protein_id stringlengths 6 10 | protein_names stringlengths 2 1.26k | protein_function stringlengths 9 5.75k ⌀ | organism stringclasses 589
values | length float64 11 16k | subcellular_location stringlengths 7 6.16k ⌀ | sequence stringlengths 11 16k | go_ids listlengths 2 494 | go_bp listlengths 0 437 ⌀ | go_mf listlengths 0 59 ⌀ | go_cc listlengths 0 67 ⌀ | structure_path stringlengths 25 29 ⌀ | string_id stringlengths 10 27 ⌀ | interaction_partners listlengths 1 668 ⌀ | interpro_ids listlengths 1 20 ⌀ | interpro_location stringlengths 3 529 | ppi_formatted stringlengths 0 811 | interpro_formatted stringlengths 0 1.79k | go_pred stringlengths 369 15k |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
O28126 | CCA-adding enzyme | Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is require... | Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC | 437 | null | MKVEEILEKALELVIPDEEEVRKGREAEEELRRRLDELGVEYVFVGSYARNTWLKGSLEIDVFLLFPEEFSKEELRERGLEIGKAVLDSYEIRYAEHPYVHGVVKGVEVDVVPCYKLKEPKNIKSAVDRTPFHHKWLEGRIKGKENEVRLLKGFLKANGIYGAEYKVRGFSGYLCELLIVFYGSFLETVKNARRWTRRTVIDVAKGEVRKGEEFFVVDPVDEKRNVAANLSLDNLARFVHLCREFMEAPSLGFFKPKHPLEIEPERLRKIVEERGTAVFAVKFRKPDIVDDNLYPQLERASRKIFEFLERENFMPLRSAF... | [
"GO:0006139",
"GO:0006399",
"GO:0006401",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009057",
"GO:0009987",
"GO:0016070",
"GO:0016078",
"GO:0034655",
"GO:0043170",
"GO:0044238",
"GO:0071025",
"GO:0090304",
"GO:0106354",
"GO:0141188",
"GO:0003674",
"GO:0003824",
"GO:0016740"... | [
"GO:0006139",
"GO:0006399",
"GO:0006401",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009057",
"GO:0009987",
"GO:0016070",
"GO:0016078",
"GO:0034655",
"GO:0043170",
"GO:0044238",
"GO:0071025",
"GO:0090304",
"GO:0106354",
"GO:0141188"
] | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016772",
"GO:0016779",
"GO:0070567",
"GO:0140098",
"GO:0140101",
"GO:0140640",
"GO:0160016"
] | [] | AF-O28126-F1-model_v6.pdb | 224325.AF_2156 | [
"O29362",
"O28125",
"O28127",
"O28124",
"O30024",
"O28122",
"O28128",
"O28123",
"O29719",
"O29698",
"O28831"
] | [
"IPR006116",
"IPR008229",
"IPR015329",
"IPR043519",
"IPR048833",
"IPR002934",
"IPR011068",
"IPR042090"
] | {"IPR043519": [1, 143], "IPR042090": [10, 255], "IPR011068": [241, 434], "IPR008229": [1, 437], "IPR002934": [27, 133], "IPR006116": [38, 137], "IPR015329": [146, 255], "IPR048833": [274, 417]} | - tRNA-splicing endonuclease
- RNA 2',3'-cyclic phosphodiesterase
- Metallo-beta-lactamase domain-containing protein
- UPF0179 protein AF_2154
- Molybdenum cofactor biosynthesis protein (MoeB)
- Thiamine biosynthesis protein (ThiF)
- Uncharacterized protein
- Uncharacterized protein AF_2158
- Uncharacterized protein AF... | - IPR006116: 2-5OAS/ClassI-CCAase, nucleotidyltransferase domain (domain) [38-137]
- IPR008229: tRNA nucleotidyltransferase, archaea (family) [1-437]
- IPR015329: tRNA nucleotidyltransferase, substrate binding (domain) [146-255]
- IPR043519: Nucleotidyltransferase superfamily (homologous_superfamily) [1-143]
- IPR04883... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016779 (nucleotidyltransferase activity), GO:0070566 (adenylyltransferase activity)
Biological Process (BP): GO:... |
P77978 | CCA-adding enzyme | Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. tRNA 3'-terminal CCA addition is require... | Saccharolobus shibatae (strain ATCC 51178 / DSM 5389 / JCM 8931 / NBRC | 412 | null | MIEEEVLKIIKPTEEDKKGIEKVLEIIRERLNKLDFEVEGSFRKGTWLRQDTDVDVFVFYPKDVGKEYLERNALNDIINRIKDLDYTLAYAEHPYVIVNINNVEVDIVPALRVESGDRAITAVDRTPFHTKYVTSHLDERGKDEVRLLKRFMKGIGVYGAELKVQGFSGYATELLVIYYGSFRKVLEAASKWKHPIKIELTKPMRAFSEPLIIPDPVDPRRNVTAAVSLKNIATFSVAAKYYLKNPSMEFFFPSKKVEEKIKGDVLILRLNLDEKSSEDIIWGQIKRSVNKIERALKQSGFRVIDIQAWGDTSNIVIAVQ... | [
"GO:0006139",
"GO:0006399",
"GO:0006401",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009057",
"GO:0009987",
"GO:0016070",
"GO:0016078",
"GO:0034655",
"GO:0043170",
"GO:0044238",
"GO:0071025",
"GO:0090304",
"GO:0106354",
"GO:0141188",
"GO:0003674",
"GO:0003824",
"GO:0016740"... | [
"GO:0006139",
"GO:0006399",
"GO:0006401",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009057",
"GO:0009987",
"GO:0016070",
"GO:0016078",
"GO:0034655",
"GO:0043170",
"GO:0044238",
"GO:0071025",
"GO:0090304",
"GO:0106354",
"GO:0141188"
] | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016772",
"GO:0016779",
"GO:0070567",
"GO:0140098",
"GO:0140101",
"GO:0140640",
"GO:0160016"
] | [] | AF-P77978-F1-model_v6.pdb | null | null | [
"IPR006116",
"IPR008229",
"IPR015329",
"IPR043519",
"IPR048833",
"IPR002934",
"IPR011068",
"IPR042090"
] | {"IPR043519": [4, 182], "IPR042090": [6, 252], "IPR011068": [238, 411], "IPR008229": [1, 412], "IPR006116": [12, 136], "IPR002934": [20, 129], "IPR015329": [143, 252], "IPR048833": [275, 380]} | - IPR006116: 2-5OAS/ClassI-CCAase, nucleotidyltransferase domain (domain) [12-136]
- IPR008229: tRNA nucleotidyltransferase, archaea (family) [1-412]
- IPR015329: tRNA nucleotidyltransferase, substrate binding (domain) [143-252]
- IPR043519: Nucleotidyltransferase superfamily (homologous_superfamily) [4-182]
- IPR04883... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0016740 (transferase activity), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohy... | |
Q8WUD4 | Coiled-coil domain-containing protein 12 | null | Homo sapiens (Human) | 166 | null | MEATTAGVGRLEEEALRRKERLKALREKTGRKDKEDGEPKTKHLREEEEEGEKHRELRLRNYVPEDEDLKKRRVPQAKPVAVEEKVKEQLEAAKPEPVIEEVDLANLAPRKPDWDLKRDVAKKLEKLKKRTQRAIAELIRERLKGQEDSLASAVDAATEQKTCDSD | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | AF-Q8WUD4-F1-model_v6.pdb | 9606.ENSP00000292314 | [
"Q9BUR0",
"Q9UPG1",
"Q86XM8",
"Q9UMS4",
"Q96QC1",
"Q9BQA8",
"Q96FM9",
"Q86V81",
"Q96EM3",
"Q9BTK5",
"O15541",
"Q86TG6",
"Q9NYD8",
"Q9H2H8",
"Q71V76",
"Q9NV13",
"Q9HCG8",
"Q96A18",
"Q8IYB3",
"Q9Y3C6",
"Q53Y61",
"Q99974",
"Q9NW16",
"Q8TAG2",
"Q96MI1",
"Q59EA1",
"Q9U... | [
"IPR013169"
] | {"IPR013169": [1, 166]} | - Pre-mRNA-processing factor 17
- Crooked neck-like protein 1
- Pre-mRNA-processing factor 19
- Cell division cycle 5-like protein
- 116 kDa U5 small nuclear ribonucleoprotein component
- Pre-mRNA-splicing factor SYF2
- Peptidyl-prolyl cis-trans isomerase-like 1
- Transcription elongation regulator 1
- Serine/arginine ... | - IPR013169: mRNA splicing factor Cwf18-like (family) [1-166] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... |
Q96HJ3 | Coiled-coil domain-containing protein 34 | Involved in spermatogenesis. Has a probable role in anterograde intraflagellar transport which is essential for the formation of sperm flagella | Homo sapiens (Human) | 373 | Cell projection, cilium, flagellum. Note=Mainly located in the mid-piece of sperm flagella | MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCSNSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAKSYGYANGKLTGFYSGNSYPEPAFYNPIP... | [
"GO:0003006",
"GO:0007276",
"GO:0007283",
"GO:0008150",
"GO:0019953",
"GO:0022414",
"GO:0032502",
"GO:0048232",
"GO:0048609",
"GO:0005575",
"GO:0005929",
"GO:0031514",
"GO:0036126",
"GO:0042995",
"GO:0043226",
"GO:0043227",
"GO:0097225",
"GO:0097729",
"GO:0110165",
"GO:0120025"... | [
"GO:0003006",
"GO:0007276",
"GO:0007283",
"GO:0008150",
"GO:0019953",
"GO:0022414",
"GO:0032502",
"GO:0048232",
"GO:0048609"
] | [] | [
"GO:0005575",
"GO:0005929",
"GO:0031514",
"GO:0036126",
"GO:0042995",
"GO:0043226",
"GO:0043227",
"GO:0097225",
"GO:0097729",
"GO:0110165",
"GO:0120025"
] | AF-Q96HJ3-F1-model_v6.pdb | 9606.ENSP00000330240 | [
"Q9UBK7"
] | [
"IPR025259",
"IPR045323"
] | {"IPR045323": [2, 352], "IPR025259": [142, 321]} | - Rab-like protein 2A | - IPR025259: Coiled-coil domain-containing protein 34/181 (domain) [142-321]
- IPR045323: Coiled-coil domain-containing protein 34 (family) [2-352] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0071840 (cellular component organiza... |
Q3UI66 | Coiled-coil domain-containing protein 34 | Involved in spermatogenesis. Has a probable role in anterograde intraflagellar transport which is essential for the formation of sperm flagella | Mus musculus (Mouse) | 367 | Cell projection, cilium, flagellum. Note=Mainly located in the mid-piece of sperm flagella | MRAAGPWRAASPAPCTRYLARCKPGFRPSSSFVVDLLVDSGDPGLEDVALTECLSPPSLSCSNSTLSLLSPLGHQSFPFGADDSEGEDEEALDEDARESESKVESLEGIEFQQRSSCEVESQDKQEKLVLLQHGSLTPWEMWFVGKEKEERGRLQQKFLEELNQQIEKRKEMEEREKRKIIAEVKHKEWVQKKNKQERKEREQKINKEMEEKEAKKREKEHLQEKAKEKYQEWLKKKKAEEYEKKKKEKEKEKQRQAELQEKKEIAEKKFKEWLENAKNKPRPAAKSYGYSSGKLTGFYSGNSYPEPTFYNPIPWKPIHM... | [
"GO:0003006",
"GO:0007276",
"GO:0007283",
"GO:0008150",
"GO:0019953",
"GO:0022414",
"GO:0032502",
"GO:0048232",
"GO:0048609",
"GO:0005575",
"GO:0005929",
"GO:0031514",
"GO:0036126",
"GO:0042995",
"GO:0043226",
"GO:0043227",
"GO:0097225",
"GO:0097729",
"GO:0110165",
"GO:0120025"... | [
"GO:0003006",
"GO:0007276",
"GO:0007283",
"GO:0008150",
"GO:0019953",
"GO:0022414",
"GO:0032502",
"GO:0048232",
"GO:0048609"
] | [] | [
"GO:0005575",
"GO:0005929",
"GO:0031514",
"GO:0036126",
"GO:0042995",
"GO:0043226",
"GO:0043227",
"GO:0097225",
"GO:0097729",
"GO:0110165",
"GO:0120025"
] | AF-Q3UI66-F1-model_v6.pdb | 10090.ENSMUSP00000028580 | null | [
"IPR025259",
"IPR045323"
] | {"IPR045323": [2, 357], "IPR025259": [136, 315]} | - IPR025259: Coiled-coil domain-containing protein 34/181 (domain) [136-315]
- IPR045323: Coiled-coil domain-containing protein 34 (family) [2-357] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0071840 (cellular component organization or biogenesis), GO:0044237 (cellular metabolic... | |
A0A8I3P7X4 | PAT complex subunit CCDC47 | Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes. The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occ... | Canis lupus familiaris (Dog) (Canis familiaris) | 483 | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Rough endoplasmic reticulum membrane; Single-pass type I membrane protein | MKASLAFCVVLLVFGSVSEAKFDDFEDEEDIVEYDDNDFAEFEDVTEDSVTESPQRVITTEDDEDETTVELEGQDENQEGDFEDADTQEGDTESEPYDDEEFEGYEDKPDTSSSKNKDPITIVDVPAHLQNSWESYYLEILMVTGLLAYIMNYIIGKNKNSRLAQAWFNTHRELLESNFTLVGDDGTNKEATSTGKLNQENEHIYNLWCSGRVCCEGMLIQLRFLKRQDLLNVLARMMRPVSDQVQIKVTMNDEDMDTYVFAVGTRKALVRLQKEMQDLSEFCSDKPKSGAKYGLPDSLAILSEMGEVTEGMMDTKMVHF... | [
"GO:0006996",
"GO:0007029",
"GO:0008104",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0033036",
"GO:0033365",
"GO:0045048",
"GO:0045184",
"GO:0051179",
"GO:0051205",
"GO:0051234",
"GO:0051641",
"GO:0051668",
"GO:0061024",
"GO:0071840",
"GO:0090150",
"GO:0160063"... | [
"GO:0006996",
"GO:0007029",
"GO:0008104",
"GO:0008150",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0033036",
"GO:0033365",
"GO:0045048",
"GO:0045184",
"GO:0051179",
"GO:0051205",
"GO:0051234",
"GO:0051641",
"GO:0051668",
"GO:0061024",
"GO:0071840",
"GO:0090150",
"GO:0160063"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0005829",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031984",
"GO:0032991",
"GO:0042175",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0072379",
"GO:0098827",
"GO:0110165",
"GO:0160064"... | AF-A0A8I3P7X4-F1-model_v6.pdb | null | null | [
"IPR012879"
] | {"IPR012879": [9, 481]} | - IPR012879: PAT complex subunit CCDC47 (family) [9-481] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0050896 (response to stimulus), GO:0042592 (homeostatic process), GO:0032502 (developmental process), GO:0009987 (cell... | |
Q5A761 | CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4 | Acts as a catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuc... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 787 | Cytoplasm. Nucleus | MNITNKFQHTPIQGQPQSNLQAQQILLSQLHQGQAQQQQQQQQQQQQQQQSSAGVLGSGFQPSDNFGESLNQNIYQNNYQRAQPSLQQQFFPQFQQSQQQPSQQANNASQLQQPYQPAQQMVRQTSHFQQQQQQQPSSQQFYSQQQASVLQQQQQQQIQLQSAHQQQSSLLNMNSINVDNPNSVYWQHQQQLCQISRGSNVPHYYARQYASNSRKAKNPYSEVKSVGLVEATRSMVASLEDEEEKKKKPINYQGTPTTSAALLHNKKSTQDIFEDDSMEEQRMRLKTQGKQLWCQLDLSGQGLVNISSKLFHYDFLESLY... | [
"GO:0006950",
"GO:0008150",
"GO:0009267",
"GO:0009272",
"GO:0009607",
"GO:0009987",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036170",
"GO:0036180",
"GO:0040007",
"GO:0042546",
"GO:0042592",
"GO:0042594",
"GO:0044085",
"GO:0044182",
"GO:0048878",
"GO:0050896"... | [
"GO:0006950",
"GO:0008150",
"GO:0009267",
"GO:0009272",
"GO:0009607",
"GO:0009987",
"GO:0030447",
"GO:0031667",
"GO:0031669",
"GO:0033554",
"GO:0036170",
"GO:0036180",
"GO:0040007",
"GO:0042546",
"GO:0042592",
"GO:0042594",
"GO:0044085",
"GO:0044182",
"GO:0048878",
"GO:0050896"... | [] | [] | AF-Q5A761-F1-model_v6.pdb | 237561.Q5A761 | [
"Q59WH0",
"A0A1D8PM93",
"A0A1D8PSH4",
"Q5APK0",
"A0A1D8PE87",
"A0A1D8PRG1",
"A0A1D8PQD2",
"A0A1D8PCW7",
"Q59Y36",
"A0A1D8PMA5",
"Q5A8L5",
"Q5ADI5",
"A0A1D8PDX9",
"Q5AAW3",
"A0A1D8PGR8",
"A0A1D8PUA6",
"A0A1D8PC71",
"Q59NY7",
"A0A1D8PM60"
] | [
"IPR036691",
"IPR005135",
"IPR001611",
"IPR050410",
"IPR003591",
"IPR032675"
] | {"IPR032675": [230, 417], "IPR036691": [418, 786], "IPR050410": [315, 778], "IPR005135": [459, 769], "IPR001611": [296, 382], "IPR003591": [316, 381]} | - General negative regulator of transcription subunit 1
- CCR4-NOT core DEDD family RNase subunit
- CCR4-NOT core subunit
- CCR4-NOT core ubiquitin-protein ligase subunit
- General negative regulator of transcription subunit
- General negative regulator of transcription subunit 3
- ATP-dependent RNA helicase DHH1
- CCR... | - IPR036691: Endonuclease/exonuclease/phosphatase superfamily (homologous_superfamily) [418-786]
- IPR005135: Endonuclease/exonuclease/phosphatase (domain) [459-769]
- IPR001611: Leucine-rich repeat (repeat) [296-382]
- IPR050410: CCR4/nocturin mRNA turnover and transcription (family) [315-778]
- IPR003591: Leucine-ric... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016787 (hydrolase activity), GO:0140098 (catalytic activity, acting on RNA), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0004518 (nuclease activity), G... |
P51882 | T-cell surface glycoprotein CD5 | Lymphoid-specific receptor expressed by all T-cells and in a subset of B-cells known as B1a cells. Plays a role in the regulation of TCR and BCR signaling, thymocyte selection, T-cell effector differentiation and immune tolerance. Acts by interacting with several ligands expressed on B-cells such as CD5L or CD72 and th... | Rattus norvegicus (Rat) | 491 | Cell membrane; Single-pass type I membrane protein | MDSHEVLLAATYLLGTLAAFCLGQSGRGFVGAQVMLSGSNSKCQGLVEVQMNGMKTVCSSSWRLSQDLWKNANEASTVCQQLGCGNPLALGHLTLWNRPKNQILCQGPPWSFSNCSTSSLGQCLPLSLVCLEPQKTTPLPTTTLPTTMPEPTAPPRLQLVPGHEGLRCTGVVEFYNGSRGGTILYKAKARPVDLGNLICKSLQCGSFLTHLSRIETAGTPAPAELRDPRPLPIRWEAQNGSCTSLQQCFQKTTVQEGSQALAVVCSDFQPKVQSRLVGGSSVCEGIAEVRQRSQWAALCDSSAARGPGRWEELCQEQQCG... | [
"GO:0005575",
"GO:0009986",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0009986",
"GO:0110165"
] | AF-P51882-F1-model_v6.pdb | 10116.ENSRNOP00000070123 | [
"A0A0G2K684",
"O35531",
"Q01621",
"F1LSA1",
"A0A0R4J8U1",
"P07725",
"D3ZWG3",
"Q64244",
"Q0P5T1",
"Q4QQW2",
"Q5BK59",
"G3V8U0",
"Q9QYE7",
"P13838",
"F1MAM7",
"P04157",
"F1LNH2",
"Q9Z2V2",
"Q63493",
"P20096",
"D4Q8I2",
"P26260",
"D4A5M2",
"D3ZD88",
"Q63204",
"P01581"... | [
"IPR036772",
"IPR003566",
"IPR001190"
] | {"IPR036772": [30, 369], "IPR003566": [1, 491], "IPR001190": [34, 364]} | - CD19 molecule
- T-cell surface glycoprotein CD4
- T-cell surface antigen CD2
- Cd72 molecule
- C-C motif chemokine receptor 7
- Antigen-presenting glycoprotein CD1d
- T-cell surface glycoprotein CD3 epsilon chain
- Leukosialin
- Proto-oncogene tyrosine-protein kinase LCK
- Integrin alpha-D | - IPR036772: SRCR-like domain superfamily (homologous_superfamily) [30-369]
- IPR003566: T-cell surface glycoprotein CD5 (family) [1-491]
- IPR001190: SRCR domain (domain) [34-364] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of ... |
Q59NH8 | Tyrosine-protein phosphatase CDC14 | Protein phosphatase which antagonizes mitotic cyclin- dependent kinase CDC28, the inactivation of which is essential for exit from mitosis. To access its substrates, is released from nucleolar sequestration during mitosis. Plays an essential in coordinating the nuclear division cycle with cytokinesis through the cytoki... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 542 | Nucleus, nucleolus. Cytoplasm. Bud neck. Cytoplasm, cytoskeleton, spindle pole. Cell septum. Note=Does not accumulate in the nucleolus in interphase cells. At the G1-S transition, starts to accumulate both in the nucleolus and the and the DAPI-staining region of the nucleus. At the S-G2 transition, starts to concentrat... | MHSSSVHVPLIEFLKNRIYLGAYDHHKRDTEDLAYFTVEDALPYNAFYMDFGPLNIGHLYRFAVLLHKKLNEDSTQGKGLVIYSSTSPKERANLACLLCCYMILLQNWAPHQVLQPIAQITPPLQAFRDAGYSSADYEITIQDVVYAMWRAKERGMIDLAKFDLDEYEQYERVDQGDFNVISKDFIAFASPQQSKRGGLNEPFQKVLEYFVENNVQLVVRLNSHLYDAKEFTKRNIKHIDMIFDDGTCPTLEYVQKFIGAAECIINKGGKIAVHCKAGLGRTGCLIGAHLIYTHGFTANECIAYMRMIRPGMVVGPQQHW... | [
"GO:0000278",
"GO:0000920",
"GO:0001403",
"GO:0006950",
"GO:0007049",
"GO:0007096",
"GO:0007346",
"GO:0008150",
"GO:0009267",
"GO:0009987",
"GO:0010564",
"GO:0030447",
"GO:0030448",
"GO:0031667",
"GO:0031669",
"GO:0032954",
"GO:0033554",
"GO:0036267",
"GO:0040007",
"GO:0042149"... | [
"GO:0000278",
"GO:0000920",
"GO:0001403",
"GO:0006950",
"GO:0007049",
"GO:0007096",
"GO:0007346",
"GO:0008150",
"GO:0009267",
"GO:0009987",
"GO:0010564",
"GO:0030447",
"GO:0030448",
"GO:0031667",
"GO:0031669",
"GO:0032954",
"GO:0033554",
"GO:0036267",
"GO:0040007",
"GO:0042149"... | [
"GO:0003674",
"GO:0003824",
"GO:0004721",
"GO:0008138",
"GO:0016787",
"GO:0016788",
"GO:0016791",
"GO:0042578",
"GO:0140096"
] | [
"GO:0000935",
"GO:0000936",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005730",
"GO:0005815",
"GO:0005816",
"GO:0005856",
"GO:0015630",
"GO:0030428",
"GO:0031974",
"GO:0031981",
"GO:0032153",
"GO:0043226",
"GO:0043227",
"GO:0043228",
"GO:0043229",
"GO:0043231",
"GO:0043232"... | AF-Q59NH8-F1-model_v6.pdb | 237561.Q59NH8 | [
"A0A1D8PDA6",
"A0A1D8PPK6",
"Q5AP97",
"A0A1D8PJ05",
"A0A1D8PEA9",
"Q5ABG0",
"A0A1D8PGP6",
"Q5ACY4",
"Q5A0A9",
"A0A1D8PCX9",
"Q5AP53",
"A0A1D8PCM0",
"A0A1D8PHR4",
"Q59V96",
"Q59KM8",
"Q5ALV8",
"A0A1D8PH53",
"A0A1D8PFB8",
"A0A1D8PK75",
"Q5ALY0",
"A0A1D8PKC6",
"Q59UQ6",
"Q5A... | [
"IPR044506",
"IPR003595",
"IPR016130",
"IPR000387",
"IPR029021",
"IPR050561",
"IPR000340",
"IPR020422",
"IPR029260"
] | {"IPR029021": [3, 336], "IPR050561": [36, 502], "IPR029260": [10, 152], "IPR044506": [161, 331], "IPR020422": [177, 334], "IPR000340": [201, 325], "IPR003595": [234, 328], "IPR000387": [255, 320], "IPR016130": [273, 283]} | - Cell cycle protein kinase DBF2
- Serine/threonine protein kinase
- Serine/threonine-protein kinase
- Ras family GTPase
- Oxidant-induced cell-cycle arrest protein 5
- separase
- Mob1p
- Mitosis inhibitor protein kinase SWE1
- Cdh1p
- Serine/threonine-protein kinase CBK1 | - IPR044506: Dual-specificity phosphatase CDC14, C-terminal (domain) [161-331]
- IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [234-328]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [273-283]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [255-320]
- IPR029021:... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0004721 (phosphoprotein phosphatase activity), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0042578 (phosphoric ester hydrola... |
Q5ANA3 | Pleiotropic ABC efflux transporter of multiple drugs CDR1 | Pleiotropic ABC efflux transporter that confers resistance to numerous chemicals including anisomycin, cycloheximide, fluconazole, miconazole, ketoconazole, itriconazole, nystatin, terbinafine, amorolfine, brefeldin A, amphotericin B, fluphenazine, as well as estrogen. Plays a role in farnesol-induced apoptotic process... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,501 | Cell membrane; Multi-pass membrane protein. Note=Accumulates at membrane rafts. Both ergosterol and sphingolipids are essential for targeting to membrane rafts. Mislocalizes to the vacuole in absence of FZO1 | MSDSKMSSQDESKLEKAISQDSSSENHSINEYHGFDAHTSENIQNLARTFTHDSFKDDSSAGLLKYLTHMSEVPGVNPYEHEEINNDQLNPDSENFNAKFWVKNLRKLFESDPEYYKPSKLGIGYRNLRAYGVANDSDYQPTVTNALWKLATEGFRHFQKDDDSRYFDILKSMDAIMRPGELTVVLGRPGAGCSTLLKTIAVNTYGFHIGKESQITYDGLSPHDIERHYRGDVIYSAETDVHFPHLSVGDTLEFAARLRTPQNRGEGIDRETYAKHMASVYMATYGLSHTRNTNVGNDFVRGVSGGERKRVSIAEASLSG... | [
"GO:0006810",
"GO:0006869",
"GO:0008150",
"GO:0009636",
"GO:0009987",
"GO:0010876",
"GO:0015748",
"GO:0015850",
"GO:0015903",
"GO:0015914",
"GO:0016043",
"GO:0033036",
"GO:0034204",
"GO:0042221",
"GO:0042908",
"GO:0045117",
"GO:0045332",
"GO:0046618",
"GO:0050896",
"GO:0051179"... | [
"GO:0006810",
"GO:0006869",
"GO:0008150",
"GO:0009636",
"GO:0009987",
"GO:0010876",
"GO:0015748",
"GO:0015850",
"GO:0015903",
"GO:0015914",
"GO:0016043",
"GO:0033036",
"GO:0034204",
"GO:0042221",
"GO:0042908",
"GO:0045117",
"GO:0045332",
"GO:0046618",
"GO:0050896",
"GO:0051179"... | [
"GO:0000166",
"GO:0003674",
"GO:0003824",
"GO:0005215",
"GO:0005319",
"GO:0005488",
"GO:0005496",
"GO:0005524",
"GO:0005548",
"GO:0008289",
"GO:0008525",
"GO:0015244",
"GO:0015247",
"GO:0015665",
"GO:0016462",
"GO:0016787",
"GO:0016817",
"GO:0016818",
"GO:0016887",
"GO:0017076"... | [
"GO:0005575",
"GO:0005576",
"GO:0005886",
"GO:0009986",
"GO:0016020",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043230",
"GO:0065010",
"GO:0071944",
"GO:0110165",
"GO:1903561"
] | AF-Q5ANA3-F1-model_v6.pdb | 237561.Q5ANA3 | [
"Q5ABU7",
"Q59QC7",
"Q92208",
"Q9HF77",
"A0A1D8PHN5",
"A0A1D8PIM2",
"Q5AJG1",
"Q59VG6",
"A0A1D8PN96",
"Q5A6P6"
] | [
"IPR034001",
"IPR010929",
"IPR029481",
"IPR027417",
"IPR003593",
"IPR013525",
"IPR034003",
"IPR017871",
"IPR003439",
"IPR005285"
] | {"IPR027417": [154, 1100], "IPR005285": [94, 1492], "IPR029481": [45, 146], "IPR003439": [150, 1103], "IPR034001": [167, 386], "IPR003593": [179, 1079], "IPR013525": [496, 1392], "IPR010929": [716, 807], "IPR034003": [858, 1085], "IPR017871": [303, 317]} | - Multidrug resistance protein 1
- Lanosterol 14-alpha demethylase
- Major facilitator superfamily multidrug transporter FLU1
- Transcription factor TAC1
- Sterol uptake control protein 2
- Delta(7)-sterol 5(6)-desaturase ERG3
- ATP-binding cassette transporter
- Sphingoid long-chain base transporter RSB1
- MFS antipor... | - IPR034001: ATP-binding cassette transporter, PDR-like subfamily G, domain 1 (domain) [167-386]
- IPR010929: CDR ABC transporter (domain) [716-807]
- IPR029481: Pleiotropic ABC efflux transporter, N-terminal domain (domain) [45-146]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfami... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005215 (transporter activity), GO:0140657 (ATP-dependent activity), GO:0140326 (ATPase-coupled intramembrane lipid transporter activity), GO:0005319 (lipid transporter activity), GO:0140303 (intramembrane lipid transporter activity), GO:0005548 (phospholipid... |
Q07730 | Extent of cell elongation protein 1 | Secreted protein cleaved by KEX2 in 8 similar peptides (ECE1- I to ECE1-VIII). Stimulates biofilm formation | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 271 | Secreted | MKFSKIACATVFALSSQAAIIHHAPEFNMKRDVAPAAPAAPADQAPTVPAPQEFNTAITKRSIIGIIMGILGNIPQVIQIIMSIVKAFKGNKREDIDSVVAGIIADMPFVVRAVDTAMTSVASTKRDGANDDVANAVVRLPEIVARVATGVQQSIENAKRDGVPDVGLNLVANAPRLISNVFDGVSETVQQAKRDGLEDFLDELLQRLPQLITRSAESALKDSQPVKRDAGSVALSNLIKKSIETVGIENAAQIVSERDISSLIEEYFGKA | [
"GO:0003674",
"GO:0005488",
"GO:0005539",
"GO:0097367",
"GO:0140912"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005539",
"GO:0097367",
"GO:0140912"
] | [] | AF-Q07730-F1-model_v6.pdb | 237561.Q07730 | [
"Q874L3",
"Q59TP1",
"Q5A8T4",
"Q5A8I8",
"Q5ABW5",
"Q59ME1",
"Q5ABE2",
"Q5ALC8",
"Q59TL7",
"Q59XB5"
] | null | NaN | - Agglutinin-like protein 3
- Hyphal wall protein 1
- Cell wall protein RBT1
- Hyphally regulated cell wall protein 1
- Hypha-specific G1 cyclin-related protein 1
- Transcriptional regulatory protein UME6
- Enhanced filamentous growth protein 1
- Agglutinin-like protein 1
- Secreted aspartic protease 5
- Induced during... | Molecular Function (MF): GO:0003674 (molecular function), GO:0098772 (molecular function regulator activity), GO:0005488 (binding), GO:0030545 (signaling receptor regulator activity), GO:0140677 (molecular function activator activity), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0030546 (s... | |
P0AE60 | Cell division activator CedA | Activates the cell division inhibited by chromosomal DNA over-replication | Escherichia coli (strain K12) | 80 | null | MKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVWMLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQEGEVTE | [
"GO:0008150",
"GO:0050789",
"GO:0050794",
"GO:0051302",
"GO:0065007"
] | [
"GO:0008150",
"GO:0050789",
"GO:0050794",
"GO:0051302",
"GO:0065007"
] | [] | [] | AF-P0AE60-F1-model_v6.pdb | 511145.b1731 | [
"Q2MB44"
] | [
"IPR019666",
"IPR038463"
] | {"IPR038463": [14, 80], "IPR019666": [1, 80]} | - Uncharacterized protein YdjO | - IPR019666: Cell division activator CedA (family) [1-80]
- IPR038463: CedA-like superfamily (homologous_superfamily) [14-80] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0003690 (double-stranded DNA binding)
Biological Process (BP): GO:0008150 (biological ... |
