accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 2.3k | function stringlengths 11 1.34k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q17ZL5 | Y048_HELAH | Nucleoid-associated protein Hac_0048 | Helicobacter | <M><D><F><S><Q><L><S><G><L><L><D><G><V><K><K><E><F><S><Q><L><E><E><K><N><K><D><T><I><Y><T><S><K><S><G><G><G><M><V><S><V><S><F><N><G><V><G><E><L><V><D><L><Q><I><D><D><S><L><L><E><D><K><E><A><M><Q><I><Y><L><M><S><A><L><N><D><G><Y><K><S><V><E><E><N><R><K><N><L><A><F><S><M><L><G><N><F><A><K><L> | Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP> | Q17ZL5 |
Q6FYF1 | TSAD_BARQU | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Bartonella | <M><R><L><L><G><I><E><T><S><C><D><E><T><A><A><A><V><I><E><H><N><I><E><G><N><S><Q><I><L><S><N><I><V><W><S><Q><T><D><N><H><A><P><Y><G><G><V><V><P><E><I><A><A><R><A><H><V><E><I><L><D><D><L><I><L><K><A><L><T><D><A><H><T><K><L><K><D><I><D><A><I><A><V><T><S><G><P><G><L><I><G><G><L><L><V><G><V><M><S><A><K><A><L><S><L><A><T><G... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q6FYF1 |
Q0SX94 | ULAR_SHIF8 | HTH-type transcriptional regulator UlaR | Shigella | <M><T><E><A><Q><R><H><Q><I><L><L><E><M><L><A><Q><L><G><F><V><T><V><E><K><V><V><E><R><L><G><I><S><P><A><T><A><R><R><D><I><N><K><L><G><E><S><G><K><L><K><K><V><R><N><G><A><E><A><I><T><Q><Q><R><P><R><W><T><P><M><N><L><H><Q><A><Q><N><H><D><E><K><V><R><I><A><K><A><A><S><Q><L><V><N><P><G><E><S><V><V><I><N><C><G><S><T><A><F><L... | Represses ulaG and the ulaABCDEF operon.<BOP> | Q0SX94 |
Q7VQU0 | UBIA_BLOFL | 4-HB polyprenyltransferase | Candidatus Blochmannia | <M><Y><K><R><C><I><G><F><I><K><L><M><R><V><H><Q><P><V><G><F><F><L><L><L><W><P><T><L><W><A><L><W><I><T><N><R><G><I><P><D><F><I><V><L><S><L><F><I><V><G><V><M><C><M><R><S><A><G><C><V><I><N><D><Y><I><D><Y><D><I><D><M><C><V><Q><R><T><I><R><R><P><I><V><I><G><S><V><K><K><Q><E><A><L><W><V><F><F><I><L><I><L><I><A><L><I><V><V><C... | Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-... | Q7VQU0 |
Q9Z964 | TRMD_CHLPN | tRNA [GM37] methyltransferase | Chlamydia | <M><K><I><D><I><L><S><L><F><P><G><Y><F><D><G><P><L><Q><T><S><I><L><G><R><A><I><K><Q><R><L><L><D><V><Q><L><T><N><L><R><D><F><G><L><G><K><W><K><Q><V><D><D><T><P><F><S><G><G><G><M><L><L><M><A><E><P><V><T><S><A><I><R><S><V><R><K><E><N><S><K><V><I><Y><L><S><P><Q><G><A><L><L><T><A><E><K><S><R><E><L><A><A><A><S><H><L><I><L><L... | Specifically methylates guanosine-37 in various tRNAs.<BOP> | Q9Z964 |
P47370 | THIO_MYCGE | Thioredoxin | Mycoplasma | <M><V><T><E><I><R><S><L><K><Q><L><E><E><I><F><S><A><K><K><N><V><I><V><D><F><W><A><A><W><C><G><P><C><K><L><T><S><P><E><F><Q><K><A><A><D><E><F><S><D><A><Q><F><V><K><V><N><V><D><D><H><T><D><I><A><A><A><Y><N><I><T><S><L><P><T><I><V><V><F><E><N><G><V><E><K><K><R><A><I><G><F><M><P><K><T><K><I><I><D><L><F><N><N> | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.<BOP> | P47370 |
A1CEK1 | VPS27_ASPCL | Vacuolar protein sorting-associated protein 27 | Aspergillus subgen. Fumigati | <M><A><G><W><F><S><S><S><S><P><L><D><E><Q><V><E><R><A><T><S><S><S><L><E><D><I><A><L><N><L><E><I><S><D><L><I><R><S><K><S><V><Q><P><K><E><A><M><R><S><L><K><R><R><L><E><N><R><N><P><N><V><Q><I><A><T><L><K><L><T><D><T><C><V><K><N><G><G><T><H><F><L><A><E><I><A><S><R><E><Y><L><D><N><M><V><S><L><L><T><A><E><G><A><P><L><N><S><D... | Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.<BOP> | A1CEK1 |
P05823 | TNR0_ECOLX | Transposon Tn2501 resolvase | Escherichia | <M><S><R><V><F><A><Y><C><R><V><S><T><L><E><Q><T><T><E><N><Q><R><R><E><I><E><A><A><G><F><A><I><R><P><Q><R><L><I><E><E><H><I><S><G><S><V><A><A><S><E><R><P><G><F><I><R><L><L><D><R><M><E><N><G><D><V><L><I><V><T><K><L><D><R><L><G><R><N><A><M><D><I><R><K><T><V><E><Q><L><A><S><S><D><I><R><V><H><C><L><A><L><G><G><V><D><L><T><S... | Resolvase catalyzes the resolution (a site-specific recombination) of the cointegrated replicon to yield the final transposition products.<BOP> | P05823 |
Q12NB8 | THIG_SHEDO | Thiazole synthase | Shewanella | <M><F><T><L><A><D><H><T><F><S><S><R><L><L><T><G><T><G><K><F><T><N><S><H><T><M><L><A><S><I><V><A><S><E><S><Q><I><V><T><L><A><M><K><R><I><D><L><K><L><G><Q><D><D><I><L><T><P><L><L><A><Q><G><L><T><L><L><P><N><T><S><G><A><R><N><A><K><E><A><I><F><A><A><E><L><A><R><D><L><L><D><T><H><W><L><K><L><E><I><H><P><D><P><K><Y><L><M><P... | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP> | Q12NB8 |
Q8FBI6 | TATC_ECOL6 | Sec-independent protein translocase protein TatC | Escherichia | <M><S><V><E><D><T><Q><P><L><I><T><H><L><I><E><L><R><K><R><L><L><N><C><I><I><S><V><I><V><I><F><L><C><L><V><Y><F><A><N><D><I><Y><H><L><V><S><A><P><L><I><K><Q><L><P><Q><G><S><T><M><I><A><T><D><V><A><S><P><F><F><T><P><I><K><L><T><F><M><V><S><L><I><L><S><A><P><V><I><L><Y><Q><V><W><A><F><I><A><P><A><L><Y><K><H><E><R><R><L><V... | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.<BOP> | Q8FBI6 |
Q8FAJ3 | ULAA_ECOL6 | Ascorbate-specific permease IIC component UlaA | Escherichia | <M><E><I><L><Y><N><I><F><T><V><F><F><N><Q><V><M><T><N><A><P><L><L><L><G><I><V><T><C><L><G><Y><I><L><L><R><K><S><V><S><V><I><I><K><G><T><I><K><T><I><I><G><F><M><L><L><Q><A><G><S><G><I><L><T><S><T><F><K><P><V><V><A><K><M><S><E><V><Y><G><I><N><G><A><I><S><D><T><Y><A><S><M><M><A><T><I><E><R><M><G><D><A><Y><S><W><V><G><Y><A... | The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.<BOP... | Q8FAJ3 |
A8F821 | THIC_PSELT | null | Pseudothermotoga | <M><T><Q><M><E><I><A><Q><K><G><T><S><S><E><E><M><K><R><V><A><E><Y><E><E><M><N><L><E><V><I><R><Q><K><L><A><Y><G><K><A><V><L><P><K><N><K><L><H><K><I><E><K><P><M><I><V><G><E><G><F><T><V><K><V><N><A><N><I><G><T><S><Q><A><F><F><S><L><E><E><E><K><E><K><A><R><V><A><I><E><Y><G><A><D><S><L><M><V><L><S><T><W><G><D><L><K><E><I><R... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | A8F821 |
