accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
Q2INI7
ISCS_ANADE
Cysteine desulfurase IscS
Anaeromyxobacter
<M><K><I><P><I><Y><M><D><Y><H><A><T><T><P><V><D><P><R><V><L><E><A><M><L><P><Y><F><T><T><E><Y><G><N><A><A><S><K><S><H><A><F><G><W><K><A><E><E><A><V><E><A><A><R><E><E><V><A><K><L><I><G><A><S><A><K><E><I><V><W><T><S><G><A><T><E><S><D><N><L><A><V><K><G><A><A><H><F><Y><Q><A><K><G><K><H><L><V><T><C><K><T><E><H><K><A><V><L><D...
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assemb...
Q2INI7
C3NHA6
RL2_SULIN
50S ribosomal protein L2
Sulfolobus
<M><G><K><N><L><L><Q><Q><R><A><G><K><G><S><P><T><F><R><S><P><S><W><L><R><I><G><K><V><R><Y><P><N><I><F><G><H><L><V><G><K><V><I><D><I><V><H><N><P><G><M><N><T><P><V><A><I><I><K><L><E><N><G><T><K><F><L><T><Q><A><I><Q><G><L><V><I><N><Q><K><I><E><F><G><K><G><S><P><I><A><N><G><N><V><I><E><I><G><D><A><P><E><G><T><I><V><C><N><V...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
C3NHA6
C5DAR2
TYSY_GEOSW
Thymidylate synthase
unclassified Geobacillus
<M><R><Q><Y><L><Q><L><L><E><D><I><L><E><N><G><V><E><K><D><D><R><T><G><V><G><T><L><S><V><F><G><R><Q><L><R><F><N><L><Q><E><G><F><P><L><L><T><T><K><K><L><H><I><R><S><I><I><Y><E><L><L><W><F><L><K><G><D><T><N><V><R><Y><L><Q><E><N><G><V><T><I><W><D><E><W><A><D><E><N><G><D><L><G><P><I><Y><G><A><Q><W><R><S><W><K><G><A><D><G><K...
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell...
C5DAR2
A8RG82
DPES_ENTBW
D-psicose 3-epimerase
Enterocloster
<M><R><Y><F><K><E><E><V><A><G><M><K><Y><G><I><Y><F><A><Y><W><T><K><E><W><F><A><D><Y><K><K><Y><M><D><K><V><S><A><L><G><F><D><V><L><E><I><S><C><A><A><L><R><D><V><Y><T><T><K><E><Q><L><I><E><L><R><E><Y><A><K><E><K><G><L><V><L><T><A><G><Y><G><P><T><K><A><E><N><L><C><S><E><D><P><E><A><V><R><R><A><M><T><F><F><K><D><L><L><P><K...
Involved in the biosynthesis of D-psicose. Catalyzes the reversible epimerization of D-fructose at the C3 position to yield D-psicose. The enzyme is highly specific for D-psicose and shows very low activity with D-tagatose.<BOP>
A8RG82
Q2KYS7
TRHO_BORA1
tRNA hydroxylation protein O
Bordetella
<M><S><I><V><N><I><A><A><Y><K><F><V><S><L><P><D><T><V><L><L><R><E><A><L><Q><E><R><A><D><A><L><G><L><K><G><T><I><L><L><A><P><E><G><I><N><L><F><L><A><G><S><G><E><A><I><E><A><F><L><A><G><L><R><A><D><A><R><F><A><D><I><E><V><K><Y><S><T><S><A><D><V><P><F><G><K><M><R><V><R><L><K><R><E><I><I><R><M><N><H><P><A><I><R><P><E><A><G...
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP>
Q2KYS7
Q9XZ58
CSN5_DROME
JAB1 homolog
Sophophora
<M><D><S><D><A><A><Q><K><T><W><E><L><E><N><N><I><Q><T><L><P><S><C><D><E><I><F><R><Y><D><A><E><Q><Q><R><Q><I><I><D><A><K><P><W><E><K><D><P><H><F><F><K><D><I><K><I><S><A><L><A><L><L><K><M><V><M><H><A><R><S><G><G><T><L><E><V><M><G><L><M><L><G><K><V><E><D><N><T><M><I><V><M><D><A><F><A><L><P><V><E><G><T><E><T><R><V><N><A><Q...
Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to ...
Q9XZ58
P61984
CBID_DESVH
Cobalt-precorrin-6A synthase
Desulfovibrio
<M><E><S><R><A><D><H><A><V><P><A><D><E><G><H><G><A><T><E><P><P><R><G><R><D><R><A><A><L><R><E><G><F><T><T><G><T><A><M><T><A><G><A><V><A><A><L><R><H><V><F><G><L><P><F><L><P><V><L><S><V><P><L><P><P><Q><E><G><V><G><V><P><G><R><L><G><V><P><V><A><E><V><L><T><E><G><D><G><A><T><G><V><V><I><K><D><G><G><D><D><P><D><A><T><H><G><A...
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.<BOP>
P61984
Q1QSC8
ATPA_CHRSD
F-ATPase subunit alpha
Chromohalobacter
<M><Q><Q><L><N><P><S><E><I><S><D><I><I><K><Q><R><I><E><K><L><D><V><A><S><E><A><R><N><E><G><T><V><V><S><V><S><D><G><I><V><K><I><H><G><L><A><D><A><M><F><G><E><M><I><E><F><P><G><S><I><F><G><M><V><L><N><L><E><R><D><S><V><G><A><V><V><L><G><D><Y><L><Q><L><E><E><G><M><T><A><Q><C><T><G><R><I><L><E><V><P><V><G><P><E><L><I><G><R...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
Q1QSC8
P48717
RBL_TROMA
Ribulose bisphosphate carboxylase large chain
Tropaeolum
<S><V><G><F><K><A><G><V><K><D><Y><K><L><T><Y><Y><T><P><D><Y><E><T><K><D><T><D><I><L><A><A><F><R><M><S><P><Q><P><G><V><P><A><E><E><A><G><A><A><V><A><A><E><S><S><T><G><T><W><T><T><V><W><T><D><G><L><T><S><L><D><R><Y><K><G><R><C><Y><Q><I><E><P><V><A><G><E><E><N><Q><Y><I><A><Y><V><A><Y><P><L><D><L><F><E><E><G><S><V><T><N><M...
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.<BOP>
P48717
P23407
RK18_CYAPA
50S ribosomal protein L18, cyanelle
Cyanophora
<M><K><L><T><R><K><Q><A><T><Q><R><R><H><R><R><V><R><R><K><V><F><G><T><S><E><R><P><R><L><A><V><F><R><S><H><Q><H><I><Y><A><Q><I><I><D><D><T><Q><H><R><T><L><A><A><S><S><T><L><E><P><S><V><K><N><S><E><L><S><S><T><S><T><C><A><A><S><A><I><V><G><Q><L><I><A><K><K><A><L><E><K><G><I><T><Q><V><V><F><D><R><G><G><K><I><Y><H><G><R><V...
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.<BOP>
P23407
Q31D21
NU1C_PROM9
NDH-A
Prochlorococcus
<M><E><Y><G><L><D><L><E><Y><S><F><N><E><F><F><K><G><F><G><L><S><S><E><I><A><H><I><I><W><L><P><I><P><M><L><L><V><L><V><A><A><V><V><G><V><L><V><T><V><W><L><E><R><K><I><S><A><A><A><Q><Q><R><I><G><P><E><Y><A><G><A><L><G><V><L><Q><P><I><A><D><G><L><K><L><L><V><K><E><D><I><I><P><A><K><A><D><G><I><L><F><T><A><G><P><I><L><V><L...
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus co...
Q31D21
B0U5A0
ATPA_XYLFM
F-ATPase subunit alpha
Xylella
<M><A><T><T><L><N><P><S><E><I><S><E><L><I><K><T><R><I><E><Q><V><K><L><S><A><E><S><R><N><E><G><T><V><T><S><V><S><D><G><I><V><R><I><F><G><L><A><D><A><M><Q><G><E><M><I><E><L><P><N><K><T><Y><A><L><A><L><N><L><E><R><D><S><V><G><A><V><I><L><G><D><Y><K><H><L><R><E><G><D><V><A><K><T><T><G><R><I><L><E><V><P><V><G><K><S><L><L><G...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
B0U5A0
Q5ZJ37
RABEK_CHICK
Rab9 effector protein with kelch motifs
Gallus
<M><G><P><R><V><L><P><L><L><E><P><G><C><R><P><Q><A><G><K><W><Y><R><M><A><P><R><G><E><W><P><R><G><R><V><G><H><G><C><L><F><V><P><G><G><S><G><R><V><L><L><L><G><G><A><D><P><A><G><A><F><A><D><A><H><F><V><E><L><G><A><H><L><W><A><P><A><A><W><S><G><L><R><P><R><Y><E><H><A><T><F><L><S><A><C><R><P><P><R><L><W><V><F><G><G><A><H><R...