A6NL82 | Cilia- and flagella-associated protein 144 | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating | Homo sapiens (Human) | 134 | Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme | MAGHPKEKVIPDEVHQNQILRELYLKELRTQKLYTQYHVNPLRKIHTVTRKPMSWHDNLEEPADARFLNLIHHAAQGPRKKYPETQTENQEVGWDLEPLINPERHDRRLNHFRVCSDITLYKAKTWGLGDDHHK | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0008017",
"GO:0008092",
"GO:0015631",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005856",
"GO:0005874",
"GO:0005879",
"GO:0005881",
"GO:0005929",
"GO:0005930",
"GO:0015630",
"GO:0032838",
"GO:0042995",
"GO:0043226",
"GO:0043227"... | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0008017",
"GO:0008092",
"GO:0015631"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005856",
"GO:0005874",
"GO:0005879",
"GO:0005881",
"GO:0005929",
"GO:0005930",
"GO:0015630",
"GO:0032838",
"GO:0042995",
"GO:0043226",
"GO:0043227",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0097014",
"GO:0099080",
"GO:0099081"... | AF-A6NL82-F1-model_v6.pdb | 9606.ENSP00000334415 | [
"A6NJV1",
"Q9Y5B8",
"Q5VTT2",
"Q5T5A4",
"Q5VU69",
"Q969V4",
"Q8TCI3",
"Q6F5E7",
"Q8WU44",
"Q9NVW6",
"Q9H653",
"Q9UL16",
"A4QMS7",
"Q9Y6A4",
"P68371",
"Q8N906",
"B7ZBJ0",
"Q6PJF6",
"Q6ZQR2",
"Q9H1V9",
"Q8WW24",
"Q8TC29",
"Q96LQ6",
"Q71U36",
"Q9UIF3",
"Q9NUP4",
"Q99... | [
"IPR029214"
] | {"IPR029214": [5, 129]} | - Tektin-4
- RIB43A-like with coiled-coils protein 2
- Tektin-1
- Tektin-2
- Sperm acrosome-associated protein 9
- Cilia- and flagella-associated protein 45
- Protein Flattop
- Cilia- and flagella-associated protein 52
- Tektin-3
- Ciliary microtubule inner protein 2C | - IPR029214: Cilia- and flagella-associated protein 144 (family) [5-129] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0022414 (reproductive process), GO:00325... |
Q9C0B2 | Cilia- and flagella-associated protein 74 | As part of the central apparatus of the cilium axoneme may play a role in cilium movement. May play an important role in sperm architecture and function | Homo sapiens (Human) | 1,584 | Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme | MEDDGSLLPEDELLADALLLEDERDELEDPEFDIKCLLQEAEDDVDPGHSSSVKELDTDADKLKKKTAEDRTQAFHLRQNLSALDKMHEEQELFTEKMRGELRACRQRRDLIDKQQEAVAAEIATEEEAGNMAAVGRLQAVSRRLFAELENERDLQSRTEAVLKESENTMWHIEIQEGRLEAFRTADREEVEATGRRLQVRAAEQLCREQEALGKVERNRLLRIRKSLNTQKELGLRHQKLLEDARKNHKVAVRFLKASLGRIREQEKKEEMECHEYMRRRMDAVVALKGSISANRDTLRKFQAWDRAKAELAEQRVQAE... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0005929",
"GO:0031514",
"GO:0036126",
"GO:0042995",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0097729",
"GO:0110165",
"GO:0120025"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0005929",
"GO:0031514",
"GO:0036126",
"GO:0042995",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0097729",
"GO:0110165",
"GO:0120025"
] | AF-Q9C0B2-F1-model_v6.pdb | 9606.ENSP00000417061 | [
"Q4G0U5",
"Q96M69",
"Q8N4N9"
] | [
"IPR013783",
"IPR056306",
"IPR056307",
"IPR056310"
] | {"IPR013783": [611, 1477], "IPR056306": [618, 800], "IPR056307": [802, 914], "IPR056310": [920, 1014]} | - Leucine-rich repeat and guanylate kinase domain-containing protein
- Gamma-aminobutyric acid receptor subunit delta
- Cilia- and flagella-associated protein 221 | - IPR013783: Immunoglobulin-like fold (homologous_superfamily) [611-1477]
- IPR056306: CFAP74, second Ig-like domain (domain) [618-800]
- IPR056307: CFAP74, third Ig-like domain (domain) [802-914]
- IPR056310: CFAP74, fourth Ig-like domain (domain) [920-1014] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0048869 (cellular developmental proc... |
Q59YH3 | G1/S-specific cyclin CCN1 | G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition and for maintenance of filamentous growth. Through binding to CDC28 controls the phosphorylation of CDC11 and SEC2 upon induction of filamentous growth | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 693 | null | MTSLQQQRVKYGPPHHIKRRPYHPILESLEFQTNQHLIQEYSLDIVNTLSQLESLTLVNPAMIDLQPEIQWFMRPFLLDFLIELHSSFKLQPTTLFLCLNIIDRYCAKRIVFKRHYQLVGCTALWIASKYEDKKSRVPTLKELTIMCRNAYDEEMFVQMEMHILSTLDWSIGHPTLEDCLQLAIDSNNLSNNTTNDIENKSVRPNRKSSISSAVTAVARFLCELSLYDKYFLSVPPSLIAITANLLSCSMLQIPHASITLKNLIEQEIINPQQKKQKKALSSNSSRTTTASYTHQNQSDVRHSSFDEDIDLDSGDEEDDD... | [
"GO:0000082",
"GO:0000278",
"GO:0002831",
"GO:0002833",
"GO:0007049",
"GO:0007163",
"GO:0008150",
"GO:0009268",
"GO:0009607",
"GO:0009628",
"GO:0009987",
"GO:0010570",
"GO:0022402",
"GO:0030011",
"GO:0030447",
"GO:0030448",
"GO:0036176",
"GO:0036177",
"GO:0036178",
"GO:0036180"... | [
"GO:0000082",
"GO:0000278",
"GO:0002831",
"GO:0002833",
"GO:0007049",
"GO:0007163",
"GO:0008150",
"GO:0009268",
"GO:0009607",
"GO:0009628",
"GO:0009987",
"GO:0010570",
"GO:0022402",
"GO:0030011",
"GO:0030447",
"GO:0030448",
"GO:0036176",
"GO:0036177",
"GO:0036178",
"GO:0036180"... | [
"GO:0003674",
"GO:0003824",
"GO:0004672",
"GO:0016301",
"GO:0016538",
"GO:0016740",
"GO:0016772",
"GO:0016773",
"GO:0019207",
"GO:0019887",
"GO:0019914",
"GO:0030234",
"GO:0098772",
"GO:0140096"
] | [] | AF-Q59YH3-F1-model_v6.pdb | 237561.Q59YH3 | [
"Q59V96",
"A0A1D8PH53",
"A0A1D8PK75",
"A0A1D8PGV7",
"Q5AP97",
"A0A1D8PPK6",
"A0A1D8PDA6",
"Q5ACY4",
"Q5ABG0",
"G1UB61"
] | [
"IPR013763",
"IPR014399",
"IPR036915",
"IPR004367",
"IPR039361",
"IPR006671",
"IPR048258"
] | {"IPR036915": [32, 261], "IPR014399": [4, 611], "IPR039361": [38, 270], "IPR006671": [44, 171], "IPR013763": [79, 165], "IPR004367": [174, 309], "IPR048258": [74, 105]} | - Nucleoporin NSP1
- Cyclin-dependent kinase 1
- Negative regulator of the PHO system
- Mitosis inhibitor protein kinase SWE1
- Serine/threonine-protein kinase
- Ubiquitin-protein transferase activating protein
- Cdh1p
- CDC20/Fizzy WD40 domain-containing protein
- Cyclin-dependent protein kinase-activating kinase
- Se... | - IPR013763: Cyclin-like domain (domain) [79-165]
- IPR014399: Cyclin CLN (family) [4-611]
- IPR036915: Cyclin-like superfamily (homologous_superfamily) [32-261]
- IPR004367: Cyclin, C-terminal domain (domain) [174-309]
- IPR039361: Cyclin (family) [38-270]
- IPR006671: Cyclin, N-terminal (domain) [44-171]
- IPR048258:... | Molecular Function (MF): GO:0003674 (molecular function), GO:0016538 (cyclin-dependent protein serine/threonine kinase regulator activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biolo... |
P17411 | 6-phospho-beta-glucosidase | Hydrolyzes a wide variety of P-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, gentiobiose-6P, methyl-beta- glucoside-6P and p-nitrophenyl-beta-D-glucopyranoside-6P. Is also able to hydrolyze phospho-N,N'-diacetylchitobiose | Escherichia coli (strain K12) | 450 | null | MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVSELWLVDVEGGKPKLDIIFDLCQRMIDNAGVPMKLYKTLDRREALKDADFVTTQLRVGQLPARELDERIPLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVEELCPNAWVINFTNPAGMVTEAVYRHTGFKRFIGVCNIPIGMKMFIRDVLMLKDSDDLSIDLFGLNHMVFIKDVLINGKSRFAELLDGVASGQLKASSVKNIFDLPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEYYKGGARAQVVQKVEKQLFELYKNPELKVKPKELEQRGGAYYSDA... | [
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0052777",
"GO:0052778",
"GO:1901135",
"GO:1901136"
] | [
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0052777",
"GO:0052778",
"GO:1901135",
"GO:1901136"
] | [] | [] | AF-P17411-F1-model_v6.pdb | 511145.b1734 | [
"Q59375",
"Q57128",
"Q6BF64",
"Q47703",
"Q2MAU7",
"P17410",
"P78276",
"P77435",
"P36938",
"P77332",
"Q2M667",
"P69795",
"Q46829",
"Q2M839",
"Q2M6S9",
"P76913",
"Q2MC23"
] | [
"IPR036291",
"IPR001088",
"IPR015955",
"IPR019802",
"IPR022616"
] | {"IPR036291": [4, 167], "IPR015955": [171, 448], "IPR001088": [3, 440], "IPR022616": [199, 415], "IPR019802": [141, 172]} | - PTS system N,N'-diacetylchitobiose-specific EIIA component
- PTS system N,N'-diacetylchitobiose-specific EIIA component
- PTS system N,N'-diacetylchitobiose-specific EIIA component
- PTS system N,N'-diacetylchitobiose-specific EIIA component
- PTS system N,N'-diacetylchitobiose-specific EIIC component
- PTS system N,... | - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [4-167]
- IPR001088: Glycoside hydrolase, family 4 (family) [3-440]
- IPR015955: Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (homologous_superfamily) [171-448]
- IPR019802: Glycoside hydrolase, family 4, conserved site (conserve... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0016798 (hydrolase activity, acting on glycosyl bonds), GO:0004553 (hydrolase activity, hydrolyzing O... |
Q5AHA0 | Histidine protein kinase 1 | Histidine kinase involved in a two-component signaling pathway that regulates cell wall mannan and glucan biosynthesis. Regulates quorum sensing as well as hyphal formation, biofilm formation, chlamidospore formation, and virulence. Plays a prominent role in phagocyte activation. Involved in the covering of the most po... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 2,471 | null | MSMNFFNSSEPARDHKPDQEKETVMTTEHYEFERPDVKAIRNFKFFRSDETETKKGPNLHISDLSPLESQSVPPSALSLNHSIIPDQYERRQDTPDPIHTPEISLSDYLYDQTLSPQGFDNSRENFNIHKTIASLFEDNSSVVSQESTDDTKTTLSSETCDSFSLNNASYLTNINFVQNHLQYLSQNVLGNRTSNSLPPSSSSQIDFDASNLTPDSIPGYILNKKLGSVHQSTDSVYNAIKIPQNEEYNCCTKASASQNPTNLNSKVIVRLSPNIFQNLSLSRFLNEWYILSGKHSSKEHQIWSNESLTNEYVQDKTIPT... | [
"GO:0000302",
"GO:0001402",
"GO:0002831",
"GO:0002833",
"GO:0006950",
"GO:0006979",
"GO:0007154",
"GO:0007162",
"GO:0007165",
"GO:0008150",
"GO:0009272",
"GO:0009607",
"GO:0009987",
"GO:0010570",
"GO:0022407",
"GO:0022408",
"GO:0023052",
"GO:0030100",
"GO:0030155",
"GO:0030447"... | [
"GO:0000302",
"GO:0001402",
"GO:0002831",
"GO:0002833",
"GO:0006950",
"GO:0006979",
"GO:0007154",
"GO:0007162",
"GO:0007165",
"GO:0008150",
"GO:0009272",
"GO:0009607",
"GO:0009987",
"GO:0010570",
"GO:0022407",
"GO:0022408",
"GO:0023052",
"GO:0030100",
"GO:0030155",
"GO:0030447"... | [] | [] | AF-Q5AHA0-F1-model_v6.pdb | 237561.Q5AHA0 | null | [
"IPR004358",
"IPR001789",
"IPR027417",
"IPR036890",
"IPR011009",
"IPR041664",
"IPR003018",
"IPR003594",
"IPR005467",
"IPR029016",
"IPR000719",
"IPR011006",
"IPR003661",
"IPR036097"
] | {"IPR011009": [462, 637], "IPR027417": [687, 903], "IPR029016": [1821, 1988], "IPR036097": [1983, 2063], "IPR036890": [2052, 2228], "IPR011006": [2338, 2465], "IPR000719": [358, 636], "IPR041664": [690, 880], "IPR003018": [1830, 1975], "IPR003661": [1997, 2062], "IPR005467": [2004, 2225], "IPR003594": [2109, 2225], "IP... | - IPR004358: Signal transduction histidine kinase-related protein, C-terminal (domain) [2150-2222]
- IPR001789: Signal transduction response regulator, receiver domain (domain) [2339-2466]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [687-903]
- IPR036890: Histidine kinase/H... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016779 (nucleotidyltransferase activity), GO:0070566 (adenylyltransferase activity)
Biological Process (BP): GO:... | |
O70303 | Lipid transferase CIDEB | Lipid transferase specifically expressed in hepatocytes, which promotes unilocular lipid droplet formation by mediating lipid droplet fusion. Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage. Localizes on the lipid droplet surface, at focal contact sites between lipid dr... | Mus musculus (Mouse) | 219 | Lipid droplet. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Cytoplasmic vesicle, COPI-coated vesicle. Note=Enriched at lipid droplet contact sites | MEYLSAFNPNGLLRSVSTVSSELSRRVWNSAPPPQRPFRVCDHKRTVRKGLTAASLQELLDKVLETLLLRGVLTLVLEEDGTAVDSEDFFQLLEDDTCLMVLEQGQSWSPKSGMLSYGLGREKPKHSKDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKRVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGADRWQWHGQRHLHS | [
"GO:0003674",
"GO:0005215",
"GO:0005319",
"GO:0005488",
"GO:0005543",
"GO:0008289",
"GO:0036094",
"GO:0043167",
"GO:0043168",
"GO:0060090",
"GO:0070300",
"GO:0120013",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0005794",
"GO:0005811",
"GO:0012505"... | [] | [
"GO:0003674",
"GO:0005215",
"GO:0005319",
"GO:0005488",
"GO:0005543",
"GO:0008289",
"GO:0036094",
"GO:0043167",
"GO:0043168",
"GO:0060090",
"GO:0070300",
"GO:0120013"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0005794",
"GO:0005811",
"GO:0012505",
"GO:0012506",
"GO:0012507",
"GO:0016020",
"GO:0030117",
"GO:0030120",
"GO:0030127",
"GO:0030133",
"GO:0030134",
"GO:0030135",
"GO:0030658",
"GO:0030659",
"GO:0030662"... | AF-O70303-F1-model_v6.pdb | 10090.ENSMUSP00000001497 | [
"Q8CGG8"
] | [
"IPR003508"
] | {"IPR003508": [34, 110]} | - Apolipoprotein B-100 | - IPR003508: CIDE-N domain (domain) [34-110] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular ... |
P56198 | Lipid transferase CIDEC | Lipid transferase specifically expressed in white adipose tissue, which promotes unilocular lipid droplet formation by mediating lipid droplet fusion. Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage. Localizes on the lipid droplet surface, at focal contact sites between... | Mus musculus (Mouse) | 239 | Lipid droplet. Endoplasmic reticulum. Nucleus. Note=Diffuses quickly on lipid droplet surface, but becomes trapped and clustered at lipid droplet contact sites, thereby enabling its rapid enrichment at lipid droplet contact sites | MDYAMKSLSLLYPRSLSRHVAVSTAVVTQQLVSKPSRETPRARPCRVSTADRKVRKGIMAHSLEDLLNKVQDILKLKDKPFSLVLEEDGTIVETEEYFQALAKDTMFMVLLKGQKWKPPSEQRKKRAQLALSQKPTKKIDVARVTFDLYKLNPQDFIGCLNVKATLYDTYSLSYDLHCYKAKRIVKEMLRWTLFSMQATGHMLLGTSSYMQQFLDATEEEQPAKAKPSSLLPACLKMLQ | [
"GO:0006996",
"GO:0008150",
"GO:0009892",
"GO:0009894",
"GO:0009895",
"GO:0009987",
"GO:0016043",
"GO:0019216",
"GO:0019222",
"GO:0019915",
"GO:0034389",
"GO:0045833",
"GO:0048284",
"GO:0048519",
"GO:0048523",
"GO:0050789",
"GO:0050794",
"GO:0050994",
"GO:0050995",
"GO:0065007"... | [
"GO:0006996",
"GO:0008150",
"GO:0009892",
"GO:0009894",
"GO:0009895",
"GO:0009987",
"GO:0016043",
"GO:0019216",
"GO:0019222",
"GO:0019915",
"GO:0034389",
"GO:0045833",
"GO:0048284",
"GO:0048519",
"GO:0048523",
"GO:0050789",
"GO:0050794",
"GO:0050994",
"GO:0050995",
"GO:0065007"... | [
"GO:0001786",
"GO:0003674",
"GO:0005215",
"GO:0005319",
"GO:0005488",
"GO:0005543",
"GO:0008289",
"GO:0030674",
"GO:0035091",
"GO:0036094",
"GO:0043167",
"GO:0043168",
"GO:0060090",
"GO:0070300",
"GO:0072341",
"GO:0120013",
"GO:0140693"
] | [] | AF-P56198-F1-model_v6.pdb | 10090.ENSMUSP00000108712 | [
"Q9DC68",
"Q8K3Q8",
"Q8BVZ1",
"Q4V9X2",
"Q61280",
"Q8R400",
"Q8BNV5",
"P37238",
"P04117",
"Q8CDI9",
"Q9DCF6",
"Q9DCL0",
"Q9CWJ7",
"Q91XE9",
"Q08857",
"Q9DBG5",
"Q8CGN5"
] | [
"IPR003508"
] | {"IPR003508": [41, 118]} | - Lipid transferase CIDEA
- Perilipin-1
- Perilipin-4
- Hormone-sensitive lipase
- Adiponectin
- Platelet glycoprotein 4
- Peroxisome proliferator-activated receptor gamma
- Fatty acid-binding protein, adipocyte
- Complement factor D
- Scavenger receptor class B member 1 | - IPR003508: CIDE-N domain (domain) [41-118] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0046983 (protein dimerization activity), GO:0042803 (protein homodimerization activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular ... |
O43734 | E3 ubiquitin ligase TRAF3IP2 | E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target protein, enhancing protein-protein interaction and cell signaling. Transfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein. Essential adapter molecule in IL17A-mediated signaling. Upon IL17A stimulation, i... | Homo sapiens (Human) | 574 | null | MPPQLQETRMNRSIPVEVDESEPYPSQLLKPIPEYSPEEESEPPAPNIRNMAPNSLSAPTMLHNSSGDFSQAHSTLKLANHQRPVSRQVTCLRTQVLEDSEDSFCRRHPGLGKAFPSGCSAVSEPASESVVGALPAEHQFSFMEKRNQWLVSQLSAASPDTGHDSDKSDQSLPNASADSLGGSQEMVQRPQPHRNRAGLDLPTIDTGYDSQPQDVLGIRQLERPLPLTSVCYPQDLPRPLRSREFPQFEPQRYPACAQMLPPNLSPHAPWNYHYHCPGSPDHQVPYGHDYPRAAYQQVIQPALPGQPLPGASVRGLHPVQ... | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005886",
"GO:0009898",
"GO:0016020",
"GO:0019897",
"GO:0019898",
"GO:0031234",
"GO:0071944",
"GO:0098552",
"GO:0098562",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005886",
"GO:0009898",
"GO:0016020",
"GO:0019897",
"GO:0019898",
"GO:0031234",
"GO:0071944",
"GO:0098552",
"GO:0098562",
"GO:0110165"
] | AF-O43734-F1-model_v6.pdb | 9606.ENSP00000345984 | [
"Q9Y6K9",
"Q9NSR6",
"Q96F46",
"Q9BYU0",
"Q9NRM6",
"Q9BR97",
"Q9UNL1",
"Q96NT2",
"Q9Y4K3",
"O75327",
"Q92467",
"Q5T2P0",
"Q6FHY1",
"Q9BVQ5"
] | [
"IPR013568",
"IPR053047"
] | {"IPR053047": [1, 574], "IPR013568": [409, 552]} | - TNF receptor-associated factor 3
- Interleukin-17 receptor A
- TNF receptor-associated factor 6
- NF-kappa-B essential modulator
- Inhibitor of nuclear factor kappa-B kinase subunit beta
- Interleukin-17 receptor C
- Interleukin-17A
- TNF receptor-associated factor 5
- Interleukin-17 receptor B
- Heat shock protein H... | - IPR013568: SEFIR domain (domain) [409-552]
- IPR053047: E3 ubiquitin ligase TRAF3IP2 (family) [1-574] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0019787 (ubiquitin-like protein transferase ... |
Q1L8T5 | Cingulin | Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Note=Localizes to the apical junction complex composed of tight and adherens junctions | Danio rerio (Zebrafish) (Brachydanio rerio) | 1,161 | Cell junction, tight junction | MSSLSADRKPPLDYGVQIRFIKDLDDAGGGFPDKSRLANGVGGVSNGTSSPSKYGVAVRVQGISGQPYVVLQDGEKGDSYGVQLKTQPQIQSAPPVVSQTSPYNTLLLGQREGARTPQGSYNPTDQPSSPDEDFGSPLRRPPGDGQAGTQGEAEPRTTERFTPSALAPKLDKKDNDAFNEAGLRKVKQNGIGSSLNGTGLNGSFPPPSSAQDEDQAPAIDTKSLAPINKLISRFGGGGGGSGDILNSEAQTRPRLDNRVRSQSADALNKPSEEASSTSPTINPYAPNTSATVPKLNSTKPSSTGSLGRDATSVAKVAAIP... | [
"GO:0007275",
"GO:0008150",
"GO:0009888",
"GO:0032501",
"GO:0032502",
"GO:0048731",
"GO:0048856",
"GO:0048880",
"GO:0048881",
"GO:0048882",
"GO:0048915",
"GO:0048916",
"GO:0048925"
] | [
"GO:0007275",
"GO:0008150",
"GO:0009888",
"GO:0032501",
"GO:0032502",
"GO:0048731",
"GO:0048856",
"GO:0048880",
"GO:0048881",
"GO:0048882",
"GO:0048915",
"GO:0048916",
"GO:0048925"
] | [] | [] | AF-Q1L8T5-F1-model_v6.pdb | 7955.ENSDARP00000102223 | [
"A0A0G2KI74",
"A0A2R8QMK9",
"E7F4U1",
"A0A0R4I9Z3",
"A2RUX1",
"A0A0R4ILP3",
"F1REH9",
"A0A286YAR8"
] | [
"IPR002928"
] | {"IPR002928": [778, 1118]} | - Rho guanine nucleotide exchange factor 2 isoform X1
- Rho guanine nucleotide exchange factor 2
- Rho guanine nucleotide exchange factor 18a isoform X1 | - IPR002928: Myosin tail (domain) [778-1118] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0003779 (actin binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (mul... |
Q96SZ6 | Mitochondrial tRNA methylthiotransferase CDK5RAP1 | Methylthiotransferase that catalyzes the conversion of N6- (dimethylallyl)adenosine (i(6)A) to 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 (adjacent to the 3'-end of the anticodon) of four mitochondrial DNA-encoded tRNAs (Ser(UCN), Phe, Tyr and Trp). Essential for efficient and highly accurate... | Homo sapiens (Human) | 601 | Mitochondrion | MHPLQCVLQVQRSLGWGPLASVSWLSLRMCRAHSSLSSTMCPSPERQEDGARKDFSSRLAAGPTFQHFLKSASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAWSILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGILGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMPVQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQVFLPPRPPKVLGLQGLKEVTLLGQNVNS... | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016782",
"GO:0035596",
"GO:0035597",
"GO:0050497",
"GO:0140098",
"GO:0140101",
"GO:0140640",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0005737",
"GO:0005739",
"GO:0005759",
"GO:0005829",
"GO:0031974",
"GO:0031981"... | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016782",
"GO:0035596",
"GO:0035597",
"GO:0050497",
"GO:0140098",
"GO:0140101",
"GO:0140640"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0005737",
"GO:0005739",
"GO:0005759",
"GO:0005829",
"GO:0031974",
"GO:0031981",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0043233",
"GO:0070013",
"GO:0110165"
] | AF-Q96SZ6-F1-model_v6.pdb | 9606.ENSP00000217372 | [
"Q00535",
"Q9NXT7",
"Q9Y3A8",
"Q9NT95",
"Q5U0G3",
"Q9NQT4"
] | [
"IPR006463",
"IPR038135",
"IPR005839",
"IPR058240",
"IPR020612",
"IPR002792",
"IPR006638",
"IPR013848",
"IPR007197",
"IPR023404"
] | {"IPR038135": [100, 234], "IPR058240": [245, 508], "IPR023404": [246, 518], "IPR005839": [98, 594], "IPR006463": [98, 591], "IPR007197": [98, 594], "IPR013848": [100, 220], "IPR006638": [248, 501], "IPR002792": [515, 590], "IPR020612": [252, 272]} | - Exosome complex component RRP40
- Exosome complex component RRP46
- Cyclin-dependent kinase 5
- tRNA dimethylallyltransferase
- Cyclin-dependent kinase 5 activator 1
- Pre-mRNA-processing factor 40 homolog B | - IPR006463: tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB (family) [98-591]
- IPR038135: Methylthiotransferase, N-terminal domain superfamily (homologous_superfamily) [100-234]
- IPR005839: Methylthiotransferase (family) [98-594]
- IPR058240: Radical SAM superfamily (homologous_superfamily) [245-508]
- I... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0051540 (metal cluster binding), GO:0016782 (transferase activity, transferring sulphur-containing groups), GO:0051536 (iron-sulfur cluster binding), GO:0051539 (4 iron,... |
Q8GX93 | Chloride channel protein CLC-e | Voltage-gated thylakoid chloride (Cl) channel/transporter involved in chloride homeostasis after transition from light to dark. Influences chloroplast ultrastructure and subsequent photosynthetic electron transport. During photosynthetic response on transition from dark to low light, involved in a sequential mechanism ... | Arabidopsis thaliana (Mouse-ear cress) | 710 | Membrane; Multi-pass membrane protein | MAATLPLCAALRSPVSSRRFAPIHKTDVPFQFNVVLSPFFGSVAIGGRIFPRLPAAKQETDQDEVGFDQQPSQELAIASACLVGVLTGVSVVLFNNCVHLLRDFSWDGIPDRGASWLREAPIGSNWLRVILVPTIGGLVVSILNQLRESAGKSTGDSHSSLDRVKAVLRPFLKTVAACVTLGTGNSLGPEGPSVEIGASIAKGVNSLFNKSPQTGFSLLAAGSAAGISSGFNAAVAGCFFAVESVLWPSSSTDSSTSLPNTTSMVILSAVTASVVSEIGLGSEPAFKVPDYDFRSPGELPLYLLLGALCGLVSLALSRCT... | [
"GO:0006810",
"GO:0006811",
"GO:0006820",
"GO:0006821",
"GO:0006996",
"GO:0008150",
"GO:0009657",
"GO:0009668",
"GO:0009987",
"GO:0010027",
"GO:0010109",
"GO:0015698",
"GO:0016043",
"GO:0019222",
"GO:0034220",
"GO:0042548",
"GO:0043467",
"GO:0050789",
"GO:0050794",
"GO:0051179"... | [
"GO:0006810",
"GO:0006811",
"GO:0006820",
"GO:0006821",
"GO:0006996",
"GO:0008150",
"GO:0009657",
"GO:0009668",
"GO:0009987",
"GO:0010027",
"GO:0010109",
"GO:0015698",
"GO:0016043",
"GO:0019222",
"GO:0034220",
"GO:0042548",
"GO:0043467",
"GO:0050789",
"GO:0050794",
"GO:0051179"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0009507",
"GO:0009526",
"GO:0009534",
"GO:0009535",
"GO:0009536",
"GO:0009579",
"GO:0016020",
"GO:0019867",
"GO:0031090",
"GO:0031967",
"GO:0031968",
"GO:0031976",
"GO:0034357",
"GO:0042170",
"GO:0042651",
"GO:0043226",
"GO:0043227",
"GO:0043228"... | AF-Q8GX93-F1-model_v6.pdb | 3702.Q8GX93 | [
"P60300",
"Q9FWX6",
"P92943",
"Q96282",
"Q9SVV6",
"P92942",
"O80832",
"Q9M1T1",
"Q9FFE9",
"Q93YS0",
"Q9LK65",
"Q9M2D2",
"Q9ZS89",
"Q84WB2"
] | [
"IPR050368",
"IPR046342",
"IPR014743",
"IPR000644",
"IPR001807"
] | {"IPR014743": [76, 499], "IPR046342": [557, 702], "IPR050368": [68, 699], "IPR001807": [143, 497], "IPR000644": [561, 696]} | - Chloride channel protein CLC-d
- Chloride channel protein CLC-c
- Chloride channel protein CLC-b
- Putative chloride channel-like protein CLC-g
- Chloride channel protein CLC-a
- K(+) efflux antiporter 3, chloroplastic
- Two-pore potassium channel 3
- Voltage-dependent chloride channel 1, chloroplastic
- Putative DUF... | - IPR050368: Voltage-gated ClC-type chloride channel (family) [68-699]
- IPR046342: CBS domain superfamily (homologous_superfamily) [557-702]
- IPR014743: Chloride channel, core (homologous_superfamily) [76-499]
- IPR000644: CBS domain (domain) [561-696]
- IPR001807: Chloride channel (family) [143-497] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0016740 (transferase activity), GO:0003676 (nucleic acid binding), GO:0016772 (transferase activity, transferring ... |
P76290 | Carboxy-S-adenosyl-L-methionine synthase | Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) | Escherichia coli (strain K12) | 247 | null | MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGALVLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHNAGFEHSELWFQCFNFGSLVALKAEDAA | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0042802",
"GO:0042803",
"GO:0046983"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0042802",
"GO:0042803",
"GO:0046983"
] | [] | AF-P76290-F1-model_v6.pdb | 511145.b1870 | [
"Q2MAF5",
"Q2MB08",
"Q2M8S7",
"Q2M7S0",
"P77586",
"P76291"
] | [
"IPR041698",
"IPR029063",
"IPR005271"
] | {"IPR029063": [18, 247], "IPR005271": [1, 243], "IPR041698": [60, 158]} | - tRNA U34 carboxymethyltransferase
- tRNA 5-carboxymethoxyuridine methyltransferase
- Inner membrane protein YecN
- tRNA1(Val) (adenine(37)-N6)-methyltransferase
- tRNA (cytidine(34)-2'-O)-methyltransferase
- Thiazole synthase | - IPR041698: Methyltransferase domain 25 (domain) [60-158]
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [18-247]
- IPR005271: Carboxy-S-adenosyl-L-methionine synthase (family) [1-243] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016741 (transferase activity, transferring one-carbon groups), GO:0008168 (methyltransferase activity), GO:0008757 (S-adenosylmethionine-d... |
Q6P4Q7 | Metal transporter CNNM4 | Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function | Homo sapiens (Human) | 775 | Cell membrane; Multi-pass membrane protein | MAPVGGGGRPVGGPARGRLLLAAPVLLVLLWALGARGQGSPQQGTIVGMRLASCNKSCGTNPDGIIFVSEGSTVNLRLYGYSLGNISSNLISFTEVDDAETLHKSTSCLELTKDLVVQQLVNVSRGNTSGVLVVLTKFLRRSESMKLYALCTRAQPDGPWLKWTDKDSLLFMVEEPGRFLPLWLHILLITVLLVLSGIFSGLNLGLMALDPMELRIVQNCGTEKERRYARKIEPIRRKGNYLLCSLLLGNVLVNTSLTILLDNLIGSGLMAVASSTIGIVIFGEILPQALCSRHGLAVGANTILLTKFFMLLTFPLSFPI... | [
