accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q8CPM1 | COXX_STAES | Heme O synthase | Staphylococcus | <M><N><K><D><Q><T><L><S><H><T><T><G><R><V><S><F><K><E><L><Q><Q><I><I><K><M><G><L><V><Q><G><N><L><I><P><A><F><A><G><A><W><L><A><I><V><M><T><N><H><S><F><L><S><S><I><P><Q><I><L><L><M><L><V><G><S><T><L><I><M><G><G><A><C><A><L><N><N><Y><Y><D><Q><D><I><D><R><I><M><P><S><K><Q><G><R><P><T><V><N><D><R><I><S><D><R><N><L><L><M><L... | Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.<BOP> | Q8CPM1 |
Q9UWW8 | VATB_SACS2 | V-ATPase subunit B | Saccharolobus | <M><L><S><V><R><E><F><S><N><I><S><M><I><K><G><P><L><V><Y><V><Q><G><V><T><D><A><S><Y><N><E><L><V><E><I><E><M><P><N><G><E><R><R><R><G><L><V><I><D><S><Q><M><G><I><A><I><V><Q><V><F><E><G><T><T><G><V><S><P><T><G><T><K><I><R><M><L><G><R><G><L><E><V><K><I><S><E><E><M><L><G><R><I><F><N><P><L><G><D><S><L><D><N><G><P><P><V><I><K... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.<BOP> | Q9UWW8 |
C1DFV8 | DEF_AZOVD | Polypeptide deformylase | Azotobacter | <M><A><I><L><T><I><L><E><F><P><D><P><R><L><R><T><I><A><K><P><I><E><T><V><D><D><G><I><R><R><L><I><D><D><M><F><E><T><M><Y><A><A><P><G><I><G><L><A><A><T><Q><V><N><V><H><K><R><L><V><V><M><D><L><S><E><D><K><N><E><P><R><V><F><I><N><P><E><F><E><A><L><T><E><E><L><E><P><Y><Q><E><G><C><L><S><V><P><G><F><Y><E><N><V><D><R><P><Q><K... | Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.<BOP> | C1DFV8 |
A6W5U4 | RS3_KINRD | 30S ribosomal protein S3 | Kineococcus | <M><G><Q><K><V><N><P><F><G><F><R><L><G><I><T><T><D><H><R><S><R><W><F><A><D><S><T><K><T><G><Q><R><Y><A><D><Y><V><K><E><D><V><A><I><R><R><L><M><S><K><G><M><E><R><A><G><I><S><K><V><E><I><E><R><T><R><D><R><V><R><V><D><I><H><T><A><R><P><G><I><V><I><G><R><R><G><A><E><A><D><R><I><R><T><E><L><E><K><L><T><G><K><Q><V><Q><L><N><I... | Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.<BOP> | A6W5U4 |
Q9ZDT4 | PSD_RICPR | Phosphatidylserine decarboxylase beta chain | typhus group | <M><K><Q><Y><N><D><L><F><K><I><I><H><R><E><G><Y><I><F><I><A><S><F><A><L><V><S><F><L><L><A><S><F><N><E><K><L><G><C><I><G><F><I><A><T><I><W><C><I><Y><F><F><R><N><P><D><R><F><V><P><I><S><D><D><L><V><I><S><P><A><D><G><I><I><Q><E><I><K><E><A><S><P><P><P><E><L><G><L><G><D><L><E><M><I><R><V><S><I><F><L><N><I><F><N><I><H><V><N... | Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).<BOP> | Q9ZDT4 |
Q9XLE1 | CYB_REDFU | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Redunca | <M><T><N><I><R><K><T><H><P><L><M><K><I><V><N><N><A><F><I><D><L><P><A><P><S><N><I><S><S><W><W><N><F><G><S><L><L><G><I><C><L><M><L><Q><I><L><T><G><L><F><L><A><M><H><Y><T><S><D><T><A><T><A><F><S><S><V><T><H><I><C><R><D><V><N><Y><G><W><I><I><R><Y><M><H><A><N><G><A><S><M><F><F><I><C><L><F><M><H><V><G><R><G><L><Y><Y><G><S><Y... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | Q9XLE1 |
B6HRA4 | SDHF2_PENRW | Succinate dehydrogenase assembly factor 2, mitochondrial | Penicillium chrysogenum species complex | <M><S><A><P><R><I><L><H><R><V><A><R><P><V><P><S><S><I><S><T><I><T><R><L><N><R><Q><F><G><T><T><A><L><R><L><K><D><G><S><D><E><A><S><P><E><V><K><A><H><R><A><N><Q><A><N><K><A><P><N><Q><F><V><P><N><T><T><S><T><M><T><K><D><F><V><N><V><G><Q><K><P><A><P><P><E><M><L><N><S><A><N><P><N><Y><R><P><S><D><P><Y><P><G><R><I><E><H><F><T... | Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduct... | B6HRA4 |
P58793 | PURA_FUSNN | IMP--aspartate ligase | Fusobacterium | <M><A><G><Y><V><V><V><G><T><Q><W><G><D><E><G><K><G><K><I><I><D><V><L><S><E><K><A><D><Y><V><V><R><F><Q><G><G><N><N><A><G><H><T><V><V><V><D><G><E><K><F><I><L><Q><L><L><P><S><G><V><L><Q><A><G><T><C><V><I><G><P><G><V><V><I><D><P><K><V><F><L><D><E><I><D><R><I><E><K><R><G><A><K><T><D><H><V><I><I><S><D><R><A><H><V><I><M><P><Y... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP> | P58793 |
B9DNH1 | YQGF_STACT | Putative pre-16S rRNA nuclease | Staphylococcus | <M><L><T><H><K><I><I><G><L><D><V><G><S><K><T><V><G><V><A><V><S><D><L><M><G><W><T><A><Q><G><L><D><T><L><R><I><N><E><E><E><N><E><L><G><I><T><K><L><A><E><I><I><K><K><E><D><A><D><T><V><V><I><G><L><P><K><N><M><N><N><S><I><G><F><R><G><E><A><S><L><K><Y><K><E><E><L><L><K><I><L><P><D><I><N><V><V><M><W><D><E><R><L><S><T><M><A><A... | Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP> | B9DNH1 |
Q2V3I3 | EPFL4_ARATH | CHALLAH-LIKE2 | Arabidopsis | <M><G><T><F><R><R><R><R><R><F><L><L><A><A><L><V><T><F><A><L><L><H><L><F><S><A><S><S><I><V><S><A><D><G><R><W><I><G><Q><R><T><G><S><D><L><P><G><G><F><I><R><S><N><K><R><F><G><G><P><G><S><S><P><P><T><C><R><S><K><C><G><K><C><Q><P><C><K><P><V><H><V><P><I><Q><P><G><L><S><M><P><L><E><Y><Y><P><E><A><W><R><C><K><C><G><N><K><L><F... | Acts primarily as positive regulator of inflorescence growth. Endodermal expression is sufficient for proper inflorescence architecture . Redundantly involved with EPFL6 in procambial development regulation. Controls stomatal patterning. Mediates stomatal development inhibition. TMM (AC Q9SSD1) functions to dampen or b... | Q2V3I3 |
A1SA65 | PURA_SHEAM | IMP--aspartate ligase | Shewanella | <M><G><K><N><V><V><V><L><G><T><Q><W><G><D><E><G><K><G><K><I><V><D><L><L><T><E><Q><A><K><Y><V><V><R><Y><Q><G><G><H><N><A><G><H><T><L><V><I><D><G><V><K><T><V><L><H><L><I><P><S><G><I><L><R><D><N><V><K><C><I><I><G><N><G><V><V><L><A><P><D><A><L><M><K><E><I><S><M><L><K><E><R><G><V><P><V><E><D><R><L><L><I><S><E><A><C><P><L><I... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP> | A1SA65 |
Q2W548 | COXX2_MAGSA | Heme O synthase 2 | Magnetospirillum | <M><T><A><N><L><K><V><L><A><S><V><F><K><L><R><I><G><V><F><C><A><L><A><A><I><A><G><A><L><A><T><P><G><A><V><P><D><F><A><P><V><M><A><V><A><L><A><V><L><L><S><A><A><A><A><G><A><F><N><H><Y><W><E><R><D><I><D><P><M><M><N><R><T><R><N><R><P><F><A><T><G><Q><F><A><A><G><P><L><W><P><L><G><L><L><A><L><T><V><A><A><V><A><L><A><A><F><A... | Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.<BOP> | Q2W548 |
