accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
B7HVW2 | SYM_BACC7 | Methionyl-tRNA synthetase | Bacillus cereus group | <M><S><I><F><I><G><G><A><W><P><Y><A><N><G><S><L><H><L><G><H><I><A><S><L><L><P><G><D><I><L><A><R><Y><Y><R><A><K><G><E><N><V><L><Y><V><S><G><S><D><C><N><G><T><P><I><A><I><R><A><K><Q><E><G><V><T><A><K><D><I><A><D><Q><Y><H><E><E><F><E><R><C><F><R><S><L><G><F><T><Y><D><C><Y><T><R><T><D><S><E><H><H><H><E><T><V><Q><N><V><F><L... | Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.<BOP> | B7HVW2 |
Q6G078 | PANB_BARQU | Ketopantoate hydroxymethyltransferase | Bartonella | <M><S><I><H><Q><T><I><K><R><I><T><A><A><E><I><R><S><R><K><G><Q><E><P><I><V><S><L><T><A><Y><Q><A><Y><S><A><R><I><A><D><P><Y><C><D><F><L><L><V><G><D><S><V><G><M><V><V><H><G><F><E><T><T><L><P><V><S><L><D><M><M><I><L><H><G><Q><A><V><M><R><G><A><K><K><A><L><V><V><I><D><M><P><F><G><S><Y><E><E><S><P><E><Q><A><F><S><N><A><S><R... | Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.<BOP> | Q6G078 |
Q94WW9 | CYB_CTEMU | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Ctenomys | <M><T><N><T><R><K><S><H><P><L><I><K><I><M><N><H><S><F><I><D><L><P><T><P><S><N><I><S><A><W><W><N><F><G><S><L><L><G><V><C><L><G><L><Q><I><L><T><G><L><F><L><A><M><H><Y><T><A><D><T><T><T><A><F><S><S><V><T><H><I><C><R><D><V><N><Y><G><W><L><I><R><Y><M><H><A><N><G><A><S><M><F><F><I><F><L><Y><F><H><I><G><R><G><I><Y><Y><G><S><Y... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q94WW9 |
Q9NDH7 | GLY2_CAEEL | N-acetylglucosaminyltransferase gly-2 | Caenorhabditis | <M><R><R><R><H><R><C><V><A><L><L><F><I><F><S><A><F><I><T><P><L><G><F><F><Y><Y><T><I><S><N><E><S><K><R><Y><S><E><E><S><E><K><N><Y><G><Y><Q><T><L><E><F><T><E><S><P><E><E><I><S><V><D><F><D><K><Y><S><Q><S><E><C><S><R><F><P><S><N><V><E><I><E><Y><P><E><C><L><N><K><M><K><W><I><K><N><G><W><K><T><H><H><C><Y><I><E><N><H><I><D><G... | Catalyzes the addition of N-acetylglucosamine (GlcNAc) in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides.<BOP> | Q9NDH7 |
Q5F9L0 | RLME_NEIG1 | rRNA (uridine-2'-O-)-methyltransferase | Neisseria | <M><A><V><R><S><K><S><S><K><A><W><L><H><E><H><I><N><D><Q><Y><V><H><M><A><Q><K><D><G><Y><R><A><R><A><A><Y><K><L><L><E><I><N><E><K><D><K><I><I><K><P><G><T><V><L><A><D><L><G><S><A><P><G><S><W><S><Q><V><A><A><K><L><T><G><T><S><G><A><V><F><A><L><D><I><L><P><M><E><A><I><G><G><V><S><F><I><Q><G><D><F><R><E><N><D><V><L><A><Q><F... | Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.<BOP> | Q5F9L0 |
P50976 | PTLCB_STRMU | Lactose-specific phosphotransferase enzyme IIB component | Streptococcus | <M><N><T><L><I><A><Q><I><E><K><G><K><P><F><F><E><K><I><S><R><N><I><Y><L><R><A><I><R><D><G><F><I><S><A><M><P><V><I><L><F><S><S><I><F><L><L><I><A><Y><V><P><N><I><F><G><F><T><W><P><K><G><I><E><N><M><L><M><T><P><Y><N><Y><T><M><G><I><I><G><F><L><V><A><G><T><T><A><K><S><L><T><D><S><M><N><R><Q><L><E><K><T><N><Q><I><N><F><I><S... | The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LacEF PTS system is involved in lactose transport.<BOP> | P50976 |
Q16877 | F264_HUMAN | Fructose-2,6-bisphosphatase | Homo | <M><A><S><P><R><E><L><T><Q><N><P><L><K><K><I><W><M><P><Y><S><N><G><R><P><A><L><H><A><C><Q><R><G><V><C><M><T><N><C><P><T><L><I><V><M><V><G><L><P><A><R><G><K><T><Y><I><S><K><K><L><T><R><Y><L><N><W><I><G><V><P><T><R><E><F><N><V><G><Q><Y><R><R><D><V><V><K><T><Y><K><S><F><E><F><F><L><P><D><N><E><E><G><L><K><I><R><K><Q><C><A... | Synthesis and degradation of fructose 2,6-bisphosphate.<BOP> | Q16877 |
Q67N40 | LIPM_SYMTH | Octanoyl-[acyl-carrier-protein]:[GcvH] N-octanoyltransferase | Symbiobacterium | <M><E><T><N><W><R><L><L><D><T><G><H><R><P><G><P><E><N><M><A><I><D><E><A><I><A><M><A><H><G><R><G><E><V><P><P><T><L><R><F><Y><G><W><N><P><P><A><V><S><I><G><Y><F><Q><S><M><L><G><E><V><D><L><D><A><V><R><A><G><G><Y><G><Y><V><R><R><P><T><G><G><R><L><I><F><H><H><M><E><L><T><Y><S><V><V><I><R><E><E><L><L><P><G><G><V><I><E><T><Y... | Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.<BOP> | Q67N40 |
P48946 | RS18_SYNY3 | 30S ribosomal protein S18 | unclassified Synechocystis | <M><N><Y><Y><R><K><R><L><S><P><L><P><P><N><Q><P><I><D><Y><K><D><T><E><L><L><R><K><F><I><T><E><R><G><K><I><L><P><R><R><I><T><G><L><T><A><K><Q><Q><R><D><L><T><T><A><V><K><R><S><R><L><V><A><L><L><P><F><V><N><K><E><I> | Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.<BOP> | P48946 |
A5GE10 | ISPH_GEOUR | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | Geotalea | <M><K><V><I><L><A><K><Q><A><G><F><C><F><G><V><K><R><A><T><Q><M><A><F><E><A><A><D><K><G><G><K><T><Y><T><L><G><P><I><I><H><S><P><Q><V><V><Q><K><L><E><E><M><G><V><K><A><L><K><D><I><S><G><M><D><D><G><T><I><I><I><R><S><H><G><V><A><S><G><E><L><E><E><A><V><R><K><E><L><E><I><V><D><A><T><C><P><F><V><K><K><A><Q><E><H><V><E><S><L... | Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.<BOP> | A5GE10 |
Q5ATH1 | APDC_EMENI | Aspyridones biosynthesis protein C | Aspergillus subgen. Nidulantes | <M><I><P><P><K><Q><Q><T><A><L><K><I><T><P><E><G><R><I><A><A><V><S><S><P><L><P><S><L><Q><D><N><E><L><L><V><C><V><K><S><I><A><L><N><P><F><D><A><K><S><A><E><M><S><P><T><I><G><A><T><L><G><C><D><F><A><G><K><I><V><A><T><G><S><N><A><N><D><F><N><F><S><I><G><D><R><V><C><G><C><V><F><G><N><N><P><N><R><L><D><N><G><A><F><A><E><Y><V... | Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of aspyridones . The polyketide-amino acid backbone preaspyridone A is first assembled by the PKS-NRPS hybrid apdA . The assembly of preaspyridone A is initiated by loading of malonyl-CoA onto apdA, followed by decarboxylation to yield the a... | Q5ATH1 |
A5EWA3 | CSRA_DICNV | Carbon storage regulator | Dichelobacter | <M><L><I><L><T><R><R><V><G><E><T><I><I><I><D><D><Q><I><K><V><T><V><L><A><V><K><G><N><Q><V><R><L><G><V><Q><A><P><D><E><I><A><I><H><R><E><E><I><Y><H><R><L><M><N><G><V><G><D><D><A><E><M><E><K><K> | A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding... | A5EWA3 |
