accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
Q8BVN7
S2541_MOUSE
Solute carrier family 25 member 41
Mus
<M><G><V><H><L><E><V><L><D><T><G><E><Q><L><M><V><P><V><D><V><L><E><E><E><N><K><G><T><L><W><K><F><L><L><S><G><A><M><A><G><A><V><S><R><T><G><T><A><P><L><D><R><A><R><V><Y><M><Q><V><Y><S><S><K><S><N><F><R><N><L><L><S><G><L><R><S><L><V><Q><E><G><G><V><R><S><L><W><R><G><N><G><I><N><V><L><K><I><A><P><E><Y><A><I><K><F><S><V><C...
Calcium-independent ATP-Mg/Pi exchanger that catalyzes the electroneutral exchange of Mg-ATP or free ADP against an hydrogenphosphate and participates in the net transport of adenine nucleotides across the mitochondria inner membrane.<BOP>
Q8BVN7
Q5HUW9
TRUA_CAMJR
tRNA-uridine isomerase I
Campylobacter
<M><K><I><K><I><I><F><S><Y><D><G><T><A><F><L><G><S><A><T><Q><P><H><K><K><G><V><Q><D><A><L><S><G><A><L><S><H><L><G><I><F><S><P><L><L><M><A><S><R><T><D><K><G><V><H><A><S><Y><A><V><A><S><V><E><C><G><D><Y><F><T><N><L><E><Y><L><Q><K><Q><L><N><K><F><S><H><P><F><I><H><I><K><K><I><E><K><V><K><D><D><F><E><V><R><F><D><V><K><S><R...
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP>
Q5HUW9
Q9KDD7
GREA_HALH5
Transcript cleavage factor GreA
Halalkalibacterium (ex Joshi et al. 2022)
<M><A><E><E><K><K><H><Y><M><T><L><E><G><K><K><K><L><E><E><E><L><E><Y><L><K><T><E><R><R><K><E><V><V><E><R><I><K><I><A><R><S><F><G><D><L><S><E><N><S><E><Y><D><S><A><K><E><E><Q><A><F><V><E><G><R><I><S><Q><I><E><K><M><I><R><N><A><E><I><I><E><E><S><E><G><D><A><N><V><V><S><L><G><K><T><V><K><F><V><E><I><P><D><G><E><E><E><E><Y...
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factor...
Q9KDD7
Q1LI69
ENGB_CUPMC
Probable GTP-binding protein EngB
Cupriavidus
<M><S><L><L><H><Q><A><R><F><F><T><T><V><N><H><L><R><D><L><P><A><T><A><V><P><E><V><A><F><A><G><R><S><N><A><G><K><S><T><A><I><N><I><L><C><N><Q><K><R><L><A><F><S><S><R><T><P><G><R><T><Q><H><I><N><F><F><T><V><A><P><V><K><A><P><D><P><V><G><F><L><V><D><L><P><G><Y><G><Y><A><E><V><S><G><S><A><K><F><H><W><Q><G><L><L><S><D><Y><V...
Necessary for normal cell division and for the maintenance of normal septation.<BOP>
Q1LI69
Q07MP8
CTAA_RHOP5
Cytochrome aa3-controlling protein
Rhodopseudomonas
<M><P><G><S><A><A><A><R><P><L><R><A><V><K><I><W><L><G><A><I><A><A><L><I><A><A><M><V><L><V><G><G><A><T><R><L><T><E><S><G><L><S><I><V><E><W><K><P><I><T><G><T><L><P><P><L><T><D><A><Q><W><A><Q><A><F><E><G><Y><K><T><I><P><Q><Y><R><E><L><N><A><G><M><S><L><S><E><F><K><T><I><F><W><W><E><W><S><H><R><L><L><G><R><V><I><G><L><A><Y...
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.<BOP>
Q07MP8
P20045
REPB_LACPN
Replication protein RepB
Lactiplantibacillus
<M><K><S><E><S><K><I><D><W><T><V><P><R><P><N><K><N><P><K><T><K><Q><P><Y><K><R><G><R><N><W><G><I><V><V><Y><P><E><S><L><P><E><N><W><K><D><I><I><R><Q><E><P><I><A><V><S><P><L><H><D><K><D><V><N><P><D><G><E><K><K><K><S><H><Y><H><L><V><L><N><Y><K><G><N><K><S><F><E><Q><I><D><E><I><A><R><S><L><R><A><P><A><P><Q><R><I><S><S><L><T...
Is essential for plasmid replication. Nicks the positive strand at the plus origin of replication.<BOP>
P20045
Q3AGY2
TRPB_SYNSC
Tryptophan synthase beta chain
unclassified Synechococcus
<M><T><S><T><L><P><N><A><S><T><P><D><P><S><S><L><Q><P><A><V><R><P><G><A><H><G><R><F><G><R><F><G><G><Q><Y><V><P><E><T><L><M><P><A><L><A><E><L><E><Q><A><A><A><Q><A><W><N><D><P><A><F><T><D><E><L><N><R><L><L><K><N><Y><V><G><R><A><T><P><L><Y><E><A><E><R><L><T><A><H><Y><R><R><A><D><G><G><P><R><I><W><L><K><R><E><D><L><N><H><T...
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP>
Q3AGY2
Q0W8E0
PYRK_METAR
Dihydroorotate oxidase B, electron transfer subunit
Methanocella
<M><R><P><I><S><A><T><I><K><E><I><I><D><E><T><P><T><I><K><T><F><R><L><D><V><D><D><W><L><H><G><K><P><G><Q><Y><V><M><V><W><I><R><G><V><D><E><V><P><M><T><L><S><Y><D><N><A><I><T><V><Q><K><V><G><E><A><T><E><A><L><F><K><L><K><A><G><D><S><V><G><I><R><G><P><Y><G><N><G><W><E><I><V><G><D><D><I><L><L><I><S><G><G><V><G><S><A><P><L...
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).<BOP>
Q0W8E0
Q7U9J7
GLYA_PARMW
Serine hydroxymethyltransferase
Parasynechococcus marenigrum
<M><S><D><S><T><A><S><S><I><N><K><G><L><A><A><A><D><P><A><I><A><A><L><I><E><K><E><Q><Q><R><Q><E><T><H><L><E><L><I><A><S><E><N><F><A><S><R><A><V><M><D><A><Q><G><S><V><L><T><N><K><Y><A><E><G><L><P><S><K><R><Y><Y><G><G><C><E><H><V><D><A><I><E><E><L><A><I><E><R><A><K><E><L><F><G><A><A><W><A><N><V><Q><P><H><S><G><A><Q><A><N...
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a...
Q7U9J7
Q03VC2
CH10_LEUMM
Chaperonin-10
Leuconostoc
<M><L><K><P><L><G><D><R><V><I><I><E><V><T><E><A><A><E><E><T><V><G><G><I><V><L><A><S><N><A><K><D><K><P><V><T><G><K><V><V><A><A><G><T><G><Y><V><L><N><D><G><T><V><R><D><L><T><V><K><V><G><D><E><V><L><F><D><K><Y><A><G><Q><E><V><S><F><E><G><Q><D><Y><L><A><L><H><E><K><D><I><V><A><V><V><E>
Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of ...
Q03VC2
A5F2Q7
MOAC_VIBC3
Molybdenum cofactor biosynthesis protein C
Vibrio
<M><M><S><Q><L><T><H><I><N><A><S><G><E><A><N><M><V><D><V><S><N><K><A><D><T><V><R><E><A><R><A><E><A><Y><V><R><M><A><P><E><T><L><Q><L><I><L><S><G><Q><H><H><K><G><D><V><F><A><T><A><R><I><A><G><I><Q><A><A><K><R><T><W><E><L><I><P><L><C><H><P><L><L><L><S><K><V><E><V><Q><L><E><A><L><P><E><Q><S><S><V><R><I><E><S><L><C><K><L><S...
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).<BOP>
A5F2Q7
A1AI75
FDHD_ECOK1
Sulfur carrier protein FdhD
Escherichia
<M><K><K><T><Q><Q><K><E><I><E><N><V><T><N><I><T><G><V><R><Q><I><E><L><W><R><R><D><D><L><Q><H><P><R><L><D><E><V><A><E><E><V><P><V><A><L><V><Y><N><G><I><S><H><V><V><M><M><A><S><P><K><D><L><E><Y><F><A><L><G><F><S><L><S><E><G><I><I><E><S><P><R><D><I><F><G><M><D><V><V><P><S><C><N><G><L><E><V><Q><I><E><L><S><S><R><R><F><M><G...
Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.<BOP>
A1AI75
A4F9Z0
MSHB2_SACEN
N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 2
Saccharopolyspora
<M><L><V><H><A><H><P><D><D><E><S><T><G><T><G><A><T><M><A><R><Y><A><N><E><G><A><T><V><S><L><V><T><C><T><S><G><E><L><G><E><V><V><A><D><D><L><A><H><L><R><G><N><P><D><A><L><G><E><H><R><R><G><E><I><A><E><A><L><R><E><L><G><D><I><R><H><H><W><L><G><G><P><G><R><F><R><D><S><G><M><A><G><E><D><T><N><D><A><A><E><C><F><A><K><A><D><R...
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.<BOP>
A4F9Z0
P04002
ANPA_PSEAM
HPLC6
Pseudopleuronectes
<M><A><L><S><L><F><T><V><G><Q><L><I><F><L><F><W><T><M><R><I><T><E><A><S><P><D><P><A><A><K><A><A><P><A><A><A><A><A><P><A><A><A><A><P><D><T><A><S><D><A><A><A><A><A><A><L><T><A><A><N><A><K><A><A><A><E><L><T><A><A><N><A><A><A><A><A><A><A><T><A><R><G>
Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth.<BOP>
P04002
Q9D3B1
HACD2_MOUSE
Protein-tyrosine phosphatase-like member B
Mus
<M><A><A><A><A><A><T><A><A><T><K><G><N><G><G><G><S><G><R><V><G><A><G><D><S><S><G><A><R><K><K><K><G><P><G><P><V><A><T><A><Y><L><V><I><Y><N><V><V><M><T><A><G><W><L><V><I><A><V><G><L><V><R><A><Y><L><A><K><G><S><Y><H><S><L><Y><Y><S><I><E><R><P><L><K><F><F><Q><T><G><A><L><L><E><I><L><H><C><A><I><G><I><V><P><S><S><V><V><L><T...
Catalyzes the third of the very long-chain fatty acids (VLCFA) elongation four-step cycle (condensation, reduction, dehydration, and reduction). This endoplasmic reticulum-elongation process is characterized by the addition of two carbons to the lipid chain through each cycle. This enzyme catalyzes the dehydration of t...
Q9D3B1
Q3J6M9
ATPA_NITOC
F-ATPase subunit alpha
Nitrosococcus
<M><Q><L><Q><L><N><A><A><E><I><S><E><L><I><R><K><R><I><E><G><F><E><A><D><T><E><A><R><T><E><G><T><V><V><S><L><T><D><G><I><V><R><I><H><G><L><A><D><V><M><F><G><E><M><I><E><F><P><G><N><T><Y><G><L><A><M><N><L><E><R><D><S><V><G><A><V><I><L><G><P><Y><Q><H><I><S><E><G><D><R><A><K><C><T><G><R><I><L><E><V><P><V><G><E><A><L><L><G...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
Q3J6M9
Q1QSI0
RPOZ_CHRSD
Transcriptase subunit omega
Chromohalobacter
<M><A><R><V><T><V><E><D><C><L><D><N><V><D><N><R><F><Q><L><V><M><V><A><T><Q><R><S><R><Q><L><A><R><G><S><R><D><A><Q><L><P><W><E><N><D><K><P><T><V><M><A><L><R><E><I><A><A><G><L><V><D><R><S><I><L><N><E><A><V><E><P><P><A><A><K><P><R><P><E><R><E><F><N><D>
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP>
Q1QSI0
A0L2T2
ATPF_SHESA
F-type ATPase subunit b
Shewanella
<M><N><F><N><A><T><L><I><G><Q><T><V><A><F><I><I><F><V><W><F><C><M><K><F><V><W><P><P><L><M><N><A><I><E><A><R><Q><K><R><I><A><D><G><L><A><D><A><D><R><A><V><K><D><L><E><L><A><Q><A><K><A><T><D><Q><L><K><E><A><K><A><T><A><N><E><I><I><E><Q><A><N><K><R><K><A><Q><I><V><E><E><A><K><A><E><A><D><A><E><R><A><K><I><I><A><Q><G><K><A...
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).<BOP>
A0L2T2
A4X3B7
ENO_SALTO
2-phosphoglycerate dehydratase
Salinispora
<M><A><T><I><E><G><I><V><A><R><E><I><L><D><S><R><G><N><P><T><V><E><V><E><V><G><L><D><D><G><T><I><A><R><A><A><V><P><S><G><A><S><T><G><A><F><E><A><V><E><L><R><D><G><E><K><D><R><Y><L><G><K><G><V><T><Q><A><V><S><N><I><E><D><K><I><V><D><E><L><I><G><Y><E><A><S><E><Q><R><L><I><D><Q><K><M><L><D><L><D><G><T><D><N><K><S><Q><L><G...
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP>
A4X3B7
Q830V1
MGTE_ENTFA
Magnesium transporter MgtE
Enterococcus
<M><N><E><G><Q><E><M><E><E><Q><F><A><L><L><L><E><T><L><K><N><Q><Q><M><N><E><F><R><E><L><F><L><A><L><H><I><Y><E><Q><G><Q><F><Y><Q><S><L><D><E><K><D><R><Q><H><L><Y><N><Y><L><S><P><K><E><L><A><D><M><F><D><V><I><E><E><D><N><E><N><M><K><D><Y><L><A><E><M><R><P><S><Y><A><A><D><M><L><A><E><M><Y><T><D><N><A><V><D><L><L><N><M><L...
Acts as a magnesium transporter.<BOP>
Q830V1
Q3IHJ4
EX7L_PSET1
Exodeoxyribonuclease VII large subunit
Pseudoalteromonas
<M><F><S><K><P><L><Q><T><I><Y><T><V><S><R><L><N><R><E><I><R><A><L><L><E><Q><G><F><A><S><L><V><L><T><G><E><I><S><N><F><I><T><P><A><S><G><H><W><Y><F><S><L><K><D><D><K><A><Q><I><K><A><A><M><W><R><G><N><N><R><N><Q><S><Y><R><P><I><N><G><A><Q><V><T><V><K><A><R><V><S><L><Y><E><P><R><G><D><Y><Q><L><I><V><E><H><M><E><P><A><G><E...
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.<BOP>
Q3IHJ4
Q1R0H5
RL3_CHRSD
50S ribosomal protein L3
Chromohalobacter
<M><T><I><G><L><V><G><K><K><S><G><M><T><R><I><F><T><E><N><G><A><S><V><P><V><T><V><I><E><V><E><P><N><R><V><T><R><V><K><T><V><E><S><D><G><Y><S><A><V><Q><V><T><S><G><S><R><K><A><K><H><L><T><K><A><A><A><G><Q><Y><A><K><S><G><V><E><A><G><R><S><L><M><E><F><R><L><A><E><G><E><E><A><P><E><V><G><G><N><I><T><V><S><L><F><E><A><G><Q...
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP>
Q1R0H5
B6Q3C6
3DHQ_TALMQ
3-dehydroquinate dehydratase
Talaromyces sect. Talaromyces
<M><P><T><I><L><I><L><N><G><P><N><L><N><L><L><G><L><R><E><P><H><I><Y><G><S><T><T><L><Q><D><V><E><N><I><C><I><E><L><G><K><Q><H><N><V><T><V><D><A><F><Q><S><N><H><E><G><Q><L><I><D><R><I><H><E><A><R><N><K><V><D><L><I><V><I><N><P><A><A><Y><T><H><T><S><V><A><I><R><D><A><L><L><G><V><S><I><P><F><I><E><V><H><I><S><N><V><H><A><R...
Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.<BOP>
B6Q3C6
P60704
ABEC3_CRILO
DNA dC->dU-editing enzyme APOBEC3
Cricetulus
<M><G><P><F><C><L><G><C><S><H><R><K><C><Y><S><P><I><R><N><L><I><S><Q><E><T><F><K><F><H><F><K><N><L><G><Y><A><K><G><R><K><D><T><F><L><C><Y><E><V><T><R><K><D><C><D><S><P><V><S><L><H><H><G><V><F><K><N><K><G><N><I><H><A><E><V><C><F><L><Y><W><F><H><D><K><V><L><K><V><L><S><P><R><E><E><F><K><I><T><W><Y><M><S><W><S><P><C><F><E...