Q6CMK7 | SLD1_KLULA | Delta 8-(E)-sphingolipid desaturase | Kluyveromyces | <M><S><R><V><L><S><R><R><D><I><A><D><R><I><A><K><G><Q><T><I><V><I><Y><E><D><S><V><L><N><L><D><K><W><I><K><F><H><P><G><G><D><K><S><I><Y><H><M><I><G><R><D><A><T><D><E><M><N><A><Y><H><D><D><Q><T><I><T><K><F><K><I><W><K><I><G><R><I><D><Y><P><W><E><N><M><L><P><P><I><Q><G><G><R><F><S><K><I><D><E><R><D><D><I><G><D><Y><D><I><N... | Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.<BOP> | Q6CMK7 |
B3H6D0 | HIP45_ARATH | Heavy metal-associated isoprenylated plant protein 45 | Arabidopsis | <M><F><D><W><I><H><G><N><S><R><L><P><I><A><L><S><I><V><E><L><L><V><D><M><D><C><K><G><C><E><K><K><V><R><R><A><I><S><K><L><D><G><V><D><T><V><E><I><D><V><D><R><Q><K><V><T><V><T><G><Y><V><D><R><E><E><V><L><K><M><V><K><R><T><G><R><T><A><E><Y><W><P><F><P><Y><N><G><Y><Y><G><D><Y><Y><T><Y><P><S><Q><H><L><E><Q><S><D><Q><K><I><Y... | Heavy-metal-binding protein.<BOP> | B3H6D0 |
A5D9W7 | MCA1_PICGU | Metacaspase-1 | Meyerozyma | <M><F><P><G><S><G><R><Q><T><Y><Q><Q><Q><G><Y><P><P><P><Q><G><A><P><Q><Y><N><Y><G><P><P><Q><G><P><P><Q><G><Y><Y><N><G><P><P><Q><G><Y><N><G><P><P><Q><G><P><P><P><Q><N><Y><N><Y><G><H><Y><G><P><P><Q><G><Q><G><Q><G><Y><G><Q><G><G><P><A><P><Q><M><Y><N><N><N><R><Q><S><G><A><M><N><D><V><S><T><A><P><Q><R><F><G><N><T><D><M><T><Y... | Involved in cell death (apoptosis).<BOP> | A5D9W7 |
Q3Z2G2 | MNTP_SHISS | Probable manganese efflux pump MntP | Shigella | <M><N><I><T><A><T><V><L><L><A><F><G><M><S><M><D><A><F><A><A><S><V><G><K><G><A><T><L><H><K><P><K><F><S><E><A><L><R><T><G><L><I><F><G><A><V><E><T><L><T><P><L><I><G><W><G><M><G><M><L><A><S><R><F><V><L><E><W><N><H><W><I><A><F><V><L><L><I><F><L><G><G><R><M><I><I><E><G><F><R><G><A><D><D><E><D><E><E><P><R><R><R><H><G><F><W><L... | Probably functions as a manganese efflux pump.<BOP> | Q3Z2G2 |
Q2LWT5 | DUT_SYNAS | dUTP pyrophosphatase | Syntrophus | <M><T><G><I><R><I><S><V><Q><T><L><P><H><F><E><G><L><S><L><P><R><Y><M><S><E><H><A><A><G><M><D><I><C><A><A><V><A><D><E><V><V><I><L><P><G><E><R><A><L><I><P><T><G><I><A><I><A><L><P><E><G><F><E><A><Q><I><R><P><R><S><G><L><A><L><K><H><G><V><T><L><V><N><A><P><G><T><I><D><A><D><Y><R><G><E><I><G><V><L><L><I><N><H><G><N><D><P><F... | This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.<BOP> | Q2LWT5 |
O48109 | CYB_PYTRG | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Python | <M><P><H><H><Y><I><L><T><L><F><G><L><L><P><V><A><T><N><I><S><T><W><W><N><F><G><S><M><L><L><T><C><L><M><L><Q><V><L><T><G><F><F><L><A><V><H><Y><T><A><N><I><N><L><A><F><S><S><I><I><H><I><T><R><D><V><P><Y><G><W><L><M><Q><N><L><H><A><I><G><A><S><M><F><F><I><C><I><Y><I><H><I><A><R><G><L><Y><Y><G><S><H><L><N><K><E><T><W><M><S... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | O48109 |
Q6X4A2 | CIPKV_ORYSJ | OsCIPK31 | Oryza sativa | <M><Y><R><A><K><R><A><A><L><S><P><K><V><K><R><R><V><G><K><Y><E><L><G><R><T><I><G><E><G><T><F><A><K><V><R><F><A><K><N><T><E><N><D><E><P><V><A><I><K><I><L><D><K><E><K><V><Q><K><H><R><L><V><E><Q><I><R><R><E><I><C><T><M><K><L><V><K><H><P><N><V><V><R><L><F><E><V><M><G><S><K><A><R><I><F><I><V><L><E><Y><V><T><G><G><E><L><F><E... | Involved in cold stress tolerance. CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner.<BOP> | Q6X4A2 |
Q0SXQ7 | UBIA_SHIF8 | 4-HB polyprenyltransferase | Shigella | <M><E><W><S><L><T><Q><N><K><L><L><A><F><H><R><L><M><R><T><D><K><P><I><G><A><L><L><L><L><W><P><T><L><W><A><L><W><V><A><T><P><G><V><P><Q><L><W><I><L><A><V><F><V><A><G><V><W><L><M><R><A><A><G><C><V><V><N><D><Y><A><D><R><K><F><D><G><H><V><K><R><T><A><N><R><P><L><P><S><G><A><V><T><E><K><E><A><R><A><L><F><V><V><L><V><L><I><S... | Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-... | Q0SXQ7 |
Q6MC72 | AMPA_PARUW | Leucyl aminopeptidase | Candidatus Protochlamydia | <M><E><F><A><L><T><L><H><I><E><K><R><K><K><A><D><V><L><V><L><P><F><W><K><G><T><S><Q><P><E><A><A><I><A><L><H><P><L><K><L><S><L><D><S><V><F><N><T><G><D><F><K><G><K><E><G><E><T><L><F><L><Y><V><E><G><L><V><E><M><R><V><A><L><L><G><L><G><E><K><N><K><V><S><T><E><A><L><R><K><S><Y><G><C><L><A><K><A><C><L><G><K><K><L><K><T><L><N... | Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.<BOP> | Q6MC72 |
B1JT65 | RIMO_BURCC | Ribosome maturation factor RimO | Burkholderia cepacia complex | <M><S><Q><S><P><K><V><G><F><V><S><L><G><C><P><K><A><L><V><D><S><E><Q><I><I><T><Q><L><R><A><E><G><Y><E><I><S><G><S><Y><D><G><A><D><L><V><V><V><N><T><C><G><F><I><D><E><A><V><Q><E><S><L><D><A><I><G><E><A><L><T><E><N><G><K><V><I><V><T><G><C><L><G><A><K><S><S><A><S><G><S><N><L><I><E><E><V><H><P><K><V><L><A><V><T><G><P><H><A... | Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.<BOP> | B1JT65 |
Q8RGE1 | ATPG_FUSNN | F-ATPase gamma subunit | Fusobacterium | <M><P><G><M><K><E><I><K><S><R><I><K><S><V><Q><S><T><R><Q><I><T><N><A><M><E><I><V><S><T><T><K><F><K><R><Y><S><K><L><V><T><E><S><R><P><Y><E><E><S><M><R><K><I><L><G><N><I><A><S><G><V><K><N><E><G><H><P><L><F><D><G><R><K><E><V><K><S><I><A><I><I><V><I><T><S><D><R><G><L><C><G><S><F><N><S><S><T><L><K><E><L><E><K><L><V><E><K><N... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP> | Q8RGE1 |
Q9Y3Y2 | CHTOP_HUMAN | Small arginine- and glycine-rich protein | Homo | <M><A><A><Q><S><A><P><K><V><V><L><K><S><T><T><K><M><S><L><N><E><R><F><T><N><M><L><K><N><K><Q><P><T><P><V><N><I><R><A><S><M><Q><Q><Q><Q><Q><L><A><S><A><R><N><R><R><L><A><Q><Q><M><E><N><R><P><S><V><Q><A><A><L><K><L><K><Q><S><L><K><Q><R><L><G><K><S><N><I><Q><A><R><L><G><R><P><I><G><A><L><A><R><G><A><I><G><G><R><G><L><P><I... | Required for effective mRNA nuclear export and is a component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, bind... | Q9Y3Y2 |
Q471H6 | HUTG_CUPPJ | Formiminoglutamate hydrolase | Cupriavidus | <M><R><M><A><V><T><Q><N><P><W><Q><G><R><V><D><S><G><E><V><G><D><T><T><R><L><F><R><I><V><N><T><L><E><S><S><E><A><K><T><L><G><G><S><P><V><L><L><G><F><G><C><D><A><G><V><L><R><N><Q><G><R><A><G><A><A><H><G><P><D><A><I><R><Q><A><L><A><N><V><P><A><H><G><L><P><A><L><Y><D><A><G><N><I><A><C><E><H><G><D><L><E><S><A><Q><L><A><L><A... | Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.<BOP> | Q471H6 |
