Update Policy — Ethno-API Dataset
Release Schedule
The full dataset is refreshed annually. Next scheduled update: Q1 2027.
Enrichment Sources
- PubMed via NCBI E-utilities (esearch)
- ClinicalTrials.gov API v2
- ChEMBL REST API (with PubChem InChIKey fallback)
- PatentsView REST API (USPTO)
- PubChem PUG REST API (CID + Canonical SMILES)
Versioning
Current version: v2.4.0 (April 2026) All versions are tagged in this repository.
v2.4.0 Changelog
- Added partner_cid column (cross-matched PubChem CID from COCONUT/FooDB)
- Added inchi_key column (InChI key for structural identification)
- Added iupac_verified column (PubChem CID verified via IUPAC name resolution)
- Added partner_match_method column (cross-match methodology transparency)
- Null-CID reduced to 17,616 (-8% vs v2.3.1)
- Schema expanded from 12 to 16 columns
- DOI: 10.5281/zenodo.19660107
v2.3.1 Changelog
- Added compound_type column (5 categories: discrete_phytochemical, substance_class, complex_mixture, inorganic_element, generic_ambiguous)
- Added patent_count_method column (query methodology transparency)
- RESIN/RESINS CID correction (CID 133110026 was alpha-Copaene, set to NULL)
- Forensic audit corrections for inorganic/generic compounds
- PubChem CID/SMILES coverage: 75.4% (unchanged from v2.3)
- DOI: 10.5281/zenodo.19660107
v2.3 Changelog
- PubChem CID/SMILES coverage: 75.4% (up from 71.8% in v2.2)
- CTS worker resolved 997 additional compounds via PubChem PUG-REST name-to-CID
- 2,741 records improved in correction pass
- DOI: 10.5281/zenodo.19660107
Buyer Notifications
All dataset buyers receive email notification when a new version is available. Buyers of v2.0, v2.1, v2.2, v2.3, or v2.3.1 receive the v2.4.0 update free of charge.
Breaking Changes
Schema changes are announced minimum 30 days in advance via GitHub Discussions.
Known Limitations
See METHODOLOGY.md for full documentation of data quality limitations and noise exclusions.