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA.<BOP>
P60704
Q6D1U0
TRMD_PECAS
tRNA [GM37] methyltransferase
Pectobacterium
<M><W><I><G><V><I><S><L><F><P><E><M><F><R><A><I><T><D><F><G><V><T><G><R><A><V><K><N><G><L><L><N><V><Q><Y><W><S><P><R><D><F><T><Y><D><R><H><R><T><V><D><D><R><P><Y><G><G><G><P><G><M><L><M><M><V><Q><P><L><R><D><A><I><H><A><A><K><A><A><A><G><E><G><A><R><V><I><Y><L><S><P><Q><G><R><K><L><D><Q><Q><G><V><R><Q><L><A><T><N><Q><K...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
Q6D1U0
Q4KBI1
RNH_PSEF5
Ribonuclease H
Pseudomonas
<M><S><D><S><V><E><I><F><T><D><G><A><C><K><G><N><P><G><P><G><G><W><G><A><L><L><V><C><K><G><V><E><K><E><L><W><G><G><E><A><N><T><T><N><N><R><M><E><L><M><A><A><I><R><G><L><E><E><L><K><R><Q><C><D><V><Q><L><V><T><D><S><Q><Y><V><M><K><G><I><N><E><W><M><A><N><W><K><K><R><G><W><K><T><A><A><K><E><P><V><K><N><A><D><L><W><Q><Q><L...
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP>
Q4KBI1
Q82TF6
RECA_NITEU
Recombinase A
Nitrosomonas
<M><D><E><N><K><N><K><A><L><S><A><A><L><A><Q><I><E><K><Q><Y><G><K><G><S><I><M><R><L><G><D><S><D><V><A><K><D><I><Q><V><V><S><T><G><S><L><G><L><D><I><A><L><G><V><G><G><L><P><R><G><R><I><I><E><I><Y><G><P><E><S><S><G><K><T><T><L><T><L><Q><A><I><A><E><M><Q><K><L><G><G><T><A><A><F><I><D><A><E><H><A><L><D><P><Q><Y><A><Q><K><I...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
Q82TF6
P59407
NANA_LACPL
Sialic acid lyase
Lactiplantibacillus
<M><S><K><K><L><L><Y><A><A><Q><M><T><A><F><D><K><D><G><N><I><N><L><D><G><I><R><A><L><V><R><Y><N><I><D><V><N><K><V><D><G><L><Y><V><C><G><S><T><G><E><A><F><M><L><N><T><D><E><K><K><Q><V><M><E><T><V><Y><D><E><A><N><G><A><I><D><L><V><A><Q><V><G><S><L><N><L><K><E><A><K><E><L><A><K><F><A><T><D><L><G><Y><P><K><L><S><A><V><T><P...
Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.<BOP>
P59407
Q9Y933
GUAA_AERPE
Glutamine amidotransferase
Aeropyrum
<M><A><K><T><L><D><S><P><G><V><L><V><V><D><F><G><G><Q><Y><A><H><L><I><A><R><R><I><R><E><L><G><V><Y><S><E><I><V><P><A><T><S><L><D><A><L><G><E><A><L><P><R><A><A><G><V><V><L><S><G><G><P><G><S><V><W><G><S><R><H><D><E><A><A><A><M><V><L><Q><L><G><K><P><V><L><G><I><C><Y><G><H><Q><L><L><A><K><V><L><G><G><E><V><G><R><S><P><L><P...
Catalyzes the synthesis of GMP from XMP.<BOP>
Q9Y933
A4QJJ7
RR14_AETGR
30S ribosomal protein S14, chloroplastic
Aethionema
<M><A><K><K><S><L><I><Y><R><E><K><K><R><Q><K><L><E><E><K><Y><H><L><I><R><R><S><S><K><K><E><I><S><Q><I><P><S><L><S><E><K><W><K><I><H><G><K><L><Q><S><P><P><R><N><S><A><P><T><R><L><H><R><R><C><F><S><T><G><R><P><R><A><N><Y><R><D><F><G><L><S><G><H><I><L><R><E><M><V><H><A><C><L><L><P><G><A><T><R><S><S><W>
Binds 16S rRNA, required for the assembly of 30S particles.<BOP>
A4QJJ7
A5GJ87
RECO_SYNPW
Recombination protein O
unclassified Synechococcus
<M><S><G><D><R><R><L><Q><G><L><A><L><K><V><G><P><L><G><E><H><D><R><L><L><T><L><L><S><D><D><V><G><V><V><R><L><A><V><P><G><A><R><R><P><R><S><S><L><A><A><A><V><P><L><T><C><L><D><L><Q><V><V><G><R><R><G><L><A><R><V><R><Q><L><R><V><L><R><S><Y><S><G><L><G><Q><R><L><D><T><L><A><S><A><Q><A><L><A><E><L><A><I><A><L><V><S><S><D><D...
Involved in DNA repair and RecF pathway recombination.<BOP>
A5GJ87
C4K906
ATPD_HAMD5
F-type ATPase subunit delta
Candidatus Hamiltonella
<M><S><M><A><T><I><A><R><P><Y><A><K><A><I><F><D><F><A><V><E><H><H><S><I><E><H><W><Q><N><M><L><A><F><S><A><Q><V><S><A><H><K><Q><V><T><Q><W><L><S><G><V><M><H><S><E><K><T><A><Q><I><F><I><S><L><C><S><D><H><L><D><E><F><S><K><N><F><I><K><I><M><A><Q><N><G><R><L><S><L><L><P><E><V><L><K><Q><F><M><A><L><R><A><M><I><N><S><V><I><D...
This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.<BOP>
C4K906
P28008
PTMCB_STACA
PTS system mannitol-specific EIIB component
Staphylococcus
<M><D><T><M><S><N><S><Q><Q><N><K><G><I><G><R><K><V><Q><A><F><G><S><F><L><S><S><M><I><M><P><N><I><G><A><F><I><A><W><G><F><I><A><A><I><F><I><D><N><G><W><F><P><N><K><D><L><A><Q><L><A><G><P><M><I><T><Y><L><I><P><L><L><I><A><F><S><G><G><R><L><I><H><D><L><R><G><G><I><I><A><A><T><A><T><M><G><V><I><V><A><L><P><D><T><P><M><L><L...
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport.<BOP...
P28008
B8F4Q2
SUCC_GLAP5
Succinyl-CoA synthetase subunit beta
Glaesserella
<M><N><L><H><E><Y><Q><G><K><Q><I><F><A><K><Y><K><L><P><V><S><Q><G><I><A><C><K><T><A><D><E><A><V><E><A><I><K><Q><L><K><G><D><A><W><A><I><K><C><Q><V><H><A><G><G><R><G><K><A><G><G><V><K><L><V><R><N><E><A><E><V><R><E><F><A><D><K><W><L><G><K><R><L><V><T><F><Q><T><D><A><N><G><Q><P><V><N><T><L><Y><V><E><E><T><A><G><I><A><R><E...
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinat...
B8F4Q2
A1A1I6
HIS3_BIFAA
Phosphoribosyl-AMP cyclohydrolase
Bifidobacterium
<M><T><N><E><A><Y><D><N><T><T><T><L><D><P><R><I><A><Q><R><L><K><H><D><D><K><G><L><V><A><A><V><I><Q><Q><F><D><T><K><E><V><L><M><V><G><Y><M><N><D><E><A><I><R><R><T><L><T><T><G><R><V><T><F><W><S><R><S><R><Q><E><Y><W><R><K><G><D><T><S><G><H><A><Q><Y><V><K><S><F><A><L><D><C><D><G><D><A><I><L><V><E><V><D><Q><V><G><A><A><C><H...
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.<BOP>
A1A1I6
P11483
ACM3_PIG
null
Sus
<M><T><L><H><N><N><N><T><T><S><P><L><F><P><N><I><S><S><S><W><I><H><G><P><S><D><A><G><L><P><P><G><T><V><T><H><F><G><S><Y><N><I><S><Q><A><A><G><N><F><S><S><P><N><G><T><T><S><D><P><L><G><G><H><T><I><W><Q><V><V><F><I><A><F><L><T><G><I><L><A><L><V><T><I><I><G><N><I><L><V><I><V><A><F><K><V><N><K><Q><L><K><T><V><N><N><Y><F><L...
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.<BOP>
P11483
Q97XW1
GLPK1_SACS2
Glycerokinase 1
Saccharolobus
<M><N><T><M><S><H><K><F><V><L><A><L><D><E><G><T><T><S><A><R><A><I><L><F><D><S><D><L><N><I><V><N><I><G><Q><Y><E><F><P><Q><Y><Y><P><Q><P><G><Y><V><E><H><D><P><E><E><I><W><E><A><Q><M><L><A><V><K><K><A><I><S><K><I><D><A><K><Q><I><V><A><I><G><I><T><N><Q><R><E><T><T><V><L><W><D><A><K><S><G><K><P><V><Y><N><A><I><V><W><Q><D><R...
Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.<BOP>
Q97XW1
P82807
FAXD1_NOTSC
Notecarin-D1 heavy chain
Notechis
<M><A><P><Q><L><L><L><C><L><I><L><T><F><L><W><S><L><P><E><A><E><S><N><V><F><L><K><S><K><V><A><N><R><F><L><Q><R><T><K><R><S><N><S><L><F><E><E><I><R><P><G><N><I><E><R><E><C><I><E><E><K><C><S><K><E><E><A><R><E><V><F><E><D><N><E><K><T><E><T><F><W><N><V><Y><V><D><G><D><Q><C><S><S><N><P><C><H><Y><R><G><T><C><K><D><G><I><G><S...