B8J823 | SYT_ANAD2 | Threonyl-tRNA synthetase | Anaeromyxobacter | <M><S><D><L><V><K><V><T><L><P><D><G><S><Q><K><E><A><P><R><G><T><P><V><I><D><F><V><K><G><Q><I><G><P><G><L><A><K><A><A><Y><F><A><R><L><D><G><E><P><V><D><L><S><R><A><I><E><R><D><A><R><L><E><I><V><T><T><R><N><P><E><A><L><E><V><A><R><H><D><A><A><H><V><M><A><S><V><V><Q><K><L><Y><P><G><T><Q><V><T><I><G><P><A><I><E><D><G><F><Y... | Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).<BOP> | B8J823 |
A6SX19 | EFP_JANMA | Elongation factor P | Janthinobacterium | <M><K><P><A><K><E><I><R><V><G><N><I><I><M><V><D><S><K><P><M><I><V><L><R><S><D><V><N><G><S><S><R><T><G><F><T><Y><K><W><K><M><K><N><L><L><T><N><T><P><M><E><N><V><F><R><G><D><D><K><F><D><V><V><V><L><D><K><K><P><V><T><Y><S><Y><F><A><D><P><L><Y><V><F><M><D><E><E><Y><N><Q><Y><E><I><E><E><E><N><L><G><D><A><L><H><Y><L><K><D><G... | Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP> | A6SX19 |
A9M0D4 | RUVC_NEIM0 | Holliday junction resolvase RuvC | Neisseria | <M><A><A><S><V><R><I><L><G><I><D><P><G><S><R><V><T><G><F><G><V><I><D><V><R><G><R><D><H><F><Y><V><A><S><G><C><I><K><T><P><A><D><A><P><L><A><D><R><I><A><V><I><V><R><H><I><G><E><V><V><A><V><Y><K><P><Q><Q><A><A><V><E><Q><V><F><V><N><V><N><P><A><S><T><L><M><L><G><Q><A><R><G><A><A><L><A><A><L><V><S><H><K><L><P><V><S><E><Y><T... | Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.<BOP> | A9M0D4 |
Q9QZL9 | DKKL1_MOUSE | Protein soggy-1 | Mus | <M><C><R><L><R><V><L><L><L><L><L><P><L><A><F><V><S><S><S><A><L><P><I><H><D><V><D><S><Q><Q><N><T><S><G><F><L><G><L><Q><R><L><L><Q><S><F><S><R><L><F><L><K><N><D><L><L><R><D><L><D><N><F><F><S><S><P><M><D><F><R><D><L><P><R><N><F><H><Q><E><E><N><Q><E><H><R><M><G><N><H><T><L><S><S><H><L><Q><I><D><K><V><T><D><N><Q><T><G><E><V... | Involved in fertilization by facilitating sperm penetration of the zona pellucida . May promote spermatocyte apoptosis, thereby limiting sperm production. In adults, may reduce testosterone synthesis in Leydig cells . Is not essential either for development or fertility .<BOP> | Q9QZL9 |
Q7WI95 | IXTPA_BORBR | Nucleoside-triphosphate pyrophosphatase | Bordetella | <M><S><A><E><I><L><N><P><N><L><R><R><V><V><L><A><S><N><N><A><G><K><L><R><E><F><S><A><L><F><A><P><L><G><I><E><L><V><P><Q><S><E><L><G><V><S><E><A><E><E><P><H><A><T><F><V><E><N><A><L><A><K><A><R><H><A><S><R><H><T><G><L><P><A><L><A><D><D><S><G><L><C><V><V><A><L><G><G><A><P><G><V><H><S><A><R><Y><A><Q><Q><P><G><G><A><R><S><D... | Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical p... | Q7WI95 |
Q1QDK7 | SYP_PSYCK | Prolyl-tRNA synthetase | Psychrobacter | <M><K><A><S><Q><F><L><F><A><T><L><K><E><T><P><S><D><A><D><I><A><S><S><Q><L><M><V><R><A><G><L><I><R><K><I><A><S><G><L><Y><I><W><L><P><M><G><L><R><V><L><Q><K><V><E><R><I><V><R><E><E><M><Q><N><I><G><A><Q><E><V><L><M><P><M><T><Q><P><A><E><L><W><Q><L><T><G><R><F><N><D><Y><G><P><E><L><L><R><F><K><D><R><H><D><R><D><F><V><L><G... | Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two addit... | Q1QDK7 |
P62590 | INT2_ECOLX | E2 protein | Escherichia | <M><K><T><A><T><A><P><L><P><P><L><R><S><V><K><V><L><D><Q><L><R><E><R><I><R><Y><L><H><Y><S><L><R><T><E><Q><A><Y><V><H><W><V><R><A><F><I><R><F><H><G><V><R><H><P><A><T><L><G><S><S><E><V><E><A><F><L><S><W><L><A><N><E><R><K><V><S><V><S><T><H><R><Q><A><L><A><A><L><L><F><F><Y><G><K><V><L><C><T><D><L><P><W><L><Q><E><I><G><R><P... | Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons.<BOP> | P62590 |
E3PQQ8 | CCAP_CONVL | ConoCAP-c | Dauciconus | <M><V><S><L><G><H><V><L><F><V><I><L><L><P><V><L><L><P><V><A><A><D><D><P><D><D><Q><M><L><S><Q><I><S><L><P><S><S><S><R><S><E><Y><D><D><N><D><V><S><K><R><V><F><C><N><G><F><T><G><C><G><G><R><H><R><D><R><S><R><R><Q><E><R><Y><G><K><R><L><I><P><V><L><A><K><R><P><F><C><N><S><F><G><C><Y><N><G><K><R><S><L><S><G><A><G><P><A><L><S... | Synthetic conoCAP-c decreases the heart frequency of 12% in Drosophila larvae.<BOP> | E3PQQ8 |
Q8LPS1 | LACS6_ARATH | Long chain acyl-CoA synthetase 6, peroxisomal | Arabidopsis | <M><D><S><S><S><S><S><S><S><A><A><A><R><R><R><I><N><A><I><H><S><H><L><V><T><S><S><R><S><S><P><L><L><R><S><N><P><T><A><G><E><F><C><L><D><N><G><Y><S><V><V><L><P><E><K><L><N><T><G><S><W><N><V><Y><R><S><A><K><S><P><F><K><L><V><S><R><F><P><D><H><P><D><I><A><T><L><H><D><N><F><E><H><A><V><H><D><F><R><D><Y><K><Y><L><G><T><R><V... | Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation (Probable). Preferentially uses palmitate, palmitoleate, oleate, linoleate and eicosenoate as substrates . Can use myristate and linolenate as substrates . May play a regulatory role both in fatty acid import ... | Q8LPS1 |
Q6MPX9 | MACB_BDEBA | Macrolide export ATP-binding/permease protein MacB | Bdellovibrio | <M><I><D><I><K><G><I><R><K><S><Y><Q><M><G><D><T><K><V><D><V><L><K><G><I><S><L><K><I><E><R><G><D><F><V><A><I><M><G><P><S><G><S><G><K><S><T><L><M><H><I><L><G><L><L><D><V><P><S><E><G><S><Y><N><L><N><G><R><E><V><A><D><L><S><E><D><E><L><A><I><V><R><R><E><E><I><G><F><I><F><Q><Q><F><N><L><L><P><R><M><E><A><W><Q><N><V><S><L><P... | Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.<BOP> | Q6MPX9 |
A8ESU8 | RL22_ALIB4 | 50S ribosomal protein L22 | Aliarcobacter | <M><A><K><A><I><L><K><F><I><R><V><S><P><I><K><A><R><L><I><A><R><E><V><Q><G><M><N><A><E><Y><A><I><A><S><L><Q><F><T><P><N><K><A><A><G><I><I><S><K><V><I><A><S><A><V><A><N><A><G><L><D><P><V><D><A><V><I><T><S><A><R><V><D><K><G><P><V><L><K><R><F><T><P><R><A><R><G><S><A><S><P><K><H><K><P><T><A><H><I><M><I><E><V><A><A><A><T><K... | The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.<BOP> | A8ESU8 |
Q2S919 | RL16_HAHCH | 50S ribosomal protein L16 | Hahella | <M><L><Q><P><K><R><T><K><F><R><K><V><H><K><G><R><N><T><G><L><A><Q><R><G><N><K><V><S><F><G><E><F><G><L><K><A><T><G><R><G><R><I><T><A><R><Q><I><E><A><A><R><R><T><M><T><R><R><I><K><R><G><G><K><I><W><I><R><I><F><P><D><K><P><I><T><K><K><P><L><E><V><R><M><G><K><G><K><G><P><V><E><Y><W><V><A><E><I><E><P><G><R><M><L><Y><E><M><E... | Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP> | Q2S919 |