Q7NZD1 | UBIB_CHRVO | Ubiquinone biosynthesis protein UbiB | Chromobacterium | <M><S><I><S><R><S><L><K><I><V><A><T><L><Y><R><Y><G><L><D><D><F><L><E><G><H><S><R><L><A><F><L><H><K><L><F><G><L><C><P><V><R><R><D><T><S><A><P><L><P><Q><R><V><R><L><A><L><E><S><L><G><P><I><F><V><K><F><G><Q><V><L><S><T><R><R><D><L><L><P><P><E><Y><A><D><E><L><A><L><L><Q><D><R><V><P><P><F><D><G><D><I><A><R><Q><V><V><E><R><S... | Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.<BOP> | Q7NZD1 |
Q3IFW0 | GCSH_PSET1 | Glycine cleavage system H protein | Pseudoalteromonas | <M><S><N><I><P><S><E><L><K><Y><A><S><S><H><E><W><V><R><N><E><G><D><G><T><F><T><V><G><I><T><E><H><A><Q><E><L><L><G><D><M><V><F><V><E><L><P><E><V><G><D><E><V><D><A><G><E><E><C><A><V><A><E><S><V><K><A><A><S><D><I><Y><A><P><I><G><G><E><I><V><A><I><N><E><E><L><E><D><A><P><E><T><V><N><T><D><A><F><G><D><G><W><L><F><R><I><K><A... | The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.<BOP> | Q3IFW0 |
Q89AK7 | BIOC_BUCBP | Biotin synthesis protein BioC | Buchnera | <M><I><D><K><K><K><I><A><E><A><F><G><K><A><A><A><N><Y><D><N><F><S><V><I><Q><R><I><A><G><N><I><L><L><S><K><I><E><T><F><F><N><I><S><I><L><D><A><G><C><G><T><G><W><F><S><K><K><W><R><Q><L><G><N><T><V><T><A><L><D><F><S><K><N><M><L><L><T><A><K><N><T><N><S><A><D><Y><Y><L><H><A><D><M><E><Q><L><P><I><C><D><N><I><F><D><L><S><W><S... | Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.<BOP> | Q89AK7 |
P38710 | INM1_YEAST | Inositol-1(or 4)-monophosphatase 1 | Saccharomyces | <M><T><I><D><L><A><S><I><E><K><F><L><C><E><L><A><T><E><K><V><G><P><I><I><K><S><K><S><G><T><Q><K><D><Y><D><L><K><T><G><S><R><S><V><D><I><V><T><A><I><D><K><Q><V><E><K><L><I><W><E><S><V><K><T><Q><Y><P><T><F><K><F><I><G><E><E><S><Y><V><K><G><E><T><V><I><T><D><D><P><T><F><I><I><D><P><I><D><G><T><T><N><F><V><H><D><F><P><F><S... | Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides.<BOP> | P38710 |
Q9CDG1 | EFG_LACLA | Elongation factor G | Lactococcus | <M><A><R><E><F><S><L><A><N><T><R><N><I><G><I><M><A><H><V><D><A><G><K><T><T><T><T><E><R><V><L><Y><Y><T><G><K><I><H><K><I><G><E><T><H><E><G><A><S><Q><M><D><W><M><E><Q><E><Q><E><R><G><I><T><I><T><S><A><A><T><T><A><E><W><K><G><N><R><V><N><I><I><D><T><P><G><H><V><D><F><T><I><E><V><Q><R><S><L><R><V><L><D><G><A><V><T><V><L><D... | Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respective... | Q9CDG1 |
Q2NGG1 | THIM2_METST | 4-methyl-5-beta-hydroxyethylthiazole kinase 2 | Methanosphaera | <M><L><E><Q><C><S><K><N><I><E><K><L><R><N><K><C><P><L><T><H><C><I><T><N><Y><V><T><I><N><D><C><A><N><V><V><L><A><I><G><G><S><P><A><M><A><N><E><A><P><E><I><E><E><F><V><E><A><A><G><V><T><I><I><N><M><G><T><L><L><E><D><Q><I><E><P><M><Q><I><A><A><C><H><T><K><K><T><N><T><P><L><V><L><D><P><V><A><V><G><V><S><K><L><R><N><D><I><T... | Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP> | Q2NGG1 |
Q5F783 | PRMB_NEIG1 | N5-glutamine methyltransferase PrmB | Neisseria | <M><V><H><I><M><F><N><Q><A><A><Q><E><L><T><T><I><R><D><V><L><R><F><A><V><S><R><F><N><E><A><G><L><F><F><G><H><G><T><D><N><A><H><D><E><A><V><Y><L><I><L><H><T><L><N><L><P><L><D><M><L><A><P><Y><L><D><A><K><L><L><E><A><E><K><E><E><V><L><A><V><I><E><R><R><A><V><E><H><I><P><A><A><Y><L><T><H><Q><A><W><Q><G><E><F><D><F><Y><V><D... | Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.<BOP> | Q5F783 |
Q9TZI4 | GBAS1_CAEEL | G-protein alpha subunit activating protein gbas-1 | Caenorhabditis | <M><R><S><V><R><S><S><S><R><T><P><K><P><V><K><R><F><V><F><D><E><D><E><D><L><E><E><I><D><L><D><E><V><D><N><A><D><F><E><R><E><D><D><E><E><E><V><L><S><E><P><S><E><S><P><Y><T><S><T><P><K><S><S><K><R><V><N><K><T><R><G><T><K><D><F><F><K><K><D><E><S><L><Q><L><F><R><F><V><L><N><E><C><R><S><Q><K><P><G><R><V><G><R><V><A><K><K><R... | Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates G-protein alpha subunit goa-1.<BOP> | Q9TZI4 |
B8EBI6 | RL15_SHEB2 | 50S ribosomal protein L15 | Shewanella | <M><R><L><N><T><L><S><P><A><A><G><S><K><H><A><P><K><R><V><G><R><G><M><G><S><G><L><G><K><T><A><G><R><G><H><K><G><Q><K><S><R><S><G><G><G><V><R><P><G><F><E><G><G><Q><M><P><L><K><I><R><L><P><K><F><G><F><T><S><R><R><A><M><V><T><A><E><V><R><V><L><E><L><A><K><V><N><G><D><V><I><D><L><N><A><L><K><D><A><N><V><I><T><R><N><I><Q><F... | Binds to the 23S rRNA.<BOP> | B8EBI6 |
Q9HL07 | RL13_THEAC | 50S ribosomal protein L13 | Thermoplasma | <M><R><V><I><D><A><S><G><A><I><Y><G><R><L><S><A><Y><V><A><K><R><L><L><E><G><E><E><I><T><I><V><N><A><S><K><A><V><I><T><G><N><K><E><F><I><I><E><K><F><K><E><R><L><D><I><G><S><V><R><K><G><P><Y><Y><P><K><T><P><E><N><I><L><R><R><S><I><G><D><M><L><P><K><K><I><T><K><G><K><E><A><L><A><R><C><R><V><Y><R><N><T><P><P><D><I><E><K><E... | This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.<BOP> | Q9HL07 |
P62214 | RECA_DESVH | Recombinase A | Desulfovibrio | <M><A><K><K><P><S><L><S><P><E><E><M><R><R><E><A><L><E><T><A><L><S><T><I><E><R><K><Y><G><L><G><A><V><M><K><L><S><D><E><A><H><V><A><I><P><V><I><P><T><G><S><I><G><L><D><L><A><L><G><V><G><G><V><P><R><G><R><V><T><E><I><Y><G><P><E><S><S><G><K><T><T><L><T><L><H><I><I><A><E><A><Q><K><R><G><G><T><A><A><F><I><D><A><E><H><A><L><D... | Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP> | P62214 |
Q2FQH4 | PELO_METHJ | Protein pelota homolog | Methanospirillum | <M><K><A><E><I><E><E><L><Q><R><S><F><G><E><I><R><L><F><P><E><N><S><D><D><L><W><H><L><H><N><L><I><T><P><G><S><L><V><Y><A><T><T><L><R><S><V><E><G><S><Q><D><K><I><R><P><E><K><Q><E><K><R><P><V><R><L><G><I><R><V><E><D><V><E><F><H><E><Y><S><I><R><L><R><V><F><G><T><I><E><S><G><V><D><I><G><S><H><H><T><L><N><L><E><P><G><Y><E><I... | May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.<BOP> | Q2FQH4 |
Q57TP3 | DNAK_SALCH | Heat shock protein 70 | Salmonella | <M><G><K><I><I><G><I><D><L><G><T><T><N><S><C><V><A><I><M><D><G><T><Q><A><R><V><L><E><N><A><E><G><D><R><T><T><P><S><I><I><A><Y><T><Q><D><G><E><T><L><V><G><Q><P><A><K><R><Q><A><V><T><N><P><Q><N><T><L><F><A><I><K><R><L><I><G><R><R><F><Q><D><E><E><V><Q><R><D><V><S><I><M><P><Y><K><I><I><G><A><D><N><G><D><A><W><L><D><V><K><G... | Acts as a chaperone.<BOP> | Q57TP3 |
