-termin... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), ... |
Q5ABU8 | Beta-mannosyltransferase 6 | Beta-mannosyltransferase involved in cell wall biosynthesis. Required for beta-1,2-mannose transfer on phospholipomannan. Required for pro-inflammatory response in macrophages through phospholipomannan- induced TNF-alpha production | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 646 | Membrane; Single-pass type II membrane protein | MGNYKPSIKQYVVTVKAIKSSQFGRLGICAVVLLFVLGYPFYFISNNPFDTSIRYQYVDPYNDTTRKYTTIEKQHTDIGGNGTTILYPKNLQLDQTALSQLLNTTETTNPFVQYIGNSSSIAFSQLNQTLVNHSIQVFDPFSNSDNCSDLMTETQLTISQNIIIKESFEIMVKRLMHQLDTEPAFKELAPFFQNKLSLHLRMRSYHKHFYKFARTSVWLKDYGVHLMISRVIYSQKGKKGDPQISLLYTQLYDTNWQELTNTDLLVSMQDITGEYKLEKLQFPRFLPMPFYYNPKLTKGRWYGPEDARIMLVKNQLDMEE... | [
"GO:0006629",
"GO:0006643",
"GO:0006664",
"GO:0006665",
"GO:0006687",
"GO:0006688",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009247",
"GO:0009987",
"GO:0030148",
"GO:0044238",
"GO:0046467",
"GO:1901135",
"GO:1901137",
"GO:1903509"
] | [
"GO:0006629",
"GO:0006643",
"GO:0006664",
"GO:0006665",
"GO:0006687",
"GO:0006688",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009247",
"GO:0009987",
"GO:0030148",
"GO:0044238",
"GO:0046467",
"GO:1901135",
"GO:1901137",
"GO:1903509"
] | [] | [] | AF-Q5ABU8-F1-model_v6.pdb | 237561.Q5ABU8 | null | [
"IPR021988"
] | {"IPR021988": [146, 624]} | - IPR021988: Beta-mannosyltransferase (family) [146-624] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016757 (glycosyltransferase activity), GO:0016758 (hexosyltransferase activity), GO:0000030 (mannosyltransferase activity)
Biological Process (BP): GO:0008150 (biological process), GO:000815... | |
P0C739 | Protein BNLF2a | Participates in viral evasion from HLA class I-restricted T- cell immunity. Associates with host TAP1 and TAP2 and prevents TAP- mediated peptide transport and subsequent loading | Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4) | 60 | Host endoplasmic reticulum membrane; Single-pass membrane protein | MVHVLERALLEQQSSACGLPGSSTETRPSHPCPEDPDVSRLRLLLVVLCVLFGLLCLLLI | [
"GO:0002376",
"GO:0002474",
"GO:0002483",
"GO:0008150",
"GO:0019882",
"GO:0019883",
"GO:0019885",
"GO:0048002",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031984",
"GO:0042175",
"GO:0043226",
"GO:0043227"... | [
"GO:0002376",
"GO:0002474",
"GO:0002483",
"GO:0008150",
"GO:0019882",
"GO:0019883",
"GO:0019885",
"GO:0048002"
] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031984",
"GO:0042175",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0098827",
"GO:0110165"
] | null | null | null | [
"IPR058026"
] | {"IPR058026": [1, 60]} | - IPR058026: BNLF2a (family) [1-60] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050792 (re... | |
A1ZB64 | Bomanin Short 6 | Secreted immune-induced peptide induced by Toll signaling. Has a role in resistance to bacterial and fungal infections. The strength of antimicrobial activity appears to correlate with the overall level of expression | Drosophila melanogaster (Fruit fly) | 40 | Secreted | MKLLSITFLFGLLALASANPLSPGNVIINGDCKVCNIRGD | [
"GO:0008150",
"GO:0009636",
"GO:0010046",
"GO:0042221",
"GO:0050896"
] | [
"GO:0008150",
"GO:0009636",
"GO:0010046",
"GO:0042221",
"GO:0050896"
] | [] | [] | AF-A1ZB64-F1-model_v6.pdb | 7227.FBpp0085906 | [
"B7FNR2",
"Q9V8F9",
"A1ZB61",
"Q9W2Q9",
"Q9VD49",
"Q9V8F6",
"A0A0B4K792",
"Q8SYA4",
"Q9V8G0",
"D4G7G1"
] | [
"IPR013172"
] | {"IPR013172": [1, 36]} | - Bomanin Tailed 2
- Bomanin short 4
- Bomanin bicipital 2, isoform A
- Bomanin Short 2
- Bomanin tailed 1
- Daisho1
- Bomanin tailed 3, isoform A
- Bomanin Short 5
- Bomanin Short 1
- Bomanin Short 3 | - IPR013172: Bomanin (family) [1-36] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0097367 (carbohydrate derivative binding), GO:0005515 (protein binding), GO:0030546 (signaling receptor activator activity), GO:0008061 (chitin binding)
Biological Process (BP): GO:0008... |
Q59LY1 | Biofilm regulator 1 | Transcription factor required for hyphal growth, biofilm formation, and virulence. Promotes formation of both conventional and pheromone-stimulated biofilms. Binds and recruits HDA1 to promoters of hypha-specific genes in a rapamycin-dependent manner. Involved in the switch between two heritable states, the white and o... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 422 | Nucleus | MSSSSSLSSSTTTATTTSARIRLPSISELTSRSTISGGSNNGNGSALKSQISPRLSDTSRILPSILKNTSGSSTPTSSSTPFKCPPIKSTVGGTLSSGNTQSNYVLGNTKINSLPRLSSPTLPVKVQPQQQPQLPPASSLSPVTRVINTPPQQPQSVSASTSPNTQYQYYQYQQQSSPIQQQQQQQQATPAATPTVMQMAQNQPSHPAPLQYATQQYYPQPVYYQSPAGVPPPPPSVTHQGHIIAVHQHPGHLPQVGVNGMPPNVGYTIVQPEIVNKSTNRCHRCGTTETPEWRRGPKGVRTLCNACGLFHAKLVKRKGA... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0008150",
"GO:0009267",
"GO:0009607",
"GO:0009889",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010570",
"GO:0019219",
"GO:0019222",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036170"... | [
"GO:0002831",
"GO:0002833",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0008150",
"GO:0009267",
"GO:0009607",
"GO:0009889",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010570",
"GO:0019219",
"GO:0019222",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036170"... | [
"GO:0001216",