Q4AAV4 | OBG_MESHJ | GTP-binding protein Obg | Mesomycoplasma | <M><R><F><V><D><Y><V><S><I><E><V><V><A><G><K><G><G><D><G><I><I><S><F><R><R><E><A><H><V><D><K><G><G><P><D><G><G><D><G><G><W><G><G><S><I><Y><F><V><G><D><S><G><M><N><T><L><L><P><F><Y><Q><T><K><K><I><F><G><Y><N><G><E><N><G><R><P><K><R><Q><T><G><A><N><G><K><D><I><F><I><K><V><P><L><G><T><Q><V><F><L><K><K><S><L><I><C><D><I><I... | An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B... | Q4AAV4 |
P49765 | VEGFB_HUMAN | VEGF-related factor | Homo | <M><S><P><L><L><R><R><L><L><L><A><A><L><L><Q><L><A><P><A><Q><A><P><V><S><Q><P><D><A><P><G><H><Q><R><K><V><V><S><W><I><D><V><Y><T><R><A><T><C><Q><P><R><E><V><V><V><P><L><T><V><E><L><M><G><T><V><A><K><Q><L><V><P><S><C><V><T><V><Q><R><C><G><G><C><C><P><D><D><G><L><E><C><V><P><T><G><Q><H><Q><V><R><M><Q><I><L><M><I><R><Y><P... | Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.<BOP> | P49765 |
A7FLI9 | DPO4_YERP3 | DNA polymerase IV | Yersinia | <M><R><K><I><I><H><V><D><M><D><C><F><F><A><A><V><E><M><R><D><D><P><R><L><R><D><I><P><L><A><I><G><G><S><K><E><R><R><G><V><I><S><T><A><N><Y><P><A><R><R><Y><G><V><R><S><A><M><P><T><A><M><A><F><K><L><C><P><Q><L><T><L><L><P><G><R><M><A><A><Y><K><E><A><S><Q><H><I><R><E><I><F><A><R><Y><T><P><L><I><E><P><L><S><L><D><E><A><Y><L... | Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in... | A7FLI9 |
Q9AP06 | KATG_BURCE | Peroxidase/catalase | Burkholderia cepacia complex | <M><S><N><E><G><Q><C><P><F><N><H><A><N><G><G><G><T><T><N><R><D><W><W><P><N><E><L><R><L><D><L><L><S><Q><H><S><S><K><T><D><P><L><D><P><G><F><N><Y><A><E><A><F><N><S><L><D><L><D><A><L><R><K><D><L><A><A><L><M><T><D><S><Q><D><W><W><P><A><D><F><G><H><Y><G><P><L><F><V><R><M><A><W><H><S><A><G><T><Y><R><M><G><D><G><R><G><G><A><G... | Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. Required for maintaining the normal activity of the TCA cycle.<BOP> | Q9AP06 |
Q07V79 | RBFA_RHOP5 | Ribosome-binding factor A | Rhodopseudomonas | <M><P><R><H><H><Q><K><N><S><G><R><E><A><S><Q><R><Q><L><R><V><G><E><S><V><R><H><A><I><A><E><I><L><A><Q><G><G><V><H><D><P><V><L><E><G><H><L><V><T><V><P><E><V><R><M><S><P><D><L><K><L><A><T><I><Y><V><M><P><L><G><G><R><D><T><E><L><V><L><K><A><L><D><H><N><K><K><F><L><R><G><E><V><S><R><R><V><N><L><K><F><A><P><E><L><R><F><R><A... | One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli... | Q07V79 |
Q03614 | NTDO_CAEEL | Sodium-dependent dopamine transporter | Caenorhabditis | <M><Q><L><V><P><T><D><D><P><D><E><K><I><G><R><T><S><N><G><M><Q><N><A><T><L><P><I><D><G><P><V><N><T><E><P><K><D><P><A><R><E><Q><W><S><G><K><L><D><F><L><L><S><V><V><G><F><A><V><D><L><G><N><I><W><R><F><P><Y><L><C><F><K><N><G><G><G><V><F><L><I><P><Y><S><I><M><V><L><L><T><G><V><P><L><F><Y><M><E><L><C><L><G><Q><Y><Y><R><K><G... | Dopamine transporter . Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.<BOP> | Q03614 |
P69929 | TX9A_ANTMC | Peptide toxins Am-1 | Antheopsis | <M><K><R><I><F><I><V><A><L><L><F><A><T><C><L><V><N><A><K><P><S><I><N><D><A><D><I><K><R><E><P><E><P><N><V><A><V><P><P><C><G><D><C><Y><Q><Q><V><G><N><T><C><V><R><V><P><S><L><C><P><S><R><K><R><E><P><E><P><N><V><A><V><P><P><C><G><D><C><Y><Q><Q><V><G><N><T><C><V><R><V><P><S><L><C><P><S><R><K><R><E><P><E><P><N><V><A><V><P><P... | May inhibit voltage-gated sodium channels (Nav).<BOP> | P69929 |
B0C0B6 | RECO_ACAM1 | Recombination protein O | Acaryochloris | <M><S><R><T><Y><K><A><T><G><I><N><L><K><S><M><P><F><G><E><A><D><R><L><L><T><I><L><T><R><E><Q><G><L><V><R><A><V><A><P><G><C><R><K><P><K><S><K><L><G><G><R><S><A><L><F><V><V><N><D><L><M><L><V><Q><G><R><S><L><D><K><I><A><Q><A><E><T><L><E><S><Y><P><G><L><S><Q><N><L><A><K><L><T><T><S><Q><Y><L><A><E><L><T><L><Y><Q><A><L><S><G... | Involved in DNA repair and RecF pathway recombination.<BOP> | B0C0B6 |
B1YLP7 | EFP_EXIS2 | Elongation factor P | Exiguobacterium | <M><V><S><V><N><D><L><K><T><G><L><T><I><K><T><S><D><G><M><I><W><Q><V><L><E><F><Q><H><V><K><P><G><K><G><A><A><F><V><R><T><K><M><R><N><I><R><N><G><N><I><Q><E><M><T><F><R><G><G><E><R><V><E><R><A><H><I><E><R><N><K><M><Q><Y><L><Y><P><M><G><E><T><Y><V><F><M><D><T><E><S><Y><E><Q><L><E><L><T><T><A><Q><V><E><A><A><L><P><F><L><L... | Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP> | B1YLP7 |
Q73X85 | MURI_MYCPA | Glutamate racemase | Mycobacterium avium complex (MAC) | <M><S><S><A><L><A><P><V><G><I><F><D><S><G><V><G><G><L><T><V><A><R><A><I><I><D><Q><L><P><D><E><H><I><I><Y><V><G><D><T><G><H><G><P><Y><G><P><L><S><I><P><E><V><R><A><H><A><L><A><I><G><D><D><L><V><G><R><G><V><K><A><L><V><I><A><C><N><T><A><S><A><A><C><L><R><D><A><R><E><R><Y><E><V><P><V><V><E><V><I><L><P><A><V><R><R><A><V><A... | Provides the (R)-glutamate required for cell wall biosynthesis.<BOP> | Q73X85 |
Q0HKG4 | G1091_SHESM | Glycosyl hydrolase family 109 protein 1 | Shewanella | <M><H><N><I><H><R><R><H><F><L><K><A><A><G><A><V><T><A><G><L><V><T><A><N><I><A><L><N><A><N><A><S><S><V><A><P><K><P><R><V><G><K><S><V><I><G><L><I><A><P><K><M><E><L><V><R><V><G><F><I><G><V><G><E><R><G><F><S><H><V><E><Q><F><C><H><L><E><G><V><E><L><K><A><I><C><D><T><H><Q><A><V><I><D><R><A><V><E><H><I><V><N><Q><N><R><P><K><P... | Glycosidase.<BOP> | Q0HKG4 |
Q08219 | RRT8_YEAST | Regulator of rDNA transcription protein 8 | Saccharomyces | <M><K><A><G><I><E><L><I><S><H><S><Q><A><S><H><A><T><Y><A><N><S><M><T><L><A><E><K><G><P><Q><R><L><K><R><Q><F><K><E><H><S><S><S><K><E><S><N><V><S><R><W><L><K><I><F><I><R><Q><F><D><I><W><F><P><E><T><I><P><T><M><K><V><R><Y><E><L><L><R><K><N><F><I><K><E><I><F><N><S><R><A><F><I><Y><P><F><L><G><F><Y><E><V><L><T><N><P><V><Y><W... | Involved in spore wall assembly . May be involved in the modulation of rDNA transcription .<BOP> | Q08219 |
Q5L5D3 | ISPH_CHLAB | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | Chlamydia | <M><R><R><V><I><L><S><N><P><R><G><F><C><A><G><V><V><R><A><I><Q><V><V><E><S><A><L><E><K><W><G><A><P><I><Y><V><K><H><E><I><V><H><N><R><H><V><V><D><D><L><K><R><R><G><A><I><F><I><E><D><L><K><D><V><P><C><G><E><K><V><I><Y><S><A><H><G><I><P><P><E><V><R><E><E><A><K><A><R><N><L><F><D><I><D><A><T><C><V><L><V><T><K><I><H><S><A><V... | Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.<BOP> | Q5L5D3 |