P34710 | UNC6_CAEEL | Uncoordinated protein 6 | Caenorhabditis | <M><I><T><S><V><L><R><Y><V><L><A><L><Y><F><C><M><G><I><A><H><G><A><Y><F><S><Q><F><S><M><R><A><P><D><H><D><P><C><H><D><H><T><G><R><P><V><R><C><V><P><E><F><I><N><A><A><F><G><K><P><V><I><A><S><D><T><C><G><T><N><R><P><D><K><Y><C><T><V><K><E><G><P><D><G><I><I><R><E><Q><C><D><T><C><D><A><R><N><H><F><Q><S><H><P><A><S><L><L><T... | Component of an extracellular matrix cue that guides dorsoventral migrations on the epidermis . Required for the guidance of pioneer axons and migrating cells along the body wall . In particular, it is required for the guidance of axons from neurons, including SubL neurons and AIY interneurons, into the nerve ring . Du... | P34710 |
V9QFH8 | TXA2_STEGR | Latrodectin-2 | Steatoda | <M><F><K><L><I><C><I><V><F><I><A><T><I><L><S><I><T><S><A><A><D><N><E><D><E><L><T><I><E><D><F><L><S><Y><E><C><N><E><S><M><D><I><E><E><L><K><E><K><D><K><V><C><S><R><C><A><N><L><H><K><T><Q><S><V><I><E><R><C><R><L><N><C><F><T><S><E><Y><F><K><N><C><E><D><N><L><Q><A><K><E><E><E><P><E><E><E><T><L> | May increase the toxicity of alpha-latrotoxin and/or other venom components. Is non-toxic to mice and to the cockroach Periplaneta americana.<BOP> | V9QFH8 |
Q6C705 | TRM82_YARLI | Transfer RNA methyltransferase 82 | Yarrowia | <M><K><H><P><Y><H><I><V><S><L><S><P><D><G><K><T><M><Y><A><A><A><A><R><Q><V><D><R><I><C><L><E><T><G><E><C><K><S><T><V><V><E><E><S><A><T><R><T><T><T><K><T><G><D><K><P><A><A><A><K><R><T><K><Y><L><P><T><S><V><S><H><V><R><S><L><Q><L><S><K><G><G><K><Y><L><L><A><T><T><D><E><T><K><S><L><V><L><L><D><P><T><T><L><E><V><I><K><K><V... | Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.<BOP> | Q6C705 |
Q81XH4 | YIDC1_BACAN | Membrane protein YidC 1 | Bacillus cereus group | <M><L><K><S><Y><R><A><V><L><V><S><L><S><L><L><L><V><F><V><L><S><G><C><S><N><A><T><P><I><D><A><H><S><T><G><I><W><D><H><Y><F><V><Y><P><I><S><F><M><I><Q><F><V><A><H><H><I><P><G><A><S><F><G><I><A><I><I><I><M><T><L><V><I><R><S><A><M><I><P><L><A><V><S><Q><Y><R><S><Q><A><K><M><K><K><M><Q><P><E><L><Q><K><L><K><Q><K><Y><G><D><V... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.<BOP> | Q81XH4 |
A1A1N2 | TPIS_BIFAA | Triose-phosphate isomerase | Bifidobacterium | <M><G><P><K><R><I><P><L><V><A><G><N><W><K><M><N><F><D><H><L><E><A><T><Y><F><V><Q><Q><L><A><W><N><L><R><A><I><H><F><D><Y><K><R><C><E><I><A><L><M><P><S><F><T><S><L><R><S><V><Q><V><A><V><E><S><D><N><L><K><I><R><Y><G><A><Q><A><V><S><V><T><S><Q><G><A><F><T><G><D><V><S><A><D><M><I><A><H><L><G><C><S><Y><V><I><V><G><H><S><E><R... | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP> | A1A1N2 |
A5DH87 | TVP38_PICGU | Golgi apparatus membrane protein TVP38 | Meyerozyma | <M><P><R><L><H><S><A><S><E><P><P><A><T><G><F><F><A><R><V><R><N><E><L><G><N><R><T><E><G><L><H><Q><I><N><N><Q><A><L><D><W><Y><R><S><Q><S><Q><I><R><Q><I><L><I><Q><I><G><G><V><V><A><I><V><I><G><V><L><V><L><I><F><H><K><Y><L><I><E><L><L><V><I><I><S><D><D><W><A><K><L><P><G><G><R><L><I><L><F><L><L><V><F><F><V><G><F><P><P><L><I... | Golgi membrane protein involved in vesicular trafficking and spindle migration.<BOP> | A5DH87 |
C5BAT7 | ZAPA_EDWI9 | Z ring-associated protein ZapA | Edwardsiella | <M><S><A><Q><P><V><D><I><Q><I><F><G><R><A><L><R><V><N><C><P><P><E><Q><L><D><A><L><N><Q><A><A><E><D><L><N><Q><R><L><Q><D><L><K><V><R><T><R><V><T><N><T><E><Q><L><V><F><I><A><A><L><N><V><C><H><E><L><A><Q><E><R><L><K><T><R><D><Y><A><A><N><M><E><Q><R><I><R><M><L><Q><Q><T><I><E><Q><A><L><L><E><Q><G><R><I><T><E><R><P><G><T><S... | Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.<BOP> | C5BAT7 |
O57486 | TDT_AMBME | Terminal deoxynucleotidyltransferase | Ambystoma | <M><Y><A><F><P><T><T><R><I><A><P><R><R><K><Q><P><K><C><I><K><P><P><K><C><T><S><K><Y><D><I><K><F><K><D><I><A><I><Y><I><L><E><R><K><M><G><A><S><R><R><Y><F><L><M><E><L><A><R><K><K><G><F><R><V><E><P><D><L><S><E><Y><V><T><H><V><V><S><E><K><N><S><G><A><E><V><L><E><W><L><Q><A><K><K><A><G><S><I><P><N><V><A><I><L><D><I><S><W><F... | Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the mat... | O57486 |
B2UW67 | UREE_HELPS | Urease accessory protein UreE | Helicobacter | <M><I><I><E><R><L><I><G><N><L><R><D><L><N><P><L><D><F><S><V><D><Y><V><D><L><E><W><F><E><T><R><K><K><I><A><R><F><K><T><R><Q><G><K><D><I><A><I><R><L><K><D><A><P><K><L><G><L><S><Q><G><D><I><L><F><K><E><E><K><E><I><I><A><V><N><I><L><D><S><E><V><I><H><I><Q><A><K><S><V><A><E><V><A><K><I><C><Y><E><I><G><N><R><H><A><A><L><Y><Y... | Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.<BOP> | B2UW67 |
A4XYV5 | THIE_PSEMY | Thiamine-phosphate pyrophosphorylase | Pseudomonas | <M><T><A><A><L><R><G><L><Y><A><I><T><D><T><P><L><L><A><G><G><K><L><L><P><Y><A><E><A><A><L><I><G><G><A><R><L><L><Q><Y><R><D><K><S><G><D><A><V><R><R><L><D><E><A><Q><A><L><A><E><L><C><Q><R><H><G><A><T><L><I><I><N><D><D><L><E><L><A><A><H><L><G><V><G><L><H><L><G><Q><T><D><G><S><L><A><A><A><R><A><R><L><G><A><D><V><V><I><G><G... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | A4XYV5 |
B4R966 | YQGF_PHEZH | Putative pre-16S rRNA nuclease | Phenylobacterium | <M><A><V><V><D><L><I><D><L><P><A><I><A><P><P><N><T><P><L><V><G><L><D><L><G><E><K><T><I><G><V><A><V><S><D><A><T><R><M><V><A><S><P><L><G><L><I><R><K><T><K><F><T><D><D><A><K><A><L><F><K><L><M><E><S><R><R><A><S><G><I><V><I><G><L><P><V><N><M><D><G><T><E><G><T><R><C><Q><S><N><R><A><F><A><R><N><L><L><R><L><R><E><D><L><P><I><A... | Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP> | B4R966 |
Q64P45 | TRMB_BACFR | tRNA(m7G46)-methyltransferase | Bacteroides | <M><G><K><N><K><L><E><K><F><A><D><M><A><S><Y><P><H><V><F><E><Y><P><Y><S><A><V><D><N><V><P><F><D><M><K><G><K><W><H><K><E><F><F><K><N><D><N><P><I><V><L><E><L><G><C><G><R><G><E><Y><T><V><G><L><G><R><M><F><P><D><K><N><F><I><A><V><D><I><K><G><A><R><M><W><T><G><A><T><E><S><L><Q><A><G><M><K><N><V><A><F><L><R><T><N><I><E><I><I... | Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP> | Q64P45 |
Q6MTM6 | TMFO1_MYCMS | Folate-dependent tRNA(M-5-U54)-methyltransferase 1 | Mycoplasma | <M><K><T><I><R><I><I><G><A><G><L><S><G><C><E><A><A><Y><Y><L><L><K><K><G><Y><F><V><E><L><Y><E><I><K><T><I><K><K><N><P><I><Q><H><Y><D><Y><F><C><E><L><A><Y><S><D><S><F><R><S><T><D><L><N><T><S><V><G><T><L><K><K><E><L><E><L><L><D><S><L><I><I><K><A><A><K><Y><A><S><I><N><Q><N><N><E><L><V><V><N><R><I><E><F><S><K><Y><I><T><N><Y... | Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.<BOP> | Q6MTM6 |