Rab9 effector required for endosome to trans-Golgi network (TGN) transport.<BOP>
Q5ZJ37
A0AEN0
RL9_LISW6
50S ribosomal protein L9
Listeria
<M><K><V><I><F><L><K><D><V><K><G><K><G><K><K><G><E><T><K><N><V><A><D><G><Y><A><N><N><F><L><I><K><N><G><Y><A><V><E><A><S><N><A><A><L><S><T><L><S><A><Q><K><K><K><E><D><K><L><A><A><E><E><L><A><E><A><K><A><L><K><E><K><M><E><K><L><T><V><E><L><K><A><K><S><G><E><G><G><R><L><F><G><S><I><T><S><K><Q><I><A><Q><T><L><E><K><T><H><G...
Binds to the 23S rRNA.<BOP>
A0AEN0
B7HZG7
NOC_BACC7
Nucleoid occlusion protein
Bacillus cereus group
<M><K><N><T><F><S><R><L><F><G><F><G><D><K><E><S><E><F><E><L><Q><D><E><S><H><E><E><I><D><K><K><V><Y><E><E><I><Q><E><I><P><I><V><N><I><T><P><N><R><Y><Q><P><R><T><V><F><D><D><A><R><I><E><E><L><A><L><T><I><R><T><H><G><L><I><Q><P><I><V><V><R><Q><Y><E><D><E><K><Y><E><I><I><A><G><E><R><R><F><R><A><A><T><K><L><G><W><E><K><V><P...
Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z rin...
B7HZG7
A1TAX0
MURD_MYCVP
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Mycolicibacterium
<M><Q><P><I><S><P><G><A><A><V><L><V><V><G><A><G><I><T><G><R><A><V><L><A><A><L><A><P><L><G><A><R><A><T><L><T><D><D><S><P><T><A><L><T><A><S><A><Q><Q><R><V><E><V><L><D><P><A><T><A><V><D><R><I><A><D><F><D><L><V><V><V><S><P><G><I><P><P><T><A><P><I><P><V><A><A><A><A><A><G><I><P><V><W><G><D><V><E><L><A><W><H><L><D><R><S><G><R...
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).<BOP>
A1TAX0
Q47NB8
WHIA_THEFY
Probable cell division protein WhiA
Thermobifida
<M><A><M><T><G><V><V><K><D><E><L><S><R><L><T><V><L><K><P><C><C><R><K><A><E><V><S><T><I><L><R><F><T><G><G><L><H><L><V><G><G><R><I><V><I><E><S><E><L><D><T><G><V><A><A><R><R><L><R><K><D><I><A><E><V><F><G><H><E><S><E><V><L><V><L><S><P><S><G><L><R><K><G><N><R><Y><V><V><R><V><I><K><E><G><E><S><L><A><R><Q><T><G><L><I><D><S><N...
Involved in cell division and chromosome segregation.<BOP>
Q47NB8
Q7IS11
MATK_TAXCU
Intron maturase
Taxus
<M><D><E><F><Q><R><Y><G><N><K><H><K><S><W><Q><Q><C><F><L><Y><P><L><F><F><R><E><D><L><Y><T><I><A><H><D><L><Y><L><D><K><S><S><S><S><E><P><T><E><L><S><I><S><N><F><F><S><F><P><T><V><K><R><L><I><R><R><I><R><Q><Q><N><D><S><N><S><I><G><L><F><R><N><C><D><P><N><R><F><I><N><R><N><R><N><S><Y><S><E><L><V><L><E><G><L><T><V><I><L><E...
Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns.<BOP>
Q7IS11
Q96N22
ZN681_HUMAN
Zinc finger protein 681
Homo
<M><E><P><L><K><F><R><D><V><A><I><E><F><S><L><E><E><W><Q><C><L><D><T><I><Q><Q><N><L><Y><R><N><V><M><L><E><N><Y><R><N><L><V><F><L><G><I><V><V><S><K><P><D><L><I><T><C><L><E><Q><E><K><E><P><W><T><R><K><R><H><R><M><V><A><E><P><P><V><I><C><S><H><F><A><Q><D><F><S><P><E><Q><N><I><K><D><S><F><Q><K><V><T><P><R><R><Y><G><K><C><E...
May be involved in transcriptional regulation.<BOP>
Q96N22
C0M7E5
CODY_STRE4
GTP-sensing transcriptional pleiotropic repressor CodY
Streptococcus
<M><P><N><L><L><E><K><T><R><K><I><T><S><I><L><Q><R><S><V><D><S><L><E><T><E><L><P><Y><N><T><M><A><S><R><L><A><D><I><I><D><C><N><A><C><I><I><N><G><G><G><S><L><L><G><Y><A><M><K><Y><K><T><N><T><D><R><V><E><E><F><F><E><T><R><Q><F><P><D><A><Y><V><K><A><A><S><R><V><Y><D><T><E><A><N><L><S><V><E><N><E><L><T><I><F><P><I><E><S><K...
DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer b...
C0M7E5
A7FJT1
MATP_YERP3
Macrodomain Ter protein
Yersinia
<M><K><Y><Q><Q><L><E><N><L><E><S><G><W><K><W><A><Y><L><V><K><K><H><R><E><G><E><A><I><T><R><H><I><E><N><S><A><A><Q><D><A><V><E><Q><L><M><K><L><E><N><E><P><V><K><V><Q><E><W><I><D><A><H><M><N><V><N><L><A><T><R><M><K><Q><T><I><R><A><R><R><K><R><H><F><N><A><E><H><Q><H><T><R><K><K><S><I><D><L><E><F><L><V><W><Q><R><L><A><V><L...
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.<BOP>
A7FJT1
P50680
COX2_GAZSP
Cytochrome c oxidase polypeptide II
Gazella
<M><A><Y><P><M><Q><L><G><F><Q><D><A><T><S><P><I><M><E><E><L><L><H><F><H><D><H><T><L><M><I><V><F><L><I><S><S><L><V><L><Y><V><I><S><L><M><L><T><T><K><L><T><H><T><S><T><M><D><A><Q><E><V><E><T><I><W><T><I><L><P><A><I><I><L><I><L><I><A><L><P><S><L><R><I><L><Y><M><M><D><E><I><N><N><P><S><L><T><V><K><T><M><G><H><Q><W><Y><W><S...
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII...
P50680
Q5PF04
NRDI_SALPA
Protein NrdI
Salmonella
<M><S><A><L><V><Y><F><S><S><S><S><E><N><T><H><R><F><M><Q><R><L><G><L><P><A><T><R><I><P><L><N><E><R><E><R><I><R><V><D><E><P><Y><I><L><V><V><P><S><Y><G><G><G><G><M><A><G><A><V><P><R><Q><V><I><R><F><L><N><D><E><H><N><R><A><R><I><R><G><V><I><A><S><G><N><R><N><F><G><D><A><W><G><C><A><G><D><V><I><A><Q><K><Y><G><V><P><W><L><Y...
Probably involved in ribonucleotide reductase function.<BOP>
Q5PF04
Q49V08
GLMU_STAS1
Glucosamine-1-phosphate N-acetyltransferase
Staphylococcus
<M><Q><R><H><A><I><V><L><A><A><G><K><G><T><R><M><K><S><K><K><Y><K><V><L><H><D><V><A><G><K><T><M><I><E><H><V><A><D><N><V><K><Q><S><G><I><D><Q><L><V><T><I><V><G><H><G><A><D><S><V><K><E><T><L><G><D><T><S><L><Y><S><F><Q><E><E><Q><L><G><T><A><H><A><V><K><M><A><S><E><H><L><S><E><S><Q><G><T><T><L><V><V><C><G><D><T><P><L><I><T...
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted ...