Q31NM6 | SYDND_SYNE7 | Non-discriminating aspartyl-tRNA synthetase | Synechococcus | <M><R><T><H><Y><C><G><E><L><R><A><E><Q><V><G><T><S><V><T><L><Y><G><W><V><D><R><R><R><D><H><G><G><V><I><F><V><D><L><R><D><R><T><G><T><V><Q><I><V><S><D><P><E><R><T><P><E><S><Y><H><Q><A><E><G><L><R><N><E><Y><V><V><K><I><T><G><R><V><S><G><R><P><A><E><S><L><N><P><K><L><P><T><G><E><V><E><I><Y><A><D><R><I><E><I><L><N><A><V><R... | Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).<BOP> | Q31NM6 |
A3N1D8 | ORN_ACTP2 | Oligoribonuclease | Actinobacillus | <M><S><K><L><D><N><Q><N><L><I><W><I><D><L><E><M><T><G><L><D><P><E><K><E><R><I><I><E><V><A><T><I><V><T><D><K><D><L><N><I><L><A><E><G><P><V><L><T><V><H><Q><S><N><D><L><L><N><K><M><S><D><W><C><I><K><T><H><T><E><N><G><L><I><E><R><V><K><Q><S><K><L><T><E><R><A><V><E><L><Q><T><I><D><F><L><K><Q><W><V><P><K><G><A><S><P><I><C><G... | 3'-to-5' exoribonuclease specific for small oligoribonucleotides.<BOP> | A3N1D8 |
Q5SD05 | ATPE_HUPLU | F-ATPase epsilon subunit | Huperzia | <M><T><L><N><L><R><V><M><T><P><N><R><T><V><W><N><S><E><V><Q><E><M><I><L><S><T><N><S><G><Q><I><G><V><L><P><N><H><A><P><L><L><T><A><L><D><I><G><I><T><K><I><R><L><N><G><Q><W><S><T><M><A><L><M><G><G><F><A><M><V><D><N><N><Q><V><T><I><L><V><N><E><A><E><E><A><A><G><I><D><P><Q><E><A><K><E><T><F><R><I><A><Q><T><N><L><A><R><A><E... | Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP> | Q5SD05 |
P00919 | CAH2_RABIT | Carbonic anhydrase II | Oryctolagus | <M><S><H><H><W><G><Y><G><K><H><N><G><P><E><H><W><H><K><D><F><P><I><A><N><G><E><R><Q><S><P><I><D><I><D><T><N><A><A><K><H><D><P><S><L><K><P><L><R><V><C><Y><E><H><P><I><S><R><R><I><I><N><N><G><H><S><F><N><V><E><F><D><D><S><H><D><K><T><V><L><K><E><G><P><L><E><G><T><Y><R><L><I><Q><F><H><F><H><W><G><S><S><D><G><Q><G><S><E><H... | Catalyzes the reversible hydration of carbon dioxide. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Essential for bone resorption and osteoclast differentiation. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorp... | P00919 |
A0LU48 | DOP_ACIC1 | Depupylase | Acidothermus | <M><H><R><V><M><G><I><E><T><E><Y><G><I><S><V><P><H><Q><P><N><A><N><A><M><A><A><S><S><Q><V><V><N><A><Y><A><P><I><G><A><P><A><Q><R><Q><A><R><W><D><F><E><E><E><N><P><L><R><D><A><R><G><F><E><V><A><R><E><A><A><D><P><S><Q><L><T><D><E><D><L><G><L><A><N><V><I><L><T><N><G><A><R><L><Y><V><D><H><A><H><P><E><Y><S><T><P><E><V><T><N... | Displays depupylase (DPUP) activity, removing conjugated Pup from target proteins; is thus involved in the recycling of Pup and may function similarly to deubiquitinases (DUBs) in eukaryotes to prevent or promote proteasomal degradation of certain proteins. Is also able to catalyze the deamidation of the C-terminal glu... | A0LU48 |
A0A2I6PIZ6 | NODD2_HYPPI | Nodulisporic acid biosynthesis cluster protein D2 | Hypoxylon | <M><D><S><T><G><R><Q><P><L><S><Q><D><G><Q><P><W><Q><A><L><A><S><G><L><G><F><P><D><E><D><Q><K><Y><W><W><S><V><M><A><P><L><L><G><E><L><M><K><W><A><N><Y><P><V><D><K><Q><Y><L><V><L><A><F><C><H><E><Y><I><L><P><F><C><G><P><R><P><T><A><E><G><G><I><F><W><P><T><L><I><T><K><D><G><T><P><F><E><P><S><L><N><F><Y><K><N><K><A><T><L><R... | Indole diterpene prenyltransferase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes nodulisporic acids (NA). Nodulisporic acid A (NAA) and its chemically modified derivatives are of particular significance because of their highly potent insecticidal activity against blood-feeding arthro... | A0A2I6PIZ6 |
Q9MZ13 | VDAC3_BOVIN | Outer mitochondrial membrane protein porin 3 | Bos | <M><C><N><T><P><T><Y><C><D><L><G><K><A><A><K><D><V><F><N><K><G><Y><G><F><G><M><V><K><I><D><L><R><T><K><S><C><S><G><V><E><F><S><T><S><G><H><A><Y><T><D><T><G><K><A><S><G><N><L><E><T><K><Y><K><I><C><N><Y><G><L><T><F><T><Q><K><W><N><T><D><N><T><L><G><T><E><I><S><W><E><N><K><L><A><E><G><L><K><L><T><L><D><T><I><F><V><P><N><T... | Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.<BOP> | Q9MZ13 |
Q12343 | MED4_YEAST | Mediator complex subunit 4 | Saccharomyces | <M><S><V><Q><D><T><K><A><V><E><F><S><M><G><H><I><R><S><S><S><V><S><L><V><A><E><A><T><S><N><T><N><S><E><D><K><L><S><K><V><Q><L><Y><E><D><L><C><R><Y><E><D><T><L><S><K><L><V><E><S><V><D><R><F><K><P><N><L><D><I><A><K><D><L><I><R><T><D><E><A><L><F><E><N><V><K><L><L><A><E><Y><D><N><I><Y><R><N><L><Q><K><I><D><K><D><S><E><E><L... | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a com... | Q12343 |
A5F3F8 | RLMN_VIBC3 | tRNA m2A37 methyltransferase | Vibrio | <M><T><T><E><K><V><N><L><L><D><F><D><R><K><G><L><R><T><F><F><A><E><E><L><G><E><K><A><F><R><A><E><Q><V><M><K><W><I><Y><H><F><G><C><D><D><F><D><Q><M><N><N><I><N><K><Q><L><R><E><K><L><K><A><K><C><E><I><R><A><P><Y><V><S><E><A><Q><H><S><A><D><G><T><I><K><W><A><M><R><V><G><D><Q><D><V><E><T><V><Y><I><P><E><D><D><R><A><T><L><C... | Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.<BOP> | A5F3F8 |
O76093 | FGF18_HUMAN | zFGF5 | Homo | <M><Y><S><A><P><S><A><C><T><C><L><C><L><H><F><L><L><L><C><F><Q><V><Q><V><L><V><A><E><E><N><V><D><F><R><I><H><V><E><N><Q><T><R><A><R><D><D><V><S><R><K><Q><L><R><L><Y><Q><L><Y><S><R><T><S><G><K><H><I><Q><V><L><G><R><R><I><S><A><R><G><E><D><G><D><K><Y><A><Q><L><L><V><E><T><D><T><F><G><S><Q><V><R><I><K><G><K><E><T><E><F><Y... | Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.<BOP> | O76093 |
C1D9H2 | CCME_LARHH | Heme chaperone CcmE | Laribacter | <M><H><P><K><R><K><K><R><L><L><I><V><L><A><G><L><A><V><V><A><V><A><S><G><L><I><L><N><A><F><R><S><N><L><V><F><F><H><T><P><T><E><I><A><A><G><Q><V><D><T><D><R><V><I><R><V><G><G><L><V><E><A><G><S><V><E><R><E><P><G><G><L><R><V><R><F><V><I><T><D><T><A><R><S><V><P><V><R><Y><E><G><I><L><P><D><L><F><R><E><G><H><G><T><V><V><Q><G... | Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.<BOP> | C1D9H2 |
O32377 | RECA_ALLVI | Recombinase A | Allochromatium | <M><D><E><N><R><K><K><A><L><A><A><A><L><T><Q><I><E><K><Q><F><G><K><G><S><V><M><R><M><G><D><V><G><A><V><R><N><I><E><A><I><S><T><G><S><L><G><L><D><L><A><L><G><I><G><G><V><P><K><G><R><V><I><E><I><Y><G><P><E><S><S><G><K><T><T><L><T><L><H><I><I><A><E><S><Q><K><L><G><G><T><A><A><F><V><D><A><E><H><A><L><D><P><V><Y><A><E><K><L... | Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP> | O32377 |
