accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
Q1IS40
NUOH2_KORVE
NDH-1 subunit H 2
Candidatus Koribacter
<M><G><S><I><A><L><F><L><L><V><A><L><I><K><V><V><L><V><I><F><V><L><L><T><A><V><A><Y><T><V><W><L><E><R><K><V><V><G><R><M><Q><N><R><W><G><P><T><R><V><G><P><F><G><L><L><Q><P><L><A><D><G><L><K><F><I><L><K><E><D><L><L><P><P><H><V><N><K><P><L><Y><I><L><A><P><M><L><A><V><A><M><A><L><L><S><I><S><I><V><P><F><G><G><T><L><T><I><G...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
Q1IS40
Q8XAA4
RLMN_ECO57
tRNA m2A37 methyltransferase
Escherichia
<M><S><E><Q><L><V><T><P><E><N><V><T><T><K><D><G><K><I><N><L><L><D><L><N><R><Q><Q><M><R><E><F><F><K><D><L><G><E><K><P><F><R><A><D><Q><V><M><K><W><M><Y><H><Y><C><C><D><N><F><D><E><M><T><D><I><N><K><V><L><R><G><K><L><K><E><V><A><E><I><R><A><P><E><V><V><E><E><Q><R><S><S><D><G><T><I><K><W><A><I><A><V><G><D><Q><R><V><E><T><V...
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.<BOP>
Q8XAA4
Q9XB61
CARA_PECCC
Carbapenam-3-carboxylate ligase
Pectobacterium
<M><S><N><S><F><C><V><V><Y><K><G><S><D><T><D><I><N><N><I><Q><R><D><F><D><G><K><G><E><A><L><S><N><G><Y><L><F><I><E><Q><N><G><H><Y><Q><K><C><E><M><E><R><G><T><A><Y><L><I><G><S><L><Y><N><R><T><F><L><I><G><L><A><G><V><W><E><G><E><A><Y><L><A><N><D><A><E><L><L><A><L><L><F><T><R><L><G><A><N><A><L><A><L><A><E><G><D><F><C><F><F...
Involved in the biosynthesis of carbapenam-3-carboxylate, a beta-lactam antibiotic of the carbapenem class. Catalyzes the ATP-dependent formation of (3S,5S)-carbapenam-3-carboxylate from (2S,5S)-5-carboxymethylproline.<BOP>
Q9XB61
Q2LR33
ENO_SYNAS
2-phosphoglycerate dehydratase
Syntrophus
<M><T><E><I><I><E><V><H><A><R><E><I><L><D><S><R><G><N><P><T><V><E><A><E><V><T><L><L><S><G><I><S><G><R><A><S><V><P><S><G><A><S><T><G><E><H><E><M><L><E><L><R><D><G><D><P><K><R><Y><L><G><K><G><V><T><Q><A><V><N><N><V><I><E><K><I><A><P><E><I><V><G><M><D><C><L><N><Q><R><D><I><D><Y><T><M><I><A><L><D><G><T><E><N><K><G><A><L><G...
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP>
Q2LR33
Q0P7U6
BIOB_CAMJE
Biotin synthase
Campylobacter
<M><Q><I><M><L><C><A><I><S><N><I><A><S><G><N><C><S><E><D><C><K><Y><C><T><Q><S><A><H><V><K><T><D><I><Q><K><Y><R><R><K><E><L><S><Q><I><V><L><E><A><K><M><A><K><K><N><E><A><L><G><F><C><L><V><T><A><G><L><G><L><D><D><E><K><L><E><Y><V><C><E><A><A><K><A><V><Q><K><E><V><P><N><L><L><L><I><A><C><N><G><M><A><S><V><E><Q><L><K><E><L...
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.<BOP>
Q0P7U6
Q9X1X7
NADA_THEMA
Quinolinate synthase
Thermotoga
<M><V><D><E><I><L><K><L><K><K><E><K><G><Y><I><I><L><A><H><N><Y><Q><I><P><E><L><Q><D><I><A><D><F><V><G><D><S><L><Q><L><A><R><K><A><M><E><L><S><E><K><K><I><L><F><L><G><V><D><F><M><A><E><L><V><K><I><L><N><P><D><K><K><V><I><V><P><D><R><S><A><T><C><P><M><A><N><R><L><T><P><E><I><I><R><E><Y><R><E><K><F><P><D><A><P><V><V><L><Y...
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.<BOP>
Q9X1X7
Q1R183
ISFD_CHRSD
Isethionate formation reductase
Chromohalobacter
<M><T><D><C><V><F><I><T><G><A><T><S><G><F><G><R><A><A><A><H><R><F><A><A><A><G><W><S><L><V><L><T><G><R><R><L><E><R><L><E><A><L><K><E><E><L><Q><G><R><V><P><V><H><I><I><A><L><D><V><R><D><S><D><V><V><D><A><A><V><A><A><L><P><E><G><F><T><R><V><R><T><L><L><N><N><A><G><L><A><L><A><P><Q><S><A><Q><H><T><D><R><S><D><W><H><T><M><I...
Catalyzes the formation of isethionate from 2-sulfoacetaldehyde in the deaminative pathway of taurine. The enzyme is specific for NADPH; NADH is not a substrate. Responsible for most of the activity observed in taurine-grown cells.<BOP>
Q1R183
C5CGG9
NFI_KOSOT
Deoxyribonuclease V
Kosmotoga
<M><K><I><R><C><L><H><D><W><N><V><S><L><E><E><A><A><D><I><Q><R><T><L><K><G><M><L><S><F><E><F><P><A><K><K><V><S><I><V><A><G><V><D><V><S><F><P><Q><K><N><L><G><L><C><V><I><V><V><M><D><D><T><L><K><V><I><E><S><V><Y><H><T><Q><E><V><H><I><P><Y><V><S><G><F><L><S><F><R><E><G><P><I><F><I><E><T><V><K><K><L><K><I><V><P><D><L><F><F...
DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.<BOP>
C5CGG9
P86318
CYC24_RHOPL
Cytochrome c2
Rhodopseudomonas
<Q><D><A><A><K><G><E><A><L><F><K><Q><C><Q><T><C><H><R><A><D><K><N><M><V><G><P><A><L><A><G><V><V><G><R><K><A><G><T><A><P><G><F><S><Y><S><P><L><N><H><A><A><G><E><A><G><L><V><W><S><Q><E><N><V><V><E><Y><L><A><D><P><N><A><F><L><K><K><F><L><T><D><K><G><Q><A><D><K><A><T><G><S><T><K><M><T><F><K><L><A><N><E><Q><Q><R><K><D><V><A...
Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.<BOP>
P86318
Q0ASQ1
PHNC_MARMM
Phosphonates import ATP-binding protein PhnC
Maricaulis
<M><T><D><A><A><L><A><L><Q><A><E><N><L><R><M><T><F><G><E><T><K><A><L><D><D><V><S><L><S><V><K><P><G><E><M><V><A><L><I><G><P><S><G><S><G><K><S><T><L><L><R><V><A><A><A><L><Q><V><A><D><A><E><S><G><P><V><S><V><L><G><K><T><M><Q><Q><R><G><K><L><S><G><R><V><Q><R><N><R><I><Q><L><G><F><I><F><Q><Q><F><N><L><V><G><R><L><S><L><F><Q...
Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system.<BOP>
Q0ASQ1
Q8R1J3
ZCHC9_MOUSE
Zinc finger CCHC domain-containing protein 9
Mus
<M><T><R><W><A><R><V><T><T><S><N><S><K><R><P><L><S><A><T><S><W><E><D><M><K><K><G><S><V><E><R><A><D><Q><S><L><P><N><R><K><Q><C><Q><S><S><R><L><P><L><R><N><D><S><P><Q><A><K><R><K><K><N><K><K><K><K><E><Y><L><N><E><D><V><N><G><F><M><E><Y><L><K><Q><N><S><Q><V><L><H><N><G><Q><L><I><A><A><D><S><Q><E><V><R><E><E><I><A><V><A><L...
May down-regulate transcription mediated by NF-kappa-B and the serum response element.<BOP>
Q8R1J3
Q2YVZ4
SBI_STAAB
Immunoglobulin-binding protein Sbi
Staphylococcus
<M><K><N><K><Y><I><S><K><L><L><V><G><A><A><T><I><T><L><A><T><M><I><S><N><G><E><A><K><A><S><E><N><T><Q><Q><T><S><T><K><H><Q><T><T><Q><N><N><Y><I><T><D><Q><Q><K><A><F><Y><Q><V><L><H><L><K><G><I><T><E><E><Q><R><N><Q><Y><I><K><T><L><R><E><H><P><E><R><A><Q><E><V><F><S><E><S><L><K><D><S><K><N><P><D><R><R><V><A><Q><Q><N><A><F...
Plays a role in the inhibition of both the innate and adaptive immune responses. Possesses two N-terminal domains that bind the Fc region of IgG and two domains that form a tripartite complex with complement factors C3b and CFH. By recruiting CFH and C3b, the secreted form acts as a potent complement inhibitor of the a...