Snake prothrombin activator that attacks the hemostatic system of prey. This protein is functionally similar to blood coagulation factor Xa.<BOP>
P82807
A8M8Q9
LYSY_CALMQ
Putative [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase
Caldivirga
<M><R><R><A><C><I><I><G><A><S><G><V><I><G><G><E><L><L><R><L><L><L><G><H><N><N><V><E><V><V><C><A><T><S><R><R><F><A><G><E><F><I><Y><R><V><H><P><N><L><R><G><F><I><N><L><K><F><T><Q><P><S><I><D><A><V><L><K><S><E><S><D><V><V><F><L><A><L><P><H><G><E><S><V><K><W><V><P><K><L><V><E><S><G><L><L><A><I><D><L><S><A><D><F><R><L><K><N...
Involved in both the arginine and lysine biosynthetic pathways.<BOP>
A8M8Q9
Q9HE00
MTX1_SCHPO
Metaxin-1
Schizosaccharomyces
<M><G><G><L><T><K><F><S><S><Y><F><H><S><I><F><S><R><F><P><L><I><T><F><S><N><P><Y><P><G><E><N><E><D><Y><K><T><K><T><V><M><Y><L><T><M><W><N><S><D><L><N><S><E><A><L><D><V><N><S><L><Q><W><Q><T><W><A><K><L><N><D><P><S><I><V><F><L><N><V><S><N><H><A><S><P><D><E><K><V><P><F><I><Q><I><E><S><R><K><L><V><L><N><P><S><L><L><Q><Y><F...
Involved in transport of proteins into the mitochondrion.<BOP>
Q9HE00
A6LPT0
RL15_CLOB8
50S ribosomal protein L15
Clostridium
<M><K><L><H><E><L><K><P><A><A><G><S><K><K><A><P><K><R><I><G><R><G><T><G><S><G><L><G><R><N><A><G><K><G><E><K><G><Q><N><A><R><S><G><G><G><V><R><P><G><F><E><G><G><Q><M><P><L><Y><R><R><L><P><K><R><G><F><T><N><I><F><A><K><K><I><V><S><I><N><L><D><R><L><N><I><F><E><N><G><T><E><V><T><P><E><L><L><L><E><R><R><V><V><S><K><V><L><D...
Binds to the 23S rRNA.<BOP>
A6LPT0
Q8W9F5
CYB_NAPIN
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Napaeozapus
<M><I><N><I><R><K><K><H><P><L><M><K><I><L><N><E><S><F><I><D><L><P><T><P><C><N><I><S><S><W><W><N><F><G><S><F><L><G><A><C><L><A><I><Q><I><L><T><G><L><F><L><A><M><H><Y><T><S><D><T><T><T><A><F><S><S><V><T><H><I><C><R><D><V><N><Y><G><W><L><I><R><Y><L><H><A><N><G><A><S><M><F><F><I><C><L><F><L><H><V><G><R><G><L><Y><Y><G><S><Y...
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is...
Q8W9F5
Q8YAB4
ISPF_LISMO
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Listeria
<M><I><R><I><G><Q><G><Y><D><V><H><K><L><A><Y><D><R><D><L><I><I><G><G><V><K><I><P><Y><E><K><G><L><L><G><H><S><D><A><D><V><L><L><H><A><I><T><D><A><I><I><G><A><I><G><A><G><D><I><G><H><F><F><P><D><T><D><M><V><F><K><D><A><D><S><A><E><L><L><A><E><I><W><Q><K><V><E><A><D><G><F><R><L><G><N><L><D><A><T><I><I><A><E><K><P><K><M><A...
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a correspond...
Q8YAB4
Q17WZ6
MURA_HELAH
UDP-N-acetylglucosamine enolpyruvyl transferase
Helicobacter
<M><D><F><L><E><I><V><G><Q><I><P><L><K><G><G><V><E><I><S><G><A><K><N><S><A><L><P><I><L><A><A><T><L><L><S><Q><Q><E><V><T><I><S><A><L><P><Q><V><A><D><I><K><A><M><A><S><L><L><Q><N><L><G><A><E><L><D><W><F><N><S><H><T><L><K><L><C><A><K><S><L><R><H><T><E><A><T><Y><D><L><V><R><K><M><R><A><S><I><L><V><L><G><P><L><L><A><R><F><K...
Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.<BOP>
Q17WZ6
Q8DKG1
COAE_THEVB
Dephosphocoenzyme A kinase
Thermosynechococcus
<M><S><R><L><L><R><L><G><I><T><G><G><I><A><C><G><K><S><V><V><A><G><Y><L><Q><R><Q><Y><G><V><P><I><V><D><A><D><V><L><A><R><Q><V><V><A><V><G><T><P><I><Y><Q><A><I><V><D><R><Y><G><D><G><I><C><R><R><D><G><T><L><D><R><S><R><L><G><E><I><V><F><A><Q><P><Q><E><R><Q><W><L><E><A><Q><I><H><P><A><V><V><A><E><M><E><Q><A><M><A><T><C><D...
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.<BOP>
Q8DKG1
Q72B11
MNMG_DESVH
Glucose-inhibited division protein A
Desulfovibrio
<M><S><T><I><R><K><P><S><P><P><D><M><Y><D><C><I><V><V><G><A><G><H><A><G><C><E><A><A><M><A><L><A><R><M><G><H><A><T><L><L><L><T><G><N><A><D><R><I><G><H><L><S><C><N><P><A><I><G><G><L><A><K><G><H><M><V><K><E><I><D><A><L><G><G><M><M><G><L><W><A><D><E><A><G><I><Q><F><R><T><L><N><S><S><K><G><P><A><V><R><A><T><R><A><Q><I><D><R...
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP>
Q72B11
B6YTR4
DNLI_THEON
TNA1_lig
Thermococcus
<M><G><D><M><K><Y><T><E><L><S><D><L><Y><R><R><L><E><K><T><T><L><K><T><L><K><T><K><F><V><A><D><F><L><K><K><T><P><D><E><L><L><E><V><V><P><Y><L><I><L><G><K><V><F><P><D><W><D><E><R><E><L><G><V><G><E><K><L><L><I><K><A><V><S><M><A><T><G><V><Q><E><R><E><I><E><N><S><V><K><D><T><G><D><L><G><E><S><V><A><L><A><L><K><K><K><K><Q><K...
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Can use both ATP and NAD(+), but NAD(+) may be a preferred nucleotide cofactor.<BOP>
B6YTR4
P09839
HBA_MACCA
Hemopressin
Macrotus
<V><L><S><A><A><D><K><G><N><V><K><A><A><W><D><K><V><G><G><Q><A><G><E><Y><G><A><E><A><L><E><R><M><F><L><S><F><P><T><T><K><T><Y><F><P><H><F><D><L><A><H><G><S><A><Q><V><K><G><H><G><K><K><V><A><D><A><L><T><N><A><V><G><H><M><D><D><L><P><G><A><L><S><A><L><S><D><L><H><A><Y><K><L><R><V><D><P><V><N><F><K><L><L><S><H><C><L><L><V...
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1. Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.<BOP>
P09839
P21697
PLAS_SYNY3
Plastocyanin
unclassified Synechocystis
<M><S><K><K><F><L><T><I><L><A><G><L><L><L><V><V><S><S><F><F><L><S><V><S><P><A><A><A><A><N><A><T><V><K><M><G><S><D><S><G><A><L><V><F><E><P><S><T><V><T><I><K><A><G><E><E><V><K><W><V><N><N><K><L><S><P><H><N><I><V><F><A><A><D><G><V><D><A><D><T><A><A><K><L><S><H><K><G><L><A><F><A><A><G><E><S><F><T><S><T><F><T><E><P><G><T><Y...
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.<BOP>
P21697
Q0HJ64
OPGG_SHESM
Glucans biosynthesis protein G
Shewanella
<M><V><S><L><L><R><C><Q><S><F><K><P><S><S><S><L><I><C><S><L><A><L><S><A><A><F><A><L><S><S><S><A><F><A><E><E><T><K><P><A><E><N><K><P><A><T><P><V><V><S><P><P><K><A><T><A><Q><P><A><N><K><N><Q><V><R><F><T><K><T><G><T><F><D><G><D><S><V><V><K><L><A><R><K><L><A><S><K><P><Y><V><V><L><K><D><P><L><P><A><G><L><A><K><L><S><Y><D><E...