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003700",
"GO:0005488",
"GO:0043565",
"GO:0140110"
] | [
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q59LY1-F1-model_v6.pdb | 237561.Q59LY1 | [
"Q5A271",
"Q59TL7",
"Q59XB5",
"Q7Z883",
"A0A1D8PFP2",
"Q59U34",
"Q59ME1",
"Q5AMQ6",
"Q5ANJ4",
"Q5A0E5",
"Q5ACU9"
] | [
"IPR013088",
"IPR000679"
] | {"IPR013088": [274, 357], "IPR000679": [276, 331]} | - Biofilm and cell wall regulator 1
- Enhanced filamentous growth protein 1
- Transcription activator TEC1
- Transcription factor ROB1
- Transcription factor NDT80
- Transcriptional regulatory protein UME6
- Transcriptional regulator NRG1
- Transcriptional regulator of filamentous growth FLO8
- Repressor of filamentous... | - IPR013088: Zinc finger, NHR/GATA-type (homologous_superfamily) [274-357]
- IPR000679: Zinc finger, GATA-type (domain) [276-331] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0043565 (sequence-specific DNA binding)
Biological Process (BP): GO:0008150 (biologica... |
Q5VW32 | BRO1 domain-containing protein BROX | Nuclear envelope-associated factor that is involved in the nuclear envelope ruptures during interphase (NERDI) repair, where it is locally recruited by CHMP5 and reduces cytoskeletal stress through its action on SYN2 to help reseal the ruptured membrane | Homo sapiens (Human) | 411 | Nucleus membrane; Lipid-anchor. Note=During nuclear envelope repair, localizes at rupture sites where it is recruited by the CHMP7/ESCRT-III axis | MTHWFHRNPLKATAPVSFNYYGVVTGPSASKICNDLRSSRARLLELFTDLSCNPEMMKNAADSYFSLLQGFINSLDESTQESKLRYIQNFKWTDTLQGQVPSAQQDAVFELISMGFNVALWYTKYASRLAGKENITEDEAKEVHRSLKIAAGIFKHLKESHLPKLITPAEKGRDLESRLIEAYVIQCQAEAQEVTIARAIELKHAPGLIAALAYETANFYQKADHTLSSLEPAYSAKWRKYLHLKMCFYTAYAYCYHGETLLASDKCGEAIRSLQEAEKLYAKAEALCKEYGETKGPGPTVKPSGHLFFRKLGNLVKNTL... | [
"GO:0000278",
"GO:0000280",
"GO:0006996",
"GO:0006998",
"GO:0007049",
"GO:0007084",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0022402",
"GO:0022607",
"GO:0031468",
"GO:0044085",
"GO:0044091",
"GO:0048285",
"GO:0061024",
"GO:0071709",
"GO:0071763",
"GO:0071840"... | [
"GO:0000278",
"GO:0000280",
"GO:0006996",
"GO:0006998",
"GO:0007049",
"GO:0007084",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0022402",
"GO:0022607",
"GO:0031468",
"GO:0044085",
"GO:0044091",
"GO:0048285",
"GO:0061024",
"GO:0071709",
"GO:0071763",
"GO:0071840"... | [] | [] | AF-Q5VW32-F1-model_v6.pdb | 9606.ENSP00000343742 | [
"Q9H444",
"Q96CF2",
"Q9P026",
"Q9Y323"
] | [
"IPR038499",
"IPR004328",
"IPR038898"
] | {"IPR038499": [1, 374], "IPR038898": [2, 378], "IPR004328": [4, 411]} | - Charged multivesicular body protein 4b
- Charged multivesicular body protein 5
- Charged multivesicular body protein 4c
- Charged multivesicular body protein 4a | - IPR038499: BRO1 domain superfamily (homologous_superfamily) [1-374]
- IPR004328: BRO1 domain (domain) [4-411]
- IPR038898: BRO1 domain-containing protein BROX (family) [2-378] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulatio... |
P0AD14 | Sensor histidine kinase BtsS | Member of the two-component regulatory system BtsS/BtsR, which is part of a nutrient-sensing regulatory network composed of BtsS/BtsR, the low-affinity pyruvate signaling system YpdA/YpdB and their respective target proteins, BtsT and YhjX. Responds to depletion of nutrients, specifically serine, and the concomitant pr... | Escherichia coli (strain K12) | 561 | Cell inner membrane; Multi-pass membrane protein | MYDFNLVLLLLQQMCVFLVIAWLMSKTPLFIPLMQVTVRLPHKFLCYIVFSIFCIMGTWFGLHIDDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSMGGMTALSCMISTIVEGLLGGLVHSILIRRGRTDKVFNPITAGAVTFVAEMVQMLIILAIARPYEDAVRLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSATALKVAASTEGILRQGFNEVNSMKVAQVLYQELDIGAVAITDREKLLAFTGIGDDHHLPGKPISSTYTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPLRGENQ... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0031406",
"GO:0033293",
"GO:0036094",
"GO:0043167",
"GO:0043168",
"GO:0043177"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0031406",
"GO:0033293",
"GO:0036094",
"GO:0043167",
"GO:0043168",
"GO:0043177"
] | [] | AF-P0AD14-F1-model_v6.pdb | 511145.b2126 | [
"Q9ALR8",
"Q2M5W2",
"Q2M7K8",
"P77742",
"P77740",
"Q2MAV6"
] | [
"IPR003018",
"IPR050640",
"IPR036890",
"IPR011620",
"IPR010559",
"IPR029016"
] | {"IPR029016": [231, 356], "IPR036890": [423, 557], "IPR050640": [36, 560], "IPR011620": [27, 196], "IPR003018": [218, 365], "IPR010559": [371, 448]} | - Transcriptional regulatory protein-like BtsR
- Transcriptional regulatory protein BtsR
- Transcriptional regulatory protein BtsR
- Transcriptional regulatory protein BtsR
- Transcriptional regulatory protein YpdB
- Transcriptional regulatory protein YpdB
- Transcriptional regulatory protein YpdB
- Pyruvate/proton sym... | - IPR003018: GAF domain (domain) [218-365]
- IPR050640: Bacterial two-component sensor kinase systems (family) [36-560]
- IPR036890: Histidine kinase/HSP90-like ATPase superfamily (homologous_superfamily) [423-557]
- IPR011620: Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region (domain) [27-1... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process... |