Q2YVZ4
Q6PCT8
DHSD_RAT
Succinate-ubiquinone reductase membrane anchor subunit
Rattus
<M><A><V><L><L><K><L><G><V><L><C><S><G><Q><G><A><R><A><L><S><L><R><S><R><A><V><R><P><A><F><V><S><A><F><L><Q><D><Q><P><T><P><G><W><R><G><T><Q><H><I><H><L><S><P><S><H><Q><S><G><S><K><A><A><S><L><H><W><T><S><E><R><V><V><S><V><L><L><L><G><L><I><P><A><G><Y><L><N><P><C><S><V><V><D><Y><S><L><A><A><A><L><T><L><H><S><H><W><G><I...
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).<BOP>
Q6PCT8
Q8NMB8
ISPD_CORGL
MEP cytidylyltransferase
Corynebacterium
<M><S><S><T><R><I><P><V><I><A><L><L><A><A><A><G><R><G><T><R><L><G><G><P><I><P><K><A><F><V><T><L><R><E><R><T><L><L><E><R><S><L><Q><A><M><L><T><S><E><S><V><D><E><I><I><I><L><V><S><P><D><M><E><T><Y><A><R><D><L><L><R><K><R><G><L><L><N><D><P><E><G><V><R><V><R><L><V><H><G><G><G><E><R><A><D><S><V><W><A><G><L><Q><A><I><S><L><D...
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
Q8NMB8
Q42191
OXA1_ARATH
Oxidase assembly 1 protein
Arabidopsis
<M><A><F><R><Q><T><L><S><I><R><S><R><L><F><A><R><R><N><Q><P><V><Y><H><I><I><P><R><E><S><D><H><E><R><D><S><F><C><Q><E><T><S><Q><R><S><Y><H><S><F><L><H><Q><R><S><V><N><N><S><D><F><S><K><V><S><G><G><S><L><H><L><P><L><A><P><T><S><G><F><A><F><Y><R><Y><M><S><S><A><P><G><V><G><S><E><K><I><G><V><M><S><D><I><A><E><V><I><T><D><S...
Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for activity and assembly of cytochrome c oxidase.<BOP>
Q42191
Q5QW31
SYP_IDILO
Prolyl-tRNA synthetase
Idiomarina
<M><R><S><S><K><Y><L><L><S><T><L><K><E><T><P><S><D><A><E><I><V><S><H><Q><L><M><L><R><A><G><M><I><R><K><V><A><A><G><L><Y><T><W><T><P><T><G><L><R><V><L><R><K><V><E><N><V><V><R><E><E><M><E><A><I><N><A><L><E><I><L><M><P><M><V><Q><P><A><D><L><W><Q><E><S><G><R><W><D><D><Y><G><P><E><L><L><R><I><K><D><R><N><Q><R><D><F><L><L><G...
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two addit...
Q5QW31
A0B573
GGR_METTP
Geranylgeranyl reductase
Methanothrix
<M><R><C><D><V><V><V><V><G><A><G><P><G><G><S><M><A><A><K><T><A><A><E><K><G><L><K><V><V><L><V><E><K><R><Q><E><I><G><D><P><V><R><C><A><E><G><V><S><K><A><R><L><S><S><M><I><K><P><D><P><K><W><I><A><S><E><V><K><G><A><R><L><Y><A><P><D><G><S><N><V><V><M><S><E><D><K><S><G><D><E><V><G><Y><V><L><E><R><K><I><F><D><R><A><L><A><M><D...
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeran...
A0B573
Q5HB23
EFTS_EHRRW
Elongation factor Ts
Ehrlichia
<M><K><V><D><I><N><A><I><K><E><L><R><D><L><T><G><A><G><V><G><D><C><K><D><A><L><T><S><C><N><G><D><I><E><K><A><K><T><Y><L><R><E><Q><G><I><A><K><A><Y><K><K><S><N><K><D><V><S><D><G><L><V><A><I><C><I><D><G><N><K><G><A><I><L><E><V><N><S><E><T><D><F><V><A><R><N><E><K><F><Q><K><L><V><L><N><L><A><F><L><A><N><Q><Y><G><I><E><N><I...
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.<BOP>
Q5HB23
Q88W75
LSPA_LACPL
Signal peptidase II
Lactiplantibacillus
<M><W><I><Y><L><I><L><M><V><A><L><V><I><I><D><Q><V><I><K><A><A><I><V><S><H><I><A><L><G><A><S><T><S><I><V><T><G><L><L><S><L><T><N><L><H><N><N><G><A><A><W><S><I><L><E><G><K><M><W><F><F><Y><L><I><S><V><I><A><L><I><V><M><G><Y><L><L><W><R><L><R><G><K><W><L><Y><E><V><G><I><S><L><M><I><A><G><T><L><G><N><F><I><D><R><L><R><I><G...
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.<BOP>
Q88W75
Q5M7C7
JAGN1_XENLA
Protein jagunal homolog 1
Xenopus
<M><A><S><R><A><G><P><R><A><T><G><S><D><G><S><D><F><Q><H><R><E><K><V><A><G><H><Y><K><M><S><A><S><L><K><N><E><I><K><K><L><I><Y><A><H><L><I><I><W><M><L><I><A><A><Q><M><C><V><S><H><L><K><L><V><S><K><D><L><V><A><M><P><Y><Q><W><E><Y><P><Y><L><L><S><L><V><P><S><L><F><G><L><F><S><F><P><R><N><N><I><S><Y><L><V><I><S><M><I><S><T...
Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function.<BOP>
Q5M7C7
Q4QLD2
GLRX4_HAEI8
Monothiol glutaredoxin
Haemophilus
<M><E><T><L><D><K><I><K><K><Q><I><S><E><N><P><I><L><I><Y><M><K><G><S><P><K><L><P><S><C><G><F><S><A><R><A><S><E><A><L><M><H><C><K><V><P><F><G><Y><V><D><I><L><Q><H><P><D><I><R><A><E><L><P><T><Y><A><N><W><P><T><F><P><Q><L><W><V><E><G><E><L><I><G><G><C><D><I><I><L><E><M><Y><Q><A><G><E><L><Q><T><L><L><A><E><V><A><A><K><H><A...
Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters.<BOP>
Q4QLD2
B8GTX6
AMPA_THISH
Leucyl aminopeptidase
Thioalkalivibrio
<M><E><F><S><V><K><S><G><N><P><E><K><Q><R><S><A><C><V><V><V><G><V><F><D><R><R><K><L><S><S><A><A><R><V><L><D><K><A><S><G><G><A><L><S><T><I><L><R><R><G><D><M><D><G><E><K><G><Q><T><L><W><L><Y><N><L><P><N><T><L><C><E><R><V><L><L><V><G><C><G><K><E><R><D><F><D><E><P><A><Y><R><S><V><I><A><T><V><A><R><T><V><N><K><S><G><A><V><E...
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.<BOP>
B8GTX6
Q7VFY9
KPRS_HELHP
Phosphoribosyl pyrophosphate synthase
Helicobacter
<M><R><G><F><K><I><F><S><G><S><A><H><T><L><F><S><N><E><V><A><K><C><L><D><I><S><L><S><K><T><T><I><N><R><F><S><D><G><E><I><N><V><Q><I><G><E><S><V><R><G><K><D><I><F><I><I><Q><P><T><C><A><P><A><N><D><H><L><M><E><L><L><I><M><T><D><A><L><K><R><S><G><A><K><N><I><N><A><V><I><P><Y><F><G><Y><A><R><Q><D><R><K><V><V><P><R><V><P><I...
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).<BOP>
Q7VFY9
Q9JLG9
AIPL1_RAT
Aryl-hydrocarbon-interacting protein-like 1
Rattus
<M><D><V><S><L><L><L><N><V><E><G><V><K><K><T><I><L><H><G><G><T><G><E><L><P><N><F><I><T><G><S><R><V><T><F><H><F><R><T><M><K><C><D><E><E><R><T><V><I><D><D><S><K><Q><V><G><Q><P><M><N><I><I><I><G><N><M><F><K><L><E><V><W><E><T><L><L><T><S><M><R><L><G><E><V><A><E><F><W><C><D><T><I><H><T><G><V><Y><P><M><L><S><R><S><L><R><Q><V...
May be important in protein trafficking and/or protein folding and stabilization.<BOP>
Q9JLG9
E0D7H6
FC2_PHOAM
Fusicoccin A biosynthetic gene clusters protein 2
Diaporthe
<M><G><S><T><A><E><D><F><V><I><K><P><M><K><G><E><H><G><F><G><A><E><I><Y><G><L><D><V><N><N><I><T><D><E><Q><V><D><R><L><R><D><T><I><Q><R><Y><L><L><V><V><L><K><H><Q><H><D><E><T><P><Q><K><N><W><E><L><L><N><R><L><S><P><D><A><P><K><F><T><P><E><E><W><A><L><M><Y><N><P><D><P><Q><G><A><G><I><L><P><K><L><G><Y><L><V><L><P><G><T><E...