Q49V08
Q9L6B6
ATPG_PASMU
F-ATPase gamma subunit
Pasteurella
<M><A><G><A><K><E><I><R><T><K><I><A><S><V><K><S><T><Q><K><I><T><K><A><M><E><M><V><A><A><S><K><M><R><K><T><Q><E><R><M><S><S><S><R><P><Y><S><E><T><I><R><N><V><I><S><H><V><S><K><A><T><I><G><Y><K><H><P><F><L><V><D><R><E><V><K><K><V><G><M><I><V><V><S><T><D><R><G><L><C><G><G><L><N><V><N><L><F><K><T><V><L><N><E><M><K><E><W><K...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP>
Q9L6B6
Q8ESM5
PHNC1_OCEIH
Phosphonates import ATP-binding protein PhnC 1
Oceanobacillus
<M><I><E><F><K><D><V><G><L><V><Y><P><N><G><T><E><G><L><K><N><I><N><V><K><I><N><D><G><E><F><V><V><I><V><G><L><S><G><A><G><K><S><T><F><I><R><S><I><N><R><L><V><T><P><T><T><G><E><L><I><I><D><D><E><N><I><L><N><Y><S><G><N><K><L><R><M><L><R><T><K><T><G><M><I><F><Q><N><Y><N><L><V><K><R><S><N><V><F><K><N><V><L><A><G><R><L><G><H...
Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.<BOP>
Q8ESM5
B5YG20
RL20_THEYD
50S ribosomal protein L20
Thermodesulfovibrio
<M><P><R><A><K><G><G><F><K><T><R><R><Y><H><K><K><I><L><S><M><A><K><G><Y><Y><S><G><R><R><R><C><Y><K><V><A><A><K><A><V><E><K><A><L><E><H><S><Y><R><D><R><R><L><K><K><R><D><L><R><S><L><W><I><T><R><I><N><A><A><V><R><M><F><G><L><T><Y><N><Q><F><I><D><G><L><K><K><A><N><I><S><L><N><R><K><A><L><A><D><I><A><Y><N><D><I><N><V><F><G...
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.<BOP>
B5YG20
A8W3B5
RPOC1_CUSEX
Plastid-encoded RNA polymerase subunit beta'
Cuscuta subgen. Monogynella
<M><N><N><N><F><S><S><M><I><D><R><Y><K><H><Q><Q><L><Q><I><G><S><V><S><P><Q><Q><I><S><A><W><A><T><K><I><L><P><N><G><E><I><V><G><E><V><K><K><P><Y><T><F><L><Y><K><T><N><K><P><E><K><E><G><L><F><C><E><R><I><F><G><P><I><K><S><G><I><C><A><C><G><N><Y><R><V><I><G><D><E><K><E><E><Q><K><F><C><E><Q><C><G><V><E><F><V><D><S><R><I><R...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
A8W3B5
B9DY87
ISPD_CLOK1
MEP cytidylyltransferase
Clostridium
<M><K><S><N><Y><A><V><I><V><A><A><G><K><G><K><R><M><K><M><P><I><N><K><Q><F><I><C><I><Q><G><K><P><I><L><Y><Y><S><I><S><V><F><S><K><N><P><L><V><D><K><I><V><L><V><C><A><E><D><E><I><E><Y><C><K><Q><E><I><V><K><K><Y><N><F><D><K><V><V><K><I><V><S><G><G><K><E><R><Q><H><S><V><F><N><A><L><K><V><L><E><N><C><S><V><V><L><I><H><D><G...
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
B9DY87
A8GWP2
SYE1_RICB8
Glutamyl-tRNA synthetase 1
belli group
<M><T><K><V><I><T><R><F><A><P><S><P><T><G><M><L><H><V><G><N><I><R><A><A><L><L><N><W><L><Y><A><K><K><H><D><G><Q><F><I><L><R><F><D><D><T><D><L><E><R><S><K><Q><E><Y><K><D><A><I><R><A><D><L><K><F><L><N><L><N><W><D><Q><T><F><N><Q><L><S><R><L><S><R><Y><D><E><I><K><K><L><L><L><D><K><K><R><L><Y><A><C><Y><E><T><P><E><E><L><E><L...
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP>
A8GWP2
Q47G67
NIFH_DECAR
Nitrogenase reductase
Dechloromonas
<M><A><K><L><R><Q><C><A><I><Y><G><K><G><G><I><G><K><S><T><T><T><Q><N><L><V><A><A><L><A><E><S><G><K><K><V><M><I><V><G><C><D><P><K><A><D><S><T><R><L><I><L><H><S><K><A><Q><T><T><V><M><H><L><A><A><E><A><G><S><V><E><D><L><E><L><E><D><V><L><S><V><G><F><G><G><I><K><C><V><E><S><G><G><P><E><P><G><V><G><C><A><G><R><G><V><I><T><A...
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.<BOP>
Q47G67
P63290
VIP_CAPHI
Vasoactive intestinal polypeptide
Capra
<H><S><D><A><V><F><T><D><N><Y><T><R><L><R><K><Q><M><A><V><K><K><Y><L><N><S><I><L><N>
VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.<BOP>
P63290
B4IAD1
NUBP2_DROSE
Cytosolic Fe-S cluster assembly factor NUBP2 homolog
Sophophora
<M><L><D><K><V><K><N><V><I><V><V><L><S><G><K><G><G><V><G><K><S><T><V><S><T><Q><L><S><L><A><L><R><K><N><G><F><K><V><G><L><L><D><I><D><L><C><G><P><S><V><P><Y><L><L><G><L><E><G><R><D><I><F><Q><C><D><E><G><W><V><P><V><Y><T><D><E><S><Q><T><L><A><V><M><S><I><G><F><L><L><K><N><R><E><D><P><V><I><W><R><G><P><K><K><T><M><M><I><R...
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.<BOP>
B4IAD1
Q9ZD44
RS15_RICPR
30S ribosomal protein S15
typhus group
<M><S><I><T><T><E><R><K><Q><Q><L><I><K><E><Y><A><I><T><E><N><D><T><G><S><T><A><V><Q><C><A><I><L><T><E><R><I><N><N><L><T><E><H><F><K><S><N><H><K><D><H><T><S><R><R><G><L><L><I><L><V><G><R><R><R><R><L><L><N><Y><I><K><K><N><N><V><S><E><Y><L><D><L><I><S><K><L><G><I><R><K><I><K>
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.<BOP>
Q9ZD44
Q5KVY7
YIDD_GEOKA
Putative membrane protein insertion efficiency factor
Geobacillus thermoleovorans group
<M><G><Q><W><L><I><W><C><I><R><F><Y><Q><R><F><L><S><P><L><K><P><P><T><C><R><F><Y><P><T><C><S><N><Y><G><I><E><A><I><R><R><F><G><A><I><K><G><G><W><L><T><A><K><R><I><L><K><C><H><P><F><H><P><G><G><F><D><P><V><P><E><S><S><E><H><A><K><R><N><K><I><T>
Could be involved in insertion of integral membrane proteins into the membrane.<BOP>
Q5KVY7
Q5E8M6
COABC_ALIF1
Phosphopantothenoylcysteine synthetase
Aliivibrio
<M><A><S><L><A><G><K><R><I><L><L><G><I><S><G><G><I><A><A><Y><K><C><A><E><L><T><R><R><L><I><E><R><G><A><E><V><R><V><V><M><T><K><A><A><K><E><F><I><T><P><L><T><M><Q><A><V><S><G><H><P><V><A><D><S><L><L><D><P><A><A><E><A><S><M><G><H><I><E><L><A><K><W><A><D><I><V><L><L><A><P><A><T><A><D><L><I><A><R><M><A><A><G><M><G><N><D><L...
Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.<BOP>
Q5E8M6
Q2JQN1
RL24_SYNJA
50S ribosomal protein L24
unclassified Synechococcus
<M><V><R><P><L><K><P><S><Q><I><R><R><L><I><R><Q><T><G><V><R><K><H><R><N><S><L><R><Y><K><M><R><I><K><K><G><D><T><V><Q><V><I><S><G><D><D><K><G><K><I><G><E><V><L><Q><V><F><P><E><R><N><M><V><L><V><E><G><V><N><I><V><T><Y><H><R><K><P><Q><R><E><G><E><S><G><R><I><E><T><K><E><A><P><I><H><A><C><K><V><M><L><Y><S><K><K><Q><E><V><A...
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.<BOP>
Q2JQN1
A0QVQ3
RS15_MYCS2
30S ribosomal protein S15
Mycolicibacterium
<M><A><L><T><A><E><Q><K><K><E><I><L><G><Q><Y><G><L><H><D><T><D><T><G><S><P><E><A><Q><V><A><L><L><T><K><R><I><Q><D><L><T><E><H><L><K><V><H><K><H><D><H><H><S><R><R><G><L><L><L><L><V><G><R><R><R><R><L><L><K><Y><V><A><Q><V><D><V><A><R><Y><R><S><L><I><E><R><L><G><L><R><R>
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.<BOP>
A0QVQ3
Q89J89
RL22_BRADU
50S ribosomal protein L22
Bradyrhizobium
<M><S><K><P><K><R><E><R><S><L><A><E><N><E><A><K><A><V><A><R><M><L><R><V><S><P><Q><K><L><N><L><V><A><Q><L><I><R><G><R><K><A><A><A><A><L><A><D><L><Q><F><S><R><K><R><I><A><V><D><V><K><K><C><L><E><S><A><I><A><N><A><E><N><N><H><D><L><D><V><D><D><L><V><V><A><Q><A><F><V><G><N><G><L><V><M><K><R><F><A><A><R><G><R><G><R><S><G><R...
