accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P31292 | WNT10_XENLA | Protein Wnt-10 | Xenopus | <Q><E><C><K><C><H><G><T><S><G><S><C><Q><F><K><T><C><W><Y><V><T><P><D><F><R><A><V><S><T><L><M><R><D><K><L><Q><R><A><V><F><V><N><S><R><N><K><N><S><G><A><F><H><P><R><L><N><K><K><R><L><Q><R><E><L><V><Y><F><E><K><S><P><D><F><C><E><K><D><P><R><V><D><S><L><G><T><Q><G><R><V><C><N><K><T><S><Q><Q><M><D><N><C><A><S><L><C><C><G><R... | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.<BOP> | P31292 |
B1J1Y7 | THIE_PSEPW | Thiamine-phosphate pyrophosphorylase | Pseudomonas | <M><K><L><R><G><L><Y><A><I><T><D><S><Q><L><L><A><G><R><F><L><T><H><V><E><A><A><L><E><G><G><V><R><L><L><Q><Y><R><D><K><S><D><D><A><A><R><R><L><R><E><A><Q><A><L><Q><K><L><C><E><R><Y><G><T><E><L><V><I><N><D><D><A><E><L><A><A><R><L><G><V><G><V><H><L><G><Q><T><D><G><P><L><T><P><A><R><A><L><L><G><R><Q><A><I><I><G><S><T><C><H... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | B1J1Y7 |
Q9HXY2 | UPPS_PSEAE | Undecaprenyl pyrophosphate synthase | Pseudomonas | <M><E><K><T><R><K><D><V><C><V><P><R><H><V><A><I><I><M><D><G><N><N><R><W><A><K><K><R><L><L><P><G><V><A><G><H><K><A><G><V><D><A><V><R><A><V><I><E><V><C><A><E><A><G><V><E><V><L><T><L><F><A><F><S><S><E><N><W><Q><R><P><A><D><E><V><S><A><L><M><E><L><F><L><V><A><L><R><R><E><V><R><K><L><D><E><N><G><I><R><L><R><I><I><G><D><R><T... | Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide c... | Q9HXY2 |
Q9I2Q0 | TSI1_PSEAE | Immune protein Tsi1 | Pseudomonas | <M><K><L><L><A><G><S><F><A><A><L><F><L><S><L><S><A><Q><A><A><D><C><T><F><T><Q><L><E><I><V><P><Q><F><G><S><P><N><M><F><G><G><E><D><E><H><V><R><V><M><F><S><N><E><D><P><N><D><D><N><P><D><A><F><P><E><P><P><V><Y><L><A><D><R><D><S><G><N><D><C><R><I><E><D><G><G><I><W><S><R><G><G><V><F><L><S><Q><D><G><R><R><V><L><M><H><E><F><S... | Immunity protein that plays a role in preventing early activation of toxin Tse1. Binds to a large surface of Tse1 and thereby occludes the active site to specifically inhibits enzyme activity by forming a hydrogen bond with the catalytic diad.<BOP> | Q9I2Q0 |
A6MFL2 | VKT2_DEMVE | Kunitz-type serine protease inhibitor vestiginin-2 | Demansia | <M><S><S><G><G><L><L><L><L><L><G><L><L><T><L><W><A><E><L><T><P><V><S><S><K><D><R><P><E><F><C><E><L><P><P><D><R><G><T><C><M><G><Y><S><Q><A><F><Y><Y><N><P><S><Q><N><K><C><L><P><F><M><F><G><G><C><K><A><N><P><N><N><F><K><T><L><E><E><C><K><R><T><C><A><A> | Serine protease inhibitor.<BOP> | A6MFL2 |
A3CLI1 | TRHO_STRSV | tRNA hydroxylation protein O | Streptococcus | <M><A><K><D><I><R><V><L><L><Y><Y><K><Y><V><P><I><E><N><A><E><K><F><A><A><D><H><L><A><F><C><K><S><I><G><L><K><G><R><I><L><V><A><D><E><G><I><N><G><T><V><S><G><D><Y><E><T><T><Q><K><Y><M><D><Y><V><H><S><L><P><G><M><E><D><L><W><F><K><I><D><E><E><N><E><Q><A><F><K><K><M><F><V><R><Y><K><K><E><I><V><H><L><G><L><E><D><N><D><F><D... | Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP> | A3CLI1 |
Q12667 | XYNA_PIRSP | Xylanase A | unclassified Piromyces | <M><K><L><F><Q><I><F><P><L><L><L><S><L><T><S><V><T><L><A><A><D><D><F><C><N><A><T><G><F><Q><G><Q><S><V><V><S><T><G><H><D><V><K><K><I><G><N><I><D><Y><E><Q><W><A><D><G><G><N><N><S><A><T><F><Y><S><D><G><S><F><K><C><N><F><S><N><T><K><D><Y><L><C><R><S><G><V><A><F><S><Q><A><K><Y><P><S><E><I><G><H><I><E><A><E><Y><R><L><V><K><K... | Hydrolyzes 1,4-beta linked polysaccharide backbones of xylans, one of the major hemicellulose components in hardwoods and softwoods. It is more active against xylopentaose than xylotetraose, has trace activity against xylotriose. The major products released from hydrolysis of xylooligosaccharides are xylobiose and xylo... | Q12667 |
Q9YGJ2 | VSP1_GLOHA | Snake venom serine protease pallabin | Gloydius | <M><V><L><I><R><V><L><A><N><L><L><I><L><Q><L><S><Y><A><Q><K><S><S><K><L><V><I><G><G><D><E><C><N><I><N><E><H><R><F><L><V><A><L><Y><T><S><R><T><L><F><C><G><G><T><L><I><N><Q><E><W><V><L><T><A><A><H><C><N><M><E><D><I><Q><I><K><L><G><M><H><S><K><K><V><P><N><E><D><E><Q><K><R><V><P><K><E><K><F><F><C><L><S><S><K><N><Y><T><L><W... | Snake venom serine protease that may act in the hemostasis system of the prey.<BOP> | Q9YGJ2 |
A4F9T1 | YBEY_SACEN | Endoribonuclease YbeY | Saccharopolyspora | <M><S><I><E><I><A><N><E><S><G><V><E><V><P><E><P><S><I><V><S><V><A><R><F><A><L><D><K><M><S><V><S><Q><L><A><E><L><S><I><V><L><V><E><L><D><V><M><S><D><L><H><E><R><W><M><D><L><P><G><P><T><D><V><M><A><F><P><M><D><E><Y><D><S><S><R><R><P><D><S><A><G><A><G><P><A><L><L><G><D><I><V><L><C><P><A><F><A><K><D><Q><A><R><K><A><G><H><S... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | A4F9T1 |
A9N0K2 | THIG_SALPB | Thiazole synthase | Salmonella | <M><L><R><I><A><D><K><T><F><D><S><H><L><F><T><G><T><G><K><F><A><S><S><Q><L><M><V><E><A><I><R><A><S><G><S><Q><L><V><T><L><A><M><K><R><V><D><L><R><Q><H><N><D><A><I><L><A><P><L><I><E><A><G><V><T><L><L><P><N><T><S><G><A><K><T><A><E><E><A><I><F><A><A><Q><L><A><R><E><A><L><G><T><N><W><L><K><L><E><I><H><P><D><A><R><W><L><L><P... | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP> | A9N0K2 |
Q6IVA4 | UBA5_CHICK | Ubiquitin activating enzyme-like protein | Gallus | <M><A><E><R><V><E><L><L><E><R><R><V><R><E><L><E><R><E><L><E><L><A><R><G><G><R><A><S><A><R><A><R><I><E><T><M><S><P><E><V><T><D><S><N><P><Y><S><R><L><M><A><L><K><R><M><G><I><V><K><D><Y><E><K><I><R><T><F><T><V><A><I><V><G><V><G><G><V><G><S><V><T><A><E><M><L><T><R><C><G><I><G><K><L><L><L><F><D><Y><D><K><V><E><L><A><N><M><N... | E1-like enzyme which specifically catalyzes the first step in ufmylation. Activates UFM1 by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a UFM1-E1 thioester and free AMP. Activates UFM1 via a trans-binding mechanis... | Q6IVA4 |
Q9D709 | TMM79_MOUSE | Mattrin | Mus | <M><T><E><P><E><T><L><A><L><L><D><M><K><E><P><E><T><P><E><K><S><P><P><Q><A><L><V><L><Q><S><E><E><E><G><G><T><E><S><P><G><T><E><S><L><R><V><G><S><S><V><G><S><P><I><V><R><E><G><P><E><D><G><P><D><S><T><I><S><E><A><A><T><L><P><W><G><T><D><P><H><P><S><A><P><L><P><D><P><P><G><W><R><D><I><E><P><E><P><L><E><S><E><A><P><T><K><S... | Contributes to the epidermal integrity and skin barrier function. Plays a role in the lamellar granule (LG) secretory system and in the stratum corneum (SC) epithelial cell formation.<BOP> | Q9D709 |