Alpha-ketoglutarate-dependent dioxygenase; part of the 2 gene clusters that mediate the biosynthesis of fusicoccins, diterpene glucosides that display phytohormone-like activity and function as potent activators of plasma membrane H(+)-ATPases in plants by modifying 14-3-3 proteins and cause the plant disease constrict...
E0D7H6
F8S1I0
C7BL2_LACSA
Cytochrome P450 71BL2
Lactuca
<M><E><P><L><T><I><V><S><L><A><V><A><S><F><L><L><F><A><F><W><A><L><S><P><K><T><S><K><N><L><P><P><G><P><P><K><L><P><I><I><G><N><I><H><Q><L><K><S><P><T><P><H><R><V><L><R><N><L><A><K><K><Y><G><P><I><M><H><L><Q><L><G><Q><V><S><T><V><V><V><S><T><P><R><L><A><R><E><I><M><K><T><N><D><I><S><F><A><D><R><P><T><T><T><T><S><Q><I><F...
Involved in the biosynthesis of germacrene-derived sesquiterpene lactones . Component of the parthenolide biosynthetic pathway; parthenolide and conjugates are promising anti-cancer drugs highly active against colon cancer cells . Hydroxylates germacrene A acid to 6-alpha-hydroxy-germacrne A acid, a precursor of sesqui...
F8S1I0
A1AXS4
DCUP_RUTMC
Uroporphyrinogen decarboxylase
Candidatus Ruthia
<M><L><F><D><Y><I><N><A><L><L><K><K><P><T><L><R><T><P><I><W><V><M><R><Q><A><G><R><Y><L><P><E><Y><R><E><T><R><I><K><A><G><D><F><L><T><L><C><K><S><P><E><L><A><C><E><V><T><M><Q><P><I><D><R><F><D><L><D><A><A><I><L><F><S><D><I><L><T><I><P><D><A><M><G><L><G><L><Y><F><L><E><G><E><G><P><K><F><S><N><P><L><N><T><L><S><S><I><E><Q...
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.<BOP>
A1AXS4
Q9C8Y4
ATA15_ARATH
Protein ARABIDOPSIS A-FIFTEEN
Arabidopsis
<M><A><L><N><V><S><K><V><V><P><N><S><P><I><L><V><K><S><V><N><A><S><R><S><R><R><V><L><L><A><Y><V><H><H><P><L><A><A><N><K><G><S><S><I><E><E><L><K><Q><G><L><C><C><T><K><T><V><T><F><V><S><S><R><R><C><S><T><L><C><F><V><G><K><S><Q><D><T><E><T><N><S><Q><V><V><Q><K><E><G><E><K><Q><V><M><P><R><R><K><S><S><N><S><S><Q><L><L><V><E...
Involved in modulation of redox homeostasis to regulate leaf senescence mediated by age and stress factors during plant development. Its function is dependent of EIN2, a central factor of ethylene signaling.<BOP>
Q9C8Y4
C6E4Q6
RL4_GEOSM
50S ribosomal protein L4
unclassified Geobacter
<M><A><K><L><D><V><F><D><I><K><K><A><K><V><G><E><I><E><L><D><D><A><V><F><N><D><D><V><R><E><Y><L><I><H><E><A><V><K><I><Q><L><A><N><R><R><Q><G><T><V><A><V><K><N><R><A><L><V><A><G><S><G><K><K><P><F><K><Q><K><G><T><G><Q><A><R><Q><G><C><R><R><A><P><Q><Y><P><G><G><G><V><A><F><G><P><Q><P><K><D><Y><N><L><S><M><N><K><K><A><R><K...
Forms part of the polypeptide exit tunnel.<BOP>
C6E4Q6
B7KNU8
RL25_METC4
General stress protein CTC
Methylorubrum
<M><S><A><T><K><T><L><E><A><V><A><R><D><R><V><G><K><G><A><A><R><A><V><R><R><Q><G><Q><I><P><A><V><I><Y><G><G><N><Q><A><P><Q><A><I><A><I><D><L><I><R><A><R><T><L><I><Y><A><G><G><F><K><T><T><V><F><E><I><D><A><G><G><K><K><T><R><A><I><P><R><D><Y><Q><L><D><P><V><S><G><V><P><L><H><V><D><F><L><R><V><V><A><G><Q><T><V><T><V><D><V...
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.<BOP>
B7KNU8
Q9XED8
ARFI_ARATH
Auxin response factor 9
Arabidopsis
<M><A><N><R><G><G><E><Y><L><Y><D><E><L><W><K><L><C><A><G><P><L><V><D><V><P><Q><A><Q><E><R><V><Y><Y><F><P><Q><G><H><M><E><Q><L><E><A><S><T><Q><Q><V><D><L><N><T><M><K><P><L><F><V><L><P><P><K><I><L><C><N><V><M><N><V><S><L><Q><A><E><K><D><T><D><E><V><Y><A><Q><I><T><L><I><P><V><G><T><E><V><D><E><P><M><S><P><D><P><S><P><P><E...
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin...
Q9XED8
Q87SZ2
RS13_VIBPA
30S ribosomal protein S13
Vibrio
<M><A><R><I><A><G><I><N><I><P><D><Q><K><H><A><V><I><A><L><T><A><I><Y><G><I><G><K><T><R><S><Q><A><I><L><A><E><V><G><I><A><E><D><V><K><I><S><E><L><T><E><E><Q><I><D><Q><L><R><D><G><V><A><K><Y><T><V><E><G><D><L><R><R><E><V><S><M><N><I><K><R><L><M><D><L><G><C><Y><R><G><L><R><H><R><R><S><L><P><L><R><G><Q><R><T><K><T><N><A><R...
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.<...
Q87SZ2
A0A5Q0QN66
AGR6_AGRAE
Terpene cyclase Agr6
Cyclocybe
<M><P><G><S><A><N><W><T><A><D><R><F><Y><I><P><D><T><L><A><N><W><P><W><P><R><A><I><N><P><A><Y><E><E><C><K><A><A><S><A><A><W><C><E><K><Y><G><A><F><S><A><R><A><Q><K><A><F><N><L><C><D><F><N><L><L><A><S><L><A><Y><A><G><L><P><A><D><V><N><R><V><G><C><D><L><M><N><L><F><F><V><V><D><E><H><T><D><A><M><D><A><R><S><V><Q><D><W><V><D...
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to delta(6)-protoilludene.<BOP>
A0A5Q0QN66
P0C7I1
CM3E_CONPI
Psi-conotoxin pr3e
Phasmoconus
<M><S><K><L><G><V><L><L><T><I><C><L><L><L><F><P><I><T><A><L><P><V><D><G><D><Q><P><A><D><R><P><V><E><R><M><Q><D><N><I><S><S><E><Q><H><P><F><F><E><K><R><A><A><R><C><C><T><Y><H><G><S><C><L><K><E><K><C><R><R><K><Y><C><C><G><R>
Psi-conotoxins act on postsynaptic membranes, and act as non-competitive antagonist of nicotinic acetylcholine receptors (nAChR). Reversibly inhibits both adult- and fetal-types nAChR. The inhibition potency against the adult- (alpha-1/beta-1/epsilon/delta) is higher than against the fetal-type (alpha-1/beta-1/gamma/de...
P0C7I1
C4Z520
FMT_LACE2
Methionyl-tRNA formyltransferase
Lachnospira
<M><R><V><V><F><M><G><T><P><D><F><A><V><G><T><L><K><A><I><I><E><A><G><H><D><V><A><A><V><V><T><Q><P><D><K><P><R><G><R><S><K><S><L><V><F><S><P><V><K><D><E><A><V><A><H><G><I><T><V><L><Q><P><E><R><A><R><D><E><A><F><V><E><E><L><R><T><Y><N><A><D><V><I><V><V><V><A><F><G><Q><L><L><P><A><S><I><I><N><M><P><R><Y><G><C><I><N><V><H...
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.<BOP>
C4Z520
Q9KVE0
MURQ1_VIBCH
N-acetylmuramic acid 6-phosphate lyase 1
Vibrio
<M><K><I><D><L><T><R><L><V><T><E><S><R><N><P><A><S><E><Q><I><D><T><L><P><T><L><D><M><L><K><V><I><N><Q><Q><D><Q><L><V><A><L><A><V><A><Q><T><L><P><Q><V><A><Q><A><V><E><A><I><A><T><A><F><A><Q><G><G><R><L><I><Y><M><G><A><G><T><S><G><R><L><G><I><L><D><A><S><E><C><P><P><T><Y><G><S><Q><P><E><Q><V><I><G><L><I><A><G><G><H><T><A...
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus...
Q9KVE0
B9L9C2
COAD_NAUPA
Pantetheine-phosphate adenylyltransferase
Nautilia
<M><Y><T><K><A><I><Y><P><G><T><F><D><P><V><T><N><G><H><L><D><I><I><K><R><A><C><K><M><F><D><K><I><I><V><A><V><A><D><N><K><D><K><K><T><M><F><S><L><E><K><R><V><E><L><M><K><K><A><T><S><H><L><P><K><I><E><V><E><S><F><N><S><L><L><V><D><F><A><R><E><K><E><C><K><I><I><I><R><G><L><R><A><V><S><D><F><E><Y><E><L><Q><M><G><Y><A><N><K...