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.<BOP>
Q89J89
B2A1G4
HEM1_NATTJ
Glutamyl-tRNA reductase
Natranaerobius
<M><I><L><A><V><I><G><I><N><H><E><T><A><S><V><E><T><R><E><Q><L><A><F><S><S><K><Q><V><K><E><L><V><Q><K><L><I><E><G><Q><P><I><K><E><A><S><V><L><S><T><C><N><R><T><E><V><H><F><T><V><N><T><G><Q><I><E><A><G><K><N><H><I><M><T><Y><L><S><D><F><S><D><L><D><P><R><E><Y><V><D><H><L><Y><F><I><T><D><Q><E><A><V><S><H><I><F><K><V><T><A...
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).<BOP>
B2A1G4
Q861W5
TNFL6_FELCA
SPPL2A-processed FasL form
Felis
<M><Q><Q><P><L><N><Y><P><Y><P><Q><I><Y><W><V><D><S><R><A><S><S><P><W><G><P><P><G><S><V><L><P><C><P><S><S><V><P><G><R><P><G><Q><R><R><P><P><P><P><P><P><P><T><L><P><P><P><P><P><P><P><P><L><P><P><L><P><L><P><P><L><K><T><R><R><D><H><N><T><G><L><C><L><L><V><M><F><F><M><V><L><V><A><L><V><G><L><G><L><G><M><F><Q><L><F><H><L><Q...
Cytoplasmic form induces gene transcription inhibition.<BOP>
Q861W5
P0DTY2
O1620_CONCL
O1_cal6.20
Californiconus
<M><K><L><T><C><V><L><I><V><A><V><L><I><L><T><A><C><Q><V><I><A><A><D><G><W><F><G><E><E><S><S><C><W><W><C><T><G><Q><N><K><C><C><E><E><A><Q><V><C><Q><S><V><N><Y><A><C><P><P><A><R><R>
Probable neurotoxin.<BOP>
P0DTY2
B1ZES7
TRMFO_METPB
Folate-dependent tRNA(M-5-U54)-methyltransferase
Methylorubrum
<M><T><N><P><I><H><I><V><G><G><G><L><A><G><S><E><A><A><W><Q><I><A><Q><G><G><R><R><A><V><L><H><E><M><R><P><R><R><G><T><E><A><H><Q><G><E><G><L><A><E><L><V><C><S><N><S><F><R><S><D><D><A><N><G><N><A><V><G><L><L><H><Q><E><M><R><S><L><N><S><L><I><M><R><A><A><D><A><N><Q><V><P><A><G><G><A><L><A><V><D><R><E><G><F><S><Q><A><V><T...
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.<BOP>
B1ZES7
P35168
CGGR_PRIM3
Central glycolytic genes regulator
Priestia
<M><R><S><L><I><E><V><Q><R><K><L><L><P><E><L><L><S><V><M><Q><K><R><Y><Q><I><L><Q><Y><I><R><L><M><Q><P><I><G><R><R><N><L><A><V><S><L><G><L><T><E><R><V><L><R><S><E><V><T><F><L><K><E><Q><D><L><I><D><I><Y><P><S><G><M><T><L><T><N><E><G><E><L><L><L><A><E><L><E><E><V><M><K><E><V><S><G><L><R><L><L><E><T><T><L><K><E><A><F><S><L...
In the absence of glucose, represses the transcription of the gapA operon, which encodes five key glycolytic enzymes.<BOP>
P35168
Q7NBX3
RF1_MYCGA
Peptide chain release factor 1
Mycoplasma
<M><E><Y><N><K><Q><M><Y><E><T><L><V><A><I><R><A><T><A><Q><K><L><N><K><E><L><E><S><L><T><N><D><F><K><R><I><H><A><I><N><K><E><L><K><Q><K><K><Q><L><L><E><V><F><E><L><Y><D><K><L><V><V><S><G><L><E><A><E><K><I><I><N><D><N><A><M><K><E><F><H><E><L><A><I><L><D><L><D><A><A><K><E><Q><I><P><D><L><E><E><K><L><K><V><L><L><L><P><A><D...
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.<BOP>
Q7NBX3
B7LW41
PANB_ESCF3
Ketopantoate hydroxymethyltransferase
Escherichia
<M><K><P><T><T><I><A><S><L><Q><K><C><K><Q><N><K><K><R><F><A><T><I><T><A><Y><D><Y><S><F><A><K><L><F><A><E><E><G><L><N><V><M><L><V><G><D><S><L><G><M><T><V><Q><G><H><D><S><T><L><P><V><T><V><Q><D><I><A><Y><H><T><A><A><V><R><R><G><A><P><N><C><L><L><L><A><D><L><P><F><M><A><Y><S><T><P><E><Q><A><F><E><N><A><A><T><V><M><R><A><G...
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.<BOP>
B7LW41
Q72MV4
COAE_LEPIC
Dephosphocoenzyme A kinase
Leptospira
<M><Q><N><S><D><S><G><K><K><T><F><L><I><G><I><T><G><M><I><G><G><G><K><S><T><A><T><K><I><L><E><E><M><G><C><F><G><I><N><A><D><R><L><A><K><R><Y><T><E><P><D><S><P><I><L><I><E><L><V><E><L><L><G><S><E><I><L><D><E><Q><G><K><P><D><R><K><K><I><S><E><I><V><F><N><N><P><K><K><L><S><R><L><N><Q><L><I><H><P><L><V><R><K><D><F><Q><K><I...
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.<BOP>
Q72MV4
B1XZN7
ACP_LEPCP
Acyl carrier protein
Leptothrix
<M><S><D><I><E><A><R><V><K><K><I><I><A><E><Q><L><G><V><A><E><A><E><V><T><S><E><K><A><F><V><A><D><L><G><A><D><S><L><D><T><V><E><L><V><M><A><L><E><D><E><F><G><I><E><I><P><D><E><E><A><E><K><I><T><T><V><Q><L><A><I><D><Y><A><K><N><N><V><K><A>
Carrier of the growing fatty acid chain in fatty acid biosynthesis.<BOP>
B1XZN7
O35367
KERA_MOUSE
Keratan sulfate proteoglycan keratocan
Mus
<M><A><T><P><N><C><L><I><L><W><V><L><L><I><A><D><T><V><W><T><Q><S><V><R><Q><A><Y><E><I><Q><D><P><E><D><W><D><V><H><D><D><F><Y><C><P><R><E><C><F><C><P><P><S><F><P><T><A><L><Y><C><E><N><R><G><L><T><E><I><P><P><I><P><S><R><I><W><Y><L><Y><L><E><N><N><L><I><E><S><I><P><E><K><P><F><E><N><A><T><Q><L><R><W><I><N><L><N><K><N><K...
May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.<BOP>
O35367
A1U7I4
RSMG_MARN8
16S rRNA 7-methylguanosine methyltransferase
Marinobacter
<M><S><Y><P><Q><W><P><G><Q><L><R><D><G><L><A><A><M><N><L><S><L><S><D><S><Q><Q><Q><Q><L><L><A><F><L><A><L><L><N><K><W><N><K><A><Y><N><L><T><A><V><R><D><E><R><V><M><V><S><R><Q><L><L><D><S><L><S><I><L><P><W><V><T><T><D><H><L><L><D><V><G><A><G><G><G><L><P><G><I><P><L><A><I><V><V><P><E><K><R><F><T><L><L><D><S><N><G><K><K><T...
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.<BOP>
A1U7I4
Q9P7R4
UBC8_SCHPO
Ubiquitin-protein ligase 8
Schizosaccharomyces
<M><S><S><P><R><R><R><I><E><T><D><V><M><K><L><L><M><S><D><Y><E><V><T><L><V><N><D><N><M><Q><E><F><Y><V><R><F><H><G><P><S><E><T><P><Y><S><G><G><I><W><K><V><H><V><E><L><P><S><E><Y><P><W><K><S><P><S><I><G><F><V><N><R><I><F><H><P><N><I><D><E><L><S><G><S><V><C><L><D><V><I><N><Q><T><W><S><P><M><F><D><M><I><N><I><F><E><V><F><L...