P21939 | XYLB_LACPE | Xylulose kinase | Lactiplantibacillus | <M><S><A><V><V><L><G><I><D><L><G><T><S><A><V><K><V><S><A><I><D><K><Q><G><N><V><V><A><Q><A><S><A><K><Y><A><L><Q><Q><P><H><P><G><Y><S><E><Q><D><P><E><D><W><V><T><Q><T><T><Q><A><I><R><E><L><L><Q><Q><S><E><V><T><A><D><Q><I><E><G><L><S><Y><S><G><Q><M><H><G><L><V><L><L><D><E><S><A><T><V><L><R><P><A><I><L><W><N><D><T><R><T><T... | Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.<BOP> | P21939 |
B2GBZ2 | YBEY_LIMF3 | Endoribonuclease YbeY | Limosilactobacillus | <M><E><L><Q><L><R><D><H><T><E><G><K><L><Q><P><S><Q><E><R><L><A><E><K><A><L><A><Q><A><A><E><R><L><D><V><P><E><Q><A><E><M><S><L><T><F><V><L><N><P><E><I><R><E><L><N><R><D><Y><R><G><I><D><R><A><T><D><V><I><S><F><A><I><E><D><D><D><D><L><A><N><L><P><A><E><I><R><A><E><L><P><V><E><L><G><D><L><V><I><S><I><D><K><V><T><E><Q><A><L... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | B2GBZ2 |
Q2EF88 | YSL3_ARATH | Protein YELLOW STRIPE LIKE 3 | Arabidopsis | <M><R><S><M><M><M><E><R><E><G><R><N><E><I><E><R><E><V><I><D><D><L><E><E><T><Q><N><E><G><D><D><F><K><S><I><P><P><W><K><E><Q><I><T><F><R><G><I><V><A><S><L><I><I><G><I><I><Y><S><V><I><V><M><K><L><N><L><T><T><G><L><V><P><N><L><N><V><S><A><A><L><L><A><F><V><F><L><R><S><W><T><K><L><L><T><K><A><G><I><V><T><K><P><F><T><K><Q><E... | May be involved in the lateral transport of nicotianamine-chelated metals in the vasculature.<BOP> | Q2EF88 |
A7HKC0 | UVRB_FERNB | Excinuclease ABC subunit B | Fervidobacterium | <M><P><Y><E><L><I><S><D><Y><E><P><M><G><D><Q><P><Q><A><I><E><S><L><V><N><G><L><N><K><G><Y><R><F><Q><T><L><L><G><V><T><G><S><G><K><T><F><T><M><A><N><V><I><K><E><V><N><R><P><V><L><I><I><S><P><N><K><T><L><A><A><Q><L><Y><S><E><F><K><A><F><F><P><N><N><K><V><E><F><F><I><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V><P><T><K><D><L><Y><I... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | A7HKC0 |
Q498E2 | TDRP_RAT | Testis development-related protein | Rattus | <M><W><K><L><S><R><S><R><V><L><L><D><E><P><P><E><E><E><D><V><L><R><G><A><S><P><A><S><A><A><A><Q><A><P><G><A><S><L><R><G><W><K><E><A><T><S><L><F><N><K><D><D><E><E><R><L><L><E><T><S><R><S><S><K><S><K><G><T><N><V><R><L><K><E><E><L><K><A><E><K><K><S><G><F><W><D><A><L><V><L><K><Q><N><V><Q><P><K><K><P><D><Q><M><E><G><W><E><P... | Contributes to normal sperm motility, but not essential for male fertility.<BOP> | Q498E2 |
P07529 | XYNA_NAGAL | 1,4-beta-D-xylan xylanohydrolase | Naganishia | <M><L><S><S><T><T><L><L><A><I><L><S><A><L><A><L><T><S><V><Q><A><A><P><A><D><K><N><S><L><D><Y><L><A><N><K><A><G><K><R><Y><L><G><T><A><V><Q><S><P><Q><L><V><P><G><S><Q><Y><V><Q><I><L><E><S><Q><F><D><A><I><T><P><E><N><E><M><K><W><E><V><V><E><P><T><E><G><N><F><D><F><T><G><T><D><K><I><V><A><E><A><K><K><T><G><S><L><L><R><G><H... | Requires at least three xylose residues for catalytic activity. Does not have activity against xylobiose.<BOP> | P07529 |
Q0KEP0 | Y381_CUPNH | Nucleotide-binding protein H16_A0381 | Cupriavidus | <M><R><I><I><L><I><T><G><I><S><G><S><G><K><S><V><A><L><N><V><L><E><D><A><G><Y><Y><C><V><D><N><L><P><A><Q><F><I><P><E><L><T><R><Y><L><D><S><Q><G><Y><T><H><L><G><V><A><T><D><I><R><S><R><E><S><L><D><Q><L><P><D><T><V><R><A><L><A><A><E><H><Q><V><E><V><V><F><L><T><A><S><T><D><A><L><V><Q><R><Y><S><E><T><R><R><R><H><P><L><S><V... | Displays ATPase and GTPase activities.<BOP> | Q0KEP0 |
A5G9V4 | YIDC_GEOUR | Membrane protein YidC | Geotalea | <M><E><K><R><V><V><I><A><V><I><L><S><I><A><V><L><Y><A><Y><S><M><I><F><P><P><P><Q><K><K><D><V><V><K><P><G><P><V><P><Q><S><Q><T><A><P><V><Q><A><V><S><S><T><S><V><L><P><A><I><M><Q><Q><G><N><V><S><V><R><D><L><V><V><E><T><D><L><F><T><A><V><F><S><T><R><G><A><G><L><K><K><L><V><L><K><R><Y><K><E><T><S><G><P><G><G><R><E><V><V><L... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb... | A5G9V4 |
Q8I3Z5 | TCTP_PLAF7 | Translationally-controlled tumor protein homolog | Plasmodium (Laverania) | <M><K><V><F><K><D><V><F><T><N><D><E><V><C><S><D><S><Y><V><Q><Q><D><P><F><E><V><P><E><F><R><E><I><A><F><E><V><K><S><N><K><R><I><K><G><N><E><D><Y><G><I><A><D><N><S><E><D><A><V><E><G><M><G><A><D><V><E><H><V><I><D><I><V><D><S><F><Q><L><T><S><T><A><F><S><K><K><E><Y><S><A><Y><I><K><N><Y><M><Q><K><V><A><K><Y><L><E><E><K><K><P... | Involved in calcium binding and microtubule stabilization.<BOP> | Q8I3Z5 |
Q01WE6 | UPPP_SOLUE | Undecaprenyl pyrophosphate phosphatase | Candidatus Solibacter | <M><P><I><L><Q><V><I><V><L><A><V><V><Q><G><L><T><E><F><L><P><I><S><S><T><A><H><L><Y><L><T><S><W><L><L><G><W><Q><I><E><G><L><D><F><D><I><A><L><H><I><G><T><L><L><A><V><L><I><F><F><A><R><D><W><L><Q><I><I><A><Q><G><F><G><I><R><R><E><G><D><R><E><L><N><H><N><H><M><L><L><W><L><L><L><I><G><T><V><P><V><G><I><A><G><L><L><F><N><K... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | Q01WE6 |
Q91V04 | TRAM1_MOUSE | Translocating chain-associated membrane protein 1 | Mus | <M><A><I><R><K><K><S><N><K><N><P><P><L><L><S><H><E><F><L><L><Q><N><H><A><D><I><V><S><C><L><A><M><L><F><L><L><G><L><M><F><E><V><T><A><K><G><A><I><I><F><V><A><L><Q><Y><N><V><T><R><P><A><T><E><E><Q><A><T><E><S><A><S><L><Y><H><Y><G><I><K><D><L><A><T><V><L><F><Y><M><L><V><A><I><I><I><H><A><I><I><Q><E><Y><V><L><D><K><I><N><R... | Involved in the translocation of nascent protein chains into or through the endoplasmic reticulum (ER) membrane by facilitating the proper chain positioning at the SEC61 channel. Regulates the exposure of nascent secretory protein chain to the cytosol during translocation into the ER. May affect the phospholipid bilaye... | Q91V04 |
P39301 | ULAA_ECOLI | Ascorbate-specific permease IIC component UlaA | Escherichia | <M><E><I><L><Y><N><I><F><T><V><F><F><N><Q><V><M><T><N><A><P><L><L><L><G><I><V><T><C><L><G><Y><I><L><L><R><K><S><V><S><V><I><I><K><G><T><I><K><T><I><I><G><F><M><L><L><Q><A><G><S><G><I><L><T><S><T><F><K><P><V><V><A><K><M><S><E><V><Y><G><I><N><G><A><I><S><D><T><Y><A><S><M><M><A><T><I><D><R><M><G><D><A><Y><S><W><V><G><Y><A... | The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.<BOP... | P39301 |