"GO:0006873",
"GO:0008150",
"GO:0019725",
"GO:0030003",
"GO:0042592",
"GO:0048878",
"GO:0050801",
"GO:0055080",
"GO:0055082"
] | [
"GO:0006873",
"GO:0008150",
"GO:0019725",
"GO:0030003",
"GO:0042592",
"GO:0048878",
"GO:0050801",
"GO:0055080",
"GO:0055082"
] | [] | [] | AF-Q6P4Q7-F1-model_v6.pdb | 9606.ENSP00000366275 | [
"Q6DKT9",
"P0DN79",
"Q93096",
"Q8IVJ1",
"P49915",
"R4GN50",
"H7C2H4",
"Q9Y6N1"
] | [
"IPR018490",
"IPR046342",
"IPR044751",
"IPR014710",
"IPR000644",
"IPR000595",
"IPR045095",
"IPR057492",
"IPR002550"
] | {"IPR046342": [359, 511], "IPR018490": [579, 718], "IPR014710": [588, 732], "IPR045095": [154, 736], "IPR057492": [46, 175], "IPR002550": [178, 358], "IPR044751": [372, 501], "IPR000644": [445, 511], "IPR000595": [575, 652]} | - Cystathionine beta-synthase
- Cytochrome c oxidase assembly protein COX11, mitochondrial
- Protein tyrosine phosphatase type IVA 2
- Protein tyrosine phosphatase type IVA 1
- Matrix metalloproteinase-20
- Solute carrier family 41 member 1
- GMP synthase [glutamine-hydrolyzing] | - IPR018490: Cyclic nucleotide-binding domain superfamily (homologous_superfamily) [579-718]
- IPR046342: CBS domain superfamily (homologous_superfamily) [359-511]
- IPR044751: Ion transporter-like, CBS domain (domain) [372-501]
- IPR014710: RmlC-like jelly roll fold (homologous_superfamily) [588-732]
- IPR000644: CBS ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0051179 (localization), GO:0042592 (homeostatic process), GO:0051234 (establishment of localization), GO:0048878 (... |
Q20754 | Cuticle collagen 38 | Probable cuticular collagen-like protein (Probable). Nematode cuticles are composed largely of collagen-like proteins (Probable). The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (Probable). Acts downstream of the Wnt signaling pathway, perhaps in the formation of t... | Caenorhabditis elegans | 287 | Nucleus | MSKYLVPVCASISLVAVFGALVAMHSIVVDIDTMREEIVTGVHDMKVMSDDAWNRMIGFTKPSLDSESRSAAFASVFRNKRSAYPSQCNCDANSQGCPPGPPGPPGLPGGRGDQGPSGDKGRDGASGVSLAVTHHLPGGCIQCPQGPPGETGPDGDIGEPGFPGASGSAGQCGEDGAPGEAGITGEQGPQGEPGTEGSEGPTGQDGTIGGPGLPGQPGTPGWPGSQGEPGKNGDSGVDGEQGPQGPQGPDGQPGRDADNGQPGLPGKDGSIGPDANYCPCPARAKKH | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [] | [] | AF-Q20754-F1-model_v6.pdb | 6239.F54C9.4.1 | [
"Q9N4U2",
"O61738",
"P91248",
"O18062",
"Q9TXZ7",
"Q23262",
"Q9XWB4",
"A3QM98",
"Q9XW38",
"O44989",
"Q18480"
] | [
"IPR008160",
"IPR002486"
] | {"IPR002486": [4, 56], "IPR008160": [215, 273]} | - Nematode cuticle collagen N-terminal domain-containing protein
- Cuticle collagen 49
- Nematode cuticle collagen N-terminal domain-containing protein
- Protein dao-4
- Cuticle collagen 71
- Nematode Specific Peptide family
- DUF229 domain-containing protein
- COLlagen
- Venom protein
- Major sperm protein | - IPR008160: Collagen triple helix repeat (repeat) [215-273]
- IPR002486: Nematode cuticle collagen, N-terminal (domain) [4-56] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0042302 (structural constituent of cuticle)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structur... |
O44989 | Cuticle collagen 49 | Probable cuticular collagen-like protein (Probable). Nematode cuticles are composed largely of collagen-like proteins (Probable). The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (Probable). Acts downstream of the Wnt signaling pathway, perhaps in the formation of t... | Caenorhabditis elegans | 283 | null | MWKFVIGSVSTAAFFVSVCTIYFSVSMLDELDSFRLSIRDELEDWKEVSDDTWQRLNDMTSRNVPKKTNILKEFVRGKRNVGNDQCNCAEPTKNCPAGPPGEKGSLGNPGQPGPDGVDGDNGVDGDVVIHDMPNPKECIKCPAGPPGPPGPPGPLGPRGDKGPSGPRGALGDQGETGPVGEIGDQGPPGSAGRAGPRGQAGQPGTIAIVGLAGRPGPQGPLGEPGAQGEPGVDGKDGALGAPGRKAENGRPGKRGKDGVAGVPGTRGKEGEDAGYCTCPPRTA | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [] | [] | AF-O44989-F1-model_v6.pdb | 6239.K09H9.3.1 | [
"Q9XXF1",
"Q9XW38",
"G5EDV0",
"Q18480",
"P91248",
"Q9N4U2",
"Q20754",
"A3QM98",
"O01904",
"Q23262",
"Q9TXZ7",
"O18062"
] | [
"IPR008160",
"IPR002486"
] | {"IPR002486": [3, 56], "IPR008160": [213, 271]} | - Cuticle collagen 71
- Nematode cuticle collagen N-terminal domain-containing protein
- Cuticle collagen 38
- Protein dao-4
- CPG4 domain-containing protein
- Nematode cuticle collagen N-terminal domain-containing protein
- Nematode cuticle collagen N-terminal domain-containing protein
- COLlagen
- Venom protein
- Nem... | - IPR008160: Collagen triple helix repeat (repeat) [213-271]
- IPR002486: Nematode cuticle collagen, N-terminal (domain) [3-56] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005198 (structural molecule activity), GO:0042302 (structural constituent of cuticle)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structur... |
Q9N4U2 | Cuticle collagen 71 | Probable cuticular collagen-like protein (Probable). Nematode cuticles are composed largely of collagen-like proteins (Probable). The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (Probable). Acts downstream of the Wnt signaling pathway, perhaps in the formation of t... | Caenorhabditis elegans | 371 | Membrane; Single-pass membrane protein. Nucleus | MRNAGGDKPFSTPVLLREMGLKTHVDDDPKTKAYRLIGYAAVTFSTVSVICFCVTMPVVFTYVQSVKRQMSHEMATCNVNARQIFDDVAALRAGFPFAQAGNRTARQAGYDVHPSKPTPVGYSGGDAAAAEVKGNSPAAAYEDKPFVAVGVEEGPHTATTGSDSEGTCHDCCLPGPPGPPGPPGRPGPNGKAGANGLNGNPGRPPEAPCEPVTPPPCPPCPAGPKGAPGQAGYPGADGQPGSQGDNGEKGSDGAAGEKGRPGPLGKIGEPGATGETGENAENSEPTPGPQGPPGAIGPVGSRGTPGHPGEDGEAGAPGAP... | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [] | [] | AF-Q9N4U2-F1-model_v6.pdb | 6239.Y49F6B.10.1 | [
"Q18480",
"O44989",
"Q09419",
"Q18065",
"Q9XW38",
"G5EDV0",
"A3QM98",
"Q20754",
"Q9XWB4",
"O18062",
"Q23262",
"Q9TXZ7",
"O76655",
"Q23447",
"O16467",
"O61738"
] | [
"IPR008160",
"IPR002486"
] | {"IPR002486": [36, 88], "IPR008160": [223, 281]} | - Cuticle collagen 49
- Nematode cuticle collagen N-terminal domain-containing protein
- Protein dao-4
- Cuticle collagen 38
- Prion-like-(Q/N-rich)-domain-bearing protein
- CPG4 domain-containing protein
- Nematode cuticle collagen N-terminal domain-containing protein
- Nematode Specific Peptide family
- Venom protein... | - IPR008160: Collagen triple helix repeat (repeat) [223-281]
- IPR002486: Nematode cuticle collagen, N-terminal (domain) [36-88] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0032501 (multicellular organismal process), GO:0048856 (anatomical structure development), GO:0007275 (multicellul... |
Q7NWF2 | Arginine ADP-riboxanase CopC | ADP-riboxanase effector that inhibits host cell programmed cell death. Acts by mediating arginine ADP-riboxanation of host caspases (CASP3, CASP7, CASP8 and CASP9), blocking their processing and activation. ADP- riboxanation of host apoptotic caspases (CASP3, CASP7, CASP8 and CASP9) prevents their activation, thereby i... | Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / CCUG | 487 | Secreted. Host cytoplasm. Note=Secreted via the type III secretion system (T3SS) | MRVENHSPSLSKLNPPEAGSGDPTAIGRRLSGIRRAPLPHVSAGSDGEAAAAGKIGAFLRKAVAAQSYGLMFANGKLFEATGDALEKRGQYGFSALQRLDGLSRRNLAAVEARLGALDSAERGLKERIMTGAWHFRHQSNAALDDGKTAAIASNHLLARESRSSGGNTFAGDKALLSNHDFVFFGVEFSGRGKQDKPLNHKHSTMDFGANAYVVPDTLPACRHGYLTLTDHFFNRVPGGREAEHQDFVGSFPQMGAETGRWIHEGKYRQNAPIFNYRDMKAAVALHLIEFLRDSKDAAFKAYVFDQAMQSGQALDRVLNS... | [
"GO:0006915",
"GO:0006950",
"GO:0006952",
"GO:0006954",
"GO:0007154",
"GO:0007165",
"GO:0007166",
"GO:0008150",
"GO:0008152",
"GO:0008219",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0012501",
"GO:0019538",
"GO:0023052",
"GO:0031347",
"GO:0031349",
"GO:0032101"... | [
"GO:0006915",
"GO:0006950",
"GO:0006952",
"GO:0006954",
"GO:0007154",
"GO:0007165",
"GO:0007166",
"GO:0008150",
"GO:0008152",
"GO:0008219",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0012501",
"GO:0019538",
"GO:0023052",
"GO:0031347",
"GO:0031349",
"GO:0032101"... | [] | [] | AF-Q7NWF2-F1-model_v6.pdb | 243365.CV_2038 | null | [
"IPR010366",
"IPR036770",
"IPR002110"
] | {"IPR036770": [343, 479], "IPR010366": [193, 470], "IPR002110": [444, 476]} | - IPR010366: Arginine ADP-riboxanase OspC1-4 (family) [193-470]
- IPR036770: Ankyrin repeat-containing domain superfamily (homologous_superfamily) [343-479]
- IPR002110: Ankyrin repeat (repeat) [444-476] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016829 (lyase activity), GO:0016840 (carbon-nitrogen lyase activity), GO:0016772 (transferase activity, transferring phosphorus-containi... | |
Q8WNR0 | High affinity copper uptake protein 1 | [High affinity copper uptake protein 1]: Uniporter that mediates the transport of copper(1+) from the extracellular space to the cytoplasm, across the plasma membrane and delivers directly copper(1+) to specific chaperone such as ATOX1, via a copper(1+)- mediated transient interaction between the C-terminal domain and ... | Sus scrofa (Pig) | 189 | Cell membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note... | MDHSAHMGMSTHMGMSDMNHSTTMPPSHHHPTSSGSHESMMMPMTFYFGFKKVEVLFAGLVINTAGEMAGAFVAVFLLAMFYEGLKIAREGLLRKSQVSIRYNSMPVPGPNGTILMETHKTVGQQMLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKAVVVDITEHCH | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0016324",
"GO:0045177",
"GO:0071944",
"GO:0098590",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0016324",
"GO:0045177",
"GO:0071944",
"GO:0098590",
"GO:0110165"
] | AF-Q8WNR0-F1-model_v6.pdb | 9823.ENSSSCP00000044266 | [
"P81045",
"A0A287A861",
"A0A287B262",
"Q95245",
"K7GT44"
] | [
"IPR007274"
] | {"IPR007274": [33, 187]} | - P-type Cu(+) transporter
- Copper transport protein ATOX1
- Copper-transporting ATPase 1
- Cytochrome c oxidase copper chaperone
- Transmembrane ascorbate-dependent reductase CYB561 | - IPR007274: Ctr copper transporter (family) [33-187] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0005515 (protein binding), GO:0015075 (monoatomic ion transmembrane transporter activity), GO:0015318 (inorganic molecular entity transmembrane transport... |
Q9SQ68 | NADPH-dependent codeinone reductase 1-3 | NADPH-dependent codeinone reductase involved in biosynthesis of morphinan-type benzylisoquinoline and opiate alkaloids natural products. Reduces codeinone to codeine in the penultimate step in morphine biosynthesis. Can use morphinone, hydrocodone and hydromorphone as substrate during reductive reaction with NADPH as c... | Papaver somniferum (Opium poppy) | 321 | Cytoplasm, cytosol. Note=Present in the cytosolic part of laticifer cells that secrete latex. Localized to the parietal region of the sieve element cytoplasm | MESNGVPMITLSSGIRMPALGMGTAETMVKGTEREKLAFLKAIEVGYRHFDTAAAYQSEECLGEAIAEALQLGLIKSRDELFITSKLWCADAHADLVLPALQNSLRNLKLDYLDLYLIHHPVSLKPGKFVNEIPKDHILPMDYKSVWAAMEECQTLGFTRAIGVCNFSCKKLQELMAAAKIPPVVNQVEMSPTLHQKNLREYCKANNIMITAHSVLGAICAPWGSNAVMDSKVLHQIAVARGKSVAQVSMRWVYQQGASLVVKSFNEGRMKENLKIFDWELTAENMEKISEIPQSRTSSADFLLSPTGPFKTEEEFWDEK... | [
"GO:0008150",
"GO:0008152",
"GO:0009820",
"GO:0009987",
"GO:0033076",
"GO:0071272",
"GO:2001291"
] | [
"GO:0008150",
"GO:0008152",
"GO:0009820",
"GO:0009987",
"GO:0033076",
"GO:0071272",
"GO:2001291"
] | [] | [] | AF-Q9SQ68-F1-model_v6.pdb | null | null | [
"IPR023210",
"IPR018170",
"IPR020471",
"IPR036812",
"IPR044497"
] | {"IPR036812": [7, 321], "IPR020471": [8, 298], "IPR044497": [13, 294], "IPR023210": [20, 292], "IPR018170": [46, 276]} | - IPR023210: NADP-dependent oxidoreductase domain (domain) [20-292]
- IPR018170: Aldo/keto reductase, conserved site (conserved_site) [46-276]
- IPR020471: Aldo-keto reductase (family) [8-298]
- IPR036812: NAD(P)-dependent oxidoreductase domain superfamily (homologous_superfamily) [7-321]
- IPR044497: Aldo-keto reducta... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (B... | |
B9VRJ2 | NADPH-dependent codeinone reductase 1-5 | NADPH-dependent codeinone reductase involved in biosynthesis of morphinan-type benzylisoquinoline and opiate alkaloids natural products. Reduces codeinone to codeine in the penultimate step in morphine biosynthesis. Can use morphinone, hydrocodone and hydromorphone as substrate during reductive reaction with NADPH as c... | Papaver somniferum (Opium poppy) | 321 | Cytoplasm, cytosol. Note=Present in the cytosolic part of laticifer cells that secrete latex | MESNGVPMITLSSGIRMPALGMGTVETMEKGTEREKLAFLKAIEVGYRHFDTAAAYQTEECLGEAIAEALQLGLIKSRDELFITSKLWCADAHADLVLPALQNSLRNLKLDYLDLYLIHHPVSLKPGKFVNEIPKDHILPMDYKSVWAAMEECQTLGFTRAIGVCNFSCKKLQELMATANSPPVVNQVEMSPTLHQKNLREYCKANNIMITAHSVLGAVGAAWGTKAVMHSKVLHQIAVARGKSVAQVSMRWVYQQGASLVVKSFNEARMKENLKIFDWELTAEDMEKISEIPQSRTSSAAFLLSPTGPFKTEEEFWDEK... | [
"GO:0003674",
"GO:0003824",
"GO:0016491",
"GO:0016614",
"GO:0016616",
"GO:0047036"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016491",
"GO:0016614",
"GO:0016616",
"GO:0047036"
] | [] | AF-B9VRJ2-F1-model_v6.pdb | null | null | [
"IPR023210",
"IPR018170",
"IPR020471",
"IPR036812",
"IPR044497"
] | {"IPR036812": [6, 321], "IPR020471": [8, 300], "IPR044497": [13, 294], "IPR023210": [20, 292], "IPR018170": [46, 276]} | - IPR023210: NADP-dependent oxidoreductase domain (domain) [20-292]
- IPR018170: Aldo/keto reductase, conserved site (conserved_site) [46-276]
- IPR020471: Aldo-keto reductase (family) [8-300]
- IPR036812: NAD(P)-dependent oxidoreductase domain superfamily (homologous_superfamily) [6-321]
- IPR044497: Aldo-keto reducta... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Biological Process (B... | |
Q9Y6N1 | Cytochrome c oxidase assembly protein COX11, mitochondrial | Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I | Homo sapiens (Human) | 276 | Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side | MGGLWRPGWRCVPFCGWRWIHPGSPTRAAERVEPFLRPEWSGTGGAERGLRWLGTWKRCSLRARHPALQPPRRPKSSNPFTRAQEEERRRQNKTTLTYVAAVAVGMLGASYAAVPLYRLYCQTTGLGGSAVAGHASDKIENMVPVKDRIIKISFNADVHASLQWNFRPQQTEIYVVPGETALAFYRAKNPTDKPVIGISTYNIVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMIKVDLITLSYTFFEAKEGHKLPVPGYN | [
"GO:0006139",
"GO:0006163",
"GO:0006164",
"GO:0006753",
"GO:0006754",
"GO:0006793",
"GO:0006796",
"GO:0006873",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009117",
"GO:0009141",
"GO:0009142",
"GO:0009144",
"GO:0009145",
"GO:0009150",
"GO:0009152",
"GO:0009165",
"GO:0009201"... | [
"GO:0006139",
"GO:0006163",
"GO:0006164",
"GO:0006753",
"GO:0006754",
"GO:0006793",
"GO:0006796",
"GO:0006873",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009117",
"GO:0009141",
"GO:0009142",
"GO:0009144",
"GO:0009145",
"GO:0009150",
"GO:0009152",
"GO:0009165",
"GO:0009201"... | [] | [] | AF-Q9Y6N1-F1-model_v6.pdb | 9606.ENSP00000299335 | [
"Q9BUK0",
"Q9UPH2",
"Q37526",
"Q9Y6M7",
"Q9UK87",
"Q5T8T4",
"O75880",
"Q969F7",
"Q14Y83",
"Q9BU25",
"Q49B96",
"Q5W0E8",
"Q34770",
"Q9UNX3",
"Q56AP3",
"Q9NT45",
"Q6IPY2",
"Q9BUY8",
"Q9NTN0",
"O15405",
"Q96MB3",
"Q9NRN1",
"Q3MHD6",
"Q96BV4",
"Q8N8Q8",
"Q5JTJ4",
"Q86... | [
"IPR023471",
"IPR007533"
] | {"IPR023471": [140, 272], "IPR007533": [75, 273]} | - Protoheme IX farnesyltransferase, mitochondrial
- Cytochrome c oxidase subunit 2
- Cytochrome c oxidase subunit 3
- Cytochrome c oxidase subunit 1
- Protein SCO1 homolog, mitochondrial
- Cytochrome c oxidase copper chaperone
- Heme A synthase COX15
- Protein SCO2 homolog, mitochondrial
- Surfeit locus protein 1
- Cyt... | - IPR023471: Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily (homologous_superfamily) [140-272]
- IPR007533: Cytochrome c oxidase assembly protein CtaG/Cox11 (family) [75-273] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0009055 (electron transfer activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:00... |
Q1ZXH9 | Probable lanosterol 14-alpha demethylase | Sterol 14alpha-demethylase that plays a critical role in the third module of ergosterol biosynthesis pathway, being ergosterol the major sterol component in cell membranes that participates in a variety of functions. Starting from lanosterol (lanosta-8,24-dien-3beta-ol), it catalyzes the three-step oxidative removal of... | Dictyostelium discoideum (Social amoeba) | 466 | Membrane | MIGTIAVLVIAILVIFAFKKSPSNIPPIVETIPFIGCFYQFAKNPLQLVRNSYDRLGEIFTLHLMGFKMTFVLGPEAQALFFRGTDEELSPKEAYRFVTPVFGKGVVYDSETEIMYEQLRFVKNGLVLSQLKKAVGIIQEETEKYFETKWGDSGEIDLLYEMNKLTILTASRCLMGKSINKSLGQSGQLADLYHELEEGLNPISFFFPNLPLPSFKKRDAARAKVAAIFHSIIQERRRSTDDSVDDVLYTLMNSKYKDGSVLEDEQIVGLMIGLLFAGQHTSSITLTYTIFYLLNNLEYFDETQKDINDIVQKENQGEIN... | [
"GO:0008150",
"GO:0042221",
"GO:0050896",
"GO:1901698",
"GO:1902351"
] | [
"GO:0008150",
"GO:0042221",
"GO:0050896",
"GO:1901698",
"GO:1902351"
] | [] | [] | AF-Q1ZXH9-F1-model_v6.pdb | 44689.Q1ZXH9 | [
"Q55D53",
"Q55GJ9",
"Q54WK0",
"Q55ET6",
"Q54BK7",
"Q55EU7",
"Q86AK4",
"Q54FQ6",
"Q9NDE9",
"Q9NH02",
"Q54XV1",
"Q55CT7",
"Q54I19",
"Q54L85",
"Q54XP1",
"Q55GP8",
"Q86HU8",
"Q54IE9",
"Q54E72",
"Q54IW3",
"Q54PP1",
"Q54TU9",
"Q55D54",
"Q54VU3",
"Q54DR1",
"Q9U641",
"Q54... | [
"IPR050529",
"IPR017972",
"IPR001128",
"IPR036396",
"IPR002403"
] | {"IPR036396": [17, 466], "IPR050529": [3, 465], "IPR002403": [25, 431], "IPR001128": [26, 454], "IPR017972": [406, 415]} | - Cycloartenol synthase
- Squalene synthase
- Delta(14)-sterol reductase
- Delta(14)-sterol reductase
- Protein erg2 homolog
- Squalene monooxygenase
- Cycloeucalenol cycloisomerase
- Putative methylsterol monooxygenase DDB_G0270946
- Sterol desaturase family protein
- Putative methylsterol monooxygenase DDB_G0269788 | - IPR050529: Cytochrome P450, sterol 14-alpha demethylase (family) [3-465]
- IPR017972: Cytochrome P450, conserved site (conserved_site) [406-415]
- IPR001128: Cytochrome P450 (family) [26-454]
- IPR036396: Cytochrome P450 superfamily (homologous_superfamily) [17-466]
- IPR002403: Cytochrome P450, E-class, group IV (fa... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen), GO:0004497 (monooxygenase activity), GO:0016709 (oxidoreductase activity, a... |
Q6NWC6 | Cleavage and polyadenylation specificity factor subunit 6 | Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so c... | Danio rerio (Zebrafish) (Brachydanio rerio) | 545 | Nucleus. Nucleus, nucleoplasm. Nucleus speckle. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm | MADGVDHIDIYADVEEEFNQESDYPVHDQIDLYDDVISPSANNGDAPEDRDYLDSLPAPGGNEGSKGAPANVVYTYNGKRIALYIGNLTWWTTDEDLTDAIRSIGINDVLEIKFFENRANGQSKGFALVCVGSDSSSRKLMDLLSKRELHGQNPIVTPCNKQSLSQFEMQSRKSTQSGQMSGEGKAGPPGSGSRGGGFPPGKGQRRFPGPPGQGDRFPGPVGPGGPPPHFPGMQGPPRLPSGPPGPLGPPGPPPPGQGLPPPLGGPPNRGDRPPPPVLFPGQFGQPPMGPMPPGPPPPGYGPPPGPPPPQQGPPPPGPFP... | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0016604",
"GO:0031974",
"GO:0031981",
"GO:0035770",
"GO:0042382",
"GO:0043226",
"GO:0043227",
"GO:0043228",
"GO:0043229",
"GO:0043231",
"GO:0043232",
"GO:0043233",
"GO:0070013",
"GO:0099080",
"GO:0110165",
"GO:0140168"... | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005654",
"GO:0016604",
"GO:0031974",
"GO:0031981",
"GO:0035770",
"GO:0042382",
"GO:0043226",
"GO:0043227",
"GO:0043228",
"GO:0043229",
"GO:0043231",
"GO:0043232",
"GO:0043233",
"GO:0070013",
"GO:0099080",
"GO:0110165",
"GO:0140168"... | AF-Q6NWC6-F1-model_v6.pdb | 7955.ENSDARP00000076726 | [
"A0A0G2KIQ1",
"Q6PH14",
"Q5XJD3",
"F1QVV4",
"A0A0R4I9D6",
"F1QIB2",
"Q6PC19",
"Q7ZV69",
"Q5U3T4",
"F1Q7H6",
"A0A0R4IC37",
"A0A0R4IU36",
"Q7ZV13",
"Q7T3C6",
"F1QVD2",
"U3JAJ0",
"F1QGD0",
"Q4V8Q5",
"B8JMA3",
"Q6P022",
"F1QWP0",
"F1Q949",
"A0A0R4IAI1",
"F1QFK9"
] | [
"IPR035979",
"IPR034769",
"IPR034772",
"IPR057951",
"IPR000504",
"IPR012677"
] | {"IPR012677": [81, 172], "IPR035979": [83, 187], "IPR034772": [1, 273], "IPR000504": [81, 161], "IPR034769": [82, 158], "IPR057951": [405, 509]} | - Cleavage and polyadenylation specificity factor subunit 5
- Serine and arginine-rich-splicing factor 7b
- Cleavage stimulation factor subunit 1
- Cleavage and polyadenylation specificity factor subunit 2
- Cleavage and polyadenylation specificity factor subunit 1
- Splicing factor U2AF subunit
- Symplekin
- Cleavage ... | - IPR035979: RNA-binding domain superfamily (homologous_superfamily) [83-187]
- IPR034769: Cleavage and polyadenylation specificity factor subunit 6, RNA recognition motif (domain) [82-158]
- IPR034772: CPSF6/7 (family) [1-273]
- IPR057951: CPSF6/7, RSLD domain, N-terminal region (domain) [405-509]
- IPR000504: RNA rec... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding), GO:0003730 (mRNA 3'-UTR binding)
Biological Process (BP): GO:0... |
P24251 | Sigma factor-binding protein Crl | Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes, such as the csgBAC operon encoding the subunits of curli proteins. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 (rpoD) and sigma-32 (rpoH) | Escherichia coli (strain K12) | 133 | Cytoplasm | MTLPSGHPKSRLIKKFTALGPYIREGKCKDNRFFFDCLAVCVNVKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLREFHEKLRELLTTLNLKLEPADDFRDEPVKLTA | [
"GO:0006355",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010604",
"GO:0016043",
"GO:0019219",
"GO:0019222",
"GO:0022607",
"GO:0043933",
"GO:0044085",
"GO:0045893",
"GO:0048518",
"GO:0048522",
"GO:0050789"... | [
"GO:0006355",
"GO:0008150",
"GO:0009889",
"GO:0009891",
"GO:0009893",
"GO:0009987",
"GO:0010468",
"GO:0010556",
"GO:0010557",
"GO:0010604",
"GO:0016043",
"GO:0019219",
"GO:0019222",
"GO:0022607",
"GO:0043933",
"GO:0044085",
"GO:0045893",
"GO:0048518",
"GO:0048522",
"GO:0050789"... | [
"GO:0003674",
"GO:0005488",
"GO:0005515"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-P24251-F1-model_v6.pdb | null | null | [
"IPR009986",
"IPR038208"
] | {"IPR038208": [1, 133], "IPR009986": [1, 128]} | - IPR009986: Sigma factor-binding transcriptional regulator Crl (family) [1-128]
- IPR038208: Sigma factor-binding protein Crl superfamily (homologous_superfamily) [1-133] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0051540 (metal cluster binding), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity), GO:0016705 (oxidoreductase activity, acting on paired donors, with... | |
P0DSV7 | Cytokine response-modifying protein B | Inhibits host immune defense by binding to host TNF and various chemokines in the extracellular space. Binds host CC chemokines (beta chemokines) and CXC chemokines (alpha chemokines) | Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus) | 349 | Secreted | MKSVLYLYILFLSCIIINGRDAAPYTPPNGKCKDTEYKRHNLCCLSCPPGTYASRLCDSKTNTQCTPCGSGTFTSRNNHLPACLSCNGRCNSNQVETRSCNTTHNRICECSPGYYCLLKGSSGCKACVSQTKCGIGYGVSGHTSVGDVICSPCGFGTYSHTVSSADKCEPVPNNTFNYIDVEITLYPVNDTSCTRTTTTGLSESILTSELTITMNHTDCNPVFREEYFSVLNKVATSGFFTGENRYQNISKVCTLNFEIKCNNKGSSFKQLTKAKNDDGMMSHSETVTLAGDCLSSVDIYILYSNTNAQDYETDTISYRV... | [
"GO:0002376",
"GO:0006915",
"GO:0006950",
"GO:0006952",
"GO:0006955",
"GO:0007154",
"GO:0007165",
"GO:0007166",
"GO:0008150",
"GO:0008219",
"GO:0009605",
"GO:0009607",
"GO:0009615",
"GO:0009987",
"GO:0012501",
"GO:0019221",
"GO:0023052",
"GO:0033209",
"GO:0034097",
"GO:0034612"... | [
"GO:0002376",
"GO:0006915",
"GO:0006950",
"GO:0006952",
"GO:0006955",
"GO:0007154",
"GO:0007165",
"GO:0007166",
"GO:0008150",
"GO:0008219",
"GO:0009605",
"GO:0009607",
"GO:0009615",
"GO:0009987",
"GO:0012501",
"GO:0019221",
"GO:0023052",
"GO:0033209",
"GO:0034097",
"GO:0034612"... | [
"GO:0003674",
"GO:0004888",
"GO:0005031",
"GO:0005035",
"GO:0038023",
"GO:0060089"
] | [
"GO:0005575",
"GO:0005576",
"GO:0005615",
"GO:0110165"
] | null | null | null | [
"IPR001368",
"IPR011172",
"IPR034059",
"IPR051670",
"IPR010806"
] | {"IPR011172": [5, 338], "IPR051670": [22, 201], "IPR001368": [31, 150], "IPR034059": [32, 154], "IPR010806": [172, 313]} | - IPR001368: TNFR/NGFR cysteine-rich region (domain) [31-150]
- IPR011172: Poxvirus, TNF-alpha receptor-II (family) [5-338]
- IPR034059: Tumor necrosis factor receptor, N-terminal, viral (domain) [32-154]
- IPR051670: TNF and chemokine receptor-like (family) [22-201]
- IPR010806: Poxvirus, TNF receptor-II, C-terminal (... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0048583 (re... | |
Q0IIP8 | C-reactive protein | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis, and complement fixation through its calcium-dependent binding to phosphorylcholine | Danio rerio (Zebrafish) (Brachydanio rerio) | 225 | Secreted | MLVVFLCLLSVTLEATEGFKNLSGKVLQFKTATDNSYVKLYPEKPLSLSAFTLCMRVATELPLDREVILFAYYTPDVDELNVWRERDGRVSLYIQSSKDAAFFRLPPLSTLQTHLCVAWESATGLTAFWMDGRRSLHQVYRKGYSIRSGGTVVLGQDPDSYVGSFDVDQSFVGEIANLQMWDYVLSSAQIKAVYYNQDNRVKGNVFDWDTIEYDVTGNVLVATDN | [
"GO:0006950",
"GO:0006952",
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0009615",
"GO:0043207",
"GO:0044419",
"GO:0050896",
"GO:0051607",
"GO:0051707"
] | [
"GO:0006950",
"GO:0006952",
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0009615",
"GO:0043207",
"GO:0044419",
"GO:0050896",
"GO:0051607",
"GO:0051707"
] | [] | [] | AF-Q0IIP8-F1-model_v6.pdb | null | null | [
"IPR001759",
"IPR013320",
"IPR051005"
] | {"IPR013320": [21, 222], "IPR051005": [1, 222], "IPR001759": [19, 225]} | - IPR001759: Pentraxin domain (domain) [19-225]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [21-222]
- IPR051005: Pentraxin domain-containing protein (family) [1-222] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:0097159 (organic cyclic compound binding), GO:0008289 (lipid binding), GO:0043178 (alcohol binding), GO:0005496 (steroid binding), GO:0032934 (sterol binding), GO:0015485 (cholesterol binding)
Biologi... | |