Catalyzes the covalent attachment of ubiquitin to other proteins.<BOP>
Q9P7R4
O69600
ALF_MYCLE
Fructose-1,6-bisphosphate aldolase
Mycobacterium
<M><P><I><A><T><P><E><I><Y><A><E><M><L><R><R><A><K><E><N><S><Y><A><F><P><A><I><N><C><T><S><S><E><T><V><N><A><A><I><K><G><F><A><D><A><G><S><D><G><I><I><Q><F><S><T><G><G><A><E><F><A><S><G><L><G><V><K><D><M><V><T><G><A><V><A><L><A><K><F><T><H><T><I><A><A><K><Y><P><I><N><V><A><L><H><T><D><H><C><P><K><D><K><L><D><S><Y><V><R...
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.<BOP>
O69600
Q5IZM4
CP51_MYCVP
Sterol 14-alpha demethylase
Mycolicibacterium
<M><T><A><V><K><E><V><P><R><V><S><G><G><E><E><E><H><G><H><L><E><E><F><R><T><D><P><I><G><L><M><K><R><V><R><E><E><C><G><D><V><G><W><F><Q><L><A><D><K><Q><V><I><L><L><S><G><A><E><A><N><E><F><F><F><R><S><S><D><S><E><L><N><Q><A><E><A><Y><P><F><M><T><P><I><F><G><E><G><V><V><F><D><A><D><P><E><R><R><A><E><M><L><H><N><T><A><L><R...
Its precise biological substrate is not known. Catalyzes C14-demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.<BOP>
Q5IZM4
Q54ER6
MTND_DICDI
Acireductone dioxygenase (Ni(2+)-requiring)
Dictyostelium
<M><K><S><Y><F><Y><D><N><E><S><D><V><I><S><L><D><Y><L><K><E><H><N><V><L><Y><F><P><M><D><R><E><K><E><N><Y><K><E><P><L><E><T><L><C><K><E><R><G><Y><K><N><R><D><E><V><K><L><S><K><E><T><P><G><L><E><D><K><L><K><I><F><F><E><E><H><L><H><D><D><E><E><I><R><F><I><L><D><G><C><G><F><F><D><I><R><D><K><N><D><K><W><V><K><I><K><E><K><K...
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine...
Q54ER6
Q14166
TTL12_HUMAN
Inactive tubulin--tyrosine ligase-like protein 12
Homo
<M><E><A><E><R><G><P><E><R><R><P><A><E><R><S><S><P><G><Q><T><P><E><E><G><A><Q><A><L><A><E><F><A><A><L><H><G><P><A><L><R><A><S><G><V><P><E><R><Y><W><G><R><L><L><H><K><L><E><H><E><V><F><D><A><G><E><V><F><G><I><M><Q><V><E><E><V><E><E><E><E><D><E><A><A><R><E><V><R><K><Q><Q><P><N><P><G><N><E><L><C><Y><K><V><I><V><T><R><E><S...
Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues . Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3) . Probably by controlling tubulin and/or histone H4 post-translational modifications, play...
Q14166
A9M1A2
GPMA_NEIM0
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Neisseria
<M><E><L><V><F><I><R><H><G><Q><S><E><W><N><A><K><N><L><F><T><G><W><R><D><V><K><L><S><E><Q><G><L><A><E><A><A><A><A><G><K><K><L><K><E><N><G><Y><E><F><D><I><A><F><T><S><V><L><T><R><A><I><K><T><C><N><I><V><L><E><E><S><D><Q><L><F><V><P><Q><I><K><T><W><R><L><N><E><R><H><Y><G><Q><L><Q><G><L><D><K><K><Q><T><A><E><K><Y><G><D><E...
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.<BOP>
A9M1A2
Q2RGY0
DNLJ_MOOTA
Polydeoxyribonucleotide synthase [NAD(+)]
Moorella
<M><D><L><A><A><A><R><Q><R><V><E><E><L><R><R><L><I><E><E><H><N><Y><R><Y><Y><V><L><D><Q><P><S><I><S><D><R><E><Y><D><A><L><M><Q><E><L><I><A><L><E><E><A><Y><P><E><L><R><T><P><D><S><P><S><Q><R><V><G><G><A><P><R><E><E><F><N><Q><V><R><H><P><Q><V><L><L><S><L><N><D><A><F><N><E><G><D><L><L><E><F><D><R><R><V><R><D><L><A><G><R><P...
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP>
Q2RGY0
Q0RKH4
SSUB2_FRAAA
Aliphatic sulfonates import ATP-binding protein SsuB 2
Frankia
<M><G><A><V><T><V><R><G><L><R><R><A><F><G><S><H><V><V><L><D><Q><L><D><L><T><I><A><E><S><E><F><V><A><L><V><G><R><S><G><G><G><K><T><T><L><L><R><T><L><A><G><L><D><P><V><A><E><G><S><V><E><V><P><A><L><R><S><V><V><F><Q><E><P><R><L><L><P><W><R><R><V><W><Q><N><V><A><L><G><L><P><R><S><R><G><R><D><E><A><T><K><A><L><A><E><V><G><L...
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system.<BOP>
Q0RKH4
Q09158
NIFH_DESMC
Nitrogenase reductase
Desmonostoc
<S><T><R><L><M><L><H><S><K><A><Q><T><S><V><L><Q><L><A><A><E><R><G><A><V><E><D><I><E><L><H><E><V><M><L><T><G><F><R><D><V><R><C><V><E><S><G><G><P><E><P><G><V><G><C><A><G><R><G><I><I><T><A><I><N><F><L><E><E><N><G><A><Y><T><D><V><D><F><V><S><Y><D><V><L><G><D><V><V><C><G><G><F><A><M><P><I><R><E><G><K><A><Q><E><I><Y><I><V><T...
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.<BOP>
Q09158
A6L2M8
GLAB2_PHOV8
Exo-alpha-galactosidase B2
Phocaeicola
<M><K><R><I><I><F><N><F><C><F><V><W><L><A><V><S><A><F><A><G><S><K><V><V><E><M><R><N><Y><G><L><V><P><D><T><H><E><N><L><S><P><K><L><Q><K><A><L><Q><D><I><K><S><Q><V><A><L><G><D><K><V><T><L><L><F><E><S><G><R><Y><D><F><H><P><E><G><A><A><V><R><E><Y><Y><I><S><N><H><D><Q><D><N><P><K><T><V><G><F><P><L><E><D><W><K><G><L><T><V><D...
Alpha-galactosidase. Removes both branched alpha-1,3-linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures.<BOP>
A6L2M8
B8DF98
DCUP_LISMH
Uroporphyrinogen decarboxylase
Listeria
<M><T><K><I><T><N><D><L><F><L><K><A><A><R><K><E><Q><V><D><R><I><P><V><W><Y><M><R><Q><A><G><R><S><Q><P><E><Y><R><K><L><K><E><K><Y><S><L><F><E><I><T><H><Q><P><E><I><C><A><Y><V><T><K><L><P><V><D><Q><Y><G><V><D><A><A><I><L><Y><K><D><I><M><T><P><L><P><G><M><G><V><D><V><E><I><K><S><G><I><G><P><V><I><H><N><P><I><R><T><F><Q><D...
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.<BOP>
B8DF98
A8FHS1
PPAX_BACP2
Pyrophosphatase PpaX
Bacillus
<M><N><E><S><T><I><N><T><V><L><F><D><L><D><G><T><L><I><N><T><N><E><L><I><I><A><S><F><Q><H><T><L><D><H><Y><Y><P><G><Q><Y><S><R><E><E><I><L><H><F><I><G><P><S><L><F><D><T><F><S><A><M><D><P><D><L><T><D><D><M><I><Q><M><Y><R><T><F><N><H><E><Q><H><D><L><L><V><T><E><Y><E><T><V><L><D><T><L><K><V><L><Q><D><R><G><F><K><L><G><I><V...
Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.<BOP>
A8FHS1
A0QDL1
RNZ_MYCA1
tRNase Z
Mycobacterium avium complex (MAC)
<M><I><E><V><T><L><L><G><T><G><S><P><I><P><D><P><N><R><A><G><P><S><T><L><V><R><A><G><G><Q><V><F><L><V><D><C><G><R><G><V><L><Q><R><A><A><A><V><G><V><G><A><A><G><L><S><T><L><L><L><T><H><L><H><S><D><H><V><G><D><L><G><D><V><L><I><T><R><W><V><S><T><F><T><P><D><P><V><P><L><P><I><I><G><P><P><G><T><A><E><L><V><A><A><T><L><N><A...