P53705 | Bud site selection protein BUD4 | Required for establishment of the axial budding pattern in yeast cells. May be involved in the selection of future sites of septation in hyphal cells. Contributes to morphogenesis and is important for induction of hyphal growth. Also plays a role in epithelial adherence, and is involved in intestinal colonization and s... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,709 | Cell surface. Bud neck. Spore, perispore. Note=Localizes to a ring at the mother-bud neck of yeast and pseudohyphal cells. Localizes to single or double rings distal to the junction of the mother cell and germ tube in hyphal cells. Requires septins for proper localization. Also found at the cell-surface of blastospores | MQTSISTTTIEDHLHHYSPEESQKLLSRESSINTDLFKHENESVDLLLKEMNSTPSKLLPIDKHSHLQLQPQSSSASIFNSPTKPLNFPRTNSKPSLDPNSSSDTYTSEQDQEKGKEEKKDTAFQTSFDRNFDLDNSIDIQQTIQHQQQQPQQQQQLPQTDNNLIDEFSFQTPMTSTLDLTKQNPTVDKINENHAPTYINTSPNKSIMKKATPKASPKKVAFTATNPEIHHYPDNRVEEEDQSQQKEDSVEPPSIQHQWKDPSQFNYSDEDTNASVPPTPPLHTTKPTFAQLLNKNNEVNSEPEALTDMKLKHENFSNLS... | [
"GO:0000278",
"GO:0000280",
"GO:0000281",
"GO:0000282",
"GO:0000910",
"GO:0006996",
"GO:0007049",
"GO:0007114",
"GO:0007120",
"GO:0007155",
"GO:0007163",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0019954",
"GO:0022402",
"GO:0022413",
"GO:0022414",
"GO:0030010",
"GO:0030447"... | [
"GO:0000278",
"GO:0000280",
"GO:0000281",
"GO:0000282",
"GO:0000910",
"GO:0006996",
"GO:0007049",
"GO:0007114",
"GO:0007120",
"GO:0007155",
"GO:0007163",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0019954",
"GO:0022402",
"GO:0022413",
"GO:0022414",
"GO:0030010",
"GO:0030447"... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0050839"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005856",
"GO:0005933",
"GO:0005935",
"GO:0005938",
"GO:0005940",
"GO:0009986",
"GO:0030427",
"GO:0032156",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0071944",
"GO:0110165"
] | AF-P53705-F1-model_v6.pdb | 237561.P53705 | [
"A0A1D8PQK0",
"A0A1D8PM01",
"A0A1D8PD83",
"A0A1D8PP67",
"Q59W62",
"A0A1D8PDK6",
"Q5A6K6",
"A0A1D8PCY5"
] | [
"IPR001849",
"IPR011993",
"IPR052007"
] | {"IPR011993": [1561, 1686], "IPR052007": [42, 1709], "IPR001849": [1575, 1686]} | - Riboflavin synthase
- Cell division control protein 10
- Serine/threonine-protein kinase GIN4
- Septin
- DH domain-containing protein
- Septin
- 6,7-dimethyl-8-ribityllumazine synthase
- Axl2p | - IPR001849: Pleckstrin homology domain (domain) [1575-1686]
- IPR011993: PH-like domain superfamily (homologous_superfamily) [1561-1686]
- IPR052007: Bud site selection protein 4 (family) [42-1709] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), G... |
Q9Y7W4 | Serine/threonine-protein kinase BUR1 | Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced ... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 745 | Nucleus | MSVIAGHHVPRSNDQRQYDTPSVPINIAPDSEGHIHEMSRLKDYEVIEKLGQGTFGVVQKAKSKKDGSLVAIKQLINHSAKEGFPITAMREITILKQLNHKNILTIQDMIFEEPKMSNRTDIITMRGSFYTVTPYMSSDLVGLLENPKIKLELGQIKCIMQQLLKGIQYVHNQKFLHRDIKAANILIGQDGVLKIADFGLARIYHGNVPRLGMGPGGGEKAYTGLVVTRWYRPPEILLGERKYTTAVDLWGIGCVFAELFTGKPILVGKSDSHQAQIVFELVGSPLTWTDAAKLPNKNEYSCGLACKRSLEAKFASIMPT... | [
"GO:0000128",
"GO:0007155",
"GO:0007162",
"GO:0008150",
"GO:0009268",
"GO:0009628",
"GO:0009987",
"GO:0010570",
"GO:0022407",
"GO:0022408",
"GO:0030155",
"GO:0030447",
"GO:0036177",
"GO:0040007",
"GO:0040008",
"GO:0044182",
"GO:0045926",
"GO:0045927",
"GO:0048518",
"GO:0048519"... | [
"GO:0000128",
"GO:0007155",
"GO:0007162",
"GO:0008150",
"GO:0009268",
"GO:0009628",
"GO:0009987",
"GO:0010570",
"GO:0022407",
"GO:0022408",
"GO:0030155",
"GO:0030447",
"GO:0036177",
"GO:0040007",
"GO:0040008",
"GO:0044182",
"GO:0045926",
"GO:0045927",
"GO:0048518",
"GO:0048519"... | [
"GO:0003674",
"GO:0003824",
"GO:0004672",
"GO:0016301",
"GO:0016740",
"GO:0016772",
"GO:0016773",
"GO:0140096"
] | [] | AF-Q9Y7W4-F1-model_v6.pdb | 237561.Q9Y7W4 | [
"Q59T89",
"Q5A5P9",
"Q5ADU9",
"Q5AG95",
"Q5ALX3",
"Q5A4H9",
"A0A1D8PD68",
"Q5A462",
"A0A1D8PUA6",
"Q5AAS1",
"Q5AK73",
"Q5AHH0",
"Q9HF08"
] | [
"IPR008271",
"IPR050108",
"IPR017441",
"IPR011009",
"IPR000719"
] | {"IPR011009": [38, 355], "IPR050108": [42, 355], "IPR000719": [44, 349], "IPR008271": [175, 187], "IPR017441": [50, 73]} | - Bur2p
- Transcription elongation factor SPT5
- DNA-directed RNA polymerase subunit
- Cyclin-like domain-containing protein
- TFIIH complex kinase subunit
- Transcription elongation factor SPT4
- Mediator of RNA polymerase II transcription subunit 1
- CID domain-containing protein
- [RNA-polymerase]-subunit kinase
- R... | - IPR008271: Serine/threonine-protein kinase, active site (active_site) [175-187]
- IPR050108: Cyclin-dependent kinase (family) [42-355]
- IPR017441: Protein kinase, ATP binding site (binding_site) [50-73]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [38-355]
- IPR000719: Protein kinase ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0004672 (protein kinase activity), GO:0004674 (protein seri... |
Q2TBE0 | CWF19-like protein 2 | null | Homo sapiens (Human) | 894 | null | MATSMAAASGRFESAKSIEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKHSKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKAWKVKDEKSGKDDTQIIKRDEWMTVDFMSVKTVSSSSLKAEKETMRKIEQEKNQALEQSKLMERELNPYWKDGGTGLPPEDCSVSSITKVSVVEDGGLSWLRKSYLRMKEQAEKQSRNFEDIVAERYGSMEIFQSKLEDAEKAASTKEDYRRERWRKPTYSDKAQNCQESRESDLVKYGNSSRDRYAT... | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | AF-Q2TBE0-F1-model_v6.pdb | 9606.ENSP00000282251 | [