B5RFM6 | UBIB_SALG2 | Ubiquinone biosynthesis protein UbiB | Salmonella | <M><T><P><G><E><V><R><R><L><Y><F><I><I><R><T><F><L><S><Y><G><L><D><E><L><I><P><R><M><R><L><T><L><P><L><R><L><W><R><Y><S><L><F><W><M><P><N><R><H><K><D><K><L><L><G><E><R><L><R><L><A><L><Q><E><L><G><P><V><W><I><K><F><G><Q><M><L><S><T><R><R><D><L><F><P><P><Q><I><A><D><Q><L><A><L><L><Q><D><K><V><A><P><F><D><G><R><L><A><K><A... | Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.<BOP> | B5RFM6 |
E2JA31 | DDAF_ENTAG | ATP-dependent N-fumaramoyl-DAP-amino acid ligase | Pantoea agglomerans group | <M><S><I><L><N><N><K><E><V><I><V><I><I><D><A><W><S><G><G><K><H><L><I><P><A><F><Q><A><L><G><Y><F><C><L><H><V><Q><S><T><F><L><P><E><V><F><I><A><D><N><Q><L><A><I><A><R><S><D><R><H><I><V><H><D><G><N><I><E><T><L><L><S><Q><L><Q><P><Y><T><I><K><A><I><L><A><G><S><E><G><A><V><G><L><A><D><C><L><N><D><A><L><E><L><T><F><S><N><Q><F... | Involved in dapdiamide antibiotics biosynthesis . Ligates N-beta-fumaramoyl-DAP and valine, isoleucine or leucine to form dapdiamides A, B or C, respectively . Also ligates N-beta-epoxysuccinamoyl-DAP and valine to form dapdiamide E .<BOP> | E2JA31 |
Q0AYK2 | PYRH_SYNWW | Uridine monophosphate kinase | Syntrophomonas | <M><Q><K><P><K><Y><K><R><I><V><L><K><L><S><G><E><A><L><A><G><H><N><T><Y><G><I><D><N><E><V><L><N><S><I><A><R><Q><V><V><E><V><V><R><Q><E><V><Q><V><A><I><V><V><G><G><G><N><I><W><R><G><V><A><G><S><A><K><G><M><D><R><A><T><A><D><Y><M><G><M><L><A><T><V><I><N><A><L><A><L><Q><D><A><L><E><Q><E><G><M><G><T><R><V><M><S><A><I><E><M... | Catalyzes the reversible phosphorylation of UMP to UDP.<BOP> | Q0AYK2 |
A8G207 | Y019_PROM2 | Nucleoid-associated protein P9215_00191 | Prochlorococcus | <M><A><G><F><G><L><P><N><F><G><Q><L><T><E><A><F><K><K><A><K><Q><I><Q><Q><D><A><Q><K><L><Q><D><E><L><E><N><M><E><I><E><G><K><S><D><D><E><M><I><K><V><W><I><S><G><N><Q><L><P><L><K><V><E><V><Q><E><N><I><L><N><A><D><K><E><K><I><E><K><N><I><L><Q><A><I><Q><K><A><H><E><S><S><T><T><T><M><K><E><R><M><N><D><L><T><G><G><L><N><L><N... | Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP> | A8G207 |
Q4V0S8 | DNAA_XANC8 | Chromosomal replication initiator protein DnaA | Xanthomonas | <M><D><A><W><P><R><C><L><E><R><L><E><A><E><F><P><P><E><D><V><H><T><W><L><K><P><L><Q><A><E><D><R><G><D><S><I><V><L><Y><A><P><N><A><F><I><V><E><Q><V><R><E><R><Y><L><P><R><I><R><E><L><L><A><Y><F><A><G><N><G><E><V><A><L><A><V><G><S><R><P><R><A><P><E><P><L><P><A><P><Q><A><V><A><S><A><P><A><A><A><P><I><V><P><F><A><G><N><L><D... | Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.<BOP> | Q4V0S8 |
Q0T1H5 | SURE_SHIF8 | Nucleoside monophosphate phosphohydrolase | Shigella | <M><R><I><L><L><S><N><D><D><G><V><H><A><P><G><I><Q><T><L><A><K><A><L><R><E><F><A><D><V><Q><V><V><A><P><D><R><N><R><S><G><A><S><N><S><L><T><L><E><S><S><L><R><T><F><T><F><E><N><G><D><I><A><V><Q><M><G><T><P><T><D><C><V><Y><L><G><V><N><A><L><M><R><P><R><P><D><I><V><V><S><G><I><N><A><G><P><N><L><G><D><D><V><I><Y><S><G><T><V... | Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP. Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-2... | Q0T1H5 |
E9F5F1 | SUBF_METRA | Subglutinol biosynthesis cluster protein E | Metarhizium | <M><T><R><L><S><L><Q><I><I><A><G><L><A><G><Q><A><W><L><V><N><S><D><T><P><S><H><D><A><F><A><S><C><L><S><D><A><S><V><P><I><A><T><K><G><T><P><E><W><T><Q><H><T><T><P><F><N><T><R><L><Q><Y><E><P><I><A><V><A><V><P><T><E><I><S><Q><I><A><A><A><V><T><C><A><K><T><N><G><I><P><V><T><A><K><S><G><G><H><S><F><T><S><L><G><L><G><G><E><D... | FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of the immunosuppressants subglutinols, meroterpenoids consisting of an alpha-pyrone (4-hydroxy-5,6-dimethyl-2-pyrone) moiety attached to a decalin core fused to a five-membered cyclic ether carrying a prenylside chain . The first step o... | E9F5F1 |
Q475Q3 | SURA_CUPPJ | null | Cupriavidus | <M><K><R><Q><E><F><A><L><F><S><L><T><L><M><L><S><P><W><R><R><V><L><L><P><A><V><L><A><A><M><A><G><P><A><L><A><Q><L><K><A><P><S><Q><A><S><R><A><T><G><I><F><V><P><Q><S><S><D><V><A><V><P><S><S><Q><P><Q><L><G><V><P><Q><P><S><S><G><G><K><R><S><Q><L><V><D><E><V><V><A><V><V><N><N><S><V><I><T><R><R><E><L><L><D><R><A><D><E><I><E... | Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps o... | Q475Q3 |
P0AGI3 | RBSC_ECO57 | Ribose import permease protein RbsC | Escherichia | <M><T><T><Q><T><V><S><G><R><R><Y><F><T><K><A><W><L><M><E><Q><K><S><L><I><A><L><L><V><L><I><A><I><V><S><T><L><S><P><N><F><F><T><I><N><N><L><F><N><I><L><Q><Q><T><S><V><N><A><I><M><A><V><G><M><T><L><V><I><L><T><S><G><I><D><L><S><V><G><S><L><L><A><L><T><G><A><V><A><A><S><I><V><G><I><E><V><N><A><L><V><A><V><A><A><A><L><A><L... | Part of the ABC transporter complex RbsABC involved in ribose import. Probably responsible for the translocation of the substrate across the membrane.<BOP> | P0AGI3 |
A3D147 | DPO4_SHEB5 | DNA polymerase IV | Shewanella | <M><R><K><I><I><H><I><D><M><D><C><Y><F><A><A><V><E><M><R><D><F><P><E><Y><R><G><K><P><L><A><V><G><G><S><S><D><R><R><G><V><I><S><T><C><S><Y><E><A><R><K><F><G><V><R><S><A><M><A><T><A><Y><A><F><K><L><C><P><D><L><I><L><V><P><G><R><M><Q><V><Y><K><D><V><S><L><Q><I><R><E><I><F><S><R><Y><T><Q><L><V><E><P><L><S><L><D><E><A><Y><L... | Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in... | A3D147 |
Q4JVB5 | DXS_CORJK | 1-deoxyxylulose-5-phosphate synthase | Corynebacterium | <M><G><I><L><D><K><V><S><S><P><A><D><L><K><G><L><D><A><D><Q><L><E><Q><L><A><A><E><I><R><E><F><L><I><Q><K><V><S><A><T><G><G><H><L><G><P><N><L><G><V><V><E><L><T><I><A><M><H><R><V><F><D><S><P><S><D><P><L><I><F><D><T><G><H><Q><S><Y><V><H><K><I><L><T><G><R><R><D><L><F><D><T><L><R><Q><K><D><G><L><S><G><Y><P><D><R><A><E><S><P... | Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).<BOP> | Q4JVB5 |
Q8U476 | NTPPA_PYRFU | Nucleotide pyrophosphatase | Pyrococcus | <M><K><K><I><I><L><A><S><S><S><P><R><R><R><E><I><L><S><R><F><F><D><I><I><V><H><P><S><N><V><N><E><D><K><I><K><E><K><D><P><T><E><T><A><I><K><I><A><K><A><K><A><F><D><L><A><V><K><F><P><T><D><T><I><I><A><A><D><T><I><V><T><L><N><G><K><I><L><G><K><P><K><D><S><E><E><A><R><K><M><L><K><Q><L><S><G><K><T><H><E><V><V><T><G><Y><C><I... | Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.<BOP> | Q8U476 |