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.<BOP>
A0QDL1
Q9KR19
ALAE_VIBCH
L-alanine exporter AlaE
Vibrio
<M><K><A><R><G><P><F><C><I><R><H><A><A><A><D><T><F><A><M><V><V><F><C><F><V><T><G><M><I><I><E><I><F><V><S><G><M><T><F><Q><Q><S><L><A><S><R><T><L><S><I><P><V><N><I><A><I><A><W><P><Y><G><V><F><R><D><Y><V><L><R><Q><G><R><K><I><S><P><T><G><W><M><K><N><L><S><D><L><V><A><Y><V><L><F><Q><S><P><V><Y><A><A><I><L><F><T><V><G><A><S...
Exports L-alanine.<BOP>
Q9KR19
Q55075
RADA_SACS2
DNA repair and recombination protein RadA
Saccharolobus
<M><S><N><E><V><E><Q><K><K><N><I><K><T><I><N><D><L><P><G><I><S><Q><T><V><I><N><K><L><I><E><A><G><Y><S><S><L><E><T><L><A><V><A><S><P><Q><D><L><S><V><A><A><G><I><P><L><S><T><A><Q><K><I><I><K><E><A><R><D><A><L><D><I><R><F><K><T><A><L><E><V><K><K><E><R><M><N><V><K><K><I><S><T><G><S><Q><A><L><D><G><L><L><A><G><G><I><E><T><R...
Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.<BOP>
Q55075
A1AWH8
PURA_RUTMC
IMP--aspartate ligase
Candidatus Ruthia
<M><S><K><N><V><V><I><I><G><T><Q><W><G><D><E><G><K><G><K><V><V><D><L><I><T><D><K><V><A><S><V><V><R><F><Q><G><G><H><N><A><G><H><T><L><V><I><N><G><K><T><T><I><L><H><L><I><P><S><G><I><L><R><N><H><V><E><C><L><I><G><H><G><V><V><L><S><M><S><A><L><L><K><E><I><A><E><L><E><V><A><D><I><D><T><T><K><R><L><K><I><S><P><G><C><P><L><I...
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP>
A1AWH8
O75081
MTG16_HUMAN
Zinc finger MYND domain-containing protein 4
Homo
<M><P><A><S><R><L><R><D><R><A><A><S><S><A><S><G><S><T><C><G><S><M><S><Q><T><H><P><V><L><E><S><G><L><L><A><S><A><G><C><S><A><P><R><G><P><R><K><G><G><P><A><P><V><D><R><K><A><K><A><S><A><M><P><D><S><P><A><E><V><K><T><Q><P><R><S><T><P><P><S><M><P><P><P><P><P><A><A><S><Q><G><A><T><R><P><P><S><F><T><P><H><T><H><R><E><D><G><P...
Isoform 2 functions as an A-kinase-anchoring protein .<BOP>
O75081
A0RQI7
RL10_CAMFF
50S ribosomal protein L10
Campylobacter
<M><T><R><N><E><K><A><E><I><I><S><N><L><E><A><E><F><K><T><S><D><A><I><V><V><C><D><Y><K><G><L><S><V><K><K><L><E><A><L><R><N><S><A><R><E><L><N><V><K><V><Q><V><V><K><N><T><L><A><N><I><A><L><N><N><C><G><K><S><G><M><E><L><K><D><T><N><I><F><V><W><G><E><D><Q><L><A><V><T><K><V><V><A><K><F><E><E><S><N><N><E><L><F><K><I><K><T><A...
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.<BOP>
A0RQI7
A5IHB4
TRMB_LEGPC
tRNA(m7G46)-methyltransferase
Legionella
<M><Q><R><K><I><K><S><Y><V><L><R><A><G><R><I><S><N><R><Q><Q><Q><G><L><D><L><W><L><E><D><Y><E><L><K><F><D><S><P><S><P><W><N><F><A><K><E><F><G><R><H><D><A><D><T><I><V><E><I><G><F><G><M><G><T><S><L><F><T><M><A><M><N><N><P><Q><C><N><Y><L><G><I><E><V><H><K><A><G><V><G><S><L><V><A><D><L><H><E><H><Q><I><T><N><V><R><V><V><V><H...
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP>
A5IHB4
Q3KM49
TAL_CHLTA
Transaldolase
Chlamydia
<M><S><S><Q><F><D><Q><L><K><L><W><S><V><L><V><G><D><T><G><D><P><A><L><I><K><T><L><G><V><Q><D><A><T><T><N><P><S><L><I><L><K><V><A><Q><E><P><K><Y><Q><S><M><L><K><E><A><I><S><W><G><I><R><Q><N><G><D><D><V><Q><T><L><T><F><V><L><D><K><I><Q><V><N><L><G><L><E><I><L><K><H><V><P><G><R><V><S><L><E><I><D><A><R><L><S><F><N><T><E><A...
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP>
Q3KM49
P60980
VSTX1_GRARO
Voltage sensor toxin 1
Grammostola
<M><K><T><S><V><F><V><L><V><L><G><L><V><L><L><F><A><V><S><F><A><T><E><M><E><E><S><A><R><E><C><G><K><F><M><W><K><C><K><N><S><N><D><C><C><K><D><L><V><C><S><S><R><W><K><W><C><V><L><A><S><P><F>
Inhibits sodium channels Nav1.7/SCN9A and potassium channels Kv11.1/KCNH2. Also binds the voltage-sensor domain of the potassium channel KvAP (from the archaeon Aeropyrum pernix) with very slow apparent binding kinetics and affects channel gating. Reaches its target by dynamically partitioning into anionic or zwitterio...
P60980
A5CCV6
YQGF_ORITB
Putative pre-16S rRNA nuclease
Orientia
<M><I><I><N><S><I><S><E><F><L><Q><A><A><D><I><K><K><Q><I><L><G><I><D><F><G><E><K><K><V><G><V><A><I><S><N><I><E><H><T><V><A><M><P><L><Q><T><I><L><A><T><N><Q><D><R><V><N><K><I><Q><E><I><A><V><A><Y><N><I><G><A><I><V><I><G><L><P><F><K><L><D><G><T><E><T><S><Q><T><H><R><V><K><D><F><A><N><K><L><A><N><K><L><L><L><P><I><F><L><C...
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP>
A5CCV6
B3DI94
TM186_DANRE
Transmembrane protein 186
Danio
<M><D><M><M><M><M><S><T><R><L><I><H><L><S><R><H><F><P><Q><Y><G><F><R><C><H><P><S><G><L><I><S><S><A><R><M><Q><Y><N><I><N><N><G><L><A><H><M><G><K><Q><M><P><N><T><S><T><H><T><T><R><I><H><P><A><S><F><S><S><D><L><A><S><R><K><Y><S><L><I><Y><A><F><P><L><I><R><G><L><R><A><L><S><R><L><K><L><L><Q><T><G><I><T><V><V><L><L><P><T><V...
May be required for efficient assembly of the mitochondrial complex I.<BOP>
B3DI94
Q5NRF6
YBEY_ZYMMO
Endoribonuclease YbeY
Zymomonas
<M><I><T><V><E><A><D><I><S><D><L><W><P><E><Q><S><N><W><E><A><L><A><Q><T><A><C><Q><Q><A><V><S><V><S><A><S><D><F><L><L><A><K><D><Y><E><T><E><I><S><V><C><F><S><D><N><D><T><V><H><A><L><N><K><T><W><R><D><K><D><R><P><T><N><V><L><S><F><P><M><M><E><A><E><E><L><A><E><I><K><N><R><V><G><S><E><C><L><L><G><D><I><I><L><A><F><D><V><A...