P21334 | Phytoene desaturase | Phytoene desaturase involved in the carotenoid biosynthesis pathway. Converts phytoene into 3,4-didehydrolycopene via the intermediates phytofluene, zeta-carotene, neurosporene and lycopene, by introducing up to five double bonds into phytoene. Is also able to desaturate 1-hydroxyneurosporene into 1-hydroxylycopene and... | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / | 595 | Membrane; Single-pass membrane protein | MAETQRPRSAIIVGAGAGGIAVAARLAKAGVDVTVLEKNDFTGGRCSLIHTKAGYRFDQGPSLLLLPGLFRETFEDLGTTLEQEDVELLQCFPNYNIWFSDGKRFSPTTDNATMKVEIEKWEGPDGFRRYLSWLAEGHQHYETSLRHVLHRNFKSILELADPRLVVTLLMALHPFESIWHRAGRYFKTDRMQRVFTFATMYMGMSPFDAPATYSLLQYSELAEGIWYPRGGFHKVLDALVKIGERMGVKYRLNTGVSQVLTDGGKNGKKPKATGVQLENGEVLNADLVVVNADLVYTYNNLLPKEIGGIKKYANKLNNRK... | [
"GO:0006629",
"GO:0006720",
"GO:0006721",
"GO:0008150",
"GO:0008152",
"GO:0008299",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016109",
"GO:0016114",
"GO:0016116",
"GO:0016117",
"GO:0042440",
"GO:0044238",
"GO:0046148",
"GO:0003674",
"GO:0003824",
"GO:0016166",
"GO:0016491"... | [
"GO:0006629",
"GO:0006720",
"GO:0006721",
"GO:0008150",
"GO:0008152",
"GO:0008299",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016109",
"GO:0016114",
"GO:0016116",
"GO:0016117",
"GO:0042440",
"GO:0044238",
"GO:0046148"
] | [
"GO:0003674",
"GO:0003824",
"GO:0016166",
"GO:0016491",
"GO:0016627"
] | [] | AF-P21334-F1-model_v6.pdb | 367110.P21334 | [
"Q1K4Y3",
"Q7RVN3",
"V5IKD8",
"Q86ZV1",
"A7UXI1",
"Q1K5X9",
"Q7S1P8",
"F5HHQ6",
"Q7S5Z0",
"Q7SET4"
] | [
"IPR036188",
"IPR008150",
"IPR014105",
"IPR002937"
] | {"IPR036188": [6, 511], "IPR014105": [10, 518], "IPR002937": [18, 294], "IPR008150": [481, 501]} | - Bifunctional lycopene cyclase/phytoene synthase
- Probable squalene synthase
- Geranylgeranyl pyrophosphate synthase
- Squalene/phytoene synthase
- Imidazole glycerol phosphate synthase hisHF
- 3-hydroxy-3-methylglutaryl coenzyme A reductase
- Carotenoid dioxygenase
- 4-hydroxybenzoate polyprenyltransferase, mitochon... | - IPR036188: FAD/NAD(P)-binding domain superfamily (homologous_superfamily) [6-511]
- IPR008150: Phytoene dehydrogenase, bacterial-type, conserved site (conserved_site) [481-501]
- IPR014105: Carotenoid/retinoid oxidoreductase (family) [10-518]
- IPR002937: Amine oxidase (domain) [18-294] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular proces... |
Q1L990 | Protein C19orf12 homolog | null | Danio rerio (Zebrafish) (Brachydanio rerio) | 141 | Mitochondrion. Mitochondrion membrane; Single-pass membrane protein. Endoplasmic reticulum. Cytoplasm, cytosol. Note=In response to oxidative stress, relocates to the cytosol forming aggregates that partially co-localize with mitochondria | MPPHVDDVMKLCCELSANQQVKTAVKQSGKGAAAAGGLAFAGGLIGGPLGIAVGGAVGGLLGCWMKSGQFKPLPQVIMELTPDQQARLYEDIVAILGSITWTDVAQLTALVMGNASLQQQVTAALLSYIHKELQAEVHYID | [
"GO:0007275",
"GO:0007399",
"GO:0007517",
"GO:0007519",
"GO:0008150",
"GO:0009888",
"GO:0009987",
"GO:0014706",
"GO:0014902",
"GO:0014904",
"GO:0022008",
"GO:0030154",
"GO:0030182",
"GO:0032501",
"GO:0032502",
"GO:0042692",
"GO:0048468",
"GO:0048513",
"GO:0048666",
"GO:0048699"... | [
"GO:0007275",
"GO:0007399",
"GO:0007517",
"GO:0007519",
"GO:0008150",
"GO:0009888",
"GO:0009987",
"GO:0014706",
"GO:0014902",
"GO:0014904",
"GO:0022008",
"GO:0030154",
"GO:0030182",
"GO:0032501",
"GO:0032502",
"GO:0042692",
"GO:0048468",
"GO:0048513",
"GO:0048666",
"GO:0048699"... | [] | [] | AF-Q1L990-F1-model_v6.pdb | 7955.ENSDARP00000076250 | null | [
"IPR033369"
] | {"IPR033369": [1, 140]} | - IPR033369: Protein C19orf12 (family) [1-140] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0042802 (identical protein binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0046914 (transition metal ion binding), GO:0005506 (iron ion binding)
Biological... | |
Q9M7I2 | B-type cell cycle switch protein ccs52A | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. Required to switch form cell proliferation to cell differentiation, endoreduplication and ploidy-dependent cell enlargem... | Medicago truncatula (Barrel medic) (Medicago tribuloides) | 475 | Nucleus. Note=Present in the nucleus of endoreduplication-competent cells | MDGTGNRNPPPTSTVGDNSPPPEPSPESLRHVSRMINSNHYTSPSRTIYSDRFIPSRSASKFALFDINTPTEGRDDSSSAYTTLLRTALFGPDVAGPVTPEKTDSPSMTLPNRNIFRYKTETRQSMHSLSPFMDDDFVPGINHSPVKAPRKVPRSPYKVLDAPALQDDFYLNLVDWSSHNVLAVGLGNCVYLWNACSSKVTKLCDLGVDDCVCSVGWAQRGTHLAVGTNNGKVQIWDAARCKKIRSMEGHRLRVGALAWSSSLLSSGGRDKNIYQRDIRTQEDFVSKLSGHKSEVCGLKWSYDNRELASGGNDNKLFVWN... | [
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0009624",
"GO:0043207",
"GO:0044419",
"GO:0050896",
"GO:0051707"
] | [
"GO:0008150",
"GO:0009605",
"GO:0009607",
"GO:0009624",
"GO:0043207",
"GO:0044419",
"GO:0050896",
"GO:0051707"
] | [] | [] | AF-Q9M7I2-F1-model_v6.pdb | 3880.Q9M7I2 | [
"G7JLB9",
"G7KWP0",
"G7JEI7",
"G7L7L4",
"A0A072TQ71",
"I3SVT4",
"G7K3C1",
"A0A072UMU0",
"G7IPZ9",
"A0A072UXR1",
"B7FH99",
"A0A072TYC9",
"G7JCB5",
"G7IA28",
"A0A072VD42",
"G7KSG1",
"G7K0X2",
"G7KTW0",
"G7K013",
"G7K6S4",
"A0A072V956",
"G7J2H6",
"G7KRU4",
"G7K258",
"G7I... | [
"IPR056150",
"IPR033010",
"IPR036322",
"IPR015943",
"IPR001680",
"IPR019775"
] | {"IPR015943": [146, 455], "IPR036322": [157, 457], "IPR033010": [38, 458], "IPR056150": [160, 449], "IPR019775": [437, 451], "IPR001680": [153, 451]} | - Anaphase-promoting complex subunit 10
- Anaphase promoting complex protein
- Anaphase-promoting complex subunit 4
- Anaphase-promoting complex subunit 5
- Anaphase-promoting complex subunit 1
- Mitotic spindle checkpoint protein MAD2
- Anaphase-promoting complex subunit 7
- B-type cell cycle switch protein ccs52B
- A... | - IPR056150: CDC20/Fizzy, WD40 domain (domain) [160-449]
- IPR033010: WD repeat Cdc20/Fizzy (family) [38-458]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [157-457]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [146-455]
- IPR001680: WD40 re... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of bio... |
Q6PB30 | Chondrosarcoma-associated gene 1 protein | May play an important role in maintaining centrosome integrity during mitosis | Homo sapiens (Human) | 78 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes at spindle poles and/or centrosomes in both mitotic and interphase cells. Spindle pole localization is more pronounced during mitosis. Centrosomal localization culminates at prophase | MSATTACWPAFTVLGEARGDQVDWSRLYRDTGLVKMSRKPRASSPFSNNHPSTPKRFPRQPRREKGPVKEVPGTKGSP | [
"GO:0000226",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007098",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022402",
"GO:0031023",
"GO:0071840",
"GO:0000922",
"GO:0005575",
"GO:0005622",
"GO:0005813",
"GO:0005815",
"GO:0005819",
"GO:0005856",
"GO:0015630"... | [
"GO:0000226",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007098",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022402",
"GO:0031023",
"GO:0071840"
] | [] | [
"GO:0000922",
"GO:0005575",
"GO:0005622",
"GO:0005813",
"GO:0005815",
"GO:0005819",
"GO:0005856",
"GO:0015630",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q6PB30-F1-model_v6.pdb | 9606.ENSP00000359310 | [
"Q9HAY2",
"Q32NC6",
null,
"Q8N9Q9",
"Q6FHI6",
"Q9UJ55",
"Q9UNF1",
"Q6NW44",
"Q9H214",
null,
"Q9NSD3",
"P43355"
] | null | NaN | - Melanoma-associated antigen 12
- Melanoma-associated antigen 3
- Melanoma-associated antigen 6
- Melanoma-associated antigen F1
- Melanoma-associated antigen 1
- Neuronal PAS domain-containing protein 4
- Non-structural maintenance of chromosomes element 3 homolog
- Melanoma-associated antigen 2
- Melanoma-associated... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0... | |
Q59PG6 | COP9 signalosome complex subunit 5 | Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 609 | Cytoplasm. Nucleus | MTCLDELAHSLESKSDTTNFKTRNSKIKTIDLYQQNELSGKHPQDQDKFYRLPAIDPIARDKKPWKEDINYFNKCYISSLALMKMCTHAQTGGSIEIMGMLVGKISGHSIIVMDTYRLPVEGTETRVNAQNEAYTYMVEYLTERQQLSNGKNEENIVGWYHSHPGYGCWLSGIDVSTQSLNQGFQDPYLAIVVDPVKTLKQGKVEIGAFRTYPEGSQQQPSMTNKTRKDQNKPHNSGANANRKILPKSKQKDFGSHADKYYSLDIEIFTSSWDDKVIEMLKDEDSLTWMKNLLVDSNNNDKILGIRKDEIRSIELIKNYE... | [
"GO:0000338",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0019538",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043687",
"GO:0044238",
"GO:0070646",
"GO:0070647"
] | [
"GO:0000338",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0019538",
"GO:0036211",
"GO:0043170",
"GO:0043412",
"GO:0043687",
"GO:0044238",
"GO:0070646",
"GO:0070647"
] | [] | [] | AF-Q59PG6-F1-model_v6.pdb | 237561.Q59PG6 | [
"Q5AML1",
"Q5A915",
"A0A1D8PGE3",
"Q5ADW3",
"A0A1D8PDR1",
"Q5A6S2",
"Q5ALI9",
"Q59RI7",
"Q5ADU3",
"Q59S45",
"A0A1D8PNA8",
"A0A1D8PJL5",
"A0A1D8PL68",
"A0A1D8PRP1",
"Q59X29",
"Q5ADS0",
"A0A1D8PGQ5",
"Q59ZV5",
"Q5APS5",
"Q59UH5",
"A0A1D8PPC6",
"A0A1D8PLW8",
"Q5ACM9",
"A0A... | [
"IPR037518",
"IPR000555",
"IPR050242"
] | {"IPR050242": [62, 345], "IPR000555": [72, 214], "IPR037518": [75, 215]} | - JAB1/MPN/MOV34 metalloenzyme domain-containing protein
- F-box protein COS111
- PCI domain-containing protein
- PCI domain-containing protein
- Cullin
- NEDD8 family protein
- E3 ubiquitin ligase complex SCF subunit
- Defective in cullin neddylation protein 1
- Cullin
- SCF ubiquitin ligase complex subunit | - IPR037518: MPN domain (domain) [75-215]
- IPR000555: JAB1/MPN/MOV34 metalloenzyme domain (domain) [72-214]
- IPR050242: JAMM/MPN+ metalloenzymes, peptidase M67A (family) [62-345] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016787 (hydrolase activity), GO:0005515 (protein binding), GO:0008233 (peptidase activity), GO:0004175 (endopeptidase activity), GO:0008237 (metallop... |
A0A8M9PFP2 | Calsyntenin-3 | Synaptic adhesion molecule. Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with presynaptic neurexins (By similarity) | Danio rerio (Zebrafish) (Brachydanio rerio) | 956 | Postsynaptic cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Most prominent in the postsynaptic specializations of asymmetric (type I) synapses | MARMSFLSFLLFCLTSVAHGNKANKHKPWIETEYQGIVMENDNTVLLNPPLFALDKDAPLHYAGEICGFRVHNGPGGSGSAQFEAVVLDRSTGEGLVRSKEPLDCESQKEHSFTIQAYDCGEGPDGTNSKKSHKATVHVRVNDVNEFSPVFVERRYEASVPEGRLFDRIVRVEAVDADCSPQYSQICFYDIITPNVPFTIDNDGNIKNTEPLDSKRQRVHSFWVTAFDCGKNRAQADAQVIVTVKPSCKPGWIGWTKRIEYTPGSGSIPLFPNLHLETCEETVWNIQATVELQTSHIGKGCDRDSYSDRSVRRLCGAVRG... | [
"GO:0007155",
"GO:0007156",
"GO:0008150",
"GO:0009987",
"GO:0098609",
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0050839",
"GO:0098631",
"GO:0098632"
] | [
"GO:0007155",
"GO:0007156",
"GO:0008150",
"GO:0009987",
"GO:0098609"
] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0050839",
"GO:0098631",
"GO:0098632"
] | [] | AF-A0A8M9PFP2-F1-model_v6.pdb | null | null | [
"IPR002126",
"IPR015919",
"IPR013320",
"IPR045588"
] | {"IPR015919": [26, 247], "IPR013320": [321, 555], "IPR002126": [30, 271], "IPR045588": [566, 910]} | - IPR002126: Cadherin-like (domain) [30-271]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [26-247]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [321-555]
- IPR045588: Calsyntenin, C-terminal (domain) [566-910] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0051179 (localization), GO:0042592 (homeostatic process), GO:0032502 (developmental process), GO:0009987 (cellular process), GO:0032501 (multicellular... | |
Q9BQT9 | Calsyntenin-3 | Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation. Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with both neurexin-alpha and neurexin-beta proteins at the presynaptic membran... | Homo sapiens (Human) | 956 | Postsynaptic cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cell projection, dendrite. Note=Most prominent in the postsynaptic specializations of asymmetric (type I) synapses with bot... | MTLLLLPLLLASLLASCSCNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAGEICGFRLHGSGVPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQGWNKRIEYAPGAGSLALFPGIRLETCDEPLWNIQATIELQTSHVAKGCDRDNYSERALRKLCGAATGEVDLLP... | [
"GO:0005975",
"GO:0005996",
"GO:0006082",
"GO:0006996",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0016043",
"GO:0019752",
"GO:0019852",
"GO:0034389",
"GO:0043436",
"GO:0044087",
"GO:0044238",
"GO:0044281",
"GO:0048284",
"GO:0050789",
"GO:0050794",
"GO:0050803",
"GO:0050807"... | [
"GO:0005975",
"GO:0005996",
"GO:0006082",
"GO:0006996",
"GO:0008150",
"GO:0008152",
"GO:0009987",
"GO:0016043",
"GO:0019752",
"GO:0019852",
"GO:0034389",
"GO:0043436",
"GO:0044087",
"GO:0044238",
"GO:0044281",
"GO:0048284",
"GO:0050789",
"GO:0050794",
"GO:0050803",
"GO:0050807"... | [] | [] | AF-Q9BQT9-F1-model_v6.pdb | 9606.ENSP00000266546 | [
"Q9Y2D6",
"Q9ULB1"
] | [
"IPR002126",
"IPR015919",
"IPR013320",
"IPR045588"
] | {"IPR015919": [25, 243], "IPR013320": [315, 549], "IPR002126": [29, 246], "IPR045588": [559, 912]} | - Neurexin-1
- Neurexin-2 | - IPR002126: Cadherin-like (domain) [29-246]
- IPR015919: Cadherin-like superfamily (homologous_superfamily) [25-243]
- IPR013320: Concanavalin A-like lectin/glucanase domain superfamily (homologous_superfamily) [315-549]
- IPR045588: Calsyntenin, C-terminal (domain) [559-912] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0048583 (re... |
Q9H6J7 | Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | Regulator of the tubulin polyglutamylase complex (TPGC) that controls cytoskeletal organization, nuclear shape, and cilium disassembly by balancing microtubule and actin assembly. Regulates the assembly and stability of the TPGC and thereby modulates polyglutamylation of the microtubule, which antagonizes MAP4 binding | Homo sapiens (Human) | 331 | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton. Note=Associated with microtubules | MLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENREDISQYGIARFFTEYFNSVCQGTHILFREFSFVQATPHNRVSFLRAFWRCFRTVGKNGDLLTMKEYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLDSVAAIYEDLLSGKNPNTVIVPTSSSGQHRQRPALGGAGTLEGVEASLFYQCLENLCDRHKYSCPPPALVKEALSNVQRLTFYGFLMALSKHRGINQALGALPDKGDLMHDPAMDEELERLLAQVPGLVNSVTASPEASCLPSRTPPRVGSPWRPLHHSRKVDGESD... | [
"GO:0000226",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022411",
"GO:0022607",
"GO:0030030",
"GO:0031109",
"GO:0043933",
"GO:0044085",
"GO:0044782",
"GO:0046785",
"GO:0051258",
"GO:0061523",
"GO:0061635",
"GO:0065003",
"GO:0065007"... | [
"GO:0000226",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022411",
"GO:0022607",
"GO:0030030",
"GO:0031109",
"GO:0043933",
"GO:0044085",
"GO:0044782",
"GO:0046785",
"GO:0051258",
"GO:0061523",
"GO:0061635",
"GO:0065003",
"GO:0065007"... | [] | [] | AF-Q9H6J7-F1-model_v6.pdb | 9606.ENSP00000367878 | [
"Q8N978",
"Q9Y435",
"Q9UMU0",
"Q96GE2",
"Q9NXM6",
"Q9BSH3"
] | [
"IPR038968"
] | {"IPR038968": [1, 331]} | - Leucine-rich repeat-containing protein 49
- Polyglutamylase complex subunit TTLL1
- Tubulin polyglutamylase complex subunit 2
- Nicolin-1
- Tubulin polyglutamylase complex subunit 1
- Eukaryotic translation initiation factor 3 subunit F | - IPR038968: Centriolar satellite-associated tubulin polyglutamylase complex regulator 1 (family) [1-331] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellula... |
Q94480 | Cytoplasmic tRNA 2-thiolation protein 1 | Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thioca... | Dictyostelium discoideum (Social amoeba) | 360 | Cytoplasm | MENTATKKKSKLCEVCNVSRPVLKRPKTGEMICKECFYTVFEDEIHHTIISNNLFKRGDRVAIGASGGKDSTVLAEIMTLLNKKYDYGLDLFLLSIDEGITGYRDDSLETVKRNQEQYQIPLKILSYKELYNWTMDDIVKEIGLKGNCTFCGVFRRQALDRGAVMLKANKIVTGHNADDIAETVLMNLLRGDIPRLQRCVNIITGSEGALPRSKPFKYTYQKEIVMYAYFKKLDYFSTECIYAPNAYRGHARDFLKDLEAVRPSIIIDIIHSAENFHFREENKMPVQRNCIQCGYICSNDICMACDLLKNLNSGLAKVKL... | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016782",
"GO:0016783",
"GO:0103016",
"GO:0140098",
"GO:0140101",
"GO:0140640",
"GO:0002144",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0032991",
"GO:0110165",
"GO:0140535",
"GO:1902494",
"GO:1990228",
"GO:1990234"... | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016782",
"GO:0016783",
"GO:0103016",
"GO:0140098",
"GO:0140101",
"GO:0140640"
] | [
"GO:0002144",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0032991",
"GO:0110165",
"GO:0140535",
"GO:1902494",
"GO:1990228",
"GO:1990234"
] | AF-Q94480-F1-model_v6.pdb | 44689.Q94480 | [
"Q54NM6",
"Q54NM8",
"Q1ZXC6",
"Q54P40",
"Q54CP4",
"Q55FS0",
"Q55EX7",
"Q54VS1",
"Q86HF4"
] | [
"IPR056369",
"IPR011063",
"IPR014729",
"IPR020554",
"IPR000541",
"IPR032442",
"IPR035107"
] | {"IPR014729": [12, 334], "IPR000541": [11, 323], "IPR035107": [12, 318], "IPR056369": [41, 246], "IPR011063": [61, 239], "IPR032442": [288, 318], "IPR020554": [33, 70]} | - Cytoplasmic tRNA 2-thiolation protein 2
- Elongator complex protein 3
- Adenylyltransferase and sulfurtransferase MOCS3
- DNA replication licensing factor mcm5
- Molybdopterin synthase catalytic subunit
- Molybdenum cofactor biosynthesis protein 1
- Molybdopterin synthase sulfur carrier subunit
- Iron-sulfur cluster ... | - IPR056369: Cytoplasmic tRNA 2-thiolation protein 1-like, ATP-binding domain (domain) [41-246]
- IPR011063: tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal (domain) [61-239]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [12-334]
- IPR020554: Uncharacterised protein family UP... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016740 (transferase activity), GO:0140098 (catalytic activity, acting on RNA), GO:0016782 (transferase activity, transferring sulphur-containing groups), GO:0016783 (... |
Q55EX7 | Cytoplasmic tRNA 2-thiolation protein 2 | Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with ctu1/atpbd3 that ligates sulfur from thiocarboxylated urm1 onto the uridine of tRNAs at wobble position | Dictyostelium discoideum (Social amoeba) | 523 | Cytoplasm | MSSEELPSCGINDNDINNTIPINTRKVQIIPNGNTQCVKCLYNVANNVKDKKLSKKEKKEQKLKEEENNNNNNEEPITQQQKPIGKPIINFRSEQLCWECYRELILKKFKLNIVKVRESKRDAEKLLVALSGGTCSSMLLELLKQCTEGSGKAKMFLDIKCVHIDESSITPYQNHNDTIEFLKEFNNVKLGFPNLEIIPLEDILGTVTPLGERTNQLKLQFAQLSSETSKEDLLLYYRNQLLIQVAHKLNCKKVILGTSSNRLAVQLVASTSKGRGFSVPNETSVIIEQPSNDIKFYQPMRDFLLKEIFIYYRHLNILPV... | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016782",
"GO:0016783",
"GO:0103016",
"GO:0140098",
"GO:0140101",
"GO:0140640"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016740",
"GO:0016782",
"GO:0016783",
"GO:0103016",
"GO:0140098",
"GO:0140101",
"GO:0140640"
] | [] | AF-Q55EX7-F1-model_v6.pdb | 44689.Q55EX7 | [
"Q55FS0",
"Q54X02",
"Q54RL9",
"Q54BN1",
"Q54GN1",
"Q54NX0",
"Q1ZXC6",
"Q54CP4",
"Q55GM1"
] | [
"IPR019407",
"IPR014729"
] | {"IPR014729": [79, 422], "IPR019407": [23, 508]} | - Cytoplasmic tRNA 2-thiolation protein 1
- Elongator complex protein 3
- DNA replication licensing factor mcm5
- Cysteine desulfurase
- tRNA(Ile)-lysidine synthetase
- Adenylyltransferase and sulfurtransferase MOCS3
- Peptidase M20 dimerisation domain-containing protein
- Acetylornithine deacetylase
- pre-rRNA 2'-O-ri... | - IPR019407: Cytoplasmic tRNA 2-thiolation protein 2 (family) [23-508]
- IPR014729: Rossmann-like alpha/beta/alpha sandwich fold (homologous_superfamily) [79-422] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... |
P53137 | RQC trigger complex subunit CUE3 | Involved in activation of the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation. Specifically recognizes and binds RPS20/uS10 ubiquitinated by HEL2, promoting recruitment of the RQT (ribosome quality control trigger) complex on stalled ribosomes, follo... | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | 624 | Cytoplasm | MLSRYNRVIEINGGNADISLPIVKFPPFKLRAQLIEKDPVVWLHLIETYVTYFEYLMQGANVELLDESTLDHLRLFLRTYLHEIADEEGKLLSLGINHDVSEQLYLLKGWIFSLIKKCGLLHLQIFGDSLWNLIKVYVRRNPDSIRGLIDGSLKPRINTQRVQLDKSYQVQQHLKQLIESGKFKRIDLRCVEDLLSAKSMQPNKFAENFFTANWIEILEALWAKGQGRGHKEARELIIISLFSVSADRLLKITKELGISNFETLALYPLLGTMLINEGVHKRLPDLKSKLLFLNLGGLSMDEGDHMSYPTSSGTEVNEEQ... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0031593",
"GO:0032182",
"GO:0043130",
"GO:0070530",
"GO:0140030",
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0005840",
"GO:0022626",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0031593",
"GO:0032182",
"GO:0043130",
"GO:0070530",
"GO:0140030"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0005840",
"GO:0022626",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-P53137-F1-model_v6.pdb | 4932.YGL110C | [
"Q06336",
"P32639",
"Q12532",
"Q08745",
"P46784",
"Q05580",
"P36075",
"P53327",
"P36119",
"P51979",
"P38701"
] | [
"IPR052586",
"IPR041808",
"IPR003892"
] | {"IPR052586": [314, 615], "IPR003892": [316, 359], "IPR041808": [318, 358]} | - RQC trigger complex helicase SLH1
- RQC trigger complex subunit RQT4
- Ribosome quality control complex subunit 2
- E3 ubiquitin-protein ligase HEL2
- ADP-ribosylation factor-binding protein GGA1
- Small ribosomal subunit protein uS10
- ATP-dependent DNA helicase MER3
- Small ribosomal subunit protein eS10A
- Small r... | - IPR052586: Activating signal cointegrator 1 complex subunit 2 (family) [314-615]
- IPR041808: CUE domain-containing protein 3, CUE domain (domain) [318-358]
- IPR003892: Ubiquitin system component CUE (domain) [316-359] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0003676 (nucleic acid binding), GO:0003677 (DNA binding), GO:0001067 (transcription regulatory region nucleic acid bi... |
A0A3Q7HJG4 | Cuscuta receptor 1 | Involved in plant defense. Contributes to resistance against parasitic plant C.reflexa. Acts as a receptor for the 11 kDa glycine-rich protein (GRP) of C.reflexa inducing immune responses such as emission of stress-related phytohormone ethylene, reactive oxygen species (ROS) release, and hypersensitive cell death. Reco... | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) | 1,121 | Cell membrane; Single-pass membrane protein. Cell surface | MGNIKFLLLVFFLIVVVVNGCWEEERNALLELQTNIMSSNGELLVDWAGYNAAHFVDCCFWDRVKCSLETGRVIKLDLEADFGTGDGWLFNASLFLPFKSLQVLLLSSQNIIGWTKNEGFSKLRQLPNLKEVDLQYNPIDPKVLLSSLCWISSLEVLKLGVDVDTSFSIPMTYNTNMMSKKCGGLSNLRELWFEGYEINDINILSALGELRNLEKLILDDNNFNSTIFSSLKIFPSLKHLNLAANEINGNVEMNDIIDLSNLEYLDLSDNNIHSFATTKGNKKMTSLRSLLLGSSYSNSSRVIRSLKSFSSLKSLSYKNS... | [
"GO:0002218",
"GO:0002220",
"GO:0002221",
"GO:0002241",
"GO:0002242",
"GO:0002253",
"GO:0002376",
"GO:0002429",
"GO:0002682",
"GO:0002684",
"GO:0002752",
"GO:0002757",
"GO:0002758",
"GO:0002764",
"GO:0002768",
"GO:0002831",
"GO:0002833",
"GO:0006950",
"GO:0006952",
"GO:0006955"... | [
"GO:0002218",
"GO:0002220",
"GO:0002221",
"GO:0002241",
"GO:0002242",
"GO:0002253",
"GO:0002376",
"GO:0002429",
"GO:0002682",
"GO:0002684",
"GO:0002752",
"GO:0002757",
"GO:0002758",
"GO:0002764",
"GO:0002768",
"GO:0002831",
"GO:0002833",
"GO:0006950",
"GO:0006952",
"GO:0006955"... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0038023",
"GO:0038187",
"GO:0060089"
] | [
"GO:0005575",
"GO:0005886",
"GO:0016020",
"GO:0071944",
"GO:0110165"
] | AF-A0A3Q7HJG4-F1-model_v6.pdb | 4081.A0A3Q7HJG4 | null | [
"IPR003591",
"IPR051502",
"IPR032675",
"IPR001611"
] | {"IPR032675": [18, 1040], "IPR051502": [379, 1094], "IPR003591": [126, 986], "IPR001611": [211, 983]} | - IPR003591: Leucine-rich repeat, typical subtype (repeat) [126-986]
- IPR051502: Receptor-like Defense Trigger (family) [379-1094]
- IPR032675: Leucine-rich repeat domain superfamily (homologous_superfamily) [18-1040]
- IPR001611: Leucine-rich repeat (repeat) [211-983] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0009605 (response to extern... | |
A0A1D8PFP9 | DASH complex subunit DAD1 | Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosom... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 99 | Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Nucleus | MSNSSSNPSKNEYFIKQRDLLIQEISNNLSIVQTNLETLNRSLHESKQIGKEFDDVARLWSTFYDGMNGMNHQTRENTRDENNKISSSDTEDENNNNKI | [
"GO:0008150",
"GO:0030447",
"GO:0040007"
] | [
"GO:0008150",
"GO:0030447",
"GO:0040007"
] | [] | [] | AF-A0A1D8PFP9-F1-model_v6.pdb | 237561.A0A1D8PFP9 | [
"Q59ZG8",
"Q59LN9",
"A0A1D8PM85",
"Q59VC6",
"Q5A1Q5",
"Q59QH6",
"A0A1D8PTL5",
"Q5AMH1",
"Q5APC8"
] | [
"IPR013958"
] | {"IPR013958": [3, 91]} | - DASH complex subunit DAM1
- DASH complex subunit DAD2
- DASH complex subunit SPC19
- DASH complex subunit SPC34
- DASH complex subunit DAD3
- DASH complex subunit DAD4
- Probable kinetochore protein NUF2
- DASH complex subunit ASK1
- Histone H3-like centromeric protein CSE4 | - IPR013958: DASH complex subunit Dad1 (family) [3-91] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding), GO:0051010 (microtubule plus-end binding)
Biological Process (BP): GO:0008150 (biological process), GO:... |
Q59ZG8 | DASH complex subunit DAD2 | Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosom... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 125 | Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore. On the spindle, localizes to the midzone | MSKTNTAIYQKIAEKRANLERFREFKELTDDLVLQLESIGDKLETMNGGTASVALILANWKSVVQSISLASLALMKESNDNNKEAFPEPLVRVRVGQSNEENQDEEEADEEEGVRDSEEVEESTE | [
"GO:0000086",
"GO:0000278",
"GO:0007049",
"GO:0007059",
"GO:0008150",
"GO:0008608",
"GO:0009987",
"GO:0022402",
"GO:0030447",
"GO:0040007",
"GO:0044770",
"GO:0044772",
"GO:0044839",
"GO:0050000",
"GO:0051179",
"GO:0051310",
"GO:0051640",
"GO:0098813",
"GO:1903047",
"GO:0003674"... | [
"GO:0000086",
"GO:0000278",
"GO:0007049",
"GO:0007059",
"GO:0008150",
"GO:0008608",
"GO:0009987",
"GO:0022402",
"GO:0030447",
"GO:0040007",
"GO:0044770",
"GO:0044772",
"GO:0044839",