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP>
B9L9C2
A0A0B5LB55
MPAH2_PENBR
Mycophenolic acid biosynthesis cluster protein H'
Penicillium
<M><S><T><E><K><F><T><I><T><E><H><L><V><P><G><S><H><I><R><E><Y><P><G><S><T><V><N><Q><E><D><V><L><K><I><H><V><K><Q><Y><T><P><K><R><E><G><P><V><P><D><D><A><I><T><F><I><A><T><H><G><V><G><L><P><K><E><L><Y><E><P><L><W><D><E><L><L><D><Q><A><S><G><F><H><I><R><A><I><W><M><A><D><V><A><S><M><N><Q><S><G><I><H><N><E><D><K><L><S><M...
Type I acyl-CoA thioesterase; part of the gene cluster that mediates the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893 . MpaH' acts as a peroxisomal acyl-CoA hydrolase that converts MPA-CoA into the final...
A0A0B5LB55
A1JKR7
NDK_YERE8
Nucleoside-2-P kinase
Yersinia
<M><A><V><E><R><T><F><S><I><I><K><P><N><A><V><A><K><N><N><I><G><A><I><Y><A><R><F><E><S><A><G><F><K><I><I><A><A><K><M><L><H><L><T><K><E><Q><A><E><G><F><Y><A><E><H><K><G><R><P><F><F><D><G><L><V><E><F><M><T><S><G><P><V><M><I><Q><V><L><E><G><E><N><A><V><Q><R><H><R><D><I><M><G><A><T><N><P><D><N><A><L><A><G><T><L><R><A><D><F...
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.<BOP>
A1JKR7
P20119
PSAF_PEA
PSI-F
Pisum
<A><I><S><G><L><T><P><C><K><E><S><K><Q><F><A><K><R><E><K><Q>
Probably participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria). This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.<BOP>
P20119
Q1DEM0
POMZ_MYXXD
Positioning at midcell of FtsZ
Myxococcus
<M><E><A><P><T><Y><S><S><K><Q><V><A><E><M><L><G><V><S><P><K><Q><I><P><E><E><S><R><K><D><A><Y><T><P><D><D><I><W><E><L><R><T><T><L><D><R><F><P><A><R><L><G><H><R><R><Q><L><F><L><N><F><K><G><G><T><G><K><T><S><L><S><T><S><Y><A><W><R><L><A><E><L><G><Y><A><V><L><L><I><D><L><D><S><Q><G><H><A><T><K><C><L><G><Y><E><G><E><D><F><E...
Spatial regulator of cell division that is involved in identifying the incipient division site, recruiting FtsZ to the division site and stabilizing the Z-ring. Binds ATP and GTP.<BOP>
Q1DEM0
Q48LF6
MNMC_PSE14
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Pseudomonas
<M><T><I><T><R><H><A><R><I><D><W><D><E><Q><G><N><P><R><S><R><D><F><S><D><V><Y><F><S><T><E><S><G><L><D><E><T><R><H><V><F><L><V><Q><N><D><L><R><R><R><F><S><E><L><P><E><D><G><R><L><I><I><G><E><T><G><F><G><T><G><L><N><F><L><C><A><W><Q><L><F><D><E><C><A><P><A><E><A><R><L><Q><F><V><S><V><E><K><Y><P><L><S><R><A><D><L><Q><R><A...
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s...
Q48LF6
Q24UN9
QUEA_DESHY
Queuosine biosynthesis protein QueA
Desulfitobacterium
<M><K><L><E><D><F><D><F><E><L><P><E><D><R><I><A><Q><H><P><V><E><P><R><D><S><S><R><L><M><V><M><N><R><W><T><G><E><I><E><H><R><V><F><R><E><L><P><E><L><L><Q><A><G><D><V><L><V><V><N><N><T><R><V><I><P><A><R><L><I><G><E><K><E><G><T><Q><A><K><I><E><C><L><L><L><T><R><R><D><K><D><V><W><E><T><L><I><K><P><G><K><R><L><K><A><G><Q><T...
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).<BOP>
Q24UN9
P67657
MTNN_MYCBO
S-adenosylhomocysteine nucleosidase
Mycobacterium tuberculosis complex
<M><A><V><T><V><G><V><I><C><A><I><P><Q><E><L><A><Y><L><R><G><V><L><V><D><A><K><R><Q><Q><V><A><Q><I><L><F><D><S><G><Q><L><D><A><H><R><V><V><L><A><A><A><G><M><G><K><V><N><T><G><L><T><A><T><L><L><A><D><R><F><G><C><R><T><I><V><F><T><G><V><A><G><G><L><D><P><E><L><C><I><G><D><I><V><I><A><D><R><V><V><Q><H><D><F><G><L><L><T><D...
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethio...
P67657
A7I1F0
LEPA_CAMHC
Ribosomal back-translocase LepA
Campylobacter
<M><E><N><I><R><N><F><S><I><I><A><H><I><D><H><G><K><S><T><L><A><D><R><L><I><S><E><C><N><A><V><E><D><R><Q><M><S><S><Q><V><M><D><T><M><D><I><E><R><E><R><G><I><T><I><K><A><Q><S><V><R><L><E><Y><K><M><N><D><K><K><Y><I><L><N><L><I><D><T><P><G><H><V><D><F><S><Y><E><V><S><R><S><L><A><S><C><E><G><A><I><L><V><V><D><A><S><Q><G><V...
Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-t...
A7I1F0
A9IR81
DAPE_BORPD
N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase
Bordetella
<M><T><A><D><S><A><V><L><A><L><V><R><E><L><I><A><R><P><S><V><T><P><D><D><V><D><C><Q><L><L><L><A><Q><R><L><E><H><A><G><F><R><C><E><T><I><A><R><G><D><V><T><N><L><W><A><R><R><G><N><A><G><P><L><V><V><F><A><G><H><T><D><V><V><P><P><G><P><R><D><K><W><D><S><D><P><F><V><P><T><E><R><D><G><Y><L><Y><G><R><G><A><A><D><M><K><S><S><I...
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.<BOP>
A9IR81
Q2MFP3
DOIAD_STREY
2-deoxy-scyllo-inosamine dehydrogenase
Streptomyces
<M><K><A><L><M><F><K><A><P><L><Q><A><V><L><T><E><R><D><V><P><E><P><A><P><G><E><A><L><V><K><L><A><Y><N><S><I><C><G><S><D><L><S><F><Y><K><G><V><W><H><G><F><T><Y><P><V><V><P><G><H><E><W><S><G><T><V><V><E><A><G><G><G><A><A><D><L><V><G><Q><N><V><V><G><D><L><T><V><A><C><G><S><C><R><H><C><T><V><G><K><P><T><L><C><A><D><L><Q><E...
Catalyzes the oxidation of 2-deoxy-scyllo-inosamine (DOIA) with NAD(+) or NADP(+), forming 3-amino-2,3-dideoxy-scyllo-inosose (amino-DOI).<BOP>
Q2MFP3
A1ALV7
RL18_PELPD
50S ribosomal protein L18
Pelobacter
<M><A><R><T><A><Q><K><L><I><T><R><I><K><R><K><V><R><V><R><K><K><I><V><G><T><A><Q><R><P><R><L><N><V><F><K><S><A><R><H><I><Y><A><Q><L><I><D><D><T><A><G><I><T><L><A><S><C><S><T><L><S><T><S><A><E><S><L><S><Y><T><G><N><I><A><A><A><V><H><V><G><K><E><I><A><G><L><A><K><E><K><N><I><T><A><V><V><F><D><R><N><G><F><L><Y><H><G><R><I...
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP>
A1ALV7
A1KB15
RL5_AZOSB
50S ribosomal protein L5
Azoarcus
<M><A><R><L><Q><Q><F><Y><K><D><E><V><V><P><Q><L><L><K><Q><F><G><Y><K><S><V><M><E><V><P><R><I><T><K><I><T><L><N><M><G><V><G><E><A><V><G><D><K><K><V><L><E><N><A><I><G><D><M><T><K><I><A><G><Q><K><P><V><A><T><K><A><R><K><S><I><A><G><F><K><I><R><E><G><Y><P><I><G><C><M><V><T><L><R><G><P><R><M><F><E><F><F><D><R><L><V><T><V><A...
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement...
A1KB15
C0Z887
UNG_BREBN
Uracil-DNA glycosylase
Brevibacillus
<M><T><T><I><L><Q><N><D><W><A><P><V><L><A><D><E><F><E><K><P><Y><Y><V><K><L><R><Q><T><L><K><E><E><Y><Q><T><Q><T><I><Y><P><D><M><F><H><I><F><T><A><L><H><L><T><E><Y><Q><N><A><K><V><V><I><L><G><Q><D><P><Y><H><G><P><G><Q><A><H><G><L><S><F><S><V><K><P><G><I><K><P><P><P><S><L><V><N><I><Y><K><E><L><K><S><D><V><G><F><E><I><P><Q...
