accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
Q8TWR5
IF2B_METKA
eIF-2-beta
Methanopyrus
<M><V><E><Y><D><Y><E><E><L><L><E><R><A><Y><E><Q><L><P><E><E><V><L><E><D><R><R><F><E><M><P><K><P><K><V><S><V><E><G><K><T><T><V><I><R><N><F><K><E><I><S><K><K><L><D><R><D><P><E><H><I><T><K><Y><F><L><K><E><L><G><T><A><G><H><V><D><G><G><R><L><I><L><H><G><V><Y><H><P><K><L><V><E><E><E><L><K><N><Y><V><E><E><F><V><L><C><P><E><C...
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.<BOP>
Q8TWR5
B0R9H2
TH11_HALS3
Probable transposase for insertion sequence element ISH11
Halobacterium
<M><S><P><A><T><L><Q><D><D><P><S><V><D><S><F><F><N><V><V><E><T><E><T><L><A><L><F><E><H><L><S><F><E><F><L><E><E><F><D><V><F><A><P><A><E><T><G><R><T><R><D><H><E><P><P><E><L><M><R><G><F><L><H><C><Y><Y><K><D><I><Y><G><I><R><P><V><E><R><E><L><R><N><T><V><V><W><L><S><C><G><F><D><R><P><P><S><R><D><A><V><D><R><F><L><T><D><L><E...
Involved in the transposition of the insertion sequence ISH11.<BOP>
B0R9H2
B8D9H0
RL21_BUCA5
50S ribosomal protein L21
Buchnera
<M><Y><A><V><F><I><S><G><G><K><Q><Y><R><V><V><K><N><Q><I><I><R><L><E><K><L><N><S><P><L><G><T><T><I><E><F><D><K><I><L><M><L><F><D><K><D><S><I><K><I><G><T><P><F><V><E><G><G><T><I><K><A><H><I><Q><N><H><G><R><L><K><K><I><K><I><I><K><F><N><R><R><K><H><Y><K><K><Q><Q><G><H><R><Q><Y><F><T><D><V><K><I><I><D><I><N><S><I><K><G><E...
This protein binds to 23S rRNA in the presence of protein L20.<BOP>
B8D9H0
C5C9T9
RS15_MICLC
30S ribosomal protein S15
Micrococcus
<M><A><L><D><P><A><V><K><Q><Q><I><I><K><E><Y><A><T><H><E><G><D><T><G><S><P><E><V><Q><I><A><V><L><S><R><R><I><K><D><L><T><E><H><L><K><E><H><K><H><D><H><H><T><R><R><G><L><M><G><L><V><G><R><R><R><R><M><L><G><Y><L><Q><N><V><D><I><E><R><Y><R><A><L><I><E><R><L><G><L><R><K>
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.<BOP>
C5C9T9
Q11I83
ILVC_CHESB
Ketol-acid reductoisomerase type I
unclassified Chelativorans
<M><R><V><Y><Y><D><R><D><A><D><L><N><L><I><K><S><K><K><V><A><I><I><G><Y><G><S><Q><G><R><A><H><A><L><N><L><K><D><S><G><A><K><D><L><A><V><A><L><R><P><G><S><A><S><A><K><K><A><E><A><D><G><L><K><V><M><S><V><A><E><A><A><G><W><A><D><L><M><M><M><A><T><P><D><E><L><Q><A><G><I><Y><N><N><E><I><A><P><N><I><R><D><G><A><A><I><A><F><A...
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu...
Q11I83
A8AN88
UBIA_CITK8
4-HB polyprenyltransferase
Citrobacter
<M><E><W><S><L><T><Q><N><K><L><L><A><F><H><R><L><M><R><T><D><K><P><I><G><A><L><L><L><L><W><P><T><L><W><A><L><W><V><A><T><P><G><V><P><Q><L><W><I><L><A><V><F><V><A><G><V><W><L><M><R><A><A><G><C><V><V><N><D><Y><A><D><R><K><F><D><G><H><V><K><R><T><A><N><R><P><L><P><S><G><A><V><T><E><K><E><A><R><T><L><F><V><V><L><V><A><L><S...
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-...
A8AN88
D2Y297
H1624_CYRHA
Peptide F4-19.87
Haplopelma
<M><N><T><V><R><V><T><F><L><L><V><F><V><L><A><V><S><L><G><Q><A><D><K><D><E><N><R><M><E><M><Q><E><K><T><E><Q><G><R><S><Y><L><D><F><A><E><N><L><L><L><Q><K><L><E><E><L><E><A><K><L><L><E><E><D><S><E><E><S><R><N><S><R><Q><K><R><C><I><G><E><G><V><P><C><D><E><N><D><P><R><C><C><S><G><L><V><C><L><K><P><T><L><H><G><I><W><Y><K><S...
Probable ion channel inhibitor.<BOP>
D2Y297
A5EDB2
UREG1_BRASB
Urease accessory protein UreG 1
unclassified Bradyrhizobium
<M><L><H><A><L><R><Q><A><K><A><Q><A><T><A><T><V><A><A><R><V><G><I><G><G><P><V><G><S><G><K><T><A><L><I><E><A><L><I><P><V><L><Q><R><R><G><V><D><F><A><V><V><T><N><D><L><V><T><K><E><D><A><E><R><L><R><R><S><G><L><I><D><P><D><R><V><S><A><V><E><A><G><A><C><P><H><T><V><I><R><E><D><P><T><L><N><I><A><A><G><D><E><L><E><A><R><F><P...
Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP>
A5EDB2
Q818P5
MNTR_BACCR
Manganese transport regulator
Bacillus cereus group
<M><P><T><P><S><M><E><D><Y><I><E><Q><I><Y><L><L><I><D><E><K><G><Y><A><R><V><S><D><I><A><E><A><L><S><V><H><P><S><S><V><T><K><M><V><Q><K><L><D><K><D><E><Y><L><I><Y><E><K><Y><R><G><L><V><L><T><T><K><G><K><K><I><G><E><R><L><V><Y><R><H><D><L><L><E><Q><F><M><R><I><I><G><V><D><E><S><K><I><Y><N><D><V><E><G><I><E><H><H><L><S><W...
Central regulator of manganese homeostasis.<BOP>
Q818P5
A8FKR5
RS12_CAMJ8
30S ribosomal protein S12
Campylobacter
<M><P><T><I><N><Q><L><V><R><K><E><R><K><K><V><L><E><K><S><K><S><P><A><L><K><N><C><P><Q><R><R><G><V><C><T><R><V><Y><T><T><T><P><K><K><P><N><S><A><L><R><K><V><A><K><V><R><L><T><S><G><F><E><V><I><S><Y><I><G><G><E><G><H><N><L><Q><E><H><S><I><V><L><V><R><G><G><R><V><K><D><L><P><G><V><K><Y><H><I><V><R><G><A><L><D><T><A><G><V...
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com...
A8FKR5
B1ZWN7
ATPG_OPITP
F-ATPase gamma subunit
Opitutus
<M><A><S><T><R><D><I><R><R><R><I><K><S><V><K><N><T><R><Q><I><T><K><A><M><E><L><V><A><A><S><K><M><K><K><A><Q><Q><A><A><V><A><G><R><P><Y><A><E><L><M><A><Q><M><L><A><T><L><G><D><R><V><E><E><A><Q><H><P><F><L><V><Q><R><E><V><K><T><R><G><I><I><L><I><T><T><D><K><G><L><A><G><P><L><N><A><N><L><F><K><L><V><T><D><I><Q><S><P><A><K...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP>
B1ZWN7
A4QJZ9
PSBA_ARAHI
Photosystem II Q(B) protein
Arabis
<M><T><A><I><L><E><R><R><E><S><E><S><L><W><G><R><F><C><N><W><I><T><S><T><E><N><R><L><Y><I><G><W><F><G><V><L><M><I><P><T><L><L><T><A><T><S><V><F><I><I><A><F><I><A><A><P><P><V><D><I><D><G><I><R><E><P><V><S><G><S><L><L><Y><G><N><N><I><I><S><G><A><I><I><P><T><S><A><A><I><G><L><H><F><Y><P><I><W><E><A><A><S><V><D><E><W><L><Y...
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photoni...
A4QJZ9
B6HV34
ADRF_PENRW
Andrastin A biosynthesis cluster protein F
Penicillium chrysogenum species complex
<M><S><L><L><Q><D><I><V><L><I><I><T><G><S><A><S><G><I><G><L><A><T><A><T><A><A><L><S><Q><G><A><K><I><L><G><V><D><V><S><W><A><P><V><S><L><T><E><H><A><S><Y><K><F><I><Q><A><N><L><T><H><E><A><T><P><K><Q><V><V><E><T><C><I><K><E><F><G><R><I><D><G><L><L><N><I><A><G><I><M><D><Q><N><S><S><V><D><S><L><T><D><D><M><W><E><R><C><I><A...