Q92GI1 | YBEY_RICCN | Endoribonuclease YbeY | spotted fever group | <M><I><N><V><E><I><V><R><N><Y><N><K><W><R><E><H><K><Q><I><N><K><S><L><I><K><K><I><T><Q><N><I><L><L><R><F><D><N><F><S><K><I><K><Q><F><E><L><S><I><L><L><T><N><A><A><E><I><L><T><L><N><K><Q><F><R><N><I><E><K><A><T><N><V><L><S><F><P><S><N><E><L><N><W><Q><D><L><Y><S><K><L><E><F><L><G><D><S><D><Y><M><H><L><G><D><I><A><F><C><Y... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q92GI1 |
Q5L5L8 | TRMD_CHLAB | tRNA [GM37] methyltransferase | Chlamydia | <M><K><I><D><I><L><S><L><F><P><E><Y><F><D><S><P><L><R><S><S><I><L><G><R><A><I><K><R><G><L><L><D><I><Q><S><R><D><I><R><E><F><G><L><G><K><W><K><Q><V><D><D><A><P><F><N><H><D><G><M><L><L><M><A><E><P><V><V><K><A><I><R><H><V><K><R><S><D><S><K><V><V><Y><L><S><P><Q><G><Q><L><L><T><A><K><K><S><R><E><L><A><Q><C><S><H><L><I><F><L... | Specifically methylates guanosine-37 in various tRNAs.<BOP> | Q5L5L8 |
Q9HSG5 | TRUD_HALSA | tRNA-uridine isomerase D | Halobacterium | <M><R><E><A><H><P><I><E><R><A><V><G><M><A><Y><Y><A><S><D><S><D><G><T><G><G><R><L><R><D><S><P><A><D><F><R><V><R><E><L><E><A><F><D><T><Q><P><A><D><A><P><T><G><D><Y><P><W><L><V><V><R><A><T><L><H><E><W><D><T><N><D><F><A><R><E><L><A><N><T><V><G><M><S><R><E><R><V><R><W><A><G><T><K><D><R><H><A><V><T><T><Q><L><F><A><V><R><D><L... | Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP> | Q9HSG5 |
Q9FPH3 | THA2_ARATH | Threonine aldolase 2 | Arabidopsis | <M><V><T><P><T><T><I><R><T><V><D><L><R><S><D><T><V><T><K><P><T><E><S><M><R><S><A><M><A><N><A><E><V><D><D><D><V><L><G><N><D><P><T><A><L><R><L><E><K><E><V><A><E><I><A><G><K><E><A><A><M><F><V><P><S><G><T><M><G><N><L><I><S><V><L><V><H><C><D><E><R><G><S><E><V><I><L><G><D><D><S><H><I><H><I><Y><E><N><G><G><V><S><S><L><G><G><V... | Threonine aldolase involved in threonine degradation to glycine. May play a role in the removal of L-allo-threonine.<BOP> | Q9FPH3 |
B3EE09 | THIC_CHLL2 | Thiamine biosynthesis protein ThiC | Chlorobium | <M><N><T><F><S><D><N><I><F><C><P><E><H><R><M><Y><G><N><A><S><K><K><T><H><T><K><G><C><I><H><P><I><E><V><G><M><R><T><L><S><L><T><K><T><Y><T><C><R><G><I><E><F><S><S><I><P><L><Y><D><T><S><G><P><Y><S><D><P><S><V><I><I><N><P><E><K><G><L><N><P><L><R><D><K><W><K><F><N><S><E><N><T><E><P><V><S><E><Q><G><N><E><T><A><A><A><R><V><P... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | B3EE09 |
A0AJ83 | TRPD_LISW6 | Anthranilate phosphoribosyltransferase | Listeria | <M><E><S><L><L><Q><K><V><Y><D><Q><E><N><L><T><K><A><E><M><N><I><L><A><T><E><I><F><E><G><R><L><S><K><T><K><M><A><A><F><L><M><A><L><K><V><K><G><E><T><A><E><E><M><A><G><I><A><E><A><M><Q><E><V><A><I><Q><V><A><F><P><A><G><T><A><M><D><N><C><G><T><G><G><D><K><S><N><S><F><N><I><S><T><T><S><A><F><V><L><A><A><A><G><I><P><V><A><K... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | A0AJ83 |
Q03A83 | TARI_LACP3 | Ribitol-5-phosphate cytidylyltransferase | Lacticaseibacillus | <M><I><T><A><I><V><L><A><G><G><V><G><K><R><M><G><M><E><I><P><K><Q><F><V><M><V><N><E><K><P><I><I><I><Y><T><L><E><S><F><D><R><H><P><K><I><D><Q><V><V><V><V><C><K><Q><G><W><A><D><T><M><W><G><Y><I><R><E><F><G><I><K><K><V><K><W><V><I><S><G><G><S><I><V><Q><K><S><I><N><N><A><V><Q><F><L><S><D><K><C><V><E><D><D><I><V><V><I><H><D... | Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.<BOP> | Q03A83 |
O32125 | YUTF_BACSU | 5'-nucleotidase YutF | Bacillus | <M><K><T><Y><K><G><Y><L><I><D><L><D><G><T><M><Y><N><G><T><E><K><I><E><E><A><C><E><F><V><R><T><L><K><D><R><G><V><P><Y><L><F><V><T><N><N><S><S><R><T><P><K><Q><V><A><D><K><L><V><S><F><D><I><P><A><T><E><E><Q><V><F><T><T><S><M><A><T><A><Q><H><I><A><Q><Q><K><K><D><A><S><V><Y><V><I><G><E><E><G><I><R><Q><A><I><E><E><N><G><L><T... | Catalyzes the hydrolysis of various purine and pyrimidine 5'-nucleotides, showing preference for 5'-nucleoside monophosphates and exhibiting the highest catalytic activity toward 5'-XMP . Shows also a relatively high phosphohydrolase activity toward the nucleotide precursors ribose-5-phosphate (R5P) and 5-phosphoribosy... | O32125 |
B0U620 | UNG_XYLFM | Uracil-DNA glycosylase | Xylella | <M><N><E><Q><G><E><A><I><N><S><S><A><E><S><R><I><Q><L><E><S><S><W><K><A><H><V><G><N><W><L><L><R><P><E><M><R><D><L><S><S><F><L><R><A><R><K><V><A><G><V><S><V><Y><P><P><G><S><Q><I><F><A><A><F><E><A><T><P><F><Q><R><V><K><A><V><I><L><G><Q><D><P><Y><H><G><Q><G><Q><A><H><G><L><C><F><S><V><R><P><G><M><P><L><P><P><S><L><L><N><I... | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.<BOP> | B0U620 |
P60938 | UPPP_GEOSL | Undecaprenyl pyrophosphate phosphatase | Geobacter | <M><D><I><M><H><A><A><V><L><G><I><L><Q><G><L><T><E><I><L><P><I><S><S><S><A><H><L><I><L><V><P><W><L><L><G><W><P><E><S><G><L><T><F><D><V><G><L><H><V><G><T><L><I><A><L><C><V><Y><F><R><R><D><I><A><Y><L><I><S><D><A><I><T><G><L><R><E><G><F><G><S><Q><T><S><R><L><P><F><F><I><I><A><G><T><V><P><A><A><I><A><G><K><T><L><E><K><P><I... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | P60938 |
Q6S9E0 | TTP_SHEEP | Zinc finger protein 36 | Ovis | <M><D><L><A><A><I><Y><K><S><L><L><S><L><S><P><E><L><P><S><D><L><G><E><T><E><S><S><T><S><W><A><S><S><G><P><W><S><L><S><S><S><D><S><S><L><P><E><A><A><A><R><L><P><G><R><S><T><S><L><V><E><G><R><S><C><G><W><V><P><P><P><P><G><F><A><P><L><A><P><R><P><S><S><E><L><S><P><S><P><T><S><P><T><A><T><P><T><T><S><S><R><Y><K><T><E><L><C... | Zinc-finger RNA-binding protein that destabilizes numerous cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as an 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to ... | Q6S9E0 |
A5WDG7 | TRPA_PSYWF | Tryptophan synthase alpha chain | Psychrobacter | <M><T><R><I><E><S><T><F><E><T><L><K><A><Q><N><K><K><A><L><I><P><Y><V><M><A><G><D><P><S><P><N><S><F><V><D><L><L><H><D><L><V><K><H><G><A><D><M><I><E><V><G><L><P><F><S><D><P><M><A><D><G><P><T><V><A><L><A><G><E><R><A><L><A><G><G><T><S><T><H><Q><A><L><A><I><V><K><K><F><R><E><Q><D><S><S><T><P><I><I><L><M><G><Y><L><N><P><I><E... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | A5WDG7 |