Q8KGG3 | YIDD_CHLTE | Putative membrane protein insertion efficiency factor | Chlorobaculum | <M><N><I><V><P><I><L><L><I><R><F><Y><Q><S><F><I><S><P><L><L><G><P><S><C><K><Y><H><P><T><C><S><N><Y><A><I><E><A><F><R><Q><H><N><F><F><Y><A><S><W><L><T><V><W><R><V><L><R><C><N><P><F><S><K><G><G><Y><D><P><V><P><P><K><S><V><K><S><A><G><N><S><K><D><S><K> | Could be involved in insertion of integral membrane proteins into the membrane.<BOP> | Q8KGG3 |
F1Q7H8 | ZD20A_DANRE | Zinc finger DHHC domain-containing protein 20-A | Danio | <M><A><P><S><H><A><V><R><C><C><Q><R><G><L><S><W><I><P><V><I><F><I><N><L><V><V><C><W><S><Y><Y><A><Y><V><V><E><L><C><I><Y><T><I><P><N><V><N><E><Q><V><I><Y><L><V><V><F><H><A><F><F><F><M><F><M><W><S><Y><W><K><T><I><S><S><K><P><T><N><P><S><K><E><F><C><L><P><K><A><E><K><E><L><Y><E><K><E><E><R><P><E><A><Q><Q><D><I><L><K><R><V... | Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates. Catalyzes palmitoylation of Cys residues on protein substrates and has a preference for acyl-CoA with C16 fatty acid chains but may also utilize acyl-CoA with C14 and C18 fatty acid chains.<BOP> | F1Q7H8 |
B7UTC1 | YEGS_ECO27 | Probable lipid kinase YegS | Escherichia | <M><A><E><F><P><A><S><L><L><I><L><N><G><K><S><T><D><N><L><P><L><R><E><A><I><M><L><L><R><E><E><G><M><T><I><H><V><R><V><T><W><E><K><G><D><A><V><R><F><V><E><E><A><R><K><L><G><V><A><T><V><I><A><G><G><G><D><G><T><I><N><E><V><S><T><A><L><I><Q><C><E><G><D><D><I><P><A><L><G><I><L><P><L><G><T><A><N><D><F><A><T><S><V><G><I><P><E... | Probably phosphorylates lipids; the in vivo substrate is unknown.<BOP> | B7UTC1 |
P56811 | TFX_METTM | DNA-binding protein Tfx | Methanothermobacter | <M><S><K><K><T><F><L><T><E><R><Q><K><T><V><L><E><M><R><E><R><G><W><S><Q><K><K><I><A><R><E><L><K><T><T><R><Q><N><V><S><A><I><E><R><K><A><M><E><N><I><E><K><S><R><N><T><L><D><F><V><K><F><L><K><S><P><V><R><I><L><C><R><R><G><D><T><L><D><E><I><I><K><R><L><L><E><E><S><N><K><E><G><I><H><V><I><H><D><S><I><T><L><A><F><L><I><R><E... | Transcriptional activator of the fmdECB operon.<BOP> | P56811 |
Q9NFZ4 | TPM_LEPDS | Tropomyosin | Lepidoglyphus | <M><E><A><I><K><N><K><M><Q><A><M><K><L><E><K><D><N><A><I><D><R><A><E><I><A><E><Q><K><S><R><D><A><N><L><R><A><E><K><S><E><E><E><V><R><G><L><Q><K><K><I><Q><Q><I><E><N><E><L><D><Q><V><Q><E><S><L><T><Q><A><N><T><K><L><E><E><K><E><K><S><L><Q><T><A><E><G><D><V><A><A><L><N><R><R><I><Q><L><I><E><E><D><L><E><R><S><E><G><R><L><K... | Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.<BOP> | Q9NFZ4 |
Q3BMF4 | TTCA_XANC5 | tRNA 2-thiocytidine biosynthesis protein TtcA | Xanthomonas | <M><T><A><V><L><P><L><P><Q><P><L><A><D><P><A><P><R><D><P><R><Q><R><L><Q><R><E><Q><L><R><L><G><K><R><L><Q><R><Q><V><G><Q><A><I><A><D><F><G><M><I><A><P><G><D><K><V><M><V><C><L><S><G><G><K><D><S><Y><T><L><L><D><M><L><L><Q><L><Q><R><K><A><P><V><P><F><S><L><V><A><V><N><L><D><Q><K><Q><P><D><F><P><A><H><V><L><P><A><Y><L><R><G... | Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.<BOP> | Q3BMF4 |
A4IRT9 | THII_GEOTN | tRNA 4-thiouridine synthase | Geobacillus | <M><K><Y><D><R><I><L><I><R><Y><G><E><M><T><T><K><G><K><N><R><N><I><F><V><R><R><L><K><N><N><I><A><R><K><L><Q><A><F><P><R><I><K><I><E><Y><M><R><D><R><M><Y><I><L><L><N><G><E><P><H><E><P><I><I><D><K><L><K><T><V><F><G><I><H><S><F><S><L><A><M><K><C><E><N><D><L><A><A><I><K><E><T><A><L><A><A><V><R><Q><L><P><Y><K><G><K><T><F><K... | Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt... | A4IRT9 |
Q9ZMZ5 | UREE_HELPJ | Urease accessory protein UreE | Helicobacter | <M><I><I><E><R><L><V><G><N><L><R><D><L><N><P><L><D><F><N><V><D><H><V><D><L><E><W><F><E><T><R><K><K><I><A><R><F><K><T><R><Q><G><K><D><I><A><I><R><L><K><D><A><P><K><L><G><L><S><Q><G><D><I><L><F><K><E><E><K><E><I><I><A><V><N><I><L><D><S><E><V><I><H><I><Q><A><K><S><V><A><E><V><A><K><I><C><Y><E><I><G><N><R><H><A><A><L><Y><Y... | Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.<BOP> | Q9ZMZ5 |
P45142 | TRUB_HAEIN | tRNA-uridine isomerase | Haemophilus | <M><S><R><P><R><K><R><W><R><D><V><D><G><V><F><L><L><D><K><P><Q><G><M><S><S><N><D><I><M><Q><K><V><K><R><L><F><Q><A><N><K><A><G><H><T><G><A><L><D><P><L><A><T><G><M><L><P><I><C><L><G><E><A><T><K><F><S><Q><F><L><L><D><A><D><K><R><Y><L><V><T><A><K><L><G><E><R><T><D><T><S><D><A><E><G><Q><V><V><E><T><R><E><V><N><L><E><T><Q><Q... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | P45142 |
P9WGC8 | TSAC_MYCTO | tRNA threonylcarbamoyladenosine biosynthesis protein MT1340 | Mycobacterium tuberculosis complex | <M><T><E><T><F><D><C><A><D><P><E><Q><R><S><R><G><I><V><S><A><V><G><A><I><K><A><G><Q><L><V><V><M><P><T><D><T><V><Y><G><I><G><A><D><A><F><D><S><S><A><V><A><A><L><L><S><A><K><G><R><G><R><D><M><P><V><G><V><L><V><G><S><W><H><T><I><E><G><L><V><Y><S><M><P><D><G><A><R><E><L><I><R><A><F><W><P><G><A><L><S><L><V><V><V><Q><A><P><S... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.<BOP> | P9WGC8 |
Q6MP18 | TPIS_BDEBA | Triose-phosphate isomerase | Bdellovibrio | <M><K><K><I><F><A><A><N><W><K><L><F><K><S><P><K><E><T><R><E><F><F><G><Q><F><K><E><L><A><G><K><A><T><G><E><V><V><F><F><P><S><A><I><S><L><E><A><A><S><E><S><L><K><G><T><S><I><K><F><G><A><Q><N><C><Y><F><Q><A><Q><G><A><F><T><G><E><N><S><A><Q><V><V><K><D><L><G><G><S><Y><V><L><I><G><H><S><E><R><R><A><I><F><G><E><G><D><A><L><V... | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP> | Q6MP18 |
A3P8N2 | TYPH_BURP0 | TdRPase | pseudomallei group | <M><T><F><L><P><Q><E><F><I><R><K><V><R><D><R><A><P><L><D><T><A><D><V><A><R><F><V><Q><G><V><T><A><G><D><V><T><E><G><Q><I><A><A><F><A><M><A><V><Y><F><N><E><L><P><L><S><A><R><I><A><L><T><L><A><Q><R><D><S><G><D><V><L><D><W><R><G><A><R><L><N><G><P><V><V><D><K><H><S><T><G><G><V><G><D><L><T><S><L><V><I><G><P><M><V><A><A><C><G... | The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.<BOP> | A3P8N2 |
Q4KL14 | TPC3L_MOUSE | BET3-like protein | Mus | <M><S><R><P><A><H><K><R><P><E><Y><H><K><I><N><K><D><L><F><V><L><T><Y><G><A><L><V><A><Q><L><C><K><D><Y><E><K><D><E><D><V><N><K><Y><L><D><K><M><G><Y><N><I><G><T><R><L><V><E><D><F><L><A><R><S><C><V><R><R><C><H><S><Y><S><E><I><I><N><I><I><A><Q><V><A><F><K><M><Y><L><G><I><T><P><S><V><T><C><H><N><S><S><R><N><E><F><S><L><I><L... | May play a role in vesicular transport from endoplasmic reticulum to Golgi.<BOP> | Q4KL14 |