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.<BOP>
C0Z887
O81185
CAMT1_EUCGL
Trans-caffeoyl-CoA 3-O-methyltransferase 1
Eucalyptus
<M><A><T><A><G><E><E><S><Q><T><Q><A><G><R><H><Q><E><V><G><H><K><S><L><L><Q><S><D><A><L><Y><Q><H><I><L><E><T><S><V><Y><P><R><E><P><E><P><M><K><E><L><R><E><I><T><A><K><H><P><W><N><I><M><T><T><S><A><D><E><G><Q><F><L><N><M><L><L><K><L><I><N><A><K><N><T><M><E><I><G><V><F><T><G><Y><S><L><L><A><T><A><L><A><L><P><D><D><G><K><I...
Methylates caffeoyl-CoA to feruloyl-CoA and 5-hydroxyferuloyl-CoA to sinapoyl-CoA. Plays a role in the synthesis of feruloylated polysaccharides. Involved in the reinforcement of the plant cell wall. Also involved in the responding to wounding or pathogen challenge by the increased formation of cell wall-bound ferulic ...
O81185
P0C252
I2BA_CONEM
Kappa-conotoxin-like Em11.10
Virgiconus
<C><F><P><P><G><I><Y><C><T><P><Y><L><P><C><C><W><G><I><C><C><G><T><C><R><N><V><C><H><L><R><I><G><K><R><A><T><F><Q><E>
Inhibits the vertebrate voltage-gated potassium channels Kv1.1/KCNA1 and Kv1.3/KCNA3.<BOP>
P0C252
O30444
PXPA_BORPE
5-oxoprolinase (ATP-hydrolyzing) subunit A
Bordetella
<M><N><P><A><I><D><L><N><C><D><M><G><E><S><Y><G><A><W><R><M><G><N><D><E><A><V><L><Q><F><V><T><S><A><N><I><A><C><G><F><H><G><G><D><P><S><T><M><R><Q><T><V><A><A><A><L><A><H><G><V><A><L><G><A><H><P><S><L><P><D><L><A><G><F><G><R><R><A><M><Q><I><T><P><Q><E><A><Y><D><L><V><V><Y><Q><V><G><A><L><A><G><V><A><A><S><Q><G><A><R><L...
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.<BOP>
O30444
B1KKX6
MURC_SHEWM
UDP-N-acetylmuramoyl-L-alanine synthetase
Shewanella
<M><G><N><D><K><E><K><Y><S><K><L><R><N><I><I><P><E><M><R><R><V><K><H><I><Y><F><V><G><I><G><G><A><G><M><G><G><I><A><E><V><L><V><N><E><G><Y><R><L><S><G><S><D><I><A><E><N><A><V><T><Q><R><L><A><S><L><G><A><K><I><H><L><G><H><K><E><E><Q><V><H><G><A><D><V><V><V><V><S><T><A><I><H><A><D><N><P><E><L><L><E><A><Q><A><L><R><I><P><V...
Cell wall formation.<BOP>
B1KKX6
A9MFB6
BTUC_SALAR
Vitamin B12 import system permease protein BtuC
Salmonella
<M><D><N><M><L><T><F><A><R><Q><Q><Q><R><R><N><V><R><W><L><L><S><L><S><L><L><V><L><L><A><T><L><L><S><L><C><A><G><E><Q><W><I><A><P><G><D><W><L><S><S><R><G><E><L><F><V><W><Q><I><R><L><P><R><T><L><A><V><L><L><V><G><A><S><L><A><L><S><G><A><V><M><Q><A><L><F><E><N><P><L><A><E><P><G><L><L><G><V><S><N><G><A><G><V><G><L><I><A><A...
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane.<BOP>
A9MFB6
Q9FUR2
IP5P2_ARATH
Type I inositol polyphosphate 5-phosphatase 2
Arabidopsis
<M><K><T><R><R><G><K><R><P><E><R><F><W><P><S><I><V><M><N><K><W><L><N><R><K><P><K><V><Y><D><F><S><E><D><E><I><D><T><E><P><E><S><E><D><D><V><C><S><V><K><D><V><P><N><V><H><C><V><T><D><E><D><S><H><N><G><R><R><G><S><E><A><D><H><G><N><N><I><S><D><G><G><V><S><V><R><G><G><Y><Q><R><K><H><R><R><G><K><S><E><T><L><R><A><Q><Y><I><N...
Has phosphatase activity toward Ins(1,4,5)P3 and Ins(1,3,4,5)P4. Seems to be involved in the abscisic acid (ABA) signaling pathway . Could also be able to hydrolyze PtdIns(4,5)P2 and PtdIns(3,4,5)P3 .<BOP>
Q9FUR2
Q8KA19
RNFD_BUCAP
Rnf electron transport complex subunit D
Buchnera
<M><K><L><K><K><M><N><L><P><Y><I><S><N><T><Y><D><V><R><K><I><M><F><L><V><V><L><S><C><I><P><G><L><C><T><E><I><Y><F><F><G><C><G><V><L><I><Q><T><L><L><F><V><I><I><S><L><L><F><E><I><I><I><L><K><M><R><R><K><N><I><K><N><S><L><F><D><Y><S><S><F><L><T><A><V><L><L><G><L><S><T><P><C><A><L><P><W><W><M><I><I><F><S><C><F><F><A><I><V...
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.<BOP>
Q8KA19
Q835U7
RBFA_ENTFA
Ribosome-binding factor A
Enterococcus
<M><A><N><Y><R><D><R><R><V><G><Q><E><I><M><R><E><V><N><D><I><L><N><K><R><I><R><D><P><R><V><Q><G><I><T><I><T><D><V><R><V><T><G><D><L><Q><Q><A><T><I><Y><Y><S><L><L><S><D><L><A><S><E><Q><Q><K><A><Q><Q><G><L><D><K><A><K><G><L><I><R><K><E><L><G><Q><R><L><T><L><Y><K><T><P><E><L><I><F><E><R><D><E><S><V><Q><Y><G><N><H><I><D><E...
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli...
Q835U7
Q5L8A5
RS12_BACFN
30S ribosomal protein S12
Bacteroides
<M><P><T><I><Q><Q><L><V><R><K><G><R><E><V><L><V><E><K><S><K><S><P><A><L><D><S><C><P><Q><R><R><G><V><C><V><R><V><Y><T><T><T><P><K><K><P><N><S><A><M><R><K><V><A><R><V><R><L><T><N><Q><K><E><V><N><S><Y><I><P><G><E><G><H><N><L><Q><E><H><S><I><V><L><V><R><G><G><R><V><K><D><L><P><G><V><R><Y><H><I><V><R><G><T><L><D><T><A><G><V...
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com...
Q5L8A5
B4FHY0
FEN1_MAIZE
Flap structure-specific endonuclease 1
Zea
<M><G><I><K><G><L><T><K><L><L><A><D><N><A><P><K><A><M><K><E><Q><K><F><E><S><Y><F><G><R><K><I><A><V><D><A><S><M><S><I><Y><Q><F><L><I><V><V><G><R><T><G><M><E><T><L><T><N><E><A><G><E><V><T><S><H><L><Q><G><M><F><N><R><T><I><R><L><L><E><A><G><I><K><P><V><Y><V><F><D><G><K><P><P><D><M><K><K><Q><E><L><A><K><R><Y><S><K><R><D><D...
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It ente...
B4FHY0
Q3T9M1
MFS2B_MOUSE
Major facilitator superfamily domain-containing protein 2B
Mus
<M><S><V><P><H><G><P><T><P><A><P><V><A><E><P><H><T><Q><E><P><G><S><D><K><R><D><G><R><L><S><V><C><T><K><V><C><Y><G><I><G><G><V><P><N><Q><V><A><S><S><A><S><A><F><Y><L><Q><L><F><L><L><D><V><A><Q><I><P><A><A><Q><V><S><L><A><L><F><G><G><K><V><S><G><A><V><A><D><P><V><A><G><F><F><I><N><K><S><R><R><T><G><S><G><R><L><M><P><W><A...
Lipid transporter that specifically mediates export of sphingosine-1-phosphate in red blood cells and platelets . Sphingosine-1-phosphate is a signaling sphingolipid and its export from red blood cells into in the plasma is required for red blood cell morphology . Sphingosine-1-phosphate export from platelets is requir...
Q3T9M1
Q8EPJ4
MURI_OCEIH
Glutamate racemase
Oceanobacillus
<M><D><K><S><I><G><V><I><D><S><G><V><G><G><L><T><V><V><H><E><L><M><R><Q><L><P><K><E><Q><L><I><Y><L><G><D><T><A><R><C><P><Y><G><P><R><S><K><E><E><V><R><Q><F><T><W><E><M><V><D><F><L><L><T><K><N><I><K><M><L><V><V><A><C><N><T><A><T><A><F><T><L><K><D><L><K><E><Q><L><D><I><P><V><I><G><V><I><Q><P><G><A><R><A><A><I><K><S><T><T...