Q65IJ4 | R14Z2_BACLD | 30S ribosomal protein S14 type Z 2 | Bacillus | <M><A><K><T><S><M><I><V><K><Q><K><R><E><Q><K><F><K><V><R><E><Y><T><R><C><E><R><C><G><R><P><H><S><V><I><R><K><F><K><L><C><R><I><C><F><R><E><L><A><Y><K><G><H><I><P><G><V><K><K><A><S><W> | Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.<BOP> | Q65IJ4 |
Q0TL77 | FRSA_ECOL5 | Esterase FrsA | Escherichia | <M><T><Q><A><N><L><S><E><T><L><F><K><P><R><F><K><H><P><E><T><S><T><L><V><R><R><F><S><H><G><A><Q><P><P><V><Q><S><A><L><D><G><K><T><I><P><H><W><Y><R><M><I><N><R><L><M><W><I><W><R><G><I><D><P><R><E><I><L><D><V><Q><A><R><I><V><M><S><D><A><E><R><T><D><D><D><L><Y><D><T><V><I><G><Y><R><G><G><N><W><I><Y><E><W><A><T><Q><A><M><V... | Catalyzes the hydrolysis of esters.<BOP> | Q0TL77 |
P17077 | RL9_RAT | 60S ribosomal protein L9 | Rattus | <M><K><T><I><L><S><N><Q><T><V><D><I><P><E><N><V><D><I><T><L><K><G><R><T><V><I><V><K><G><P><R><G><T><L><R><R><D><F><N><H><I><N><V><E><L><S><L><L><G><K><K><K><K><R><L><R><V><D><K><W><W><G><N><R><K><E><L><A><T><V><R><T><I><C><S><H><V><Q><N><M><I><K><G><V><T><L><G><F><R><Y><K><M><R><S><V><Y><A><H><F><P><I><N><V><V><I><Q><E... | Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.<BOP> | P17077 |
Q4QNB3 | NUDC_HAEI8 | NADH pyrophosphatase | Haemophilus | <M><K><I><L><Q><Q><D><D><F><G><Y><W><L><L><T><Q><G><S><N><L><Y><L><V><N><N><E><L><P><F><G><I><A><K><D><I><D><L><E><G><L><Q><A><M><Q><I><G><E><W><K><N><H><P><L><W><L><V><A><E><Q><E><S><D><E><R><E><Y><V><S><L><R><N><L><L><S><L><P><E><D><E><F><H><I><L><S><R><G><V><E><I><N><H><F><L><K><T><H><K><F><C><G><K><C><G><H><K><T><Q... | mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processin... | Q4QNB3 |
Q9BYE7 | PCGF6_HUMAN | RING finger protein 134 | Homo | <M><E><G><V><A><V><V><T><A><G><S><V><G><A><A><K><T><E><G><A><A><A><L><P><P><P><P><P><V><S><P><P><A><L><T><P><A><P><A><A><G><E><E><G><P><A><P><L><S><E><T><G><A><P><G><C><S><G><S><R><P><P><E><L><E><P><E><R><S><L><G><R><F><R><G><R><F><E><D><E><D><E><E><L><E><E><E><E><E><L><E><E><E><E><E><E><E><E><E><D><M><S><H><F><S><L><R... | Transcriptional repressor . May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase . Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG... | Q9BYE7 |
A9A135 | DNAK_NITMS | Heat shock protein 70 | Nitrosopumilus | <M><G><K><V><I><G><I><D><L><G><T><S><N><S><A><A><A><V><M><M><G><G><K><P><T><I><I><P><A><A><E><G><Q><T><A><A><G><K><A><F><P><S><V><V><A><F><S><K><E><G><E><L><L><V><G><E><P><A><R><R><Q><A><V><T><N><P><D><N><T><I><I><A><A><K><R><K><M><G><S><D><Y><T><F><K><I><Q><D><K><E><Y><K><P><Q><Q><I><S><S><F><I><L><Q><K><I><K><K><D><A... | Acts as a chaperone.<BOP> | A9A135 |
Q4ULR6 | ISPT_RICFE | Isoprenyl transferase | spotted fever group | <M><Q><Q><H><L><K><Y><K><I><M><T><N><I><K><H><L><A><I><I><M><D><G><N><A><R><W><A><D><Q><H><N><L><T><K><S><E><G><H><K><A><G><A><D><K><I><R><E><L><L><P><E><F><I><N><L><N><I><P><Y><I><T><L><Y><T><F><S><S><E><N><W><Q><R><S><S><T><E><V><D><F><L><I><K><L><L><S><I><Y><F><K><N><E><L><N><S><L><H><K><N><G><V><K><I><K><V><I><G><R... | Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.<BOP> | Q4ULR6 |
B1WBM3 | TM138_RAT | Transmembrane protein 138 | Rattus | <M><L><Q><T><S><N><Y><S><L><V><L><S><L><Q><F><L><L><L><C><Y><D><L><F><V><N><S><F><S><E><L><L><R><M><A><P><V><I><Q><L><V><L><F><I><I><Q><D><I><A><I><L><F><N><I><I><I><I><F><L><M><F><F><N><T><F><V><F><Q><A><G><L><V><N><L><L><F><H><K><F><K><G><T><I><I><L><T><S><V><Y><L><A><L><S><I><S><L><H><V><W><V><M><N><V><R><W><K><D><S... | Required for ciliogenesis.<BOP> | B1WBM3 |
Q47279 | HRPN_PECCC | Harpin-Ecc | Pectobacterium | <M><L><N><S><L><G><G><G><A><S><L><Q><I><T><I><K><A><G><G><N><G><G><L><F><P><S><Q><S><S><Q><N><G><G><S><P><S><Q><S><A><F><G><G><Q><R><S><N><I><A><E><Q><L><S><D><I><M><T><T><M><M><F><M><G><S><M><M><G><G><G><M><S><G><G><L><G><G><L><G><S><S><L><G><G><L><G><G><G><L><L><G><G><G><L><G><G><G><L><G><S><S><L><G><S><G><L><G><S><A... | Elicits the hypersensitive response (HR) in the plant upon infection. Harpin elicits HR in non-hosts and is also required for pathogenicity in host plants.<BOP> | Q47279 |
O08537 | ESR2_MOUSE | Nuclear receptor subfamily 3 group A member 2 | Mus | <M><E><I><K><N><S><P><S><S><L><T><S><P><A><S><Y><N><C><S><Q><S><I><L><P><L><E><H><G><P><I><Y><I><P><S><S><Y><V><E><S><R><H><E><Y><S><A><M><T><F><Y><S><P><A><V><M><N><Y><S><V><P><S><S><T><G><N><L><E><G><G><P><V><R><Q><T><A><S><P><N><V><L><W><P><T><S><G><H><L><S><P><L><A><T><H><C><Q><S><S><L><L><Y><A><E><P><Q><K><S><P><W... | Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.<BOP> | O08537 |
B3E3I1 | PYRC_TRIL1 | Dihydroorotase | Trichlorobacter | <M><N><L><L><I><K><G><G><R><V><I><D><P><S><Q><G><I><D><D><T><L><D><V><V><V><E><N><G><L><V><K><E><I><G><K><G><L><A><T><S><A><G><A><E><T><I><D><A><S><G><K><Y><V><V><P><G><L><I><D><M><H><V><H><L><R><D><P><G><L><E><Y><K><E><D><I><I><S><G><T><R><A><A><V><A><G><G><F><T><S><V><C><C><M><P><N><T><K><P><A><I><D><N><K><A><I><A><S... | Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.<BOP> | B3E3I1 |
Q74JY0 | SEPF_LACJO | Cell division protein SepF | Lactobacillus | <M><A><F><D><K><L><G><R><F><F><G><I><S><E><D><D><E><M><N><E><V><P><Y><T><E><S><E><E><Q><Q><E><E><I><P><Q><T><Q><K><N><E><R><R><A><N><V><V><S><I><N><S><G><V><S><A><T><S><K><I><V><L><Y><E><P><R><V><Y><S><D><A><K><E><V><A><Q><N><L><L><N><N><K><A><V><I><I><N><F><A><R><M><D><D><E><Q><A><R><R><I><V><D><F><I><T><G><T><V><Y><A... | Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.<BOP> | Q74JY0 |
B9LPV1 | RFCL_HALLT | Clamp loader large subunit | Halorubrum | <M><A><D><W><T><E><K><Y><R><P><S><T><L><S><E><V><R><G><N><D><K><A><R><D><A><F><A><D><W><A><R><S><W><D><D><H><H><E><A><V><V><L><H><G><S><P><G><V><G><K><T><S><A><A><H><A><L><A><N><D><M><G><W><E><T><V><E><L><N><A><S><D><Q><R><T><A><D><V><I><E><R><F><A><G><R><A><A><R><N><A><T><L><G><G><S><A><A><G><G><G><A><A><G><G><D><T><A... | Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.<BOP> | B9LPV1 |