P15620 | ZN271_MOUSE | Zinc finger protein 35 | Mus | <M><E><I><Q><F><S><Y><E><S><Q><D><H><H><F><L><S><D><G><E><T><K><I><K><I><G><E><P><A><T><E><E><E><M><T><G><K><I><G><T><V><T><E><E><S><G><S><L><E><E><D><V><P><H><D><S><R><G><K><E><F><R><E><F><G><E><E><L><N><D><Q><M><L><F><R><R><R><Q><Y><N><C><D><E><C><D><Q><S><F><A><W><S><T><G><L><I><R><H><Q><R><T><H><W><K><P><Y><E><C><E... | May act to control gene activity during the pachytene stage of meiotic prophase. May function as a transcription activator.<BOP> | P15620 |
B5EI26 | TIG_CITBB | PPIase | Citrifermentans | <M><Q><I><S><V><E><S><V><N><S><I><K><K><K><L><N><F><E><I><P><A><D><K><V><S><A><E><V><D><K><A><Y><A><E><I><R><K><H><A><A><I><K><G><F><R><K><G><K><V><P><M><S><L><I><E><K><H><Y><G><E><K><M><A><E><D><V><V><K><N><L><V><Q><E><S><Y><F><S><A><V><S><E><Q><G><L><N><P><V><G><Y><P><A><I><E><S><N><P><L><K><K><G><E><S><F><K><Y><S><A... | Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP> | B5EI26 |
Q8REL0 | UVRC_FUSNN | Excinuclease ABC subunit C | Fusobacterium | <M><D><I><G><K><I><D><I><P><E><S><S><G><V><Y><L><M><K><K><N><N><K><V><I><Y><V><G><K><A><K><N><L><K><N><R><V><S><S><Y><F><N><R><V><H><E><S><E><K><T><N><E><L><V><K><N><I><E><D><I><E><F><F><L><T><N><T><E><I><D><A><L><L><L><E><N><N><L><I><K><K><Y><S><P><K><Y><N><I><L><L><K><D><E><K><T><Y><P><F><I><K><I><S><K><E><D><F><S><S... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | Q8REL0 |
Q7UM42 | TSAD_RHOBA | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Rhodopirellula | <M><T><P><T><A><A><S><E><L><L><L><S><I><E><S><T><C><D><E><T><A><A><A><V><I><R><R><D><G><T><V><L><G><Q><C><I><A><T><Q><E><T><L><H><E><Q><F><G><G><V><V><P><E><I><A><A><R><A><H><L><E><R><I><L><P><V><I><D><T><A><L><T><Q><A><K><V><R><G><E><D><L><T><A><I><A><V><A><D><R><P><G><L><A><G><S><L><L><V><G><V><V><A><A><K><T><L><A><L... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q7UM42 |
A4XTM7 | TAL_PSEMY | Transaldolase | Pseudomonas | <M><T><S><K><L><E><Q><L><K><Q><F><T><T><V><V><A><D><T><G><D><L><D><A><I><A><R><L><K><P><V><D><A><T><T><N><P><S><L><L><L><K><A><A><S><L><P><G><Y><A><D><L><L><K><Q><A><V><S><T><G><K><G><D><P><G><L><A><C><D><H><F><A><V><A><V><G><Q><E><I><L><K><V><I><P><G><R><I><S><T><E><V><D><A><R><L><S><F><D><T><G><A><T><L><L><R><A><E><R... | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP> | A4XTM7 |
A0Q1Q3 | YBEY_CLONN | Endoribonuclease YbeY | Clostridium | <M><I><Y><I><D><N><R><Q><D><K><I><K><I><D><E><K><T><L><N><T><L><D><E><I><I><K><Y><A><L><K><E><E><E><V><Y><V><N><T><E><V><S><V><I><L><I><D><N><D><T><I><K><E><I><N><K><E><T><R><D><I><D><K><V><T><D><V><L><S><F><P><M><L><D><Y><P><K><G><K><T><Y><K><E><V><Y><K><D><Y><E><F><D><A><S><Y><L><D><E><G><E><L><V><L><G><D><I><V><L><S... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | A0Q1Q3 |
Q6GJG2 | TILS_STAAR | tRNA(Ile)-lysidine synthetase | Staphylococcus | <M><Q><L><N><S><N><G><W><H><V><D><D><H><I><V><V><A><V><S><T><G><I><D><S><M><C><L><L><Y><Q><L><L><N><D><Y><K><D><S><Y><R><K><L><T><C><L><H><V><N><H><G><V><R><S><A><S><I><E><E><A><R><F><L><E><A><Y><C><E><R><H><H><I><D><L><H><I><K><K><L><D><L><S><H><S><L><N><R><N><N><S><I><Q><N><E><A><R><I><K><R><Y><E><W><F><D><E><M><M><N... | Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP> | Q6GJG2 |
A4WG70 | ZAPB_ENT38 | Cell division protein ZapB | Enterobacter | <M><T><M><S><L><E><V><F><E><K><L><E><S><K><V><Q><Q><A><I><D><T><I><T><L><L><Q><M><E><I><E><E><L><K><E><K><N><N><A><L><A><Q><E><V><H><S><A><Q><N><G><R><E><E><L><E><R><E><N><Q><Q><L><R><E><Q><Q><N><G><W><Q><D><R><L><Q><A><L><L><G><R><M><E><E><V> | Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.<BOP... | A4WG70 |
P95508 | YIHI_MANHA | Der GTPase-activating protein YihI | Mannheimia | <M><S><R><T><K><K><T><R><R><I><T><D><I><M><P><A><R><K><T><D><K><P><K><Q><P><M><P><K><L><G><G><G><K><N><R><K><L><T><R><Y><E><L><D><A><Q><A><R><E><E><K><R><K><R><K><H><K><G><L><P><T><G><S><R><N><A><D><P><A><E><Q><K><K><A><V><V><K><E><V><K><D><P><R><I><G><S><R><K><K><V><P><L><M><V><E><F><V><N><Q><P><E><K><G><R><T><I><K><A... | A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.<BOP> | P95508 |
Q5Y4U2 | TXAG1_AGEOR | AgorTX_B7b | Agelena | <M><C><V><A><T><C><L><C><T><F><A><Y><V><L><A><K><S><D><E><G><E><N><L><I><S><K><V><E><E><T><Q><R><G><C><I><E><I><G><G><D><C><D><G><Y><L><D><K><S><Y><C><Q><C><C><R><N><N><G><F><C><S><C><Y><K><V><P><E><W><F><G><Y><K><V><G><C><K><C><S><V><D><W><N><F><V><G><W><C><R><L><K><Q><F><C><P><G><G><S><Q><N><P><S><L><C><K><D><P><N><P... | Inhibits voltage-gated calcium channels (Cav).<BOP> | Q5Y4U2 |
Q9ZQZ9 | TI204_ARATH | Translocon at the inner envelope membrane of chloroplasts 20-IV | Arabidopsis | <M><Q><G><L><A><A><T><T><T><N><R><G><S><L><T><F><L><A><P><R><N><H><S><P><I><S><K><K><F><V><N><P><R><V><F><F><P><N><V><D><S><S><A><K><L><R><L><S><A><S><S><I><S><R><R><C><P><R><E><I><A><P><L><S><A><T><A><S><V><D><F><A><A><A><A><T><S><S><N><Q><L><F><A><N><G><L><P><P><L><A><P><G><L><R><R><H><R><R><P><I><E><P><A><R><V><A><K... | Involved in protein precursor import into chloroplasts. Partially redundant with TIC20-I, but not with TIC20-II or TIC20-V.<BOP> | Q9ZQZ9 |
Q732R2 | TRUB_BACC1 | tRNA-uridine isomerase | Bacillus cereus group | <M><E><G><V><V><L><L><H><K><P><K><G><M><T><S><H><D><C><I><F><K><L><R><K><I><L><R><E><K><R><I><G><H><T><G><T><L><D><P><D><V><T><G><V><L><P><I><C><V><G><R><A><T><K><I><A><Q><F><L><T><S><E><T><K><T><Y><E><G><E><V><T><L><G><F><S><T><T><T><E><D><A><S><G><E><V><V><E><T><K><H><V><D><R><V><I><T><R><K><E><V><E><E><V><L><A><A><L... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | Q732R2 |
Q7VKR6 | THII_HAEDU | tRNA 4-thiouridine synthase | Haemophilus | <M><K><F><I><I><K><L><F><P><E><I><M><I><K><S><D><S><V><R><K><R><F><I><K><I><L><T><S><N><I><R><N><V><L><L><R><E><T><E><Q><V><A><V><V><R><N><W><D><F><I><E><V><R><A><K><V><A><E><E><I><P><L><I><L><D><L><L><K><R><T><P><G><I><H><H><I><L><E><V><Q><E><M><P><F><T><S><L><H><D><I><F><E><H><T><F><A><K><Y><Q><N><Q><L><V><D><K><T><F... | Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt... | Q7VKR6 |