Q9KS29 | TTCA_VIBCH | tRNA 2-thiocytidine biosynthesis protein TtcA | Vibrio | <M><T><A><Q><T><Q><E><L><T><K><A><Q><Q><Y><N><F><N><K><L><Q><K><R><I><R><R><N><T><G><Q><A><I><A><D><F><N><M><I><E><D><G><D><R><I><M><V><C><L><S><G><G><K><D><S><F><T><M><L><D><I><L><M><S><L><Q><K><S><A><P><I><S><F><E><L><V><A><V><N><L><D><Q><K><Q><P><G><F><P><E><H><V><L><P><E><Y><L><E><S><L><G><V><E><Y><K><I><V><E><E><D... | Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.<BOP> | Q9KS29 |
B0SB32 | YBEY_LEPBA | Endoribonuclease YbeY | Leptospira | <M><N><P><S><L><S><V><F><T><H><W><N><D><E><S><N><Q><S><E><I><F><S><D><P><V><I><S><N><C><E><K><I><L><R><F><L><A><P><E><F><L><H><S><L><E><L><S><I><Y><L><V><N><D><S><L><M><A><E><I><N><E><E><R><R><G><K><P><A><T><T><D><V><L><S><F><P><L><Y><S><E><H><P><P><I><P><V><Q><I><L><G><E><V><V><I><S><M><E><T><C><K><K><Q><A><M><E><I><G... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | B0SB32 |
Q5CZA5 | ZN805_HUMAN | Zinc finger protein 805 | Homo | <M><A><M><A><L><T><D><P><A><Q><V><S><V><T><F><D><D><V><A><V><T><F><T><Q><E><E><W><G><Q><L><D><L><A><Q><R><T><L><Y><Q><E><V><M><L><E><N><C><G><L><L><V><S><L><G><C><P><V><P><R><P><E><L><I><Y><H><L><E><H><G><Q><E><P><W><T><R><K><E><D><L><S><Q><G><T><C><P><G><D><K><G><K><P><K><S><T><E><P><T><T><C><E><L><A><L><S><E><G><I><S... | May be involved in transcriptional regulation.<BOP> | Q5CZA5 |
Q0VLN5 | UBID_ALCBS | Polyprenyl p-hydroxybenzoate decarboxylase | Alcanivorax | <M><K><Y><R><D><L><R><D><F><I><S><Q><L><E><Q><L><G><E><L><K><R><I><T><V><P><V><D><P><K><L><E><M><T><E><I><C><D><R><T><L><R><A><G><G><P><A><L><L><F><E><N><P><V><G><F><G><T><P><V><L><G><N><L><F><G><T><E><R><R><V><A><L><G><M><G><R><D><S><V><A><E><L><R><E><L><G><E><L><L><A><F><L><K><E><P><E><P><P><K><G><F><R><D><A><W><E><K... | Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP> | Q0VLN5 |
Q0HE99 | UBIB_SHESM | Ubiquinone biosynthesis protein UbiB | Shewanella | <M><T><L><A><S><I><R><R><G><Y><H><V><I><K><T><L><L><Q><Y><G><L><D><D><V><L><P><P><K><M><T><P><W><Y><F><K><L><A><R><N><S><L><F><W><I><R><N><K><H><K><G><K><S><G><G><E><R><L><K><L><A><M><Q><E><L><G><P><V><Y><I><K><L><G><Q><M><L><S><T><R><R><D><L><L><S><D><E><W><A><N><E><L><A><M><L><Q><D><K><V><P><P><F><D><G><A><L><A><R><Q... | Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.<BOP> | Q0HE99 |
Q0ASJ7 | TRUA_MARMM | tRNA-uridine isomerase I | Maricaulis | <M><P><R><Y><R><I><T><I><E><Y><D><G><R><P><F><S><G><W><Q><R><Q><D><N><A><P><S><V><Q><E><S><L><E><R><A><A><E><K><L><D><G><A><P><V><L><V><Y><G><A><G><R><T><D><S><G><V><H><A><L><A><Q><V><A><H><L><D><L><A><K><D><L><S><T><D><K><V><R><D><A><I><N><Y><H><L><K><P><D><P><V><A><V><I><E><A><A><R><V><S><D><D><F><H><A><R><F><S><A><T... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | Q0ASJ7 |
Q68W09 | YBEY_RICTY | Endoribonuclease YbeY | typhus group | <M><I><N><V><E><I><V><R><N><Y><N><K><W><R><E><H><R><K><I><N><K><G><L><I><K><K><I><T><Q><N><V><L><V><R><F><D><H><F><D><K><I><K><Q><F><E><L><S><I><L><L><T><N><T><A><E><I><L><T><L><N><Q><Q><F><R><S><I><E><K><A><T><N><V><L><S><F><P><N><N><E><L><N><W><H><N><L><Y><S><K><L><E><F><L><Y><Y><S><D><Y><M><H><L><G><D><I><A><F><C><Y... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q68W09 |
A5V9W7 | TRPA_RHIWR | Tryptophan synthase alpha chain | Rhizorhabdus | <M><T><R><L><A><E><T><F><A><R><T><R><A><E><G><R><A><A><L><V><T><F><V><T><G><G><D><P><T><P><G><D><M><G><P><I><L><D><A><L><V><A><G><G><A><D><V><I><E><L><G><M><P><F><T><D><P><M><A><D><G><P><A><I><Q><R><A><N><L><R><A><L><G><A><G><T><T><T><A><D><L><L><A><I><A><A><A><F><R><Q><R><H><P><S><V><P><L><V><L><M><G><Y><A><N><P><M><V... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | A5V9W7 |
C6DYS1 | YIDC_GEOSM | Membrane protein YidC | unclassified Geobacter | <M><E><K><R><L><I><I><A><V><V><L><S><I><G><V><L><Y><A><Y><S><F><I><F><P><T><P><K><P><V><P><T><P><G><G><K><Q><A><A><M><S><S><A><T><A><P><A><P><S><V><A><A><L><P><I><A><G><T><T><P><V><A><A><P><A><P><Q><A><G><Q><A><P><A><V><A><K><D><V><T><V><D><T><D><L><Y><T><A><V><F><S><T><Q><G><G><G><L><K><K><F><V><L><K><K><Y><K><E><T><A... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb... | C6DYS1 |
Q4QPI7 | UVRC_HAEI8 | Excinuclease ABC subunit C | Haemophilus | <M><F><D><A><K><K><F><L><A><D><V><S><H><E><P><G><V><Y><R><M><Y><D><D><K><D><Q><V><I><Y><V><G><K><A><K><D><L><K><K><R><L><S><S><Y><F><R><K><N><L><S><S><K><K><T><E><A><L><V><A><S><I><H><H><I><D><T><M><L><T><S><S><E><T><E><A><L><L><L><E><H><N><F><I><K><L><Y><Q><P><R><Y><N><V><L><L><R><D><D><K><S><Y><P><F><I><L><L><T><K><E... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | Q4QPI7 |
Q755J9 | VPS27_ASHGO | Vacuolar protein sorting-associated protein 27 | Eremothecium | <M><N><T><E><I><Q><T><V><A><A><L><G><E><C><I><Q><R><A><T><S><E><S><I><P><N><G><E><I><D><L><A><L><A><L><D><V><S><D><A><V><R><S><R><R><L><G><A><R><D><S><M><R><A><L><K><K><R><V><L><Q><T><K><S><N><P><N><T><Q><L><A><A><W><R><L><V><E><V><C><V><K><N><G><G><T><H><F><L><K><E><V><C><S><R><E><F><M><D><C><M><E><H><V><A><A><Q><E><K... | Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.<BOP> | Q755J9 |
P45125 | UVRB_HAEIN | Excinuclease ABC subunit B | Haemophilus | <M><S><E><K><I><N><T><K><P><F><I><L><H><S><D><F><R><P><S><G><D><Q><P><Q><A><I><E><K><L><A><E><N><L><T><D><G><L><A><H><Q><T><L><L><G><V><T><G><S><G><K><T><F><T><I><A><N><V><I><A><Q><L><N><R><P><A><M><L><L><A><P><N><K><T><L><A><A><Q><L><Y><A><E><M><K><A><F><F><P><E><N><A><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | P45125 |
Q97CP8 | VATD_THEVO | V-ATPase subunit D | Thermoplasma | <M><E><I><R><P><T><R><I><E><L><I><R><T><R><R><R><I><K><L><A><R><K><G><L><D><L><L><K><M><K><R><S><A><L><I><Y><E><F><L><Q><I><S><R><T><I><R><G><M><R><E><N><L><R><R><E><V><E><D><A><L><N><T><I><R><T><A><E><I><L><E><G><Q><V><A><L><E><R><I><A><N><M><S><S><D><S><T><I><N><V><D><S><R><N><V><M><G><V><V><I><P><T><L><N><L><T><Y><N... | Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP> | Q97CP8 |