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).<BOP>
Q0HJ64
A4VI15
TRMA_PSEU5
tmRNA (uracil(341)-C(5))-methyltransferase
Pseudomonas
<M><P><L><P><Q><L><D><P><A><Q><Y><A><A><Q><L><A><E><K><A><A><R><L><E><E><L><L><A><P><F><D><A><P><A><A><E><V><F><D><S><P><R><E><H><Y><R><L><R><A><E><F><R><L><W><R><E><G><G><Q><R><H><Y><A><M><F><E><Q><G><D><K><H><K><A><I><L><I><D><D><F><P><I><A><S><R><R><I><N><E><L><M><P><Q><L><K><A><A><W><Q><A><S><E><V><L><S><F><K><L><F...
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).<BOP>
A4VI15
C5CSH5
LEUC_VARPS
Isopropylmalate isomerase
Variovorax
<M><A><R><T><L><Y><D><K><I><W><D><E><H><V><V><H><T><E><E><D><G><T><A><I><L><Y><I><D><R><H><L><V><H><E><V><T><S><P><Q><A><F><E><G><L><R><E><A><G><R><K><L><W><R><I><S><S><V><V><A><T><A><D><H><N><T><P><T><T><G><W><E><R><G><Y><E><G><I><A><D><P><T><S><K><E><Q><V><T><T><L><D><K><N><I><A><E><F><G><A><A><A><F><F><P><F><L><S><K...
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP>
C5CSH5
Q9SHH7
GSTUP_ARATH
GST class-tau member 25
Arabidopsis
<M><A><D><E><V><I><L><L><D><F><W><P><S><M><F><G><M><R><T><R><I><A><L><E><E><K><N><V><K><F><D><Y><R><E><Q><D><L><W><N><K><S><P><I><L><L><E><M><N><P><V><H><K><K><I><P><V><L><I><H><N><G><N><P><V><C><E><S><L><I><Q><I><E><Y><I><D><E><V><W><P><S><K><T><P><L><L><P><S><D><P><Y><Q><R><A><Q><A><K><F><W><G><D><F><I><D><K><K><V><Y...
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.<BOP>
Q9SHH7
Q0AUM4
ARGB_SYNWW
NAG kinase
Syntrophomonas
<M><I><V><S><A><M><E><K><A><E><I><L><V><E><A><L><P><Y><I><K><D><F><Y><G><R><R><V><V><I><K><Y><G><G><A><A><M><T><D><C><E><L><K><Q><K><V><M><Q><D><I><V><L><M><K><F><V><G><M><H><P><I><V><V><H><G><G><G><P><E><I><N><Q><M><L><S><R><L><G><I><Q><S><E><F><V><N><G><F><R><V><T><D><A><A><T><M><E><I><V><E><M><V><L><G><G><K><V><N><K...
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.<BOP>
Q0AUM4
O01671
SXL_MEGSC
Sex-lethal homolog
Megaselia
<M><Y><R><G><G><R><M><W><G><M><S><H><S><L><P><S><G><M><S><S><Y><A><F><S><P><Q><D><T><D><F><S><S><Y><P><S><T><I><G><R><Q><H><S><Q><Q><S><Q><R><Y><Y><Q><N><N><N><C><G><L><G><S><V><G><N><M><A><N><S><T><N><S><L><N><S><G><T><N><N><S><G><T><N><L><I><V><N><Y><L><P><Q><D><M><Q><D><R><E><L><Y><S><L><F><R><T><I><G><P><I><N><T><C...
Unknown; apparently not involved in somatic sex determination.<BOP>
O01671
Q8WHM4
MATK_LEMMN
Intron maturase
Lemna
<M><E><D><F><K><G><Y><L><Q><K><G><G><F><K><Q><Q><H><L><L><Y><P><L><L><F><Q><E><Y><I><Y><A><L><A><H><D><Q><G><L><N><V><N><A><S><T><F><N><E><P><P><E><I><S><G><Y><D><K><K><Y><S><S><L><L><V><K><R><L><I><N><R><L><Y><Q><Q><N><T><F><I><H><S><V><N><N><S><K><D><N><R><F><V><G><H><N><K><N><F><Y><Y><Q><M><I><S><E><A><F><A><I><V><V...
Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns.<BOP>
Q8WHM4
Q823F3
RBFA_CHLCV
Ribosome-binding factor A
Chlamydia
<M><T><E><N><R><R><I><K><K><V><N><S><L><L><R><E><A><I><A><N><V><I><L><K><D><V><K><H><P><K><I><S><N><Q><W><I><T><V><T><R><V><C><L><S><K><D><L><H><S><A><R><V><Y><V><S><I><M><P><H><E><N><T><S><A><E><T><L><D><A><L><K><A><S><A><G><F><I><A><Y><K><A><S><K><G><V><V><L><K><Y><F><P><E><I><H><F><Y><I><E><D><I><F><S><P><Q><D><H><I...
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli...
Q823F3
B1M1U6
RLMN_METRJ
tRNA m2A37 methyltransferase
Methylobacterium
<M><A><T><P><S><L><D><S><A><R><A><A><D><A><A><I><E><K><A><P><D><L><L><P><E><A><L><P><G><R><R><P><S><L><V><G><L><T><R><D><A><L><K><A><Q><L><I><G><M><G><V><P><E><R><E><S><R><M><R><A><G><Q><V><W><H><W><V><N><F><R><G><A><S><D><F><A><E><M><T><N><V><G><K><A><L><K><A><Q><L><A><E><H><F><T><L><E><R><P><E><V><A><S><R><Q><V><S><R...
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.<BOP>
B1M1U6
C3XR70
ENOPH_BRAFL
2,3-diketo-5-methylthio-1-phosphopentane phosphatase
Branchiostoma
<M><S><D><S><R><L><R><R><R><Q><G><T><A><G><T><D><N><K><R><R><A><D><G><P><H><D><I><S><G><L><L><D><G><V><S><V><V><L><L><D><I><E><G><T><T><T><P><I><T><F><V><K><D><E><L><F><P><Y><V><C><S><H><V><R><Q><H><L><E><E><H><W><K><E><E><E><C><Q><E><D><I><A><A><L><R><K><Q><A><K><E><D><K><E><M><D><G><V><V><L><I><P><E><C><T><T><K><D><D...
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).<BOP>
C3XR70
A8EQW9
SYE1_ALIB4
Glutamyl-tRNA synthetase 1
Aliarcobacter
<M><A><I><T><R><F><A><P><S><P><T><G><Y><L><H><I><G><G><L><R><T><S><L><Y><S><Y><L><W><A><R><K><T><G><G><E><F><R><L><R><I><E><D><T><D><L><A><R><N><S><E><E><A><M><K><A><I><I><D><A><F><D><W><V><G><L><N><Y><D><G><E><V><F><Y><Q><S><K><R><T><D><I><Y><K><Q><Y><I><D><K><L><L><E><S><G><N><A><Y><K><C><Y><M><S><K><E><E><L><D><A><L...
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP>
A8EQW9
Q4AAX4
END4_MESHJ
Endonuclease IV
Mesomycoplasma
<M><I><K><I><G><S><H><V><R><F><R><K><P><D><Y><L><F><G><A><I><Q><E><S><L><E><N><K><A><N><T><A><M><I><F><L><G><P><P><Q><S><T><F><R><V><K><P><E><N><Y><K><L><Q><D><Y><Q><K><H><F><F><K><Q><I><P><P><E><D><I><I><V><H><A><P><Y><I><I><N><P><A><S><P><I><K><A><Q><F><S><N><D><F><L><V><K><E><I><E><K><I><N><Y><I><G><A><K><F><L><V><L...
Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.<BOP>
Q4AAX4
Q5R504
F162A_PONAB
E2-induced gene 5 protein homolog
Pongo
<M><G><S><L><S><G><L><R><L><A><A><G><S><C><F><R><L><C><E><R><D><V><F><S><S><L><R><L><T><R><S><S><D><L><K><R><I><N><G><F><C><T><K><P><Q><E><S><P><R><A><P><S><R><T><Y><N><R><V><P><L><H><K><P><T><E><W><Q><K><K><I><L><V><W><S><G><R><F><K><K><E><D><E><I><P><E><T><V><S><L><E><M><L><D><T><A><K><N><K><M><R><V><K><I><S><Y><L><M...
Proposed to be involved in regulation of apoptosis; the exact mechanism may differ between cell types/tissues. May be involved in hypoxia-induced cell death of transformed cells implicating cytochrome C release and caspase activation (such as CASP9) and inducing mitochondrial permeability transition. May be involved in...