Short chain dehydrogenase; part of the gene cluster that mediates the biosynthesis of andrastins, meroterpenoid compounds that exhibit inhibitory activity against ras farnesyltransferase, suggesting that they could be promising leads for antitumor agents (Ref.2). The first step of the pathway is the synthesis of 3,5-di...
B6HV34
Q0W1L9
THIM_METAR
4-methyl-5-beta-hydroxyethylthiazole kinase
Methanocella
<M><D><A><R><S><L><S><G><I><L><T><E><V><R><E><K><R><P><L><V><H><H><I><T><N><Y><V><T><V><N><D><C><A><N><V><T><L><C><I><G><A><A><P><V><M><A><H><A><H><D><E><V><A><E><M><V><A><M><A><G><A><L><V><L><N><I><G><T><L><D><H><R><Q><V><E><S><M><L><A><A><G><H><R><A><N><E><L><N><I><P><I><I><L><D><P><V><G><A><G><A><T><R><L><R><T><E><T...
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP>
Q0W1L9
B1JFW2
NANK_YERPY
N-acetyl-D-mannosamine kinase
Yersinia
<M><G><K><G><L><A><L><D><I><G><G><T><K><I><A><A><A><V><V><T><E><S><G><M><L><I><G><R><Q><Q><I><A><T><P><R><G><G><A><G><Q><L><A><A><A><L><E><T><L><I><A><P><Y><R><H><Q><V><D><F><I><A><V><A><S><T><G><I><I><S><G><G><R><L><T><A><L><N><P><A><N><L><G><G><L><A><D><F><P><L><Y><D><C><I><R><S><I><S><D><L><P><C><V><L><L><N><D><G><Q...
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.<BOP>
B1JFW2
P53938
EOS1_YEAST
ER-localized and oxidants sensitive protein 1
Saccharomyces
<M><T><W><I><L><S><T><G><M><G><P><H><E><D><K><Y><A><K><H><E><R><A><T><F><K><K><T><Y><S><S><M><K><T><L><S><L><N><H><L><T><A><K><Q><H><M><L><M><A><L><C><R><D><I><S><L><L><P><P><L><T><Y><I><F><T><S><L><R><K><A><W><R><V><S><M><R><T><S><I><T><L><Y><E><P><Q><S><L><R><D><A><F><T><Y><F><W><Q><K><L><N><S><A><Y><D><N><N><S><S><F...
Involved in oxidative stress resistance and N-glycosylation.<BOP>
P53938
P56168
MT21_BRAJU
Metallothionein-like protein type 2, MT2-4/MT2-25
Brassica
<M><S><C><C><G><G><N><C><G><C><G><S><G><C><K><C><V><G><C><G><G><C><K><M><Y><P><D><L><S><F><S><G><E><T><T><T><T><E><T><L><V><L><G><V><A><P><A><M><N><S><Q><F><E><A><S><G><E><T><F><V><A><E><N><D><A><C><K><C><G><S><D><C><K><C><N><P><C><T><C><K>
Metallothioneins have a high content of cysteine residues that bind various heavy metals.<BOP>
P56168
Q6LWZ4
MTRE_METMP
N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E
Methanococcus
<M><D><P><T><L><I><S><L><G><A><L><A><L><A><G><A><A><A><T><V><S><G><C><A><E><D><L><E><S><D><V><G><S><Q><S><N><P><N><S><Q><V><Q><L><G><P><Q><M><G><N><I><H><R><Y><F><N><K><A><I><S><G><E><P><V><S><Y><G><L><Y><V><A><V><A><G><T><I><A><W><A><L><I><N><A><G><L><N><V><V><L><A><I><I><V><G><A><G><V><A><A><I><V><H><G><A><Y><S><V><S...
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.<BOP>
Q6LWZ4
O82213
VAP31_ARATH
Vesicle-associated protein 3-1, N-terminally processed
Arabidopsis
<M><S><N><N><E><L><L><E><I><E><P><M><Y><L><Q><F><P><F><E><L><K><K><Q><M><S><C><S><L><Y><L><T><N><K><T><D><N><N><V><A><F><K><V><K><T><T><N><R><N><N><Y><C><V><R><P><N><Y><G><L><I><L><P><K><S><T><C><K><V><L><V><T><M><Q><A><Q><K><E><V><P><S><D><M><Q><S><F><E><K><F><M><I><Q><S><V><L><A><S><P><G><V><T><A><K><E><V><T><R><E><M...
May play a role in vesicle trafficking.<BOP>
O82213
Q7Z4L9
PPR42_HUMAN
Leucine-rich repeat-containing protein 67
Homo
<M><V><R><L><T><L><D><L><I><A><R><N><S><N><L><K><P><R><K><E><E><T><I><S><Q><C><L><K><K><I><T><H><I><N><F><S><D><K><N><I><D><A><I><E><D><L><S><L><C><K><N><L><S><V><L><Y><L><Y><D><N><C><I><S><Q><I><T><N><L><N><Y><A><T><N><L><T><H><L><Y><L><Q><N><N><C><I><S><C><I><E><N><L><R><S><L><K><K><L><E><K><L><Y><L><G><G><N><Y><I><A...
Regulates phosphatase activity of protein phosphatase 1 (PP1) complexes in the testis.<BOP>
Q7Z4L9
Q7VN63
TATA_HAEDU
Sec-independent protein translocase protein TatA
Haemophilus
<M><G><G><I><S><I><W><Q><L><L><I><I><V><A><I><I><V><L><L><F><G><T><K><K><L><R><T><L><G><T><D><L><G><E><S><V><K><G><F><K><K><A><M><A><E><D><K><S><Q><D><A><N><F><D><K><V><E><A><K><E><S><T><S><T><T><E><K><T><K><E><K><E><Q><A>
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP>
Q7VN63
A3PK84
METAA_CERS1
Homoserine transacetylase
Cereibacter
<M><P><I><T><L><P><A><T><L><P><A><F><D><V><L><T><H><E><G><V><M><V><M><T><P><E><R><A><A><R><Q><D><I><R><P><L><R><I><G><L><L><N><L><M><P><K><K><I><Q><T><E><N><Q><F><A><R><L><I><G><A><T><P><L><Q><I><D><F><Q><L><I><R><M><T><E><H><Q><T><K><N><T><A><A><E><H><M><E><A><F><Y><R><P><F><Q><E><V><K><H><E><K><F><D><G><L><I><I><T><G...
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.<BOP>
A3PK84
A9L591
RLMKL_SHEB9
rRNA (guanine-N(7)-)-methyltransferase RlmK
Shewanella
<M><L><N><F><F><A><A><A><P><K><G><F><E><Y><S><L><A><Q><E><L><T><E><F><G><A><T><E><V><K><E><S><V><A><G><V><Y><F><T><A><S><L><A><L><A><Y><R><I><T><L><W><T><R><L><A><S><R><I><V><L><V><I><Y><K><G><S><C><E><S><A><E><Q><L><Y><N><A><A><Y><C><V><D><W><P><A><H><F><S><N><K><S><T><F><S><I><D><F><H><G><T><G><G><F><L><N><N><T><Q><F...
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.<BOP>
A9L591
Q5HM28
ECFA2_STAEQ
Energy-coupling factor transporter ATP-binding protein EcfA2
Staphylococcus
<M><S><I><Q><F><N><Q><V><S><Y><I><Y><Q><Q><G><T><P><Y><E><F><E><A><I><K><N><V><S><L><T><L><E><Q><G><K><Y><Y><A><I><I><G><Q><T><G><S><G><K><S><T><L><I><Q><H><L><N><A><L><L><K><P><T><T><G><S><V><N><I><N><G><L><E><V><T><N><K><T><K><D><K><H><L><R><H><I><R><K><E><V><G><I><V><F><Q><F><P><E><S><Q><L><F><E><D><S><V><E><K><E><I...
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.<BOP>
Q5HM28
Q45W87
OL111_ARAHY
Oleosin Ara h 11.0101
Arachis
<M><A><E><A><L><Y><Y><G><G><R><Q><R><Q><E><Q><P><R><S><T><Q><L><V><K><A><T><T><A><V><V><A><G><G><S><L><L><I><L><A><G><L><V><L><A><G><T><V><I><G><L><T><T><I><T><P><L><F><V><I><F><S><P><V><L><V><P><A><V><I><T><V><A><L><L><G><L><G><F><L><A><S><G><G><F><G><V><A><A><I><T><V><L><T><W><I><Y><R><Y><V><T><G><K><H><P><P><G><A><N...