B9DM01 | XPT_STACT | Xanthine phosphoribosyltransferase | Staphylococcus | <M><E><A><L><R><Q><K><V><K><E><D><G><V><V><I><G><E><K><I><L><K><V><D><G><F><L><N><H><Q><I><D><A><Q><L><M><Y><D><I><G><E><T><F><Y><E><Q><F><K><D><Q><K><V><T><K><I><L><T><V><E><A><S><G><I><A><P><A><I><M><V><A><Y><K><F><G><V><P><C><L><F><A><K><K><A><K><P><N><T><L><N><K><G><F><Y><Q><T><D><I><H><S><F><T><K><D><K><T><N><S><V... | Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP> | B9DM01 |
Q9K9G7 | THIZ_HALH5 | Formylaminopyrimidine import ATP-binding protein ThiZ | Halalkalibacterium (ex Joshi et al. 2022) | <M><V><K><E><L><L><T><F><E><E><V><S><F><A><Y><S><S><S><S><P><V><I><E><R><L><S><F><T><V><F><E><N><E><I><V><A><I><L><A><K><S><G><S><G><K><S><T><L><F><R><L><I><T><R><L><E><S><P><D><Q><G><T><I><V><C><H><A><Q><G><K><I><G><Y><M><P><Q><Q><D><L><L><L><P><W><L><T><I><L><E><N><V><S><L><P><L><E><I><Q><G><K><D><K><K><E><A><K><I><I... | Participates in a thiamine pyrimidine salvage pathway as part of the ABC transporter complex ThiXYZ involved in the import of thiamine degradation products such as the formylaminopyrimidine N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine (FAMP). Is likely responsible for energy coupling to the transport system.<BOP> | Q9K9G7 |
Q5HR05 | Y390_STAEQ | Putative lipid kinase SERP0390 | Staphylococcus | <M><K><Q><P><Y><N><H><G><V><L><F><Y><H><E><H><S><G><L><K><D><I><H><N><G><I><G><E><V><A><K><S><L><S><S><M><C><K><H><L><S><L><Q><L><S><E><N><K><G><D><I><I><K><Y><C><K><S><I><K><N><E><N><Y><S><S><D><V><D><V><L><F><I><L><G><G><D><G><T><L><N><E><L><V><N><G><V><M><Q><Y><Q><L><N><L><P><I><G><V><I><P><G><G><T><F><N><D><F><T><K... | May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG).<BOP> | Q5HR05 |
B0CA92 | YCF3_ACAM1 | Photosystem I assembly protein Ycf3 | Acaryochloris | <M><P><S><D><N><F><I><D><K><A><F><S><A><M><S><D><V><V><M><K><V><I><P><T><D><Q><K><S><K><D><A><F><K><Y><Y><R><S><G><M><A><A><Q><V><D><G><N><Y><A><K><A><L><G><N><Y><T><E><A><L><A><L><E><E><D><P><F><D><K><S><Y><I><L><Y><N><M><G><L><I><F><A><N><N><G><D><H><E><K><A><L><D><Y><Y><H><Q><S><L><E><L><N><P><N><L><V><Q><A><L><Y><N... | Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits.<BOP> | B0CA92 |
A1L167 | U2QL1_HUMAN | E2Q-like ubiquitin-conjugating enzyme 1 | Homo | <M><K><E><L><Q><D><I><A><R><L><S><D><R><F><I><S><V><E><L><V><D><E><S><L><F><D><W><N><V><K><L><H><Q><V><D><K><D><S><V><L><W><Q><D><M><K><E><T><N><T><E><F><I><L><L><N><L><T><F><P><D><N><F><P><F><S><P><P><F><M><R><V><L><S><P><R><L><E><N><G><Y><V><L><D><G><G><A><I><C><M><E><L><L><T><P><R><G><W><S><S><A><Y><T><V><E><A><V><M... | Probable E2 ubiquitin-protein ligase that catalyzes the covalent attachment of ubiquitin to target proteins. May facilitate the monoubiquitination and degradation of MTOR and CCNE1 through interaction with FBXW7.<BOP> | A1L167 |
C5BYK3 | TILS_BEUC1 | tRNA(Ile)-lysidine synthetase | Beutenbergia | <M><S><G><P><H><P><S><V><A><A><A><R><N><A><V><R><A><L><L><A><E><L><E><P><A><R><G><V><L><V><A><C><S><G><G><A><D><S><L><A><L><A><A><A><T><A><F><V><A><P><R><A><G><R><A><A><G><A><V><V><V><D><H><A><L><Q><A><G><S><A><E><V><A><A><R><A><A><D><Q><C><R><G><L><G><L><E><A><R><V><V><R><V><D><V><D><I><A><L><G><G><P><E><G><A><A><R><A... | Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP> | C5BYK3 |
P45359 | THLA_CLOAB | CaTHL | Clostridium | <M><K><E><V><V><I><A><S><A><V><R><T><A><I><G><S><Y><G><K><S><L><K><D><V><P><A><V><D><L><G><A><T><A><I><K><E><A><V><K><K><A><G><I><K><P><E><D><V><N><E><V><I><L><G><N><V><L><Q><A><G><L><G><Q><N><P><A><R><Q><A><S><F><K><A><G><L><P><V><E><I><P><A><M><T><I><N><K><V><C><G><S><G><L><R><T><V><S><L><A><A><Q><I><I><K><A><G><D><A... | Catalyzes the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA . Involved in solvent production .<BOP> | P45359 |
B7JN72 | THIE_BACC0 | Thiamine-phosphate pyrophosphorylase | Bacillus cereus group | <M><S><R><I><S><K><A><E><M><S><K><L><L><S><V><Y><F><I><M><G><S><N><N><C><T><K><D><P><L><Q><V><L><R><E><A><L><E><G><G><I><T><I><F><Q><F><R><E><K><G><E><G><A><L><T><G><E><E><R><I><C><F><A><K><E><L><Q><A><I><C><K><E><Y><G><V><P><F><I><V><N><D><D><V><E><L><A><L><E><L><D><A><D><G><V><H><V><G><Q><D><D><E><G><I><T><S><V><R><E... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | B7JN72 |
Q4KJA1 | THIC_PSEF5 | Thiamine biosynthesis protein ThiC | Pseudomonas | <M><T><T><K><L><K><N><A><S><N><L><S><E><S><A><Q><V><D><Q><Q><S><V><Q><P><F><T><R><S><Q><K><V><Y><V><Q><G><S><R><P><D><I><R><V><P><M><R><E><I><T><L><D><V><T><P><T><D><F><G><G><E><I><N><A><P><V><T><V><Y><D><T><S><G><P><Y><T><D><P><N><V><V><I><D><V><R><K><G><L><G><D><V><R><S><A><W><I><E><D><R><G><D><T><E><R><L><A><G><L><S... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | Q4KJA1 |
P21798 | TNNC2_BALNU | Troponin C, isoform 2 | Balanus | <M><M><D><E><L><D><K><D><Q><I><A><M><L><K><K><A><F><D><G><F><D><H><E><K><K><G><A><I><N><C><D><V><V><A><T><I><L><R><M><M><G><Q><A><Y><N><A><Q><T><L><K><E><L><I><D><E><V><D><A><D><G><S><G><M><L><E><F><E><E><F><V><T><L><A><A><K><F><I><I><D><D><D><A><E><A><M><A><K><E><L><K><E><A><F><R><L><Y><D><K><A><G><K><G><Y><I><P><T><S... | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.<BOP> | P21798 |
Q8Y832 | TARI_LISMO | Ribitol-5-phosphate cytidylyltransferase | Listeria | <M><I><Y><A><E><I><L><A><G><G><K><G><T><R><M><G><N><V><N><M><P><K><Q><Y><L><P><L><K><G><K><P><I><I><V><H><T><I><E><K><F><I><L><N><D><R><F><E><K><I><I><I><A><T><P><K><D><W><I><N><H><T><Q><D><I><I><K><K><Y><I><F><D><S><R><V><I><V><I><E><G><G><T><D><R><N><E><T><I><M><N><G><I><R><Y><V><E><K><E><F><G><L><N><E><D><D><I><I><V... | Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.<BOP> | Q8Y832 |
Q73H71 | TSAD_WOLPM | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | unclassified Wolbachia | <M><K><T><I><L><A><V><E><T><S><C><D><E><T><A><V><A><I><V><N><S><D><K><Q><V><L><A><H><E><I><L><S><Q><A><E><H><K><K><R><G><G><V><I><P><E><I><A><S><R><A><H><M><E><H><L><S><G><L><I><K><S><A><V><E><K><S><N><L><N><F><C><D><L><N><A><I><A><A><T><S><G><P><G><L><I><G><G><L><I><V><G><T><M><M><A><K><A><I><A><H><V><A><Q><K><P><F><I... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q73H71 |