Q5R504
Q8RAE4
AROQ_CALS4
Type II DHQase
Caldanaerobacter
<M><K><R><V><L><V><I><H><G><P><N><V><N><L><T><G><K><R><E><K><E><V><Y><G><E><I><T><F><E><E><I><N><N><M><I><K><R><E><A><A><K><L><D><I><A><V><K><I><Q><Q><S><N><S><E><G><E><I><I><N><L><I><H><S><A><E><N><N><F><D><A><I><I><I><N><P><A><A><Y><T><H><Y><S><L><A><I><M><D><A><I><A><S><V><S><V><P><V><I><E><V><H><I><S><N><I><F><G><R...
Catalyzes a trans-dehydration via an enolate intermediate.<BOP>
Q8RAE4
Q0AUI3
RL2_SYNWW
50S ribosomal protein L2
Syntrophomonas
<M><G><I><K><K><F><K><P><T><T><P><S><R><R><H><M><T><T><M><S><F><E><E><I><T><K><Q><E><P><E><K><S><L><I><A><P><L><K><R><K><A><G><R><N><V><K><G><R><I><T><V><R><H><R><G><G><G><H><K><R><Q><Y><R><I><V><D><F><R><R><V><K><D><N><V><P><A><R><V><A><A><I><E><Y><D><P><N><R><S><A><H><I><A><L><L><H><Y><F><D><G><H><K><A><Y><I><I><A><P...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
Q0AUI3
B4SK34
LGT_STRM5
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Stenotrophomonas maltophilia group
<M><I><Y><F><H><D><I><D><P><I><A><L><S><L><G><P><I><K><V><H><W><Y><G><I><M><Y><L><L><G><F><T><A><A><W><L><L><G><R><K><R><I><A><D><G><R><L><P><G><V><D><A><N><G><F><S><D><L><L><F><Y><A><M><L><G><V><V><L><G><G><R><I><G><Y><M><L><F><Y><A><L><G><D><F><L><H><N><P><L><L><L><F><K><V><W><D><G><G><M><S><F><H><G><G><L><L><G><V><I...
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.<BOP>
B4SK34
Q5AQA3
MTND_EMENI
Acireductone dioxygenase (Ni(2+)-requiring)
Aspergillus subgen. Nidulantes
<M><K><A><Y><W><Y><D><N><K><P><G><D><Q><R><E><P><H><D><S><G><R><P><V><S><E><D><Y><L><A><S><L><G><V><I><Y><R><H><F><P><E><L><S><D><V><D><A><L><A><K><E><R><G><Y><K><N><R><D><E><I><T><V><S><P><A><T><M><G><E><A><Y><E><D><K><V><K><M><F><F><A><E><H><L><H><E><D><E><E><I><R><Y><I><R><D><G><E><G><Y><F><D><V><R><G><K><E><D><E><W...
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine...
Q5AQA3
A1UHM2
BIOD_MYCSK
Dethiobiotin synthase
unclassified Mycobacterium
<M><S><V><L><V><I><T><G><T><D><T><G><V><G><K><T><V><A><T><A><A><L><A><C><A><A><R><V><A><G><I><D><V><A><V><C><K><P><V><Q><T><G><T><G><P><V><G><G><T><G><D><D><D><L><V><E><I><G><R><L><A><G><V><D><A><L><H><P><G><W><R><Y><P><D><P><L><A><P><V><A><A><A><E><R><A><G><A><A><L><P><T><R><D><E><L><I><G><M><V><R><A><A><D><A><P><G><R...
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.<BOP>
A1UHM2
E3Q897
AMPP2_COLGM
Prolidase
Colletotrichum graminicola species complex
<M><E><T><V><V><D><H><H><V><I><E><V><D><E><F><D><A><L><F><I><E><V><K><T><E><A><A><P><V><E><S><V><V><S><V><A><P><I><P><A><R><F><P><A><K><L><H><A><R><K><I><A><A><E><L><N><A><S><D><G><L><V><F><L><P><G><E><P><S><R><S><Y><E><D><S><D><M><G><P><A><F><R><Q><R><R><Y><F><Y><Y><L><S><G><A><N><F><A><D><C><A><V><T><Y><E><L><A><S><D...
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.<BOP>
E3Q897
B2IVX7
TRHO_NOSP7
tRNA hydroxylation protein O
Nostoc
<M><N><S><E><N><T><Q><I><V><A><A><L><Y><K><F><V><K><L><P><D><F><A><Q><K><R><D><P><L><L><S><Y><C><Q><A><Q><G><V><K><G><T><I><L><L><A><Q><E><G><I><N><G><T><I><A><G><S><R><Q><A><I><D><S><V><L><W><F><L><R><S><D><P><R><L><A><D><L><E><Y><K><E><S><Y><T><E><T><P><P><F><E><R><M><K><V><R><L><K><S><E><I><V><T><L><G><L><P><E><I><D...
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP>
B2IVX7
P25974
GLCB1_SOYBN
Beta-conglycinin beta subunit
Glycine subgen. Soja
<M><M><R><V><R><F><P><L><L><V><L><L><G><T><V><F><L><A><S><V><C><V><S><L><K><V><R><E><D><E><N><N><P><F><Y><L><R><S><S><N><S><F><Q><T><L><F><E><N><Q><N><G><R><I><R><L><L><Q><R><F><N><K><R><S><P><Q><L><E><N><L><R><D><Y><R><I><V><Q><F><Q><S><K><P><N><T><I><L><L><P><H><H><A><D><A><D><F><L><L><F><V><L><S><G><R><A><I><L><T><L...
Seed storage protein. Accumulates during seed development and is hydrolyzed after germination to provide a carbon and nitrogen source for the developing seedling.<BOP>
P25974
Q6FPE8
RFT1_CANGA
Oligosaccharide translocation protein RFT1
Nakaseomyces/Candida clade
<M><S><G><A><D><I><L><E><K><T><T><R><G><A><T><F><L><M><M><G><Q><L><F><S><K><I><V><T><F><L><L><N><N><T><L><V><R><Y><L><S><P><R><I><F><G><I><T><A><F><L><E><F><I><V><G><T><V><L><F><F><S><R><E><A><I><R><L><S><T><Q><R><I><A><D><G><N><D><A><D><N><D><H><D><H><D><R><D><D><S><A><L><Q><V><C><V><N><F><A><M><I><P><L><F><I><G><I><P...
May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.<BOP>
Q6FPE8
A8WQT4
MICU1_CAEBR
Calcium uptake protein 1 homolog, mitochondrial
Caenorhabditis
<M><L><R><H><N><F><R><S><S><I><F><I><R><I><V><A><N><S><W><S><I><T><R><S><V><S><S><A><P><I><K><A><E><S><R><K><Q><Q><D><S><L><K><N><I><D><S><G><E><A><Y><T><A><L><G><N><I><R><Q><K><K><D><V><F><H><Y><T><D><R><A><S><G><T><G><Y><S><H><Y><S><N><S><V><Y><Q><H><R><P><Y><I><W><P><P><L><R><K><M><Y><N><W><N><Y><A><F><V><I><A><G><M...
Key regulator of mitochondrial calcium uniporter (MCU).<BOP>
A8WQT4
P25278
YC2M_HERAU
ORFC
Herpetosiphon
<M><M><I><E><S><V><A><I><S><V><K><E><S><M><P><P><Q><V><S><V><E><I><N><G><M><L><N><D><G><C><T><A><F><H><E><A><K><Q><S><I><D><G><N><T><I><K><I><E><V><T><T><I><R><P><K><D><A><M><C><N><Q><Q><I><S><P><F><S><T><I><I><Q><I><E><G><E><L><K><P><G><E><Y><T><I><L><V><N><D><V><A><E><A><L><K><L>
Could be a silencing control element for the regulation of the restriction system.<BOP>
P25278
A5ERG8
TILS_BRASB
tRNA(Ile)-lysidine synthetase
unclassified Bradyrhizobium
<M><S><T><G><Q><S><E><D><H><L><P><I><S><A><A><E><A><E><R><L><F><A><P><F><A><D><S><G><V><L><T><L><A><V><S><G><G><P><D><S><M><A><L><M><W><L><A><A><R><W><R><A><T><R><A><G><G><P><R><L><L><A><V><T><V><D><H><G><L><R><P><E><S><R><R><E><A><L><M><V><K><Q><L><A><R><Q><L><G><L><T><H><R><T><L><R><W><S><G><E><K><P><A><A><G><I><P><E...
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP>
A5ERG8
Q92564
DCNL4_HUMAN
Defective in cullin neddylation protein 1-like protein 4
Homo
<M><H><S><D><A><A><A><V><N><F><Q><L><N><S><H><L><S><T><L><A><N><I><H><K><I><Y><H><T><L><N><K><L><N><L><T><E><D><I><G><Q><D><D><H><Q><T><G><S><L><R><S><C><S><S><S><D><C><F><N><K><V><M><P><P><R><K><K><R><R><P><A><S><G><D><D><L><S><A><K><K><S><R><H><D><S><M><Y><R><K><Y><D><S><T><R><I><K><T><E><E><E><A><F><S><S><K><R><C><L...
Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which are necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs).<BOP>
Q92564
O74876
MU135_SCHPO
Meiotically up-regulated gene 135 protein
Schizosaccharomyces
<M><S><E><E><D><N><R><L><N><E><L><F><A><N><D><L><G><V><Q><P><P><C><E><R><S><L><K><E><G><R><R><F><L><N><D><F><E><I><A><A><K><K><K><L><L><E><L><E><R><K><A><L><E><D><K><E><K><N><L><N><F><V><V><E><S><E><R><T><L><F><N><S><K><K><R><A><F><D><N><D><E><C><Y><N><D><R><C><K><L><F><R><G><I><V><N><E><W><G><R><S><E><R><T><L><D><S><L...
Has a role in meiosis.<BOP>
O74876
Q8DD27
EFTU1_VIBVU
Elongation factor Tu 1
Vibrio
<M><S><K><E><K><F><E><R><V><K><P><H><V><N><V><G><T><I><G><H><V><D><H><G><K><T><T><L><T><A><A><I><C><T><T><L><A><K><V><Y><G><G><A><A><R><D><F><A><S><I><D><N><A><P><E><E><R><E><R><G><I><T><I><S><T><S><H><V><E><Y><D><T><P><A><R><H><Y><A><H><V><D><C><P><G><H><A><D><Y><V><K><N><M><I><T><G><A><A><Q><M><D><G><G><I><L><V><V><A...
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP>
Q8DD27
Q91V12
BACH_MOUSE
Long chain acyl-CoA thioester hydrolase
Mus
<M><K><L><L><V><G><T><L><R><L><W><E><V><G><R><Q><V><A><F><S><S><L><T><P><G><Q><E><C><S><G><L><R><K><T><F><W><A><A><M><R><A><V><R><T><R><A><D><H><Q><K><L><G><H><C><V><T><M><G><R><I><M><R><P><D><D><A><N><V><A><G><N><V><H><G><G><T><I><L><K><M><I><E><E><A><G><A><I><I><S><T><R><H><C><N><S><Q><N><G><E><R><C><V><A><A><L><A><R...
Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (Probable). Preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18 (Probable). May play an important physiologic...
Q91V12
P24709
INVO_CEBAL
Involucrin
Cebus
<M><S><Q><Q><H><T><L><P><V><T><L><P><P><A><L><S><Q><E><L><L><N><T><V><P><P><P><I><N><T><Q><Q><E><Q><R><E><Q><P><V><P><L><P><P><P><C><Q><K><V><P><V><E><L><P><V><E><G><P><S><K><H><E><E><K><H><V><T><I><V><K><G><V><P><E><H><E><C><E><Q><Q><Q><Q><A><Q><G><Q><E><R><Q><Q><Q><H><W><G><Q><N><K><E><H><Q><K><A><G><N><P><E><Q><Q><L...
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.<BOP>
P24709
A1AR93
GLMM_PELPD
Phosphoglucosamine mutase
Pelobacter
<M><K><K><L><F><G><T><D><G><V><R><G><V><A><N><V><Y><P><M><T><T><E><M><A><M><Q><L><G><R><A><A><A><Y><I><F><K><S><S><S><K><R><R><H><R><I><V><I><G><K><D><T><R><L><S><G><Y><M><L><E><N><A><M><V><A><G><I><C><S><M><G><V><D><V><L><L><V><G><P><L><P><T><P><G><I><A><N><I><T><S><S><M><R><A><D><A><G><V><V><I><S><A><S><H><N><P><F><Q...
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.<BOP>
A1AR93
Q04KB0
EX7L_STRP2
Exodeoxyribonuclease VII large subunit
Streptococcus
<M><E><K><Y><L><S><V><T><T><L><T><K><Y><L><K><M><K><F><D><K><D><P><Y><L><E><R><V><Y><L><T><G><Q><V><S><N><F><R><K><R><P><T><H><Q><Y><F><S><L><K><D><D><H><A><V><I><Q><A><T><I><W><S><G><I><Y><Q><K><L><G><F><D><L><E><E><G><M><K><I><N><V><I><G><R><V><Q><V><Y><E><P><S><G><S><Y><S><I><I><I><E><K><V><E><P><D><G><V><G><A><L><A...
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.<BOP>
Q04KB0
Q9W6S8
SMN1_DANRE
Survival motor neuron protein 1
Danio
<M><A><N><G><A><E><D><V><V><F><C><R><G><T><G><Q><S><D><D><S><D><I><W><D><D><T><A><L><I><K><A><Y><D><K><A><V><A><S><F><K><N><A><L><K><G><E><D><G><A><T><P><Q><E><N><D><N><P><G><K><K><R><K><N><N><K><K><N><K><S><R><K><R><C><N><A><A><P><D><K><E><W><Q><V><G><D><S><C><Y><A><F><W><S><E><D><G><N><L><Y><T><A><T><I><T><S><V><D><Q...
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus . It may also play a role in the metabolism of snoRNPs . Required in motor neurons and proprioceptive neurons to ensure correct U12 intron splicing and proper levels of tmem41b mR...
Q9W6S8
A7X2A2
MURG_STAA1
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
Staphylococcus
<M><T><K><I><A><F><T><G><G><G><T><V><G><H><V><S><V><N><L><S><L><I><P><T><A><L><S><Q><G><Y><E><A><L><Y><I><G><S><K><N><G><I><E><R><E><M><I><E><S><Q><L><P><E><I><K><Y><Y><P><I><S><S><G><K><L><R><R><Y><I><S><L><E><N><A><K><D><V><F><K><V><L><K><G><I><L><D><A><R><K><V><L><K><K><E><K><P><D><L><L><F><S><K><G><G><F><V><S><V><P...
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).<BOP>
A7X2A2
A4T5Y1
GLPK_MYCGI
Glycerokinase
Mycolicibacterium
<M><A><D><F><V><A><A><I><D><Q><G><T><T><S><T><R><C><M><I><F><D><H><D><G><A><E><V><G><R><H><Q><L><E><H><E><Q><I><L><P><K><A><G><W><V><E><H><N><P><V><E><I><W><E><R><T><G><S><V><L><A><T><A><L><N><A><T><K><L><A><T><T><D><L><A><A><L><G><I><T><N><Q><R><E><T><S><L><V><W><N><R><H><T><G><R><P><Y><Y><N><A><I><V><W><Q><D><T><R><T...
Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.<BOP>
A4T5Y1
Q978S3
AROA_THEVO
5-enolpyruvylshikimate-3-phosphate synthase
Thermoplasma
<M><I><V><K><V><S><N><L><G><G><S><G><I><A><E><M><P><S><S><K><S><F><T><Q><R><Y><V><L><A><S><A><F><L><N><K><S><V><V><L><N><G><I><T><I><T><N><D><D><D><V><A><M><R><I><A><E><S><V><G><S><T><I><T><I><N><N><R><S><I><K><I><S><S><N><F><K><C><P><E><E><I><Y><V><G><E><S><G><T><S><Y><R><L><S><I><G><L><L><A><A><S><G><C><V><T><R><I><K...
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.<BOP>
Q978S3
Q9RA35
PLSX_MORMI
Phosphate-acyl-ACP acyltransferase
Moritella
<M><P><N><L><T><I><A><L><D><A><M><G><G><D><F><G><P><H><V><T><I><P><A><A><I><N><I><L><K><K><Y><K><Y><L><S><I><Y><L><V><G><N><E><A><E><I><N><S><L><L><Q><N><T><S><T><S><I><K><S><R><F><T><I><I><P><S><L><D><D><I><P><M><D><L><A><P><A><L><A><L><R><N><F><K><Q><S><S><M><R><M><A><L><N><L><V><R><E><G><K><A><Q><A><C><V><S><A><G><N...
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.<BOP>
Q9RA35
B0T824
DDL_CAUSK
D-alanylalanine synthetase
unclassified Caulobacter
<M><T><P><A><N><P><K><P><L><A><N><H><H><I><A><V><L><L><G><G><P><S><A><E><R><E><V><S><L><V><T><G><A><A><Y><A><A><A><L><E><R><L><G><A><R><V><S><R><V><D><P><G><K><D><V><A><Q><V><L><T><A><L><A><P><D><L><V><F><N><G><L><H><G><R><W><G><E><D><G><C><V><Q><G><V><L><E><T><L><G><L><A><Y><T><H><S><G><V><L><A><S><A><L><A><M><D><K><A...
