accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
P51038
CISY2_RHITR
Citrate synthase, plasmid
Rhizobium
<M><D><N><N><N><A><C><V><L><V><D><G><H><S><A><E><L><K><L><R><S><S><T><I><G><P><N><V><L><G><I><G><S><L><Y><E><Q><T><K><M><F><T><Y><D><P><G><F><T><S><T><A><S><C><E><S><S><I><T><F><I><D><G><D><E><G><V><L><L><H><R><G><Y><P><I><E><Q><L><A><E><H><G><D><F><L><E><V><C><Y><L><L><L><Y><G><E><L><P><T><A><A><Q><K><K><D><F><D><Y><R...
The exact function of the plasmid-encoded citrate synthase is not clear, it could help nodulation by allowing the bacteria to use citrate as a chelator of iron and calcium.<BOP>
P51038
P95334
DNAK_MYXXD
Heat shock protein 70
Myxococcus
<M><G><K><V><I><G><I><D><L><G><T><T><N><S><C><V><A><V><M><E><G><G><E><P><V><V><I><P><N><S><E><G><S><R><T><T><P><S><M><V><G><F><T><D><S><G><E><R><L><V><G><Q><I><A><K><R><Q><A><I><T><N><P><E><N><T><V><F><A><A><K><R><L><I><G><R><K><F><D><S><P><E><G><K><K><A><I><G><V><S><P><F><K><V><A><S><S><P><N><G><D><A><W><V><E><I><R><G...
Potential chaperone for other proteins involved in social motility.<BOP>
P95334
P69845
GRAA_GRASX
Grammistin Gs A
Grammistes
<W><W><R><E><L><L><K><K><L><A><F><T><A><A><G><H><L><G><S><V><L><A><A><K><Q><S><G><W>
Thanks to its amphiphilic alpha-helice(s), it may integrate into membrane phospholipids, leading to lysis of the membrane. Has no substantial hemolytic activity. Has antibacterial activity with a broad spectrum against various species of bacteria including both Gram-positive and Gram-negative groups.<BOP>
P69845
Q9YFA8
DCD_AERPE
Deoxycytidine triphosphate deaminase
Aeropyrum
<M><I><L><S><D><R><D><I><R><A><L><L><A><I><G><D><L><V><V><E><P><L><S><G><D><T><V><R><E><N><G><L><D><L><R><L><G><R><G><F><C><R><F><K><R><S><D><R><V><L><D><P><R><A><P><G><S><P><G><E><F><Y><E><C><G><E><G><D><E><I><I><V><G><P><G><E><H><M><L><L><H><T><Q><E><Y><I><R><L><P><G><Y><V><A><G><L><V><N><L><R><S><T><W><A><R><T><G><I...
Catalyzes the deamination of dCTP to dUTP.<BOP>
Q9YFA8
Q9BQ24
ZFY21_HUMAN
Zinc finger FYVE domain-containing protein 21
Homo
<M><S><S><E><V><S><A><R><R><D><A><K><K><L><V><R><S><P><S><G><L><R><M><V><P><E><H><R><A><F><G><S><P><F><G><L><E><E><P><Q><W><V><P><D><K><E><C><R><R><C><M><Q><C><D><A><K><F><D><F><L><T><R><K><H><H><C><R><R><C><G><K><C><F><C><D><R><C><C><S><Q><K><V><P><L><R><R><M><C><F><V><D><P><V><R><Q><C><A><E><C><A><L><V><S><L><K><E><A...
Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta-1/ITGB1 cell surface expression.<BOP>
Q9BQ24
Q5LW55
RL16_RUEPO
50S ribosomal protein L16
Ruegeria
<M><L><Q><P><K><R><T><K><F><R><K><M><F><K><G><R><I><H><G><L><A><K><G><G><S><D><L><N><F><G><T><Y><G><L><K><A><L><E><P><E><R><V><T><A><R><Q><I><E><A><A><R><R><A><M><T><R><H><M><K><R><Q><G><R><V><W><I><R><I><F><P><D><T><P><V><T><S><K><P><T><E><V><R><M><G><K><G><K><G><S><V><D><Y><W><A><C><K><V><K><P><G><R><V><M><F><E><I><D...
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP>
Q5LW55
Q8Z538
ARNT_SALTI
Undecaprenyl phosphate-alpha-L-Ara4N transferase
Salmonella
<M><K><S><I><R><Y><Y><L><A><F><A><A><F><I><A><L><Y><Y><V><I><P><V><N><S><R><L><L><W><Q><P><D><E><T><R><Y><A><E><I><S><R><E><M><L><A><S><G><D><W><I><V><P><H><F><L><G><L><R><Y><F><E><K><P><I><A><G><Y><W><I><N><S><L><G><Q><W><L><F><G><A><T><N><F><G><V><R><A><G><A><I><L><T><T><L><L><A><A><A><L><V><A><W><L><T><F><R><L><W><R...
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.<BOP>
Q8Z538
Q8EN13
PXPA_OCEIH
5-oxoprolinase (ATP-hydrolyzing) subunit A
Oceanobacillus
<M><Q><Y><Q><V><D><L><N><S><D><I><G><E><S><Y><G><A><Y><T><I><G><Q><D><D><E><V><M><E><F><I><T><S><A><N><I><A><C><G><Y><H><A><G><D><H><N><I><I><H><R><T><I><D><L><A><I><K><N><N><V><A><I><G><A><H><P><G><L><Q><D><L><I><G><F><G><R><R><P><M><Q><I><S><P><E><E><V><Y><Q><L><T><V><Y><Q><I><G><A><V><Q><A><F><A><Q><V><K><G><H><N><L...
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.<BOP>
Q8EN13
Q00728
H2A4_RAT
Histone H2A, testis
Rattus
<M><S><G><R><A><K><Q><G><G><K><A><R><A><K><A><K><S><R><S><F><R><A><G><L><Q><F><P><V><G><R><V><H><R><L><L><R><Q><G><N><Y><A><E><R><I><G><A><G><T><P><V><Y><L><A><A><V><L><E><Y><L><T><A><E><I><L><E><L><A><G><N><A><A><R><D><N><K><K><T><R><I><I><P><R><H><L><Q><L><A><I><R><N><D><E><E><L><N><K><L><L><G><R><V><T><I><A><Q><G><G...
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v...
Q00728
A6GW04
SYY_FLAPJ
Tyrosyl-tRNA synthetase
Flavobacterium
<M><K><N><L><V><E><E><L><K><W><R><G><L><F><H><D><M><M><P><G><T><E><E><Q><L><T><K><E><S><T><T><A><Y><I><G><F><D><P><T><A><D><S><L><H><I><G><S><M><V><Q><I><I><L><L><V><H><L><K><N><F><G><H><K><P><I><A><L><I><G><G><A><T><G><M><I><G><D><P><S><G><K><S><D><E><R><N><L><L><D><E><A><T><L><N><K><N><V><A><G><I><K><A><V><L><S><S><F...
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<BOP>
A6GW04
Q30QQ0
ATPG_SULDN
F-ATPase gamma subunit
Sulfurimonas
<M><A><N><L><K><D><I><Q><R><Q><I><K><S><V><S><N><T><Q><K><T><T><R><A><M><K><L><V><S><T><A><K><L><R><R><A><E><E><L><A><K><R><S><R><L><Y><A><A><K><M><N><Q><V><I><A><E><I><A><G><R><I><R><C><N><K><V><G><G><I><D><N><R><C><F><S><K><I><E><D><P><K><T><V><D><I><I><F><V><T><A><D><K><G><L><C><G><G><F><N><I><Q><T><I><K><A><V><K><K...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP>
Q30QQ0
Q48AT8
TUSA_COLP3
Sulfur carrier protein TusA
Colwellia
<M><T><T><T><I><F><Q><Q><T><N><H><T><L><D><A><I><G><L><R><C><P><E><P><V><M><M><V><R><M><N><I><R><K><I><A><S><G><E><T><L><L><I><K><C><D><D><P><S><T><A><R><D><I><P><S><F><C><R><F><M><E><H><E><L><L><A><K><Q><T><D><T><L><P><F><L><Y><V><I><K><K><N>
Sulfur carrier protein which probably makes part of a sulfur-relay system.<BOP>
Q48AT8
Q94CE5
GATP_ARATH
Protein POLLEN-PISTIL INCOMPATIBILITY 2
Arabidopsis
<M><V><V><I><N><S><L><R><R><L><A><R><T><T><Q><V><H><L><H><S><K><Y><A><T><C><M><S><G><N><S><T><S><R><R><I><F><T><T><E><A><A><P><E><K><K><N><T><V><G><S><K><G><H><D><M><L><A><P><F><T><A><G><W><Q><S><A><D><L><D><P><L><V><I><A><K><S><E><G><S><Y><V><Y><D><D><T><G><K><K><Y><L><D><S><L><A><G><L><W><C><T><A><L><G><G><N><E><P><R...