May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil. Probably interacts with both lipid and phospholipid moieties of lipid bodies. May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth.<BOP>
Q45W87
A0A455R413
ASCA_ACREG
Ascofuranone/ascochlorin biosynthesis clusters protein A
Acremonium
<M><A><A><K><S><R><S><P><K><R><G><T><S><E><K><T><P><L><V><E><K><E><A><P><Y><Q><P><P><T><K><G><I><L><S><K><L><P><A><S><W><V><P><Y><A><Q><L><I><R><L><E><Q><P><H><G><N><Y><M><I><Y><F><P><H><I><I><G><L><M><Y><A><S><A><I><R><P><T><E><L><S><V><L><G><H><R><A><A><I><F><A><I><W><T><F><L><M><R><G><A><G><C><A><W><N><D><N><V><D><Q...
Prenytransferase; part of the asc-1 gene cluster that mediates the biosynthesis of both ascochlorin and ascofuranone, a strong inhibitor of cyanide-insensitive alternative oxidases and a promising drug candidate against African trypanosomiasis . The first step in the pathway is performed by the non-reducing polyketide ...
A0A455R413
Q65QH0
GLPE_MANSM
Thiosulfate sulfurtransferase GlpE
Basfia
<M><F><K><E><I><T><P><Q><Q><A><W><Q><L><M><I><E><E><N><A><T><L><V><D><I><R><D><E><Q><R><F><T><Y><S><H><A><K><G><A><F><H><L><T><G><Q><S><Y><G><K><F><Q><I><Q><C><D><F><D><D><P><V><I><V><S><C><Y><H><G><I><S><S><R><N><V><A><A><F><L><V><E><Q><G><Y><D><N><I><Y><S><I><I><G><G><F><E><G><W><Q><R><A><G><L><P><I><E><T><A><Y>
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.<BOP>
Q65QH0
Q48UH5
Y517_STRPM
Nucleotide-binding protein M28_Spy0517
Streptococcus
<M><S><D><K><H><I><N><L><V><I><V><T><G><M><S><G><A><G><K><T><V><A><I><Q><S><F><E><D><L><G><Y><F><T><I><D><N><M><P><P><A><L><V><P><K><F><L><E><L><I><E><Q><T><N><E><N><R><R><V><A><L><V><V><D><M><R><S><R><L><F><F><K><E><I><N><S><T><L><D><S><I><E><S><N><P><S><I><D><F><R><I><L><F><L><D><A><T><D><G><E><L><V><S><R><Y><K><E><T...
Displays ATPase and GTPase activities.<BOP>
Q48UH5
Q8A498
IF1_BACTN
Translation initiation factor IF-1
Bacteroides
<M><A><K><Q><S><A><I><E><Q><D><G><V><I><V><E><A><L><S><N><A><M><F><R><V><E><L><E><N><G><H><E><I><T><A><H><I><S><G><K><M><R><M><H><Y><I><K><I><L><P><G><D><K><V><R><V><E><M><S><P><Y><D><L><S><K><G><R><I><V><F><R><Y><K>
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-...
Q8A498
A0A1V0QSE8
ERIJ_HERER
Erinacine biosynthesis cluster protein J
Hericium
<M><S><T><Q><N><Y><H><I><V><A><V><P><P><N><E><W><G><H><M><R><P><M><I><A><F><L><A><R><L><V><A><V><S><L><N><S><V><D><I><T><V><T><L><I><I><A><E><S><A><V><A><K><A><R><T><E><L><S><I><Q><L><A><G><E><G><I><Q><S><A><E><S><R><F><E><V><V><P><T><A><V><H><M><F><W><P><A><D><A><Y><L><P><A><L><K><A><T><Y><A><E><V><I><K><K><K><E><P><D...
UDP-glycosyltransferase; part of the gene cluster that mediates the biosynthesis of erinacines, cyathane-xylosides that show unique biological activities, including leishmanicidal activity, stimulating activity for nerve growth-factor synthesis, and agonistic activity toward the kappa opioid receptor . The geranylgeran...
A0A1V0QSE8
P00296
PLAS_SOLTU
Plastocyanin
Solanum
<L><D><V><L><L><G><G><D><D><G><S><L><A><F><I><P><G><N><F><S><V><S><A><G><E><K><I><T><F><K><N><N><A><G><F><P><H><N><V><V><F><D><E><D><E><I><P><A><G><V><D><A><S><K><I><S><M><A><E><E><D><L><L><N><A><A><G><E><T><Y><S><V><T><L><S><E><K><G><T><Y><T><F><Y><C><A><P><H><Q><G><A><G><M><V><G><K><V><T><V><N>
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.<BOP>
P00296
Q8Y626
TYSY_LISMO
Thymidylate synthase
Listeria
<M><K><Q><Y><L><D><L><E><K><Y><V><L><E><N><G><T><Q><K><G><D><R><T><G><T><G><T><I><S><T><F><G><Y><Q><M><R><F><D><L><Q><E><G><F><P><I><M><T><T><K><R><V><P><F><K><L><V><V><S><E><L><L><W><F><L><H><G><D><T><N><I><R><Y><L><L><Q><H><N><N><N><I><W><N><E><W><A><F><E><R><F><V><K><S><D><D><Y><K><G><E><D><M><T><D><F><G><L><R><A><E...
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell...
Q8Y626
A4SXR0
LEU1_POLAQ
Alpha-isopropylmalate synthase
Polynucleobacter
<M><S><D><K><V><I><I><F><D><T><T><L><R><D><G><E><Q><S><P><G><A><S><M><T><K><D><E><K><V><R><I><A><R><Q><L><E><R><L><K><V><D><V><I><E><A><G><F><A><A><S><S><E><G><D><F><Q><A><I><S><A><V><A><A><A><V><K><D><S><I><V><C><S><L><A><R><A><N><D><K><D><I><T><R><A><A><D><A><L><Q><A><A><N><A><K><R><I><H><A><F><L><A><T><S><P><L><H><M...
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).<BOP>
A4SXR0
B8HGW7
MRAY_PSECP
UDP-MurNAc-pentapeptide phosphotransferase
Pseudarthrobacter
<M><I><A><L><L><I><G><A><G><L><A><L><L><C><A><L><V><G><T><P><L><F><I><R><L><L><V><R><R><G><Y><G><Q><F><I><R><D><D><G><P><T><S><H><H><T><K><R><G><T><P><T><M><G><G><T><V><V><V><A><A><V><L><L><S><Y><G><L><T><H><L><I><M><F><L><M><N><P><D><S><P><G><P><S><A><S><A><L><I><L><L><F><L><M><V><G><M><G><L><V><G><F><L><D><D><F><I><K...
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I...
B8HGW7
P39076
TCPB_YEAST
CCT-beta
Saccharomyces
<M><S><V><Q><I><F><G><D><Q><V><T><E><E><R><A><E><N><A><R><L><S><A><F><V><G><A><I><A><V><G><D><L><V><K><S><T><L><G><P><K><G><M><D><K><L><L><Q><S><A><S><S><N><T><C><M><V><T><N><D><G><A><T><I><L><K><S><I><P><L><D><N><P><A><A><K><V><L><V><N><I><S><K><V><Q><D><D><E><V><G><D><G><T><T><S><V><T><V><L><S><A><E><L><L><R><E><A><E...
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. In yeast may play a role in mitotic spindle formation.<BOP>
P39076
A8GPF2
EFTU_RICAH
Elongation factor Tu
spotted fever group
<M><A><K><A><K><F><E><R><T><K><P><H><V><N><I><G><T><I><G><H><V><D><H><G><K><T><S><L><T><A><A><I><T><T><V><L><A><K><T><G><G><A><K><A><T><A><Y><D><Q><I><D><A><A><P><E><E><K><E><R><G><I><T><I><S><T><A><H><V><E><Y><E><T><K><N><R><H><Y><A><H><V><D><C><P><G><H><A><D><Y><I><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V><V><S...
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP>
A8GPF2
Q8FHG6
GADC_ECOL6
Glutamate/gamma-aminobutyrate antiporter
Escherichia
<M><A><T><S><V><Q><T><G><K><A><K><Q><L><T><L><L><G><F><F><A><I><T><A><S><M><V><M><A><V><Y><E><Y><P><T><F><A><T><S><G><F><S><L><V><F><F><L><L><L><G><G><I><L><W><F><I><P><V><G><L><C><A><A><E><M><A><T><V><D><G><W><E><E><G><G><V><F><A><W><V><S><N><T><L><G><P><R><W><G><F><A><A><I><S><F><G><Y><L><Q><I><A><I><G><F><I><P><M><L...