"Q6P4I0",
"Q9BTK5",
"Q5TH73",
"Q9UDV1",
"Q6IB86",
"Q6FGS0",
"Q6P2Q9",
"Q96DI7",
"Q9Y2Q8",
"D6RC18",
"Q9NV13",
"Q9NYD8",
"Q8TBD2",
"Q5D0D6",
"Q9NQT7",
"Q9H8X8",
"Q9BRX9",
"Q8WUD4",
"Q5BKT2",
"Q9UIS5",
"Q9UPG1",
"Q9ULP3",
"P62318",
"Q99974",
"Q9Y3C6",
"Q9NW64",
"Q9U... | [
"IPR036265",
"IPR006768",
"IPR040194",
"IPR006767"
] | {"IPR036265": [663, 803], "IPR040194": [76, 890], "IPR006768": [664, 786], "IPR006767": [795, 889]} | - Pre-mRNA-processing factor 17
- Pre-mRNA-processing factor 19
- 116 kDa U5 small nuclear ribonucleoprotein component
- Cell division cycle 5-like protein
- Pre-mRNA-splicing factor SYF2
- Peptidyl-prolyl cis-trans isomerase-like 1
- U2 small nuclear ribonucleoprotein A'
- Pre-mRNA-processing-splicing factor 8
- Pleio... | - IPR036265: HIT-like superfamily (homologous_superfamily) [663-803]
- IPR006768: Cwf19-like, C-terminal domain-1 (domain) [664-786]
- IPR040194: Cwf19-like protein (family) [76-890]
- IPR006767: Cwf19-like protein, C-terminal domain-2 (domain) [795-889] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... |
Q54LT7 | Probable cytochrome P450 519E1 | null | Dictyostelium discoideum (Social amoeba) | 506 | Membrane; Single-pass membrane protein | MGIGLIILYLLIGLLAYDFTKKNKKISKNDPKQPLAIPVLGHLHLFGSQPHRSLTELAKKFGGIFTLWMGDERSMVITDPNILRELYVKNHLNFYNRASSESIRIYSGNLVDISFSVGESWKNRRRYVSAALTKTKVLNVITLIEEQANFLINSMQYYAKSGEPFFPHKYYNKYTMNIVMSIGFSKTISENESVEEGPISQLIIPFYNILENLGSGNLGDYVWYTQPFFYFKNKKLEQDTKKVYTFLEEIYNEHIKNLDESNPRDLMDQLIISTGGKEKDMVIHVSTDFLLAGSDTNASTLEWFCIFLANNPEIQKKAYE... | [
"GO:0008150",
"GO:0042221",
"GO:0050896",
"GO:1901698",
"GO:1902351"
] | [
"GO:0008150",
"GO:0042221",
"GO:0050896",
"GO:1901698",
"GO:1902351"
] | [] | [] | AF-Q54LT7-F1-model_v6.pdb | 44689.Q54LT7 | null | [
"IPR017972",
"IPR036396",
"IPR001128",
"IPR002401"
] | {"IPR036396": [16, 506], "IPR001128": [31, 501], "IPR002401": [58, 476], "IPR017972": [446, 455]} | - IPR017972: Cytochrome P450, conserved site (conserved_site) [446-455]
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [16-506]
- IPR001128: Cytochrome P450 (family) [31-501]
- IPR002401: Cytochrome P450, E-class, group I (family) [58-476] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0008395 (steroid hydroxylase activi... | |
Q14T82 | Lauric acid 10-hydroxylase | Cytochrome P450 hydroxylase catalyzing the conversion of decanoate (capric acid) and dodecanoate (lauric acid) to their corresponding omega-hydroxy metabolites, 10-hydroxydecanoate and 12- hydroxydodecanoate, respectively; these hydroxylated components affect plant growth, including reducing root elongation | Petunia hybrida (Petunia) | 573 | Endoplasmic reticulum membrane; Multi-pass membrane protein | MDYVNILLGLFFTWFLVNGLMSLRRRKISKKLPPGPFPLPIIGNLHLLGNHPHKSLAQLAKIHGPIMNLKLGQLITVVISSSVVAREVLQKQDLTFSNRFVPDVVHVRNHSDFSFVWLPVNSRWRTLRKIMNSSIFSGNKLDGNQHLRSKKVQELIDYCQKCAKNGEAVDIGRATFGTTLNLLSNTIFSKDLTNPFSDSAKEFKELVWNIMVEAWKTQFGGLLSFPLRKFDPQGIKRRMTNYFTKFLGLISGLIDERLKERNLRDNANIDVLDALLNISKRTQKRLTGIKSSSCLVSLFPTPFLPFIIICPFLYLLIFHR... | [
"GO:0001676",
"GO:0006082",
"GO:0006629",
"GO:0006631",
"GO:0006690",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0019369",
"GO:0019752",
"GO:0032787",
"GO:0033559",
"GO:0043436",
"GO:0044238",
"GO:0044281",
"GO:0048252",
"GO:0050789",
"GO:0050793",
"GO:0051791",
"GO:0065007"... | [
"GO:0001676",
"GO:0006082",
"GO:0006629",
"GO:0006631",
"GO:0006690",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0019369",
"GO:0019752",
"GO:0032787",
"GO:0033559",
"GO:0043436",
"GO:0044238",
"GO:0044281",
"GO:0048252",
"GO:0050789",
"GO:0050793",
"GO:0051791",
"GO:0065007"... | [
"GO:0003674",
"GO:0003824",
"GO:0004497",
"GO:0016491",
"GO:0016705",
"GO:0016712",
"GO:0120250",
"GO:0120319",
"GO:0120502"
] | [] | AF-Q14T82-F1-model_v6.pdb | null | null | [
"IPR017972",
"IPR036396",
"IPR001128",
"IPR002401"
] | {"IPR036396": [21, 572], "IPR001128": [33, 558], "IPR002401": [60, 539], "IPR017972": [509, 518]} | - IPR017972: Cytochrome P450, conserved site (conserved_site) [509-518]
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [21-572]
- IPR001128: Cytochrome P450 (family) [33-558]
- IPR002401: Cytochrome P450, E-class, group I (family) [60-539] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0004497 (monooxygenase activity), GO:0016709 (oxidoreductase activity, a... | |
P38505 | Calcium-binding protein 1 | Calcium-binding protein which probably acts as a calcium sensor and modulator, contributing to cellular Ca(2+)-mediated signaling. Activates endogenous kinase(s) in a Ca(2+)-dependent manner. Plays a role in regulating actin cytoskeleton dynamics. Regulates the association of actin filaments in a bundle but not actin p... | Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM) | 134 | Cytoplasm. Cell projection, phagocytic cup. Cell projection, pseudopodium. Note=During host erythrocyte phagocytosis, co-localizes with F-actin to the phagocytic cup. Leaves the phagocytic cup before the formation of phagosomes. Co-localizes with FAK in the pseudopodium | MAEALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFYGSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKADANGDGYITLEEFLEFSL | [
"GO:0001932",
"GO:0008150",
"GO:0019222",
"GO:0030100",
"GO:0031399",
"GO:0032231",
"GO:0032879",
"GO:0032956",
"GO:0032970",
"GO:0033043",
"GO:0042325",
"GO:0043549",
"GO:0044087",
"GO:0045807",
"GO:0045859",
"GO:0048518",
"GO:0048522",
"GO:0048548",
"GO:0048549",
"GO:0050764"... | [
"GO:0001932",
"GO:0008150",
"GO:0019222",
"GO:0030100",
"GO:0031399",
"GO:0032231",
"GO:0032879",
"GO:0032956",
"GO:0032970",
"GO:0033043",
"GO:0042325",
"GO:0043549",
"GO:0044087",
"GO:0045807",
"GO:0045859",
"GO:0048518",
"GO:0048522",
"GO:0048548",
"GO:0048549",
"GO:0050764"... | [
"GO:0003674",
"GO:0003779",
"GO:0003785",
"GO:0005488",
"GO:0005509",
"GO:0005515",
"GO:0008092",
"GO:0036094",
"GO:0043167",
"GO:0043169",
"GO:0044877",
"GO:0046872",
"GO:0051015"
] | [
"GO:0001891",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005886",
"GO:0016020",
"GO:0031143",
"GO:0042995",
"GO:0071944",
"GO:0110165",
"GO:0120025"
] | AF-P38505-F1-model_v6.pdb | null | null | [
"IPR002048",
"IPR039647",
"IPR011992",
"IPR018247"
] | {"IPR011992": [4, 131], "IPR039647": [3, 60], "IPR002048": [1, 134], "IPR018247": [10, 129]} | - IPR002048: EF-hand domain (domain) [1-134]
- IPR039647: EF-hand domain pair protein CML-like (family) [3-60]
- IPR011992: EF-hand domain pair (homologous_superfamily) [4-131]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [10-129] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of ... | |
Q5ADW3 | Cullin-associated NEDD8-dissociated protein 1 | Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate- recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor (Probable) | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,195 | null | MHDINFNILKDRAMDVDPDIRFMALEDLRKFLQDESAASTRTTLNQSLENFFPILLNMLNDQNPDVQTQAIKSFEPMVKYLSNETFSKLVKKLFALVQQNSSSTGNVTGMKSFTVSVPNIALRSLFAQSNSRDKSEFVSDKLSNSNYRFDPHLARYIMDYLIPQIVGNPVTIDSIELLIDLVTEIGYVLTQDELLNLSLYLTKVALTETGLIGKKSMVALERVVALVRTEVVIDKLLAQINQSIEPTKLFVIFQLYSVCLKRGIKPNSIDTIYNTITSNLNIEATEEEDDDDLDFDNLVKENSLKDEALTTLIDLVSQHF... | [
"GO:0006508",
"GO:0006511",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009057",
"GO:0009987",
"GO:0010498",
"GO:0019538",
"GO:0019941",
"GO:0030163",
"GO:0031146",
"GO:0043161",
"GO:0043170",
"GO:0043632",
"GO:0044238",
"GO:0051603",
"GO:0000151",
"GO:0005575",
"GO:0019005"... | [
"GO:0006508",
"GO:0006511",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009057",
"GO:0009987",
"GO:0010498",
"GO:0019538",
"GO:0019941",
"GO:0030163",
"GO:0031146",
"GO:0043161",
"GO:0043170",
"GO:0043632",
"GO:0044238",
"GO:0051603"
] | [] | [
"GO:0000151",
"GO:0005575",
"GO:0019005",
"GO:0031461",
"GO:0032991",
"GO:0140535",
"GO:1902494",
"GO:1990234"
] | AF-Q5ADW3-F1-model_v6.pdb | 237561.Q5ADW3 | [
"Q5ADL9",
"Q59RB3",
"Q59WE2",
"A0A1D8PJL5",
"A0A1D8PRP1",
"Q59PI9",
"A0A1D8PJP6",
"A0A1D8PP13",
"Q5A7Q5",
"A0A1D8PDR1",
"Q5AJB7"
] | [
"IPR016024",
"IPR011989",
"IPR039852",
"IPR013932",
"IPR021133",
"IPR000357"
] | {"IPR011989": [2, 1178], "IPR016024": [5, 1188], "IPR039852": [4, 1185], "IPR013932": [1003, 1181], "IPR000357": [51, 80], "IPR021133": [51, 89]} | - SCF ubiquitin ligase complex subunit
- Cullin
- Cullin
- Cullin
- COP9 signalosome complex subunit 5
- E3 ubiquitin ligase complex SCF subunit
- NEDD8 family protein
- Elongin-C
- NEDD8-conjugating enzyme UBC12
- Defective in cullin neddylation protein 1 | - IPR016024: Armadillo-type fold (homologous_superfamily) [5-1188]
- IPR011989: Armadillo-like helical (homologous_superfamily) [2-1178]
- IPR039852: Cullin-associated NEDD8-dissociated protein 1/2 (family) [4-1185]
- IPR013932: TATA-binding protein interacting (TIP20) (domain) [1003-1181]
- IPR021133: HEAT, type 2 (re... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0009605 (response to external stimulus), GO:0051716 (cellular r... |
Q14444 | Caprin-1 | mRNA-binding protein that acts as a regulator of mRNAs transport, translation and/or stability, and which is involved in neurogenesis, synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Plays an essential role in cytoplasmic stress granule formation. Acts as an mRNA regulator by... | Homo sapiens (Human) | 709 | Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cytoplasm, cytosol. Cell projection, dendrite. Cell projection, lamellipodium. Note=Mediates formation and localizes to cytoplasmic ribonucleoprotein membraneless compartments. Associated with RNA granules. At the leading edge of migrating fibroblasts, colocalizes with ... | MPSATSHSGSGSKSSGPPPPSGSSGSEAAAGAGAAAPASQHPATGTGAVQTEAMKQILGVIDKKLRNLEKKKGKLDDYQERMNKGERLNQDQLDAVSKYQEVTNNLEFAKELQRSFMALSQDIQKTIKKTARREQLMREEAEQKRLKTVLELQYVLDKLGDDEVRTDLKQGLNGVPILSEEELSLLDEFYKLVDPERDMSLRLNEQYEHASIHLWDLLEGKEKPVCGTTYKVLKEIVERVFQSNYFDSTHNHQNGLCEEEEAASAPAVEDQVPEAEPEPAEEYTEQSEVESTEYVNRQFMAETQFTSGEKEQVDEWTVET... | [
"GO:0000288",
"GO:0000290",
"GO:0000956",
"GO:0006139",
"GO:0006401",
"GO:0006402",
"GO:0006417",
"GO:0006446",
"GO:0006996",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009057",
"GO:0009889",
"GO:0009890",
"GO:0009892",
"GO:0009893",
"GO:0009894",
"GO:0009896",
"GO:0009987"... | [
"GO:0000288",
"GO:0000290",
"GO:0000956",
"GO:0006139",
"GO:0006401",
"GO:0006402",
"GO:0006417",
"GO:0006446",