Q6GL39 | WDR82_XENTR | WD repeat-containing protein 82 | Silurana | <M><K><L><T><D><N><V><L><R><S><F><R><V><A><K><V><F><R><E><N><S><D><K><I><N><C><F><D><F><S><P><T><G><E><T><V><I><S><S><S><D><D><D><S><I><V><L><Y><D><C><Q><E><G><K><P><K><R><T><L><Y><S><K><K><Y><G><V><D><L><I><R><Y><T><H><A><A><N><T><V><V><Y><S><S><N><K><I><D><D><T><I><R><Y><L><S><L><H><D><N><K><Y><I><R><Y><F><P><G><H><S... | Regulatory component of the SET1 complex implicated in the tethering of this complex to transcriptional start sites of active genes. Facilitates histone H3 'Lys-4' methylation (H3K4me) via recruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylated C-terminal domain (CTD) of RNA polymerase II large subunit (POLR2... | Q6GL39 |
P37752 | TRMO_EIKCO | tRNA methyltransferase O | Eikenella | <S><F><S><H><I><W><V><Q><F><V><F><H><G><V><A><G><A><G><W><Q><P><L><V><R><P><P><R><L><G><G><N><R><K><M><G><V><F><A><T><R><S><P><F><R><P><N><P><L><G><L><S><L><L><K><L><E><R><I><E><T><E><G><G><V><R><L><W><C><G><G><A><D><L><L><D><G><T><P><V><L><D><I><K><P><Y><L><P><F><V><E><A><Q><P><D><A><A><P><G><F><A><A><V><P><P><V><P><L... | S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Thr)(GGU). The methyl group of m(6)t(6)A37 appears to slightly improve the efficiency of the tR... | P37752 |
P05483 | U7AB_CONGE | Shaker peptides GVIIA/GVIIB | Gastridium | <C><K><S><P><G><T><P><C><S><R><G><M><R><D><C><C><T><S><C><L><L><Y><S><N><K><C><R><R><Y> | Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).<BOP> | P05483 |
P29962 | Y1784_RHOCB | ORF124 | Rhodobacter | <M><A><P><R><E><P><G><F><A><G><A><L><P><I><D><G><Y><G><P><G><F><F><R><I><A><G><A><V><H><R><G><G><L><L><I><H><A><E><A><A><M><P><W><T><G><F><D><D><L><A><A><L><R><A><L><A><G><Q><V><D><L><L><L><C><G><M><G><A><D><I><A><H><L><P><K><G><L><Q><V><E><L><E><A><L><G><V><M><A><E><P><M><S><T><A><S><A><A><R><H><Y><N><V><L><L><S><E><G... | Not required for the biogenesis of c-type cytochromes.<BOP> | P29962 |
Q13454 | TUSC3_HUMAN | Protein N33 | Homo | <M><G><A><R><G><A><P><S><R><R><R><Q><A><G><R><R><L><R><Y><L><P><T><G><S><F><P><F><L><L><L><L><L><L><L><C><I><Q><L><G><G><G><Q><K><K><K><E><N><L><L><A><E><K><V><E><Q><L><M><E><W><S><S><R><R><S><I><F><R><M><N><G><D><K><F><R><K><F><I><K><A><P><P><R><N><Y><S><M><I><V><M><F><T><A><L><Q><P><Q><R><Q><C><S><V><C><R><Q><A><N><E... | Magnesium transporter.<BOP> | Q13454 |
Q88W46 | TARI_LACPL | Ribitol-5-phosphate cytidylyltransferase | Lactiplantibacillus | <M><I><Y><A><Q><I><L><A><G><G><K><G><T><R><M><G><N><V><P><M><P><K><Q><F><L><L><L><A><D><K><P><I><L><I><H><T><I><E><K><F><T><L><E><S><R><F><D><A><I><L><V><V><C><P><A><D><W><V><S><H><T><E><D><I><I><K><K><Y><I><T><D><E><R><V><H><V><V><V><G><G><A><D><R><N><E><T><L><M><S><G><I><N><Y><I><Q><D><H><Y><G><I><Q><D><D><D><V><V><V... | Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.<BOP> | Q88W46 |
B3CU37 | YQGF_ORITI | Putative pre-16S rRNA nuclease | Orientia | <M><I><I><N><S><I><I><E><F><L><Q><A><A><D><I><K><K><Q><I><L><G><I><D><F><G><E><K><K><V><G><V><A><I><S><N><I><E><H><T><V><A><M><P><L><Q><T><I><F><A><T><N><Q><D><R><I><N><K><I><Q><E><I><A><V><A><Y><N><I><G><A><I><V><I><G><L><P><F><K><L><D><G><T><E><T><S><Q><T><H><R><V><K><D><F><A><N><K><L><A><N><K><L><L><L><P><I><F><L><C... | Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP> | B3CU37 |
P29037 | TBP_MOUSE | Transcription initiation factor TFIID TBP subunit | Mus | <M><D><Q><N><N><S><L><P><P><Y><A><Q><G><L><A><S><P><Q><G><A><M><T><P><G><I><P><I><F><S><P><M><M><P><Y><G><T><G><L><T><P><Q><P><I><Q><N><T><N><S><L><S><I><L><E><E><Q><Q><R><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><A><V><A><T><A><A><A><S><V><Q><Q><S><T><S><Q><Q><P><T><Q><G><A><S><G><Q><T><P><Q><L><F><H><S><Q><T><L><T><T><A... | General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of a BRF2-conta... | P29037 |
O74000 | Y106A_PYRHO | Putative antitoxin PH1062.1 | Pyrococcus | <M><S><K><T><I><T><I><A><D><D><V><Y><Y><E><L><V><K><M><K><G><K><R><S><F><S><E><V><L><R><E><L><I><G><K><K><K><E><G><N><L><D><V><L><M><I><A><F><G><T><M><D><E><E><E><A><K><E><L><E><E><K><I><K><E><V><G><K><W><L><N><S><W><T><P><V> | Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.<BOP> | O74000 |
B1LE44 | YDIB_ECOSM | NAD-dependent shikimate 5-dehydrogenase | Escherichia | <M><N><V><T><A><K><Y><E><L><I><G><L><M><A><Y><P><I><R><H><S><L><S><P><E><M><Q><N><K><A><L><E><K><A><G><L><P><F><T><Y><M><A><F><E><V><D><N><D><S><F><P><A><A><I><E><G><L><K><A><L><K><M><R><G><T><G><V><S><M><P><N><K><Q><L><A><C><E><Y><V><D><E><L><T><P><A><A><K><L><V><G><A><I><N><T><I><V><N><D><D><G><Y><L><R><G><Y><N><T><D... | The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD o... | B1LE44 |
B2I7H1 | TTCA_XYLF2 | tRNA 2-thiocytidine biosynthesis protein TtcA | Xylella | <M><D><A><T><F><P><S><Q><H><N><I><T><A><R><P><A><P><G><R><I><R><R><E><Q><C><K><L><A><K><R><L><R><R><Q><V><G><Q><A><I><A><D><F><G><M><I><E><A><N><D><K><I><M><V><C><L><S><G><G><K><D><S><Y><T><L><L><D><M><L><L><Q><L><R><A><K><A><P><V><P><F><E><L><T><A><V><N><L><D><Q><K><Q><P><G><F><P><K><H><V><L><P><E><Y><L><S><S><I><G><V... | Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.<BOP> | B2I7H1 |
Q4V7R0 | TIGAR_XENLA | TP53-induced glycolysis and apoptosis regulator | Xenopus | <M><A><R><F><A><L><T><I><V><R><H><G><E><T><R><Y><N><K><E><K><L><L><Q><G><Q><G><I><D><E><P><L><S><E><M><G><F><K><Q><A><D><A><A><G><R><F><L><S><N><V><R><F><T><H><V><F><S><S><D><L><I><R><A><K><Q><T><A><C><A><I><M><R><N><N><Q><L><S><E><D><I><K><I><M><Y><D><P><R><L><R><E><R><K><Y><G><D><A><E><G><R><P><L><S><E><L><K><V><M><A... | Fructose-bisphosphatase hydrolyzing fructose-2,6-bisphosphate as well as fructose-1,6-bisphosphate. Acts as a negative regulator of glycolysis by lowering intracellular levels of fructose-2,6-bisphosphate in a p53/TP53-dependent manner, resulting in the pentose phosphate pathway (PPP) activation and NADPH production. C... | Q4V7R0 |
Q28K11 | TRUB_JANSC | tRNA-uridine isomerase | unclassified Jannaschia | <M><A><R><R><N><K><G><R><D><I><S><G><W><V><L><V><D><K><P><A><G><L><T><S><T><A><V><V><N><K><V><R><W><C><F><D><A><K><K><A><G><H><A><G><T><L><D><P><D><A><T><G><M><L><P><V><A><L><G><E><A><T><K><T><I><A><Y><M><S><D><D><L><K><A><Y><T><F><R><V><R><L><G><V><S><T><K><T><D><D><A><E><G><E><V><L><E><T><S><D><T><R><P><T><D><T><E><I... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | Q28K11 |