Provides the (R)-glutamate required for cell wall biosynthesis.<BOP>
Q8EPJ4
B0BPT5
GAL1_ACTPJ
Galactose kinase
Actinobacillus
<M><K><P><Q><Q><L><A><T><Q><K><F><S><E><H><Y><G><Y><S><A><A><Q><T><V><F><A><P><G><R><V><N><I><I><G><E><H><T><D><Y><N><D><G><F><V><M><P><C><A><I><N><Y><G><M><A><V><S><F><S><K><R><D><D><S><V><W><R><V><Y><A><I><D><I><D><E><Q><D><E><F><D><L><S><R><P><I><E><P><S><E><H><K><W><A><N><Y><V><R><G><V><V><K><Y><I><Q><E><K><C><P><E...
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).<BOP>
B0BPT5
Q5HAK8
FOLD_EHRRW
Methenyltetrahydrofolate cyclohydrolase
Ehrlichia
<M><E><G><N><I><V><S><G><K><A><V><A><D><N><I><T><N><I><L><A><T><C><I><S><D><L><K><A><Q><H><N><L><T><P><C><L><I><V><V><L><V><G><D><D><P><A><S><Q><L><Y><V><R><N><K><Q><R><K><A><E><M><L><G><L><R><S><E><T><M><L><L><P><S><T><I><S><E><S><S><L><I><E><K><I><H><Q><L><N><N><D><D><S><V><H><G><I><L><V><Q><L><P><V><P><R><H><I><D><K...
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP>
Q5HAK8
F4IS56
ILK1_ARATH
Ankyrin protein kinase 1
Arabidopsis
<M><E><N><I><T><A><Q><L><K><R><G><I><S><R><Q><F><S><T><G><S><I><R><R><T><L><S><R><Q><F><T><R><Q><S><S><L><D><P><R><R><T><N><M><R><F><S><F><G><R><Q><S><S><L><D><P><I><R><R><S><P><D><S><S><K><S><D><D><E><P><H><M><S><V><P><E><N><L><D><S><T><M><Q><L><L><F><M><A><S><K><G><D><V><R><G><I><E><E><L><L><D><E><G><I><D><V><N><S><I...
Functions as a link between plant defense pathways, stress responses and potassium homeostasis. Promotes osmotic stress sensitivity, responses to the bacterial-derived pathogen-associated molecular pattern (PAMP) flg22, and resistance to bacterial pathogens. Promotes the accumulation of POT5/HAK5, a potassium transport...
F4IS56
A9MJ57
TRUA_SALAR
tRNA-uridine isomerase I
Salmonella
<M><S><G><Q><Q><S><S><P><V><Y><K><I><A><L><G><I><E><Y><D><G><S><K><Y><Y><G><W><Q><R><Q><N><E><V><R><S><V><Q><E><K><L><E><K><A><L><S><Q><V><A><N><E><P><I><N><V><F><C><A><G><R><T><D><A><G><V><H><G><T><G><Q><V><V><H><F><E><T><T><A><L><R><K><D><V><A><W><T><L><G><V><N><A><N><L><P><G><D><I><A><V><R><W><V><K><A><V><A><D><D><F...
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP>
A9MJ57
Q4ZP20
CH60_PSEU2
Chaperonin-60
Pseudomonas syringae
<M><A><A><K><E><V><K><F><G><D><S><G><R><K><K><M><L><A><G><V><N><V><L><A><D><A><V><K><A><T><L><G><P><K><G><R><N><V><I><I><E><K><S><F><G><A><P><L><I><T><K><D><G><V><S><V><A><K><E><I><E><L><K><D><R><F><E><N><M><G><A><Q><L><V><K><D><V><A><S><R><A><N><D><D><A><G><D><G><T><T><T><A><T><V><L><A><Q><A><I><V><N><E><G><L><K><A><V...
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP>
Q4ZP20
Q8S2G5
GPDH2_ORYSJ
Probable glycerol-3-phosphate dehydrogenase [NAD(+)] 2, cytosolic
Oryza sativa
<M><G><G><A><E><D><A><P><R><A><A><A><A><N><G><H><G><N><G><A><T><V><E><E><K><L><D><E><L><R><R><L><L><G><K><A><D><G><D><P><L><R><I><V><G><V><G><A><G><A><W><G><S><V><F><C><A><L><M><Q><D><A><Y><G><H><L><R><D><K><V><Q><V><R><I><W><R><R><P><G><R><A><V><D><R><A><T><A><E><H><L><F><E><V><I><N><A><R><E><D><V><L><R><R><L><I><R><R...
May be involved in cell redox homeostasis.<BOP>
Q8S2G5
P22663
VATB_METBA
V-ATPase subunit B
Methanosarcina
<M><V><K><E><Y><K><T><I><T><Q><I><A><G><P><L><V><F><V><E><K><T><E><P><V><G><Y><K><E><I><V><T><I><N><L><P><D><G><T><T><R><R><G><E><V><L><D><S><S><S><D><I><V><V><I><Q><I><F><E><G><T><T><G><L><D><K><E><C><G><V><V><F><T><G><E><T><L><K><L><P><A><S><I><D><L><L><G><R><I><L><S><G><S><G><E><P><L><D><G><G><P><R><I><V><P><D><Q><L...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.<BOP>
P22663
Q6LT88
MINE_PHOPR
Cell division topological specificity factor
Photobacterium
<M><A><L><L><E><F><F><R><P><K><K><T><T><T><A><S><V><A><K><E><R><L><Q><I><I><V><A><E><R><R><S><A><G><Q><S><T><P><S><Y><L><P><Q><L><K><L><D><L><L><E><V><I><R><K><Y><V><N><I><N><P><D><Q><V><S><V><N><L><D><Q><K><D><E><D><L><S><V><L><E><L><N><V><T><L><P><E><D><K>
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.<BOP>
Q6LT88
Q7VXD7
RIMM_BORPE
Ribosome maturation factor RimM
Bordetella
<M><S><E><A><A><H><S><G><A><A><P><A><D><L><V><E><L><G><R><I><A><S><A><Y><G><V><K><G><W><V><K><V><Q><P><H><S><A><Q><A><E><V><L><R><T><V><S><H><W><W><L><T><R><P><A><P><Q><A><A><R><D><V><V><A><S><V><P><R><A><Y><Q><V><L><Q><A><R><V><H><G><G><A><V><V><A><Q><L><A><G><I><D><D><R><D><Q><A><E><A><L><R><G><C><F><V><Q><A><A><R><S...
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma...
Q7VXD7
O75586
MED6_HUMAN
Renal carcinoma antigen NY-REN-28
Homo
<M><A><A><V><D><I><R><D><N><L><L><G><I><S><W><V><D><S><S><W><I><P><I><L><N><S><G><S><V><L><D><Y><F><S><E><R><S><N><P><F><Y><D><R><T><C><N><N><E><V><V><K><M><Q><R><L><T><L><E><H><L><N><Q><M><V><G><I><E><Y><I><L><L><H><A><Q><E><P><I><L><F><I><I><R><K><Q><Q><R><Q><S><P><A><Q><V><I><P><L><A><D><Y><Y><I><I><A><G><V><I><Y><Q...
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters...
O75586
Q9ZKZ0
HLDE_HELPJ
D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase
Helicobacter
<M><K><K><I><L><V><I><G><D><L><I><A><D><Y><Y><L><W><G><K><S><E><R><L><S><P><E><A><P><V><P><V><L><E><V><K><K><E><S><K><N><L><G><G><A><A><N><V><A><N><N><L><T><S><L><K><A><K><V><F><L><C><G><V><V><G><D><D><L><E><G><K><H><F><I><S><T><L><K><T><R><G><I><D><T><S><G><V><L><I><D><K><T><R><C><T><T><L><K><T><R><I><I><A><Q><N><Q><Q...
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.<BOP>
Q9ZKZ0
A7ZG10
RL23_CAMC1
50S ribosomal protein L23
Campylobacter
<M><A><D><I><T><D><I><K><T><I><I><Y><T><E><K><T><L><G><L><Q><E><Q><G><V><V><V><I><Q><T><S><P><R><V><T><K><N><S><L><K><A><V><L><Q><E><Y><F><G><V><T><P><V><R><V><N><S><L><R><I><S><G><K><V><K><R><F><R><G><R><A><G><Q><R><D><E><I><K><K><F><Y><V><K><L><P><E><G><V><S><L><E><N><T><E><A>
One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.<BOP>
A7ZG10
Q9Y7U9
CCA2_SCHPO
tRNA adenylyltransferase cca2
Schizosaccharomyces
<M><Y><S><R><I><V><L><N><D><V><E><K><K><V><V><N><L><L><K><K><T><A><D><F><I><E><S><K><S><S><S><S><S><S><L><E><V><R><L><A><G><G><W><V><R><D><K><L><L><G><L><S><S><D><D><L><D><V><T><L><N><K><V><T><G><V><D><F><A><N><S><I><F><E><Y><V><H><S><L><D><S><D><S><V><I><P><Y><K><D><A><L><G><K><L><T><V><N><P><D><Q><S><K><H><L><E><T><A...
tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. In contrast to what is usually observed in eukaryotes for which one enzyme synthesizes the whole tRNA CCA terminus, in S.pombe, cca1 specifically adds two cytidine residues to a tRNA substrate lacking this sequence while cca2 specifically a...