Involved in glutaminase-dependent acid resistance. Exchanges extracellular glutamate (Glu) for intracellular gamma-aminobutyric acid (GABA) under acidic conditions. The ability to survive the extremely acidic conditions of the stomach is essential for successful colonization of the host by commensal and pathogenic bact...
Q8FHG6
Q26516
PPIE_SCHJA
Rotamase E
Schistosoma
<E><D><V><S><D><D><E><M><R><T><K><K><Q><K><R><N><L><P><R><V><F><F><D><I><R><I><G><N><A><D><R><G><R><I><V><M><E><L><R><S><D><I><V><P><R><T><A><E><N><F><R><A><L><C><T><G><D><R><G><F><G><Y><H><N><C><C><F><H><R><V><I><P><Q><F><M><C><Q><G><G><D><F><V><K><G><D><G><T><G><G><K><S><I><Y><G><R><K><F><D><D><E><N><F><Q><L><R><H><E...
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.<BOP>
Q26516
O19015
BGAL_FELCA
Acid beta-galactosidase
Felis
<M><D><F><P><G><A><A><R><L><L><S><L><L><L><V><P><L><L><L><G><P><A><R><G><L><R><N><A><S><Q><R><T><F><K><I><D><Y><G><H><N><R><F><L><K><D><G><Q><P><F><R><Y><I><S><G><S><I><H><Y><F><R><V><P><R><F><Y><W><K><D><R><L><L><K><M><K><M><A><G><L><N><A><I><Q><T><Y><V><P><W><N><F><H><E><P><Q><P><G><Q><Y><Q><F><S><G><E><H><D><V><E><Y...
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.<BOP>
O19015
A6TR38
EX7L_ALKMQ
Exodeoxyribonuclease VII large subunit
Alkaliphilus
<M><Q><I><K><A><L><S><V><S><E><I><N><H><Y><I><K><R><I><M><I><N><D><P><I><L><S><N><V><Y><I><K><G><E><I><S><N><Y><K><L><H><S><S><G><H><I><Y><F><T><L><K><D><E><K><S><R><V><S><S><V><M><F><K><T><N><T><E><Q><L><K><F><L><P><E><E><G><M><Q><V><L><C><R><G><Y><I><S><L><Y><E><R><G><G><L><Y><Q><F><Y><V><D><H><M><E><A><A><G><V><G><A...
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.<BOP>
A6TR38
P0CW58
RADA_METMI
DNA repair and recombination protein RadA
Methanococcus
<M><A><D><V><L><T><E><L><P><G><V><G><P><S><T><A><D><K><L><I><E><G><G><Y><L><D><F><M><K><I><A><T><A><T><I><G><E><L><T><D><I><E><G><I><S><E><K><A><A><A><K><M><I><M><A><A><R><D><L><C><D><L><G><F><K><S><G><V><E><L><L><K><Q><R><Q><S><V><W><R><L><S><T><G><S><T><E><L><G><T><V><L><A><G><G><I><E><S><Q><S><V><T><E><F><A><G><M><F...
Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.<BOP>
P0CW58
Q5LW06
RNPA_RUEPO
Protein C5
Ruegeria
<M><P><P><A><V><S><V><C><A><S><S><G><I><S><V><L><R><K><R><S><D><F><L><K><A><A><R><A><R><R><Q><G><A><G><S><M><M><V><Q><A><R><K><R><D><A><G><E><A><E><G><I><R><V><G><F><T><C><S><K><K><V><G><N><A><V><A><R><N><R><A><K><R><R><L><R><E><A><A><R><L><V><L><P><D><M><G><R><P><G><W><D><Y><V><L><I><G><R><P><S><D><T><A><S><R><P><F><D...
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the riboz...
Q5LW06
O70453
HMOX3_RAT
Putative heme oxygenase 3
Rattus
<M><S><S><E><V><E><T><A><E><A><V><D><E><S><E><K><N><S><M><A><S><E><K><E><N><H><S><K><I><A><D><F><S><D><L><L><K><E><G><T><K><E><A><D><D><R><A><E><N><T><Q><F><V><K><D><F><L><K><G><N><I><K><K><E><L><F><K><L><A><T><T><A><L><S><Y><S><A><P><E><E><E><M><D><S><L><T><K><D><M><E><Y><F><F><G><E><N><W><E><E><K><V><K><C><S><E><A><A...
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Heme oxygenase 3 could be implicated in some heme-dependent regulatory role in the cell.<BOP>
O70453
A1B036
RS17_PARDP
30S ribosomal protein S17
Paracoccus
<M><P><K><R><I><L><Q><G><K><V><V><S><D><K><N><E><Q><T><V><T><V><L><V><E><R><R><F><K><H><P><L><L><H><K><T><V><R><S><S><K><K><Y><R><A><H><D><A><D><N><Q><F><K><V><G><D><T><V><R><I><V><E><C><A><P><I><S><K><T><K><R><W><T><V><L><T><E><T><A><E><V><S><A>
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.<BOP>
A1B036
A6VQU4
MNTP_ACTSZ
Putative manganese efflux pump MntP
Actinobacillus
<M><S><Y><Y><T><L><W><V><I><A><F><G><L><S><M><D><A><F><A><V><S><V><G><K><G><L><T><L><A><D><F><C><W><K><F><T><L><K><I><A><L><C><F><G><L><F><Q><A><C><M><P><L><L><G><Y><Y><V><G><S><H><F><S><D><Y><I><S><E><F><D><H><W><I><A><F><A><L><L><C><V><I><G><I><N><M><I><K><M><S><V><T><N><E><N><S><D><D><D><P><S><D><F><S><L><R><H><L><T...
Probably functions as a manganese efflux pump.<BOP>
A6VQU4
Q13EA7
GLGA_RHOPS
Starch [bacterial glycogen] synthase
Rhodopseudomonas
<M><T><T><L><T><A><L><S><V><A><S><E><I><F><P><L><I><K><T><G><G><L><A><D><V><T><G><A><L><P><A><A><V><K><A><H><G><V><A><M><R><T><L><V><P><G><Y><P><A><V><L><G><G><I><E><D><P><Q><Q><V><H><S><F><T><E><F><F><G><G><S><A><R><L><L><A><A><R><C><D><E><L><E><L><L><V><L><D><A><P><H><L><Y><V><R><P><G><N><P><Y><V><G><P><D><A><K><D><W...
Synthesizes alpha-1,4-glucan chains using ADP-glucose.<BOP>
Q13EA7
Q7MYG7
RL18_PHOLL
50S ribosomal protein L18
Photorhabdus
<M><D><K><K><A><A><R><I><R><R><A><T><R><A><R><R><K><L><Q><E><L><G><A><T><R><L><V><V><H><R><T><P><R><H><I><Y><A><Q><V><I><A><P><N><G><S><E><T><L><V><A><A><S><T><T><E><K><A><I><N><E><Q><L><K><Y><T><G><N><K><E><A><A><A><A><V><G><K><A><I><A><E><R><A><L><E><K><G><I><K><D><V><S><F><D><R><S><G><F><Q><Y><H><G><R><V><Q><A><L><A...
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP>
Q7MYG7
Q72CI5
RS12_DESVH
30S ribosomal protein S12
Desulfovibrio
<M><P><T><I><N><Q><L><I><R><K><E><R><K><K><V><V><K><R><K><K><T><P><A><L><Q><A><C><P><Q><R><R><G><V><C><T><R><V><Y><T><T><T><P><K><K><P><N><S><A><L><R><K><V><A><R><V><R><L><T><N><G><L><E><V><T><A><Y><I><P><G><E><G><H><N><L><Q><E><H><S><V><V><M><I><R><G><G><R><V><K><D><L><P><G><V><R><Y><H><I><V><R><G><T><L><D><T><S><G><V...
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com...
Q72CI5
Q3V8A3
PDXA_METCA
4-(phosphohydroxy)-L-threonine dehydrogenase
Methylococcus
<M><P><P><R><L><L><L><T><S><G><E><P><A><G><I><G><P><D><L><C><V><L><L><S><R><R><P><F><P><C><G><I><T><V><L><G><D><P><D><L><L><E><S><R><A><R><L><L><G><V><P><I><E><L><R><R><V><V><S><G><D><V><V><P><P><H><E><P><G><V><L><H><V><L><P><T><R><R><Q><P><G><T><A><P><G><K><L><D><P><A><N><A><A><Y><V><L><E><T><I><A><D><G><A><R><A><C><L...
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).<BOP>
Q3V8A3
D4D4Z2
MEP1_TRIVH
Fungalysin MEP1
Trichophyton
<M><H><G><L><L><L><A><A><G><L><L><S><L><P><L><H><V><L><A><H><P><Q><P><S><T><S><T><S><L><A><G><R><A><G><A><V><D><L><N><E><F><R><I><A><H><R><S><S><Y><T><S><H><D><E><M><K><K><L><P><S><I><A><S><F><R><Q><G><T><Y><L><E><V><A><T><E><L><V><K><Q><T><I><P><N><M><E><F><R><L><V><D><D><H><Y><V><G><D><S><G><I><G><H><V><R><F><R><Q><T...