Q984P3 | UVRC_RHILO | Excinuclease ABC subunit C | Mesorhizobium | <M><S><P><L><D><Q><K><N><K><P><R><G><G><A><D><D><L><P><P><E><I><D><L><E><D><E><A><L><E><E><I><V><E><P><T><G><P><D><V><A><F><T><A><I><D><W><T><P><H><A><G><D><A><E><G><M><V><G><A><E><V><I><Q><T><L><V><K><R><L><P><N><A><P><G><V><Y><R><M><M><N><A><A><G><D><V><L><Y><V><G><K><A><R><S><L><K><K><R><V><T><N><Y><A><Q><G><R><F><H... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | Q984P3 |
Q5NYM6 | YCIB_AROAE | Inner membrane-spanning protein YciB | Aromatoleum | <M><K><I><L><F><D><L><L><P><V><I><L><F><F><V><A><Y><K><I><A><G><G><N><Q><A><F><A><H><E><L><A><S><R><W><L><G><D><G><I><A><V><T><Q><A><P><I><L><L><A><T><A><V><A><I><L><A><T><I><A><Q><I><G><W><V><W><M><R><H><R><K><V><D><T><M><L><W><I><S><L><A><I><I><A><V><F><G><G><A><T><L><F><F><H><N><P><T><F><I><K><W><K><P><T><A><L><Y><W... | Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP> | Q5NYM6 |
Q5D7I5 | TRIM5_CEBPY | TRIM5alpha | Cebuella | <M><A><S><R><I><L><V><N><I><K><E><E><V><T><C><P><I><C><L><E><L><L><T><E><P><L><S><L><D><C><G><H><S><F><C><Q><A><C><I><T><A><N><H><K><E><S><T><L><H><Q><G><E><R><S><C><P><L><C><R><M><S><Y><P><S><E><N><L><R><P><N><R><H><L><A><N><I><V><E><R><L><K><E><V><M><L><S><P><E><E><G><Q><K><V><D><H><C><A><R><H><G><E><K><L><L><L><F><C... | Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates i... | Q5D7I5 |
A0A291PQG3 | UGT4_DACCO | UDP-glucosyltransferase 4 | Dactylopius | <M><T><L><L><R><D><L><L><L><L><Y><I><N><S><L><L><F><I><N><P><S><I><G><E><N><I><L><V><F><L><P><T><K><T><Y><S><H><F><K><P><L><E><P><L><F><Q><E><L><A><M><R><G><H><N><V><T><V><F><S><G><F><S><L><T><K><N><I><S><N><Y><S><S><I><V><F><S><A><E><I><E><F><V><N><I><G><M><G><N><L><R><K><Q><S><R><I><Y><N><W><I><Y><V><H><N><E><L><Q><N... | Catalyzes the transfer of a glycosyl group from a UDP-sugar to an acceptor molecule.<BOP> | A0A291PQG3 |
Q03Y35 | YBEY_LEUMM | Endoribonuclease YbeY | Leuconostoc | <M><D><L><A><I><I><D><Q><T><K><A><G><V><N><Q><Y><H><Q><D><L><V><R><C><V><L><D><Y><A><G><K><Y><L><E><L><P><D><N><T><E><M><S><V><T><F><M><N><N><E><E><I><H><Q><Y><N><K><K><Y><R><G><I><D><K><P><T><D><V><I><S><F><A><I><E><E><D><G><D><D><L><P><V><L><P><D><E><L><M><D><A><E><L><A><K><N><I><G><D><I><L><V><S><V><D><I><I><N><S><Q... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q03Y35 |
A1K2P1 | UBIA_AZOSB | 4-HB polyprenyltransferase | Azoarcus | <M><T><L><S><D><R><L><P><L><Y><G><R><L><M><R><L><D><K><P><I><G><S><L><L><L><L><W><P><T><L><W><A><L><W><L><A><A><D><G><K><P><P><L><H><V><L><V><I><F><T><I><G><T><V><L><M><R><S><A><G><C><V><I><N><D><Y><A><D><R><D><F><D><G><H><V><E><R><T><R><N><R><P><L><A><T><R><A><V><S><T><R><E><A><L><A><L><A><A><G><L><S><A><L><S><F><V><L... | Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-... | A1K2P1 |
Q9FH40 | TA14B_ARATH | TBP-associated factor 14b | Arabidopsis | <M><T><N><S><S><S><S><K><K><Q><A><Q><D><Q><P><E><T><S><E><P><T><L><K><S><L><K><T><K><M><T><K><S><D><E><K><Q><K><K><L><K><D><I><E><I><S><V><P><I><V><Y><G><N><V><A><F><W><L><G><K><K><A><S><E><Y><Q><S><H><K><W><A><V><Y><V><R><G><A><T><N><E><D><I><S><V><V><V><K><K><V><V><F><Q><L><H><S><S><F><N><S><P><T><R><V><I><E><E><P><P... | Negative regulator of flowering controlling the H4K5 acetylation levels in the FLC and FT chromatin. Positively regulates FLC expression. Component of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription. Component of the SWR1 complex which mediates the... | Q9FH40 |
Q7T046 | VM3CX_MACLB | Coagulation factor X-activating enzyme heavy chain alternate form | Macrovipera | <M><M><Q><V><L><L><V><T><I><S><L><A><V><F><P><Y><Q><G><S><S><I><I><L><E><S><G><N><V><N><D><Y><E><V><V><Y><P><Q><K><I><T><A><L><P><E><E><A><V><Q><Q><P><E><Q><K><Y><E><D><T><M><Q><Y><E><F><E><V><N><G><E><P><V><V><L><H><L><E><K><N><K><D><L><F><S><E><D><Y><S><E><T><R><Y><S><P><D><G><R><E><T><T><T><K><P><P><V><Q><D><H><C><Y... | Catalytic subunit of blood coagulation factor X-activating enzyme. Activates coagulation factor X (F10) by cleaving the Arg(234)-Ile(235) bond, activates coagulation factor IX (F9) by cleaving the Arg(226)-Val(227) bond and is also able to activate protein C (PROC).<BOP> | Q7T046 |
Q63HD6 | TILS_BACCZ | tRNA(Ile)-lysidine synthetase | Bacillus cereus group | <M><K><D><T><F><V><E><K><V><D><D><F><V><K><Q><H><D><V><L><K><E><H><S><T><I><V><V><G><V><S><G><G><P><D><S><L><A><L><L><Y><Y><L><L><E><K><R><A><A><K><Q><F><E><I><V><V><A><H><V><D><H><M><F><R><G><D><E><S><H><E><D><L><Q><F><V><Q><D><L><C><K><G><L><G><V><I><C><E><T><I><R><I><N><V><S><Q><Y><Q><Q><Q><Y><G><M><N><A><Q><V><A><A... | Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP> | Q63HD6 |
Q52377 | UVRC_PSEU2 | Excinuclease ABC subunit C | Pseudomonas syringae | <M><T><Q><T><F><D><P><G><A><F><L><A><T><C><S><G><R><P><G><V><Y><R><M><F><D><A><E><A><T><L><L><Y><V><G><K><A><K><N><L><K><K><R><L><A><S><Y><F><R><K><T><G><H><A><P><K><T><G><A><L><V><S><R><I><A><Q><I><E><T><T><I><T><G><N><E><T><E><A><L><L><L><E><Q><T><L><I><K><E><W><R><P><P><Y><N><I><L><L><R><D><D><K><S><Y><P><Y><V><F><L... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | Q52377 |
Q4N938 | TCTP_THEPA | Translationally-controlled tumor protein homolog | Theileria | <M><K><V><Y><K><D><L><Y><S><N><D><E><V><C><S><D><A><Y><D><H><H><D><P><F><D><N><A><D><L><S><S><V><A><F><E><V><K><T><S><K><V><P><K><G><E><E><D><Y><G><I><G><Y><N><D><E><E><G><A><D><Q><M><N><V><D><P><N><V><E><M><V><V><D><V><V><D><K><F><G><L><Q><S><L><S><L><T><K><K><D><Y><S><S><Y><I><R><K><Y><I><Q><R><L><V><A><T><L><Q><E><K... | Involved in calcium binding and microtubule stabilization.<BOP> | Q4N938 |
Q17WX3 | TRUD_HELAH | tRNA-uridine isomerase D | Helicobacter | <M><N><L><N><F><M><P><L><L><H><A><Y><N><H><A><S><I><D><F><H><F><N><S><S><A><R><D><F><C><V><H><E><V><P><L><Y><E><F><S><N><K><G><E><H><A><I><I><Q><V><R><K><S><G><L><S><T><L><E><M><L><Q><I><F><S><Q><I><L><G><V><K><I><A><E><L><G><Y><A><G><L><K><D><K><N><A><L><T><T><Q><F><V><S><L><P><K><K><Y><A><P><L><L><E><K><N><T><S><N><F... | Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP> | Q17WX3 |