Q1LLK0 | HISZ_CUPMC | ATP phosphoribosyltransferase regulatory subunit | Cupriavidus | <M><S><N><R><W><L><L><P><E><N><I><A><D><V><L><P><S><E><A><R><K><I><E><E><L><R><R><R><M><L><D><L><F><R><T><Y><G><Y><E><L><V><M><P><P><M><L><E><Y><L><E><S><L><L><T><G><T><G><H><D><L><D><L><R><T><L><K><L><V><D><Q><L><S><G><R><T><L><G><L><R><A><D><I><T><P><Q><V><A><R><I><D><A><H><L><L><N><R><P><G><V><T><R><L><C><Y><A><G><N... | Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.<BOP> | Q1LLK0 |
Q3BPR2 | PEPQ_XANC5 | Proline dipeptidase | Xanthomonas | <M><P><Q><P><S><L><S><S><L><Y><S><D><H><L><R><T><L><T><A><R><A><D><E><A><L><Q><R><G><G><F><E><H><L><V><V><P><S><G><S><T><H><Y><Q><L><F><D><D><R><D><Y><P><Y><A><V><N><P><Q><F><K><A><W><V><P><L><T><R><V><P><N><S><W><L><V><Y><T><P><G><K><R><P><T><V><I><F><Y><Q><P><F><D><Y><W><H><V><V><P><D><A><P><S><G><W><W><V><D><H><C><D... | Splits dipeptides with a prolyl residue in the C-terminal position.<BOP> | Q3BPR2 |
Q67JD0 | PTH_SYMTH | Peptidyl-tRNA hydrolase | Symbiobacterium | <M><A><K><L><I><V><G><L><G><N><P><G><P><R><Y><A><A><T><R><H><N><A><G><W><M><L><L><D><A><F><A><R><K><H><G><V><A><I><E><Q><R><G><F><E><G><L><Y><G><E><L><R><W><G><A><E><A><E><K><V><I><L><L><K><P><L><T><Y><M><N><L><S><G><R><S><V><A><Q><A><A><R><F><Y><R><I><A><P><A><D><I><L><V><L><F><D><D><L><D><L><E><P><G><R><L><R><L><R><A... | The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.<BOP> | Q67JD0 |
P58818 | PHR_METTM | Photoreactivating enzyme | Methanothermobacter | <M><I><H><D><E><R><I><R><S><L><N><T><E><K><P><A><R><D><G><K><Y><V><I><Y><W><M><Q><A><S><V><R><A><H><W><N><H><A><L><E><Y><A><I><E><T><A><N><S><L><H><K><P><L><I><V><I><F><G><L><T><D><E><F><P><N><A><N><S><R><H><Y><R><F><L><I><E><G><L><R><D><V><G><D><A><L><M><K><R><G><A><R><L><V><V><E><N><E><R><P><P><S><A><V><M><R><Y><S><D... | Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation.<BOP> | P58818 |
P9WEV6 | PAPS_PHOAM | Methyl phomopsenonate biosynthesis cluster protein PaPS | Diaporthe | <M><E><Y><R><Y><S><Y><V><I><D><P><S><S><Y><D><N><Q><G><L><C><N><G><I><P><L><R><V><H><R><N><A><D><I><E><E><Y><A><T><I><S><L><R><N><D><W><R><K><H><V><G><P><L><P><L><T><S><Y><G><G><N><L><G><P><K><Y><N><F><T><A><V><T><L><P><E><C><R><P><D><R><L><E><I><V><S><Y><I><M><E><F><A><F><L><H><D><D><L><V><D><T><A><Q><V><D><E><A><L><A... | Bifunctional terpene synthase; part of the gene cluster that mediates the biosynthesis of the diterpene methyl phomopsenonate . At first, the universal precursor of diterpene, geranylgeranyl diphosphate (GGPP) is provided and is cyclized by the unusual bifunctional terpene synthase PaPS to give phomopsene . The C-termi... | P9WEV6 |
A8GAP2 | DXS_SERP5 | 1-deoxyxylulose-5-phosphate synthase | Serratia | <M><S><L><D><I><A><K><Y><P><T><L><A><L><A><E><N><P><D><E><L><R><S><L><P><K><E><S><L><P><K><L><C><D><E><L><R><Q><Y><L><L><D><S><V><S><R><S><S><G><H><F><A><S><G><L><G><T><V><E><L><T><V><A><L><H><Y><V><Y><Q><T><P><F><D><H><L><V><W><D><V><G><H><Q><A><Y><P><H><K><I><L><T><G><R><R><D><K><I><A><T><I><R><Q><K><N><G><L><H><P><F... | Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).<BOP> | A8GAP2 |
A0QVY5 | LEXA_MYCS2 | LexA repressor | Mycolicibacterium | <M><S><D><D><T><G><E><F><T><D><G><S><T><E><S><P><A><D><A><D><G><A><G><R><R><R><A><V><D><N><G><L><T><E><R><Q><R><T><I><L><E><V><I><R><A><S><V><T><S><R><G><Y><P><P><S><I><R><E><I><G><D><A><V><G><L><T><S><T><S><S><V><A><H><Q><L><R><T><L><E><R><K><G><Y><L><R><R><D><P><N><R><P><R><A><V><D><V><R><A><A><D><D><P><A><A><A><A><V... | Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair... | A0QVY5 |
B7GTU6 | GATA_BIFLS | Glutamyl-tRNA(Gln) amidotransferase subunit A | Bifidobacterium | <M><S><N><E><T><A><T><L><V><K><L><S><A><A><E><Q><A><A><A><I><K><K><G><D><V><T><S><R><E><L><V><E><A><H><L><K><V><I><E><A><A><E><P><S><I><K><A><F><L><K><V><S><G><D><V><A><L><E><Q><A><D><A><F><D><A><K><S><A><E><D><K><A><A><L><P><E><L><A><G><V><P><I><A><I><K><D><M><I><V><T><K><G><I><E><T><T><A><A><S><K><I><L><E><G><W><V><P... | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).<BOP> | B7GTU6 |
G5ED45 | HYL1_CAEEL | Ceramide synthase hyl-1 | Caenorhabditis | <M><W><R><M><S><Y><F><W><H><E><P><Y><W><L><P><R><N><V><T><W><P><E><V><P><A><K><F><V><D><L><L><V><P><I><Y><L><A><I><P><L><V><I><I><R><I><L><W><E><S><T><I><G><V><T><Y><L><Y><F><R><T><N><A><Y><A><S><R><K><N><I><T><L><L><G><C><M><W><E><H><M><T><G><G><F><A><S><V><S><R><A><K><K><I><L><E><C><F><W><R><F><S><Y><Y><T><F><A><F><L... | Catalyzes the acylation of sphingoid bases to form ceramides. Sphingolipids from Caenorhabditis elegans contain exclusively isosphingoid bases. Exhibits substrate preference for fatty acyl-coA chains containing 24 and 26 carbons.<BOP> | G5ED45 |
Q9ZLZ7 | SYE1_HELPJ | Glutamyl-tRNA synthetase 1 | Helicobacter | <M><S><L><I><V><T><R><F><A><P><S><P><T><G><Y><L><H><I><G><G><L><R><T><A><I><F><N><Y><L><F><A><R><A><N><Q><G><K><F><F><L><R><I><E><D><T><D><L><S><R><N><S><I><E><A><A><N><A><I><V><E><A><F><K><W><V><G><L><E><H><D><G><E><I><L><Y><Q><S><K><R><F><E><I><Y><K><E><Y><I><Q><K><L><L><D><E><D><K><A><Y><Y><C><Y><M><S><K><E><E><L><D... | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP> | Q9ZLZ7 |
Q8D0W8 | CYSA_YERPE | Sulfate-transporting ATPase | Yersinia | <M><S><I><E><I><N><N><I><S><K><Y><F><G><R><T><K><V><L><N><D><I><T><L><D><I><P><S><G><Q><M><V><A><L><L><G><P><S><G><S><G><K><T><T><L><L><R><I><I><A><G><L><E><N><Q><N><A><G><R><L><S><F><H><G><T><D><V><S><R><L><H><A><R><D><R><R><V><G><F><V><F><Q><H><Y><A><L><F><R><H><M><T><V><F><D><N><I><A><F><G><L><T><V><L><P><R><R><E><R... | Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system.<BOP> | Q8D0W8 |
Q59Q46 | IMDH_CANAL | Inosine-5'-monophosphate dehydrogenase | Candida | <M><V><F><E><T><S><K><A><T><S><Y><L><K><D><Y><P><K><K><D><G><L><S><V><K><E><L><I><D><S><T><N><F><G><G><L><T><Y><N><D><F><L><I><L><P><G><L><I><N><F><P><S><S><A><V><S><L><E><T><K><L><T><K><K><I><T><L><K><S><P><F><V><S><S><P><M><D><T><V><T><E><E><N><M><A><I><H><M><A><L><L><G><G><I><G><I><I><H><H><N><C><T><S><E><E><Q><A><E... | Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.<BOP> | Q59Q46 |