Q9Y7U9
Q1HPS4
EIF3K_BOMMO
eIF-3 p25
Bombyx
<M><T><D><T><M><A><E><T><M><K><Q><T><V><A><S><I><L><K><S><I><E><R><Y><N><P><A><N><L><E><I><L><E><R><Y><V><E><M><Q><S><R><E><N><T><Y><D><W><G><A><N><L><A><V><L><K><L><Y><Q><F><N><P><E><K><F><N><A><D><I><T><C><Q><I><L><L><K><A><L><T><N><F><P><H><T><D><F><T><L><C><K><C><L><L><L><E><S><V><V><E><N><E><T><I><S><Q><I><K><Y><L...
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates t...
Q1HPS4
Q9L0Q8
ISPD_STRCO
MEP cytidylyltransferase
Streptomyces albidoflavus group
<M><S><D><E><S><R><P><S><P><A><E><T><P><A><T><T><F><A><E><T><S><A><E><T><S><A><A><G><R><S><P><A><R><T><A><A><V><I><P><A><A><G><R><G><V><R><L><G><P><G><A><P><K><A><L><R><A><L><G><G><T><P><M><L><I><H><A><V><R><A><M><A><A><S><R><A><V><S><L><V><V><V><V><A><P><P><D><G><A><G><E><V><K><S><L><L><D><A><H><A><L><P><E><R><T><D><F...
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
Q9L0Q8
P14490
REPM_STAAU
Replication initiation protein
Staphylococcus
<M><S><K><N><N><Y><T><N><H><S><N><H><L><E><N><H><D><S><D><N><F><S><K><T><G><Y><S><N><S><R><L><D><A><H><F><V><C><T><S><N><P><K><L><S><F><D><A><M><T><I><V><G><N><L><N><K><N><S><A><K><K><L><S><D><F><M><S><L><D><P><Q><I><R><L><W><D><I><L><Q><T><K><F><K><A><K><A><L><Q><E><K><V><Y><I><E><Y><D><K><V><K><A><D><T><W><D><R><R><N...
This protein is probably a specific topoisomerase involved in initiating replication. This protein is specifically required and may be rate-limiting for replication of the plasmid in vivo.<BOP>
P14490
Q8XIT6
PRMA_CLOPE
Ribosomal protein L11 methyltransferase
Clostridium
<M><E><G><T><W><I><E><V><R><V><I><T><K><S><E><A><L><E><P><I><S><G><I><F><Y><G><L><D><C><K><G><V><A><I><E><D><P><N><D><I><L><G><R><E><Q><G><P><L><T><W><D><F><A><D><I><N><I><L><E><H><K><G><K><V><A><V><V><K><G><Y><F><S><E><E><D><N><I><D><D><V><I><A><Y><V><K><E><R><V><E><E><L><K><E><S><G><L><D><V><G><E><G><T><V><E><A><E><K...
Methylates ribosomal protein L11.<BOP>
Q8XIT6
Q9Y3E1
HDGR3_HUMAN
Hepatoma-derived growth factor 2
Homo
<M><A><R><P><R><P><R><E><Y><K><A><G><D><L><V><F><A><K><M><K><G><Y><P><H><W><P><A><R><I><D><E><L><P><E><G><A><V><K><P><P><A><N><K><Y><P><I><F><F><F><G><T><H><E><T><A><F><L><G><P><K><D><L><F><P><Y><K><E><Y><K><D><K><F><G><K><S><N><K><R><K><G><F><N><E><G><L><W><E><I><E><N><N><P><G><V><K><F><T><G><Y><Q><A><I><Q><Q><Q><S><S...
Enhances DNA synthesis and may play a role in cell proliferation.<BOP>
Q9Y3E1
Q28MN0
GLGA_JANSC
Starch [bacterial glycogen] synthase
unclassified Jannaschia
<M><T><R><V><L><S><V><A><S><E><C><A><P><L><V><K><T><G><G><L><A><D><V><V><G><A><L><P><G><A><M><A><A><L><G><D><E><L><R><T><L><V><P><G><Y><A><T><M><P><V><V><G><G><A><V><V><A><A><F><D><D><L><F><G><G><P><A><T><V><D><A><L><T><H><E><G><L><D><L><L><I><L><R><A><P><H><L><F><D><R><P><G><G><L><Y><I><D><A><F><G><A><D><W><P><D><N><A...
Synthesizes alpha-1,4-glucan chains using ADP-glucose.<BOP>
Q28MN0
Q0VN37
LIPB_ALCBS
Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase
Alcanivorax
<M><H><S><W><P><Y><T><S><P><M><D><A><L><I><R><Y><F><P><Q><V><D><Y><S><S><C><W><H><A><M><R><D><L><T><D><H><R><D><A><Q><Q><S><D><E><F><W><V><L><E><H><P><P><I><F><T><L><G><Q><A><G><K><P><E><H><V><L><N><A><G><E><I><P><V><V><N><S><D><R><G><G><Q><V><T><Y><H><G><P><G><Q><T><V><V><Y><L><M><L><D><I><K><R><L><G><L><G><S><R><G><L...
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.<BOP>
Q0VN37
Q72I19
RL6_THET2
50S ribosomal protein L6
Thermus
<M><S><R><I><G><R><L><P><I><P><V><P><K><G><V><S><V><E><V><A><P><G><R><V><K><V><K><G><P><K><G><E><L><E><V><P><V><S><P><E><M><R><V><V><V><E><E><G><V><V><R><V><E><R><P><S><D><E><R><R><H><K><S><L><H><G><L><T><R><T><L><I><A><N><A><V><K><G><V><S><E><G><Y><S><K><E><L><L><I><K><G><I><G><Y><R><A><R><L><V><G><R><A><L><E><L><T><V...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
Q72I19
Q9HAI6
TASL_HUMAN
TLR adapter interacting with SLC15A4 on the lysosome
Homo
<M><L><S><E><G><Y><L><S><G><L><E><Y><W><N><D><I><H><W><S><C><A><S><Y><N><E><Q><V><A><G><E><K><E><E><E><T><N><S><V><A><T><L><S><Y><S><S><V><D><E><T><Q><V><R><S><L><Y><V><S><C><K><S><S><G><K><F><I><S><S><V><H><S><R><E><S><Q><H><S><R><S><Q><R><V><T><V><L><Q><T><N><P><N><P><V><F><E><S><P><N><L><A><A><V><E><I><C><R><D><A><S...
Innate immune adapter that mediates the recruitment and activation of IRF5 downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9 . Following recruitment to endolysosome by SLC15A4 downstream of TLR7, TLR8 and TLR9, specifically recruits IRF5 transcription factor via its pLxIS motif, leading to IRF5 activa...
Q9HAI6
Q1GF45
COBQ_RUEST
Cobyric acid synthase
unclassified Ruegeria
<M><I><Q><G><T><G><S><N><V><G><K><S><M><L><V><A><G><L><A><R><A><L><R><K><R><G><L><S><V><A><P><F><K><P><Q><N><M><S><N><N><A><A><V><T><S><D><G><G><E><I><G><R><A><Q><A><L><Q><A><R><A><A><G><L><A><P><H><T><D><M><N><P><V><L><L><K><P><E><T><D><T><G><A><Q><V><I><V><Q><G><K><R><R><G><T><R><A><A><G><S><F><M><R><D><K><A><G><L><L...
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.<BOP>
Q1GF45
A5D7U4
SCNNB_BOVIN
SCNEB
Bos
<M><H><V><K><K><Y><L><L><K><G><L><H><R><L><Q><K><G><P><G><Y><T><Y><K><E><L><L><V><W><Y><C><D><N><T><N><T><H><G><P><K><R><I><I><C><E><G><P><K><K><K><A><M><W><F><V><L><T><L><L><F><T><S><L><V><C><W><Q><W><G><L><F><I><K><T><Y><L><N><W><E><V><S><V><S><L><S><I><G><F><K><T><M><D><F><P><A><V><T><I><C><N><A><S><P><F><Q><Y><S><K...
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway su...
A5D7U4
Q2SU28
RL4_BURTA
50S ribosomal protein L4
pseudomallei group
<M><E><L><K><L><L><N><S><N><G><Q><E><G><A><V><V><N><A><S><D><V><V><F><G><R><D><Y><N><E><A><L><I><H><Q><V><V><V><A><Y><Q><A><N><A><R><Q><G><N><R><A><Q><K><D><R><E><Q><V><K><H><T><T><K><K><P><W><R><Q><K><G><T><G><R><A><R><A><G><M><S><S><S><P><L><W><R><G><G><G><R><I><F><P><N><S><P><D><E><N><F><S><H><K><V><N><K><K><M><H><R...