Transaminase that degrades gamma-amino butyric acid (GABA) and uses pyruvate or glyoxylate as amino-group acceptor, but not 2-oxoglutarate. The pyruvate-dependent activity is reversible while the glyoxylate-dependent activity is irreversible. Cannot use beta-alanine, ornithine, acetylornithine, serine, glycine, asparag...
Q94CE5
A8FYZ3
ISPE_SHESH
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase
Shewanella
<M><S><N><K><L><S><Q><G><W><P><A><P><A><K><L><N><L><F><L><H><I><N><G><R><R><A><D><G><Y><H><E><L><Q><T><L><F><Q><F><I><D><Y><C><D><Y><L><D><F><K><V><T><D><T><S><S><L><K><L><H><S><N><M><G><A><A><V><A><D><S><D><N><L><I><L><R><A><A><K><L><L><Q><Q><V><S><G><C><A><K><G><A><E><I><W><L><D><K><R><L><P><M><G><G><G><I><G><G><G><S...
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.<BOP>
A8FYZ3
Q4JB92
MTNA_SULAC
S-methyl-5-thioribose-1-phosphate isomerase
Sulfolobus
<M><H><F><P><L><I><P><M><V><K><L><E><E><I><K><Q><I><F><K><P><K><L><L><P><I><I><W><N><K><T><K><L><T><L><L><D><Q><S><R><L><P><F><E><K><I><Y><V><D><V><T><K><V><E><E><V><S><D><A><I><R><T><M><K><V><R><G><A><P><A><I><G><I><T><A><G><Y><G><M><V><L><A><I><Q><D><S><I><S><L><E><K><A><I><S><D><L><T><K><A><K><K><I><L><D><E><S><R><P...
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).<BOP>
Q4JB92
Q9FVU0
P24D4_ARATH
p24 family protein delta4
Arabidopsis
<M><K><K><K><M><I><P><T><T><I><L><L><S><A><L><I><F><S><L><S><P><I><C><E><A><V><W><L><T><V><P><H><T><G><S><K><C><V><S><E><E><I><Q><S><N><V><I><V><L><A><D><Y><L><V><I><S><E><E><H><S><I><F><P><T><V><S><V><K><V><T><A><P><Y><G><T><V><L><H><H><R><E><N><T><T><N><G><Q><F><A><F><T><T><Q><E><S><G><T><Y><L><A><C><F><E><A><D><A><K...
Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Required for trafficking GLL23, a component of the PYK10 complex. May act as a receptor facilitating its packing into COPII carriers and export from the endoplasmic reticulum.<BOP>
Q9FVU0
Q2JXH1
PSAJ_SYNJA
Photosystem I reaction center subunit IX
unclassified Synechococcus
<M><S><D><F><T><K><F><L><T><T><A><P><V><A><F><I><L><F><S><S><F><V><F><A><L><F><I><E><I><N><R><F><F><P><D><I><L><T><F>
May help in the organization of the PsaE and PsaF subunits.<BOP>
Q2JXH1
Q9CHW5
SERC_LACLA
Phosphohydroxythreonine aminotransferase
Lactococcus
<M><I><Y><N><F><G><A><G><P><S><V><L><P><K><E><V><L><K><K><V><Q><E><E><L><L><D><F><E><K><S><G><M><S><V><M><E><I><S><H><R><S><K><A><F><Q><K><V><I><D><E><A><E><N><D><L><R><D><L><M><S><I><P><Q><N><Y><K><I><L><F><L><Q><G><G><A><S><S><Q><F><S><M><V><P><M><N><L><A><I><G><K><K><A><Y><Y><N><I><S><G><A><F><G><E><K><A><Y><D><E><A...
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.<BOP>
Q9CHW5
B2VBV2
GAL1_ERWT9
Galactose kinase
Erwinia
<M><S><L><Q><T><T><T><Q><Q><I><F><S><C><A><F><G><Y><A><P><T><H><T><V><Q><A><P><G><R><V><N><L><I><G><E><H><T><D><Y><N><D><G><F><V><L><P><C><A><I><D><Y><Q><T><V><I><A><C><A><K><R><S><D><R><Q><V><R><T><I><A><V><D><Y><D><N><Q><Q><D><I><F><S><L><D><E><P><I><E><R><H><P><Q><Q><L><W><S><D><Y><V><R><G><V><V><K><Y><L><Q><Q><R><A...
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).<BOP>
B2VBV2
Q68RJ9
CART_BOVIN
CART(42-89)
Bos
<M><E><S><P><R><L><R><L><L><P><L><L><G><A><A><L><L><L><L><L><P><L><L><G><A><L><A><Q><E><D><A><E><L><Q><P><R><A><L><D><I><Y><S><A><V><E><D><A><S><H><E><K><E><L><I><E><A><L><Q><E><V><L><K><K><L><K><S><K><R><I><P><I><Y><E><K><K><Y><G><Q><V><P><M><C><D><A><G><E><Q><C><A><V><R><K><G><A><R><I><G><K><L><C><D><C><P><R><G><T><S...
Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus.<BOP>
Q68RJ9
Q4FU58
NUOH_PSYA2
NDH-1 subunit H
Psychrobacter
<M><Q><V><T><R><I><I><P><D><V><P><S><F><L><A><S><M><M><T><F><D><T><W><S><I><L><F><M><V><V><Q><S><L><V><I><F><L><V><V><V><I><V><A><A><M><M><I><I><Y><E><R><R><M><L><A><L><W><Q><D><R><Y><G><P><N><R><V><G><P><F><G><S><L><Q><L><V><A><D><M><L><K><I><F><F><K><E><D><W><T><P><N><F><T><D><K><F><M><F><T><L><A><P><A><V><A><M><F><T...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
Q4FU58
Q4JU23
RSMA_CORJK
S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase
Corynebacterium
<M><V><N><E><R><K><I><R><L><L><G><P><N><E><I><R><Q><L><A><E><E><L><D><L><N><P><T><K><K><L><G><Q><N><F><V><H><D><P><N><T><V><R><K><I><V><K><A><A><D><V><T><A><D><D><N><V><V><E><I><G><P><G><L><G><S><L><T><L><A><L><L><E><A><G><A><S><V><T><A><V><E><I><D><P><R><L><A><A><K><L><P><A><T><L><E><E><Q><G><A><A><E><A><D><V><A><V><I...
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.<BOP>
Q4JU23
O43745
CHP2_HUMAN
Hepatocellular carcinoma-associated antigen 520
Homo
<M><G><S><R><S><S><H><A><A><V><I><P><D><G><D><S><I><R><R><E><T><G><F><S><Q><A><S><L><L><R><L><H><H><R><F><R><A><L><D><R><N><K><K><G><Y><L><S><R><M><D><L><Q><Q><I><G><A><L><A><V><N><P><L><G><D><R><I><I><E><S><F><F><P><D><G><S><Q><R><V><D><F><P><G><F><V><R><V><L><A><H><F><R><P><V><E><D><E><D><T><E><T><Q><D><P><K><K><P><E...
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferat...
O43745
B0TFC9
FOLD_HELMI
Methenyltetrahydrofolate cyclohydrolase
Heliomicrobium
<M><T><A><Q><Y><I><D><G><K><A><I><A><A><Q><L><R><A><E><I><K><A><E><V><A><S><L><R><E><Q><G><I><V><P><K><L><A><V><I><L><V><G><D><D><P><A><S><V><V><Y><A><R><S><K><E><K><A><A><A><N><L><G><I><A><F><E><L><F><T><L><P><G><D><T><T><E><A><A><L><L><A><L><I><E><R><L><N><A><D><A><A><V><H><G><I><M><V><E><L><P><L><P><K><Q><I><S><K><E...
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP>
B0TFC9
Q2J725
RIMP_FRACC
Ribosome maturation factor RimP
Frankia
<M><G><S><A><D><D><Q><A><S><R><M><R><E><G><T><V><E><V><V><G><A><G><E><A><G><R><A><R><D><R><S><P><S><G><S><A><R><G><R><G><G><V><R><T><A><L><R><A><R><L><A><A><G><L><A><D><A><G><F><D><L><E><D><V><T><V><T><R><A><G><S><R><S><V><V><R><V><V><V><D><R><D><G><G><V><D><L><D><A><V><A><D><A><S><R><L><A><S><E><L><L><D><A><A><E><T><D...