Secreted metalloproteinase probably acting as a virulence factor.<BOP>
D4D4Z2
Q1D290
RS18_MYXXD
30S ribosomal protein S18
Myxococcus
<M><S><N><G><T><D><S><K><T><A><S><A><P><P><A><R><S><G><G><G><F><G><G><G><G><S><R><G><G><D><R><G><D><R><G><D><R><G><G><D><R><G><D><R><G><G><G><L><G><G><D><D><D><K><R><G><G><G><R><G><F><G><R><K><K><V><C><R><F><C><A><E><K><N><A><S><V><D><F><K><D><Q><A><T><L><K><Y><F><V><T><E><R><G><K><I><I><P><R><R><I><S><G><N><C><A><K><H...
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.<BOP>
Q1D290
P04268
TPM1_CHICK
Tropomyosin-1
Gallus
<M><D><A><I><K><K><K><M><Q><M><L><K><L><D><K><E><N><A><L><D><R><A><E><Q><A><E><A><D><K><K><A><A><E><E><R><S><K><Q><L><E><D><E><L><V><A><L><Q><K><K><L><K><G><T><E><D><E><L><D><K><Y><S><E><S><L><K><D><A><Q><E><K><L><E><L><A><D><K><K><A><T><D><A><E><S><E><V><A><S><L><N><R><R><I><Q><L><V><E><E><E><L><D><R><A><Q><E><R><L><A...
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing c...
P04268
Q9Y343
SNX24_HUMAN
Sorting nexin-24
Homo
<M><E><V><Y><I><P><S><F><R><Y><E><E><S><D><L><E><R><G><Y><T><V><F><K><I><E><V><L><M><N><G><R><K><H><F><V><E><K><R><Y><S><E><F><H><A><L><H><K><K><L><K><K><C><I><K><T><P><E><I><P><S><K><H><V><R><N><W><V><P><K><V><L><E><Q><R><R><Q><G><L><E><T><Y><L><Q><A><V><I><L><E><N><E><E><L><P><K><L><F><L><D><F><L><N><V><R><H><L><P><S...
May be involved in several stages of intracellular trafficking.<BOP>
Q9Y343
P45751
HOFO_ECOLI
DNA utilization protein HofO
Escherichia
<M><N><M><F><F><D><W><W><F><A><T><S><P><R><L><R><Q><L><C><W><A><F><W><L><L><M><L><V><T><L><I><F><L><S><S><T><H><H><E><E><R><D><A><L><I><R><L><R><A><S><H><H><Q><Q><W><A><A><L><Y><R><L><V><D><T><A><P><F><S><E><E><K><T><L><P><F><S><P><L><D><F><Q><L><S><G><A><Q><L><V><S><W><H><P><S><A><Q><G><G><E><L><A><L><K><T><L><W><E><A...
Required for the use of extracellular DNA as a nutrient.<BOP>
P45751
Q7NC21
EFTS_MYCGA
Elongation factor Ts
Mycoplasma
<M><A><S><I><T><E><L><I><K><Q><L><R><A><S><T><Q><A><G><F><M><D><C><K><K><A><L><E><A><T><N><N><D><I><D><Q><A><I><K><W><L><R><E><N><G><I><A><K><A><A><K><K><V><D><N><V><A><S><E><G><V><I><K><L><K><L><A><D><Q><K><A><T><I><L><E><I><N><S><Q><T><D><F><V><T><K><N><D><Q><F><V><A><F><S><N><E><L><V><D><L><V><H><K><H><E><T><T><D><V...
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.<BOP>
Q7NC21
A1U5I2
FETP_MARN8
Probable Fe(2+)-trafficking protein
Marinobacter
<M><S><R><T><V><F><C><R><K><Y><Q><K><E><L><E><G><L><A><M><P><P><M><P><G><P><K><G><Q><D><I><Y><E><N><V><S><K><L><A><W><E><E><W><Q><N><Q><Q><T><M><L><I><N><E><K><H><L><N><L><M><D><V><N><N><R><K><Y><L><Q><A><Q><M><E><R><F><F><N><N><E><P><F><D><Q><A><E><G><Y><V><P><P><E><K>
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.<BOP>
A1U5I2
P20459
IF2A_YEAST
Eukaryotic translation initiation factor 2 subunit alpha
Saccharomyces
<M><S><T><S><H><C><R><F><Y><E><N><K><Y><P><E><I><D><D><I><V><M><V><N><V><Q><Q><I><A><E><M><G><A><Y><V><K><L><L><E><Y><D><N><I><E><G><M><I><L><L><S><E><L><S><R><R><R><I><R><S><I><Q><K><L><I><R><V><G><K><N><D><V><A><V><V><L><R><V><D><K><E><K><G><Y><I><D><L><S><K><R><R><V><S><S><E><D><I><I><K><C><E><E><K><Y><Q><K><S><K><T...
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolys...
P20459
A9B415
RL2_HERA2
50S ribosomal protein L2
Herpetosiphon
<M><G><I><K><R><Y><K><P><T><S><P><G><R><R><G><M><T><V><S><D><F><A><E><I><T><K><F><E><P><E><K><S><L><T><E><P><L><K><K><H><A><G><R><N><N><H><G><H><I><T><T><R><H><R><G><G><G><H><K><R><R><Y><R><L><I><D><F><K><R><K><K><F><D><I><P><A><K><V><A><G><I><E><Y><D><P><N><R><S><A><N><I><A><L><L><H><Y><T><D><G><E><K><R><Y><I><I><A><P...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
A9B415
Q8D2Z3
MRAY_WIGBR
UDP-MurNAc-pentapeptide phosphotransferase
Wigglesworthia
<M><L><V><W><L><C><E><K><L><V><Y><L><Y><S><G><F><N><V><F><S><Y><L><T><I><R><S><I><I><S><L><L><T><S><F><F><L><S><L><F><F><G><P><R><V><I><L><F><L><K><K><F><Q><I><K><Q><I><I><R><L><D><G><P><K><S><H><L><Y><K><C><N><T><P><T><M><G><G><V><M><I><L><V><S><V><I><F><S><V><L><S><W><S><H><L><S><N><S><Y><I><W><Y><V><L><Y><V><L><T><G...
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I...
Q8D2Z3
A0A0A2IJP3
CNSP_PENEN
Communesin biosynthesis cluster protein P
Penicillium
<M><S><T><T><T><V><I><T><P><G><T><I><T><R><E><K><N><E><N><G><A><P><L><Y><P><D><Y><M><P><F><Y><D><P><L><E><K><V><E><D><I><G><A><F><E><H><F><D><P><G><H><R><A><D><P><K><L><P><N><L><L><K><N><A><T><K><V><W><E><L><S><P><H><V><G><T><E><I><H><G><V><Q><L><S><Q><L><D><S><A><G><L><D><E><L><A><L><L><A><A><Q><R><G><A><L><V><F><R><D...
Alpha-ketoglutarate-dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of communesins, a prominent class of indole alkaloids with great potential as pharmaceuticals . Communesins are biosynthesized by the coupling of tryptamine and aurantioclavine, two building blocks derived from L-tryptoph...
A0A0A2IJP3
Q7VRE2
DXR_BLOFL
2-C-methyl-D-erythritol 4-phosphate synthase
Candidatus Blochmannia
<M><I><S><G><A><Q><Q><Y><R><D><K><F><A><V><R><A><L><V><A><H><N><D><V><A><V><M><I><E><Q><C><F><L><V><S><P><Q><Y><V><C><M><I><C><E><E><V><A><R><N><L><K><Y><K><L><V><L><M><D><K><N><N><I><Q><V><L><S><G><M><K><D><A><C><V><L><S><A><L><D><A><V><D><M><V><V><S><T><M><A><G><I><A><R><L><Q><P><I><F><S><A><I><R><V><G><K><K><I><L><L...
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
Q7VRE2
A8G3M2
PURA_PROM2
IMP--aspartate ligase
Prochlorococcus
<M><A><N><V><V><V><I><G><A><Q><W><G><D><E><G><K><G><K><I><T><D><L><L><S><R><S><A><D><V><V><V><R><Y><Q><G><G><V><N><A><G><H><T><I><V><V><D><D><K><V><L><K><L><H><L><I><P><S><G><I><L><Y><K><N><T><S><C><L><I><G><S><G><T><V><V><D><P><K><I><L><L><K><E><I><D><M><L><I><D><N><G><I><D><I><S><G><L><K><I><S><S><T><S><H><V><T><M><P...