"GO:0006996",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009057",
"GO:0009889",
"GO:0009890",
"GO:0009892",
"GO:0009893",
"GO:0009894",
"GO:0009896",
"GO:0009987"... | [] | [] | AF-Q14444-F1-model_v6.pdb | 9606.ENSP00000340329 | [
"Q9Y2S4",
"Q53HJ1",
"Q99700",
"Q8N6R8",
"Q9H4A8",
"Q96B58",
"Q99556",
"Q5D048",
"Q9NVF2",
"Q8N102",
"Q9NVB6",
"Q99054",
"Q9UPA1",
"Q93004",
"Q61516",
"Q8WUM2",
"Q9UMF9",
"Q9NSL7",
"Q9UDL5",
"Q5HYE9",
"O15536",
"Q92900",
"Q01085",
"Q96E95",
"Q5FVF0",
"Q9UGL5",
"Q96... | [
"IPR028816",
"IPR041637",
"IPR022070"
] | {"IPR028816": [33, 695], "IPR041637": [132, 247], "IPR022070": [359, 685]} | - Ras GTPase-activating protein-binding protein 1
- Ras GTPase-activating protein-binding protein 2
- Fragile X messenger ribonucleoprotein 1
- RNA cytidine acetyltransferase
- Ubiquitin carboxyl-terminal hydrolase 10
- RNA-binding protein FXR2
- RNA-binding protein FXR1
- Nucleolysin TIAR
- Cytotoxic granule associate... | - IPR028816: Caprin (family) [33-695]
- IPR041637: Caprin-1 dimerization domain (domain) [132-247]
- IPR022070: Cytoplasmic activation/proliferation-associated protein-1 C term (domain) [359-685] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding)
Biological Process (BP): GO:0008150 (biological process), GO... |
Q1K615 | Beta-apo-4'-carotenal oxygenase | Beta-apo-4'-carotenal oxygenase involved in the last step of synthesis of neurosporaxanthin, a carboxylic apocarotenoid acting as an essential protective pigment and leading to orange pigmentation. Converts the aldehyde beta-apo-4'-carotenal into neurosporaxanthin. Neurosporaxanthin is synthesized from geranyl-geranyl ... | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / | 533 | null | MAASKVEIAPFEVTPLDAIPAVCSTARATFASHKTKNLQWRLVQLRKLYWALDDFKASLMAALQQDLRKGGYESDFTEVDWVKNDCLHMINNLETFAKTEKLKDLPVTYSMMNFRVKKEPLGTVLIIGPYNFPIQLVLAPLVGAIGAGCTAVIKPSELTPACAMAMKEMIESRLDRDAFAVVNGGVPETNALMEEKWDKIMFTGSAQVGSIIARKAAETLTPVCLELGGRNPAFVTKKANLALAARRLMWGKVLNAGQVCMSHNYVLVDKDVADTFIEFLKIAYKDMFPNGAKASPDLSRIVNARHFNRIKKMLDETKGK... | [
"GO:0006629",
"GO:0006720",
"GO:0006721",
"GO:0008150",
"GO:0008152",
"GO:0008299",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016109",
"GO:0016114",
"GO:0016116",
"GO:0016117",
"GO:0042440",
"GO:0044238",
"GO:0046148",
"GO:0003674",
"GO:0003824",
"GO:0004029",
"GO:0004030"... | [
"GO:0006629",
"GO:0006720",
"GO:0006721",
"GO:0008150",
"GO:0008152",
"GO:0008299",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016109",
"GO:0016114",
"GO:0016116",
"GO:0016117",
"GO:0042440",
"GO:0044238",
"GO:0046148"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004029",
"GO:0004030",
"GO:0016491",
"GO:0016620",
"GO:0016903"
] | [] | AF-Q1K615-F1-model_v6.pdb | 367110.Q1K615 | [
"Q1K773",
"Q7SAQ2",
"Q7SBJ5",
"V5IP16",
"Q7RVN3",
"A7UXI1",
"A7UWE4"
] | [
"IPR012394",
"IPR016162",
"IPR016161",
"IPR016163",
"IPR015590"
] | {"IPR016161": [21, 464], "IPR016162": [27, 444], "IPR016163": [229, 426], "IPR012394": [17, 486], "IPR015590": [17, 446]} | - Carotenoid dioxygenase
- Peroxisomal membrane protein
- ATPase family AAA domain-containing protein 1
- Peroxin
- Hsc70 cochaperone
- Mitochondrial fission 1 protein
- Bifunctional lycopene cyclase/phytoene synthase | - IPR012394: Aldehyde dehydrogenase NAD(P)-dependent (family) [17-486]
- IPR016162: Aldehyde dehydrogenase, N-terminal (homologous_superfamily) [27-444]
- IPR016161: Aldehyde/histidinol dehydrogenase (homologous_superfamily) [21-464]
- IPR016163: Aldehyde dehydrogenase, C-terminal (homologous_superfamily) [229-426]
- I... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016903 (oxidoreductase activity, acting on the aldehyde or oxo group of donors), GO:0016620 (oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as accepto... |
Q59VH7 | Secreted aspartic protease 7 | Secreted aspartic peptidases (SAPs) are a group of ten acidic hydrolases considered as key virulence factors (By similarity). These enzymes supply the fungus with nutrient amino acids as well as are able to degrade the selected host's proteins involved in the immune defense (By similarity) | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 588 | Secreted | MQRVLELLLLSSTALAVIGDGFIALPVHKLQAGEGSAHFPNRLPIFDVVNGVAKSVEDDVNQIIQPIFGNGIFSGGSIQGTHSGNGHSVKYEVSLPSSSSQKGSNGPSSTDNKDTDPSKTGFSLDDLMNSIPTDFWNLIGLNKAPTSSDNGSKDADFTPSAVSQVEQPTSKSVESTAPGPASSASSSSSSEAASSSQPSEDSQPSSSANKKTGAFFLSLDNTQTLYTATLKVGSPAQEVQVMIDTGSSDLWFISSGNSQCKVNGGSIDCDKYGVFDKSKSSTWHDNKTDYSISYYDGDKASGTMGQDNITFADGFSIENA... | [
"GO:0006508",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0019538",
"GO:0043170",
"GO:0044238",
"GO:0003674",
"GO:0003824",
"GO:0004175",
"GO:0004190",
"GO:0008233",
"GO:0016787",
"GO:0070001",
"GO:0140096",
"GO:0005575",
"GO:0005576",
"GO:0031982",
"GO:0043226",
"GO:0043227"... | [
"GO:0006508",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0019538",
"GO:0043170",
"GO:0044238"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004175",
"GO:0004190",
"GO:0008233",
"GO:0016787",
"GO:0070001",
"GO:0140096"
] | [
"GO:0005575",
"GO:0005576",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043230",
"GO:0065010",
"GO:0110165",
"GO:1903561"
] | AF-Q59VH7-F1-model_v6.pdb | 237561.Q59VH7 | null | [
"IPR001969",
"IPR033876",
"IPR001461",