Required for maturation of 30S ribosomal subunits.<BOP>
Q2J725
B1LAW8
MURB_THESQ
UDP-N-acetylmuramate dehydrogenase
unclassified Thermotoga
<M><D><K><I><F><E><S><L><Y><K><A><G><C><D><V><R><M><F><E><K><L><S><C><H><T><S><I><K><I><G><G><R><V><K><Y><L><V><L><P><N><D><V><F><S><L><E><R><A><I><T><V><L><K><D><F><P><F><Q><I><M><G><L><G><T><N><L><L><V><Q><D><E><D><L><D><I><A><V><L><K><T><E><R><L><N><Q><I><E><I><K><G><E><K><V><L><V><E><S><G><T><P><L><K><R><L><C><L><F...
Cell wall formation.<BOP>
B1LAW8
Q9ZQB9
CSLCC_ARATH
Cellulose synthase-like protein C12
Arabidopsis
<M><A><P><K><F><E><W><W><A><K><G><N><N><N><N><T><R><K><G><T><P><V><V><V><K><M><E><N><P><N><N><W><S><M><V><E><L><E><S><P><S><H><D><D><F><L><V><R><T><H><E><K><S><R><N><K><N><A><R><Q><L><T><W><V><L><L><L><K><A><H><R><A><A><G><C><L><T><S><L><G><S><A><L><F><A><L><G><T><A><V><R><R><R><I><A><A><G><R><T><D><I><E><I><S><S><S><G...
Probable beta-1,4-glucan synthase rather involved in the synthesis of the xyloglucan backbone than cellulose. Seems to work simultaneously with xyloglucan 6-xylosyltransferase. Xyloglucan is a noncellulosic polysaccharides of plant cell wall and consists of a glucan backbone substituted by xylose, galactose and fucose....
Q9ZQB9
P45097
QUEE_HAEIN
Queuosine biosynthesis protein QueE
Haemophilus
<M><L><M><E><K><Y><H><D><F><E><P><N><F><N><I><V><E><I><F><E><S><L><Q><G><E><G><F><N><T><G><M><P><S><V><F><V><R><F><G><K><C><N><L><D><C><P><W><C><D><T><P><Y><N><N><F><K><R><W><S><V><S><Q><I><L><E><K><V><R><S><F><S><S><K><N><I><I><I><T><G><G><E><P><T><I><V><P><K><I><E><Y><L><L><E><Q><F><K><S><D><G><Y><F><L><A><I><E><T><N...
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.<BOP>
P45097
P50218
IDHC_TOBAC
Oxalosuccinate decarboxylase
Nicotiana
<M><T><F><D><K><I><K><V><E><N><P><I><V><E><M><D><G><D><E><M><T><R><V><I><W><K><S><I><K><D><K><L><I><C><P><F><L><E><L><D><I><K><Y><F><D><L><G><L><P><H><R><D><A><T><D><D><K><V><T><V><E><S><A><E><A><T><Q><K><Y><N><V><A><I><K><C><A><T><I><T><P><D><E><A><R><V><K><E><F><N><L><K><S><M><W><R><S><P><N><G><T><I><R><N><I><L><N><G...
May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway.<BOP>
P50218
P0CS52
TRM82_CRYNJ
Transfer RNA methyltransferase 82
Cryptococcus neoformans species complex
<M><A><L><H><C><P><P><T><A><L><A><T><S><S><T><S><L><F><I><A><A><G><P><A><L><H><V><F><N><P><S><T><S><T><F><A><S><C><A><A><D><G><T><G><G><L><I><R><L><L><A><V><R><E><D><G><E><V><A><A><T><L><G><E><D><K><Q><L><A><V><W><D><I><Q><H><D><R><P><Q><F><R><H><T><R><T><V><V><K><K><G><S><C><L><S><F><A><K><D><G><S><I><I><L><T><D><K><V...
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.<BOP>
P0CS52
Q13F13
Y086_RHOPS
Nucleoid-associated protein RPD_0086
Rhodopseudomonas
<M><A><D><F><L><G><M><M><K><Q><A><A><Q><L><Q><S><K><M><K><A><M><Q><A><E><L><D><Q><I><E><V><E><G><S><S><G><G><G><L><V><Q><V><R><M><S><A><K><M><E><V><R><G><V><S><I><D><P><S><L><L><K><P><D><E><G><G><V><L><E><D><L><L><V><A><A><H><A><D><A><H><R><K><A><E><A><A><M><Q><E><K><M><Q><A><L><T><G><G><L><G><L><P><P><G><L><G><L><G>
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP>
Q13F13
O93233
PLIB_GLOBS
Phospholipase A2 inhibitor
Gloydius
<M><K><S><S><V><P><S><L><L><I><A><C><L><V><M><S><L><N><S><Y><T><Q><Q><V><L><Y><C><P><P><T><P><A><P><E><N><V><T><E><F><V><C><N><S><P><S><L><H><E><F><P><T><G><F><P><A><R><A><K><M><I><S><V><E><F><T><Q><V><S><S><L><G><V><E><A><L><Q><G><L><P><N><L><Q><E><L><H><L><S><N><N><R><L><K><T><L><P><S><G><L><F><R><N><L><P><Q><L><H><T...
Inhibits the enzymatic activity of the basic phospholipase A2 (PLA2).<BOP>
O93233
B0JWU7
ATPL_MICAN
Lipid-binding protein
Microcystis
<M><N><P><T><V><A><A><A><S><V><I><A><A><A><L><A><V><G><L><A><A><I><G><P><G><V><G><Q><G><T><A><S><G><E><A><V><S><G><I><A><R><Q><P><E><A><E><G><R><I><R><G><T><L><L><L><S><L><A><F><M><E><S><L><T><I><Y><G><L><V><I><A><L><V><L><L><F><A><N><P><F><A>
Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.<BOP>
B0JWU7
C1D973
Y2029_LARHH
Nucleotide-binding protein LHK_02029
Laribacter
<M><Q><L><I><L><I><S><G><L><A><G><S><G><K><S><I><A><L><N><V><L><E><D><S><G><Y><S><C><I><D><N><L><P><L><T><L><V><P><D><T><V><E><R><L><A><P><L><G><Y><E><Q><L><A><I><S><I><D><T><R><D><G><A><S><R><L><L><E><V><I><H><A><L><E><T><A><G><H><N><V><R><F><L><F><L><E><A><R><T><D><T><L><I><R><R><F><S><E><T><R><R><R><H><P><L><S><R><T...
Displays ATPase and GTPase activities.<BOP>
C1D973
Q864F6
MSHR_EULFU
Melanocortin receptor 1
Eulemur
<M><P><A><Q><G><S><Q><R><G><L><L><G><A><V><N><F><T><P><T><A><T><P><H><L><R><P><A><A><N><Q><T><G><P><Q><C><L><E><V><S><V><P><D><G><L><F><L><C><L><G><L><V><S><L><V><E><N><T><L><V><V><A><A><I><A><K><N><R><N><L><H><S><P><M><Y><C><F><I><C><C><L><A><L><S><D><L><L><V><S><V><S><N><L><L><E><T><A><V><L><L><L><L><E><V><G><A><L><A...
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.<BOP>
Q864F6
A5FA76
TRPA_FLAJ1
Tryptophan synthase alpha chain
Flavobacterium
<M><N><R><I><T><Q><K><L><Q><E><D><K><K><I><L><S><I><Y><F><S><A><G><Y><P><N><L><N><D><T><V><Q><I><I><Q><D><L><E><K><N><G><V><D><L><I><E><I><G><L><P><F><S><D><P><L><A><D><G><P><T><I><Q><A><S><S><T><Q><A><L><H><N><G><M><T><T><Q><I><L><F><D><Q><L><Q><N><I><R><E><S><V><K><I><P><L><I><I><M><G><Y><F><N><P><M><L><Q><Y><G><V><E...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
A5FA76
Q1KXU9
PSAI_HELAN
Photosystem I reaction center subunit VIII
Helianthus
<M><T><T><L><N><F><P><S><V><L><V><P><L><V><G><L><V><F><P><A><I><A><M><A><S><L><F><L><H><V><Q><K><N><K><I><V>
May help in the organization of the PsaL subunit.<BOP>
Q1KXU9
Q2NQN1
RS17_SODGM
30S ribosomal protein S17
Sodalis
<M><S><D><K><I><R><T><L><Q><G><R><V><V><S><D><K><M><E><K><S><I><V><V><A><I><E><R><F><V><K><H><P><I><Y><G><K><F><I><K><R><T><T><K><L><H><V><H><D><E><N><N><D><S><N><I><G><D><I><V><E><I><S><E><C><R><P><I><S><K><T><K><S><W><T><L><V><R><V><V><E><K><A><I><L>
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.<BOP>
Q2NQN1
A3CN43
DAPA_STRSV
4-hydroxy-tetrahydrodipicolinate synthase
Streptococcus
<M><A><Y><A><D><L><K><N><C><K><I><I><T><A><F><I><T><P><F><H><E><D><G><S><I><N><F><E><A><I><P><D><L><I><E><H><L><L><A><H><H><T><D><G><I><L><L><A><G><T><T><A><E><S><P><T><L><T><H><D><E><E><L><E><L><F><A><A><V><Q><K><V><V><K><G><R><V><P><L><I><A><G><V><G><T><N><E><T><R><D><S><I><E><F><V><K><E><V><D><E><F><G><G><F><A><A><G...