"GO:0050000",
"GO:0051179",
"GO:0051310",
"GO:0051640",
"GO:0098813",
"GO:1903047"
] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0008017",
"GO:0008092",
"GO:0015631"
] | [] | AF-Q59ZG8-F1-model_v6.pdb | 237561.Q59ZG8 | [
"Q5A1Q5",
"Q59VC6",
"A0A1D8PTL5",
"Q59QH6",
"Q5AMH1",
"Q5APC8",
"Q5A6Q0",
"Q59P88",
"A0A1D8PFP9",
"Q59LN9",
"A0A1D8PM85",
"A0A1D8PS42"
] | [
"IPR013963"
] | {"IPR013963": [1, 103]} | - DASH complex subunit DAD3
- DASH complex subunit SPC19
- DASH complex subunit SPC34
- DASH complex subunit DAD1
- DASH complex subunit DAD4
- DASH complex subunit DAM1
- DASH complex subunit ASK1
- Probable kinetochore protein NUF2
- Spindle pole body component
- Histone H3-like centromeric protein CSE4 | - IPR013963: DASH complex subunit Dad2 (family) [1-103] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding), GO:0051010 (microtubule plus-end binding)
Biological Process (BP): GO:0008150 (biological process), GO:... |
Q59VC6 | DASH complex subunit DAD3 | Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosom... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 138 | Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore | MSFTTKDKSDDSSIITTNYADNPNLSPIEQKILQQYQLMNNNLIKVSNELELLTNTTDEFGKGKGSSIHLVENLRQLETKLVFVYTFFKGAVYSILNAQDYIAEQETNGLEETNEEEDGNEEDESGNVELSGVSADEN | [
"GO:0008150",
"GO:0030447",
"GO:0040007"
] | [
"GO:0008150",
"GO:0030447",
"GO:0040007"
] | [] | [] | AF-Q59VC6-F1-model_v6.pdb | 237561.Q59VC6 | [
"A0A1D8PM85",
"A0A1D8PS42",
"Q59P88",
"A0A1D8PFP9",
"Q59ZG8",
"Q5A6Q0",
"Q5A693",
"Q5APC8",
"Q5AMH1",
"A0A1D8PTL5",
"Q59QH6"
] | [
"IPR013965"
] | {"IPR013965": [11, 117]} | - DASH complex subunit SPC34
- DASH complex subunit DAD2
- DASH complex subunit SPC19
- DASH complex subunit DAD4
- DASH complex subunit DAM1
- DASH complex subunit ASK1
- DASH complex subunit DUO1
- DASH complex subunit DAD1
- Actin-related protein 5
- Spindle pole body component | - IPR013965: DASH complex subunit Dad3 (family) [11-117] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding), GO:0051010 (microtubule plus-end binding)
Biological Process (BP): GO:0008150 (biological process), GO:... |
Q5APC8 | DASH complex subunit DAM1 | Component of the DASH complex that connects microtubules with kinetochores and couples microtubule depolymerisation to chromosome movement; it is involved in retrieving kinetochores to the spindle poles before their re-orientation on the spindle in early mitosis and allows microtubule depolymerization to pull chromosom... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 277 | Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Localization to the kinetochore is independent of microtubules | MSSSKPVTPRNDRRQNSGRRHSHRSSGIQLPSMSPKVHHYPIDAENLPMDSPEIVEKFASLAESMETLDLHMHDLCHIHDHISNQFNESFASFLYGLSMTMWCVDFPGCPSREQWEALISKRERKERIEVLKKRLADAQKLNDRLKLRLSDEAKQKPQQLTSQQRPTHGPTRQIKQQPRSVNFNTHSSDSISTNSYTSGDFNTNRRVSRIPQPSRSNLPSSRFQAPSKSGPNLNQPPRYMRGLFDGNNTLNTSNYSRIKKPIHNRSVNNLQNRPPFR | [
"GO:0008150",
"GO:0030447",
"GO:0040007"
] | [
"GO:0008150",
"GO:0030447",
"GO:0040007"
] | [] | [] | AF-Q5APC8-F1-model_v6.pdb | 237561.Q5APC8 | [
"Q5A693",
"Q59S66",
"Q59ZG8",
"A0A1D8PFP9",
"Q59P88",
"A0A1D8PM85",
"A0A1D8PS42",
"Q5A216",
"Q59VC6",
"Q59QH6",
"A0A1D8PTL5",
"Q5AMH1"
] | [
"IPR013962"
] | {"IPR013962": [3, 277]} | - DASH complex subunit DAD1
- DASH complex subunit DAD2
- DASH complex subunit SPC34
- DASH complex subunit DAD3
- DASH complex subunit SPC19
- Spindle pole body component
- DASH complex subunit ASK1
- DASH complex subunit DUO1
- DASH complex subunit DAD4
- Mitochondrial 54S ribosomal protein YmL11 | - IPR013962: DASH complex subunit Dam1 (family) [3-277] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0008092 (cytoskeletal protein binding), GO:0015631 (tubulin binding), GO:0008017 (microtubule binding), GO:0051010 (microtubule plus-end binding)
Biological Process (BP): GO:0008150 (biological process), GO:... |
Q23262 | Protein dao-4 | Probably acts downstream of the Wnt signaling pathway | Caenorhabditis elegans | 217 | Nucleus. Secreted | MKIALYSILLITVCYLSSTDAYLFDPKAVDALLREIRARLQATGKEPHARKIEQETEEIKKEELMQAEDVEGSGSGEEIEGSGEVISTITGVPIMDNEEKKDLKPENFPRPEPIFDKYGNLKSKDKLEALTYSNFKKQAPATLQDHYNLNPTGTLQMLQGLDIHGGSGGYHRALSGGYLPPSTYDPYNVNWHSYGDEGVKMKDKAISVFRRVIAPGR | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [
"GO:0007275",
"GO:0008150",
"GO:0032501",
"GO:0032502",
"GO:0040002",
"GO:0042335",
"GO:0048856"
] | [] | [] | AF-Q23262-F1-model_v6.pdb | 6239.ZC373.6.1 | [
"Q23338",
"Q23447",
"Q9N4U2",
"O44989",
"Q20754",
"A3QM98"
] | null | NaN | - Cuticle collagen 49
- Cuticle collagen 71
- Nematode cuticle collagen N-terminal domain-containing protein
- Cuticle collagen 38
- peptidylprolyl isomerase
- Prion-like-(Q/N-rich)-domain-bearing protein | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of... | |
Q9D757 | Death-associated protein-like 1 | May play a role in the early stages of epithelial differentiation or in apoptosis | Mus musculus (Mouse) | 107 | null | MANEVQVLPSPLKGRYAPAVKAGGMRISKKQEMGVLERHTKKTGLEKTSAITNVAKIQMLDALTDTLDKLNHKFPATVHTAHQKPTPALEKAAPMKRAYIIQQPRKC | [
"GO:0002682",
"GO:0002683",
"GO:0002694",
"GO:0002695",
"GO:0007162",
"GO:0008150",
"GO:0008152",
"GO:0008283",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0022407",
"GO:0022408",
"GO:0030155",
"GO:0043170",
"GO:0046634",
"GO:0046636",
"GO:0048519",
"GO:0048523"... | [
"GO:0002682",
"GO:0002683",
"GO:0002694",
"GO:0002695",
"GO:0007162",
"GO:0008150",
"GO:0008152",
"GO:0008283",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0022407",
"GO:0022408",
"GO:0030155",
"GO:0043170",
"GO:0046634",
"GO:0046636",
"GO:0048519",
"GO:0048523"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-Q9D757-F1-model_v6.pdb | 10090.ENSMUSP00000028369 | [
"P47933",
"P62301",
"Q9CQR2",
"Q9D8E6",
"P97351",
"Q3V288",
"Q9CXW4",
"Q9CZM2",
"P97461",
"Q544E4",
"Q02877",
"Q9D1R9",
"P62852",
"Q9CY13",
"P61358",
"Q8C2G6",
"P84099",
"P62889",
"Q9JJ24",
"Q9ERM6",
"Q9DCQ4",
"P63276",
"Q9JKS5",
"P61514",
"Q8BP67",
"P25444",
"P62... | [
"IPR024130"
] | {"IPR024130": [1, 106]} | - Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein
- Large ribosomal subunit protein eL14
- Small ribosomal subunit protein uS19
- Small ribosomal subunit protein eS1
- Small ribosomal subunit protein uS7
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein uL24
- Small ribosomal subunit pr... | - IPR024130: DAP1/DAPL1 (family) [1-106] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biol... |
P0A8X0 | Dual-action ribosomal maturation protein DarP | Member of a network of 50S ribosomal subunit biogenesis factors (ObgE, RluD, RsfS and DarP) which assembles along the 30S-50S interface, preventing incorrect 23S rRNA structures from forming. Promotes peptidyl transferase center (PTC) maturation. Binds pre-50S ribosomal subunits near the 23S rRNA L1 stalk, where it may... | Escherichia coli (strain K12) | 183 | Cytoplasm. Note=Associates with late stage pre-50S ribosomal subunits | MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG | [
"GO:0003674",
"GO:0005488",
"GO:0043021",
"GO:0043022",
"GO:0043023",
"GO:0044877"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0043021",
"GO:0043022",
"GO:0043023",
"GO:0044877"
] | [] | AF-P0A8X0-F1-model_v6.pdb | 511145.b4234 | [
"Q2M6V9",
"Q2M7V0",
"Q2M6W7",
"Q2MAQ6",
"Q2M815",
"Q2M6A2",
"Q2M6X5",
"Q2M932",
"Q2M6X4",
"Q2M6W6",
"Q2M6Y5",
"Q2M6X8",
"Q2M7V1",
"Q2M929",
"Q2M6W9",
"Q2M6Y0",
"Q2M6Y4",
"Q2M6Y3",
"Q2M926",
"Q2M6Y2",
"Q2M6X0",
"Q2M8Y2",
"Q2M6X3",
"Q2M8N2",
"Q2M8R9",
"Q2M8S1",
"Q2M... | [
"IPR006839",
"IPR023153"
] | {"IPR023153": [37, 183], "IPR006839": [1, 182]} | - Ribosomal large subunit pseudouridine synthase D
- Ribosomal silencing factor RsfS
- Ribosomal silencing factor RsfS
- Ribosomal silencing factor RsfS
- GTPase ObgE/CgtA
- Large ribosomal subunit protein bL33
- RNA-binding protein YhbY
- Large ribosomal subunit protein uL24
- Large ribosomal subunit protein bL32
- La... | - IPR006839: Dual-action ribosomal maturation protein DarP (family) [1-182]
- IPR023153: Dual-action ribosomal maturation protein DarP superfamily (homologous_superfamily) [37-183] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0003729 (mRNA binding)
Biological Process (BP): GO:0008150 (biological process), GO:00... |
I1MRZ6 | Diacylglycerol O-acyltransferase 3-2 | Involved in triacylglycerol (TAG) biosynthesis. Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA. Incorporates preferentially monounsaturated fatty acids (MUFAs), especially oleic acid (C18:1) and to some extent palmitoleic acid (C16:1), into TAGs accumulating in seeds oil. Can ... | Glycine max (Soybean) (Glycine hispida) | 338 | Cytoplasm | MEISGTVLRQVSYVSGYGTHTRSRGLAPRFGVRMGMGSGFCDEGHLRYYQDTKKVLTPKKKLKLLKGFSKLGLASDPEKLAMFYDLQQNLTSDAGDVLLRELEAARAKEKEVKKKRKQEKKAKLKAAKMNCESSSSSSSESSDSDCGCDQVVDMNTFRAGVGVGVGVGVGVVAPAPVEESPLPKTAPIVEDANAHCVAMELCSKNDIYVSSASNGFKNESAVVTSAPQKRIEVCMGNKCKRSGAAALMQEFEKVVGVEGVAVVACKCMGKCKTAPNVKVQNSVDHNSLAQGLDDSVKIPANPLCIGVGLEDVDAIVARYF... | [
"GO:0006629",
"GO:0006638",
"GO:0006639",
"GO:0006641",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0019432",
"GO:0044238",
"GO:0045017",
"GO:0046460",
"GO:0046463",
"GO:0046486",
"GO:0003674",
"GO:0003824",
"GO:0004144",
"GO:0008374",
"GO:0016411"... | [
"GO:0006629",
"GO:0006638",
"GO:0006639",
"GO:0006641",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0019432",
"GO:0044238",
"GO:0045017",
"GO:0046460",
"GO:0046463",
"GO:0046486"
] | [
"GO:0003674",
"GO:0003824",
"GO:0004144",
"GO:0008374",
"GO:0016411",
"GO:0016740",
"GO:0016746",
"GO:0016747"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0110165"
] | AF-I1MRZ6-F1-model_v6.pdb | 3847.I1MRZ6 | [
"Q1MW30",
"A0A0R0G008",
"K7LZ65",
"A0A0R0G279",
"Q5GKZ7",
"K7K424",
"I1L4N0",
"I1MMV5"
] | [
"IPR036249"
] | {"IPR036249": [226, 285]} | - Diacylglycerol O-acyltransferase 1B
- Acyltransferase
- Diacylglycerol O-acyltransferase 2D
- Acyltransferase
- Acyltransferase
- Diacylglycerol O-acyltransferase 3-1
- diacylglycerol O-acyltransferase
- Diacylglycerol O-acyltransferase 1A | - IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [226-285] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0043167 (ion binding), GO:0016740 (transferase activity), GO:0043169 (cation binding), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acy... |
Q59KM8 | Cell cycle protein kinase DBF2 | Ser/Thr-protein kinase involved in the mitotic exit network (MEN) and required after the metaphase to anaphase cell cycle transition. Required for proper nuclear segregation, mitotic spindle organization, actomyosin ring contraction, primary septum assembly, and normal hyphal morphogenesis | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 710 | Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Cytoplasm, cytoskeleton, spindle. Nucleus. Bud neck. Note=In small unbudded G1 cells, localizes to the spindle pole body (SPB). At the G1/S transition, remains associated with the SPB but also starts to accumulate in a linear structure in the nu... | MTNFFNRSPKHQSHHYQPHQQDVTDISYSMENVSISSNAMMDIDTSYRSSKPTYNNPQQQQQQQQQQQAQNNLFNKENITPLNSPTKSILHNSPQQAKSSTSPQHLYNKLVNANYNGNSPQPGIQQQQNNRALQNNINQLQPPLNKRYKLTEAEFYAKANSARTKRLTSIAQLYFLDYYCDMFDYVINRRERTAIVEKNLLTDPMYKNDITKQQFEWKNYIGRERALLRKRRLKPKHKDFEMITQIGQGGYGQVFLSRKRDTREICALKILNKKLLIKLDETRHVLTERDILTNTRSDWLVKLLYAFQDQEKVFLAMEFV... | [
"GO:0000226",
"GO:0000278",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007051",
"GO:0007052",
"GO:0007096",
"GO:0007346",
"GO:0008150",
"GO:0009987",
"GO:0010564",
"GO:0016043",
"GO:0022402",
"GO:0030447",
"GO:0030448",
"GO:0040007",
"GO:0050789",
"GO:0050794"... | [
"GO:0000226",
"GO:0000278",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007051",
"GO:0007052",
"GO:0007096",
"GO:0007346",
"GO:0008150",
"GO:0009987",
"GO:0010564",
"GO:0016043",
"GO:0022402",
"GO:0030447",
"GO:0030448",
"GO:0040007",
"GO:0050789",
"GO:0050794"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005815",
"GO:0005816",
"GO:0005856",
"GO:0015630",
"GO:0030428",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0110165"
] | AF-Q59KM8-F1-model_v6.pdb | 237561.Q59KM8 | [
"A0A1D8PGP6",
"Q59UQ6",
"Q5ALY0",
"Q5ABG0",
"Q5ALV8",
"A0A1D8PH81",
"Q5AH02",
"Q5AC22",
"Q5ADQ2",
"A0A1D8PHR4",
"A0A1D8PHB0",
"A0A1D8PCX9",
"Q59NH8",
"Q5ABC6",
"A0A1D8PJL3",
"Q5A3L7"
] | [
"IPR008271",
"IPR050236",
"IPR011009",
"IPR017441",
"IPR000961",
"IPR000719"
] | {"IPR011009": [219, 578], "IPR050236": [68, 599], "IPR000719": [240, 557], "IPR000961": [558, 658], "IPR008271": [359, 371], "IPR017441": [246, 269]} | - Mob1p
- Tyrosine-protein phosphatase CDC14
- Serine/threonine protein kinase
- Ras family GTPase
- Serine/threonine-protein kinase
- Serine/threonine protein kinase
- Ras GTPase-activating-like protein IQG1
- Protein phosphatase PP2A regulatory subunit B
- Uncharacterized protein
- G2/mitotic-specific cyclin CLB2 | - IPR008271: Serine/threonine-protein kinase, active site (active_site) [359-371]
- IPR050236: Serine/threonine-protein kinases, AGC (family) [68-599]
- IPR011009: Protein kinase-like domain superfamily (homologous_superfamily) [219-578]
- IPR017441: Protein kinase, ATP binding site (binding_site) [246-269]
- IPR000961... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0140096 (catalytic activity, acting on a protein), GO:0004672 (protein kinase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotrans... |
Q9NV06 | DDB1- and CUL4-associated factor 13 | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, m... | Homo sapiens (Human) | 445 | Nucleus, nucleolus. Note=In the nucleolus, localizes predominantly in the granular component, but also detected in the fibrillar center and dense fibrillar component | MKVKMLSRNPDNYVRETKLDLQRVPRNYDPALHPFEVPREYIRALNATKLERVFAKPFLASLDGHRDGVNCLAKHPEKLATVLSGACDGEVRIWNLTQRNCIRTIQAHEGFVRGICTRFCGTSFFTVGDDKTVKQWKMDGPGYGDEEEPLHTILGKTVYTGIDHHWKEAVFATCGQQVDIWDEQRTNPICSMTWGFDSISSVKFNPIETFLLGSCASDRNIVLYDMRQATPLKKVILDMRTNTICWNPMEAFIFTAANEDYNLYTFDMRALDTPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVY... | [
"GO:0000212",
"GO:0000226",
"GO:0000280",
"GO:0001890",
"GO:0001893",
"GO:0003006",
"GO:0006338",
"GO:0006508",
"GO:0006511",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007051",
"GO:0007056",
"GO:0007059",
"GO:0007143",
"GO:0007276",
"GO:0007292",
"GO:0007565"... | [
"GO:0000212",
"GO:0000226",
"GO:0000280",
"GO:0001890",
"GO:0001893",
"GO:0003006",
"GO:0006338",
"GO:0006508",
"GO:0006511",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007051",
"GO:0007056",
"GO:0007059",
"GO:0007143",
"GO:0007276",
"GO:0007292",
"GO:0007565"... | [] | [] | AF-Q9NV06-F1-model_v6.pdb | 9606.ENSP00000297579 | [
"Q96A77",
"Q9BQ67",
"Q9NWT1",
"P55769",
"Q5BJI0",
"Q9NUY4",
"Q9NYI8",
"Q9NXT6",
"Q9Y2P8",
"Q9Y3H5",
"Q9BVE8",
"Q9BV24",
"Q9DAE4",
"Q9NVJ8",
"Q9BVZ0",
"Q9UK86",
"Q9Y3A8",
"Q96JK2",
"Q96DH1",
"Q8IZ30",
"Q6IB08",
"Q9NQZ2",
"Q8TB19",
"Q9H4P1",
"Q86XJ9",
"Q9Y4P5",
"Q86... | [
"IPR051733",
"IPR036322",
"IPR015943",
"IPR001680",
"IPR019775",
"IPR007287"
] | {"IPR036322": [12, 353], "IPR015943": [40, 391], "IPR051733": [1, 444], "IPR007287": [354, 440], "IPR019775": [82, 96], "IPR001680": [55, 362]} | - U3 small nucleolar RNA-interacting protein 2
- WD repeat-containing protein 36
- Transducin beta-like protein 3
- WD repeat-containing protein 43
- WD repeat-containing protein 3
- U3 small nucleolar RNA-associated protein 4 homolog
- Nucleolar complex protein 4 homolog
- Bystin
- KRR1 small subunit processome compon... | - IPR051733: WD repeat-containing DCAF13/WDSOF1 (family) [1-444]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [12-353]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [40-391]
- IPR001680: WD40 repeat (repeat) [55-362]
- IPR019775: WD40 repeat... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0097159 (organic cyclic compound binding), GO:1901363 (heterocyclic compound binding), GO:0005515 (protein binding), GO:0008134 (transcription factor binding), GO:0003676 (nucleic acid binding), GO:0003723 (RNA binding), GO:0140297 (DNA-... |
Q6PAC3 | DDB1- and CUL4-associated factor 13 | Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre- rRNA and work in concert to generate RNA folding, m... | Mus musculus (Mouse) | 445 | Nucleus, nucleolus. Note=In the nucleolus, localizes predominantly in the granular component, but also detected in the fibrillar center and dense fibrillar component | MKVKMLSRNPDNYVRETKLDIQRVPRNYDPTLHPFEVPREYVRALNATKLERVFAKPFLASLDGHRDGVNCLAKHPKSLASVLSGACDGEVKIWNLTKRKCIRTIQAHEGFVRGMCTRFCGTSFFTVGDDKTVKQWKMDGPGYGEEEEPLYTVLGKTVYTGIDHHWKDPVFATCGQQVDIWDEQRTSPVCSMNWGFDSISSVKFNPVETFLLGSCASDRNIVLYDMRQATPLKKVILEMRTNTICWNPMEAFNFTAANEDYNLYTFDMRALDTPVMVHMDHVSAVLDVDYSPTGKEFVSASFDKSIRIFPVDKSRSREVY... | [
"GO:0001555",
"GO:0001890",
"GO:0001893",
"GO:0003006",
"GO:0006139",
"GO:0006364",
"GO:0006396",
"GO:0007276",
"GO:0007281",
"GO:0007292",
"GO:0007565",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009888",
"GO:0009987",
"GO:0009994",
"GO:0010467",
"GO:0016049"... | [
"GO:0001555",
"GO:0001890",
"GO:0001893",
"GO:0003006",
"GO:0006139",
"GO:0006364",
"GO:0006396",
"GO:0007276",
"GO:0007281",
"GO:0007292",
"GO:0007565",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009888",
"GO:0009987",
"GO:0009994",
"GO:0010467",
"GO:0016049"... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0030674",
"GO:0060090",
"GO:0140767",
"GO:1990756"
] | [
"GO:0000151",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005730",
"GO:0031461",
"GO:0031974",
"GO:0031981",
"GO:0032991",
"GO:0043226",
"GO:0043227",
"GO:0043228",
"GO:0043229",
"GO:0043231",
"GO:0043232",
"GO:0043233",
"GO:0070013",
"GO:0080008",
"GO:0110165",
"GO:0140535"... | AF-Q6PAC3-F1-model_v6.pdb | 10090.ENSMUSP00000022909 | [
"Q9CVW2",
"Q9JJ12",
"P62082",
"Q9JLT9",
"Q9CZK8",
"Q9D5A8",
"Q9WTU7",
"Q8K3A5",
"Q8R1F7",
"Q9CSE6",
"Q9DB95",
"A0A1Y7VKY1",
"Q99J79",
"Q3THM9",
"Q9D7H3",
"Q8R3N1",
"Q9JJT0",
"Q9DBE9",
"Q9CWK7",
"Q8VE90",
"Q9D0D4",
"Q8VBV3",
"Q99L91",
"Q9DCE5",
"Q8K301",
"Q922H3",
... | [
"IPR051733",
"IPR036322",
"IPR015943",
"IPR001680",
"IPR019775",
"IPR007287"
] | {"IPR036322": [12, 353], "IPR015943": [39, 391], "IPR051733": [1, 444], "IPR007287": [354, 440], "IPR019775": [82, 96], "IPR001680": [55, 362]} | - WD repeat-containing protein 46
- Nucleolar complex protein 4 homolog
- WD repeat domain 36
- U3 small nucleolar RNA-associated protein 4 homolog
- Transducin beta-like protein 3
- Bystin
- WD repeat-containing protein 43
- U3 small nucleolar RNA-interacting protein 2
- KRR1 small subunit processome component homolog... | - IPR051733: WD repeat-containing DCAF13/WDSOF1 (family) [1-444]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [12-353]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [39-391]
- IPR001680: WD40 repeat (repeat) [55-362]
- IPR019775: WD40 repeat... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0023052 (signaling), GO:0065007 (biological regulation), GO:0050896 (response to stimul... |
Q7L014 | Probable ATP-dependent RNA helicase DDX46 | Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs. The 17S U2 SnRNP complex (1) directly participates in early spliceosome assembly and (2) mediates recognition of the intron branch site during pre-mRNA splicing by promoting the s... | Homo sapiens (Human) | 1,031 | Nucleus speckle. Nucleus, Cajal body. Note=Present in Cajal bodies (CBs) and nuclear speckles | MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEP... | [
"GO:0000245",
"GO:0000375",
"GO:0000377",
"GO:0000398",
"GO:0006139",
"GO:0006396",
"GO:0006397",
"GO:0008150",
"GO:0008152",
"GO:0008380",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016043",
"GO:0016070",
"GO:0016071",
"GO:0022607",
"GO:0022613",
"GO:0022618"... | [
"GO:0000245",
"GO:0000375",
"GO:0000377",
"GO:0000398",
"GO:0006139",
"GO:0006396",
"GO:0006397",
"GO:0008150",
"GO:0008152",
"GO:0008380",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0016043",
"GO:0016070",
"GO:0016071",
"GO:0022607",
"GO:0022613",
"GO:0022618"... | [] | [] | AF-Q7L014-F1-model_v6.pdb | 9606.ENSP00000416534 | [
"Q96I25",
"Q9Y4K3",
"Q99968",
"A6PVI3",
"Q9UJD4",
"Q96HN7",
"Q9ULE9",
"P62318",
"Q9ULP3",
"Q59EA1",
"Q9UIS5",
"Q5BKT2",
"Q9UNL1",
"Q9UJY7",
"Q9NTE6",
"Q99974",
"Q9UFQ6",
"Q5TAL3",
"Q9BRD0",
"Q9P2S7",
"Q9BWD2",
"Q9NQT7",
"Q9UH06",
"Q9UJ29",
"Q9NT95",
"Q0D2Q5",
"Q9H... | [
"IPR011545",
"IPR001650",
"IPR014014",
"IPR027417",
"IPR014001",
"IPR056149",
"IPR000629"
] | {"IPR027417": [300, 757], "IPR014014": [372, 400], "IPR014001": [391, 596], "IPR011545": [396, 568], "IPR001650": [592, 753], "IPR056149": [933, 1012], "IPR000629": [527, 535]} | - Splicing factor 3B subunit 1
- Splicing factor 3A subunit 3
- Splicing factor 3A subunit 2
- Splicing factor 3A subunit 1
- Splicing factor 3B subunit 5
- Splicing factor 3B subunit 2
- Splicing factor 3B subunit 3
- Small nuclear ribonucleoprotein Sm D1
- U2 small nuclear ribonucleoprotein A'
- PHD finger-like domai... | - IPR011545: DEAD/DEAH-box helicase domain (domain) [396-568]
- IPR001650: Helicase, C-terminal domain-like (domain) [592-753]
- IPR014014: RNA helicase, DEAD-box type, Q motif (domain) [372-400]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [300-757]
- IPR014001: Helicase su... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0097159 (organic cyclic compound binding), GO:0004386 (helicase activity), GO:0008186 (ATP-dependent activit... |
Q5AFI4 | Cell-surface associated glycoprotein DFI1 | Cell-surface associated glycoprotein that acts as a plasma membrane receptor-type protein which senses the presence of matrix. Binds to calmodulin in response to environmental conditions and initiates a signaling cascade that activates CEK1, thus promoting invasive filamentation. Involved in the maintenance of the cell... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 337 | Cell membrane; Multi-pass membrane protein. Cell septum. Secreted, cell wall. Note=A part becomes cross-linked to the cell wall and thus links the cell wall to the plasma membrane and cytoplasm | MEKLSINNNNNNRRYQSRRFDGITIIRIVVLVFIVTVSTYFVNSYTCNQPHHNHSTRPSHYLPINGTHGLMNNDDSLHNKGAIGHYNTTVSLERRADENNSTTNGLFPSTSSSTFIFTPSSSSSSTFQQSRSSPQTTSTSSFVATTSSFQQETSQTSIPDTTTDFSFSSFSEAPTTSTTSSTSEFSSTPQETSNTVTSTSSTSTSSSSSPTSSPATTSASQHVTTFSSVDNGKTIVVTRTSVISSSPTASNSNNNKNNDNGGGLSHTNRIVVGVVVGVGGSILIGLLAVLFYLRKRNNRDYEGGWTFWRKNEKLGSDEFF... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0005516"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0005516"
] | [] | AF-Q5AFI4-F1-model_v6.pdb | 237561.Q5AFI4 | null | [
"IPR007567"
] | {"IPR007567": [224, 293]} | - IPR007567: Mid2 domain (domain) [224-293] | Molecular Function (MF): GO:0003674 (molecular function), GO:0060089 (molecular transducer activity), GO:0038023 (signaling receptor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0007155 (cell adhesion)
Cellular Component (CC): GO:0005575 (cellular component), GO:... | |
P87170 | CTP-dependent diacylglycerol kinase 1 | CTP-dependent diacylglycerol kinase that catalyzes the phosphorylation of diacylglycerol (DAG) to phosphatidate (PA). Controls phosphatidate levels at the nuclear envelope. Counteracts the activity of PA phosphatase ned1. May be involved in vesicle trafficking between the endoplasmic reticulum and the Golgi apparatus (... | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) | 218 | Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein | MSTKLTWSQWSKKHEIPRKALHTSIGFFALLLQGCGYHAAQIIPVIEIGFIPAFTGDVIRFNWPAFSRLYNRVIGPLMRESEKNAWNGVIFYMIGVWIVLKVFPEEIAVMSVLLLSWCDTTASTVGRKWGKYTPKIAKNKSLAGSLGAFVCGVFCCYVYWGLFRTGPDSLAAQSRIPFPWLCLINGFIGAFAEAMDVWGLDDNLVIPVVSACLLYLIM | [
"GO:0000278",
"GO:0000280",
"GO:0006629",
"GO:0006644",
"GO:0006650",
"GO:0006654",
"GO:0006793",
"GO:0006796",
"GO:0006996",
"GO:0006998",
"GO:0007049",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0008654",
"GO:0009058",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0019637"... | [
"GO:0000278",
"GO:0000280",
"GO:0006629",
"GO:0006644",
"GO:0006650",
"GO:0006654",
"GO:0006793",
"GO:0006796",
"GO:0006996",
"GO:0006998",
"GO:0007049",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0008654",
"GO:0009058",
"GO:0009987",
"GO:0010256",
"GO:0016043",
"GO:0019637"... | [] | [] | AF-P87170-F1-model_v6.pdb | 284812.P87170 | [
"Q09706",
"O59715",
"O42916",
"Q9US27",
"O13901",
"Q9P381",
"Q9UUA6",
"Q9P3V1",
"Q9UUJ6",
"Q9Y827",
"O13909",
"O74975",
"Q9US20"
] | [
"IPR037997"
] | {"IPR037997": [7, 218]} | - Nuclear elongation and deformation protein 1
- Uncharacterized protein C23C11.01
- Uncharacterized acyltransferase C1851.02
- Putative phosphatidate cytidylyltransferase
- Putative lysophosphatidic acid:oleoyl-CoA acyltransferase
- Probable diacylglycerol pyrophosphate phosphatase 1
- Phospholipase D1
- Probable chol... | - IPR037997: CTP-dependent diacylglycerol kinase 1-like (family) [7-218] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016773 (phosphotransferase activity, alcohol group as acceptor), GO:0016301 (kinase activity), GO:0004143 (diacy... |