A4W787 | RISB_ENT38 | 6,7-dimethyl-8-ribityllumazine synthase | Enterobacter | <M><N><I><I><E><A><A><V><A><T><P><D><A><R><V><A><I><T><I><A><R><F><N><N><F><I><N><D><S><L><L><D><G><A><I><D><A><L><K><R><I><G><Q><V><K><D><E><N><I><T><V><V><W><V><P><G><A><Y><E><L><P><L><A><A><G><A><L><A><K><T><G><K><Y><D><A><V><I><A><L><G><T><V><I><R><G><G><T><A><H><F><E><Y><V><A><G><G><A><S><N><G><L><A><H><V><A><Q><E... | Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<BOP> | A4W787 |
A9LYF6 | NDHH_ACOAM | NADH-plastoquinone oxidoreductase subunit H | Acorus | <M><T><V><P><A><T><R><Q><D><L><M><I><V><N><M><G><P><H><H><P><S><M><H><G><V><L><R><L><I><V><T><L><D><G><E><D><V><I><D><C><E><P><I><L><G><Y><L><H><R><G><M><E><K><I><A><E><N><R><T><I><I><Q><Y><L><P><Y><V><T><R><W><D><Y><L><A><T><M><F><T><E><A><I><T><V><N><G><P><E><Q><L><G><N><I><Q><I><P><K><R><A><S><Y><I><R><V><I><M><L><E... | NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translo... | A9LYF6 |
A5GQJ6 | YCF3_SYNR3 | Photosystem I assembly protein Ycf3 | unclassified Synechococcus | <M><P><R><S><Q><R><N><D><N><F><I><D><K><S><F><T><V><M><A><D><L><I><L><K><V><L><P><T><N><Q><K><A><K><E><A><F><A><Y><Y><R><D><G><M><S><A><Q><G><D><G><E><Y><A><E><A><L><E><N><Y><Q><E><A><L><R><L><E><E><D><P><N><D><R><A><F><I><L><Y><N><M><A><L><V><Y><A><S><N><G><E><H><N><R><A><L><E><Q><Y><E><Q><A><L><A><L><N><A><K><M><P><Q... | Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits.<BOP> | A5GQJ6 |
A2YWA6 | ZHD2_ORYSI | Zinc-finger homeodomain protein 2 | Oryza sativa | <M><D><F><D><D><H><D><E><G><D><G><D><E><E><M><P><P><M><P><L><S><S><G><Y><D><A><P><M><Q><P><G><L><G><G><G><G><G><G><V><P><K><P><G><G><G><V><G><G><G><G><G><G><G><G><G><G><G><G><G><G><A><R><Y><R><E><C><L><K><N><H><A><V><G><I><G><G><H><A><V><D><G><C><G><E><F><M><A><S><G><E><E><G><S><I><D><A><L><R><C><A><A><C><G><C><H><R><N... | Putative transcription factor.<BOP> | A2YWA6 |
B0T192 | GATC_CAUSK | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C | unclassified Caulobacter | <M><A><I><D><A><A><T><V><R><K><V><A><R><L><A><R><I><A><T><P><E><D><R><L><E><P><L><A><Q><E><L><N><G><I><M><T><W><I><E><Q><L><A><Q><V><D><T><D><G><V><E><P><L><T><S><V><V><H><A><G><L><P><L><R><E><D><V><V><T><M><G><G><D><A><D><L><I><T><A><N><A><P><K><S><T><G><G><F><F><V><V><P><K><V><V><E> | Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ... | B0T192 |
Q9AKH1 | FER2_RICRI | Adrenodoxin-like protein | spotted fever group | <M><S><G><K><I><K><V><T><F><I><I><N><D><G><E><E><K><T><V><E><A><P><I><G><L><S><I><L><E><I><A><H><S><N><D><L><D><L><E><G><A><C><E><G><S><L><A><C><A><T><C><H><V><I><L><E><E><E><F><Y><N><K><L><K><K><P><T><E><A><E><E><D><M><L><D><L><A><F><G><L><T><D><T><S><R><L><G><C><Q><I><I><L><T><E><E><L><D><G><I><K><V><H><L><P><A><A><T... | Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.<BOP> | Q9AKH1 |
Q87LL6 | ARGP_VIBPA | HTH-type transcriptional regulator ArgP | Vibrio | <M><R><G><L><D><Y><K><W><I><E><A><L><D><A><V><V><Y><Q><G><S><F><E><R><A><A><E><H><L><F><V><S><Q><S><A><I><S><Q><R><I><K><Q><L><E><K><F><L><A><Q><P><V><L><I><R><E><Q><P><P><K><P><T><P><I><G><K><K><L><L><G><L><Y><R><R><V><R><L><L><E><H><E><I><L><P><E><I><K><N><D><T><T><T><R><P><V><Q><L><S><L><A><T><N><A><D><S><L><A><T><W... | Controls the transcription of genes involved in arginine and lysine metabolism.<BOP> | Q87LL6 |
Q8DW14 | PURA_STRMU | IMP--aspartate ligase | Streptococcus | <M><T><S><V><V><V><V><G><T><Q><W><G><D><E><G><K><G><K><I><T><D><F><L><S><A><D><A><E><V><I><A><R><Y><Q><G><G><D><N><A><G><H><T><I><V><I><D><G><K><K><F><K><L><H><L><I><P><S><G><I><F><F><P><E><K><V><S><V><I><G><N><G><M><V><V><N><P><K><S><L><V><E><E><L><D><Y><L><H><Q><E><G><V><A><T><D><N><L><R><I><S><D><R><A><H><I><I><L><P... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP> | Q8DW14 |
A4YKF1 | PROA_BRASO | Glutamyl-gamma-semialdehyde dehydrogenase | unclassified Bradyrhizobium | <M><T><A><P><L><K><A><I><D><G><S><A><D><L><P><Q><L><M><N><D><L><A><K><R><A><R><A><A><A><R><V><L><A><L><A><P><A><E><Q><K><N><R><A><L><E><A><M><E><R><R><I><R><A><R><A><D><V><I><I><A><A><N><A><E><D><V><A><E><A><K><A><V><G><V><T><P><S><F><V><D><R><L><T><L><T><P><A><R><V><A><A><M><A><D><G><I><A><V><V><R><G><V><A><D><P><V><G... | Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.<BOP> | A4YKF1 |
Q8DM00 | PRMA_THEVB | Ribosomal protein L11 methyltransferase | Thermosynechococcus | <M><V><Q><R><W><W><E><I><T><V><T><C><Q><A><E><A><E><E><L><V><Y><W><R><L><Q><S><F><G><C><Q><G><T><A><T><Q><L><Q><Q><G><R><V><L><I><Q><G><Y><V><P><Q><Q><R><V><S><L><L><D><I><A><A><L><G><V><W><I><E><Q><D><V><V><A><Q><G><Y><L><S><P><K><L><H><W><Q><L><V><N><E><Q><D><W><A><H><S><W><Q><A><Y><W><H><P><I><P><V><G><D><R><L><L><I... | Methylates ribosomal protein L11.<BOP> | Q8DM00 |
O46629 | ECHB_BOVIN | Beta-ketothiolase | Bos | <M><I><S><L><L><T><Y><T><L><K><N><L><P><N><T><S><K><W><A><L><R><F><C><M><R><P><L><S><S><S><S><Q><L><Q><A><A><A><A><S><Q><T><K><S><K><K><T><L><A><K><P><N><I><R><N><I><V><V><V><D><G><V><R><T><P><F><L><L><S><G><T><S><Y><K><D><L><M><P><H><D><L><A><R><A><A><L><S><G><L><L><H><R><T><S><V><P><K><D><V><V><D><Y><I><I><F><G><T><V... | Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among th... | O46629 |
A7GJW3 | PTH_BACCN | Peptidyl-tRNA hydrolase | Bacillus cereus group | <M><K><L><I><V><G><L><G><N><P><G><R><E><Y><E><L><T><R><H><N><I><G><F><M><A><I><D><E><L><A><K><R><W><N><I><S><L><N><E><Q><K><F><K><G><M><F><G><A><G><F><V><N><G><E><K><V><I><L><L><K><P><L><T><Y><M><N><L><S><G><E><S><I><R><P><L><M><D><Y><Y><K><I><D><L><E><D><F><I><I><M><Y><D><D><L><D><L><P><V><G><K><L><R><L><R><M><K><G><S... | The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.<BOP> | A7GJW3 |
C3P786 | DEOC_BACAA | Phosphodeoxyriboaldolase | Bacillus cereus group | <M><N><I><A><K><L><I><D><H><T><I><L><K><A><N><T><T><K><E><D><V><M><K><V><I><E><E><A><K><E><Y><K><F><A><S><V><C><I><N><P><T><W><V><K><L><A><A><E><E><L><A><G><H><D><V><D><V><C><T><V><I><G><F><P><L><G><A><S><T><T><E><T><K><A><F><E><T><K><D><A><I><A><K><G><A><T><E><V><D><M><V><I><N><V><G><A><L><K><D><G><D><N><E><L><V><E><K... | Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.<BOP> | C3P786 |