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).<BOP>
A3CN43
A6NI79
CCD69_HUMAN
Coiled-coil domain-containing protein 69
Homo
<M><G><C><R><H><S><R><L><S><S><C><K><P><P><K><K><K><R><Q><E><P><E><P><E><Q><P><P><R><P><E><P><H><E><L><G><P><L><N><G><D><T><A><I><T><V><Q><L><C><A><S><E><E><A><E><R><H><Q><K><D><I><T><R><I><L><Q><Q><H><E><E><E><K><K><K><W><A><Q><Q><V><E><K><E><R><E><L><E><L><R><D><R><L><D><E><Q><Q><R><V><L><E><G><K><N><E><E><A><L><Q><V...
May act as a scaffold to regulate the recruitment and assembly of spindle midzone components. Required for the localization of AURKB and PLK1 to the spindle midzone.<BOP>
A6NI79
Q61845
MEIG1_MOUSE
Protein expressed in male leptotene and zygotene spermatocytes 278
Mus
<M><A><T><S><D><V><K><P><K><S><I><S><R><A><K><K><W><S><E><E><I><E><N><L><Y><R><F><Q><Q><A><G><Y><R><D><E><I><E><Y><K><Q><V><K><Q><V><A><M><V><D><R><W><P><E><T><G><Y><V><K><K><L><Q><R><R><D><N><T><F><F><Y><Y><N><K><E><R><E><C><E><D><K><E><V><H><K><V><K><V><Y><V><Y>
Essential for spermiogenesis.<BOP>
Q61845
P07902
GALT_HUMAN
UDP-glucose--hexose-1-phosphate uridylyltransferase
Homo
<M><S><R><S><G><T><D><P><Q><Q><R><Q><Q><A><S><E><A><D><A><A><A><A><T><F><R><A><N><D><H><Q><H><I><R><Y><N><P><L><Q><D><E><W><V><L><V><S><A><H><R><M><K><R><P><W><Q><G><Q><V><E><P><Q><L><L><K><T><V><P><R><H><D><P><L><N><P><L><C><P><G><A><I><R><A><N><G><E><V><N><P><Q><Y><D><S><T><F><L><F><D><N><D><F><P><A><L><Q><P><D><A><P...
Plays an important role in galactose metabolism.<BOP>
P07902
P31204
TRPA_ANTSP
Tryptophan synthase alpha chain
unclassified Antithamnion
<M><N><I><I><S><E><S><L><R><S><H><P><N><S><C><A><L><I><P><F><I><T><A><G><Y><P><D><I><N><T><T><I><Q><A><L><Y><E><L><D><S><Q><G><A><D><I><I><E><L><G><I><P><Y><S><D><A><L><A><D><G><S><V><I><Q><H><S><S><L><I><A><L><Q><G><G><T><Y><I><D><Q><V><L><H><I><L><E><V><V><S><T><K><L><N><T><P><I><I><I><L><P><Y><Y><N><P><I><L><K><R><G...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
P31204
Q5WGQ3
MGSA_ALKCK
Methylglyoxal synthase
Alkalihalobacillus
<M><K><I><A><L><I><A><H><D><K><K><K><Q><E><L><V><D><F><C><V><A><Y><E><P><I><L><K><E><H><E><L><Y><A><T><G><T><T><G><T><R><I><M><E><A><T><E><L><V><V><T><R><F><K><S><G><P><L><G><G><D><Q><Q><I><G><A><L><V><A><E><N><Q><F><D><L><I><L><F><M><R><D><P><L><T><A><Q><P><H><E><P><D><V><T><A><L><I><R><L><C><D><V><Q><S><V><P><L><A><T...
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.<BOP>
Q5WGQ3
B8CW78
PNP_HALOH
Polynucleotide phosphorylase
Halothermothrix
<M><H><K><D><W><T><I><D><V><A><G><G><K><M><K><F><E><T><G><K><Y><A><K><Q><A><N><G><S><V><V><A><R><Y><G><D><T><T><V><L><V><T><A><T><M><S><E><P><R><E><G><I><D><Y><F><P><L><M><V><N><Y><E><E><R><V><Y><A><I><G><K><I><P><G><S><I><T><R><R><E><G><R><P><R><D><V><A><T><L><A><A><R><L><I><D><R><P><L><R><P><L><F><P><E><G><F><R><H><D...
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.<BOP>
B8CW78
Q38870
CDPK2_ARATH
Calmodulin-domain protein kinase CDPK isoform 2
Arabidopsis
<M><G><N><A><C><V><G><P><N><I><S><G><N><G><F><L><Q><T><V><T><A><A><M><W><R><P><R><I><G><A><E><Q><A><S><S><S><S><H><G><N><G><Q><V><S><K><E><A><A><S><E><P><A><T><D><Q><V><Q><N><K><P><P><E><P><I><T><M><P><S><S><K><T><N><P><E><T><K><L><K><P><D><L><E><I><Q><P><E><E><K><K><E><K><V><L><A><E><E><T><K><Q><K><V><V><P><E><E><S><K...
May play a role in signal transduction pathways that involve calcium as a second messenger.<BOP>
Q38870
P18970
HBA_AILME
Hemopressin
Ailuropoda
<M><V><L><S><P><A><D><K><T><N><V><K><A><T><W><D><K><I><G><G><H><A><G><E><Y><G><G><E><A><L><E><R><T><F><A><S><F><P><T><T><K><T><Y><F><P><H><F><D><L><S><P><G><S><A><Q><V><K><A><H><G><K><K><V><A><D><A><L><T><T><A><V><G><H><L><D><D><L><P><G><A><L><S><A><L><S><D><L><H><A><H><K><L><R><V><D><P><V><N><F><K><L><L><S><H><C><L><L...
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.<BOP>
P18970
Q8VHL0
UT1_MOUSE
Urea transporter, erythrocyte
Mus
<M><E><D><S><P><T><M><V><K><V><D><R><G><E><N><Q><I><L><S><C><R><G><R><R><C><G><F><K><V><L><G><Y><V><T><G><D><M><K><E><F><A><N><W><L><K><D><K><P><V><V><L><Q><F><M><D><W><I><L><R><G><I><S><Q><V><V><F><V><S><N><P><I><S><G><I><L><I><L><V><G><L><L><V><Q><N><P><W><W><A><L><C><G><C><V><G><T><V><V><S><T><L><T><A><L><L><L><S><Q...
Mediates the transport of urea driven by a concentration gradient across the cell membranes of erythrocytes and the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism . Facilitates water transport in erythrocytes .<BOP>
Q8VHL0
Q7VC41
TPIS_PROMA
Triose-phosphate isomerase
Prochlorococcus
<M><R><K><T><V><I><A><G><N><W><K><M><H><M><T><C><S><S><A><K><E><Y><I><D><K><F><I><P><F><S><K><E><F><P><S><D><R><H><V><V><I><A><P><P><F><T><A><I><S><T><L><A><S><L><L><Q><G><T><N><I><Q><L><S><S><Q><N><V><H><W><E><D><T><G><A><F><T><A><E><I><S><P><S><M><L><L><E><H><D><V><R><Y><A><I><V><G><H><S><E><P><R><K><Y><F><S><E><S><D...
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP>
Q7VC41
Q8U4A5
VATB_PYRFU
V-ATPase subunit B
Pyrococcus
<M><A><K><E><Y><S><T><I><S><R><I><Y><G><P><L><M><I><V><E><G><V><K><G><V><A><Y><G><E><V><V><E><I><E><T><E><W><G><E><K><R><K><G><Q><V><L><D><A><R><E><N><L><A><I><V><Q><V><F><E><G><T><R><D><L><D><I><K><T><T><R><V><R><F><T><G><E><T><L><K><V><P><V><S><M><D><M><L><G><R><I><F><N><G><I><G><K><P><I><D><G><G><P><E><I><I><P><E><D...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.<BOP>
Q8U4A5
Q9VZI3
UN112_DROME
Fermitin-1
Sophophora
<M><I><H><V><G><E><N><T><W><N><L><R><I><L><I><T><D><L><Q><V><E><K><T><L><R><V><K><G><D><Q><H><I><G><G><V><M><L><N><L><V><D><P><E><L><P><K><D><W><S><D><H><A><L><W><W><P><A><K><N><I><W><L><T><R><T><R><S><T><L><D><Q><A><G><V><Q><S><D><S><F><L><H><F><T><P><M><H><K><T><L><R><V><Q><M><P><D><L><R><Y><L><D><Y><R><V><N><F><S><A...