"IPR033121",
"IPR021109"
] | {"IPR021109": [211, 587], "IPR001461": [186, 575], "IPR033876": [224, 576], "IPR033121": [226, 576], "IPR001969": [241, 252]} | - IPR001969: Aspartic peptidase, active site (active_site) [241-252]
- IPR033876: Secreted aspartic endopeptidase (domain) [224-576]
- IPR001461: Aspartic peptidase A1 (family) [186-575]
- IPR033121: Peptidase family A1 domain (domain) [226-576]
- IPR021109: Aspartic peptidase domain superfamily (homologous_superfamily... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity), GO:0070001 (aspartic-type peptidase activity), GO:0004190 (aspartic-type... | |
A0A2H1A5W4 | Cell wall integrity transcriptional regulator CAS5 | Transcription factor involved in the cell wall damage response. Required for expression of numerous cell wall biosynthesis inhibitor caspofungin-responsive genes. Plays a key role in adherence, hyphal development, and virulence (By similarity) | Candidozyma auris (Yeast) (Candida auris) | 679 | Nucleus. Cytoplasm. Note=Localizes to the cytoplasm under basal conditions and translocates to the nucleus during caspofungin treatment | MENYLMSSPSQHHHPHQQPHQQHNPYANSDTLTNLPNLENDLDFSDSEVVPPSKDYQGSPNVYDGLDFSTDMATDFVYDSTLEFDLDDHKHMPDPAEMGHSKHFSVDRPLSAPFYLSQNSRTNFNHSRNISLDDTAYKRSFHKHSASLVSNAAEPPSGTFAHSHSSNTLQSSSDSMPQLSSSVSNPSLLDSPHSAMQTATPGRRHKSSSVSSHTNLYTTPLRGGTHVSPLTHTKVGKTPIGKTHRRNRSRASLEPSSAHLLATVANMKGTSNASNLALSSAQTPSGHLTASTSQHFHGINLSEANPFHNEFVSPGVGSGH... | [
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0031505",
"GO:0045229",
"GO:0071554",
"GO:0071555",
"GO:0071840",
"GO:0071852",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | [
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0031505",
"GO:0045229",
"GO:0071554",
"GO:0071555",
"GO:0071840",
"GO:0071852"
] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-A0A2H1A5W4-F1-model_v6.pdb | 498019.A0A2H1A5W4 | null | [
"IPR013087",
"IPR036236"
] | {"IPR036236": [631, 677], "IPR013087": [622, 675]} | - IPR013087: Zinc finger C2H2-type (domain) [622-675]
- IPR036236: Zinc finger C2H2 superfamily (homologous_superfamily) [631-677] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0040007 (growth), GO:0009987 (cellular process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interactio... | |
P70343 | Caspase-4 | Inflammatory caspase that acts as the effector of the non- canonical inflammasome by mediating lipopolysaccharide (LPS)-induced pyroptosis. Also indirectly activates the NLRP3 and NLRP6 inflammasomes. Acts as a thiol protease that cleaves a tetrapeptide after an Asp residue at position P1: catalyzes cleavage of CGAS an... | Mus musculus (Mouse) | 373 | Cytoplasm, cytosol. Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion. Inflammasome. Secreted. Note=Predominantly localizes to the endoplasmic reticulum (ER). Association with the ER membrane requires TMEM214. Released in the extracellular milieu by keratinocytes fo... | MAENKHPDKPLKVLEQLGKEVLTEYLEKLVQSNVLKLKEEDKQKFNNAERSDKRWVFVDAMKKKHSKVGEMLLQTFFSVDPGSHHGEANLEMEEPEESLNTLKLCSPEEFTRLCREKTQEIYPIKEANGRTRKALIICNTEFKHLSLRYGANFDIIGMKGLLEDLGYDVVVKEELTAEGMESEMKDFAALSEHQTSDSTFLVLMSHGTLHGICGTMHSEKTPDVLQYDTIYQIFNNCHCPGLRDKPKVIIVQACRGGNSGEMWIRESSKPQLCRGVDLPRNMEADAVKLSHVEKDFIAFYSTTPHHLSYRDKTGGSYFIT... | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0032991",
"GO:0110165",
"GO:0160074"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0032991",
"GO:0110165",
"GO:0160074"
] | AF-P70343-F1-model_v6.pdb | 10090.ENSMUSP00000027012 | [
"Q91WS2",
"Q3TT82",
"Q9EPB4",
"T1W2H6",
"Q8BS50",
"Q9R030",
"Q8VEC5",
"Q9R017",
"Q3UP24",
"Q3UEM3",
"Q9Z2D3",
"Q9R029",
"Q67EY4",
"Q9D8T2",
"Q8BN26",
"O88879",
"Q9D2Y4",
"Q91VF3",
"Q9JIB6",
"Q91VJ1",
"Q62167",
"Q4PLS0",
"Q2LKV8",
"Q2M4J6",
"P70380",
"Q6UTW9",
"Q6U... | [
"IPR002398",
"IPR033139",
"IPR001309",
"IPR029030",
"IPR015917",
"IPR011600",
"IPR001315",
"IPR011029",
"IPR016129",
"IPR002138"
] | {"IPR011029": [4, 85], "IPR029030": [109, 372], "IPR002398": [1, 373], "IPR001315": [1, 92], "IPR015917": [121, 371], "IPR001309": [130, 258], "IPR011600": [131, 368], "IPR002138": [286, 371], "IPR016129": [193, 207], "IPR033139": [245, 256]} | - Gasdermin-D
- NACHT, LRR and PYD domains-containing protein 1a
- Caspase-1
- Apoptosis-associated speck-like protein containing a CARD
- NACHT, LRR and PYD domains-containing protein 3
- NLR family CARD domain-containing protein 4
- Interferon-inducible protein AIM2
- NACHT, LRR and PYD domains-containing protein 6
-... | - IPR002398: Peptidase C14 family (family) [1-373]
- IPR033139: Peptidase family C14A, cysteine active site (active_site) [245-256]
- IPR001309: Peptidase C14, p20 domain (domain) [130-258]
- IPR029030: Caspase-like domain superfamily (homologous_superfamily) [109-372]
- IPR015917: Peptidase C14A, caspase catalytic dom... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0008234 (cysteine-type peptidase activity), GO:0004175... |
Q567I9 | Cytochrome b5 domain-containing protein 1 | Radial spoke stalk protein that binds heme under oxidizing conditions (Probable). Required for the coordinated beating of multiple cilia maybe by functioning in a redox signaling pathway | Danio rerio (Zebrafish) (Brachydanio rerio) | 214 | Cytoplasm, cytoskeleton, cilium axoneme. Note=Localizes to the radial spoke stalk | MRRSKYFTPNEVSLHNTINDIWVSYLGKVYDLTPLLEAYKGDVLLKPIIECAGKDISHWFDPKTKDILTHVDPLTGCIKYYTPRGRFIHIPPPCPRTDWANNFGKPWWKDNRYEVGLLSAKTRWIRIINTLTSQEQKLEVCSEESLDEILHRYLFYNSHAASYTWKLSGINLDMSKTLSENGIPEEDEFYCGSPDCNLFSPSICLYFNDDLTEL | [