P17867 | CISA_BACSU | Stage IV sporulation protein CA | Bacillus | <M><I><A><I><Y><V><R><V><S><T><E><E><Q><A><I><K><G><S><S><I><D><S><Q><I><E><A><C><I><K><K><A><G><T><K><D><V><L><K><Y><A><D><E><G><F><S><G><E><L><L><E><R><P><A><L><N><R><L><R><E><D><A><S><K><G><L><I><S><Q><V><I><C><Y><D><P><D><R><L><S><R><K><L><M><N><Q><L><I><I><D><D><E><L><R><K><R><N><I><P><L><I><F><V><N><G><E><Y><A><N... | Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of SpoIIIC and SpoIVCB to form sigma K factor.<BOP> | P17867 |
A5W9A9 | SSRP_PSEP1 | Small protein B | Pseudomonas | <M><A><K><Q><K><K><H><P><T><G><T><I><A><Q><N><K><K><A><R><H><D><Y><F><I><E><H><K><F><E><A><G><L><V><L><S><G><W><E><V><K><S><L><R><A><G><K><A><H><L><T><D><S><Y><V><L><L><K><D><G><E><A><W><L><F><G><S><H><I><T><P><L><T><T><A><S><T><H><V><I><A><D><P><T><R><T><R><K><L><L><L><N><K><R><E><L><E><R><V><E><A><A><V><A><Q><K><G><Y... | Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb... | A5W9A9 |
Q5U1X0 | TAF11_RAT | Transcription initiation factor TFIID 28 kDa subunit | Rattus | <M><D><N><L><G><E><S><P><T><D><K><A><G><E><P><G><E><S><E><E><T><R><A><T><P><G><A><P><V><S><A><D><T><E><G><I><P><E><E><T><D><Q><V><G><D><A><D><S><K><E><A><A><A><E><E><S><E><L><K><S><Q><D><V><S><D><V><T><A><A><E><R><E><D><P><S><L><L><T><P><A><A><K><K><L><K><L><D><T><K><D><K><K><E><K><K><Q><K><V><D><E><D><E><I><Q><K><M><Q... | The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID c... | Q5U1X0 |
Q2YLI7 | PROA_BRUA2 | Glutamyl-gamma-semialdehyde dehydrogenase | Brucella | <M><T><K><D><I><A><Q><V><M><A><E><V><G><R><K><A><K><A><A><A><A><P><L><S><I><A><T><S><E><Q><K><N><K><A><L><N><A><A><A><D><A><I><L><E><A><R><A><D><I><L><E><A><N><R><L><D><L><A><N><A><E><K><N><G><M><A><A><S><F><V><D><R><L><T><L><N><E><A><R><I><D><A><I><A><E><G><I><R><A><I><A><T><L><P><D><P><V><G><E><V><I><A><E><W><D><R><P... | Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.<BOP> | Q2YLI7 |
P69686 | PSBD_TOBAC | Photosystem Q(A) protein | Nicotiana | <M><T><I><A><L><G><K><F><T><K><D><E><N><D><L><F><D><I><M><D><D><W><L><R><R><D><R><F><V><F><V><G><W><S><G><L><L><L><F><P><C><A><Y><F><A><V><G><G><W><F><T><G><T><T><F><V><T><S><W><Y><T><H><G><L><A><S><S><Y><L><E><G><C><N><F><L><T><A><A><V><S><T><P><A><N><S><L><A><H><S><L><L><L><L><W><G><P><E><A><Q><G><D><F><T><R><W><C><Q... | Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photoni... | P69686 |
P33536 | RBL_OSMCI | Ribulose bisphosphate carboxylase large chain | Osmundastrum | <G><I><G><F><K><A><G><V><K><D><Y><R><L><T><H><Y><T><P><D><Y><E><T><K><D><T><D><I><L><A><A><F><R><M><T><P><Q><P><G><V><P><A><E><E><A><G><A><A><V><A><A><E><S><S><T><G><T><W><T><T><V><W><T><D><G><L><T><S><L><D><R><Y><K><G><R><C><Y><D><I><E><P><V><A><G><E><E><N><Q><Y><I><A><Y><V><A><Y><P><L><D><L><F><E><E><G><S><V><T><N><M... | RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.<BOP> | P33536 |
P15241 | K2M2_SHEEP | Keratin, type II microfibrillar, component 7C | Ovis | <C><G><F><S><T><V><G><S><G><F><G><S><R><A><F><S><C><V><S><A><C><G><P><R><P><G><R><C><C><I><T><A><A><P><Y><R><G><I><S><C><Y><R><G><L><T><G><G><F><G><S><R><S><V><C><G><G><F><R><A><G><S><C><G><R><S><F><G><Y><R><S><G><G><V><C><G><P><S><P><P><C><I><T><T><V><S><V><N><E><S><L><L><T><P><L><N><L><E><I><D><P><N><A><Q><C><V><K><Q... | Wool microfibrillar keratin.<BOP> | P15241 |
A6TCG5 | GLYA_KLEP7 | Serine hydroxymethyltransferase | Klebsiella | <M><L><K><R><E><M><N><I><A><D><Y><D><A><E><L><W><Q><A><M><E><Q><E><K><V><R><Q><E><E><H><I><E><L><I><A><S><E><N><Y><T><S><P><R><V><M><Q><A><Q><G><S><Q><L><T><N><K><Y><A><E><G><Y><P><G><K><R><Y><Y><G><G><C><E><Y><V><D><V><V><E><Q><L><A><I><D><R><A><K><E><L><F><G><A><D><Y><A><N><V><Q><P><H><S><G><S><Q><A><N><F><A><V><Y><T... | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a... | A6TCG5 |
P28808 | LCRF_YERPE | Thermoregulatory protein LcrF | Yersinia | <M><A><S><L><E><I><I><K><L><E><W><V><T><P><I><F><K><V><V><E><H><S><Q><D><G><L><Y><I><L><L><Q><G><Q><I><S><W><Q><S><S><G><Q><T><Y><D><L><D><E><G><N><M><L><F><L><R><R><G><S><Y><A><V><R><C><G><T><K><E><P><C><Q><L><L><W><I><P><L><P><G><S><F><L><S><T><F><L><H><R><F><G><S><L><L><S><E><I><G><R><D><N><S><T><P><K><P><L><L><I><F... | Transcriptional activator of the thermally regulated virulent yopE gene. LcrF activity could be modulated by the interaction with an inducer molecule serving as a temperature messenger. The availability of the messenger would in turn be controlled by a temperature-responsive process serving as a cellular thermometer.<B... | P28808 |
P0C0N1 | OTC_STAES | Ornithine carbamoyltransferase | Staphylococcus | <M><K><N><L><R><N><R><S><F><L><T><L><L><D><F><S><R><Q><E><V><E><F><L><L><T><L><S><E><D><L><K><R><A><K><Y><I><G><T><E><K><P><M><L><K><N><K><N><I><A><L><L><F><E><K><D><S><T><R><T><R><C><A><F><E><V><A><A><H><D><Q><G><A><H><V><T><Y><L><G><P><T><G><S><Q><M><G><K><K><E><T><A><K><D><T><A><R><V><L><G><G><M><Y><D><G><I><E><Y><R... | Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.<BOP> | P0C0N1 |
Q6LQC0 | HMUV_PHOPR | Hemin import ATP-binding protein HmuV | Photobacterium | <M><T><F><G><P><Q><P><N><S><L><T><P><L><I><N><N><Q><I><C><K><K><K><V><A><I><H><A><Q><G><L><N><L><I><L><G><G><K><T><L><L><D><N><F><D><I><D><I><N><A><G><E><V><T><A><L><L><G><P><N><G><A><G><K><S><S><L><L><K><V><L><C><G><E><I><E><A><T><G><S><I><E><F><F><G><Q><N><R><K><Q><W><S><A><K><A><L><A><K><H><L><G><V><L><P><Q><H><S><T... | Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.<BOP> | Q6LQC0 |
Q21C20 | ISPG_RHOPB | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase | Rhodopseudomonas | <M><N><K><L><E><N><P><L><S><H><D><V><A><G><P><A><P><R><H><K><T><T><Q><V><M><V><G><D><V><A><V><G><G><G><A><P><I><V><V><Q><S><M><T><N><T><D><T><A><D><V><A><G><T><V><E><Q><V><A><A><L><T><R><A><G><S><E><L><V><R><I><T><V><D><R><E><E><A><A><A><A><V><P><H><I><R><D><A><L><R><K><R><G><I><T><T><P><L><I><G><D><F><H><Y><I><G><H><K... | Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.<BOP> | Q21C20 |