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP>
Q5NRF6
Q12LA0
TIG_SHEDO
PPIase
Shewanella
<M><Q><V><S><V><E><T><T><E><G><L><G><R><R><L><T><I><S><V><P><A><E><Q><I><E><K><M><V><K><D><G><I><T><R><E><A><K><R><A><R><L><P><G><F><R><P><G><K><V><P><L><S><E><I><N><K><R><Y><G><Q><A><I><R><Q><D><V><M><G><E><V><M><Q><R><N><F><I><E><A><I><I><A><E><K><L><N><P><A><G><A><P><T><F><M><P><G><K><S><V><G><E><S><F><E><F><V><A><T...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
Q12LA0
Q110N2
TATA_TRIEI
Sec-independent protein translocase protein TatA
Trichodesmium
<M><N><I><F><G><I><G><L><P><E><M><I><V><I><L><V><V><A><L><L><I><F><G><P><K><K><L><P><E><I><G><R><S><L><G><Q><A><I><N><S><F><K><A><G><A><R><D><F><E><N><E><F><K><R><E><A><K><H><L><E><E><G><V><K><V><S><T><S><A><S><E><P><E><K><V><V><D><V><S><S><A><T><N><T><N><K><N>
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP>
Q110N2
D0KWI6
TATC_HALNC
Sec-independent protein translocase protein TatC
Halothiobacillus
<M><T><E><R><D><S><S><P><E><A><D><K><N><G><L><A><D><V><V><E><E><T><G><M><A><G><F><L><G><H><L><V><E><L><R><N><R><L><L><K><G><V><L><A><V><L><V><L><F><L><I><L><F><P><F><R><N><E><L><F><T><M><L><A><D><P><L><S><R><H><M><P><A><G><S><T><M><I><A><V><E><V><A><S><P><F><F><I><P><L><K><L><T><A><L><T><A><V><F><I><A><I><P><F><L><L><Y...
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.<BOP>
D0KWI6
P11019
VATE1_BOVIN
Vacuolar proton pump subunit E 1
Bos
<M><A><L><S><D><A><D><V><Q><K><Q><I><K><H><M><M><A><F><I><E><Q><E><A><N><E><K><A><E><E><I><D><A><K><A><E><E><E><F><N><I><E><K><G><R><L><V><Q><T><Q><R><L><K><I><M><E><Y><Y><E><K><K><E><K><Q><I><E><Q><Q><K><K><I><Q><M><S><N><L><M><N><Q><A><R><L><K><V><L><R><A><R><D><D><L><I><T><D><L><L><N><E><A><K><Q><R><L><S><K><V><V><K...
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types...
P11019
Q2NW05
TYPH_SODGM
TdRPase
Sodalis
<M><F><L><A><Q><E><I><I><R><K><K><R><D><G><E><P><L><S><D><E><E><I><R><F><F><I><N><G><V><Y><D><N><T><V><S><E><G><Q><I><A><A><L><A><M><T><I><F><F><H><D><M><D><L><Q><E><R><V><A><L><T><L><A><M><R><D><S><G><H><T><L><D><W><R><R><E><A><L><G><G><P><V><V><D><K><H><S><T><G><G><V><G><D><V><T><S><L><M><L><G><P><M><I><A><A><C><G><G...
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.<BOP>
Q2NW05
O94265
THI21_SCHPO
Hydroxymethylpyrimidine phosphate kinase 1
Schizosaccharomyces
<M><I><S><T><C><I><T><V><A><G><S><D><C><S><G><G><A><G><V><Q><A><D><L><K><V><F><T><A><H><S><V><Y><G><M><S><A><V><T><A><I><T><S><Q><N><T><I><G><V><N><G><V><H><L><I><P><A><S><Y><V><E><Q><Q><I><S><A><C><L><L><D><V><H><C><E><V><M><K><T><G><M><L><F><N><Q><Q><I><L><K><V><I><V><E><S><I><D><R><F><K><I><K><K><V><V><V><D><P><L><I...
Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.<BOP>
O94265
O22349
TBA3_ELEIN
Alpha-3-tubulin
Eleusine
<M><R><E><I><I><S><I><H><I><G><Q><A><G><I><Q><V><G><N><A><C><W><E><L><Y><C><L><E><H><G><I><E><P><D><G><T><M><P><S><D><T><S><V><G><V><A><H><D><A><F><N><T><F><F><S><E><T><G><S><G><K><H><V><P><R><A><I><F><V><D><L><E><P><T><V><I><D><E><V><R><T><G><S><Y><R><Q><L><F><H><P><E><Q><L><I><S><G><K><E><D><A><A><N><N><F><A><R><G><H...
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-...
O22349
P93083
TDC2_CAMAC
Tryptophan decarboxylase TDC2
Camptotheca
<M><G><S><I><D><S><N><Y><D><T><E><S><A><G><Q><C><R><P><L><E><P><E><E><F><R><K><Q><A><H><Q><M><V><D><F><I><A><D><Y><Y><K><N><I><E><S><Y><P><V><L><S><Q><V><E><P><G><Y><L><Q><S><R><L><P><E><T><A><P><Y><R><P><E><P><F><E><S><I><L><K><D><V><H><K><D><I><I><P><G><V><T><H><W><L><S><P><N><F><F><A><Y><F><P><A><T><V><S><S><A><A><F...
Involved in the biosynthesis of tryptamine. Supplies tryptamine for the indole moiety of camptothecin (CPT), an anti-cancer monoterpene alkaloid. Represents a key step in monoterpene indole alkaloid biosynthesis. Is specific for tryptophan, and inactive against tyrosine, phenylalanine and 3,4-dihydroxyphenylalanine (do...
P93083
Q9S7B5
THRC1_ARATH
Protein METHIONINE OVER-ACCUMULATOR 2
Arabidopsis
<M><A><S><S><C><L><F><N><A><S><V><S><S><L><N><P><K><Q><D><P><I><R><R><H><R><S><T><S><L><L><R><H><R><P><V><V><I><S><C><T><A><D><G><N><N><I><K><A><P><I><E><T><A><V><K><P><P><H><R><T><E><D><N><I><R><D><E><A><R><R><N><R><S><N><A><V><N><P><F><S><A><K><Y><V><P><F><N><A><A><P><G><S><T><E><S><Y><S><L><D><E><I><V><Y><R><S><R><S...
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.<BOP>
Q9S7B5
A6H2G3
TATA_FLAPJ
Sec-independent protein translocase protein TatA
Flavobacterium
<M><G><R><L><G><V><T><E><I><L><M><I><L><A><V><V><L><L><L><F><G><G><K><K><I><P><E><L><M><K><G><L><G><S><G><L><S><E><F><K><K><A><A><K><G><D><E><V><P><D><S><K><K><D><E><T><K><E>
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP>
A6H2G3
Q2YS22
TYSY_BRUA2
Thymidylate synthase
Brucella
<M><R><T><Y><L><D><L><L><Q><H><V><L><D><H><G><V><D><R><D><D><R><T><G><T><G><T><R><S><V><F><G><Y><Q><M><R><F><D><L><E><E><G><F><P><V><L><T><T><K><K><L><H><L><R><S><I><I><H><E><L><L><W><F><L><K><G><D><T><N><I><A><Y><L><K><E><N><G><V><T><I><W><D><E><W><A><D><E><N><G><D><L><G><P><V><Y><G><Y><Q><W><R><S><W><P><A><P><D><G><R...
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell...
Q2YS22
Q00063
THRC_ASHGO
Threonine synthase
Eremothecium
<M><S><Q><V><Y><R><S><T><R><S><S><S><E><D><T><K><S><F><E><E><A><V><I><Q><G><L><A><E><D><G><G><L><F><L><P><A><V><I><P><R><L><R><E><E><T><L><F><E><H><W><A><H><L><S><F><Q><D><L><A><M><E><I><M><K><F><Y><I><A><D><W><E><I><P><A><P><E><L><R><E><L><I><E><R><S><Y><S><S><F><R><S><E><E><V><T><P><L><R><K><N><V><T><G><D><D><E><N><L...
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.<BOP>
Q00063
Q9VLN1
WDR82_DROME
WD repeat-containing protein 82
Sophophora
<M><K><I><K><L><I><D><S><V><V><R><S><F><K><V><A><K><I><F><R><E><N><T><D><K><I><N><A><I><D><F><A><P><N><G><E><H><L><I><S><C><S><E><D><D><Q><I><V><I><Y><D><C><E><K><G><T><Q><S><R><T><V><N><S><K><K><Y><G><V><D><L><I><H><F><T><H><A><N><N><T><A><I><H><S><S><T><K><V><D><D><T><I><R><Y><L><S><L><H><D><N><K><Y><L><R><Y><F><P><G...
Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 . Together with su(sable), part of a transcription termination checkpoint that promotes transcription termination of aberrant RNAs and their subsequent degradation by the nuclear exosome .<BOP>
Q9VLN1
P70327
TBX6_MOUSE
T-box transcription factor TBX6
Mus
<M><Y><H><P><R><E><L><Y><P><S><L><G><T><G><Y><R><L><G><H><P><Q><P><G><A><D><S><T><F><P><P><A><L><T><E><G><Y><R><Y><P><D><L><D><T><S><K><L><D><C><F><L><S><G><I><E><A><A><P><H><T><L><A><A><A><A><P><L><P><L><L><P><S><A><L><G><P><E><T><A><P><P><P><P><E><A><L><H><S><L><P><G><V><S><L><S><L><E><N><Q><E><L><W><K><E><F><S><A><V...