"GO:0003341",
"GO:0003352",
"GO:0003356",
"GO:0007017",
"GO:0007018",
"GO:0008150",
"GO:0009987",
"GO:0032886",
"GO:0050789",
"GO:0050794",
"GO:0060632",
"GO:0065007"
] | [
"GO:0003341",
"GO:0003352",
"GO:0003356",
"GO:0007017",
"GO:0007018",
"GO:0008150",
"GO:0009987",
"GO:0032886",
"GO:0050789",
"GO:0050794",
"GO:0060632",
"GO:0065007"
] | [] | [] | AF-Q567I9-F1-model_v6.pdb | 7955.ENSDARP00000072883 | [
"F1RC30",
"F1QGB9",
"F1QTK3",
"F1QV44",
"F1QWI3",
"F1Q6H8",
"A0A0R4IKF7",
"F1QUA2",
"Q502I6"
] | [
"IPR052320",
"IPR036400",
"IPR001199"
] | {"IPR036400": [1, 99], "IPR052320": [2, 213], "IPR001199": [4, 79]} | - Intelectin 2
- Cilia and flagella-associated protein 58
- Cytochrome b5 reductase 4
- Axonemal dynein light intermediate polypeptide 1
- Sulfite oxidase, mitochondrial | - IPR052320: Cytochrome b5 domain-containing (family) [2-213]
- IPR036400: Cytochrome b5-like heme/steroid binding domain superfamily (homologous_superfamily) [1-99]
- IPR001199: Cytochrome b5-like heme/steroid binding domain (domain) [4-79] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0016491 (oxidoreductase activity), GO:0003676 (nucleic acid binding), GO:0016705 (oxidoreductase activity, acting ... |
Q5A1E3 | Transcriptional regulator CBF1 | Transcription factor that binds ribosomal protein gene promoters and rDNA locus with TBF1. Necessary for the expression of genes involved in assimilation of inorganic sulfate. Also required for the expression of respiratory genes and glycolytic genes. Does not bind to centromeres and is not necessary for efficient chro... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 251 | Nucleus | MVKSHKRTLEKDEEHQEKKKANKISKDDMEIDAELLTQQASDSAHTDTATAAVAAVNNEQGKELEQTESSTNQTSALDKDDKETKDNLNPREETQSSHQEIDIPKDQLTNQQNLADQHQQYQYHQQLAQTNFKTEPTNSAKPPHGSEEWHRQRRENHKEVERKRRESINTGIRELARLIPTTDTNKAQILQRAVEYIKRLKENENNNIEKWTLEKLLTEQAVSELSASNEKLKHELESAYREIEQLKRGKK | [
"GO:0000070",
"GO:0000096",
"GO:0000097",
"GO:0000103",
"GO:0000278",
"GO:0000280",
"GO:0000819",
"GO:0006082",
"GO:0006139",
"GO:0006351",
"GO:0006520",
"GO:0006555",
"GO:0006790",
"GO:0006996",
"GO:0007049",
"GO:0007059",
"GO:0008150",
"GO:0008152",
"GO:0008652",
"GO:0009058"... | [
"GO:0000070",
"GO:0000096",
"GO:0000097",
"GO:0000103",
"GO:0000278",
"GO:0000280",
"GO:0000819",
"GO:0006082",
"GO:0006139",
"GO:0006351",
"GO:0006520",
"GO:0006555",
"GO:0006790",
"GO:0006996",
"GO:0007049",
"GO:0007059",
"GO:0008150",
"GO:0008152",
"GO:0008652",
"GO:0009058"... | [
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003690",
"GO:0003700",
"GO:0005488",
"GO:0019237",
"GO:0043565",
"GO:0140110",
"GO:1990837"
] | [
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005694",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q5A1E3-F1-model_v6.pdb | 237561.Q5A1E3 | [
"Q59LN9",
"A0A1D8PQN4",
"Q5A5T7"
] | [
"IPR036638",
"IPR011598",
"IPR047206"
] | {"IPR036638": [143, 210], "IPR047206": [147, 233], "IPR011598": [152, 206]} | - Met28p
- Met4p
- Histone H3-like centromeric protein CSE4 | - IPR036638: Helix-loop-helix DNA-binding domain superfamily (homologous_superfamily) [143-210]
- IPR011598: Myc-type, basic helix-loop-helix (bHLH) domain (domain) [152-206]
- IPR047206: Centromere-binding protein 1-like, bHLHzip domain (domain) [147-233] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:0097159 (organic cyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (... |
P31225 | Corticosteroid-binding protein | May be a flavoprotein with enzymatic activity | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 489 | null | MSRTKSTKVLIIGAGVSGLKAAETILSKSFLTGDDVLVVEAQNRIGGRLKTTDTSQSKLGINYDLGASWFHDSLNNIVLNHMINDGLLDDEKDVYFDDKDLKTFSSTGEVPIVDKKLNRVLEDIEKYIQLYFNRNLGVPDLSLRDIVAQYFEKYNRLITEEQREYCGRMMRYLEFWFGISWDRISGKYAVTTHQGRNLLNKKGYGYLVESLAKRIPESSLLLEEPVNKIIRNNKDAGKRVLVETINGLQIFCDYLIVTVPQSILSLEESSPYSIKWEPKLPQRLVESINSIHFGALGKVIFEFDRIFWDNSKDRFQIIAD... | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | [] | [] | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | AF-P31225-F1-model_v6.pdb | 237561.P31225 | [
"Q5AH20",
"A0A1D8PLL0",
"Q59KV5",
"A0A1D8PLN0",
"A0A1D8PPP3",
"Q59Z50",
"Q5AL17",
"Q5ABD8",
"Q5A0M7",
"A0A1D8PSW6",
"Q5AMQ8",
"Q5ANN8",
"A0A1D8PC76",
"A0A1D8PGT5"
] | [
"IPR036188",
"IPR002937",
"IPR050281"
] | {"IPR036188": [4, 475], "IPR050281": [7, 477], "IPR002937": [16, 474]} | - Ornithine decarboxylase
- Spermidine synthase
- Aldehyde dehydrogenase domain-containing protein
- Aldehyde dehydrogenase
- Agmatinase
- Afp99p
- Spermine synthase
- Amine oxidase
- Amine oxidase
- Polyamine oxidase | - IPR036188: FAD/NAD(P)-binding domain superfamily (homologous_superfamily) [4-475]
- IPR002937: Amine oxidase (domain) [16-474]
- IPR050281: Flavin monoamine oxidase and related enzymes (family) [7-477] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:0008289 (lipid binding), GO:0005496 (steroid binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009056 (catabolic process), GO:0071704 (org... |
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