O00300 | TR11B_HUMAN | Osteoprotegerin | Homo | <M><N><N><L><L><C><C><A><L><V><F><L><D><I><S><I><K><W><T><T><Q><E><T><F><P><P><K><Y><L><H><Y><D><E><E><T><S><H><Q><L><L><C><D><K><C><P><P><G><T><Y><L><K><Q><H><C><T><A><K><W><K><T><V><C><A><P><C><P><D><H><Y><Y><T><D><S><W><H><T><S><D><E><C><L><Y><C><S><P><V><C><K><E><L><Q><Y><V><K><Q><E><C><N><R><T><H><N><R><V><C><E><C... | Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcifica... | O00300 |
Q25113 | TBXT_HEMPU | Protein T | Hemicentrotus | <M><P><A><M><S><A><D><A><L><R><A><P><S><Y><N><V><S><H><L><L><N><A><V><Q><S><E><M><N><R><G><S><E><K><G><D><P><S><E><E><G><L><K><V><R><L><D><D><V><E><L><W><K><K><F><H><K><L><T><N><E><M><I><V><T><K><S><G><R><R><M><F><P><V><L><S><A><S><I><A><G><L><D><P><N><S><M><Y><S><V><L><L><D><F><S><A><A><D><D><H><R><W><K><Y><V><N><G><E... | Involved in the transcriptional regulation of genes required for mesoderm differentiation.<BOP> | Q25113 |
Q5BBK9 | VPS27_EMENI | Vacuolar protein sorting-associated protein 27 | Aspergillus subgen. Nidulantes | <M><A><G><W><F><S><S><A><S><P><L><D><E><Q><I><E><R><A><T><A><S><S><L><E><D><I><A><L><N><L><E><I><S><D><L><I><R><S><K><G><V><Q><P><K><D><A><M><R><S><L><K><R><R><L><E><N><K><N><P><N><I><Q><I><A><T><L><K><L><T><D><T><C><V><K><N><G><G><T><H><F><L><A><E><I><A><S><R><E><F><M><D><N><L><V><S><L><L><K><A><E><G><V><P><L><N><S><S... | Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.<BOP> | Q5BBK9 |
B0RYY8 | TTCA_XANCB | tRNA 2-thiocytidine biosynthesis protein TtcA | Xanthomonas | <M><T><A><V><L><P><L><P><L><P><L><A><D><P><A><P><R><T><P><R><L><Q><R><E><P><L><R><L><A><K><R><L><R><H><A><V><G><Q><A><I><A><D><F><G><M><I><A><P><G><D><K><V><M><V><C><L><S><G><G><K><D><S><Y><T><L><L><D><M><L><L><Q><L><Q><R><S><A><P><V><P><F><T><L><V><A><V><N><L><D><Q><K><Q><P><D><F><P><A><D><V><L><P><T><Y><L><R><A><Q><Q... | Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.<BOP> | B0RYY8 |
Q7NFD4 | UVRC_GLOVI | Excinuclease ABC subunit C | Gloeobacter | <M><P><N><L><I><A><D><P><E><R><L><K><E><R><L><E><L><L><P><T><S><A><G><V><Y><L><M><R><D><E><A><G><E><I><L><Y><V><G><K><A><K><N><L><R><N><R><V><R><S><Y><F><Q><P><G><H><D><H><S><P><R><I><A><I><M><V><G><K><V><H><D><F><E><L><I><L><T><D><T><E><A><E><A><L><V><L><E><D><N><L><I><K><T><H><K><P><R><Y><N><V><L><L><K><D><D><K><Q><Y... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | Q7NFD4 |
B6JCL3 | UPPP_AFIC5 | Undecaprenyl pyrophosphate phosphatase | Afipia | <M><L><F><D><L><F><K><A><L><V><L><G><I><V><E><G><V><T><E><F><L><P><V><S><S><T><G><H><I><L><L><A><E><R><I><F><D><L><D><Q><D><N><F><W><K><T><F><A><V><L><I><Q><L><G><A><I><L><A><I><L><A><I><Y><F><Q><R><L><W><R><V><A><T><H><M><F><T><D><P><A><A><R><R><F><V><I><G><V><L><V><A><F><L><P><A><V><I><L><G><L><I><F><G><T><F><I><K><E... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | B6JCL3 |
Q6SJR1 | TAF4_ARATH | TBP-associated factor 4 | Arabidopsis | <M><D><L><S><I><V><K><L><L><E><E><D><E><E><V><D><S><K><H><S><E><D><D><L><Q><M><F><Q><D><S><L><I><R><D><I><E><G><S><N><L><K><S><I><N><N><T><T><G><N><E><S><E><K><P><Q><P><R><Y><M><K><L><Q><K><M><S><S><K><E><T><P><W><V><E><K><T><V><D><P><V><N><H><N><L><R><L><A><R><V><T><D><L><L><R><T><V><V><D><H><Q><P><G><K><K><T><H><C><L... | TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.<BOP> | Q6SJR1 |
O26024 | Y1491_HELPY | Putative phosphate permease HP_1491 | Helicobacter | <M><E><I><K><N><I><K><E><F><E><K><A><S><K><K><L><Q><K><D><T><L><K><I><A><L><A><L><L><F><L><I><G><A><A><L><L><A><L><I><F><G><Q><A><N><S><K><G><L><L><L><I><F><A><A><V><I><G><G><Y><M><A><M><N><I><G><A><N><D><V><S><N><N><V><G><P><A><V><G><S><K><A><I><S><M><G><G><A><I><L><I><A><A><I><C><E><M><L><G><A><I><I><A><G><G><E><V><V... | Potential transporter for phosphate.<BOP> | O26024 |
P31058 | YADC_ECOLI | Uncharacterized fimbrial-like protein YadC | Escherichia | <M><K><T><I><F><R><Y><I><L><F><L><A><L><Y><S><C><C><N><T><V><S><A><Y><T><S><F><I><V><G><N><N><A><G><V><D><N><Y><R><G><P><S><T><A><A><Q><M><T><F><N><Y><T><S><T><A><S><N><L><V><F><Y><K><P><T><Q><L><G><P><T><G><V><K><M><Y><W><S><Y><L><D><T><G><T><G><G><G><I><L><Y><C><N><T><S><G><R><A><N><P><G><P><I><T><I><E><N><A><M><V><Y... | Part of the yadCKLM-htrE-yadVN fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches.<BOP> | P31058 |
A7A047 | TVP38_YEAS7 | TLG2-vesicle protein of 38 kDa | Saccharomyces | <M><S><Q><S><Y><E><A><G><N><A><N><M><G><Q><G><E><D><D><E><F><D><G><Y><F><E><D><F><D><N><D><I><M><P><N><S><N><N><G><Q><R><V><G><T><N><A><G><L><S><F><N><D><E><V><N><V><N><D><D><D><F><L><D><I><Y><N><M><S><P><R><E><R><L><M><H><N><I><R><K><N><V><Q><K><L><Q><F><Y><F><Y><S><L><R><L><W><Q><Q><I><I><I><V><L><L><G><I><M><L><M><I... | Golgi membrane protein involved in vesicular trafficking and spindle migration.<BOP> | A7A047 |
O58762 | TRET_PYRHO | Trehalose-synthesizing glycosyltransferase | Pyrococcus | <M><M><Y><E><V><K><E><F><S><S><G><K><R><K><L><E><D><Y><K><S><I><I><G><E><E><E><V><S><K><I><Q><E><K><A><E><K><L><K><G><R><S><F><V><H><V><N><S><T><S><F><G><G><G><V><A><E><I><L><H><S><L><V><P><L><L><R><S><I><G><I><E><A><R><W><F><V><I><E><G><P><T><E><F><F><N><V><T><K><T><F><H><N><A><L><Q><G><N><E><S><L><K><L><T><E><E><M><K... | Synthesizes trehalose from ADP-, UDP- or GDP-glucose and glucose.<BOP> | O58762 |
Q9JJD0 | THA11_MOUSE | Ronin | Mus | <M><P><G><F><T><C><C><V><P><G><C><Y><N><N><S><H><R><D><K><A><L><H><F><Y><T><F><P><K><D><A><E><L><R><R><L><W><L><K><N><V><S><R><A><G><V><S><G><C><F><S><T><F><Q><P><T><T><G><H><R><L><C><S><V><H><F><Q><G><G><R><K><T><Y><T><V><R><V><P><T><I><F><P><L><R><G><V><N><E><R><K><V><A><R><R><P><A><G><A><A><A><A><R><R><R><Q><Q><Q><Q... | Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.<BOP> | Q9JJD0 |
P70901 | VLP12_BORHE | Variable large protein 12 | Borrelia | <M><R><K><R><I><S><A><I><I><M><T><L><F><M><V><L><A><S><C><S><N><Q><L><E><A><E><K><L><A><A><E><S><K><N><T><F><F><D><S><L><V><K><I><G><Q><G><F><Q><D><I><F><G><I><F><G><N><A><I><G><D><A><L><G><F><N><A><V><K><S><D><D><K><R><S><K><V><G><E><H><F><E><G><V><G><K><G><L><K><D><T><K><I><K><L><D><E><L><L><K><E><V><T><A><A><P><H><A... | The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.<BOP> | P70901 |