Probably involved in cell adhesion.<BOP>
Q9VZI3
Q9LKN0
CHMO_ATRHO
Choline monooxygenase, chloroplastic
Atriplex
<M><A><A><S><A><T><T><M><L><L><K><Y><P><T><T><V><C><G><I><P><N><S><S><A><N><N><S><T><D><P><S><N><N><I><V><Q><I><P><Q><T><T><T><T><N><S><P><L><L><K><F><R><T><P><N><K><P><V><N><A><V><A><A><P><A><F><P><S><V><T><T><T><T><T><T><T><P><S><S><I><Q><S><L><V><K><D><F><D><P><L><V><P><A><E><D><A><L><T><P><P><S><S><W><Y><T><E><P><A...
Catalyzes the first step of the osmoprotectant glycine betaine synthesis.<BOP>
Q9LKN0
Q4JAI6
PCNA1_SULAC
Proliferating cell nuclear antigen homolog 1
Sulfolobus
<M><R><I><V><Y><D><D><V><R><D><L><K><N><I><V><E><T><L><T><K><F><I><D><E><G><L><F><E><I><G><Q><D><G><I><R><L><V><A><V><D><K><A><H><V><S><L><I><N><I><E><L><Y><K><E><L><F><K><E><Y><E><V><E><D><E><F><K><F><G><F><N><S><Q><Y><L><A><K><I><L><S><I><A><K><R><K><E><E><I><S><I><E><S><D><S><P><E><R><V><K><I><T><L><G><G><A><L><N><R...
Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.<BOP>
Q4JAI6
A9WKM8
METXA_CHLAA
Homoserine transacetylase
Chloroflexus
<M><E><A><I><V><Q><A><P><T><P><E><G><V><G><I><V><R><T><Q><R><M><H><W><T><T><P><L><T><L><T><S><G><A><T><L><G><P><I><T><L><A><Y><E><T><Y><G><E><L><A><P><D><R><S><N><A><I><L><I><L><H><A><L><S><G><D><A><H><A><A><G><F><H><S><P><T><D><R><K><P><G><W><W><D><A><M><I><G><P><G><R><P><F><D><T><N><R><Y><F><V><I><C><S><N><V><I><G><G...
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.<BOP>
A9WKM8
A1TVP2
1A1D_ACIAC
1-aminocyclopropane-1-carboxylate deaminase
Acidovorax
<M><N><L><Q><K><F><P><R><H><A><L><T><F><G><P><T><P><I><H><P><L><K><R><L><S><A><H><L><G><G><K><V><E><L><Y><A><K><R><E><D><C><N><S><G><L><A><F><G><G><N><K><T><R><K><L><E><Y><L><I><P><E><A><I><E><G><G><Y><D><T><L><V><S><I><G><G><I><Q><S><N><Q><T><R><Q><V><A><A><V><A><A><H><L><G><M><K><C><V><L><V><Q><E><N><W><V><N><Y><S><D...
Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.<BOP>
A1TVP2
Q9CWH1
ZBT8A_MOUSE
Zinc finger and BTB domain-containing protein 8A
Mus
<M><E><I><S><S><H><Q><S><Y><L><L><Q><Q><L><N><E><Q><R><R><Q><D><V><F><C><D><C><S><I><L><V><E><G><K><V><F><K><A><H><R><N><V><L><F><A><S><S><G><Y><F><K><M><L><L><S><Q><N><S><R><E><T><S><Q><P><T><T><A><T><F><Q><T><F><S><P><D><T><F><T><V><I><L><D><F><V><Y><S><G><K><L><S><L><T><G><Q><N><V><I><E><V><M><S><A><A><S><F><L><Q><M...
May be involved in transcriptional regulation.<BOP>
Q9CWH1
Q63DG7
XPT_BACCZ
Xanthine phosphoribosyltransferase
Bacillus cereus group
<M><K><V><L><Q><E><K><I><L><N><E><G><K><V><L><S><G><D><V><L><K><V><D><A><F><L><N><H><Q><I><D><P><V><L><M><Q><E><I><G><K><E><F><A><K><R><F><K><E><E><N><I><T><K><I><V><T><I><E><S><S><G><I><A><P><A><V><M><A><A><L><E><L><G><V><K><V><I><F><A><R><K><R><K><S><L><T><L><Q><D><N><M><Y><V><A><S><V><Y><S><F><T><K><Q><E><T><N><E><I...
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP>
Q63DG7
Q3MFR5
CLPP1_TRIV2
Endopeptidase Clp 1
Trichormus
<M><T><I><P><I><V><I><E><Q><S><G><R><G><E><R><A><F><D><I><Y><S><R><L><L><R><E><R><I><I><F><L><G><Q><Q><V><D><S><N><L><A><N><L><I><V><A><Q><L><L><F><L><D><A><E><D><P><E><K><D><I><Y><L><Y><I><N><S><P><G><G><S><V><T><A><G><M><G><I><F><D><T><M><K><H><I><R><P><D><V><C><T><I><C><T><G><L><A><A><S><M><G><A><F><L><L><S><A><G><T...
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.<BOP>
Q3MFR5
Q1IGC6
METXS_PSEE4
Homoserine transsuccinylase
Pseudomonas
<M><S><T><V><L><P><E><D><S><V><G><L><V><T><P><Q><I><A><R><F><D><E><P><L><A><L><A><C><G><R><S><L><A><A><Y><E><L><I><Y><E><T><Y><G><E><L><N><A><S><A><S><N><A><V><L><I><C><H><A><L><S><G><H><H><H><A><A><G><Y><H><A><A><T><D><R><K><P><G><W><W><D><S><C><I><G><P><G><K><P><I><D><T><N><R><F><F><V><V><S><L><N><N><L><G><G><C><N><G...
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.<BOP>
Q1IGC6
Q8TSY1
RNFE_METAC
Rnf electron transport complex subunit E
Methanosarcina
<M><Y><P><H><R><R><A><D><M><N><P><I><S><E><F><I><R><G><I><T><K><D><N><P><T><F><G><L><V><L><G><L><C><P><T><L><A><V><T><T><S><V><E><N><G><I><G><M><A><M><G><T><L><F><V><L><V><G><S><N><M><M><V><S><A><I><R><K><G><I><P><G><T><V><R><L><P><V><E><I><I><V><I><A><T><F><V><T><I><V><D><M><V><M><E><A><F><T><P><D><L><Y><T><S><L><G><V...
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Catalyzes Na(+) transport, most probably coupled to electron transfer from reduced ferredoxin to methanophenazine and heterodisulfide reductase. Involved in heterodisulfide reduction during methanogenesis fro...
Q8TSY1
Q8VEB3
MACIR_MOUSE
Macrophage immunometabolism regulator
Mus
<M><E><V><D><I><N><G><D><S><R><S><T><L><T><T><L><P><L><P><V><A><E><G><S><S><P><G><K><A><E><A><E><K><P><R><C><S><S><T><P><C><S><P><M><R><R><T><V><S><G><Y><Q><I><L><H><M><D><S><N><Y><L><V><G><F><T><T><G><E><E><L><L><K><L><A><Q><K><C><T><G><G><E><D><S><K><G><E><A><M><P><A><L><R><A><K><Q><L><D><T><G><L><A><R><S><S><R><L><Y...
Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages. The regulation of macrophage function is, due at least in part, to its ability to inhibit glycolysis. May also play a role in trafficking of proteins via its interaction with UNC119 and ...
Q8VEB3
Q9B5Q1
CYB_SYLGR
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Sylvicapra
<M><T><N><I><R><K><T><H><P><L><L><K><I><V><N><N><A><F><I><D><L><P><A><P><S><N><I><S><S><W><W><N><F><G><S><L><L><G><I><C><L><I><L><Q><I><L><T><G><L><F><L><A><M><H><Y><T><A><D><T><T><T><A><F><S><S><V><T><H><I><C><R><D><V><N><Y><G><W><I><I><R><Y><M><H><A><N><G><A><S><M><F><F><I><C><L><F><M><H><V><G><R><G><L><Y><Y><G><S><Y...
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is...
Q9B5Q1
Q8L9K1
ERF99_ARATH
Ethylene-responsive element-binding factor 13
Arabidopsis
<M><S><S><S><D><S><V><N><N><G><V><N><S><R><M><Y><F><R><N><P><S><F><S><N><V><I><L><N><D><N><W><S><D><L><P><L><S><V><D><D><S><Q><D><M><A><I><Y><N><T><L><R><D><A><V><S><S><G><W><T><P><S><V><P><P><V><T><S><P><A><E><E><N><K><P><P><A><T><K><A><S><G><S><H><A><P><R><Q><K><G><M><Q><Y><R><G><V><R><R><R><P><W><G><K><F><A><A><E><I...
Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.<BOP>
Q8L9K1
Q9ZT17
AGP3_ARATH
Classical arabinogalactan protein 3
Arabidopsis
<M><A><L><K><T><L><Q><A><L><I><F><L><G><L><F><A><A><S><C><L><A><Q><A><P><A><P><A><P><I><T><F><L><P><P><V><E><S><P><S><P><V><V><T><P><T><A><E><P><P><A><P><V><A><S><P><P><I><P><A><N><E><P><T><P><V><P><T><T><P><P><T><V><S><P><P><T><T><S><P><T><T><S><P><V><A><S><P><P><K><P><Y><A><L><A><P><G><P><S><G><P><T><P><A><P><A><P><A...
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death.<BOP>
Q9ZT17
P53591
SUCD_COXBU
Succinyl-CoA synthetase subunit alpha
Coxiella
<M><S><I><L><I><D><K><E><T><R><V><L><C><Q><G><F><T><G><K><Q><G><T><F><H><S><E><Q><A><I><E><Y><G><T><Q><M><V><G><G><V><T><P><G><K><G><G><Q><S><H><L><G><L><P><I><F><N><S><V><H><E><A><V><E><E><T><S><A><D><A><T><M><I><F><V><P><A><P><F><C><K><D><S><I><I><E><A><V><D><A><G><V><R><L><V><V><C><I><T><E><G><I><P><V><L><D><M><L><E...
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate ...
P53591
P0AA83
CODB_ECOL6
Cytosine permease
Escherichia
<M><S><Q><D><N><N><F><S><Q><G><P><V><P><Q><S><A><R><K><G><V><L><A><L><T><F><V><M><L><G><L><T><F><F><S><A><S><M><W><T><G><G><T><L><G><T><G><L><S><Y><H><D><F><F><L><A><V><L><I><G><N><L><L><L><G><I><Y><T><S><F><L><G><Y><I><G><A><K><T><G><L><T><T><H><L><L><A><R><F><S><F><G><V><K><G><S><W><L><P><S><L><L><L><G><G><T><Q><V><G...
Required for cytosine transport into the cell.<BOP>
P0AA83
C1DCA5
NUOC_LARHH
NDH-1 subunit C
Laribacter
<M><A><S><S><L><D><A><L><K><A><R><V><E><S><L><L><G><D><H><L><E><S><A><T><I><D><R><G><E><L><T><I><V><C><S><A><S><S><I><A><V><S><C><Q><L><L><R><D><Q><A><G><F><D><Q><C><I><D><L><C><G><M><D><Y><S><T><Y><R><D><G><L><H><D><R><P><R><F><A><V><V><L><H><L><M><S><V><Q><N><N><Q><R><L><R><V><R><F><F><A><P><D><D><D><F><P><V><V><P><S...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
C1DCA5
Q2NUV8
LIPA_SODGM
Sulfur insertion protein LipA
Sodalis
<M><S><K><P><I><Q><M><E><R><G><V><K><Y><R><D><A><D><K><M><A><L><I><P><I><K><T><V><A><V><E><R><Q><E><I><L><R><K><P><S><W><M><K><I><K><L><P><A><D><S><T><R><I><Q><G><I><K><V><A><M><R><K><N><G><L><H><S><V><C><E><E><A><S><C><P><N><L><A><E><C><F><N><H><G><T><A><T><F><M><I><L><G><A><I><C><T><R><R><C><P><F><C><D><V><A><H><G><R...
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP>
Q2NUV8
Q0AUC8
ATPL_SYNWW
Lipid-binding protein
Syntrophomonas
<M><G><V><A><L><G><A><G><L><A><V><S><I><A><G><I><G><G><G><I><G><M><G><I><A><G><G><K><A><F><E><A><I><A><R><Q><P><E><V><G><G><D><V><R><T><L><L><F><I><T><L><A><F><I><E><T><L><T><I><Y><G><L><L><I><A><F><M><L><V><G><K><A>
Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.<BOP>
Q0AUC8
Q6FYZ6
GCSH_BARQU
Glycine cleavage system H protein
Bartonella
<M><S><Q><I><Y><F><T><Q><D><H><E><W><L><S><V><E><G><Q><V><V><T><V><G><I><T><N><Y><A><Q><E><Q><L><G><D><L><V><F><V><D><L><P><Q><S><G><T><K><L><S><K><G><D><A><A><A><V><V><E><S><V><K><A><A><S><D><V><Y><A><P><L><D><G><E><V><V><E><I><N><E><A><L><A><N><S><P><E><L><V><N><Q><K><A><E><K><E><G><W><L><W><K><M><T><V><Q><D><E><T><Q...
The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.<BOP>
Q6FYZ6
A6KYS6
LUXS_PHOV8
Autoinducer-2 production protein LuxS
Phocaeicola
<M><K><T><I><P><S><F><T><I><D><H><I><R><L><L><R><G><I><Y><V><S><R><K><D><E><V><G><G><E><T><V><T><T><F><D><I><R><M><K><E><P><N><R><E><P><A><L><G><Q><G><A><L><H><T><I><E><H><L><A><A><T><Y><L><R><N><H><P><I><W><S><D><K><I><V><Y><W><G><P><M><G><C><L><T><G><N><Y><L><L><M><K><G><D><L><K><S><E><D><I><V><E><L><M><Q><E><T><F><R...
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhom...
A6KYS6
A4SVI8
KAD_POLAQ
Adenylate monophosphate kinase
Polynucleobacter
<M><R><L><I><L><L><G><A><P><G><A><G><K><G><T><Q><A><Q><F><I><C><E><K><F><A><I><P><Q><I><S><T><G><D><M><L><R><A><A><V><K><A><G><T><E><F><G><V><A><A><K><K><I><M><D><A><G><G><L><V><S><D><D><I><I><I><G><L><V><K><D><R><L><T><Q><P><D><C><S><K><G><Y><L><F><D><G><F><P><R><T><I><P><Q><A><Q><A><M><K><D><A><G><V><P><I><D><Y><V><L...
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.<BOP>
A4SVI8
A7FUX9
MSRA_CLOB1
Peptide-methionine (S)-S-oxide reductase
Clostridium
<M><K><E><I><V><L><A><G><G><C><F><W><G><V><E><E><Y><M><S><R><I><E><G><I><V><E><T><K><V><G><Y><A><N><G><I><K><E><N><P><S><Y><E><E><V><C><S><G><V><T><G><H><A><E><A><C><Y><I><K><Y><D><E><S><I><I><S><L><E><E><L><L><N><K><F><W><S><I><I><D><P><T><V><L><N><K><Q><G><N><D><R><G><T><Q><Y><R><T><G><I><F><Y><L><D><E><K><D><L><N><V...
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.<BOP>
A7FUX9
Q6G1A4
PURA_BARQU
IMP--aspartate ligase
Bartonella
<M><A><N><V><V><V><V><G><T><Q><W><G><D><E><G><K><G><K><I><V><D><W><L><S><E><R><A><D><I><V><V><R><Y><Q><G><G><H><N><A><G><H><T><L><V><V><N><G><V><N><Y><K><L><S><L><L><P><S><G><L><V><R><G><K><L><S><I><I><G><N><G><V><V><V><D><P><H><H><F><V><A><E><L><K><K><L><R><D><Q><G><V><K><I><T><P><E><I><L><R><I><A><E><N><A><P><L><I><L...
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP>
Q6G1A4
Q3YUK4
DSBD_SHISS
Protein-disulfide reductase
Shigella
<M><A><Q><R><I><F><T><L><I><L><L><L><C><S><T><S><V><F><A><G><L><F><D><A><P><G><R><S><H><F><V><P><A><D><Q><A><F><A><F><D><F><Q><Q><N><Q><H><D><L><N><L><T><W><Q><I><K><D><G><Y><Y><L><Y><R><K><Q><I><R><I><T><P><E><H><A><K><I><A><D><V><Q><L><P><Q><G><V><W><H><E><D><E><F><Y><G><K><S><E><I><Y><R><D><R><L><T><L><P><V><T><I><N...
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps.<BOP>
Q3YUK4
Q5XC65
GLYA_STRP6
Serine hydroxymethyltransferase
Streptococcus
<M><I><F><D><K><G><N><V><E><D><F><D><K><E><L><W><D><A><I><H><A><E><E><E><R><Q><E><H><H><I><E><L><I><A><S><E><N><M><V><S><K><A><V><M><A><A><Q><G><S><V><L><T><N><K><Y><A><E><G><Y><P><G><N><R><Y><Y><G><G><T><E><C><V><D><I><V><E><T><L><A><I><E><R><A><K><K><L><F><G><A><A><F><A><N><V><Q><A><H><S><G><S><Q><A><N><A><A><A><Y><M...