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP>
A8G3M2
Q2S9R9
RISB_HAHCH
6,7-dimethyl-8-ribityllumazine synthase
Hahella
<M><T><V><K><V><V><E><G><D><F><L><Q><G><A><S><A><K><Y><A><I><V><V><G><R><F><N><S><F><V><V><E><S><L><L><E><G><A><L><D><A><L><R><R><H><G><V><A><E><S><Q><I><T><V><Y><R><A><P><G><A><F><E><I><P><L><L><A><Q><Q><V><A><V><R><T><K><P><D><A><V><I><A><L><G><A><V><I><R><G><G><T><P><H><F><E><Y><V><A><G><E><C><A><K><G><L><G><Q><V><S...
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<BOP>
Q2S9R9
P28056
CYB6_SYNP2
Cytochrome b6
unclassified Synechococcus
<M><F><T><K><E><V><T><D><S><K><L><Y><K><W><F><N><E><R><L><E><I><Q><A><I><S><D><D><I><S><S><K><Y><V><P><P><H><V><N><I><F><Y><C><L><G><G><I><T><L><T><C><F><I><I><Q><F><A><T><G><F><A><M><T><F><Y><Y><K><P><T><V><A><E><A><F><T><S><V><Q><Y><I><M><N><E><V><N><F><G><W><L><I><R><S><I><H><R><W><S><A><S><M><M><V><L><M><M><I><L><H...
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.<BOP>
P28056
A7FSG8
HEM3_CLOB1
Pre-uroporphyrinogen synthase
Clostridium
<M><N><F><V><I><A><T><R><R><S><K><L><A><Q><V><Q><T><E><I><I><I><D><L><L><N><K><K><H><D><I><E><C><E><K><L><L><I><E><T><V><G><D><K><I><L><E><V><S><L><D><K><I><G><G><K><G><L><F><V><K><D><I><E><V><A><M><L><E><Q><R><A><D><A><A><V><H><S><M><K><D><V><P><Y><E><M><P><K><G><F><E><I><I><A><I><P><E><R><E><D><V><R><D><A><F><I><S><L...
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.<BOP>
A7FSG8
Q3T1J8
RTF2_RAT
Replication termination factor 2 domain-containing protein 1
Rattus
<M><G><C><D><G><G><T><I><P><K><R><H><E><L><V><K><G><P><K><K><V><E><K><V><D><K><D><A><E><L><V><A><Q><W><N><Y><C><T><L><S><Q><E><V><L><R><R><P><I><V><A><C><E><L><G><R><L><Y><N><K><D><A><V><I><E><F><L><L><D><K><S><A><E><K><A><L><G><K><A><T><S><H><I><R><S><I><K><N><V><T><E><L><K><L><S><D><N><P><A><W><E><G><D><K><G><N><T><K...
Replication termination factor which is a component of the elongating replisome. Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signalin...
Q3T1J8
A4TP60
FOLD_YERPP
Methenyltetrahydrofolate cyclohydrolase
Yersinia
<M><S><A><K><I><I><D><G><K><T><I><A><Q><Q><V><R><N><E><V><A><A><V><V><Q><Q><R><L><A><A><G><K><R><A><P><G><L><A><V><V><L><V><G><E><N><P><A><S><Q><I><Y><V><A><S><K><R><K><A><C><E><E><V><G><F><V><S><R><S><Y><D><L><P><M><A><T><S><E><A><E><L><L><A><L><I><D><S><L><N><E><D><T><E><I><D><G><I><L><I><Q><L><P><L><P><N><G><I><D><N...
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP>
A4TP60
Q84J75
PG2B1_ARATH
Rab geranylgeranyl transferase beta subunit 1
Arabidopsis
<M><S><S><T><S><S><S><Q><M><V><Q><L><V><A><D><K><H><V><R><Y><I><L><M><A><E><K><K><K><E><S><F><E><S><V><V><M><D><H><L><R><M><N><G><A><Y><W><G><L><T><T><L><D><L><L><D><K><L><G><C><V><S><E><E><E><V><I><S><W><L><M><T><C><Q><H><E><S><G><G><F><A><G><N><T><G><H><D><P><H><I><L><Y><T><L><S><A><V><Q><I><L><A><L><F><D><K><I><N><I...
Required for male fertility and root tip growth.<BOP>
Q84J75
Q54BN0
TMEDB_DICDI
Transmembrane emp24 domain-containing protein B
Dictyostelium
<M><N><K><T><N><Q><L><I><N><I><C><I><L><V><T><L><F><L><I><G><S><S><S><A><L><T><L><Q><V><E><P><K><S><Q><E><C><F><Y><N><F><I><E><S><G><K><T><S><L><L><L><Y><Q><V><I><R><G><G><L><L><D><I><N><V><K><L><T><D><P><K><G><N><T><I><F><E><R><L><H><F><D><T><Q><M><K><G><K><Q><S><F><T><A><G><E><S><G><A><Y><K><V><C><F><N><N><E><M><S><R...
Could have a role in the budding of coatomer-coated and other species of coated vesicles.<BOP>
Q54BN0
Q5QY61
TRMB_IDILO
tRNA(m7G46)-methyltransferase
Idiomarina
<M><S><H><F><K><S><A><E><E><A><A><A><A><G><K><Y><V><R><T><V><R><S><F><V><K><R><E><G><R><L><T><K><G><Q><A><A><A><I><E><R><L><W><P><T><V><G><L><T><L><E><N><G><R><L><D><L><A><M><V><F><G><R><E><A><P><V><T><L><E><I><G><F><G><M><G><H><S><L><V><E><M><A><A><N><A><P><E><R><D><F><I><G><I><E><V><H><E><P><G><V><G><A><C><L><M><A><A...
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP>
Q5QY61
Q8BUZ1
ABRA_MOUSE
Striated muscle activator of Rho-dependent signaling
Mus
<M><A><P><G><E><R><E><R><E><A><G><P><A><K><S><A><L><R><K><V><R><T><A><T><L><V><I><N><L><A><R><G><W><Q><Q><W><A><N><E><N><S><T><K><Q><A><Q><E><P><A><G><W><L><P><G><A><T><H><D><L><P><N><A><P><K><E><A><G><P><Y><Q><H><A><P><K><T><L><S><P><K><P><D><R><D><G><E><G><Q><H><S><E><E><A><T><E><V><S><H><I><K><R><K><E><V><T><R><T><V...
Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.<BOP>
Q8BUZ1
P59355
SCX2_LEIHE
Lqh II
Leiurus
<I><K><D><G><Y><I><V><D><D><V><N><C><T><Y><F><C><G><R><N><A><Y><C><N><E><E><C><T><K><L><K><G><E><S><G><Y><C><Q><W><A><S><P><Y><G><N><A><C><Y><C><Y><K><L><P><D><H><V><R><T><K><G><P><G><R><C><R>
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. The dissociation is voltage-dependent. Is active on mammals and competes for alpha-toxins binding on both mammalian and cockroach sodium channels.<BO...
P59355
P0A4I9
SIGA_STRPN
RNA polymerase sigma factor SigA
Streptococcus
<M><A><T><K><Q><K><E><V><T><T><F><D><V><Q><V><A><E><F><I><R><N><H><K><Q><K><G><T><A><T><D><D><E><I><N><A><S><L><V><I><P><F><T><L><D><A><D><G><I><E><D><L><L><Q><R><I><Q><D><A><G><I><S><I><T><D><N><E><G><N><P><S><A><R><V><L><S><N><E><E><E><P><E><L><S><D><E><D><L><I><G><S><T><S><A><K><V><N><D><P><V><R><M><Y><L><K><E><I><G...
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.<BOP>
P0A4I9
Q5PJR1
DCTA_SALPA
C4-dicarboxylate transport protein
Salmonella
<M><K><T><S><L><F><K><S><L><Y><F><Q><V><L><T><A><I><A><I><G><I><L><L><G><H><Y><Y><P><E><L><G><A><Q><M><K><P><L><G><D><A><F><V><K><L><I><K><M><I><I><A><P><V><I><F><C><T><V><V><T><G><I><A><G><M><E><S><M><K><A><V><G><R><T><G><A><V><A><L><L><Y><F><E><I><V><S><T><I><A><L><I><I><G><L><I><I><V><N><V><V><Q><P><G><A><G><M><N><V...
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.<BOP>
Q5PJR1
P09758
TACD2_HUMAN
Pancreatic carcinoma marker protein GA733-1
Homo
<M><A><R><G><P><G><L><A><P><P><P><L><R><L><P><L><L><L><L><V><L><A><A><V><T><G><H><T><A><A><Q><D><N><C><T><C><P><T><N><K><M><T><V><C><S><P><D><G><P><G><G><R><C><Q><C><R><A><L><G><S><G><M><A><V><D><C><S><T><L><T><S><K><C><L><L><L><K><A><R><M><S><A><P><K><N><A><R><T><L><V><R><P><S><E><H><A><L><V><D><N><D><G><L><Y><D><P><D...
