| # Update Policy — Ethno-API Dataset |
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| ## Release Schedule |
| The full dataset is refreshed annually. |
| Next scheduled update: Q1 2027. |
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| ## Enrichment Sources |
| - PubMed via NCBI E-utilities (esearch) |
| - ClinicalTrials.gov API v2 |
| - ChEMBL REST API (with PubChem InChIKey fallback) |
| - PatentsView REST API (USPTO) |
| - PubChem PUG REST API (CID + Canonical SMILES) |
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| ## Versioning |
| Current version: v2.4.0 (April 2026) |
| All versions are tagged in this repository. |
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| ## v2.4.0 Changelog |
| - Added partner_cid column (cross-matched PubChem CID from COCONUT/FooDB) |
| - Added inchi_key column (InChI key for structural identification) |
| - Added iupac_verified column (PubChem CID verified via IUPAC name resolution) |
| - Added partner_match_method column (cross-match methodology transparency) |
| - Null-CID reduced to 17,616 (-8% vs v2.3.1) |
| - Schema expanded from 12 to 16 columns |
| - DOI: 10.5281/zenodo.19660107 |
| |
| ## v2.3.1 Changelog |
| - Added compound_type column (5 categories: discrete_phytochemical, substance_class, complex_mixture, inorganic_element, generic_ambiguous) |
| - Added patent_count_method column (query methodology transparency) |
| - RESIN/RESINS CID correction (CID 133110026 was alpha-Copaene, set to NULL) |
| - Forensic audit corrections for inorganic/generic compounds |
| - PubChem CID/SMILES coverage: 75.4% (unchanged from v2.3) |
| - DOI: 10.5281/zenodo.19660107 |
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| ## v2.3 Changelog |
| - PubChem CID/SMILES coverage: 75.4% (up from 71.8% in v2.2) |
| - CTS worker resolved 997 additional compounds via PubChem PUG-REST name-to-CID |
| - 2,741 records improved in correction pass |
| - DOI: 10.5281/zenodo.19660107 |
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| ## Buyer Notifications |
| All dataset buyers receive email notification when a new version is available. |
| Buyers of v2.0, v2.1, v2.2, v2.3, or v2.3.1 receive the v2.4.0 update free of charge. |
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| ## Breaking Changes |
| Schema changes are announced minimum 30 days in advance via GitHub Discussions. |
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| ## Known Limitations |
| See METHODOLOGY.md for full documentation of data quality limitations and noise exclusions. |
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