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a...
Q5XC65
B8G5S6
RUVB_CHLAD
Holliday junction ATP-dependent DNA helicase RuvB
Chloroflexus
<M><S><A><E><R><L><V><N><P><H><S><D><S><D><D><Q><Q><V><E><K><S><L><R><P><R><T><L><S><E><F><I><G><Q><E><K><V><V><E><Q><L><R><I><A><I><A><A><A><R><G><R><N><E><A><L><D><H><T><L><F><Y><G><P><P><G><L><G><K><T><S><L><A><N><V><V><A><N><E><M><G><A><K><I><K><I><T><S><G><P><A><I><E><R><A><G><D><L><A><A><I><L><T><N><L><Q><P><N><D...
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.<BOP>
B8G5S6
A3QCG6
DER_SHELP
GTP-binding protein EngA
Shewanella
<M><I><P><V><V><A><L><V><G><R><P><N><V><G><K><S><T><L><F><N><R><L><T><R><T><R><D><A><L><V><A><D><Y><P><G><L><T><R><D><R><K><Y><G><R><A><H><L><S><G><Y><E><F><I><V><V><D><T><G><G><I><D><G><T><E><E><G><I><E><T><R><M><A><E><Q><S><L><A><A><I><E><E><A><D><V><V><L><F><L><T><D><A><R><A><G><L><T><A><A><D><E><A><I><A><E><H><L><R...
GTPase that plays an essential role in the late steps of ribosome biogenesis.<BOP>
A3QCG6
Q1H4M0
RS5_METFK
30S ribosomal protein S5
Methylobacillus
<M><A><K><V><E><I><E><Q><Q><Q><T><D><G><L><R><E><K><M><I><G><V><N><R><V><T><K><V><V><K><G><G><R><I><M><S><F><A><A><L><S><V><V><G><D><G><D><G><G><V><G><M><G><K><G><K><A><R><E><V><P><V><A><V><Q><K><A><M><D><E><A><R><R><S><M><I><K><V><S><L><N><N><G><T><L><Y><H><A><V><T><G><V><H><G><A><A><K><V><F><I><Q><P><A><S><E><G><T><G...
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<BOP>
Q1H4M0
Q49KY5
CYF_EUCGG
Cytochrome f
Eucalyptus
<M><Q><T><K><N><T><F><S><W><I><K><K><E><I><I><R><S><I><S><V><S><L><M><I><Y><I><I><A><R><T><S><I><S><N><A><Y><P><I><F><A><Q><Q><G><Y><E><N><P><R><E><A><T><G><R><I><V><C><A><N><C><H><L><A><N><K><P><V><D><I><E><V><P><Q><A><V><L><P><D><T><V><F><E><A><V><V><R><I><P><Y><D><M><Q><V><K><Q><V><L><A><N><G><K><R><G><G><L><N><V><G...
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.<BOP>
Q49KY5
Q5WWT0
SERC_LEGPL
Phosphohydroxythreonine aminotransferase
Legionella
<M><N><S><R><V><F><N><F><G><A><G><P><A><M><L><P><E><E><I><L><K><E><A><Q><E><E><F><L><N><W><R><N><T><G><M><S><I><L><E><I><G><H><R><T><P><E><I><I><S><L><L><S><T><A><E><Q><S><L><R><E><L><L><N><I><P><K><N><Y><H><V><L><F><L><G><G><A><A><R><T><Q><F><A><M><I><P><M><N><L><L><R><P><G><D><D><A><A><Y><F><I><T><G><I><W><S><K><M><A...
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.<BOP>
Q5WWT0
A7I3D6
FABH_CAMHC
3-oxoacyl-[acyl-carrier-protein] synthase III
Campylobacter
<M><K><N><A><A><M><L><S><I><G><A><Y><V><P><P><Y><E><L><S><N><F><D><L><E><K><M><V><E><T><S><D><E><W><I><V><K><R><T><G><I><H><T><R><H><I><A><K><N><E><T><A><G><D><M><A><A><K><A><A><D><L><A><I><S><R><S><G><I><S><K><E><E><I><D><A><I><I><C><A><T><I><T><P><D><F><F><C><M><P><S><T><A><C><I><T><A><E><K><L><G><L><N><K><G><I><T><A...
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-A...
A7I3D6
Q4R3Q1
IF4A3_MACFA
Eukaryotic initiation factor 4A-III, N-terminally processed
Macaca
<M><A><T><T><A><T><M><A><T><S><G><S><A><R><K><R><L><L><K><E><E><D><M><T><K><V><E><F><E><T><S><E><E><V><D><V><T><P><T><F><D><T><M><G><L><R><E><D><L><L><R><G><I><Y><A><Y><G><F><E><K><P><S><A><I><Q><Q><R><A><I><K><Q><I><I><K><G><R><D><V><I><A><Q><S><Q><S><G><T><G><K><T><A><T><F><S><I><S><V><L><Q><C><L><D><I><Q><V><R><E><T...
ATP-dependent RNA helicase. Involved in pre-mRNA splicing as component of the spliceosome. Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic a...
Q4R3Q1
B5BLB2
LEUD_SALPK
Isopropylmalate isomerase
Salmonella
<M><A><E><K><F><T><Q><H><T><G><L><V><V><P><L><D><A><A><N><V><D><T><D><A><I><I><P><K><Q><F><L><Q><K><V><T><R><T><G><F><G><A><H><L><F><N><D><W><R><F><L><D><E><K><G><Q><Q><P><N><P><E><F><V><L><N><F><P><E><Y><Q><G><A><S><I><L><L><A><R><E><N><F><G><C><G><S><S><R><E><H><A><P><W><A><L><T><D><Y><G><F><K><V><V><I><A><P><S><F><A...
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP>
B5BLB2
Q8NBR6
MINY2_HUMAN
Protein FAM63B
Homo
<M><E><S><S><P><E><S><L><Q><P><L><E><H><G><V><A><A><G><P><A><S><G><T><G><S><S><Q><E><G><L><Q><E><T><R><L><A><A><G><D><G><P><G><V><W><A><A><E><T><S><G><G><N><G><L><G><A><A><A><A><R><R><S><L><P><D><S><A><S><P><A><G><S><P><E><V><P><G><P><C><S><S><S><A><G><L><D><L><K><D><S><G><L><E><S><P><A><A><A><E><A><P><L><R><G><Q><Y><K...
Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins . Binds to polyubiquitin chains of different linkage types, including 'Lys-6', 'Lys-11', 'Lys-29', 'Lys-33', 'Lys-48' and 'Lys-63' . May play a regulatory role at the level of protein turnover .<BOP>
Q8NBR6
L0T905
RSEA_MYCTU
Sigma-E anti-sigma factor RseA
Mycobacterium tuberculosis complex
<M><A><D><P><G><S><V><G><H><V><F><R><R><A><F><S><W><L><P><A><Q><F><A><S><Q><S><D><A><P><V><G><A><P><R><Q><F><R><S><T><E><H><L><S><I><E><A><I><A><A><F><V><D><G><E><L><R><M><N><A><H><L><R><A><A><H><H><L><S><L><C><A><Q><C><A><A><E><V><D><D><Q><S><R><A><R><A><A><L><R><D><S><H><P><I><R><I><P><S><T><L><L><G><L><L><S><E><I><P...
An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigE. ECF sigma factors are held in an inactive form by an anti-sigma factor.<BOP>
L0T905
B7GZQ9
QUEF_ACIB3
PreQ(0) reductase
Acinetobacter calcoaceticus/baumannii complex
<M><S><V><E><Q><S><L><L><G><K><E><T><Q><Y><P><T><S><Y><Q><P><D><V><L><F><P><I><A><R><A><Q><S><R><E><K><Y><A><H><I><Q><G><I><T><Q><G><K><D><W><W><H><V><F><E><I><S><W><L><N><A><H><G><I><P><Q><V><A><I><G><R><I><T><L><P><A><S><S><P><N><L><I><E><S><K><S><L><K><L><Y><F><N><S><L><N><F><T><Q><F><D><S><T><Q><S><F><I><E><T><V><E...
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).<BOP>
B7GZQ9
A4WQD9
DDL_CERS5
D-alanylalanine synthetase
Cereibacter
<M><A><G><R><S><G><R><T><F><P><R><V><A><V><L><M><G><G><T><S><S><E><R><E><V><S><L><S><S><G><H><S><C><S><A><A><L><R><D><A><G><Y><E><V><T><E><V><D><A><G><P><D><L><A><R><V><L><A><E><V><Q><P><D><A><V><F><N><A><L><H><G><R><W><G><E><D><G><C><V><Q><G><L><L><E><W><L><R><I><P><Y><T><H><S><G><V><L><A><S><A><L><A><M><D><K><A><R><A...