May function as a growth factor receptor.<BOP>
P09758
B7GFA1
PYRDB_ANOFW
Orotate reductase (NADH)
Anoxybacillus
<M><N><R><L><A><V><E><L><P><G><L><S><L><K><N><P><I><M><P><A><S><G><C><F><G><F><G><R><E><Y><A><K><F><Y><D><L><S><V><L><G><A><M><M><I><K><A><T><T><L><E><A><R><F><G><N><P><T><P><R><V><A><E><T><P><S><G><M><L><N><A><I><G><L><Q><N><P><G><V><D><Y><V><L><A><E><E><L><P><W><L><A><Q><Y><D><V><P><I><I><A><N><V><A><G><S><T><V><E><E...
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.<BOP>
B7GFA1
Q1QR53
YCIB_NITHX
Inner membrane-spanning protein YciB
Nitrobacter
<M><D><K><K><Q><P><H><P><L><F><K><L><A><T><E><L><G><P><L><L><V><F><F><A><A><N><A><K><F><N><L><F><V><A><T><A><A><F><M><V><A><I><V><A><A><M><I><A><S><Y><V><V><T><R><H><I><P><L><M><A><L><V><T><G><I><V><V><I><V><F><G><T><L><T><L><V><L><H><D><E><T><F><I><K><V><K><P><T><I><I><Y><S><L><F><A><G><V><L><G><G><G><L><L><F><G><R><S...
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP>
Q1QR53
P83674
LANA_RUMGN
RumA protein 1/2/3
Mediterraneibacter
<M><R><N><D><V><L><T><L><T><N><P><M><E><E><K><E><L><E><Q><I><L><G><G><G><N><G><V><L><K><T><I><S><H><E><C><N><M><N><T><W><Q><F><L><F><T><C><C>
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. Ruminococcin A is a broad spectrum bacteriocin exhibitin...
P83674
Q0VSL7
EFTU_ALCBS
Elongation factor Tu
Alcanivorax
<M><A><K><E><K><F><E><R><N><K><P><H><V><N><V><G><T><I><G><H><V><D><H><G><K><T><T><L><T><A><A><L><T><R><V><C><A><E><V><W><G><G><N><A><V><A><F><D><G><I><D><N><A><P><E><E><R><E><R><G><I><T><I><A><T><S><H><V><E><Y><D><S><P><T><R><H><Y><A><H><V><D><C><P><G><H><A><D><Y><V><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V><C><S...
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP>
Q0VSL7
P0ADC7
LPTG_ECOL6
Lipopolysaccharide export system permease protein LptG
Escherichia
<M><Q><P><F><G><V><L><D><R><Y><I><G><K><T><I><F><T><T><I><M><M><T><L><F><M><L><V><S><L><S><G><I><I><K><F><V><D><Q><L><K><K><A><G><Q><G><S><Y><D><A><L><G><A><G><M><Y><T><L><L><S><V><P><K><D><V><Q><I><F><F><P><M><A><A><L><L><G><A><L><L><G><L><G><M><L><A><Q><R><S><E><L><V><V><M><Q><A><S><G><F><T><R><M><Q><V><A><L><S><V><M...
Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.<BOP>
P0ADC7
Q73V46
SSRP_MYCPA
Small protein B
Mycobacterium avium complex (MAC)
<M><A><K><G><S><G><R><A><K><A><A><G><G><K><G><G><S><K><Q><I><I><A><T><N><R><K><A><R><H><N><Y><S><I><I><E><T><Y><E><A><G><V><A><L><Q><G><T><E><V><K><S><L><R><E><G><Q><A><S><L><A><D><A><F><A><T><I><D><D><G><E><V><W><L><R><N><L><Y><I><P><E><Y><Q><H><G><S><W><T><N><H><D><P><R><R><N><R><K><L><L><L><H><R><Q><Q><I><D><R><L><V...
Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb...
Q73V46
A0L052
PURT_SHESA
Phosphoribosylglycinamide formyltransferase 2
Shewanella
<M><I><G><T><P><Y><T><E><G><A><R><R><A><M><L><L><G><C><G><E><L><G><K><E><V><A><I><E><L><Q><R><L><G><V><E><V><I><G><V><D><R><Y><P><N><A><P><A><M><Q><I><A><H><R><S><H><V><I><N><M><L><D><A><K><A><L><R><A><I><I><E><L><E><K><P><H><L><V><I><P><E><I><E><A><I><A><T><Q><T><L><V><E><M><E><T><E><G><L><N><V><V><P><T><A><R><A><T><Q...
Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.<BOP>
A0L052
A4Q998
PNPH_ANOGA
Inosine-guanosine phosphorylase
Anopheles
<M><S><K><F><S><Y><L><Q><N><G><K><A><S><T><N><G><V><P><H><A><N><G><H><H><Q><Q><H><Q><N><G><H><S><N><G><V><A><R><N><G><G><T><A><T><D><T><L><P><V><A><Y><Q><Q><K><A><A><T><S><G><P><F><H><M><P><R><T><E><H><V><G><Y><T><Y><D><T><L><Q><E><I><A><T><Y><L><L><E><R><T><E><L><R><P><K><V><G><I><I><C><G><S><G><L><G><T><L><A><E><Q><L...
As part of the purine salvage pathway, catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate . Preferentially acts on 2'-deoxyinosine and inosine, and to a lesser extent on 2'-deoxygu...
A4Q998
Q5HH12
PUR3_STAAC
GAR transformylase
Staphylococcus
<M><V><K><I><A><I><F><A><S><G><S><G><S><N><F><E><N><I><V><E><H><V><E><S><G><K><L><E><N><I><E><V><T><A><L><Y><T><D><H><Q><N><A><F><C><I><D><R><A><K><K><H><D><I><P><V><Y><I><N><E><P><K><Q><F><D><S><K><A><A><Y><E><Q><H><L><V><T><L><L><N><E><D><K><V><E><W><I><I><L><A><G><Y><M><R><L><I><G><P><D><L><L><A><S><F><E><G><K><I><L...
Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.<BOP>
Q5HH12
D3YTS9
PPAT_MOUSE
Acid phosphatase 4
Mus
<M><A><E><P><G><S><Q><G><H><T><V><G><P><L><L><L><L><L><L><L><L><L><P><R><A><L><P><E><G><P><L><L><F><V><A><L><V><F><R><H><G><D><R><A><P><L><A><S><Y><P><T><D><P><H><K><E><A><A><S><T><L><W><P><R><G><L><G><Q><L><T><K><E><G><I><R><Q><Q><L><E><L><G><R><F><L><R><R><R><Y><K><A><F><L><S><P><E><Y><K><R><E><E><V><Y><I><R><S><T><D...
May dephosphorylate receptor tyrosine-protein kinase ERBB4 and inhibits its ligand-induced proteolytic cleavage. May play a role in odontogenesis.<BOP>
D3YTS9
Q58DW5
RL5_BOVIN
60S ribosomal protein L5
Bos
<M><G><F><V><K><V><V><K><N><K><A><Y><F><K><R><Y><Q><V><K><F><R><R><R><R><E><G><K><T><D><Y><Y><A><R><K><R><L><V><I><Q><D><K><N><K><Y><N><T><P><K><Y><R><M><I><V><R><V><T><N><R><D><I><I><C><Q><I><A><Y><A><R><I><E><G><D><M><I><V><C><A><A><Y><A><H><E><L><P><K><Y><G><V><K><V><G><L><T><N><Y><A><A><A><Y><C><T><G><L><L><L><A><R...
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosom...
Q58DW5
Q6AP62
RS17_DESPS
30S ribosomal protein S17
Desulfotalea
<M><S><E><N><N><T><S><R><K><T><R><T><G><S><V><V><S><D><R><M><E><K><S><V><V><V><R><V><E><R><K><V><R><H><K><L><Y><G><K><F><M><K><T><S><V><K><Y><L><A><D><D><P><E><N><Q><C><N><I><G><D><V><V><L><I><E><E><C><R><P><L><S><K><R><K><R><W><R><V><K><T><I><L><E><Q><A><V>
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.<BOP>
Q6AP62
Q00497
SK_SOLLC
Shikimate kinase, chloroplastic
Solanum subgen. Lycopersicon
<M><E><A><R><V><S><Q><S><L><Q><L><S><S><W><I><N><S><D><K><V><V><R><K><P><S><G><L><L><R><F><S><E><K><W><N><E><K><P><R><H><R><V><V><V><S><C><H><L><Q><P><R><K><A><A><H><S><D><R><R><V><Q><L><K><V><S><C><S><P><Q><N><V><Q><A><S><V><L><E><S><G><C><F><S><A><S><I><D><E><I><E><T><L><K><N><K><A><E><E><V><E><E><Y><L><D><G><R><C><V...