Q6MBU9 | RIMO_PARUW | Ribosome maturation factor RimO | Candidatus Protochlamydia | <M><L><P><I><L><K><N><Q><G><V><K><K><D><Q><N><H><I><A><L><K><N><D><S><C><E><S><S><S><P><C><F><D><H><E><G><N><K><I><N><F><I><S><L><G><C><P><R><N><L><V><D><S><E><V><M><L><G><I><L><L><K><A><G><Y><E><V><A><P><T><L><E><E><A><D><Y><L><V><I><N><T><C><G><F><L><E><A><S><R><Q><E><S><M><D><T><V><E><E><V><L><S><Q><R><K><K><T><A><K... | Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.<BOP> | Q6MBU9 |
B5FG22 | RS14_ALIFM | 30S ribosomal protein S14 | Aliivibrio | <M><A><K><Q><S><M><K><A><R><E><A><K><R><A><K><L><V><A><K><F><A><E><K><R><A><A><L><K><V><L><I><S><D><V><N><A><S><E><E><E><R><W><D><A><V><L><K><L><Q><A><L><P><R><D><S><S><A><S><R><Q><R><N><R><C><N><Q><T><G><R><P><H><G><Y><L><R><K><F><G><L><S><R><I><K><V><R><E><A><C><M><K><G><E><I><P><G><L><R><K><A><S><W> | Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.<BOP> | B5FG22 |
A4XL78 | RLMN_CALS8 | tRNA m2A37 methyltransferase | Caldicellulosiruptor | <M><K><R><L><I><K><D><F><T><F><D><E><L><K><K><W><V><E><E><T><G><E><K><P><F><R><A><N><Q><I><F><E><W><L><Y><K><K><N><A><T><D><V><N><S><F><T><N><I><P><T><Q><L><R><K><R><I><E><E><E><F><I><L><N><S><L><R><V><V><K><Y><E><S><D><G><E><S><I><K><F><L><L><E><L><V><D><G><N><A><I><E><S><V><F><L><P><Y><K><Y><G><N><A><I><C><I><S><T><Q... | Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.<BOP> | A4XL78 |
B8HX39 | ANMK_CYAP4 | AnhMurNAc kinase | unclassified Cyanothece | <M><H><V><I><G><L><I><S><G><T><S><V><D><G><I><D><A><A><L><V><D><L><S><G><T><S><L><D><L><Q><V><E><L><L><A><A><H><T><Y><P><Y><S><E><P><V><R><S><Q><I><I><S><L><C><K><G><E><A><I><P><L><A><E><L><A><L><L><D><E><A><I><A><Q><E><F><A><Q><A><A><L><E><I><Q><Q><G><Q><P><A><A><E><L><I><G><S><H><G><Q><T><V><Y><H><R><P><V><I><G><N><T... | Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall ... | B8HX39 |
P58602 | CPI4_SOLTU | PCPI-23 | Solanum | <P><V><L><Q><V><V><R><D><I><H><G><D><I><L><T><P><D><S><R><Y><I><L> | Inhibitor of papain (cysteine protease). Does not inhibit trypsin, chymotrypsin nor elastase (serine proteases). May protect the plant by inhibiting proteases of invading organisms.<BOP> | P58602 |
P0A3S9 | PAL_BRUAB | Outer membrane lipoprotein Omp16 | Brucella | <M><R><R><I><Q><S><I><A><R><S><P><I><A><I><A><L><F><M><S><L><A><V><A><G><C><A><S><K><K><N><L><P><N><N><A><G><D><L><G><L><G><A><G><A><A><T><P><G><S><S><Q><D><F><T><V><N><V><G><D><R><I><F><F><D><L><D><S><S><L><I><R><A><D><A><Q><Q><T><L><S><K><Q><A><Q><W><L><Q><R><Y><P><Q><Y><S><I><T><I><E><G><H><A><D><E><R><G><T><R><E><Y... | Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP> | P0A3S9 |
Q8FK20 | ENTS_ECOL6 | Enterobactin exporter EntS | Escherichia | <M><N><K><Q><S><W><L><L><N><L><S><L><L><K><T><H><P><A><F><R><A><V><F><L><A><R><F><I><S><I><V><S><L><G><L><L><G><V><A><V><P><V><Q><I><Q><M><M><T><H><S><T><W><Q><V><G><L><S><V><T><L><T><G><G><A><M><F><V><G><L><M><V><G><G><V><L><A><D><R><Y><E><R><K><K><V><I><L><L><A><R><G><T><C><G><I><G><F><I><G><L><C><L><N><A><L><L><P><E... | Component of an export pathway for enterobactin.<BOP> | Q8FK20 |
C4LEG3 | AROA_TOLAT | 5-enolpyruvylshikimate-3-phosphate synthase | Tolumonas | <M><N><T><L><T><L><E><P><I><A><R><V><E><G><T><V><N><L><P><G><S><K><S><V><S><N><R><A><L><L><L><A><A><L><A><R><G><T><T><R><L><T><N><L><L><D><S><D><D><I><R><H><M><L><N><A><L><K><T><L><G><V><S><Y><E><L><S><A><N><K><T><E><C><T><V><H><G><L><G><R><A><F><S><S><S><E><P><V><N><L><F><L><G><N><A><G><T><A><M><R><P><L><C><A><A><L><C... | Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.<BOP> | C4LEG3 |
A2CBN5 | MTND_PROM3 | Acireductone dioxygenase (Ni(2+)-requiring) | Prochlorococcus | <M><S><R><L><S><I><H><P><E><G><N><T><N><A><T><S><P><A><E><P><L><L><E><S><D><D><P><A><V><I><K><A><E><L><A><K><R><G><I><E><F><Q><H><W><P><A><K><V><K><L><H><Q><N><S><I><E><S><D><I><L><A><A><Y><A><V><E><I><A><R><V><Q><A><D><G><R><Y><P><T><V><D><A><I><R><I><T><P><D><H><P><D><R><E><A><L><R><Q><K><F><L><A><E><H><T><H><A><E><D... | Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine... | A2CBN5 |
Q20EU1 | CEMA_OLTVI | Chloroplast envelope membrane protein | Oltmannsiellopsis | <M><D><S><E><S><Q><L><L><E><G><A><V><E><K><I><G><L><I><P><R><S><I><I><R><T><I><N><R><F><Q><Q><Q><L><F><P><D><A><V><E><Y><F><I><Q><E><F><R><V><S><R><S><Q><V><L><V><S><L><Q><C><L><L><T><L><I><I><I><P><L><F><I><H><F><F><A><K><T><V><F><L><T><P><C><I><E><Y><V><W><N><T><Y><K><T><D><I><F><L><N><S><Y><Q><Q><E><Q><A><L><T><E><M... | May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake into chloroplasts.<BOP> | Q20EU1 |
Q0IQN6 | DRB8_ORYSJ | dsRNA-binding protein 8 | Oryza sativa | <M><D><M><P><P><T><P><L><P><P><E><T><A><N><T><S><P><A><P><N><G><A><T><A><G><I><R><V><E><N><C><Y><V><F><K><S><R><L><Q><E><Y><A><Q><K><T><G><L><Q><T><P><E><Y><H><T><F><K><E><G><P><S><H><E><P><V><F><K><S><T><V><V><I><N><N><T><S><Y><D><S><L><P><G><F><F><N><R><K><A><A><E><Q><S><A><A><E><V><A><L><M><E><I><V><K><S><I><P><A><N... | Binds double-stranded RNA.<BOP> | Q0IQN6 |
P85117 | TX1_GRARO | GrTx1 | Grammostola | <Y><C><Q><K><W><M><W><T><C><D><S><K><R><K><C><C><E><D><M><V><C><Q><L><W><C><K><K><R><L> | Inhibits voltage-gated sodium channels Nav1.1/SCN1A (IC(50)=630 nM), Nav1.2/SCN2A (IC(50)=230 nM), Nav1.3/SCN3A (IC(50)=770 nM), Nav1.4/SCN4A (IC(50)=1290 nM), Nav1.6/SCN8A (IC(50)=630 nM), Nav1.7/SCN9A (IC(50)=15.3-1000 nM) and potassium channels Kv11.1/KCNH2 (IC(50)=4.2 uM).<BOP> | P85117 |
P10901 | FUCO_DICDI | Alpha-L-fucoside fucohydrolase | Dictyostelium | <M><K><M><I><I><I><F><F><I><L><L><I><L><N><L><I><K><S><Q><Q><Y><G><P><T><W><D><Q><I><N><S><R><P><L><P><G><W><Y><D><D><V><K><F><G><I><F><I><H><F><G><I><Y><S><V><P><A><F><A><N><G><G><Y><A><E><W><Y><W><W><T><L><K><N><P><S><S><D><G><G><A><T><Q><R><Y><H><E><K><E><F><G><A><N><F><T><Y><Q><D><F><V><S><R><F><D><C><R><L><F><D><A... | Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.<BOP> | P10901 |
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