Cell wall formation.<BOP>
B0T824
Q9QZ59
DMRT1_MOUSE
Doublesex- and mab-3-related transcription factor 1
Mus
<M><P><N><D><D><T><F><G><K><P><S><T><P><T><E><V><P><H><A><P><G><A><P><P><Q><G><K><A><G><G><Y><S><K><A><A><G><A><M><A><G><A><A><G><G><S><G><A><G><G><S><G><G><A><S><G><S><G><P><S><G><L><G><S><G><S><K><K><S><P><R><L><P><K><C><A><R><C><R><N><H><G><Y><A><S><P><L><K><G><H><K><R><F><C><M><W><R><D><C><Q><C><K><K><C><S><L><I><A...
Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allo...
Q9QZ59
D2Y2A0
H13A1_CYRHA
Hainantoxin-XIII
Haplopelma
<M><K><T><A><I><F><T><V><V><L><A><L><A><V><F><A><V><L><S><F><G><W><E><A><N><E><K><A><L><S><E><E><F><T><E><L><I><H><E><K><E><A><A><S><E><T><E><A><R><E><C><R><Y><F><W><G><E><C><H><D><H><M><P><C><C><D><W><L><V><C><R><Y><K><W><P><I><T><Y><N><I><C><V><W><N><R><T><F><P><E><K>
Ion channel inhibitor.<BOP>
D2Y2A0
P40303
PSA4_YEAST
Proteinase YSCE subunit PRE6
Saccharomyces
<M><S><G><Y><D><R><A><L><S><I><F><S><P><D><G><H><I><F><Q><V><E><Y><A><L><E><A><V><K><R><G><T><C><A><V><G><V><K><G><K><N><C><V><V><L><G><C><E><R><R><S><T><L><K><L><Q><D><T><R><I><T><P><S><K><V><S><K><I><D><S><H><V><V><L><S><F><S><G><L><N><A><D><S><R><I><L><I><E><K><A><R><V><E><A><Q><S><H><R><L><T><L><E><D><P><V><T><V><E...
The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu...
P40303
A5GRJ7
DDL_SYNR3
D-alanylalanine synthetase
unclassified Synechococcus
<M><S><S><Q><Q><S><K><V><V><G><L><I><F><G><G><A><S><G><E><H><D><V><S><I><R><S><A><A><T><V><A><E><G><L><S><S><G><A><N><K><E><R><Y><R><V><Q><H><V><Y><I><D><R><Q><G><R><W><W><G><D><A><T><A><R><Q><V><L><S><S><G><Q><A><L><A><D><D><G><S><R><P><G><F><S><G><F><P><D><G><C><L><E><V><E><I><W><Y><P><V><L><H><G><P><N><G><E><D><G><T...
Cell wall formation.<BOP>
A5GRJ7
Q03VF1
TMCAL_LEUMM
tRNA(Met) cytidine acetate ligase
Leuconostoc
<M><Q><A><V><G><I><I><T><E><Y><N><P><F><H><N><G><H><I><Y><H><I><Q><Q><A><K><K><L><T><G><A><D><V><V><V><A><V><M><S><G><N><F><V><Q><R><G><E><P><A><L><F><D><K><W><Q><R><T><Q><M><A><L><E><N><G><V><D><L><V><I><E><L><P><T><F><F><A><V><Q><P><S><H><I><F><A><D><G><A><I><Q><L><L><S><A><L><G><V><D><N><I><V><F><G><S><E><H><P><E><V...
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.<BOP>
Q03VF1
Q1RH84
DUS_RICBR
Probable tRNA-dihydrouridine synthase
belli group
<M><I><K><I><G><N><I><E><L><S><S><N><I><I><L><A><P><M><S><G><V><T><D><L><E><F><R><R><L><V><K><R><F><G><A><G><L><V><V><S><E><M><I><A><S><R><A><M><I><V><E><S><R><Q><S><L><Q><K><C><S><I><M><Q><D><D><A><T><S><A><C><V><Q><L><A><G><C><E><P><N><V><I><A><E><A><A><K><M><N><E><D><M><G><A><K><I><I><D><L><N><F><G><C><P><A><K><K><V...
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.<BOP>
Q1RH84
P44337
ASNC_HAEIN
Regulatory protein AsnC
Haemophilus
<M><H><N><I><D><S><L><D><Q><K><I><L><R><V><L><T><K><D><A><R><T><P><Y><A><E><M><A><K><N><F><G><V><S><P><G><T><I><H><V><R><V><E><K><M><R><Q><S><G><I><I><K><G><T><K><V><I><I><D><E><R><K><L><G><Y><D><V><C><C><F><I><G><I><I><L><K><S><A><K><D><Y><E><K><V><I><K><K><L><E><S><F><D><E><V><V><E><A><Y><Y><T><T><G><N><Y><S><I><F><L...
Activator of asnA transcription.<BOP>
P44337
Q0SHR9
MURD_RHOJR
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Rhodococcus
<M><A><E><E><H><G><G><L><D><W><L><R><G><R><S><V><L><V><A><G><A><G><V><S><G><R><A><T><I><E><P><L><R><D><L><G><A><L><V><T><V><T><D><A><N><V><D><A><L><A><E><C><A><R><L><G><A><A><T><V><P><I><D><D><L><L><A><E><R><D><R><V><A><E><F><A><L><V><V><T><S><P><G><F><R><P><D><A><P><L><L><S><L><A><A><G><D><G><V><P><I><W><G><D><I><E><F...
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).<BOP>
Q0SHR9
Q3B1H3
RL11_CHLL3
50S ribosomal protein L11
Pelodictyon
<M><A><K><K><V><I><G><F><I><K><L><Q><I><P><A><G><A><A><N><P><A><P><P><V><G><P><A><L><G><Q><K><G><V><N><I><M><E><F><C><K><Q><F><N><A><K><T><Q><S><E><A><G><M><I><I><P><V><V><I><T><V><F><S><D><K><S><F><T><F><I><T><K><T><P><P><A><A><V><L><L><L><K><E><A><K><L><Q><K><G><S><G><E><P><N><R><N><K><V><G><T><V><T><R><E><Q><V><K><K...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP>
Q3B1H3
Q5FG91
KTHY_EHRRG
dTMP kinase
Ehrlichia
<M><F><I><T><F><E><G><I><D><G><S><G><K><T><T><Q><S><R><L><L><T><E><Y><L><S><G><V><Y><G><V><D><N><V><I><L><T><R><E><P><G><G><T><F><F><N><E><S><V><R><N><L><L><F><S><T><K><N><L><D><K><L><S><E><L><L><F><F><I><A><M><R><R><E><H><F><M><K><V><I><K><P><A><L><T><Q><Q><K><I><V><I><C><D><R><F><I><D><S><T><I><A><Y><Q><G><Y><G><H><G...
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.<BOP>
Q5FG91
A6T752
SULA_KLEP7
Cell division inhibitor SulA
Klebsiella
<M><F><T><S><A><H><A><N><R><S><A><Q><A><S><A><P><A><G><H><Y><A><H><R><S><G><E><Q><N><T><N><G><L><I><S><E><I><V><Y><R><E><D><Q><P><M><M><T><Q><L><L><L><L><P><L><L><Q><Q><L><G><Q><Q><S><R><W><Q><L><W><L><T><P><Q><Q><K><L><S><R><E><W><V><Q><S><A><G><L><P><L><S><K><V><M><Q><I><S><Q><L><S><P><S><H><T><I><D><S><M><I><R><A><L...
Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventin...
A6T752
B2TW57
NUON_SHIB3
NDH-1 subunit N
Shigella
<M><T><I><T><P><Q><N><L><I><A><L><L><P><L><L><I><V><G><L><T><V><V><V><V><M><L><S><I><A><W><R><R><N><H><F><L><N><A><T><L><S><V><I><G><L><N><A><A><L><V><S><L><W><F><V><G><Q><A><G><A><M><D><V><T><P><L><M><R><V><D><G><F><A><M><L><Y><T><G><L><V><L><L><A><S><L><A><T><C><T><F><A><Y><P><W><L><E><G><Y><N><D><N><K><D><E><F><Y><L...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
B2TW57
Q9KKY0
PPNP_VIBCH
Xanthosine phosphorylase
Vibrio
<M><I><K><E><N><V><Y><F><D><G><N><V><K><S><L><G><F><S><Q><Q><D><G><E><S><T><V><G><V><M><A><P><G><Q><Y><T><F><G><T><G><A><P><E><R><M><T><V><V><K><G><A><L><T><I><K><R><V><T><D><A><D><W><V><T><F><T><A><G><E><A><F><E><V><A><G><N><S><S><F><D><L><Q><V><E><V><A><T><A><Y><L><C><E><F><L><P><A>
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.<BOP>
Q9KKY0