Q29VN1 | TPS3_MAIZE | Probable terpene synthase 3, chloroplastic | Zea | <M><Y><S><L><P><G><A><T><M><S><A><A><P><A><R><V><I><S><S><S><S><S><S><S><F><V><E><P><L><L><L><A><A><A><S><S><A><A><A><N><S><H><H><Q><V><R><Q><R><G><H><L><V><R><T><L><A><A><S><S><S><S><N><T><L><L><R><S><D><F><D><L><Q><E><G><L><T><T><D><V><K><R><M><L><R><Q><R><Q><K><K><S><G><G><G><R><E><M><L><V><T><I><D><N><L><K><R><L><C... | Probable terpene synthase.<BOP> | Q29VN1 |
Q757R0 | VAC8_ASHGO | Vacuolar protein 8 | Eremothecium | <M><G><G><C><C><S><C><L><K><E><S><Q><D><D><A><T><V><L><P><I><A><E><N><E><R><E><A><V><T><S><L><L><G><Y><L><E><D><K><D><N><Y><D><F><Y><S><G><G><P><L><K><A><L><T><T><L><V><Y><S><D><N><L><N><L><Q><R><S><A><A><L><A><F><A><E><I><T><E><K><Y><V><R><P><V><D><R><E><V><L><E><P><I><L><I><L><L><Q><S><H><D><P><Q><I><Q><I><A><A><C><A... | Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.<BOP> | Q757R0 |
Q6BQJ1 | TVP38_DEBHA | Golgi apparatus membrane protein TVP38 | Debaryomyces | <M><P><R><L><P><S><S><S><D><P><F><Q><G><H><N><E><L><P><Q><S><N><N><F><M><S><R><T><N><S><I><I><Q><D><K><L><F><L><V><R><N><V><G><Q><Q><T><L><D><W><Y><Q><S><Q><P><L><W><K><R><T><L><L><Q><V><L><F><V><F><N><A><I><V><V><V><L><I><M><I><F><H><K><S><I><I><Q><A><I><V><V><I><S><D><K><W><H><G><L><K><F><G><Q><G><L><L><F><T><L><V><F... | Golgi membrane protein involved in vesicular trafficking and spindle migration.<BOP> | Q6BQJ1 |
A1WUY5 | UPPP_HALHL | Undecaprenyl pyrophosphate phosphatase | Halorhodospira | <M><A><L><W><I><A><V><L><L><G><V><V><Q><G><I><F><M><F><L><P><V><S><S><T><A><H><M><V><L><L><E><H><W><L><I><G><R><D><H><P><M><P><A><P><E><S><A><E><M><I><L><F><N><L><V><V><H><V><G><T><L><V><S><I><V><V><V><F><A><P><S><L><L><R><F><T><R><Y><S><L><R><D><A><Y><G><W><A><R><A><G><R><F><Q><G><P><P><L><Y><A><R><L><F><L><L><G><M><L... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | A1WUY5 |
Q6ANL3 | UBIE_DESPS | Demethylmenaquinone methyltransferase | Desulfotalea | <M><R><A><Q><S><C><S><L><F><L><E><M><K><C><R><E><E><F><V><L><S><K><G><P><G><V><E><K><M><F><D><A><I><A><G><R><Y><D><L><M><N><K><V><M><T><M><G><Q><D><Q><R><W><R><R><F><V><V><A><K><A><G><D><P><G><A><G><Q><V><L><D><L><A><T><G><T><G><D><I><A><A><L><M><H><R><S><Y><P><R><A><Q><V><T><G><G><D><F><S><R><N><M><L><E><E><A><K><K><R... | Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).<BOP> | Q6ANL3 |
P25040 | TSR4_YEAST | 20S rRNA accumulation protein 4 | Saccharomyces | <M><S><K><I><E><E><L><P><P><S><D><T><D><D><H><S><Y><S><S><K><P><G><D><V><F><L><A><F><V><D><A><P><V><K><E><T><D><D><I><L><V><E><D><S><F><I><G><G><E><P><K><W><L><H><P><D><S><E><P><P><A><E><L><L><K><C><G><A><C><K><S><A><D><N><M><K><L><L><L><Q><A><F><S><P><L><D><D><E><Q><M><S><A><I><Q><Q><R><L><G><I><N><N><M><S><Y><I><N><P... | Required for processing of the 20S pre-rRNA at site D to generate mature 18S rRNA.<BOP> | P25040 |
Q1BV59 | TYPH_BURCA | TdRPase | Burkholderia cepacia complex | <M><F><L><P><Q><E><F><I><R><R><K><R><D><G><Q><P><L><D><R><D><D><M><A><A><F><V><R><G><V><T><D><G><S><V><T><E><G><Q><V><A><A><F><A><M><A><V><Y><F><N><D><L><S><T><D><E><R><V><A><L><T><L><A><Q><R><D><S><G><D><V><L><D><W><R><A><L><D><L><G><G><P><V><I><D><K><H><S><T><G><G><V><G><D><V><V><S><L><M><L><G><P><M><V><A><A><C><G><G... | The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.<BOP> | Q1BV59 |
A0R2W4 | ZFPP_MYCS2 | Z-isoprenyl diphosphate synthase | Mycolicibacterium | <M><D><I><I><P><P><R><L><K><E><P><A><Y><R><I><Y><E><M><R><L><R><H><E><L><V><R><S><K><A><Q><L><P><R><H><I><A><V><L><C><D><G><N><R><R><W><A><R><D><A><G><Y><D><D><V><S><I><G><Y><R><K><G><A><A><K><I><A><E><M><L><R><W><C><Q><A><A><G><I><E><M><A><T><I><Y><L><L><S><T><E><N><L><Q><R><D><P><D><E><L><T><A><L><I><E><I><I><T><D><V... | Catalyzes the condensation of only one isopentenyl pyrophosphate (IPP) unit in the cis configuration to E-geranyl diphosphate (E-GPP) generating the 15 carbon product (2Z,6E)-farnesyl diphosphate (Z-FPP or EZ-FPP). Z-FPP is the precursor of decaprenyl diphosphate, which has a central role in the biosynthesis of the myc... | A0R2W4 |
P53378 | TBG_YEAST | Gamma-tubulin | Saccharomyces | <M><G><G><E><I><I><T><L><Q><A><G><Q><C><G><N><H><V><G><K><F><L><W><S><Q><L><A><K><E><H><A><I><G><T><D><G><L><S><Q><L><P><D><S><S><T><E><R><D><D><D><T><K><P><F><F><R><E><N><S><R><N><K><F><T><P><R><A><I><M><M><D><S><E><P><S><V><I><A><D><V><E><N><T><F><R><G><F><F><D><P><R><N><T><W><V><A><S><D><G><A><S><A><G><N><S><W><A><N... | Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. TUB4 is an important spindle pole body component that organizes both cytopl... | P53378 |
Q0HHM8 | TOLB_SHESM | Tol-Pal system protein TolB | Shewanella | <M><K><I><L><A><K><W><L><A><L><A><V><L><L><C><T><M><P><A><K><A><A><L><D><I><V><I><T><E><G><V><D><A><A><R><P><I><A><V><M><P><F><Q><W><Q><G><A><G><A><P><P><Q><A><I><A><D><V><V><M><S><D><L><I><R><S><G><T><F><K><P><L><D><E><L><G><L><P><Q><R><G><I><G><A><L><A><Q><F><D><A><S><A><W><A><N><V><G><A><E><A><V><V><V><G><S><V><K><P... | Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP> | Q0HHM8 |
Q88NN6 | URODH_PSEPK | Hexuronate dehydrogenase | Pseudomonas | <M><T><T><T><P><F><N><R><L><L><L><T><G><A><A><G><G><L><G><K><V><L><R><E><R><L><K><G><Y><A><E><V><L><R><L><S><D><I><S><P><M><A><P><A><A><G><P><H><E><E><V><I><T><C><D><L><A><D><K><A><A><V><H><T><L><V><E><G><V><D><A><I><I><H><F><G><G><V><S><T><E><H><A><F><E><E><I><L><G><P><N><I><C><G><V><F><H><V><Y><E><A><A><R><K><H><G><V... | Catalyzes the oxidation of beta-D-galacturonate and beta-D-glucuronate to galactarate and D-glucarate, respectively.<BOP> | Q88NN6 |
O84030 | TRMD_CHLTR | tRNA [GM37] methyltransferase | Chlamydia | <M><E><I><D><I><L><S><L><F><P><D><Y><F><A><S><P><L><Q><A><T><I><L><G><R><A><I><K><Q><G><A><L><S><V><R><S><R><D><I><R><E><F><G><L><G><K><W><K><Q><V><D><D><S><P><Y><N><G><E><G><M><L><L><M><A><E><P><V><V><Q><A><I><R><S><I><R><R><K><K><S><K><V><I><Y><L><S><P><Q><G><Q><L><L><S><A><K><K><S><R><E><L><A><S><C><S><H><L><V><L><L... | Specifically methylates guanosine-37 in various tRNAs.<BOP> | O84030 |
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