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.<BOP>
Q00497
O94643
CENPU_SCHPO
Sim4 complex subunit mis17
Schizosaccharomyces
<M><E><N><N><S><H><N><V><D><E><R><R><A><A><R><M><R><G><A><E><R><Y><K><I><Q><N><V><E><F><S><L><D><Q><N><L><L><A><N><L><E><S><S><T><S><S><S><T><R><S><S><P><A><S><N><Q><Q><N><L><E><I><V><S><Q><S><E><A><Y><H><K><I><S><D><L><D><D><S><T><S><I><F><S><I><S><D><Q><E><N><I><L><E><R><R><I><S><E><E><V><V><R><E><N><S><V><S><S><I><E...
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore COMA complex, which connects centromere-associated pro...
O94643
Q0C5U1
GLMM_HYPNA
Phosphoglucosamine mutase
Hyphomonas
<M><A><R><Q><Y><F><G><T><D><G><I><R><G><R><V><N><T><S><P><M><T><A><E><T><A><L><R><L><S><I><A><A><A><R><T><F><A><P><E><G><G><R><E><V><V><I><G><R><D><T><R><R><S><G><D><M><I><E><A><A><L><V><A><G><F><T><S><M><G><I><T><P><V><L><L><G><V><V><P><T><P><A><V><A><L><M><A><R><E><T><G><A><A><L><G><V><M><V><S><A><S><H><N><K><F><E><D...
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.<BOP>
Q0C5U1
Q923D2
BLVRB_MOUSE
NADPH-flavin reductase
Mus
<M><T><V><K><K><I><A><I><F><G><A><T><G><R><T><G><L><T><T><L><A><Q><A><V><Q><A><G><Y><E><V><T><V><L><V><R><D><S><S><R><L><P><S><E><G><P><Q><P><A><H><V><V><V><G><D><V><R><Q><A><A><D><V><D><K><T><V><A><G><Q><E><A><V><I><V><L><L><G><T><G><N><D><L><S><P><T><T><V><M><S><E><G><T><R><N><I><V><T><A><M><K><A><H><G><V><D><K><V><V...
Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) i...
Q923D2
Q8W4Q3
PIRL3_ARATH
Plant intracellular Ras-group-related LRR protein 3
Arabidopsis
<M><D><H><D><L><E><I><F><P><L><L><S><Y><V><L><H><H><S><D><P><A><S><H><A><P><P><S><L><A><I><Q><Q><S><L><A><N><R><Y><P><L><L><T><N><P><Y><V><I><S><S><L><I><E><S><I><P><S><T><I><T><Q><T><L><F><V><F><G><S><L><G><P><R><P><D><P><L><A><V><S><S><A><R><S><K><I><R><E><I><K><E><N><D><S><L><S><P><E><D><A><A><K><E><E><Q><V><Y><A><A...
Leucine-rich repeat protein that likely mediates protein interactions, possibly in the context of signal transduction.<BOP>
Q8W4Q3
Q1DFX4
KDPC_MYXXD
Potassium-translocating ATPase C chain
Myxococcus
<M><F><S><T><F><L><T><A><L><R><T><C><V><V><T><M><V><L><T><G><L><L><Y><P><L><A><V><T><G><L><A><Q><L><L><F><P><G><E><A><N><G><S><W><V><K><D><G><R><G><R><V><V><G><S><A><L><I><G><Q><G><F><T><R><A><G><Y><F><H><P><R><P><S><A><A><G><A><G><Y><D><G><A><A><S><S><G><S><N><L><G><P><T><S><L><K><L><K><E><R><A><A><A><E><L><E><R><L><R...
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation...
Q1DFX4
B2UGM5
1A1D_RALPJ
1-aminocyclopropane-1-carboxylate deaminase
Ralstonia
<M><N><L><Q><R><F><P><R><Y><P><L><T><F><G><P><T><P><I><Q><P><L><K><R><L><S><A><H><L><G><G><K><V><E><L><F><A><K><R><E><D><C><N><S><G><L><A><F><G><G><N><K><T><R><K><L><E><Y><L><I><P><E><A><L><E><G><G><Y><D><T><L><V><S><I><G><G><I><Q><S><N><Q><T><R><Q><V><A><A><V><A><A><H><L><G><L><K><C><V><L><V><Q><E><N><W><V><N><Y><S><D...
Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source.<BOP>
B2UGM5
Q4UWX9
MURD2_XANC8
UDP-N-acetylmuramoyl-L-alanyl-L-glutamate synthetase
Xanthomonas
<M><R><I><S><Q><L><E><G><K><A><V><A><L><W><G><W><A><R><E><G><R><A><A><Y><R><A><L><R><Q><Q><L><P><A><Q><P><L><T><V><F><C><N><A><E><E><A><R><D><V><A><A><L><A><D><P><A><L><Q><V><Q><T><E><A><S><A><Q><A><L><A><A><F><E><V><V><I><K><S><P><G><I><S><P><Y><R><E><E><A><R><A><A><A><A><Q><G><A><R><F><I><G><G><T><A><L><W><F><A><E><H...
Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.<BOP>
Q4UWX9
P56297
ATPH_CHLVU
Lipid-binding protein
Chlorella
<M><N><P><I><V><A><A><A><S><V><I><A><A><G><L><A><V><G><L><A><A><I><G><P><G><M><G><Q><G><T><A><A><G><Y><A><V><E><G><I><A><R><Q><P><E><A><E><G><K><I><R><G><A><L><L><L><S><F><A><F><M><E><S><L><T><I><Y><G><L><V><V><A><L><A><L><L><F><A><N><P><F><A><G>
Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.<BOP>
P56297
Q6PFQ0
KS6A6_DANRE
S6K-alpha 6-like
Danio
<M><I><S><F><G><P><A><Q><E><S><S><L><K><M><E><V><Q><S><V><S><S><E><V><N><G><H><Q><I><M><D><E><P><M><E><E><E><S><Y><T><H><C><D><E><G><A><Y><K><E><I><P><I><T><H><H><V><K><E><G><C><E><K><A><D><P><S><Q><F><E><L><L><K><V><L><G><Q><G><S><F><G><K><V><F><L><V><R><K><L><M><G><P><D><A><G><Q><L><Y><A><M><K><V><L><K><K><A><S><L><K...
Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.<BOP>
Q6PFQ0
O13498
MDM10_PODAN
Mitochondrial inheritance component MDM10
Podospora anserina
<M><R><E><F><M><Q><Y><V><R><N><A><F><Y><G><A><T><G><W><S><E><D><N><S><Y><K><D><L><N><V><T><A><R><E><L><I><D><F><P><L><P><R><G><I><R><L><S><L><S><S><L><A><T><P><H><F><A><T><S><Y><Q><L><C><N><V><G><V><V><D><G><S><I><S><Y><L><H><S><S><V><P><L><A><A><V><P><A><Q><S><N><K><I><P><L><G><A><L><M><R><S><Y><R><G><L><H><Q><L><G><S...
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of th...
O13498
Q978F3
PGMI_THEVO
Phosphomannose isomerase
Thermoplasma
<M><Q><F><S><E><E><L><L><T><L><K><D><Q><V><R><F><D><K><S><F><K><V><G><K><Y><D><K><I><V><I><A><G><M><G><G><S><G><I><A><G><R><I><F><S><E><I><Y><D><E><K><P><V><F><L><V><D><D><Y><D><I><P><S><F><V><D><D><K><T><E><F><I><A><I><S><Y><S><G><N><T><E><E><T><I><S><A><S><E><E><A><A><K><K><H><A><N><V><H><A><I><T><S><G><G><S><L><S><K...
Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency.<BOP>
Q978F3
Q4UMT0
RS10_RICFE
30S ribosomal protein S10
spotted fever group
<M><K><N><K><I><K><I><R><L><K><S><F><D><H><R><S><L><D><Q><A><T><K><E><I><V><S><A><V><K><R><T><F><A><N><I><N><G><P><I><P><L><P><R><K><I><E><R><F><T><V><N><R><S><P><H><V><H><K><K><S><R><E><Q><F><E><I><R><K><H><K><R><L><L><V><I><D><D><P><N><P><A><V><V><D><A><L><S><K><V><D><L><A><A><G><V><D><V><V><I><E><L><E><S><G><E>
Involved in the binding of tRNA to the ribosomes.<BOP>
Q4UMT0