Q3KKY7 | TIG_CHLTA | PPIase | Chlamydia | <M><S><S><R><D><F><S><N><D><L><F><S><I><N><I><E><E><N><A><G><C><V><V><S><A><K><V><Q><A><N><P><L><V><T><Q><K><C><H><K><E><A><L><K><T><V><K><K><N><V><V><L><P><G><F><R><K><G><K><A><P><D><N><I><V><E><S><R><Y><S><T><Q><V><E><Q><E><L><R><R><L><F><L><R><A><S><F><E><A><L><S><Q><M><C><D><R><K><P><L><S><P><K><A><V><R><S><S><A><I... | Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP> | Q3KKY7 |
Q67ES1 | TR113_RAT | Taste receptor type 2 member 30 | Rattus | <M><V><A><V><L><Q><S><T><F><A><I><I><F><S><M><E><F><I><V><G><T><L><G><N><G><F><I><I><L><M><T><C><I><D><W><V><R><R><R><K><I><S><L><V><D><Q><I><L><T><A><L><A><I><T><R><I><T><L><I><L><L><V><F><I><D><W><W><V><S><V><L><F><P><A><L><H><E><T><G><K><I><L><R><M><Y><F><I><S><W><T><V><I><N><H><C><N><L><W><L><T><A><S><L><S><I><I><Y... | Putative taste receptor which may play a role in the perception of bitterness.<BOP> | Q67ES1 |
Q9PG67 | TSAD_XYLFA | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Xylella | <M><K><I><I><G><I><E><S><S><C><D><E><T><G><V><A><V><Y><D><T><A><L><S><G><F><A><A><L><R><A><H><S><V><Y><S><Q><V><A><L><H><A><E><Y><G><G><V><V><P><E><L><A><S><R><D><H><V><R><K><L><L><P><L><L><R><Q><T><L><A><E><A><K><L><S><V><E><E><L><D><G><V><A><Y><T><A><G><P><G><L><V><G><A><L><L><V><G><A><G><V><A><R><A><L><A><W><A><L><E... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q9PG67 |
B5F7D6 | YDIB_SALA4 | NAD-dependent shikimate 5-dehydrogenase | Salmonella | <M><D><V><T><A><K><Y><E><L><I><G><L><M><A><Y><P><I><R><H><S><L><S><P><E><M><Q><N><K><A><L><E><K><A><G><L><P><Y><T><Y><M><A><F><E><V><D><N><T><T><F><A><S><A><I><E><G><L><K><A><L><K><M><R><G><T><G><V><S><M><P><N><K><Q><L><A><C><E><Y><V><D><E><L><T><P><A><A><K><L><V><G><A><I><N><T><I><V><N><D><D><G><Y><L><R><G><Y><N><T><D... | The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD o... | B5F7D6 |
A4WB03 | TRPA_ENT38 | Tryptophan synthase alpha chain | Enterobacter | <M><E><R><Y><D><N><A><F><T><E><L><K><A><R><K><E><G><A><F><V><P><F><V><T><L><G><D><P><G><P><E><Q><S><L><K><I><I><D><T><L><I><A><A><G><A><D><A><L><E><L><G><I><P><F><S><D><P><L><A><D><G><P><T><I><Q><S><A><T><L><R><A><F><A><S><G><V><T><P><T><Q><C><F><E><M><L><A><T><V><R><Q><K><Y><P><T><I><P><I><G><L><L><M><Y><A><N><L><V><F... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | A4WB03 |
A7H4T0 | THIC_CAMJD | Thiamine biosynthesis protein ThiC | Campylobacter | <M><K><T><Q><M><N><Y><A><K><E><G><V><F><T><K><E><M><Q><I><V><A><Q><K><E><N><L><S><K><D><F><L><L><E><N><I><A><C><G><K><I><I><I><P><A><N><I><N><H><K><S><L><D><P><N><G><I><G><F><G><L><R><T><K><V><N><V><N><L><G><V><S><N><D><C><V><D><Y><S><E><E><M><K><K><V><E><L><A><H><K><F><G><I><E><A><I><M><D><L><S><N><Y><G><K><T><S><R><F... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | A7H4T0 |
P18726 | ZG5A_XENLA | Gastrula zinc finger protein XlCGF51.1A | Xenopus | <T><G><E><K><P><F><S><C><S><D><C><G><A><R><F><T><Y><R><S><L><L><R><R><H><N><K><I><H><A><E><G><K><S><L><I><C><S><E><C><G><K><P><F><T><S><E><S><A><L><T><A><H><Q><R><S><H><G><G><E><K><P><F><S><C><T><D><C><E><K><C><F><A><Q><R><M><H><L><I><E><H><Q><R><T><H><T><G><E><K><P><F><S><C><T><V><C><G><E><M><F><T><Y><R><A><Q><F><S><K... | May be involved in transcriptional regulation.<BOP> | P18726 |
Q255B1 | TRMD_CHLFF | tRNA [GM37] methyltransferase | Chlamydia | <M><E><I><D><I><L><S><L><F><P><D><Y><F><D><S><P><L><R><S><S><I><L><G><R><A><I><K><N><G><L><L><K><I><Q><S><R><D><I><R><E><F><G><L><G><K><W><K><Q><V><D><D><A><P><F><N><N><D><G><M><L><L><M><A><E><P><V><V><Q><A><I><R><Y><V><K><R><R><E><S><R><V><I><H><L><S><P><Q><G><V><P><L><T><A><Q><K><S><R><E><L><A><K><C><S><H><L><I><F><L... | Specifically methylates guanosine-37 in various tRNAs.<BOP> | Q255B1 |
C5CQK5 | TATA_VARPS | Sec-independent protein translocase protein TatA | Variovorax | <M><G><S><F><S><I><W><H><W><L><I><V><L><L><V><V><V><M><I><F><G><T><K><K><L><R><N><M><G><S><D><L><G><G><A><V><K><G><F><K><D><G><M><K><D><G><S><T><T><D><A><P><A><A><S><S><A><P><A><A><Q><V><T><G><Q><P><A><N><S><D><K><S><T><I><D><V><E><A><R><Q><K><S> | Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP> | C5CQK5 |
Q9RPX3 | YU58_BRUSU | Type IV secretion system putative outer membrane lipoprotein BRA0058/BS1330_II0058 | Brucella | <M><R><T><L><V><M><V><A><C><A><V><S><L><A><A><C><S><S><P><P><K><P><P><T><V><S><G><R><H><R><I><P><I><N><S><P><A><A><Q><E><E><L><R><L><Q><V><F><P><Q><E><P><T><A><Q><A><T><M><W><P><A><R><P><P><K><Q><T><V><S><V><Y><F><P><Q><D><V><T><V><F><R><P><T><S><A><Q><I><N><Q><L><H><T><L><L><W><P><V><P><K><H><I><N><V><R><G><L><T><D><N... | The VirB system could be required for the establishment of the replication niche in the host.<BOP> | Q9RPX3 |
Q5FC64 | ZDHCS_CAEEL | Defective spermatogenesis protein 10 | Caenorhabditis | <M><S><W><Y><S><K><I><Y><V><A><V><R><E><Y><R><A><K><H><K><I><T><G><W><I><L><T><R><C><L><N><V><L><L><F><I><Q><L><I><L><L><W><W><S><L><Y><M><Y><V><T><V><T><I><G><Y><Y><V><Q><S><T><I><Q><A><T><I><Y><L><I><V><G><S><F><L><F><V><M><S><M><W><S><L><A><K><T><L><F><T><R><V><G><R><V><P><E><R><Y><R><P><S><K><E><L><E><D><R><L><K><A... | Involved in spermatogenesis, specifically in the morphogenesis of fibrous body-membranous organelles (FB-MO), which are Golgi-derived organelles used for transporting sperm-specific components, in spermatocytes and in their localization into budding spermatids . Required for the proper formation of spermatids and sperm... | Q5FC64 |
Q02115 | TAGU_BACSU | Membrane-bound protein LytR | Bacillus | <M><R><N><E><R><R><K><K><K><K><T><L><L><L><T><I><L><T><I><I><G><L><L><V><L><G><T><G><G><Y><A><Y><Y><L><W><H><K><A><A><S><T><V><A><S><I><H><E><S><I><D><K><S><K><K><R><D><K><E><V><S><I><N><K><K><D><P><F><S><V><L><I><M><G><V><D><E><R><D><G><D><K><G><R><A><D><T><L><I><Y><M><T><V><N><P><K><T><N><T><T><D><M><V><S><I><P><R><D... | May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).<BOP> | Q02115 |