Q39617 | POR_CHLRE | NADPH-protochlorophyllide oxidoreductase | Chlamydomonas | <M><A><L><T><M><S><A><K><S><V><S><A><R><A><Q><V><S><S><K><A><Q><A><A><P><A><V><A><V><S><G><R><T><S><S><R><V><M><P><A><P><A><L><A><A><R><S><S><V><A><R><T><P><L><V><V><C><A><A><T><A><T><A><P><S><P><S><L><A><D><K><F><K><P><N><A><I><A><R><V><P><A><T><Q><Q><K><Q><T><A><I><I><T><G><A><S><S><G><L><G><L><N><A><A><K><A><L><A><A... | Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).<BOP> | Q39617 |
A6WC46 | COXX_KINRD | Heme O synthase | Kineococcus | <M><T><V><A><D><P><R><L><T><D><A><P><A><H><S><R><T><S><L><L><G><R><R><R><G><G><R><P><P><R><F><P><R><A><A><A><Y><V><A><L><T><K><P><R><I><V><E><L><L><L><I><T><T><I><P><V><M><L><F><A><A><G><G><L><P><S><G><W><L><I><L><T><T><F><V><G><G><A><L><A><A><G><C><A><N><T><L><N><C><Y><F><D><R><D><I><D><A><L><M><K><R><T><E><N><R><P><L... | Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.<BOP> | A6WC46 |
Q8TQ68 | SYDND_METAC | Non-discriminating aspartyl-tRNA synthetase | Methanosarcina | <M><S><L><A><N><L><R><T><H><Y><T><A><E><V><K><P><E><S><V><D><N><G><Q><K><I><T><L><A><G><W><I><H><E><V><R><D><L><G><G><I><C><F><V><V><L><R><D><R><E><G><K><A><Q><V><T><L><V><K><K><K><I><D><K><E><L><F><D><A><A><R><R><L><I><R><E><S><V><I><S><V><T><G><S><V><K><F><E><E><K><A><P><N><G><Y><E><L><L><P><E><E><I><K><V><L><N><V><A... | Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).<BOP> | Q8TQ68 |
Q9ZP55 | DRP4C_ARATH | Dynamin-related protein 4C | Arabidopsis | <M><V><K><K><K><V><A><T><K><K><N><S><P><S><L><A><I><A><K><K><K><S><R><S><N><K><D><V><V><S><V><E><A><P><I><I><S><S><Y><N><D><R><I><R><P><L><L><D><T><V><D><R><L><R><N><L><N><V><M><R><E><G><I><H><L><P><T><I><V><V><V><G><D><Q><S><S><G><K><S><S><V><L><E><S><L><A><G><I><S><L><P><R><G><Q><G><I><C><T><R><V><P><L><V><M><R><L><Q... | Putative microtubule-associated force-producing protein, able to bind and hydrolyze GTP.<BOP> | Q9ZP55 |
A1VX91 | ILVD_CAMJJ | Dihydroxy-acid dehydratase | Campylobacter | <M><R><S><D><A><I><K><K><G><H><L><K><A><P><N><R><S><L><L><R><A><C><G><L><K><D><E><D><F><D><K><P><F><I><G><V><A><N><S><Y><I><D><I><I><P><G><H><Y><F><L><N><D><Y><A><K><I><I><K><D><E><I><R><K><N><G><C><V><P><F><E><F><N><T><I><G><V><D><D><G><I><A><M><G><H><E><G><M><L><Y><S><L><P><S><R><E><I><I><A><N><S><I><E><T><V><M><N><A... | Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (... | A1VX91 |
Q1LLX0 | RS18_CUPMC | 30S ribosomal protein S18 | Cupriavidus | <M><A><F><V><K><R><D><N><K><N><K><K><R><F><Q><Q><Q><N><P><L><F><K><R><K><R><F><C><R><F><T><V><A><G><V><E><Q><I><D><Y><K><D><L><D><T><L><K><D><F><I><G><D><N><G><K><I><T><P><A><R><L><T><G><T><K><A><H><Y><Q><R><Q><L><D><T><A><I><K><R><A><R><F><L><A><L><M><P><Y><T><D><L><H><K><N> | Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.<BOP> | Q1LLX0 |
P01877 | IGHA2_HUMAN | Ig alpha-2 chain C region LAN | Homo | <A><S><P><T><S><P><K><V><F><P><L><S><L><D><S><T><P><Q><D><G><N><V><V><V><A><C><L><V><Q><G><F><F><P><Q><E><P><L><S><V><T><W><S><E><S><G><Q><N><V><T><A><R><N><F><P><P><S><Q><D><A><S><G><D><L><Y><T><T><S><S><Q><L><T><L><P><A><T><Q><C><P><D><G><K><S><V><T><C><H><V><K><H><Y><T><N><S><S><Q><D><V><T><V><P><C><R><V><P><P><P><P... | Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the cl... | P01877 |
Q1I2W1 | XPT_PSEE4 | Xanthine phosphoribosyltransferase | Pseudomonas | <M><E><A><L><Q><Q><K><I><R><E><E><G><I><V><L><S><D><Q><V><L><K><V><D><A><F><L><N><H><Q><I><D><P><A><L><M><Q><L><I><G><D><E><F><A><R><L><F><A><D><S><G><V><T><K><I><V><T><I><E><A><S><G><I><A><P><A><V><M><T><G><L><K><L><G><V><P><V><I><F><A><R><K><H><Q><S><L><T><L><T><E><N><L><L><T><A><S><V><Y><S><F><T><K><Q><T><E><N><T><V... | Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP> | Q1I2W1 |
A1KWK2 | SSTT_NEIMF | Na(+)/serine-threonine symporter | Neisseria | <M><A><F><G><K><S><L><F><H><A><I><G><R><V><S><L><V><R><Q><I><A><A><G><L><A><L><G><I><V><I><G><S><V><S><P><Q><L><G><L><A><A><G><L><F><G><S><L><F><V><G><A><L><K><A><V><A><P><V><L><V><F><I><L><V><A><A><T><I><A><Q><H><Q><K><G><N><K><A><H><I><R><P><I><I><V><L><Y><L><I><G><T><F><S><A><A><L><T><A><V><I><A><G><M><V><F><P><T><H... | Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).<BOP> | A1KWK2 |
A0KMH0 | LPLA_AERHH | Lipoate--protein ligase | Aeromonas | <M><S><R><L><R><L><L><L><S><D><S><H><D><P><L><F><N><L><A><V><E><E><C><I><F><R><Q><M><D><P><N><Q><R><V><L><F><L><W><R><N><A><N><T><V><V><I><G><R><A><Q><N><P><W><K><E><C><N><T><R><R><M><E><E><D><G><V><T><L><A><R><R><S><S><G><G><G><A><V><F><H><D><L><G><N><S><C><F><T><F><M><A><G><K><P><E><Y><D><K><S><V><S><T><A><I><V><L><D... | Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.<BOP> | A0KMH0 |
Q1GSA0 | NDK_SPHAL | Nucleoside-2-P kinase | Sphingopyxis | <M><A><V><T><R><T><F><S><I><I><K><P><D><A><T><R><R><N><L><T><G><A><V><T><K><M><L><E><D><A><G><L><R><V><V><A><S><K><R><I><H><M><T><R><E><Q><A><E><G><F><Y><A><V><H><K><E><R><P><F><F><G><E><L><V><E><F><M><I><S><G><P><V><V><V><Q><V><L><E><G><E><D><A><V><K><R><N><R><D><V><M><G><A><T><N><P><A><D><A><A><E><G><T><I><R><K><T><F... | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.<BOP> | Q1GSA0 |
Q9RVP2 | CATNT_DEIRA | CC-adding enzyme | Deinococcus | <M><A><T><P><D><G><E><Q><V><W><A><Q><L><Q><P><Q><D><R><A><W><L><N><D><L><S><R><R><A><G><P><D><T><E><L><A><L><V><G><G><A><V><R><D><A><L><L><G><Q><T><P><L><D><L><D><I><V><V><A><G><Q><D><G><Q><G><V><E><A><L><A><L><A><S><G><L><P><F><V><F><H><P><A><F><E><N><A><T><L><T><L><P><D><G><R><G><A><D><L><V><R><A><R><R><E><H><Y><P><Q... | tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. Adds the two cytidine residues to tRNA.<BOP> | Q9RVP2 |
Q382H9 | COQ4_TRYB2 | Coenzyme Q biosynthesis protein 4 homolog | Trypanosoma | <M><Q><S><R><V><V><S><S><A><V><M><F><L><G><G><I><A><G><A><V><K><S><L><P><A><F><V><T><S><S><F><G><A><I><V><D><P><E><D><G><R><G><S><A><A><F><A><E><I><T><A><L><T><A><L><H><H><M><Q><R><L><M><M><A><D><E><M><G><R><S><I><L><K><E><R><P><Q><V><T><D><E><T><L><E><F><A><K><T><Q><P><E><G><T><F><G><Y><R><Y><A><A><F><M><K><R><N><N><F... | Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.<BOP> | Q382H9 |