Cell wall formation.<BOP>
A4WQD9
Q7VUH1
KPRS_BORPE
Phosphoribosyl pyrophosphate synthase
Bordetella
<M><I><F><T><G><T><A><N><T><R><L><A><V><D><V><V><N><H><L><D><M><S><L><G><K><M><T><V><G><R><Y><S><D><G><E><V><M><V><E><I><N><E><N><V><R><G><K><D><V><F><V><L><Q><P><T><C><A><P><T><N><D><N><L><M><E><I><M><V><M><V><D><A><L><R><R><A><S><A><G><R><I><T><A><A><I><P><Y><F><G><Y><A><R><Q><D><R><R><P><R><S><A><R><V><A><I><S><A><K...
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).<BOP>
Q7VUH1
O25150
CMOA_HELPY
Carboxy-S-adenosyl-L-methionine synthase
Helicobacter
<M><K><D><T><L><F><N><E><S><L><N><K><R><F><C><F><D><E><K><V><A><H><V><F><D><D><M><L><E><R><S><I><P><Y><Y><H><E><M><L><N><L><G><A><Y><F><I><A><Q><N><L><K><E><N><I><Y><P><K><S><L><P><K><P><L><I><Y><D><L><G><C><S><T><G><N><F><F><I><A><L><N><R><Q><I><Q><Q><E><I><E><L><V><G><I><D><N><S><M><P><M><L><K><K><A><Q><E><K><L><K><D...
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).<BOP>
O25150
B9DPQ3
PYRR_STACT
Uracil phosphoribosyltransferase
Staphylococcus
<M><S><E><R><I><V><L><D><E><A><A><M><K><R><T><L><M><R><M><A><H><E><I><L><E><Y><N><R><G><T><K><D><L><V><L><L><G><V><K><T><R><G><E><F><L><A><K><S><I><Q><S><K><I><Q><Q><I><E><N><T><T><V><P><T><G><T><I><D><I><T><Q><F><R><D><D><L><E><L><P><T><P><K><I><S><E><K><S><F><V><I><D><V><D><I><T><D><K><V><V><I><I><I><D><D><V><L><Y><T...
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.<BOP>
B9DPQ3
Q16674
MIA_HUMAN
Melanoma inhibitory activity protein
Homo
<M><A><R><S><L><V><C><L><G><V><I><I><L><L><S><A><F><S><G><P><G><V><R><G><G><P><M><P><K><L><A><D><R><K><L><C><A><D><Q><E><C><S><H><P><I><S><M><A><V><A><L><Q><D><Y><M><A><P><D><C><R><F><L><T><I><H><R><G><Q><V><V><Y><V><F><S><K><L><K><G><R><G><R><L><F><W><G><G><S><V><Q><G><D><Y><Y><G><D><L><A><A><R><L><G><Y><F><P><S><S><I...
Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.<BOP>
Q16674
B1ZDN3
LEU1_METPB
Alpha-isopropylmalate synthase
Methylorubrum
<M><A><N><T><T><E><S><A><K><D><R><V><V><I><F><D><T><T><L><R><D><G><E><Q><C><P><G><A><T><M><T><L><D><E><K><L><A><V><A><E><L><L><D><A><M><G><V><D><I><I><E><A><G><F><P><I><A><S><N><G><D><F><E><A><V><S><E><I><A><R><R><T><K><R><A><T><I><A><G><L><A><R><A><I><P><A><D><I><A><R><A><G><E><A><V><R><H><A><K><A><G><R><I><H><T><F><V...
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).<BOP>
B1ZDN3
P00852
ATP6_EMEND
F-ATPase protein 6
Aspergillus subgen. Nidulantes
<M><Y><Q><F><N><F><I><L><S><P><L><D><Q><F><E><I><R><D><L><F><S><L><N><A><N><V><L><G><N><I><H><L><S><I><T><N><I><G><L><Y><L><S><I><G><L><L><L><T><L><G><Y><H><L><L><A><A><N><N><K><I><I><P><N><N><W><S><I><S><Q><E><A><I><Y><A><T><V><H><S><I><V><I><N><Q><L><N><P><T><K><G><Q><L><Y><F><P><F><I><Y><A><L><F><I><F><I><L><V><N><N...
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous ca...
P00852
C6DF35
ARGP_PECCP
HTH-type transcriptional regulator ArgP
Pectobacterium
<M><K><R><P><D><Y><R><T><L><Q><A><L><D><A><V><I><R><E><R><G><F><E><R><A><A><Q><K><L><C><I><T><Q><S><A><V><S><Q><R><I><K><Q><L><E><N><L><F><G><Q><P><L><L><V><R><T><I><P><P><R><P><T><E><Q><G><Q><K><L><L><A><L><L><H><Q><V><E><L><L><E><E><E><W><L><G><N><E><T><N><S><D><I><P><L><L><L><S><L><A><V><N><A><D><S><L><A><T><W><L><L...
Controls the transcription of genes involved in arginine and lysine metabolism.<BOP>
C6DF35
Q2QNM1
MCM7_ORYSJ
Minichromosome maintenance protein 7
Oryza sativa
<M><A><A><T><A><T><K><T><I><D><F><A><A><E><R><A><L><A><K><D><F><L><A><N><F><A><G><P><R><G><E><P><K><Y><L><N><I><L><Q><D><V><A><N><R><K><I><R><A><V><Q><I><E><L><D><D><L><F><H><Y><K><D><A><D><D><E><F><L><Q><R><V><T><E><N><T><K><R><Y><I><G><I><F><A><D><A><I><D><E><L><M><P><E><S><T><E><A><Y><A><V><D><E><D><R><D><I><L><M><T...
Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells.<BOP>
Q2QNM1
Q96M32
KAD7_HUMAN
ATP-AMP transphosphorylase 7
Homo
<M><A><E><E><E><E><T><A><A><L><T><E><K><V><I><R><T><Q><R><V><F><I><N><L><L><D><S><Y><S><S><G><N><I><G><K><F><L><S><N><C><V><V><G><A><S><L><E><E><I><T><E><E><E><E><E><E><D><E><N><K><S><A><M><L><E><A><S><S><T><K><V><K><E><G><T><F><Q><I><V><G><T><L><S><K><P><D><S><P><R><P><D><F><A><V><E><T><Y><S><A><I><S><R><E><D><L><L><M...
Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. Involved in mainta...
Q96M32
Q97QC4
CRCB2_STRPN
Putative fluoride ion transporter CrcB 2
Streptococcus
<M><K><K><E><Q><F><Y><P><L><G><I><F><L><A><A><M><L><G><G><L><V><R><Y><L><V><S><T><W><L><P><A><S><P><D><F><P><W><G><T><L><F><V><N><Y><L><G><I><F><C><L><I><Y><L><V><K><G><Y><L><V><Y><K><G><T><S><K><G><L><I><L><A><L><G><T><G><F><C><G><G><L><T><T><F><S><S><L><M><L><D><T><V><K><L><L><D><T><G><R><Y><L><S><L><I><L><Y><L><L><L...
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.<BOP>
Q97QC4
Q6LUJ8
FTSH_PHOPR
ATP-dependent zinc metalloprotease FtsH
Photobacterium
<M><W><L><Q><V><T><N><C><S><T><L><H><S><S><L><S><Y><C><G><A><N><T><L><S><D><M><A><K><N><L><I><L><W><L><V><I><A><V><V><L><M><S><V><F><Q><S><F><G><P><S><D><S><A><G><R><Q><V><D><Y><T><T><F><V><R><E><I><G><Q><D><Q><I><R><E><A><R><F><N><E><R><E><I><T><V><F><K><R><D><N><T><R><Y><V><T><Y><L><P><V><F><N><D><Q><K><L><L><D><D><L...
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.<BOP>
Q6LUJ8
A9MU86
OTSA_SALPB
UDP-glucose-glucosephosphate glucosyltransferase
Salmonella
<M><S><R><L><V><V><V><S><N><R><I><A><P><P><D><N><K><G><G><A><G><G><L><A><V><G><V><L><G><A><L><K><A><A><G><G><L><W><F><G><W><S><G><E><T><G><N><E><D><E><P><L><K><K><V><T><K><G><N><I><T><W><A><S><F><N><L><S><E><Q><D><Y><E><D><Y><Y><C><Q><F><S><N><A><V><L><W><P><A><F><H><Y><R><L><D><L><V><Q><F><Q><R><P><A><W><E><G><Y><M><R...
Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.<BOP>
A9MU86