P76499 | YFCP_ECOLI | Uncharacterized fimbrial-like protein YfcP | Escherichia | <M><N><K><S><M><I><Q><S><G><G><Y><V><L><L><A><G><L><I><L><A><M><S><S><T><L><F><A><A><D><N><N><L><H><F><S><G><N><L><L><S><K><S><C><A><L><V><V><D><G><Q><Y><L><A><E><V><R><F><P><T><V><S><R><Q><D><L><N><V><A><G><Q><S><A><R><V><P><V><V><F><K><L><K><D><C><K><G><P><A><G><Y><N><V><K><V><T><L><T><G><V><E><D><S><E><Q><P><G><F><L... | Part of the yfcOPQRSUV fimbrial operon. Could contribute to adhesion to various surfaces in specific environmental niches. Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim genes.<BOP> | P76499 |
A9KYL6 | UBIB_SHEB9 | Ubiquinone biosynthesis protein UbiB | Shewanella | <M><T><L><A><S><I><R><R><G><Y><H><V><I><K><T><L><L><Q><Y><G><L><D><D><V><L><P><P><K><M><T><P><W><Y><F><K><L><A><R><N><S><L><F><W><I><R><N><K><H><K><N><K><P><G><G><E><R><L><K><L><A><M><Q><E><L><G><P><V><Y><I><K><L><G><Q><M><L><S><T><R><R><D><L><L><S><D><E><W><A><S><E><L><A><M><L><Q><D><K><V><P><P><F><D><G><A><L><A><R><Q... | Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.<BOP> | A9KYL6 |
P84017 | TX24_PHONI | Neurotoxin PNTx24A0C3 | Phoneutria | <V><F><C><R><F><N><G><Q><Q><C><T><S><D><G><Q><C><C><Y><G><K><C><R><T><A><F><M><G><K><I><C><M> | Acts as a neurotoxin.<BOP> | P84017 |
B2KIQ4 | WDR76_RHIFE | WD repeat-containing protein 76 | Rhinolophus | <M><S><G><S><C><A><A><A><E><E><K><E><G><S><R><Q><R><L><Q><M><K><V><N><E><Y><K><E><N><Q><N><M><S><S><V><S><L><R><S><I><Q><K><T><V><L><E><K><T><V><K><V><C><L><V><P><F><S><L><S><N><Y><K><S><G><Q><F><K><L><P><K><S><L><L><D><K><N><S><K><N><E><V><A><C><K><K><Y><K><K><T><E><I><K><K><A><C><T><R><I><L><T><S><K><M><E><A><T><A><S... | Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.<BOP> | B2KIQ4 |
Q182C6 | YBEY_CLOD6 | Endoribonuclease YbeY | Clostridioides | <M><D><L><I><L><D><D><R><Q><D><K><L><E><V><S><E><E><L><I><E><K><I><K><D><I><I><I><E><C><L><D><Y><E><G><Y><D><D><N><Y><E><V><S><L><S><F><V><D><N><K><E><I><H><E><L><N><R><E><Y><R><G><V><D><R><V><T><D><V><L><S><F><P><L><L><S><D><D><F><E><D><V><E><L><E><E><E><S><L><G><D><I><V><V><S><L><E><R><A><L><E><Q><S><I><E><Y><N><H><S... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | Q182C6 |
Q9HM64 | VATB_THEAC | V-ATPase subunit B | Thermoplasma | <M><P><K><L><A><Y><K><S><V><S><Q><I><S><G><P><L><L><F><V><E><N><V><P><N><A><A><Y><N><E><M><V><D><I><E><L><E><N><G><E><T><R><Q><G><Q><V><L><D><T><R><K><G><L><A><I><V><Q><I><F><G><A><T><T><G><I><G><T><Q><G><T><T><V><K><F><R><G><E><T><A><R><L><P><I><S><E><D><M><L><G><R><V><F><N><G><I><G><E><P><I><D><G><G><P><E><I><I><A><K... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.<BOP> | Q9HM64 |
B7LY16 | TRPA_ECO8A | Tryptophan synthase alpha chain | Escherichia | <M><E><R><Y><E><S><L><F><A><Q><L><K><E><R><K><E><G><A><F><V><P><F><V><T><L><G><D><P><G><I><E><Q><S><L><K><I><I><D><T><L><I><E><A><G><A><D><A><L><E><L><G><I><P><F><S><D><P><L><A><D><G><P><T><I><Q><N><A><T><L><R><A><F><A><A><G><V><T><P><A><Q><C><F><E><M><L><A><L><I><R><Q><K><H><P><T><I><P><I><G><L><L><M><Y><A><N><L><V><F... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | B7LY16 |
Q12GB2 | TGT_POLSJ | tRNA-guanine transglycosylase | unclassified Polaromonas | <M><L><E><F><E><V><L><K><T><D><A><R><T><G><E><G><A><N><A><H><P><G><S><H><A><R><R><G><Q><L><T><L><T><H><G><V><V><Q><T><P><I><F><M><P><V><G><T><Y><G><T><V><K><G><V><M><P><Q><S><L><H><E><M><G><A><Q><I><I><L><G><N><T><F><H><L><W><M><R><P><G><L><D><V><M><K><Q><F><G><G><L><H><R><F><E><S><W><D><K><P><I><L><T><D><S><G><G><F><Q... | Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th... | Q12GB2 |
Q1MAQ8 | TSAD_RHIL3 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Rhizobium | <M><V><P><F><L><R><I><L><G><I><E><T><S><C><D><E><T><A><A><A><V><V><E><R><D><A><E><G><H><S><N><V><L><S><D><V><V><L><S><Q><L><D><E><H><S><A><Y><G><G><V><V><P><E><I><A><A><R><A><H><V><E><A><L><D><E><L><I><E><E><A><L><K><R><A><N><V><S><L><N><D><V><D><A><I><A><A><T><S><G><P><G><L><I><G><G><L><L><V><G><L><M><T><G><K><A><I><A... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q1MAQ8 |
A8AKT3 | THIG_CITK8 | Thiazole synthase | Citrobacter | <M><L><R><I><A><D><K><T><F><D><S><H><L><F><T><G><T><G><K><F><A><S><S><Q><L><M><V><E><A><I><R><A><S><G><S><Q><L><V><T><L><A><M><K><R><V><D><L><R><Q><H><N><D><A><I><L><A><P><L><I><D><A><G><V><T><L><L><P><N><T><S><G><A><K><T><A><E><E><A><I><F><A><A><Q><L><A><R><E><A><L><G><T><H><W><L><K><L><E><I><H><P><D><A><R><W><L><L><P... | Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP> | A8AKT3 |
Q97LP3 | Y511_CLOAB | Nucleotide-binding protein CA_C0511 | Clostridium | <M><R><F><V><I><V><T><G><L><S><G><A><G><K><T><Q><A><I><R><S><L><E><D><L><G><Y><F><C><I><D><N><L><P><P><A><L><I><P><K><F><A><Q><V><C><Y><E><S><E><S><K><I><N><K><I><A><L><V><I><D><I><R><G><G><E><F><F><D><N><L><F><E><S><L><K><Y><L><K><E><A><G><Y><K><Y><E><I><L><F><L><D><A><D><N><E><V><L><I><K><R><F><K><E><S><R><R><K><H><P... | Displays ATPase and GTPase activities.<BOP> | Q97LP3 |
Q9BXA7 | TSSK1_HUMAN | Serine/threonine-protein kinase 22A | Homo | <M><D><D><A><A><V><L><K><R><R><G><Y><L><L><G><I><N><L><G><E><G><S><Y><A><K><V><K><S><A><Y><S><E><R><L><K><F><N><V><A><I><K><I><I><D><R><K><K><A><P><A><D><F><L><E><K><F><L><P><R><E><I><E><I><L><A><M><L><N><H><C><S><I><I><K><T><Y><E><I><F><E><T><S><H><G><K><V><Y><I><V><M><E><L><A><V><Q><G><D><L><L><E><L><I><K><T><R><G><A... | Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-288' of TSKS. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the f... | Q9BXA7 |
Q8Z996 | TILS_SALTI | tRNA(Ile)-lysidine synthetase | Salmonella | <M><T><T><L><T><L><N><T><S><L><L><S><S><R><R><I><L><A><A><F><S><G><G><L><D><S><T><V><L><L><H><Q><L><V><L><W><R><E><R><H><P><D><V><T><L><R><A><I><H><I><H><H><G><L><S><P><H><A><D><S><W><V><R><H><C><E><T><V><C><E><R><W><Q><V><P><L><V><V><E><R><V><T><L><A><D><N><G><L><G><I><E><A><H><A><R><E><A><R><Y><R><A><F><A><Q><T><L><L... | Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP> | Q8Z996 |