Q72E53 | TGT_DESVH | tRNA-guanine transglycosylase | Desulfovibrio | <M><T><T><P><G><T><F><E><I><H><A><T><D><G><A><A><R><T><G><C><L><H><T><A><H><G><I><V><R><T><P><I><F><M><P><V><G><T><V><G><S><V><K><A><I><A><P><D><D><L><E><A><I><G><A><E><I><I><L><G><N><T><Y><H><L><Y><L><R><P><G><D><E><L><V><A><R><R><G><G><L><H><E><F><N><A><W><R><K><P><I><L><T><D><S><G><G><F><Q><V><F><S><L><S><G><L><R><R... | Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th... | Q72E53 |
Q1LTY2 | RPOZ_BAUCH | Transcriptase subunit omega | Candidatus Baumannia | <M><A><R><I><T><V><Q><D><A><V><E><K><I><G><N><R><F><N><L><V><L><I><A><A><R><R><A><R><Q><I><Q><I><N><G><K><D><P><L><V><P><E><K><N><D><K><S><T><V><I><A><L><R><E><I><E><Q><G><L><I><G><N><Q><I><I><D> | Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP> | Q1LTY2 |
C6DFR6 | FMT_PECCP | Methionyl-tRNA formyltransferase | Pectobacterium | <M><S><D><S><L><R><I><I><F><A><G><T><P><D><F><A><A><R><H><L><D><A><L><L><S><S><G><H><E><V><V><G><V><F><T><Q><P><D><R><P><A><G><R><G><N><K><L><T><P><S><P><V><K><V><L><A><E><Q><H><N><I><P><I><F><Q><P><K><S><L><R><P><A><E><N><Q><A><M><V><Q><A><L><D><A><D><V><M><V><V><V><A><Y><G><L><I><L><P><Q><P><V><L><S><M><P><R><L><G><C... | Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.<BOP> | C6DFR6 |
B4SJS0 | ATPG_STRM5 | F-ATPase gamma subunit | Stenotrophomonas maltophilia group | <M><A><S><G><R><E><I><K><T><K><I><K><S><V><Q><N><T><R><K><V><T><R><A><L><E><M><V><S><A><S><K><I><R><K><A><Q><D><R><M><K><T><S><R><P><Y><A><Q><A><M><K><Q><V><I><G><H><L><A><Q><A><S><T><D><Y><Q><H><P><F><L><V><E><R><E><Q><V><K><R><V><G><F><I><V><I><S><S><D><R><G><L><A><G><G><L><N><N><N><L><F><R><K><L><L><G><E><A><K><A><W... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP> | B4SJS0 |
A3N2A1 | RPIA_ACTP2 | Phosphoriboisomerase A | Actinobacillus | <M><T><Q><Q><E><M><K><K><I><A><A><Q><A><A><L><Q><F><V><K><P><D><T><I><V><G><V><G><S><G><S><T><V><N><C><F><I><D><A><L><A><S><M><K><D><Q><I><K><G><A><V><A><A><S><K><A><S><E><E><R><L><R><A><I><G><I><E><V><F><N><A><N><E><V><S><E><L><D><V><Y><I><D><G><A><D><E><I><T><P><Q><G><A><M><I><K><G><G><G><A><A><L><T><R><E><K><I><V><S... | Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.<BOP> | A3N2A1 |
A8EZN9 | DER_RICCK | GTP-binding protein EngA | belli group | <M><T><K><Q><I><I><A><L><V><G><R><P><N><V><G><K><S><T><L><F><N><R><L><S><I><R><K><K><A><I><V><H><N><L><P><G><V><T><R><D><R><K><Y><T><D><G><K><I><G><S><C><E><F><L><L><I><D><T><P><G><L><E><E><N><P><N><S><M><S><V><R><L><M><E><Q><T><T><K><A><I><L><E><A><D><L><I><C><F><M><V><D><C><R><S><G><I><L><P><D><D><K><L><L><S><S><F><I... | GTPase that plays an essential role in the late steps of ribosome biogenesis.<BOP> | A8EZN9 |
P29017 | CD1C_HUMAN | T-cell surface glycoprotein CD1c | Homo | <M><L><F><L><Q><F><L><L><L><A><L><L><L><P><G><G><D><N><A><D><A><S><Q><E><H><V><S><F><H><V><I><Q><I><F><S><F><V><N><Q><S><W><A><R><G><Q><G><S><G><W><L><D><E><L><Q><T><H><G><W><D><S><E><S><G><T><I><I><F><L><H><N><W><S><K><G><N><F><S><N><E><E><L><S><D><L><E><L><L><F><R><F><Y><L><F><G><L><T><R><E><I><Q><D><H><A><S><Q><D><Y... | Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.<BOP> | P29017 |
Q5L686 | RUVB_CHLAB | Holliday junction ATP-dependent DNA helicase RuvB | Chlamydia | <M><T><H><Q><V><S><V><L><H><Q><D><K><K><F><D><V><S><L><R><P><K><G><L><K><E><F><C><G><Q><A><Q><L><T><E><R><L><E><L><F><L><N><A><A><I><Q><R><G><E><V><P><G><H><C><L><F><F><G><P><P><G><L><G><K><T><S><L><A><H><I><V><A><N><T><V><G><K><G><L><L><V><A><S><G><P><Q><L><V><K><P><S><D><L><L><G><L><L><T><S><L><Q><E><G><D><V><F><F><I... | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.<BOP> | Q5L686 |
Q5U203 | UBE2F_RAT | Ubiquitin-conjugating enzyme E2 F | Rattus | <M><L><T><L><A><S><K><L><K><R><D><D><G><L><K><G><S><R><A><S><A><S><T><S><D><S><T><R><R><V><S><V><R><D><K><L><L><V><K><E><V><A><E><L><E><A><N><L><P><C><T><C><K><V><H><F><P><D><P><N><K><L><H><C><F><Q><L><T><V><S><P><D><E><G><Y><Y><Q><G><G><K><F><Q><F><E><T><E><V><P><D><A><Y><N><M><V><P><P><K><V><K><C><L><T><K><I><W><H><P... | Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.<BOP> | Q5U203 |
Q9FIL1 | BSK5_ARATH | Brassinosteroid-signaling kinase 5 | Arabidopsis | <M><G><P><R><C><S><K><L><S><L><C><W><W><P><T><H><L><K><S><T><H><N><E><A><S><D><L><D><N><G><T><D><D><L><P><S><F><T><E><F><S><F><D><Q><L><R><A><A><T><C><G><F><S><T><D><S><I><V><S><E><H><G><V><K><A><P><N><V><V><Y><K><G><R><L><E><D><D><R><W><I><A><V><K><R><F><N><R><S><A><W><P><D><T><R><Q><F><L><E><E><A><K><A><V><G><Q><L><R... | Probable serine/threonine kinase that acts as positive regulator of brassinosteroid (BR) signaling downstream of the receptor kinase BRI1 . Involved in abiotic stress tolerance. Required for salt stress and abscisic acid-mediated drought stress tolerance .<BOP> | Q9FIL1 |
Q93Z37 | BIG1E_ARATH | Protein BIG GRAIN 1-like E | Arabidopsis | <M><S><M><K><G><I><S><S><A><E><S><D><K><L><S><R><R><I><S><L><T><H><K><R><N><S><E><E><L><D><V><F><E><A><A><V><Y><F><G><Y><N><E><A><S><S><G><D><H><G><H><T><Q><K><Y><G><Y><N><A><A><R><E><E><N><P><R><R><W><G><I><L><G><G><G><R><R><I><S><L><D><L><P><I><R><C><S><E><Q><V><Y><H><L><Q><Q><D><H><H><E><K><H><E><V><T><T><I><K><E><R... | Involved in auxin transport. Regulator of the auxin signaling pathway.<BOP> | Q93Z37 |
Q6F1Z6 | DEOC1_MESFL | Phosphodeoxyriboaldolase 1 | Mesoplasma | <M><K><L><N><K><Y><I><D><H><T><L><L><K><Q><D><A><T><K><A><E><I><K><Q><L><C><D><E><A><I><E><F><D><F><A><T><V><C><V><N><S><Y><W><T><S><Y><C><K><E><L><L><K><G><T><N><V><G><I><T><N><V><V><G><F><P><L><G><A><C><T><T><A><T><K><A><F><E><V><S><E><A><I><K><D><G><A><T><E><I><D><M><V><L><N><I><G><A><L><K><D><K><N><Y><E><L><V><L><E... | Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.<BOP> | Q6F1Z6 |