T-box transcription factor that plays an essential role in the determination of the fate of axial stem cells: neural vs mesodermal. Acts in part by down-regulating, a specific enhancer (N1) of SOX2, to inhibit neural development. Seems to play also an essential role in left/right axis determination and acts through eff...
P70327
P18728
ZG53_XENLA
Gastrula zinc finger protein XlCGF53.1
Xenopus
<M><G><M><W><E><E><A><S><D><T><G><M><K><G><K><K><K><K><K><D><K><N><E><E><E><E><E><E><R><G><K><K><E><R><M><V><N><L><T><L><E><M><I><Y><L><L><T><G><E><H><Y><I><P><R><K><K><S><D><D><G><G><A><L><H><A><P><G><S><V><I><Q><K><E><N><N><K><N><D><E><K><I><L><E><L><M><S><N><I><I><Q><L><L><T><G><E><V><A><I><R><T><H><H><V><S><I><Y><F...
May be involved in transcriptional regulation.<BOP>
P18728
C1CNW3
TRHO_STRZT
tRNA hydroxylation protein O
Streptococcus
<M><A><K><D><I><R><V><L><L><Y><Y><L><Y><T><P><I><E><N><A><E><Q><F><A><A><D><H><L><A><F><C><K><S><I><G><L><K><G><R><I><L><V><A><D><E><G><I><N><G><T><V><S><G><D><Y><E><T><T><Q><K><Y><M><D><Y><V><H><S><L><P><G><M><E><D><L><W><F><K><I><D><E><E><S><E><Q><A><F><K><K><M><F><V><R><Y><K><K><E><I><V><H><L><G><L><E><D><N><D><F><D...
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP>
C1CNW3
Q845X9
TRPD_BURM1
Anthranilate phosphoribosyltransferase
Burkholderia cepacia complex
<M><T><I><T><P><Q><E><A><L><Q><R><T><I><E><H><R><E><I><F><H><D><E><M><L><H><L><M><R><L><I><M><R><G><D><M><S><P><V><M><A><A><A><I><I><T><G><L><R><V><K><K><E><T><I><G><E><I><A><A><A><A><T><V><M><R><E><F><A><N><H><V><E><V><Q><D><N><S><N><F><V><D><I><V><G><T><G><G><D><G><S><H><T><F><N><I><S><T><A><S><M><F><V><T><A><A><A><G...
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP>
Q845X9
B7NVN0
TRPA_ECO7I
Tryptophan synthase alpha chain
Escherichia
<M><E><R><Y><E><S><L><F><I><R><L><K><E><R><H><E><G><A><F><V><P><F><V><T><L><G><D><P><G><I><E><Q><S><L><K><I><I><D><T><L><I><E><A><G><A><D><A><L><E><L><G><I><P><F><S><D><P><L><A><D><G><P><T><I><Q><N><A><T><L><R><A><F><A><A><G><V><T><P><A><Q><C><F><E><M><L><A><L><I><R><Q><K><H><P><T><I><P><I><G><L><L><M><Y><A><N><L><V><F...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
B7NVN0
Q8U094
TRPA_PYRFU
Tryptophan synthase alpha chain
Pyrococcus
<M><F><K><D><G><S><L><I><P><Y><L><T><A><G><D><P><D><K><Q><S><T><L><N><F><L><L><A><L><D><E><Y><A><G><A><I><E><L><G><I><P><F><S><D><P><I><A><D><G><K><T><I><Q><E><S><H><Y><R><A><L><K><N><G><F><K><L><R><E><A><F><W><I><V><K><E><F><R><R><H><S><S><T><P><I><V><L><M><T><Y><Y><N><P><I><Y><R><A><G><V><R><N><F><L><A><E><A><K><A><S...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
Q8U094
Q9SLG3
ZIP3_ARATH
ZRT/IRT-like protein 3
Arabidopsis
<M><K><T><K><N><V><K><L><L><F><F><F><F><S><V><S><L><L><L><I><A><V><V><N><A><A><E><G><H><S><H><G><G><P><K><C><E><C><S><H><E><D><D><H><E><N><K><A><G><A><R><K><Y><K><I><A><A><I><P><T><V><L><I><A><G><I><I><G><V><L><F><P><L><L><G><K><V><F><P><S><L><R><P><E><T><C><F><F><F><V><T><K><A><F><A><A><G><V><I><L><A><T><G><F><M><H><V...
Mediates zinc uptake from the rhizosphere. May also transport other divalent cations.<BOP>
Q9SLG3
B3Q867
TSAD_RHOPT
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Rhodopseudomonas
<M><T><S><E><Q><A><L><L><V><L><G><I><E><T><T><C><D><E><T><A><A><A><V><V><E><R><R><A><D><G><S><G><R><L><L><S><N><I><V><R><S><Q><T><D><E><H><A><P><F><G><G><V><V><P><E><I><A><A><R><A><H><V><D><V><L><D><G><I><I><A><A><A><M><N><E><A><G><V><A><F><A><S><L><S><G><V><A><A><A><A><G><P><G><L><I><G><G><V><I><V><G><L><T><T><A><K><A...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
B3Q867
Q8FHF8
YDEP_ECOL6
Protein YdeP
Escherichia
<M><K><K><K><I><E><S><Y><Q><G><A><A><G><G><W><G><A><V><K><S><V><A><N><A><V><R><K><Q><M><D><I><R><Q><D><V><I><A><M><F><D><M><N><K><P><E><G><F><D><C><P><G><C><A><W><P><D><P><K><H><S><A><S><F><D><I><C><E><N><G><A><K><A><I><A><W><E><V><T><D><K><Q><V><N><A><S><F><F><A><E><N><T><V><Q><S><L><L><T><W><G><D><H><E><L><E><A><A><G...
Probably involved in acid resistance.<BOP>
Q8FHF8
A8H738
TRUB_SHEPA
tRNA-uridine isomerase
Shewanella
<M><A><R><R><S><R><G><R><F><I><D><G><I><V><L><L><D><K><D><T><G><M><S><S><N><F><A><L><Q><R><V><K><R><F><F><N><A><N><K><A><G><H><T><G><A><L><D><P><L><A><T><G><M><L><P><I><C><L><G><E><A><T><K><F><S><Q><H><L><L><D><A><D><K><R><Y><L><V><T><A><K><L><G><Q><R><T><D><T><S><D><S><D><G><E><I><V><Q><T><R><E><V><N><F><T><Q><E><Q><L...
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP>
A8H738
Q9NSU2
TREX1_HUMAN
Deoxyribonuclease III
Homo
<M><G><S><Q><A><L><P><P><G><P><M><Q><T><L><I><F><F><D><M><E><A><T><G><L><P><F><S><Q><P><K><V><T><E><L><C><L><L><A><V><H><R><C><A><L><E><S><P><P><T><S><Q><G><P><P><P><T><V><P><P><P><P><R><V><V><D><K><L><S><L><C><V><A><P><G><K><A><C><S><P><A><A><S><E><I><T><G><L><S><T><A><V><L><A><A><H><G><R><Q><C><F><D><D><N><L><A><N><L...
Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini . Prevents cell-intrinsic initiation of autoimmunity . Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements . Plays a key role in ...
Q9NSU2
A5II09
TRHO_LEGPC
tRNA hydroxylation protein O
Legionella
<M><K><D><I><I><I><A><S><F><Y><K><F><I><P><L><N><D><F><E><S><L><R><E><P><I><L><T><K><M><H><E><I><G><I><K><G><T><I><I><L><A><H><E><G><V><N><G><G><F><A><G><N><R><E><Q><M><N><V><F><Y><D><Y><L><R><S><D><S><R><F><A><D><L><H><F><K><E><T><Y><D><S><K><N><P><F><D><K><A><K><V><K><L><R><K><E><I><V><T><M><G><V><Q><K><V><D><P><S><Y...
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP>
A5II09
Q21BZ6
UBIG_RHOPB
3-demethylubiquinone 3-O-methyltransferase
Rhodopseudomonas
<M><S><M><Q><S><N><S><S><D><A><S><S><A><T><V><D><P><A><E><I><A><K><F><S><R><L><S><A><Q><W><W><D><P><T><G><K><M><A><P><L><H><K><I><N><P><L><R><L><S><F><I><R><D><A><A><C><R><K><F><E><R><N><A><K><S><L><N><C><L><S><G><L><R><M><I><D><I><G><C><G><A><G><L><L><C><E><P><F><T><R><L><G><A><Q><V><I><G><V><D><P><S><A><T><N><I><A><A...
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP>
Q21BZ6