B2U6Y7 | TRPA_RALPJ | Tryptophan synthase alpha chain | Ralstonia | <M><S><R><I><A><Q><T><F><S><Q><L><S><A><Q><G><R><K><G><L><I><P><F><I><T><A><G><D><P><Y><P><E><M><T><V><D><L><M><H><A><L><V><K><G><G><S><N><V><I><E><L><G><V><P><F><S><D><P><M><A><D><G><P><V><I><Q><R><A><S><E><R><A><L><A><K><K><V><G><L><R><T><V><L><E><Y><V><R><A><F><R><A><T><D><L><T><T><P><V><V><L><M><G><Y><A><N><P><I><E... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | B2U6Y7 |
B3DR08 | TILS_BIFLD | tRNA(Ile)-lysidine synthetase | Bifidobacterium | <M><A><Y><S><A><R><L><R><K><A><V><G><A><V><R><T><T><L><S><A><V><E><L><C><D><V><Q><A><P><E><F><A><Q><H><G><D><H><A><V><A><S><D><A><P><L><V><L><V><A><C><S><G><G><R><D><S><M><A><L><A><A><V><S><H><I><V><C><T><S><M><G><V><R><C><G><V><V><I><V><D><H><G><L><Q><E><G><S><E><Q><V><A><G><E><A><A><N><R><C><R><A><L><G><L><G><P><V><I... | Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP> | B3DR08 |
P85800 | VARI_AMBVA | Variegin | Amblyomma | <S><D><Q><G><D><V><A><E><P><K><M><H><K><T><A><P><P><F><D><F><E><A><I><P><E><E><Y><L><D><D><E><S> | Thrombin inhibitor. Does not inhibit other serine proteases.<BOP> | P85800 |
Q9JT57 | TYSY_NEIMA | Thymidylate synthase | Neisseria | <M><K><A><Y><L><D><L><M><R><H><V><L><D><N><G><T><D><K><S><D><R><T><G><T><G><T><R><S><V><F><G><Y><Q><M><R><F><D><L><G><K><G><F><P><L><L><T><T><K><K><L><H><L><R><S><I><I><H><E><L><L><W><F><L><K><G><D><T><N><I><K><Y><L><K><D><N><N><V><S><I><W><D><E><W><A><D><E><N><G><D><L><G><P><V><Y><G><Y><Q><W><R><N><W><P><A><P><D><G><R... | Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell... | Q9JT57 |
Q63EC6 | TRPA_BACCZ | Tryptophan synthase alpha chain | Bacillus cereus group | <M><G><V><E><R><I><Q><A><A><F><E><N><G><K><K><A><F><I><P><Y><V><M><G><G><D><G><G><L><E><I><L><K><E><R><I><R><F><L><D><E><A><G><A><S><I><V><E><I><G><I><P><F><S><D><P><V><A><D><G><P><T><I><Q><R><A><G><K><R><A><L><D><S><G><V><T><V><K><G><I><F><Q><A><L><I><E><A><R><K><E><V><Q><I><P><F><V><L><M><T><Y><L><N><P><V><L><A><F><G... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | Q63EC6 |
Q7VRL0 | TPIS_BLOFL | Triose-phosphate isomerase | Candidatus Blochmannia | <M><K><N><L><S><I><I><A><N><W><K><L><N><G><N><K><N><T><I><T><N><S><L><I><N><L><T><T><Q><L><T><N><I><P><Q><Y><I><K><I><A><I><A><P><P><I><L><Y><I><D><M><V><K><N><H><L><T><S><Y><N><N><K><T><I><E><L><C><S><Q><N><V><D><I><H><L><S><G><A><F><T><G><D><I><S><A><S><M><L><K><D><L><S><V><K><Y><V><L><I><G><H><S><E><R><R><I><Y><H><K... | Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP> | Q7VRL0 |
Q6HLU3 | TRPA_BACHK | Tryptophan synthase alpha chain | Bacillus cereus group | <M><G><V><E><R><I><K><A><A><F><E><N><G><K><K><A><F><I><P><Y><V><M><G><G><D><G><G><L><E><I><L><K><E><R><I><R><F><L><D><E><A><G><A><S><I><V><E><I><G><I><P><F><S><D><P><V><A><D><G><P><T><I><Q><R><A><G><K><R><A><L><D><S><G><V><T><V><K><G><I><F><Q><A><L><I><E><V><R><E><E><V><Q><I><P><F><V><L><M><T><Y><L><N><P><V><L><A><F><G... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | Q6HLU3 |
Q896K7 | VATE1_CLOTE | V-ATPase subunit E 1 | Clostridium | <M><S><R><L><E><N><L><T><S><K><I><I><K><D><S><E><E><K><A><K><I><I><L><D><E><A><K><R><E><E><E><K><I><M><L><G><Q><K><Q><E><G><E><S><I><K><S><K><I><I><E><K><A><Y><L><E><S><K><N><R><K><E><R><I><I><S><N><S><H><L><F><V><R><N><R><K><L><E><A><K><Q><E><V><I><D><K><V><Y><K><E><A><L><N><K><L><A><K><L><N><K><E><E><Y><L><N><F><I><K... | Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP> | Q896K7 |
C5BSX6 | Y3824_TERTT | Nucleotide-binding protein TERTU_3824 | Teredinibacter | <M><R><L><L><I><I><S><G><R><S><G><S><G><K><T><T><A><L><H><L><L><E><D><E><G><Y><T><C><I><D><N><L><P><V><D><L><L><P><A><L><I><E><Q><L><S><T><S><D><R><P><S><P><R><V><A><I><G><I><D><A><R><N><I><N><N><D><L><S><R><L><M><A><M><I><E><V><G><P><L><P><R><E><S><Y><Q><V><I><Y><L><D><S><S><R><E><V><L><L><K><R><Y><S><E><T><R><R><K><H... | Displays ATPase and GTPase activities.<BOP> | C5BSX6 |
Q5WSX6 | TRHO_LEGPL | tRNA hydroxylation protein O | Legionella | <M><K><D><I><I><I><A><S><F><Y><K><F><I><P><L><N><D><F><E><S><L><R><E><P><I><L><T><K><M><H><E><I><G><I><K><G><T><I><I><L><A><H><E><G><V><N><G><G><F><A><G><N><R><E><Q><M><Y><I><F><Y><D><Y><L><R><S><D><S><R><F><A><D><L><H><F><K><E><T><Y><D><N><K><N><P><F><D><K><A><K><V><K><L><R><K><E><I><V><T><M><G><V><Q><K><V><D><P><S><Y... | Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP> | Q5WSX6 |
A6U170 | XERC_STAA2 | Tyrosine recombinase XerC | Staphylococcus | <M><N><H><I><Q><E><A><F><L><N><T><L><K><V><E><R><N><F><S><E><H><T><L><K><S><Y><Q><D><D><L><I><Q><F><N><Q><F><L><E><Q><E><H><L><Q><L><K><T><F><E><Y><R><D><A><R><N><Y><L><S><Y><L><Y><S><N><H><L><K><R><T><S><V><S><R><K><I><S><T><L><R><T><F><Y><E><Y><W><M><T><L><D><E><N><I><I><N><P><F><V><Q><L><V><H><P><K><K><E><K><Y><L><P... | Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plas... | A6U170 |
G3Y423 | YANE_ASPNA | Yanuthone D biosynthesis cluster protein E | Aspergillus subgen. Circumdati | <M><A><P><C><K><P><R><T><F><T><A><G><E><D><P><L><T><K><F><D><G><A><I><S><V><A><T><M><P><R><P><A><D><R><Q><F><L><F><H><G><I><M><R><P><S><R><G><I><Y><A><K><L><V><A><T><G><K><K><P><P><T><H><F><H><P><S><Q><W><E><F><F><R><V><L><R><G><N><L><T><V><D><I><N><G><V><P><V><H><R><T><V><D><D><G><E><M><A><V><P><P><Y><T><H><H><V><I><Y... | Part of the gene cluster that mediates the biosynthesis of yanuthone D, a fungal isoprenoid epoxycyclohexenone that acts as an antibiotic against fungi and bacteria . The first step of the pathway is the synthesis of 6-methylsalicylic acid (6-MSA) by the polyketide synthase yanA . 6-MSA is then converted to m-cresol by... | G3Y423 |
P17795 | VIRB5_AGRFC | Protein virB5 | Agrobacterium tumefaciens complex | <M><K><I><M><Q><L><V><A><A><A><M><A><V><S><L><L><S><V><G><P><A><R><A><Q><F><V><V><S><D><P><A><T><E><A><E><T><L><A><T><A><L><E><T><A><A><N><L><E><Q><T><I><T><M><V><A><M><L><T><S><A><Y><G><V><T><G><L><L><T><S><L><N><Q><K><N><Q><Y><P><S><T><R><D><L><D><T><E><M><F><S><P><R><M><P><M><S><T><T><A><R><A><I><T><T><D><T><D><R><A... | VirB proteins are suggested to act at the bacterial surface and there play an important role in directing T-DNA transfer to plant cells.<BOP> | P17795 |
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