P37349 | PEP-dependent dihydroxyacetone kinase, phosphoryl donor subunit DhaM | Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues fina... | Escherichia coli (strain K12) | 472 | null | MVNLVIVSHSSRLGEGVGELARQMLMSDSCKIAIAAGIDDPQNPIGTDAVKVMEAIESVADADHVLVMMDMGSALLSAETALELLAPEIAAKVRLCAAPLVEGTLAATVSAASGADIDKVIFDAMHALEAKREQLGLPSSDTEISDTCPAYDEEARSLAVVIKNRNGLHVRPASRLVYTLSTFNADMLLEKNGKCVTPESINQIALLQVRYNDTLRLIAKGPEAEEALIAFRQLAEDNFGETEEVAPPTLRPVPPVSGKAFYYQPVLCTVQAKSTLTVEEEQDRLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSGHHT... | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0042802",
"GO:0042803",
"GO:0046983"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0042802",
"GO:0042803",
"GO:0046983"
] | [] | AF-P37349-F1-model_v6.pdb | 511145.b1198 | [
"P75960",
"Q2M840",
"Q2M8J6",
"P76014",
"P54745",
"P76016",
"P20966",
"P0AA04",
"P94759",
"Q47234",
"P13033",
"P77679",
"P78238",
"Q2M8P1",
"P77439",
"Q2M8P3",
"P75899",
"Q47703",
"P09323",
"P08839",
"Q2M906",
"P76015",
"Q47320",
"Q2M7S2"
] | [
"IPR039643",
"IPR036618",
"IPR036662",
"IPR008731",
"IPR008279",
"IPR035895",
"IPR012844",
"IPR004701",
"IPR001020",
"IPR000032",
"IPR036637"
] | {"IPR036662": [1, 132], "IPR035895": [156, 242], "IPR036618": [265, 388], "IPR036637": [355, 463], "IPR039643": [1, 472], "IPR004701": [1, 135], "IPR012844": [2, 127], "IPR000032": [155, 242], "IPR008731": [258, 368], "IPR008279": [394, 465], "IPR001020": [167, 174]} | - PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL
- PEP-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit DhaK
- Glycerol dehydrogenase
- PTS system glucose-specific EIIA component
- PTS system glucose-specific EIIA component
- PTS system glucose-specific EIIA component
- Multiphosphor... | - IPR039643: Dihydroxyacetone kinase phosphotransferase subunit DhaM (family) [1-472]
- IPR036618: PtsI, HPr-binding domain superfamily (homologous_superfamily) [265-388]
- IPR036662: Phosphotransferase system, mannose-type IIA component superfamily (homologous_superfamily) [1-132]
- IPR008731: Phosphotransferase syste... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0005515 (protein binding), GO:0016772 (transferase activity, transferring phosphorus-containing groups), GO:0016301 (kinase activity)
Biological Process (BP): GO:0008150... |
Q7SXF1 | 7-dehydrocholesterol reductase | Catalyzes the last step of the cholesterol synthesis pathway, which transforms cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol,7- DHC) into cholesterol by reducing the C7-C8 double bond of its sterol core (By similarity). Can also metabolize cholesta-5,7,24-trien-3beta- ol (7-dehydrodemosterol, 7-DHD) to desmosterol, ... | Danio rerio (Zebrafish) (Brachydanio rerio) | 478 | Endoplasmic reticulum membrane; Multi-pass membrane protein | MMASDRVRKRHKGSANGAQTVEKEPSKEPAQWGRAWEVDWFSLSGVILLLCFAPFLVSFFIMACDQYQCSISHPLLDLYNGDATLFTIWNRAPSFTWAAAKIYAIWVTFQVVLYMCVPDFLHKILPGYVGGVQDGARTPAGLINKYEVNGLQCWLITHVLWVLNAQHFHWFSPTIIIDNWIPLLWCTNILGYAVSTFAFIKAYLFPTNPEDCKFTGNMFYNYMMGIEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSYAAKQQELYGYVTNSMILVNVLQAVYVVDFFWNEAWYLKTIDICHDHFGWYLGWGDCVWLPFL... | [
"GO:0001662",
"GO:0002118",
"GO:0002209",
"GO:0006066",
"GO:0006629",
"GO:0006694",
"GO:0006695",
"GO:0006950",
"GO:0006952",
"GO:0007610",
"GO:0008150",
"GO:0008152",
"GO:0008202",
"GO:0008203",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016125",
"GO:0016126",
"GO:0019725"... | [
"GO:0001662",
"GO:0002118",
"GO:0002209",
"GO:0006066",
"GO:0006629",
"GO:0006694",
"GO:0006695",
"GO:0006950",
"GO:0006952",
"GO:0007610",
"GO:0008150",
"GO:0008152",
"GO:0008202",
"GO:0008203",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016125",
"GO:0016126",
"GO:0019725"... | [] | [] | AF-Q7SXF1-F1-model_v6.pdb | 7955.ENSDARP00000136120 | [
"X1WGF3",
"A8WGT1",
"F1R1K0",
"F6P131",
"F1QE73",
"E7F3G8",
"F1QEG3",
"F1R1T7",
"A8WGN9",
"A0A0R4IVV5",
"Q7ZWG9",
"A3KNA7",
"B8A4R3",
"F1Q7H1",
"F6P2A1",
"F1QDN5",
"A0A2R8QIW3",
"A0A0R4IFH5",
"B0UYE4",
"Q08BC5",
"Q7ZW77",
"F1QB82",
"A0A2R8Q2C6",
"B0UYB4",
"Q5U403",
... | [
"IPR018083",
"IPR001171"
] | {"IPR001171": [63, 478], "IPR018083": [216, 465]} | - Lanosterol 14-alpha demethylase
- Ergosterol biosynthesis 28 homolog
- Cholesterol 25-hydroxylase-like protein
- 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7
- Cholesterol 7-alpha-monooxygenase
- Cytochrome P450 7A1
- O-acyltransferase
- Cholesterol 25-hydroxylase-like protein 2
- Cholesterol 25-hy... | - IPR018083: Sterol reductase, conserved site (conserved_site) [216-465]
- IPR001171: Sterol biosynthesis ERG24/DHCR-like (family) [63-478] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016627 (oxidoreductase activity, acting on the CH-CH group of donors), GO:0016628 (oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor)
Biological Proces... |
F1QLP1 | 11-beta-hydroxysteroid dehydrogenase type 2 | Catalyzes the conversion of biologically active 11beta- hydroxyglucocorticoids (11beta-hydroxysteroid) such as cortisol, to inactive 11-ketoglucocorticoids (11-oxosteroid) such as cortisone, in the presence of NAD(+). Cortisol is the primary glucocorticoid in teleosts and is released to increase glucose bioavailability... | Danio rerio (Zebrafish) (Brachydanio rerio) | 414 | Membrane; Multi-pass membrane protein | MEDFAVSFWIYIGVMSIFVGGAVKKFLAFNIGAMPSVVVWLGATLLVERLCALCMPAVLARLVLCVCCWLYFTWATPKPSLPVEDKAVFITGCDSGFGNATAKKLDAMGFEVFATVLNLEGEGAKHLRKVCSSRLTLLQVDITQPQQVQQALLDTKAKLGIRDLWGLVNNAGWCVNIGDAELSLMSNYRGCMEVNFFGTVTVTRTFLPLLRQSKGRIVTISSPSGEHPFPCLASYGASKAALNLFINTLRHELDPWGVKVSTILPSAYKTGQSSNAEYWEKQYKSLLQGLSPNLLEEYGEEYLLETKELFQNYAKTANED... | [
"GO:0003674",
"GO:0003824",
"GO:0016229",
"GO:0016491",
"GO:0016614",
"GO:0016616",
"GO:0033764",
"GO:0070523"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016229",
"GO:0016491",
"GO:0016614",
"GO:0016616",
"GO:0033764",
"GO:0070523"
] | [] | AF-F1QLP1-F1-model_v6.pdb | 7955.ENSDARP00000118501 | [
"F1QVF6",
"F1QSA2",
"O42145",
"A9JRV2",
"Q7T396",
"Q5RIL7",
"A2ATX9",
"Q6PUF3",
"Q6P3H9",
"A0A2R8Q5R7"
] | [
"IPR036291",
"IPR020904",
"IPR002347"
] | {"IPR036291": [80, 373], "IPR002347": [86, 277], "IPR020904": [222, 250]} | - Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
- Hydroxysteroid 11-beta-dehydrogenase 1-like protein
- Hydroxysteroid (11-beta) dehydrogenase 1-like b
- 17-beta-hydroxysteroid dehydrogenase type 3
- Mineralocorticoid receptor
- Aromatase
- Cytochrome P450, family 17, subfamily A, polypep... | - IPR036291: NAD(P)-binding domain superfamily (homologous_superfamily) [80-373]
- IPR020904: Short-chain dehydrogenase/reductase, conserved site (conserved_site) [222-250]
- IPR002347: Short-chain dehydrogenase/reductase SDR (family) [86-277] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016491 (oxidoreductase activity), GO:0016614 (oxidoreductase activity, acting on CH-OH group of donors), GO:0016229 (steroid dehydrogenase activity), GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, N... |
P06965 | Repressor protein of division inhibition gene dicB | This protein is a repressor of division inhibition gene dicB | Escherichia coli (strain K12) | 76 | null | MLKTDALLYFGSKTKLAQAAGIRLASLYSWKGDLVPEGRAMRLQEASGGELQYDPKVYDEYRKTKRAGRLNNENHS | [
"GO:0006355",
"GO:0008150",
"GO:0009889",
"GO:0010468",
"GO:0010556",
"GO:0019219",
"GO:0019222",
"GO:0050789",
"GO:0050794",
"GO:0051252",
"GO:0060255",
"GO:0065007",
"GO:0080090",
"GO:2001141"
] | [
"GO:0006355",
"GO:0008150",
"GO:0009889",
"GO:0010468",
"GO:0010556",
"GO:0019219",
"GO:0019222",
"GO:0050789",
"GO:0050794",
"GO:0051252",
"GO:0060255",
"GO:0065007",
"GO:0080090",
"GO:2001141"
] | [] | [] | AF-P06965-F1-model_v6.pdb | 511145.b1569 | [
"P77571",
"P06966",
"P29008"
] | [
"IPR010982"
] | {"IPR010982": [1, 61]} | - HTH-type transcriptional regulator DicA
- Division inhibition protein DicB
- Uncharacterized protein YdfA
- Uncharacterized protein YdfA | - IPR010982: Lambda repressor-like, DNA-binding domain superfamily (homologous_superfamily) [1-61] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0140110 (transcription regulator activity), GO:1901363 (heterocyclic compound binding), GO:0003700 (DNA-binding transcription factor activity), GO:0097159 (organic cyclic compound binding), GO:0003676 (nucleic acid binding), GO:0001216 (... |
P0ABR1 | DNA damage-inducible protein I | Involved in SOS regulation. Inhibits RecA by preventing RecA to bind ssDNA. Can displace ssDNA from RecA | Escherichia coli (strain K12) | 81 | null | MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRYAAANNLSVIGATKEDKQRISEILQETWESADDWFVSE | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0019899"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0019899"
] | [] | AF-P0ABR1-F1-model_v6.pdb | 511145.b1061 | [
"P76602",
"P33220",
"Q9R7P2",
"P78213",
"Q2M7V8",
"P77798",
"Q47709",
"P04152",
"Q2MC32",
"Q8RNJ5",
"Q2M812",
"P05020",
"P0AG11",
"Q2M6R1"
] | [
"IPR036687",
"IPR010391"
] | {"IPR036687": [1, 81], "IPR010391": [1, 81]} | - Protein RecA
- Protein RecA
- Protein RecA
- Protein RecA
- LexA repressor
- Uncharacterized protein YebG
- Uncharacterized protein YebG
- Uncharacterized protein YebG
- Protein UmuD
- Regulatory protein RecX | - IPR036687: DinI-like superfamily (homologous_superfamily) [1-81]
- IPR010391: DNA damage-inducible protein DinI-like (family) [1-81] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0009987 (cellular process), GO:0009605 (response to external stimulus), GO:0051716 (cellular response to stimulus),... |
Q9Y2G8 | DnaJ homolog subfamily C member 16 | Plays an important role in regulating the size of autophagosomes during the formation process | Homo sapiens (Human) | 782 | Endoplasmic reticulum membrane; Single-pass type IV membrane protein | MEVRKLSISWQFLIVLVLILQILSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKRSNYDQYGDAGENQGYQKQQQQREYRFRHFHENFYFDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPVWKEVIQELEELGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHNAVVRENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHVLLFDQTPIVPLLYKLTAFAYKDYLSFGYVYVGLRGTEEMTRRYNIN... | [
"GO:0006914",
"GO:0006996",
"GO:0007033",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0016043",
"GO:0016236",
"GO:0016243",
"GO:0032535",
"GO:0061919",
"GO:0065007",
"GO:0065008",
"GO:0071840",
"GO:0090066",
"GO:1905037",
"GO:0005575",
"GO:0005622",
"GO:0005737"... | [
"GO:0006914",
"GO:0006996",
"GO:0007033",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009987",
"GO:0016043",
"GO:0016236",
"GO:0016243",
"GO:0032535",
"GO:0061919",
"GO:0065007",
"GO:0065008",
"GO:0071840",
"GO:0090066",
"GO:1905037"
] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031984",
"GO:0042175",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0098827",
"GO:0110165"
] | AF-Q9Y2G8-F1-model_v6.pdb | 9606.ENSP00000365007 | null | [
"IPR013766",
"IPR043361",
"IPR036249",
"IPR018253",
"IPR052448",
"IPR036869",
"IPR001623"
] | {"IPR036869": [27, 137], "IPR036249": [146, 247], "IPR052448": [1, 741], "IPR001623": [28, 104], "IPR013766": [119, 247], "IPR043361": [136, 245], "IPR018253": [70, 89]} | - IPR013766: Thioredoxin domain (domain) [119-247]
- IPR043361: DnaJ homolog subfamily C member 16, TRX domain (domain) [136-245]
- IPR036249: Thioredoxin-like superfamily (homologous_superfamily) [146-247]
- IPR018253: DnaJ domain, conserved site (conserved_site) [70-89]
- IPR052448: DnaJ Homolog Subfamily C Member 16... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0048583 (regulation of response to stimulus), GO:0023051 (regulatio... | |
Q9H819 | DnaJ homolog subfamily C member 18 | (Microbial infection) In case of infection by polyomavirus, involved in the virus endoplasmic reticulum membrane penetration and infection. Regulates the recruitment of DNAJB12:DNAJB14 into SV40-induced foci and all cooperate to guide SV40 across the endoplasmic reticulum membrane. The foci represent the site from whic... | Homo sapiens (Human) | 358 | Endoplasmic reticulum membrane; Single-pass membrane protein | MAATLGSGERWTEAYIDAVRRNKYPEDTPPESHDPCGCCNCMKAQKEKKSENEWTQTRQGEGNSTYSEEQLLGVQRIKKCRNYYEILGVSRDASDEELKKAYRKLALKFHPDKNCAPGATDAFKAIGNAFAVLSNPDKRLRYDEYGDEQVTFTAPRARPYNYYRDFEADITPEELFNVFFGGHFPTGNIHMFSNVTDDTYYYRRRHRHERTQTQKEEEEEKPQTTYSAFIQLLPVLVIVIISVITQLLATNPPYSLFYKSTLGYTISRETQNLQVPYFVDKNFDKAYRGASLHDLEKTIEKDYIDYIQTSCWKEKQQKSE... | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031984",
"GO:0042175",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0098827",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005783",
"GO:0005789",
"GO:0012505",
"GO:0016020",
"GO:0031090",
"GO:0031984",
"GO:0042175",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0098827",
"GO:0110165"
] | AF-Q9H819-F1-model_v6.pdb | 9606.ENSP00000302843 | [
"Q9UPC4",
"Q9H3R6",
"Q9BTZ9",
"Q9UE78"
] | [
"IPR051100",
"IPR018253",
"IPR015399",
"IPR036869",
"IPR001623"
] | {"IPR036869": [77, 191], "IPR051100": [45, 350], "IPR001623": [81, 157], "IPR015399": [250, 348], "IPR018253": [123, 142]} | - Heat shock protein 105 kDa
- Heat shock cognate 71 kDa protein
- Small glutamine-rich tetratricopeptide repeat-containing protein alpha
- Heat shock-related 70 kDa protein 2 | - IPR051100: DnaJ subfamily B/C chaperone co-factors (family) [45-350]
- IPR018253: DnaJ domain, conserved site (conserved_site) [123-142]
- IPR015399: Domain of unknown function DUF1977, DnaJ-like (domain) [250-348]
- IPR036869: Chaperone J-domain superfamily (homologous_superfamily) [77-191]
- IPR001623: DnaJ domain ... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0031072 (heat shock protein binding), GO:0030544 (Hsp70 protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0006457 (protein folding), GO:0071840 (cel... |
O88516 | Delta-like protein 3 | Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm | Mus musculus (Mouse) | 592 | Membrane; Single-pass type I membrane protein | MVSLQVSPLSQTLILAFLLPQALPAGVFELQIHSFGPGPGLGTPRSPCNARGPCRLFFRVCLKPGVSQEATESLCALGAALSTSVPVYTEHPGESAAALPLPDGLVRVPFRDAWPGTFSLVIETWREQLGEHAGGPAWNLLARVVGRRRLAAGGPWARDVQRTGTWELHFSYRARCEPPAVGAACARLCRSRSAPSRCGPGLRPCTPFPDECEAPSVCRPGCSPEHGYCEEPDECRCLEGWTGPLCTVPVSTSSCLNSRVPGPASTGCLLPGPGPCDGNPCANGGSCSETSGSFECACPRGFYGLRCEVSGVTCADGPCF... | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005768",
"GO:0005886",
"GO:0010008",
"GO:0012505",
"GO:0012506",
"GO:0016020",
"GO:0030659",
"GO:0031090",
"GO:0031410",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0071944",
"GO:0097708",
"GO:0098588"... | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005768",
"GO:0005886",
"GO:0010008",
"GO:0012505",
"GO:0012506",
"GO:0016020",
"GO:0030659",
"GO:0031090",
"GO:0031410",
"GO:0031982",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0071944",
"GO:0097708",
"GO:0098588"... | AF-O88516-F1-model_v6.pdb | 10090.ENSMUSP00000103951 | [
"Q7TNT5",
"Q9WV93",
"Q61982",
"E9Q7L5",
"Q8BVI1",
"Q60941",
"Q8C4Z3",
"Q8R3T0",
"Q9JI71",
"Q6PFV7",
"Q9R0X7",
"D4QGC2",
"Q9DC10",
"Q9R1X0"
] | [
"IPR000742",
"IPR050906",
"IPR001881",
"IPR013032",
"IPR011651",
"IPR009030"
] | {"IPR009030": [339, 463], "IPR050906": [175, 369], "IPR011651": [26, 173], "IPR000742": [211, 463], "IPR001881": [277, 463], "IPR013032": [398, 457]} | - Neurogenic locus notch homolog protein 2
- Neurogenic locus notch homolog protein 1
- Neurogenic locus notch homolog protein 4
- Neurogenic locus notch homolog protein 3
- Delta-like protein 1
- Delta-like protein 4
- Recombining binding protein suppressor of hairless
- Transcription factor HES-5
- Beta-1,3-N-acetylg... | - IPR000742: EGF-like domain (domain) [211-463]
- IPR050906: Notch signaling pathway (family) [175-369]
- IPR001881: EGF-like calcium-binding domain (domain) [277-463]
- IPR013032: EGF-like, conserved site (conserved_site) [398-457]
- IPR011651: Notch ligand, N-terminal domain (domain) [26-173]
- IPR009030: Growth fact... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0032502 (developmental process), GO:0048519 (negative regulation of... |
D3ZHH1 | Delta-like protein 4 | Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as we... | Rattus norvegicus (Rat) | 686 | Cell membrane; Single-pass type I membrane protein | MTPGSRSACRWALLLLAVLWPQQRAAGSGIFQLRLQEFANERGMLANGRPCEPGCRTFFRICLKHYQATFSEGPCTFGNVSTPVLGTNSFVIRDKNSGSGRNPLQLPFNFTWPGTFSLNIQAWHTPGDDLRPETSPGNSLISQIIIQGSLAVGKNWKSDEQNNTLTRLRYSYRVVCSDNYYGDSCSRLCKKRDDHFGHYECQPDGSLSCLPGWTGKYCDQPICLSGCHEQNGYCSKPDECNCRPGWQGPLCNECIPHNGCRHGTCTIPWQCACDEGWGGLFCDQDLNYCTHHSPCKNGSTCSNSGPRGYTCTCLPGYTGE... | [
"GO:0001501",
"GO:0001554",
"GO:0001666",
"GO:0002062",
"GO:0003006",
"GO:0006950",
"GO:0007275",
"GO:0007548",
"GO:0008150",
"GO:0008406",
"GO:0008585",
"GO:0009628",
"GO:0009888",
"GO:0009987",
"GO:0022414",
"GO:0022602",
"GO:0030154",
"GO:0032501",
"GO:0032502",
"GO:0033554"... | [
"GO:0001501",
"GO:0001554",
"GO:0001666",
"GO:0002062",
"GO:0003006",
"GO:0006950",
"GO:0007275",
"GO:0007548",
"GO:0008150",
"GO:0008406",
"GO:0008585",
"GO:0009628",
"GO:0009888",
"GO:0009987",
"GO:0022414",
"GO:0022602",
"GO:0030154",
"GO:0032501",
"GO:0032502",
"GO:0033554"... | [] | [] | AF-D3ZHH1-F1-model_v6.pdb | 10116.ENSRNOP00000018970 | [
"D3ZNI5",
"M0R7Q3",
"Q9R172",
"G3V7S6",
"Q6MG89",
"Q04666",
"O08775",
"F1M3B2",
"Q9QW30",
"P53767",
"D4A930",
"Q07008",
"B2B9A9",
"O88671",
"P97677",
"Q91ZT1"
] | [
"IPR000742",
"IPR051830",
"IPR000152",
"IPR001774",
"IPR001881",
"IPR013032",
"IPR011651",
"IPR009030"
] | {"IPR009030": [390, 519], "IPR051830": [367, 625], "IPR011651": [28, 174], "IPR001774": [156, 221], "IPR000742": [175, 519], "IPR001881": [285, 519], "IPR013032": [295, 317], "IPR000152": [340, 351]} | - Neurogenic locus notch homolog protein 1
- Neurogenic locus notch homolog protein 4
- Neurogenic locus notch homolog protein 2
- Neurogenic locus notch homolog protein 3
- Delta-like protein 1
- Delta-like protein 3
- Recombining binding protein suppressor of hairless
- Ephrin-B2
- Vascular endothelial growth factor ... | - IPR000742: EGF-like domain (domain) [175-519]
- IPR051830: Neurogenic locus notch homolog (family) [367-625]
- IPR000152: EGF-type aspartate/asparagine hydroxylation site (ptm) [340-351]
- IPR001774: Delta/Serrate/lag-2 (DSL) protein (domain) [156-221]
- IPR001881: EGF-like calcium-binding domain (domain) [285-519]
-... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0005112 (Notch binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological pr... |
Q61880 | Meiotic recombination protein DMC1/LIM15 homolog | Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks | Mus musculus (Mouse) | 340 | Nucleus. Chromosome | MKEDQVVQEESGFQDDEESLFQDIDLLQKHGINMADIKKLKSVGICTIKGIQMTTRRALCNVKGLSEAKVEKIKEAANKLIEPGFLTAFQYSERRKMVFHITTGSQEFDKLLGGGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGTGGYSGGKIIFIDTENTFRPDRLRDIADRFNVDHEAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTRISLRKGRGELRIAKIYDSPE... | [
"GO:0000150",
"GO:0003674",
"GO:0003824",
"GO:0140097",
"GO:0140640"
] | [] | [
"GO:0000150",
"GO:0003674",
"GO:0003824",
"GO:0140097",
"GO:0140640"
] | [] | AF-Q61880-F1-model_v6.pdb | 10090.ENSMUSP00000023065 | [
"Q9D5T1",
"Q549A7",
"Q62388",
"Q99MW9",
"Q9D513",
"Q9WTK8",
"Q9CUU3",
"Q3UAY5",
"Q9QZG7",
"P27661",
"Q8BUA8",
"Q9Z1Q6",
"O55230",
"Q920F6",
"Q8VEE4",
"Q8K3D3",
"O70157",
"Q9D0A1",
"Q6PFE3",
"Q9Z242",
"P30285",
"Q8K3D4",
"P43352",
"Q496Q5",
"Q9D5T7",
"Q62329",
"Q96... | [
"IPR010995",
"IPR020587",
"IPR027417",
"IPR020588",
"IPR003593",
"IPR011940",
"IPR013632",
"IPR016467"
] | {"IPR010995": [16, 81], "IPR027417": [83, 340], "IPR016467": [18, 340], "IPR011940": [24, 338], "IPR013632": [94, 338], "IPR020588": [97, 270], "IPR003593": [118, 307], "IPR020587": [277, 340]} | - Breast cancer type 2 susceptibility protein homolog
- DNA repair protein RAD51 homolog 1
- Meiotic recombination protein SPO11
- Homologous-pairing protein 2 homolog
- Serine-protein kinase ATM
- Histone H2AX
- MutS protein homolog 4
- DNA repair protein RAD52 homolog
- DNA repair protein XRCC3
- Breast cancer type 1... | - IPR010995: DNA repair Rad51/transcription factor NusA, alpha-helical (homologous_superfamily) [16-81]
- IPR020587: DNA recombination and repair protein RecA, monomer-monomer interface (domain) [277-340]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [83-340]
- IPR020588: DNA... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0022414 (reproductive process), GO:0000003 (reproduction), GO:0032501 (multicellular organismal process), GO:0032502 (developmental process), GO:00099... |
P52496 | DNA ligase 4 | DNA ligase involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair. Not required for the repair of DSBs induced by ionizing radiation or UV light. Has an important role in morphogenesis, positively affecting the capacity to form hyphae | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 928 | Nucleus | MTYFLNDIRPPSPNDITPSFTLLTKELFDKLDGVRKESLGDFRTVTEKKAFIIKTFINTFRTHIGNDIYPSAKLIFPEKSGRIYFIKEVALARLLIKMYKIPKESEDYITLHDWNKSYQRSRRFSIDEKKIRDLPLQASRIISKRRPIVDKLEEYTVPQINSSLDQLALEKVSQGQIDILKPLFDNLSIPEVRWLIHILLNKSILTSMERFFFNTWHPDGYRVFSICNDLQKTLQFSTNPDLRLDPSQLAIHPCFKFKPQLSERLTTSYKTLVKKLQRKHEMDPPYEKKFQELGLENKFYIEEKMDGDRMLLHKDGDSFK... | [
"GO:0008150",
"GO:0030447",
"GO:0040007",
"GO:0044182",
"GO:0003674",
"GO:0003824",
"GO:0003909",
"GO:0016874",
"GO:0016886",
"GO:0140097",
"GO:0140640"
] | [
"GO:0008150",
"GO:0030447",
"GO:0040007",
"GO:0044182"
] | [
"GO:0003674",
"GO:0003824",
"GO:0003909",
"GO:0016874",
"GO:0016886",
"GO:0140097",
"GO:0140640"
] | [] | AF-P52496-F1-model_v6.pdb | 237561.P52496 | [
"A0A1D8PJD1",
"A0A1D8PKE9",
"Q59NG2",
"A0A1D8PI62",
"A0A1D8PSH5",
"A0A1D8PM97",
"Q5AA15",
"Q9P865",
"A0A1D8PRH2",
"A0A1D8PEX6",
"Q59UY8",
"Q5A5N8",
"A0A1D8PGJ5",
"Q5AKX3",
"A0A1D8PLU8",
"Q5AK60",
"Q5A6K8",
"Q5AHZ1",
"A0A1D8PF81",
"Q5AMN0",
"A0A1D8PMZ2",
"A0A1D8PHX3",
"A0A... | [
"IPR036599",
"IPR044125",
"IPR001357",
"IPR029710",
"IPR000977",
"IPR012310",
"IPR016059",
"IPR012340",
"IPR036420",
"IPR012308"
] | {"IPR036599": [17, 247], "IPR012340": [497, 641], "IPR036420": [667, 784], "IPR029710": [16, 927], "IPR000977": [83, 707], "IPR012308": [23, 217], "IPR044125": [248, 499], "IPR012310": [276, 526], "IPR001357": [673, 917], "IPR016059": [302, 494]} | - ATP-dependent DNA helicase II subunit 2
- DNA helicase
- DNA repair and recombination protein RAD52
- Proliferating cell nuclear antigen
- Serine/threonine-protein kinase TOR
- Pso2p
- DNA repair protein RAD51 homolog
- Flap endonuclease 1
- DNA repair and recombination protein RAD52
- Double-strand break repair prot... | - IPR036599: DNA ligase, ATP-dependent, N-terminal domain superfamily (homologous_superfamily) [17-247]
- IPR044125: DNA Ligase 4, adenylation domain (domain) [248-499]
- IPR001357: BRCT domain (domain) [673-917]
- IPR029710: DNA ligase 4 (family) [16-927]
- IPR000977: DNA ligase, ATP-dependent (family) [83-707]
- IPR0... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016874 (ligase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0016886 (ligase activity, forming phosphoric ester bonds), GO:0140097 (catalytic activity, acting on DNA), GO:0003909 (DNA ligase activit... |
Q59Z14 | Deoxyhypusine hydroxylase | Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 318 | Cytoplasm. Nucleus | MSADEVNIDTASLEELRDILINKTGNTKLANRFRALFNLKSVGSEDSDKERAHKAIKYIAECFNDDSELLKHEVAYVLGQTKDLYAAPYLREVLENDNQQCMVRHEAAEALGALGDKESLPLLEKYFKEDPLLEIRQTCELAIERIHWENSEKAKNEVLEKSLYTSIDPAPPLATNDSTSKVEKLKEILNDQDKPLFERYRAMFRLRDIGTDEACLALASGFDDPSALFKHEIAYVFGQMCNPVTVPSLIKVLKDESEAGMVRHEAAEALGSIATDECLPVLQSFLNDSEPVVRDSAIVALDMYEYENSNELEYATVK | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | [] | [] | [
"GO:0005575",
"GO:0030312",
"GO:0031012",
"GO:0062039",
"GO:0062040",
"GO:0071944",
"GO:0110165",
"GO:0140047"
] | AF-Q59Z14-F1-model_v6.pdb | 237561.Q59Z14 | [
"Q5A4M2",
"Q5A4L5",
"Q59NU9",
"A0A1D8PTY4",
"A0A1D8PJD2",
"A0A1D8PFH2"
] | [
"IPR004155",
"IPR016024",
"IPR011989",
"IPR021133",
"IPR027517"
] | {"IPR011989": [9, 313], "IPR016024": [68, 302], "IPR027517": [13, 313], "IPR004155": [68, 289], "IPR021133": [245, 285]} | - Eukaryotic translation initiation factor 5A
- Deoxyhypusine synthase
- Elf1p
- Ribosome biosynthesis protein
- Elongation factor 3
- malate dehydrogenase (oxaloacetate-decarboxylating) | - IPR004155: PBS lyase HEAT-like repeat (repeat) [68-289]
- IPR016024: Armadillo-type fold (homologous_superfamily) [68-302]
- IPR011989: Armadillo-like helical (homologous_superfamily) [9-313]
- IPR021133: HEAT, type 2 (repeat) [245-285]
- IPR027517: Deoxyhypusine hydroxylase (family) [13-313] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0005515 (protein binding), GO:0016491 (oxidoreductase activity), GO:0004497 (monooxygenase activity), GO:0016705 (oxidoreductase activity, acting on p... |
P76334 | Cell division protein DrpB | A non-essential division protein that localizes to the septal ring in low ionic strength medium | Escherichia coli (strain K12) | 100 | Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the septal ring before constriction, only when cells are grown at low ionic strength | MEYGSTKMEERLSRSPGGKLALWAFYTWCGYFVWAMARYIWVMSRIPDAPVSGFESDLGSTAGKWLGALVGFLFMALVGALLGSIAWYTRPRPARSRRYE | [
"GO:0000910",
"GO:0007049",
"GO:0008150",
"GO:0009987",
"GO:0019954",
"GO:0022402",
"GO:0022413",
"GO:0022414",
"GO:0043093",
"GO:0051301"
] | [
"GO:0000910",
"GO:0007049",
"GO:0008150",
"GO:0009987",
"GO:0019954",
"GO:0022402",
"GO:0022413",
"GO:0022414",
"GO:0043093",
"GO:0051301"
] | [] | [] | AF-P76334-F1-model_v6.pdb | 511145.b1963 | [
"P76333"
] | [
"IPR046385"