D3ZFB6 | PRRT2_RAT | Dispanin subfamily B member 3 | Rattus | <M><A><A><S><S><S><E><V><S><E><M><K><G><V><E><D><S><S><N><T><H><S><E><G><P><R><H><S><E><E><G><M><G><P><V><Q><V><V><A><E><N><L><D><Q><P><E><A><L><Q><S><G><P><D><T><T><A><A><P><V><D><S><G><P><K><A><E><L><A><P><E><T><T><E><T><P><V><E><T><P><E><T><V><Q><A><T><D><L><S><V><N><P><G><E><D><S><K><T><C><P><S><P><K><E><A><C><Q><E... | As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE... | D3ZFB6 |
A0RQU7 | EFTS_CAMFF | Elongation factor Ts | Campylobacter | <M><E><I><S><A><S><M><V><K><E><L><R><E><S><T><G><A><G><M><M><D><C><K><K><A><L><Q><E><S><N><G><D><M><Q><K><A><V><D><I><L><R><E><K><G><L><G><K><A><A><K><K><A><D><R><L><A><S><E><G><L><V><S><V><V><V><S><E><N><N><K><T><A><T><I><T><E><I><N><S><E><T><D><F><V><A><K><N><A><T><F><V><D><L><V><K><N><T><T><I><H><V><Q><T><N><S><I><N... | Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.<BOP> | A0RQU7 |
Q99R75 | CRTM_STAAM | Dehydrosqualene synthase | Staphylococcus | <M><T><M><M><D><M><N><F><K><Y><C><H><K><I><M><K><K><H><S><K><S><F><S><Y><A><F><D><L><L><P><E><D><Q><R><K><A><V><W><A><I><Y><A><V><C><R><K><I><D><D><S><I><D><V><Y><G><D><I><Q><F><L><N><Q><I><K><E><D><I><Q><S><I><E><K><Y><P><Y><E><H><H><H><F><Q><S><D><R><R><I><M><M><A><L><Q><H><V><A><Q><H><K><N><I><A><F><Q><S><F><Y><N><L... | Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress. Catalyzes the head-to-head condensation of two molecules of farnesyl diphosphate (FPP) into the colorless C(30) carotenoid 4,4'-diapophytoene (dehydrosq... | Q99R75 |
B4EXE3 | CH10_PROMH | Chaperonin-10 | Proteus | <M><K><I><R><P><L><H><D><R><V><I><V><K><R><K><E><V><E><A><K><S><A><G><G><I><V><L><T><G><S><A><A><G><K><S><T><R><G><E><I><L><A><V><G><N><G><R><I><M><E><N><G><E><V><K><P><L><D><V><K><V><G><D><I><V><I><F><N><D><G><Y><G><V><K><S><E><K><I><D><N><E><D><V><L><I><M><S><E><S><D><I><L><A><I><V><E><A> | Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of ... | B4EXE3 |
Q9EPQ7 | STAR5_MOUSE | START domain-containing protein 5 | Mus | <M><D><P><S><W><A><T><Q><E><S><E><A><V><A><E><K><V><L><R><Y><R><R><D><A><S><G><W><K><K><C><R><E><G><N><G><V><S><I><S><W><R><P><S><E><E><F><P><G><N><L><Y><R><G><E><G><I><L><C><G><T><P><E><E><V><W><D><C><I><K><P><V><A><S><G><L><R><E><K><W><D><D><N><V><S><S><F><E><I><V><Q><S><I><T><D><M><L><C><V><S><R><T><S><T><P><S><A><A... | May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.<BOP> | Q9EPQ7 |
P81543 | FERA_SULME | Seven-iron ferredoxin | Sulfuracidifex | <G><I><D><P><N><Y><R><T><S><R><P><E><V><G><T><H><E><G><H><K><V><Y><G><P><V><E><N><P><K><V><L><G><I><H><G><A><I><V><G><V><D><F><D><L><C><I><A><D><G><S><C><I><N><A> | Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.<BOP> | P81543 |
B2HED8 | G6PI_MYCMM | Phosphohexose isomerase | Mycobacterium | <M><T><S><E><Q><S><I><P><D><I><T><A><T><P><A><W><E><A><L><R><K><H><H><D><Q><I><G><E><T><H><L><R><Q><I><F><A><D><D><P><N><R><G><H><D><L><T><V><T><V><G><D><L><Y><I><D><Y><S><K><H><R><I><T><R><D><T><I><S><L><L><V><D><L><A><R><T><A><N><L><E><A><H><R><D><Q><M><F><A><G><A><H><I><N><T><S><E><D><R><A><V><L><H><T><A><L><R><L><P... | Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.<BOP> | B2HED8 |
A8Z668 | RL3_SULMW | 50S ribosomal protein L3 | Candidatus Sulcia | <M><S><G><I><I><G><K><N><I><G><M><T><S><M><Y><D><E><S><G><F><N><V><P><C><S><I><I><E><A><G><P><C><I><V><L><Q><I><K><T><K><E><K><D><G><Y><D><S><C><Q><L><G><F><D><E><K><K><Y><K><N><T><N><K><P><L><L><F><F><F><K><K><F><K><S><T><P><K><K><K><I><F><E><L><P><I><K><G><N><I><K><S><G><N><I><I><K><L><N><C><F><H><E><N><E><L><V><N><I... | One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP> | A8Z668 |
A0KGR9 | MUTL_AERHH | DNA mismatch repair protein MutL | Aeromonas | <M><P><I><R><I><L><P><P><I><L><A><N><Q><I><A><A><G><E><V><V><E><R><P><S><S><V><V><K><E><L><V><E><N><S><L><D><A><G><A><D><R><V><E><I><D><I><D><K><G><G><A><K><L><I><R><I><R><D><N><G><S><G><V><A><K><D><E><L><V><L><A><L><S><R><H><A><T><S><K><V><A><T><L><D><D><L><E><G><I><N><S><L><G><F><R><G><E><A><L><A><S><I><S><S><V><S><R... | This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part ... | A0KGR9 |
Q9LTH3 | U76E1_ARATH | UDP-glycosyltransferase 76E1 | Arabidopsis | <M><E><E><L><G><V><K><R><R><I><V><L><V><P><V><P><A><Q><G><H><V><T><P><I><M><Q><L><G><K><A><L><Y><S><K><G><F><S><I><T><V><V><L><T><Q><Y><N><R><V><S><S><S><K><D><F><S><D><F><H><F><L><T><I><P><G><S><L><T><E><S><D><L><K><N><L><G><P><F><K><F><L><F><K><L><N><Q><I><C><E><A><S><F><K><Q><C><I><G><Q><L><L><Q><E><Q><G><N><D><I><A... | Possesses low quercetin 3-O-glucosyltransferase and 7-O-glucosyltransferase activities in vitro.<BOP> | Q9LTH3 |
P01900 | HA12_MOUSE | H-2 class I histocompatibility antigen, D-D alpha chain | Mus | <M><G><A><M><A><P><R><T><L><L><L><L><L><A><A><A><L><G><P><T><Q><T><R><A><G><S><H><S><L><R><Y><F><V><T><A><V><S><R><P><G><F><G><E><P><R><Y><M><E><V><G><Y><V><D><N><T><E><F><V><R><F><D><S><D><A><E><N><P><R><Y><E><P><R><A><R><W><I><E><Q><E><G><P><E><Y><W><E><R><E><T><R><R><A><K><G><N><E><Q><S><F><R><V><D><L><R><T><A><L><R... | Involved in the presentation of foreign antigens to the immune system.<BOP> | P01900 |
O79436 | NU4M_RABIT | NADH dehydrogenase subunit 4 | Oryctolagus | <M><L><K><T><I><I><P><T><I><M><L><I><P><T><V><W><W><S><K><P><H><M><I><W><I><N><A><T><V><Y><S><L><L><I><S><L><T><T><L><S><L><L><N><Q><P><S><D><T><N><L><N><F><S><T><T><F><F><S><D><A><L><S><T><P><L><L><M><L><T><T><W><L><L><P><L><M><I><L><A><S><Q><H><H><L><D><K><E><T><L><T><R><K><K><I><Y><I><S><L><L><I><S><L><Q><V><F><L><V... | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.<BOP> | O79436 |
Q6AX58 | PHIPL_XENLA | Phytanoyl-CoA hydroxylase-interacting protein-like | Xenopus | <M><E><V><P><R><L><S><Q><H><M><S><T><P><N><S><P><C><E><E><M><I><K><N><L><S><L><E><N><I><Q><L><C><E><R><D><G><N><K><S><Q><D><S><G><I><A><E><M><E><E><L><P><V><P><H><N><I><K><I><S><N><I><T><C><D><S><F><K><I><S><W><D><M><D><P><K><S><K><D><R><I><T><H><Y><F><V><D><L><N><K><K><E><N><K><N><S><N><K><F><K><H><K><D><V><P><T><K><L... | May play a role in the development of the central system.<BOP> | Q6AX58 |
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