Forms part of the polypeptide exit tunnel.<BOP>
Q2SU28
Q6KZP8
RS13_PICTO
30S ribosomal protein S13
Picrophilus
<M><A><E><E><N><K><N><N><E><N><F><Q><Y><I><V><R><I><A><N><K><D><L><N><G><E><R><P><L><K><L><A><L><A><D><L><K><G><I><G><L><R><L><S><E><T><I><A><K><K><L><D><L><D><P><D><Q><R><I><G><E><L><G><E><D><K><I><E><E><L><R><K><Y><I><E><G><K><V><Y><D><G><I><P><Y><W><M><Y><N><H><R><R><D><I><T><T><G><K><D><F><N><L><V><S><N><D><L><D><L...
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.<BOP>
Q6KZP8
Q13Z72
SURE_PARXL
Nucleoside 5'-monophosphate phosphohydrolase
Paraburkholderia
<M><R><I><L><L><S><N><D><D><G><Y><L><A><P><G><L><A><A><L><Y><E><A><L><K><P><I><A><D><V><T><V><M><A><P><E><Q><N><C><S><G><A><S><N><S><L><T><L><S><R><P><L><S><V><L><R><S><A><N><G><F><Y><Y><V><N><G><T><P><T><D><S><V><H><I><A><L><T><G><M><L><D><H><R><P><D><L><V><V><S><G><I><N><N><G><Q><N><M><G><E><D><T><L><Y><S><G><T><V><A...
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.<BOP>
Q13Z72
A2S5J7
DAPB_BURM9
4-hydroxy-tetrahydrodipicolinate reductase
pseudomallei group
<M><S><S><M><K><I><A><I><A><G><A><S><G><R><M><G><R><M><L><I><E><A><V><L><A><A><P><D><A><T><L><A><G><A><L><D><R><T><G><S><S><Q><L><G><Q><D><A><G><A><F><L><G><K><Q><T><G><V><A><L><T><D><D><I><E><R><V><C><A><E><A><D><Y><L><I><D><F><T><R><P><E><G><T><L><A><H><L><D><A><A><L><R><H><D><V><K><L><V><I><G><T><T><G><F><S><E><P><Q...
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.<BOP>
A2S5J7
A2BK98
NDK_HYPBU
Nucleoside-2-P kinase
Hyperthermus
<M><P><V><E><R><T><F><V><M><I><K><P><D><G><V><K><R><G><L><V><G><E><I><I><A><R><F><E><R><K><G><L><K><I><K><A><L><K><M><K><W><L><T><R><E><E><A><E><K><L><Y><E><V><H><R><G><K><P><F><F><E><D><L><V><N><F><V><T><S><G><P><V><V><A><M><I><L><E><G><D><S><A><I><E><V><V><R><L><M><I><G><P><T><D><G><R><K><A><P><P><G><T><I><R><G><D><Y...
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.<BOP>
A2BK98
Q3B0J2
SSRP_SYNS9
Small protein B
unclassified Synechococcus
<M><A><K><G><G><V><K><K><A><A><A><A><A><A><R><A><A><A><N><R><L><M><A><D><N><R><Q><A><R><H><Q><Y><E><I><L><E><T><L><E><T><G><I><E><L><V><G><T><E><V><K><S><I><R><N><G><K><A><N><L><R><D><G><F><C><L><I><R><N><G><E><L><Q><L><H><N><V><H><I><S><P><H><S><H><A><S><A><Y><F><N><H><D><P><L><R><T><R><K><L><L><A><H><R><R><E><I><D><K...
Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb...
Q3B0J2
A3QEN9
RNFE_SHELP
Rnf electron transport complex subunit E
Shewanella
<M><S><N><Y><R><D><I><A><W><Q><G><L><W><K><N><N><P><G><L><V><Q><L><L><G><L><C><P><L><L><A><V><T><A><T><L><T><N><A><I><G><L><G><L><A><T><L><V><V><L><V><G><S><N><V><L><V><S><L><V><R><E><F><V><P><K><E><I><R><I><P><V><F><V><M><I><I><A><A><L><V><T><C><V><Q><L><L><I><N><A><Y><A><Y><G><L><Y><L><S><L><G><I><F><L><P><L><I><V><T...
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.<BOP>
A3QEN9
P08253
MMP2_HUMAN
PEX
Homo
<M><E><A><L><M><A><R><G><A><L><T><G><P><L><R><A><L><C><L><L><G><C><L><L><S><H><A><A><A><A><P><S><P><I><I><K><F><P><G><D><V><A><P><K><T><D><K><E><L><A><V><Q><Y><L><N><T><F><Y><G><C><P><K><E><S><C><N><L><F><V><L><K><D><T><L><K><K><M><Q><K><F><F><G><L><P><Q><T><G><D><L><D><Q><N><T><I><E><T><M><R><K><P><R><C><G><N><P><D><V...
Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.<BOP>
P08253
A8AC29
VATA_IGNH4
V-ATPase subunit A
Ignicoccus
<M><A><V><K><G><K><V><L><R><V><R><G><P><V><V><I><A><E><D><M><Q><G><V><Q><M><Y><E><V><V><E><V><G><K><D><G><L><V><G><E><V><T><R><I><T><G><D><K><A><V><I><Q><V><Y><E><D><T><T><G><I><T><P><G><E><P><V><V><G><T><G><S><P><F><S><V><E><L><G><P><G><L><L><S><H><I><F><D><G><I><L><R><P><L><E><S><I><H><E><V><A><K><S><P><F><I><K><R><G...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.<BOP>
A8AC29
A5D4K5
THIC_PELTS
Thiamine biosynthesis protein ThiC
Pelotomaculum
<M><N><Y><A><T><Q><M><E><A><A><R><K><G><I><I><T><R><E><M><E><T><V><A><R><K><E><M><V><D><P><A><K><L><R><E><L><I><A><E><G><R><V><V><I><P><A><N><K><N><H><A><S><L><D><P><C><G><I><G><Q><G><L><R><T><K><I><N><V><N><L><G><V><S><R><D><C><C><N><I><G><M><E><L><E><K><A><R><L><A><I><E><L><K><A><D><A><I><M><D><L><S><C><Y><G><R><T><E...
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP>
A5D4K5
Q7NMC7
HEMH_GLOVI
Protoheme ferro-lyase
Gloeobacter
<M><A><E><V><G><V><L><L><L><N><L><G><G><P><D><K><Q><E><D><V><R><P><F><L><Y><N><L><F><A><D><P><E><I><I><R><I><P><V><P><P><L><Q><K><P><L><A><W><L><I><S><T><L><R><A><P><K><S><R><K><N><Y><Q><A><I><G><G><G><S><P><L><R><A><I><T><N><Q><Q><G><R><V><L><K><K><A><L><A><A><R><G><L><D><I><E><V><Y><V><G><M><R><Y><W><H><P><F><T><E><E...
Catalyzes the ferrous insertion into protoporphyrin IX.<BOP>
Q7NMC7
A7ZQD8
NORR_ECO24
Anaerobic nitric oxide reductase transcription regulator NorR
Escherichia
<M><S><F><S><V><D><V><L><A><N><I><A><I><E><L><Q><R><G><I><G><H><Q><D><R><F><Q><R><L><I><T><T><L><R><Q><V><L><E><C><D><A><S><A><L><L><R><Y><D><S><R><Q><F><I><P><L><A><I><D><G><L><A><K><D><V><L><G><R><R><F><A><L><E><G><H><P><R><L><E><A><I><A><R><A><G><D><V><V><R><F><P><A><D><S><E><L><P><D><P><Y><D><G><L><I><P><G><Q><E><S...
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54.<BOP>
A7ZQD8
B2SQB3
ATPD_XANOP
F-type ATPase subunit delta
Xanthomonas
<M><S><Q><A><L><T><L><A><R><P><Y><G><R><A><A><F><A><I><A><R><E><G><G><T><F><A><P><W><S><D><A><L><A><F><S><A><Q><V><A><G><D><P><R><V><A><A><L><L><L><N><P><A><L><G><Q><E><Q><A><V><T><L><L><A><P><P><Q><A><G><E><D><Y><L><C><F><L><G><V><L><A><D><A><Q><R><L><S><L><L><P><E><V><A><G><L><Y><E><H><L><R><A><E><A><E><H><V><V><K><A...
This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.<BOP>
B2SQB3
Q0MQF8
NDUC2_GORGO
NADH-ubiquinone oxidoreductase subunit B14.5b
Gorilla
<M><I><A><R><R><N><P><E><P><L><R><F><L><P><D><E><A><R><S><L><P><P><P><K><L><T><D><P><R><L><L><Y><I><G><F><L><G><Y><C><S><G><L><I><D><N><L><I><R><R><R><P><I><A><T><A><G><L><H><R><Q><L><L><Y><I><T><A><F><F><F><A><G><Y><Y><L><V><K><R><E><D><Y><L><Y><A><V><R><D><R><E><M><F><G><Y><M><K><L><H><P><E><D><F><P><E><E><D><K><K><T...
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis but required for the complex assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is...
Q0MQF8