] | {"IPR046385": [8, 94]} | - Uncharacterized protein YedJ | - IPR046385: Cell division protein DrpB (family) [8-94] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0009987 (cellular process), GO:0051179 (localization), GO:0051234 (establishment of localization), GO:0051641 (cellular localization), GO:0071840 (cel... |
P0DPQ6 | DDIT3 upstream open reading frame protein | [Isoform AltDDIT3]: Product of the upstream open reading frame (uORF) of DDIT3/CHOP that is specifically produced in absence of stress, thereby preventing translation of downstream stress effector DDIT3/CHOP | Homo sapiens (Human) | 34 | Nucleus. Cytoplasm | MLKMSGWQRQSQNQSWNLRRECSRRKCIFIHHHT | [
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | [] | [
"GO:0003674",
"GO:0005488",
"GO:0005515"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0110165"
] | AF-P0DPQ6-F1-model_v6.pdb | 9606.ENSP00000494177 | null | null | NaN | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0022414 (re... | ||
Q9LYT3 | Protein DETOXIFICATION 41 | Acts as a flavonoid/H(+)-antiporter that control the vacuolar sequestration of flavonoids in the seed coat endothelium. Could transport the anthocyanin cyanidin-3-O-glucoside and epicatechin 3'-O-glucoside in vitro | Arabidopsis thaliana (Mouse-ear cress) | 507 | Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast | MSSTETYEPLLTRLHSDSQITERSSPEIEEFLRRRGSTVTPRWWLKLAVWESKLLWTLSGASIVVSVLNYMLSFVTVMFTGHLGSLQLAGASIATVGIQGLAYGIMLGMASAVQTVCGQAYGARQYSSMGIICQRAMVLHLAAAVFLTFLYWYSGPILKTMGQSVAIAHEGQIFARGMIPQIYAFALACPMQRFLQAQNIVNPLAYMSLGVFLLHTLLTWLVTNVLDFGLLGAALILSFSWWLLVAVNGMYILMSPNCKETWTGFSTRAFRGIWPYFKLTVASAVMLCLEIWYNQGLVIISGLLSNPTISLDAISICMYY... | [
"GO:0003674",
"GO:0005215",
"GO:0008324",
"GO:0015075",
"GO:0015078",
"GO:0015291",
"GO:0015297",
"GO:0022804",
"GO:0022857",
"GO:0140968"
] | [] | [
"GO:0003674",
"GO:0005215",
"GO:0008324",
"GO:0015075",
"GO:0015078",
"GO:0015291",
"GO:0015297",
"GO:0022804",
"GO:0022857",
"GO:0140968"
] | [] | AF-Q9LYT3-F1-model_v6.pdb | 3702.Q9LYT3 | [
"Q9FE46",
"Q9LF75",
"Q8VWL1",
"Q9XGN1",
"Q9FEB1",
"Q9FI28",
"Q941R9",
"Q9FN69",
"Q9ZUU0",
"Q9FNV8",
"Q9FNV9",
"Q8LCL0",
"Q43128",
"Q9FMX4",
"Q9SFB0",
"Q9SYD6",
"Q9SD85",
"Q96330",
"Q96323",
"F4JMN7",
"Q9SYA8",
"Q9CAD0",
"Q9SZ97",
"Q9S818",
"Q9FJA2"
] | [
"IPR002528",
"IPR045069"
] | {"IPR045069": [51, 487], "IPR002528": [62, 458]} | - ATPase 10, plasma membrane-type
- Glutathione S-transferase F12
- Transcription factor TT2
- Transcription factor TT8
- Anthocyanidin reductase
- Protein TRANSPARENT TESTA 1
- Leucoanthocyanidin dioxygenase
- Dihydroflavonol 4-reductase
- Protein TRANSPARENT TESTA 16
- Protein TRANSPARENT TESTA GLABRA 1 | - IPR002528: Multi antimicrobial extrusion protein (family) [62-458]
- IPR045069: Multidrug and toxic compound extrusion family, eukaryotic (family) [51-487] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0005215 (transporter activity), GO:0022857 (transmembrane transporter activity), GO:0016787 (hydrolase activity), GO:0015562 (efflux transmembrane transporter activity), GO:0016810 (hydrolase activity, acting on carbon-nitroge... |
P07239 | Dual specificity protein phosphatase OPG106 | Serine/tyrosine phosphatase which down-regulates cellular antiviral response by dephosphorylating activated host STAT1 and blocking interferon (IFN)-stimulated innate immune responses. Dephosphorylates the OPG144 protein | Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain | 171 | Virion. Host cytoplasm. Note=Approximately 200 molecules of OPG106 are packaged within the virion and are essential for the viability of the virus | MDKKSLYKYLLLRSTGDMHKAKSPTIMTRVTNNVYLGNYKNAMDAPSSEVKFKYVLNLTMDKYTLPNSNINIIHIPLVDDTTTDISKYFDDVTAFLSKCDQRNEPVLVHCAAGVNRSGAMILAYLMSKNKESLPMLYFLYVYHSMRDLRGAFVENPSFKRQIIEKYVIDKN | [
"GO:0007154",
"GO:0007165",
"GO:0007166",
"GO:0007259",
"GO:0008150",
"GO:0009987",
"GO:0023052",
"GO:0035821",
"GO:0039502",
"GO:0044003",
"GO:0044068",
"GO:0044403",
"GO:0044419",
"GO:0050789",
"GO:0050794",
"GO:0050896",
"GO:0051701",
"GO:0051716",
"GO:0052027",
"GO:0052029"... | [
"GO:0007154",
"GO:0007165",
"GO:0007166",
"GO:0007259",
"GO:0008150",
"GO:0009987",
"GO:0023052",
"GO:0035821",
"GO:0039502",
"GO:0044003",
"GO:0044068",
"GO:0044403",
"GO:0044419",
"GO:0050789",
"GO:0050794",
"GO:0050896",
"GO:0051701",
"GO:0051716",
"GO:0052027",
"GO:0052029"... | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0110165"
] | null | null | null | [
"IPR003595",
"IPR052103",
"IPR016130",
"IPR000387",
"IPR029021",
"IPR020422",
"IPR000340"
] | {"IPR029021": [1, 171], "IPR052103": [22, 164], "IPR020422": [23, 171], "IPR000340": [34, 166], "IPR003595": [68, 168], "IPR000387": [86, 160], "IPR016130": [108, 118]} | - IPR003595: Protein-tyrosine phosphatase, catalytic (domain) [68-168]
- IPR052103: Dual Specificity Protein Phosphatases (family) [22-164]
- IPR016130: Protein-tyrosine phosphatase, active site (active_site) [108-118]
- IPR000387: Tyrosine-specific protein phosphatases domain (domain) [86-160]
- IPR029021: Protein-tyr... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0044237 (cellular metabolic process), GO:0071704 (organic substance metabolic process),... | |
Q9JJ79 | Cytoplasmic dynein 2 heavy chain 1 | May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis. May play a role in transport between endoplasmic reticulum and Golgi or organization of the Golgi in cells (By similarity) | Rattus norvegicus (Rat) | 4,306 | Cytoplasm, cytoskeleton, cilium axoneme. Cell membrane; Peripheral membrane protein. Cytoplasm. Note=Localizes to the apical cytoplasm. May localize to Golgi apparatus, cytoplasmic vesicle and endoplasmic reticulum (By similarity) | MAGSLSDVRKLFLFTTTQNYFGLRPELWDQTPLSNCPEVNNFLDDGNQMLLRVQRSDAGLAFSNTIDFDDTKDKVLVFFKLRPEVITDGNLHTNILVSSMLESPINSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGVVLRKSDTNLPKLKLKEDDTRGILTPSDEFQFWIEQAHRGSKQISKERASYFKELFETIAREFYNLDSLSLLEVVDLVETTRDVVDDVWRQAEHDHYPESRMLHLLDVIGGSFGRFVQKKLGSLKLWEDPYYLVKENLKAGISICEQWVIVCSHLTGQVWQRYVPHPWKSEKYF... | [
"GO:0006996",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022607",
"GO:0030030",
"GO:0030031",
"GO:0044085",
"GO:0044782",
"GO:0060271",
"GO:0070925",
"GO:0071840",
"GO:0120031",
"GO:0120036",
"GO:0005575",
"GO:0005622",
"GO:0005856",
"GO:0005868",
"GO:0005875",
"GO:0015630"... | [
"GO:0006996",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022607",
"GO:0030030",
"GO:0030031",
"GO:0044085",
"GO:0044782",
"GO:0060271",
"GO:0070925",
"GO:0071840",
"GO:0120031",
"GO:0120036"
] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005856",
"GO:0005868",
"GO:0005875",
"GO:0015630",
"GO:0030286",
"GO:0032991",
"GO:0043226",
"GO:0043228",
"GO:0043229",
"GO:0043232",
"GO:0045177",
"GO:0110165",
"GO:1902494"
] | null | 10116.ENSRNOP00000043252 | [
"Q15701",
"A0A096MK92",
"D4A0A0",
"Q66HB3",
"Q6P9T8",
"D4A333",
"A0A0G2QC64",
"Q78P75",
"M0R8B6",
"A0A0G2JWE4",
"A0A0G2JZL6",
"Q9D812",
"Q9CY33",
"F1LV01",
"Q62698",
"F1LUM5",
"Q4QQV0",
"Q3KRE8",
"D3ZB99",
"F1LY69",
"A0A0G2K5Q6",
"A0A0G2K1X3",
"A0A0G2KB78",
"P85108",
... | [
"IPR043157",
"IPR042219",
"IPR041658",
"IPR042228",
"IPR043160",
"IPR024743",
"IPR035699",
"IPR013602",
"IPR042222",
"IPR049400",
"IPR054354",
"IPR013594",
"IPR041228",
"IPR004273",
"IPR027417",
"IPR024317",
"IPR026983",
"IPR003593",
"IPR035706"
] | {"IPR042222": [1259, 1424], "IPR042228": [1425, 1521], "IPR027417": [1666, 3830], "IPR043157": [1819, 1935], "IPR042219": [3831, 3998], "IPR043160": [4175, 4306], "IPR026983": [192, 4305], "IPR013594": [200, 652], "IPR013602": [1120, 1518], "IPR035699": [1651, 1986], "IPR003593": [1684, 2431], "IPR049400": [2121, 2216]... | - Cytoplasmic dynein 2 light intermediate chain 1
- Cytoplasmic dynein 2 intermediate chain 1
- Cytoplasmic dynein 2 intermediate chain 2
- Cytoplasmic dynein 1 light intermediate chain 1
- Dynein light chain 1, cytoplasmic
- Dynein light chain 1, cytoplasmic
- Dynein light chain 1, cytoplasmic
- Dynein light chain 1, ... | - IPR043157: Dynein heavy chain, AAA1 domain, small subdomain (homologous_superfamily) [1819-1935]
- IPR042219: Dynein heavy chain AAA lid domain superfamily (homologous_superfamily) [3831-3998]
- IPR041658: Dynein heavy chain AAA lid domain (domain) [3861-4000]
- IPR042228: Dynein heavy chain, linker, subdomain 3 (hom... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus), GO:0042221 (response to chemical), GO:0010033 (response to organic substance), GO:1901700 (response to oxygen-containi... |
G1UB67 | Transcriptional regulator DEF1 | Transcriptional regulator involved in extension of germ tubes into elongated hyphae and maintenance of filamentous growth. Regulates expression of UME6. Acts in a pathway that regulates maintenance of hyphal growth by repressing hyphal-to-yeast transition and allows dissemination within host epithelial tissues. Dispens... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 887 | Nucleus | MERRQFNTSNIRNGTGRPRKTPRSKLYMVYPPLSGEDSTNPEPEEGSSQENNPTEPSSSQSNSVQNQDQSEDQSQLPQQESNTQQESNTQQESNTPSPRASNTSTETPAPLSPIQPGIRNIPSGLLLPQEKVGRLMGYPFYRDFNFTLNPERYQKLIYVFQILKNAARNHRNGASLLRKYFSLARRSKRTTDMFVTTIEEMRKRSLENSRKRELEEAQEREESNKRQHTESSAEPNAESSTESTTESNAESGAEPNAEPSAESTTESNVESGAEPNAESGAESGAEPTAESNAELKQRIWEILSYRLEQSNNETNNTGES... | [
"GO:0007154",
"GO:0007155",
"GO:0007267",
"GO:0008150",
"GO:0009372",
"GO:0009595",
"GO:0009607",
"GO:0009987",
"GO:0010570",
"GO:0010810",
"GO:0010811",
"GO:0023052",
"GO:0030155",
"GO:0030447",
"GO:0031589",
"GO:0040007",
"GO:0040008",
"GO:0042710",
"GO:0043708",
"GO:0043709"... | [
"GO:0007154",
"GO:0007155",
"GO:0007267",
"GO:0008150",
"GO:0009372",
"GO:0009595",
"GO:0009607",
"GO:0009987",
"GO:0010570",
"GO:0010810",
"GO:0010811",
"GO:0023052",
"GO:0030155",
"GO:0030447",
"GO:0031589",
"GO:0040007",
"GO:0040008",
"GO:0042710",
"GO:0043708",
"GO:0043709"... | [] | [] | AF-G1UB67-F1-model_v6.pdb | 237561.G1UB67 | [
"Q59ME1",
"Q5AI28",
"A0A1D8PPL1",
"A0A1D8PQK3",
"Q5A886",
"Q59WH0",
"Q59TL7",
"A0A1D8PPU7",
"Q59XB5",
"A0A1D8PU74",
"Q59VN4",
"Q5ABE2",
"A0A1D8PNT2",
"Q59TP1",
"Q874L3"
] | null | NaN | - Transcriptional regulatory protein UME6
- Histone acetyltransferase
- Transcriptional adapter 2
- Transcription initiation factor TFIID subunit 9
- Histone acetyltransferase
- Transcription initiation factor TFIID subunit 10
- Enhanced filamentous growth protein 1
- Deubiquitination module subunit
- Histone H4
- Hyph... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0140096 (catalytic activity, acting on a protein), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0061733 (peptide-lysine-N-acetyltransferase activity), GO:0004402 (histone acetyltransferase activ... | |
Q78T81 | Early estrogen-induced gene 1 protein | Key component of TNFSF11/RANKL- and TNF-induced osteoclastogenesis pathways, thereby mediates bone resorption in pathological bone loss conditions. Required for TNFSF11/RANKL-induced osteoclastogenesis via its interaction with TNFRSF11A/RANK, thereby facilitates the downsteam transcription of NFATC1 and activation of P... | Mus musculus (Mouse) | 392 | Nucleus. Cytoplasm. Membrane raft | MAFLMKKKKFKFQTTFTLEELTAVPFVNGVLFCKVRLLDGGDFVSLSSREEVQENCVRWRKRFTFVCKMSANPATGLLDPCIFRVSVRKELKGGKAYSKLGFTDLNLAEFAGSGSTVRCCLLEGYDTKNTRQDNSILKVTIGMFLLSGDPCFKTPPSTAKSISIPGQDSSLQLTCKGGGTSSGGSSSTNSLTGSRPPKTRPTILGSGLPEEPDQSLSSPEEVFHSGHSRNSSYASQQSKLSGYSTEHSRSSSLSDLTHRRNTSTSSSASGGLSMAVEGPEGMEREHRPSEKPPRPPEKPPRPPRPLHLSDRSFRRKKDSV... | [
"GO:0002682",
"GO:0002684",
"GO:0002761",
"GO:0002763",
"GO:0008150",
"GO:0010720",
"GO:0045595",
"GO:0045597",
"GO:0045637",
"GO:0045639",
"GO:0045670",
"GO:0045672",
"GO:0048518",
"GO:0048522",
"GO:0050789",
"GO:0050793",
"GO:0050794",
"GO:0051094",
"GO:0051239",
"GO:0051240"... | [
"GO:0002682",
"GO:0002684",
"GO:0002761",
"GO:0002763",
"GO:0008150",
"GO:0010720",
"GO:0045595",
"GO:0045597",
"GO:0045637",
"GO:0045639",
"GO:0045670",
"GO:0045672",
"GO:0048518",
"GO:0048522",
"GO:0050789",
"GO:0050793",
"GO:0050794",
"GO:0051094",
"GO:0051239",
"GO:0051240"... | [
"GO:0003674",
"GO:0005488",
"GO:0005515"
] | [
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005737",
"GO:0016020",
"GO:0043226",
"GO:0043227",
"GO:0043229",
"GO:0043231",
"GO:0045121",
"GO:0098857",
"GO:0110165"
] | AF-Q78T81-F1-model_v6.pdb | 10090.ENSMUSP00000044731 | null | [
"IPR039931",
"IPR019448"
] | {"IPR039931": [1, 391], "IPR019448": [2, 152]} | - IPR039931: EEIG1/2-like (family) [1-391]
- IPR019448: NT-type C2 domain (domain) [2-152] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0032502 (developmental process), GO:0051179 (localization), GO:0032501 (multicellular organismal process), GO:0051234 (establishment of localization),... | |
Q59QD6 | Elongation factor 1-alpha 2 | This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 458 | Cytoplasm | MGKEKTHVNVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYHVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGTGEFEAGISKDGQTREHALLAYTLGVKQLIVAVNKMDSVKWDKNRFEEIIKETSNFVKKVGYNPKTVPFVPISGWNGDNMIEPSTNCPWYKGWEKETKSGKVTGKTLLEAIDAIEPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGIIKAGMVVTFAPAGVTTEVKSVEMHHEQLAEGVPGDNVGFNVKNVSVKEIRR... | [
"GO:0008150",
"GO:0044403",
"GO:0044419",
"GO:0051701",
"GO:0003674",
"GO:0005488",
"GO:0005515",
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0030445",
"GO:0030446",
"GO:0071944",
"GO:0110165"
] | [
"GO:0008150",
"GO:0044403",
"GO:0044419",
"GO:0051701"
] | [
"GO:0003674",
"GO:0005488",
"GO:0005515"
] | [
"GO:0005575",
"GO:0005618",
"GO:0009277",
"GO:0009986",
"GO:0030312",
"GO:0030445",
"GO:0030446",
"GO:0071944",
"GO:0110165"
] | AF-Q59QD6-F1-model_v6.pdb | 237561.Q59QD6 | [
"A0A1D8PLC9",
"Q9P8C6",
"A0A1D8PF08",
"Q5AGZ7",
"A0A1D8PTY4",
"A0A1D8PCX8",
"Q5A4X5",
"A0A1D8PM35",
"A0A1D8PK22",
"Q5A500",
"A0A1D8PSV5",
"A0A1D8PPS1",
"Q5AI59",
"A0A1D8PQQ5",
"Q59LS1",
"Q59S46",
"A0A1D8PNN8",
"Q5AEN2",
"A0A1D8PRG5",
"Q5A4L5",
"A0A1D8PSD0",
"Q59NU9",
"Q9P... | [
"IPR000795",
"IPR004539",
"IPR009000",
"IPR050100",
"IPR027417",
"IPR031157",
"IPR009001",
"IPR004161",
"IPR054696"
] | {"IPR027417": [1, 259], "IPR009000": [241, 332], "IPR009001": [335, 439], "IPR004539": [1, 444], "IPR050100": [1, 443], "IPR000795": [5, 240], "IPR004161": [258, 324], "IPR054696": [337, 437], "IPR031157": [61, 76]} | - Cam1-1p
- Translation elongation factor EF1B gamma
- Tef4p
- Transcription factor SKN7
- Translation elongation factor 1 subunit beta
- Elongation factor 3
- Small ribosomal subunit protein uS5
- Adenylyl-sulfate kinase
- Translation termination factor eRF1
- Small ribosomal subunit protein eS1 | - IPR000795: Translational (tr)-type GTP-binding domain (domain) [5-240]
- IPR004539: Translation elongation factor EF1A, eukaryotic/archaeal (family) [1-444]
- IPR009000: Translation protein, beta-barrel domain superfamily (homologous_superfamily) [241-332]
- IPR050100: Translation factor GTPase superfamily members (f... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0044419 (biological process involved in interspecies interaction between organisms), GO:0044403 (biological process involved in symbiotic interaction)... |
P55823 | Elongation factor 2 | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectiv... | Oryctolagus cuniculus (Rabbit) | 857 | Cytoplasm. Nucleus. Note=Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C- terminal cleavage product | MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLD... | [
"GO:0003674",
"GO:0003746",
"GO:0003824",
"GO:0003924",
"GO:0005488",
"GO:0005515",
"GO:0016462",
"GO:0016787",
"GO:0016817",
"GO:0016818",
"GO:0017111",
"GO:0180051"
] | [] | [
"GO:0003674",
"GO:0003746",
"GO:0003824",
"GO:0003924",
"GO:0005488",
"GO:0005515",
"GO:0016462",
"GO:0016787",
"GO:0016817",
"GO:0016818",
"GO:0017111",
"GO:0180051"
] | [] | AF-P55823-F1-model_v6.pdb | null | null | [
"IPR000795",
"IPR005517",
"IPR009000",
"IPR020568",
"IPR000640",
"IPR027417",
"IPR014721",
"IPR035647",
"IPR041095",
"IPR031157",
"IPR004161",
"IPR005225"
] | {"IPR027417": [3, 359], "IPR009000": [360, 497], "IPR035647": [500, 842], "IPR020568": [577, 741], "IPR014721": [584, 737], "IPR000795": [17, 362], "IPR005225": [19, 164], "IPR004161": [411, 484], "IPR041095": [503, 564], "IPR005517": [621, 737], "IPR000640": [739, 828], "IPR031157": [58, 73]} | - IPR000795: Translational (tr)-type GTP-binding domain (domain) [17-362]
- IPR005517: Translation elongation factor EFG/EF2, domain IV (domain) [621-737]
- IPR009000: Translation protein, beta-barrel domain superfamily (homologous_superfamily) [360-497]
- IPR020568: Ribosomal protein uS5 domain 2-type superfamily (hom... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0009893 (po... | |
P25997 | Elongation factor 3 | Ribosome-dependent ATPase that functions in cytoplasmic translation elongation (By similarity). Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis (By similarity). Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has red... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 1,050 | Cytoplasm | MSAASESKYSTEVLSELLSKLQVADNKDEAASNISTFLNSSIVEHDVPVEFFEDLKKQIQSKDAKVSLAALDAYKHIASTNGLSPSVEPYVVDLVSEVAVKAGDKNKDVQTAASDALLAIASAITPTAVKAILPKLIDNLTNTNKWTEKVAILRAVSQLVDTAKAQIALRMPELIPVLSESMWDTKKEVKEAATATMTKSTETIDNKDIEKFIPQLISCIAKPTEVPETVHLLGATTFVSEVTMATLSIMAPLLSRGLAERDTAIKRKAAVIVDNMCKLVEDPQIVAPFMDKLLPGLKNNFANMADPEAREVTQRALNTL... | [
"GO:0006412",
"GO:0006414",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0019538",
"GO:0043170",
"GO:0044238",
"GO:0160307",
"GO:0003674",
"GO:0003746",
"GO:0003824",
"GO:0016462",
"GO:0016787",
"GO:0016817",
"GO:0016818",
"GO:0016887"... | [
"GO:0006412",
"GO:0006414",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0019538",
"GO:0043170",
"GO:0044238",
"GO:0160307"
] | [
"GO:0003674",
"GO:0003746",
"GO:0003824",
"GO:0016462",
"GO:0016787",
"GO:0016817",
"GO:0016818",
"GO:0016887",
"GO:0017111",
"GO:0140657",
"GO:0180051"
] | [
"GO:0005575",
"GO:0005618",
"GO:0005886",
"GO:0009277",
"GO:0009986",
"GO:0016020",
"GO:0030312",
"GO:0030445",
"GO:0071944",
"GO:0110165"
] | AF-P25997-F1-model_v6.pdb | 237561.P25997 | [
"Q59LL5",
"A0A1D8PGY0",
"Q5AKW2",
"A0A1D8PTC7",
"Q5AJF7",
"A0A1D8PHX3",
"A0A1D8PRJ6",
"A0A1D8PFZ8",
"Q5AA46",
"A0A1D8PQJ8",
"A0A1D8PF45",
"Q5AAS9",
"A0A1D8PM35",
"A0A1D8PK22",
"A0A1D8PPL1",
"Q59VH3",
"A0A1D8PPS1",
"A0A1D8PQM9",
"A0A1D8PSV5",
"Q5A743",
"A0A1D8PPE0",
"Q59V85"... | [
"IPR047036",
"IPR016024",
"IPR011989",
"IPR027417",
"IPR003593",
"IPR021133",
"IPR015688",
"IPR040533",
"IPR003439",
"IPR017871",
"IPR047038",
"IPR050611"
] | {"IPR011989": [2, 331], "IPR016024": [29, 1041], "IPR047036": [332, 421], "IPR027417": [423, 980], "IPR047038": [767, 876], "IPR050611": [649, 980], "IPR040533": [339, 414], "IPR003439": [429, 998], "IPR003593": [458, 975], "IPR015688": [799, 866], "IPR017871": [549, 916], "IPR021133": [174, 212]} | - Elf1p
- Large ribosomal subunit protein uL18
- Cam1-1p
- Translation elongation factor EF1B gamma
- Tef4p
- Small ribosomal subunit protein uS4
- Large ribosomal subunit protein uL3
- Small ribosomal subunit protein uS5
- Small ribosomal subunit protein uS4m
- Small ribosomal subunit protein uS3 | - IPR047036: Elongation factor 3, four helical bundle domain superfamily (homologous_superfamily) [332-421]
- IPR016024: Armadillo-type fold (homologous_superfamily) [29-1041]
- IPR011989: Armadillo-like helical (homologous_superfamily) [2-331]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologou... | Molecular Function (MF): GO:0003674 (molecular function), GO:0045182 (translation regulator activity), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0140657 (ATP-dependent activity), GO:0016887 (ATP hydrolysis activity), GO:0097159 (organic cyclic compound binding), GO:0090079 (translation regulator activit... |
Q59X67 | Enhanced filamentous growth protein 1 | Transcriptional regulator of the switch between 2 heritable states, the white and opaque states. These 2 cell types differ in many characteristics, including cell structure, mating competence, and virulence. Each state is heritable for many generations, and switching between states occurs stochastically, at low frequen... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 550 | Nucleus | MSTYSIPYYNQMNGNYNNGMPQQTTAANQQAFPQQQQPTTTGNASQQQQQAAATAAAAAVQQPYNYMFYQQQGQPGQQTGQTAGQQQQQQQQQQQYDYNTYNRYQYPAATSQGNYYQQTIPNQLSQPQPQHYNGSNRNYTSAPSGAPIPSNSTSGPSQQPPLPGQQAVPIPPHVSTMQQPTPVQDTLNASSTSTVGQFQPPGIRPRVTTTMWEDEKTLCYQVDANNVSVVRRADNNMINGTKLLNVAQMTRGRRDGILKSEKVRHVVKIGSMHLKGVWIPFERALAMAQREQIVDMLYPLFVRDIKRVIQTGVTPNAAAA... | [
"GO:0000122",
"GO:0000128",
"GO:0000902",
"GO:0001410",
"GO:0001558",
"GO:0002831",
"GO:0002833",
"GO:0003006",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0007124",
"GO:0007155",
"GO:0007584",
"GO:0007618",
"GO:0008150",
"GO:0009267",
"GO:0009268",
"GO:0009605",
"GO:0009607"... | [
"GO:0000122",
"GO:0000128",
"GO:0000902",
"GO:0001410",
"GO:0001558",
"GO:0002831",
"GO:0002833",
"GO:0003006",
"GO:0006355",
"GO:0006357",
"GO:0006950",
"GO:0007124",
"GO:0007155",
"GO:0007584",
"GO:0007618",
"GO:0008150",
"GO:0009267",
"GO:0009268",
"GO:0009605",
"GO:0009607"... | [
"GO:0001216",
"GO:0003674",
"GO:0003676",
"GO:0003677",
"GO:0003700",
"GO:0005488",
"GO:0043565",
"GO:0140110"
] | [
"GO:0000785",
"GO:0005575",
"GO:0005622",
"GO:0005634",
"GO:0005694",
"GO:0043226",
"GO:0043227",
"GO:0043228",
"GO:0043229",
"GO:0043231",
"GO:0043232",
"GO:0110165"
] | AF-Q59X67-F1-model_v6.pdb | 237561.Q59X67 | [
"Q59WZ4",
"Q5ALC8",
"Q9UW14",
"Q5AB65",
"Q59XU5",
"Q5A271",
"Q59TL7",
"A0A1D8PHU1",
"Q59LY1",
"Q5AP71",
"Q7Z883",
"Q59PG4",
"Q5A0W9",
"Q5ABE2",
"A0A1D8PFP2",
"Q5ANB1",
"Q874L3",
"G1UB67",
"Q59U34",
"Q59S18",
"Q59ME1",
"Q5A8T4",
"Q5ANJ4",
"Q5A0E5",
"Q6LC13",
"Q5ACU9"... | [
"IPR036887",
"IPR029790",
"IPR018004",
"IPR003163"
] | {"IPR036887": [206, 333], "IPR029790": [1, 543], "IPR003163": [206, 312], "IPR018004": [225, 311]} | - cAMP-dependent protein kinase
- cAMP-dependent protein kinase
- Transcriptional regulator of filamentous growth FLO8
- Transcription activator TEC1
- Zinc cluster transcription factor CZF1
- Transcriptional regulator NRG1
- Transcriptional regulator EFH1
- Transcriptional repressor TUP1
- Transcriptional repressor TU... | - IPR036887: HTH APSES-type DNA-binding domain superfamily (homologous_superfamily) [206-333]
- IPR029790: EFG1/Phd1/StuA family (family) [1-543]
- IPR018004: KilA/APSES-type HTH, DNA-binding (domain) [225-311]
- IPR003163: Transcription regulator HTH, APSES-type DNA-binding domain (domain) [206-312] | Molecular Function (MF): GO:0003674 (molecular function), GO:0140110 (transcription regulator activity), GO:0003700 (DNA-binding transcription factor activity)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0048518 (positive regulation of biological process), GO:0050789... |
P0A6M8 | Elongation factor G | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl- tRNA and P-site-bound deacylated tRNA move to the P and E sites, respecti... | Escherichia coli (strain K12) | 704 | Cytoplasm | MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSAL... | [
"GO:0006412",
"GO:0006414",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0019538",
"GO:0043170",
"GO:0044238",
"GO:0160307"
] | [
"GO:0006412",
"GO:0006414",
"GO:0008150",
"GO:0008152",
"GO:0009058",
"GO:0009059",
"GO:0009987",
"GO:0010467",
"GO:0019538",
"GO:0043170",
"GO:0044238",
"GO:0160307"
] | [] | [] | AF-P0A6M8-F1-model_v6.pdb | 511145.b3340 | [
"Q9R2E5",
"Q2M9V1",
"P0A6P1",
"P0A7U7",
"P77006",
"P04079",
"Q2M811",
"Q2M8Y2",
"Q2M6H4",
"Q2M850",
"Q2MCC5",
"Q2MBV3",
"Q2M6W3",
"Q8XED3",
"Q2M941",
"Q2M6W9",
"Q2MAF4",
"Q59429",
"Q2M6Y6",
"Q2M706",
"Q8XE90",
"Q2M8S4",
"Q2MBZ0",
"Q2M6X4",
"Q2M6A5",
"Q2M6W0",
"Q2M... | [
"IPR000795",
"IPR005517",
"IPR047872",
"IPR009000",
"IPR020568",
"IPR000640",
"IPR027417",
"IPR014721",
"IPR035647",
"IPR005225",
"IPR041095",
"IPR031157",
"IPR009022",
"IPR004161",
"IPR004540",
"IPR035649"
] | {"IPR027417": [1, 298], "IPR009000": [271, 411], "IPR035647": [411, 700], "IPR020568": [486, 610], "IPR014721": [492, 699], "IPR004540": [1, 703], "IPR000795": [8, 290], "IPR005225": [10, 187], "IPR004161": [331, 398], "IPR041095": [411, 485], "IPR009022": [412, 487], "IPR005517": [486, 609], "IPR047872": [490, 609], "... | - Small ribosomal subunit protein uS2
- Small ribosomal subunit protein uS2
- Small ribosomal subunit protein uS2
- Large ribosomal subunit protein uL13
- Small ribosomal subunit protein uS13
- Large ribosomal subunit protein uL18
- Small ribosomal subunit protein uS10
- Small ribosomal subunit protein uS7
- Large ribo... | - IPR000795: Translational (tr)-type GTP-binding domain (domain) [8-290]
- IPR005517: Translation elongation factor EFG/EF2, domain IV (domain) [486-609]
- IPR047872: Elongation factor G, domain IV (domain) [490-609]
- IPR009000: Translation protein, beta-barrel domain superfamily (homologous_superfamily) [271-411]
- I... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0036094 (small molecule binding), GO:1901363 (heterocyclic compound binding), GO:0043167 (ion binding), GO:0097159 (organic cyclic compound binding), GO:0097367 (carbohydrate derivative binding), GO:1901265 (nucleoside phosphate binding)... |
Q8N6R0 | eEF1A lysine and N-terminal methyltransferase | Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2) at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and E... | Homo sapiens (Human) | 699 | Cytoplasm. Nucleus. Mitochondrion | MNLLPKSSREFGSVDYWEKFFQQRGKKAFEWYGTYLELCGVLHKYIKPREKVLVIGCGNSELSEQLYDVGYRDIVNIDISEVVIKQMKECNATRRPQMSFLKMDMTQMEFPDASFQVVLDKGTLDAVLTDEEEKTLQQVDRMLAEVGRVLQVGGRYLCISLAQAHILKKAVGHFSREGWMVRVHQVANSQDQVLEAEPQFSLPVFAFIMTKFRPVPGSALQIFELCAQEQRKPVRLESAERLAEAVQERQQYAWLCSQLRRKARLGSVSLDLCDGDTGEPRYTLHVVDSPTVKPSRDNHFAIFIIPQGRETEWLFGMDEG... | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-Q8N6R0-F1-model_v6.pdb | 9606.ENSP00000354920 | [
"Q9UFW1",
"Q9HCE5",
"Q5JPI9",
"P54821",
"Q9H4E2"
] | [
"IPR051419",
"IPR029063",
"IPR041698"
] | {"IPR029063": [9, 685], "IPR051419": [10, 314], "IPR041698": [52, 147]} | - N(6)-adenosine-methyltransferase non-catalytic subunit METTL14
- Pre-mRNA-splicing regulator WTAP
- Paired mesoderm homeobox protein 1
- EEF1A lysine methyltransferase 2
- Protein virilizer homolog | - IPR051419: Lysine/N-terminal Methyltransferase Superfamily (family) [10-314]
- IPR029063: S-adenosyl-L-methionine-dependent methyltransferase superfamily (homologous_superfamily) [9-685]
- IPR041698: Methyltransferase domain 25 (domain) [52-147] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0048519 (negative regulation of biological process), GO:0019222 (re... |
Q6PC64 | Very long chain fatty acid elongase 6 | Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates... | Danio rerio (Zebrafish) (Brachydanio rerio) | 266 | Endoplasmic reticulum membrane; Multi-pass membrane protein | MSVLALQEYEFERQFNEDEAIRWMQENWKKSFLFSALYAACILGGRHVMKQREKFELRKPLVLWSLTLAAFSIFGAIRTGGYMVNILMTKGLKQSVCDQSFYNGPVSKFWAYAFVLSKAPELGDTLFIVLRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYLVHAVMYSYYALRAAGFKISRKFAMFITLTQITQMVMGCVVNYLVYLWMQQGQECPSHVQNIVWSSLMYLSYFVLFCQFFFEAYITKRKSNAAKKSQ | [
"GO:0006082",
"GO:0006629",
"GO:0006631",
"GO:0006633",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0030497",
"GO:0032787",
"GO:0043436",
"GO:0044238",
"GO:0044281",
"GO:0044283",
"GO:0046394",
"GO:0072330"
] | [
"GO:0006082",
"GO:0006629",
"GO:0006631",
"GO:0006633",
"GO:0008150",
"GO:0008152",
"GO:0008610",
"GO:0009058",
"GO:0009987",
"GO:0016053",
"GO:0019752",
"GO:0030497",
"GO:0032787",
"GO:0043436",
"GO:0044238",
"GO:0044281",
"GO:0044283",
"GO:0046394",
"GO:0072330"
] | [] | [] | AF-Q6PC64-F1-model_v6.pdb | 7955.ENSDARP00000096379 | [
"Q8AX86",
"B8JK95",
"A2BFP6",
"F1QG70",
"F1R7W6",
"Q7ZUN4",
"Q6QA33",
"Q9DEX7",
"E7FFJ3"
] | [
"IPR002076",
"IPR030457",
"IPR033675"
] | {"IPR033675": [1, 266], "IPR002076": [14, 260], "IPR030457": [135, 143]} | - Elongation of very long chain fatty acids protein 5
- 3-oxoacyl-[acyl-carrier-protein] synthase
- Fatty acid synthase
- Acyl-CoA 6-desaturase
- Very-long-chain 3-oxoacyl-CoA reductase-B
- Very-long-chain 3-oxoacyl-CoA reductase-A
- 20beta-hydroxysteroid dehydrogenase type 2
- stearoyl-CoA 9-desaturase | - IPR002076: ELO family (family) [14-260]
- IPR030457: ELO family, conserved site (conserved_site) [135-143]
- IPR033675: Elongation of very long chain fatty acids protein 6 (family) [1-266] | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0004312 (fatty acid synthase activity), GO:0009922 (fatty acid ... |
Q9VGK7 | Elongator complex protein 1 | Component of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at positi... | Drosophila melanogaster (Fruit fly) | 1,252 | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During asymmetric cell division of sensory organ precursor cells the elongator complex preferentially binds and stabilizes microtubules on the anterior side (pIIb daughter cell) of the spindle | MRNLKLRYCKELNAVAHPQHLLLQPELNGGASDIYFVVADNKIYAVQESGDVRLKVIADLPDIVGVEFLQLDNAICVASGAGEVILVDPQTGATSEGTFCDVGIESMAWSPNQEVVAFVTRTHNVVLMTSTFDVIAEQPLDAELDPDQQFVNVGWGKKETQFHGSEGKQAAKQKESDSTFIRDEQELNQDVSISWRGDGEFFVVSYVAAQLGRTFKVYDSEGKLNHTAEKSANLKDSVVWRPTGNWIAVPQQFPNKSTIALFEKNGLRHRELVLPFDLQEEPVVQLRWSEDSDILAIRTCAKEEQRVYLYTIGNYHWYLK... | [
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535",
"GO:1902494"
] | [] | [] | [
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535",
"GO:1902494"
] | AF-Q9VGK7-F1-model_v6.pdb | 7227.FBpp0307426 | [
"Q9VUR2",
"Q7JX95",
"Q9VFW4",
"Q8IQK9",
"Q7K4B3",
"Q9VIG1",
"Q9VQZ6",
"A1ZAW0",
"O46307",
"Q9VMQ7",
"Q7JWW5",
"Q9VEX3",
"O46079",
"Q9VGW6",
"Q9VGQ9",
"Q9VLJ8",
"Q7JVK6",
"Q9VNV9",
"Q24050"
] | [
"IPR056165",
"IPR056169",
"IPR006849",
"IPR056166",
"IPR015943",
"IPR056164",
"IPR056167"
] | {"IPR015943": [31, 315], "IPR006849": [1, 1251], "IPR056164": [1, 338], "IPR056165": [373, 633], "IPR056167": [657, 853], "IPR056166": [860, 1018], "IPR056169": [1031, 1197]} | - Elongator complex protein 3
- Elongator complex protein 2
- Elongator complex protein 5
- Protein KTI12 homolog
- Elongator complex protein 4
- Tetraspanin 68C, isoform A
- EG:8D8.4 protein
- Diphthamide biosynthesis protein 3
- Elongator complex protein 6
- Translin | - IPR056165: ELP1, N-terminal second beta-propeller (domain) [373-633]
- IPR056169: ELP1, three-helical bundle (domain) [1031-1197]
- IPR006849: Elongator complex protein 1 (family) [1-1251]
- IPR056166: ELP1, TPR domain (domain) [860-1018]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_su... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0043621 (protein self-association)
Biological Process (BP): GO:0008150 (biological process), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0065007 (biological regulation), ... |
Q7K4B3 | Elongator complex protein 2 | Component of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at po... | Drosophila melanogaster (Fruit fly) | 794 | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During asymmetric cell division of sensory organ precursor cells the elongator complex preferentially binds and stabilizes microtubules on the anterior side (pIIb daughter cell) of the spindle | MQVENLHTSVACNRCTECADWGPNGWIAYGACNAIAIMDPKFQGNSAKVLFTLVEHTKRVNTVRWLDCDKLLSGGDDAIAILWELDETGTTKSFTLKGHTSGVNTVDGIRQQDGSWLLATAAADTTIKLWTFQDNNYVCFQTISLSDGFCFCLRLQLLPKSNQVLLAFSGDDETVSLWSEQVETAGEGDSLGRQFQRKHKLTGHEDWVRGLDFVVDGEDLLLASGSQDNFIRLWRIAPRSKEQMQENRVDLHQLSHNDDEIKVEEKILQLGKEAWYAVSLESVLYGHEGWIYGVHWHKTPDQELRLLSASIDKTVIIWAP... | [
"GO:0000226",
"GO:0000278",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007051",
"GO:0007052",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022402",
"GO:0061867",
"GO:0071840",
"GO:1902850",
"GO:1903047",
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535"... | [
"GO:0000226",
"GO:0000278",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007051",
"GO:0007052",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022402",
"GO:0061867",
"GO:0071840",
"GO:1902850",
"GO:1903047"
] | [] | [
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535",
"GO:1902494"
] | AF-Q7K4B3-F1-model_v6.pdb | 7227.FBpp0087307 | [
"O46079",
"Q8I937",
"Q9VMQ7",
"Q9VFV8",
"Q9V732",
"Q9VGQ9",
"Q9VGK7",
"Q24050",
"Q9VE98",
"Q9V649",
"Q9VQZ6",
"Q9VPP3",
"Q8IQK9",
"Q9VFW4"
] | [
"IPR037289",
"IPR036322",
"IPR015943",
"IPR001680",
"IPR019775"
] | {"IPR015943": [4, 794], "IPR036322": [6, 792], "IPR037289": [1, 793], "IPR019775": [71, 85], "IPR001680": [46, 790]} | - Elongator complex protein 1
- Elongator complex protein 3
- Elongator complex protein 5
- Elongator complex protein 4
- Tetraspanin 68C, isoform A
- Protein KTI12 homolog
- Ribosome biogenesis regulatory protein
- DNA-directed RNA polymerase I subunit RPA1
- DNA-directed RNA polymerase III subunit RPC2
- LD47749p | - IPR037289: Elongator complex protein 2 (family) [1-793]
- IPR036322: WD40-repeat-containing domain superfamily (homologous_superfamily) [6-792]
- IPR015943: WD40/YVTN repeat-like-containing domain superfamily (homologous_superfamily) [4-794]
- IPR001680: WD40 repeat (repeat) [46-790]
- IPR019775: WD40 repeat, conserv... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding), GO:0019899 (enzyme binding), GO:0019900 (kinase binding), GO:0019901 (protein kinase binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological reg... |
Q1ZXC6 | Elongator complex protein 3 | Catalytic tRNA acetyltransferase subunit of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5- methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine) (By similarity). In the elongator complex, acts as a tRNA uridin... | Dictyostelium discoideum (Social amoeba) | 559 | null | MSLMNDPRPVSKKAGAKPVYGKNTPQFTKTVGEIVNALINAYKEGKKVNLLKIKTELAAKNSLSDQPKSVDIISAIPESYKNTLLPLLKAKPVRTASGIAVVAVMCKPHRCPHLAMTGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRAIRARYNPFLQTRHRIDQLKRLGHNVEKVEFIIMGGTFMSLPSDYRDYFIRNLHDALSGHTSNNVAEAVKYSEQSNVKCVGITIETRPDHCLKLHLSNMLTYGCTRLEIGVQSVFEDIARDTNRGHTVRAVLESFQLAKDSGFKVVAHMMPDLPNMGMERDIYGFMEFFENP... | [
"GO:0003674",
"GO:0003824",
"GO:0016407",
"GO:0016740",
"GO:0016746",
"GO:0016747",
"GO:0106261",
"GO:0140098",
"GO:0140101",
"GO:0140640",
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535",
"GO:1902494"
] | [] | [
"GO:0003674",
"GO:0003824",
"GO:0016407",
"GO:0016740",
"GO:0016746",
"GO:0016747",
"GO:0106261",
"GO:0140098",
"GO:0140101",
"GO:0140640"
] | [
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535",
"GO:1902494"
] | AF-Q1ZXC6-F1-model_v6.pdb | 44689.Q1ZXC6 | [
"Q86H29",
"Q54XS0",
"Q54CP4",
"Q9GPT6",
"Q54RL9",
"Q55FS0",
"Q55EX7",
"Q7KWL8",
"Q54Y82",
"Q86H45",
"Q54Q66"
] | [
"IPR000182",
"IPR058240",
"IPR056591",
"IPR007197",
"IPR032432",
"IPR034687",
"IPR039661",
"IPR016181",
"IPR006638"
] | {"IPR058240": [131, 370], "IPR016181": [367, 554], "IPR039661": [21, 558], "IPR034687": [24, 558], "IPR056591": [27, 96], "IPR007197": [47, 558], "IPR006638": [101, 363], "IPR032432": [325, 404], "IPR000182": [408, 559]} | - Elongator complex protein 1
- Elongator complex protein 4
- Elongator complex protein 2
- Cytoplasmic tRNA 2-thiolation protein 2
- Protein KTI12 homolog
- Cytoplasmic tRNA 2-thiolation protein 1
- Elongator complex protein 6
- Diphthamide biosynthesis protein 3
- DNA replication licensing factor mcm5
- Adenylyltrans... | - IPR000182: GNAT domain (domain) [408-559]
- IPR058240: Radical SAM superfamily (homologous_superfamily) [131-370]
- IPR056591: ELP3-like, N-terminal domain (domain) [27-96]
- IPR007197: Radical SAM (domain) [47-558]
- IPR032432: Radical SAM, C-terminal extension (domain) [325-404]
- IPR034687: Elongator complex prote... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016740 (transferase activity), GO:0016746 (acyltransferase activity), GO:0016747 (acyltransferase activity, transferring groups other than amino-acyl groups), GO:0016407 (acetyltransferase activity)
Biological Process (BP): G... |
Q9VMQ7 | Elongator complex protein 4 | Component of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at po... | Drosophila melanogaster (Fruit fly) | 437 | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During asymmetric cell division of sensory organ precursor cells the elongator complex preferentially binds and stabilizes microtubules on the anterior side (pIIb daughter cell) of the spindle | MTSFRKRTVQKPIRGTRTSPHTAQVITSSGNPYLDVVIGGGLPMGSICLIEEDRFMTHAKVLAKYFLAEGVISKQEIFLGSLDDIPAEMLRRLPRPLTDQESMEQSEVQALGDAGAENGLRIAWRYNDLPLVNSEHATAKIGHHFNLMEQMDSMMLYNVKTTLWDDSPKHLDIVIDEEFSKSSSPTTPSLEQQPVEDAPPIPGTETAPQEKMPAQEEENSANNNNNNNNNSSSVTSSTKTGSQDSPLQVFHNPRYKGLLNDIQQLLRNESFVAGTKNNLCRVCLTSLGSPLWYDEHFGEDLIKFLTLLMASVRNCNSVCL... | [
"GO:0000226",
"GO:0000278",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007051",
"GO:0007052",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022402",
"GO:0061867",
"GO:0071840",
"GO:1902850",
"GO:1903047",
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535"... | [
"GO:0000226",
"GO:0000278",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007051",
"GO:0007052",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022402",
"GO:0061867",
"GO:0071840",
"GO:1902850",
"GO:1903047"
] | [] | [
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535",
"GO:1902494"
] | AF-Q9VMQ7-F1-model_v6.pdb | 7227.FBpp0078729 | [
"Q9VFW4",
"Q9VQZ6",
"Q24050",
"Q9VGK7",
"Q9VLJ8",
"Q9VGQ9",
"Q7K4B3"
] | [
"IPR027417",
"IPR008728"
] | {"IPR027417": [8, 415], "IPR008728": [1, 437]} | - Elongator complex protein 3
- Elongator complex protein 5
- Elongator complex protein 1
- Elongator complex protein 2
- Elongator complex protein 6
- Diphthamide biosynthesis protein 3
- Adenylyltransferase and sulfurtransferase MOCS3 | - IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [8-415]
- IPR008728: Elongator complex protein 4 (family) [1-437] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0065007 (biological regulation), GO:0050789 (regulation of biological process), GO:0009987 (cellular process), GO:0043... |
Q24050 | Elongator complex protein 5 | Component of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes the formation of carboxymethyluridine in the wobble base at po... | Drosophila melanogaster (Fruit fly) | 262 | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During asymmetric cell division of sensory organ precursor cells the elongator complex preferentially binds and stabilizes microtubules on the anterior side (pIIb daughter cell) of the spindle | MLSNLVVTKQKVVLVIDELNRERIAPKFIGSLLHEQGQGADTIKALPTGVSLKHVATFEALIDKYANNNTGSTTDSNSTGFNVILPTLADLLCYQTPAFIFGFLNRLRRSDNVRRVFLWASPQHLQDPHADYILAGCEYLAELVLRLESDKLLSLISRKPGGGVSNRRYSCEVSKTQFKVTPLDGGLPAGASPKQPSPEAEQTTEPASSTFKIELDEDEVLARNALTLPYERTSEPSEGNIIYTPDADDDFDEEDPDEDLCI | [
"GO:0000226",
"GO:0000278",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007051",
"GO:0007052",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022402",
"GO:0061867",
"GO:0071840",
"GO:1902850",
"GO:1903047",
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535"... | [
"GO:0000226",
"GO:0000278",
"GO:0006996",
"GO:0007010",
"GO:0007017",
"GO:0007049",
"GO:0007051",
"GO:0007052",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0022402",
"GO:0061867",
"GO:0071840",
"GO:1902850",
"GO:1903047"
] | [] | [
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535",
"GO:1902494"
] | AF-Q24050-F1-model_v6.pdb | 7227.FBpp0304910 | [
"Q9VQZ6",
"O46079",
"Q7JWW5",
"Q9W397",
"Q9VMQ7",
"Q9VLJ8",
"Q9VGK7",
"Q8IQK9",
"Q9VFW4",
"Q7K4B3"
] | [
"IPR019519"
] | {"IPR019519": [55, 262]} | - Elongator complex protein 1
- Elongator complex protein 3
- Elongator complex protein 2
- Elongator complex protein 4
- Elongator complex protein 6
- Tetraspanin 68C, isoform A
- RE67794p
- Protein KTI12 homolog
- Cytoplasmic tRNA 2-thiolation protein 1
- Adenylyltransferase and sulfurtransferase MOCS3 | - IPR019519: Elongator complex protein 5 (family) [55-262] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic process), GO:0009987 (cellular process), GO:0032501 (multicellular organismal process), GO:0044237 (cellular metabolic process), GO... |
Q9VFW4 | Elongator complex protein 6 | Component of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at positi... | Drosophila melanogaster (Fruit fly) | 251 | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle. Note=Concentrates in the nucleus upon insulin stimulation. During asymmetric cell division of sensory organ precursor cells the elongator complex preferentially binds and stabilizes microtubules on the anterior side (pIIb daughter cell) of the spindle | MATSVLLACGLNEQKLPGFVHISEESNVDASFLISCVLGQRLRISNAGTLLVCLQHHYQHYFNAGMRLGYNTNIFQGKTLGVIDVLSDMAGEGLASKWLTNTEGQTLTDQLVEDIRAQVERNYASRNSYTVLIDNLSILFNLGASKLQVQQFCQDLAALGKEREKLTVITKLSNSDIYQLTDNNVAKLGQVRIQVLRLKSGVFREVDGKLLIERVLDEGNYACEETRKEVLYKVNDRNVKVFAPGEIGVKV | [
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535",
"GO:1902494"
] | [] | [] | [
"GO:0005575",
"GO:0032991",
"GO:0033588",
"GO:0140535",
"GO:1902494"
] | AF-Q9VFW4-F1-model_v6.pdb | 7227.FBpp0292357 | [
"Q24050",
"Q9VGK7",
"Q7K4B3",
"Q9VMQ7",
"Q8IQK9",
"Q9W1I1",
"Q9VQZ6"
] | [
"IPR018627",
"IPR027417"
] | {"IPR027417": [3, 243], "IPR018627": [6, 246]} | - Elongator complex protein 5
- Elongator complex protein 4
- Elongator complex protein 3
- Elongator complex protein 1
- TAR DNA-binding protein 43
- Tetraspanin 68C, isoform A
- Elongator complex protein 2 | - IPR018627: Elongator complex protein 6 (family) [6-246]
- IPR027417: P-loop containing nucleoside triphosphate hydrolase (homologous_superfamily) [3-243] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0044877 (protein-containing complex binding), GO:0005515 (protein binding), GO:0005102 (signaling receptor binding), GO:0005158 (insulin receptor binding)
Biological Process (BP): GO:0008150 (biological process), GO:0008152 (metabolic pr... |
Q5AJ82 | Actin cytoskeleton-regulatory complex protein END3 | Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane prot... | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) | 395 | Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches | MPRLEESEIKKYWQIFQSLKPQNNKLTGDQLSSILKNSQLPQQQLSAIWELSDIDNDGKLDFEEFCIIMRLIFDVINGKLPNVPQELPSWLIPASKSAIIQANKAVNQGNNNFGDIDDDEDDKLSNDFDWYISPTDKSIYEKIYDSKCDSFGRIKYSSLNELYNGLTNVPSSEISSAWNLINPKSFETIDKDQTLVFLHILNQRENGKRIPRGVPASLRATFSKEVPNYDLSAQAKPSISATTETGKKSFAENYLNKIGGGVGASSTINNGRNEKGTDFSATQGTDWEEVRLRRELQDLERLLDKVQNDTKNQKDNSNNN... | [
"GO:0006810",
"GO:0006897",
"GO:0006996",
"GO:0007010",
"GO:0007015",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0016192",
"GO:0030029",
"GO:0030036",
"GO:0030447",
"GO:0040007",
"GO:0051179",
"GO:0051234",
"GO:0071840",
"GO:0097435",
"GO:0098657"
] | [
"GO:0006810",
"GO:0006897",
"GO:0006996",
"GO:0007010",
"GO:0007015",
"GO:0008150",
"GO:0009987",
"GO:0016043",
"GO:0016192",
"GO:0030029",
"GO:0030036",
"GO:0030447",
"GO:0040007",
"GO:0051179",
"GO:0051234",
"GO:0071840",
"GO:0097435",
"GO:0098657"
] | [] | [] | AF-Q5AJ82-F1-model_v6.pdb | 237561.Q5AJ82 | [
"A0A1D8PU03",
"Q5A961",
"A0A1D8PFR4",
"A0A1D8PRF5",
"Q5ALV2",
"Q5AHB1",
"Q5AMQ2",
"A0A1D8PPS9",
"A0A1D8PGB7"
] | [
"IPR000261",
"IPR011992",
"IPR025604",
"IPR018247",
"IPR002048"
] | {"IPR011992": [4, 222], "IPR025604": [274, 388], "IPR000261": [1, 225], "IPR002048": [40, 75], "IPR018247": [53, 65]} | - Actin cytoskeleton-regulatory complex protein PAN1
- Actin cytoskeleton-regulatory complex protein SLA1
- Sla2p
- Clathrin light chain
- Actin
- Clathrin heavy chain
- Actin-binding protein
- Actin-regulating kinase PRK1
- Epsin | - IPR000261: EH domain (domain) [1-225]
- IPR011992: EF-hand domain pair (homologous_superfamily) [4-222]
- IPR025604: Actin cytoskeleton-regulatory complex protein End3 (family) [274-388]
- IPR018247: EF-Hand 1, calcium-binding site (binding_site) [53-65]
- IPR002048: EF-hand domain (domain) [40-75] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0043167 (ion binding), GO:0005515 (protein binding), GO:0043169 (cation binding), GO:0046872 (metal ion binding), GO:0005509 (calcium ion binding)
Biological Process (BP): GO:0008150 (biological process), GO:0050896 (response to stimulus... |
P0A6C1 | Endonuclease 4 | Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin | Escherichia coli (strain K12) | 285 | null | MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | [] | [] | [
"GO:0005575",
"GO:0005622",
"GO:0005737",
"GO:0005829",
"GO:0110165"
] | AF-P0A6C1-F1-model_v6.pdb | 511145.b2159 | [
"P78213",
"Q2M8T5",
"P04395",
"Q2M9N2",
"Q2M6P2",
"Q2M6P6",
"Q2M8K5",
"P09030",
"Q60139",
"Q53442",
"Q2MAR9",
"Q2M8G1",
"P20625",
"P12295",
"Q2M7U9"
] | [
"IPR013022",
"IPR001719",
"IPR018246",
"IPR036237"
] | {"IPR036237": [1, 277], "IPR001719": [1, 282], "IPR013022": [20, 277], "IPR018246": [69, 231]} | - Exodeoxyribonuclease III
- Endonuclease III
- Endonuclease III
- Uncharacterized sugar kinase YeiI
- Formamidopyrimidine-DNA glycosylase
- Superoxide dismutase [Mn]
- UvrABC system protein A
- Uracil-DNA glycosylase
- Adenine DNA glycosylase
- Endonuclease V | - IPR013022: Xylose isomerase-like, TIM barrel domain (domain) [20-277]
- IPR001719: AP endonuclease 2 (family) [1-282]
- IPR018246: AP endonuclease 2, zinc binding site (binding_site) [69-231]
- IPR036237: Xylose isomerase-like superfamily (homologous_superfamily) [1-277] | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0003824 (catalytic activity), GO:0016787 (hydrolase activity), GO:0140640 (catalytic activity, acting on a nucleic acid), GO:0043167 (ion binding), GO:0016788 (hydrolase activity, acting on ester bonds), GO:0043169 (cation binding), GO:0... |
P13929 | Beta-enolase | Glycolytic enzyme that catalyzes the conversion of 2- phosphoglycerate to phosphoenolpyruvate. Appears to have a function in striated muscle development and regeneration | Homo sapiens (Human) | 434 | Cytoplasm. Note=Localized to the Z line. Some colocalization with CKM at M-band (By similarity) | MAMQKIFAREILDSRGNPTVEVDLHTAKGRFRAAVPSGASTGIYEALELRDGDKGRYLGKGVLKAVENINNTLGPALLQKKLSVVDQEKVDKFMIELDGTENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMRIGAEVYHHLKGVIKAKYGKDATNVGDEGGFAPNILENNEALELLKTAIQAAGYPDKVVIGMDVAASEFYRNGKYDLDFKSPDDPARHITGEKLGELYKSFIKNYPVVSIEDPFDQDDWATWTSFLSGVNIQIVGDDL... | [
"GO:0005975",
"GO:0005996",
"GO:0006006",
"GO:0006007",
"GO:0006082",
"GO:0006090",
"GO:0006091",
"GO:0006094",
"GO:0006096",
"GO:0006139",
"GO:0006163",
"GO:0006195",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009058",
"GO:0009060"... | [
"GO:0005975",
"GO:0005996",
"GO:0006006",
"GO:0006007",
"GO:0006082",
"GO:0006090",
"GO:0006091",
"GO:0006094",
"GO:0006096",
"GO:0006139",
"GO:0006163",
"GO:0006195",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009058",
"GO:0009060"... | [] | [] | AF-P13929-F1-model_v6.pdb | 9606.ENSP00000324105 | [
"Q96AG5",
"Q5VSR8",
"Q9NV31",
"Q9BR91",
"Q96AS8",
"Q9HCU6",
"Q9NTY4",
"Q96PQ2",
"Q8TC75",
"Q8TCY3",
"Q5T7D6",
"Q96G82",
"Q969Z9",
"P30613",
"Q53X65",
"Q8NI26",
"Q9H0K0",
"Q9H0I9",
"Q8WTY2",
"Q9Y622",
"Q96QL9",
"Q9BVX0",
"Q9UCN2",
"Q9Y315",
"Q6P0L5",
"J3KNX1",
"Q8N... | [
"IPR029017",
"IPR020811",
"IPR000941",
"IPR036849",
"IPR020810",
"IPR020809"
] | {"IPR029017": [1, 138], "IPR036849": [128, 434], "IPR000941": [1, 430], "IPR020811": [3, 134], "IPR020810": [142, 431], "IPR020809": [340, 353]} | - Pyruvate kinase PKM
- Phosphoglycerate mutase 2
- Phosphoglycerate mutase 1
- Probable phosphoglycerate mutase 4
- Pyruvate kinase PKLR
- Glucose-6-phosphate isomerase
- Bisphosphoglycerate mutase
- Fructose-bisphosphate aldolase A
- Triosephosphate isomerase
- Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | - IPR029017: Enolase-like, N-terminal (homologous_superfamily) [1-138]
- IPR020811: Enolase, N-terminal (domain) [3-134]
- IPR000941: Enolase (family) [1-430]
- IPR036849: Enolase-like, C-terminal domain superfamily (homologous_superfamily) [128-434]
- IPR020810: Enolase, C-terminal TIM barrel domain (domain) [142-431]... | Molecular Function (MF): GO:0003674 (molecular function), GO:0003824 (catalytic activity), GO:0016829 (lyase activity), GO:0016835 (carbon-oxygen lyase activity), GO:0016836 (hydro-lyase activity), GO:0004634 (phosphopyruvate hydratase activity)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (posi... |
P09104 | Gamma-enolase | Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium- dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity) | Homo sapiens (Human) | 434 | Cytoplasm. Cell membrane. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form | MSIEKIWAREILDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAERELPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKIVIGMDVAASEFYRDGKYDLDFKSPTDPSRYITGDQLGALYQDFVRDYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDL... | [
"GO:0005975",
"GO:0005996",
"GO:0006006",
"GO:0006007",
"GO:0006082",
"GO:0006090",
"GO:0006091",
"GO:0006094",
"GO:0006096",
"GO:0006139",
"GO:0006163",
"GO:0006195",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009058",
"GO:0009060"... | [
"GO:0005975",
"GO:0005996",
"GO:0006006",
"GO:0006007",
"GO:0006082",
"GO:0006090",
"GO:0006091",
"GO:0006094",
"GO:0006096",
"GO:0006139",
"GO:0006163",
"GO:0006195",
"GO:0006753",
"GO:0006793",
"GO:0006796",
"GO:0008150",
"GO:0008152",
"GO:0009056",
"GO:0009058",
"GO:0009060"... | [] | [] | AF-P09104-F1-model_v6.pdb | 9606.ENSP00000437402 | [
"Q9Y315",
"Q9UJD2",
"J3KPS3",
"Q9H107",
"P15259",
"Q71UM0",
"P02771",
"Q9BVZ0",
"P07738",
"Q9BTV8",
"Q9UJZ0",
"Q9UHE6",
"Q96QK4",
"Q9BV62",
"Q8WZ45",
"P40926",
"P01298",
"Q9BWC0",
"Q6P2F7",
"Q6ZTT1",
"Q9UNW1",
"Q9UFD0",
"Q9Y3R7",
"P35900",
"Q96HH3",
"R4GMU1",
"Q9P... | [
"IPR029017",
"IPR020811",
"IPR000941",
"IPR036849",
"IPR020810",
"IPR020809"
] | {"IPR029017": [1, 138], "IPR036849": [128, 434], "IPR000941": [1, 430], "IPR020811": [3, 134], "IPR020810": [142, 431], "IPR020809": [340, 353]} | - Phosphoglycerate mutase 1
- Pyruvate kinase PKM
- Probable phosphoglycerate mutase 4
- Pyruvate kinase PKLR
- Glucose-6-phosphate isomerase
- Phosphoglycerate mutase 2
- Bisphosphoglycerate mutase
- Phosphoglycerate kinase 1
- Triosephosphate isomerase
- Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | - IPR029017: Enolase-like, N-terminal (homologous_superfamily) [1-138]
- IPR020811: Enolase, N-terminal (domain) [3-134]
- IPR000941: Enolase (family) [1-430]
- IPR036849: Enolase-like, C-terminal domain superfamily (homologous_superfamily) [128-434]
- IPR020810: Enolase, C-terminal TIM barrel domain (domain) [142-431]... | Molecular Function (MF): GO:0003674 (molecular function), GO:0005488 (binding), GO:0005515 (protein binding)
Biological Process (BP): GO:0008150 (biological process), GO:0048518 (positive regulation of biological process), GO:0050789 (regulation of biological process), GO:0065007 (biological regulation), GO:0050896 (re... |
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