accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
2.3k
function
stringlengths
11
1.34k
AlphaFoldDB
stringlengths
6
10
O69540
IPYR_MYCLE
Pyrophosphate phospho-hydrolase
Mycobacterium
<M><Q><F><D><V><T><I><E><I><P><K><G><Q><R><N><K><Y><E><V><D><H><K><T><G><R><V><R><L><D><R><Y><L><Y><T><P><M><A><Y><P><T><D><Y><G><F><I><E><D><T><L><G><E><D><G><D><P><L><D><A><L><V><L><L><P><E><P><L><F><P><G><V><L><V><E><A><R><P><V><G><M><F><R><M><V><D><E><H><G><G><D><D><K><V><L><C><V><P><V><N><D><H><R><W><D><H><I><H><G...
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.<BOP>
O69540
A4XKX8
GUAA_CALS8
Glutamine amidotransferase
Caldicellulosiruptor
<M><Q><H><E><I><V><I><V><L><D><F><G><G><Q><Y><N><Q><L><I><A><R><R><V><R><E><C><G><V><Y><C><E><I><W><P><Y><D><T><P><L><E><K><I><I><E><K><N><P><K><G><I><I><F><T><G><G><P><S><S><V><Y><E><E><N><A><P><V><V><D><K><K><I><F><E><I><G><V><P><I><L><G><I><C><Y><G><N><Q><L><I><A><Y><F><L><G><G><K><V><S><T><A><L><F><R><E><Y><G><K><T...
Catalyzes the synthesis of GMP from XMP.<BOP>
A4XKX8
A7HZL3
RL16_CAMHC
50S ribosomal protein L16
Campylobacter
<M><L><M><P><K><K><T><K><Y><S><K><M><M><K><G><R><N><R><G><Y><A><V><R><G><I><K><L><N><F><G><D><Y><G><I><K><A><V><E><A><G><R><I><N><S><N><Q><I><E><A><A><R><I><A><M><T><R><Y><V><N><R><E><A><K><V><W><I><N><V><F><P><D><K><P><L><T><K><K><P><L><Q><T><R><M><G><K><G><K><T><G><V><E><E><W><V><M><N><I><K><P><G><R><I><I><F><E><L><T...
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP>
A7HZL3
P05452
TETN_HUMAN
Plasminogen kringle 4-binding protein
Homo
<M><E><L><W><G><A><Y><L><L><L><C><L><F><S><L><L><T><Q><V><T><T><E><P><P><T><Q><K><P><K><K><I><V><N><A><K><K><D><V><V><N><T><K><M><F><E><E><L><K><S><R><L><D><T><L><A><Q><E><V><A><L><L><K><E><Q><Q><A><L><Q><T><V><C><L><K><G><T><K><V><H><M><K><C><F><L><A><F><T><Q><T><K><T><F><H><E><A><S><E><D><C><I><S><R><G><G><T><L><G><T...
Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis.<BOP>
P05452
B5ZY62
APT_RHILW
Adenine phosphoribosyltransferase
Rhizobium
<M><D><K><N><T><T><S><E><L><A><A><S><I><R><S><I><P><D><Y><P><K><P><G><I><I><F><R><D><I><T><T><L><L><G><N><P><R><A><F><R><R><A><V><D><E><L><V><Q><P><Y><A><G><T><K><I><D><K><I><A><G><M><E><A><R><G><F><I><L><G><G><A><V><A><H><Q><L><S><S><G><F><V><P><I><R><K><K><G><K><L><P><H><E><T><V><R><I><A><Y><S><L><E><Y><G><V><D><E><M...
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.<BOP>
B5ZY62
P62647
CHEB_METMP
Protein-glutamate methylesterase/protein-glutamine glutaminase
Methanococcus
<M><S><K><I><K><V><L><I><V><D><D><S><A><F><M><R><K><V><L><E><D><I><L><K><S><D><D><E><I><E><V><V><A><T><A><K><D><G><K><E><A><F><E><L><V><K><K><L><E><P><N><V><I><T><M><D><V><E><M><P><I><M><N><G><I><D><A><T><K><Q><I><M><A><Y><K><P><T><P><I><L><M><L><S><A><V><T><K><Q><G><S><E><A><T><L><K><A><L><D><N><G><A><V><D><F><I><E><K...
Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deam...
P62647
Q03190
CXA4_RAT
Connexin-37
Rattus
<M><G><D><W><G><F><L><E><K><L><L><D><Q><V><Q><E><H><S><T><V><V><G><K><I><W><L><T><V><L><F><I><F><R><I><L><I><L><G><L><A><G><E><S><V><W><G><D><E><Q><S><D><F><E><C><N><T><A><Q><P><G><C><T><N><V><C><Y><D><Q><A><F><P><I><S><H><I><R><Y><W><V><L><Q><F><L><F><V><S><T><P><T><L><I><Y><L><G><H><V><I><Y><L><S><R><R><E><E><R><L><R...
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.<BOP>
Q03190
P0DKM4
TU25_LOPOL
OL25
Iotyrris
<S><L><V><C><D><L><E><C><S><A><E><V><T><T><C><C><E><T><G><T><C><H><G><I><T><T><Y><N><C><V><G><G><T><E><P><E><T>
Acts as a neurotoxin by inhibiting an ion channel.<BOP>
P0DKM4
Q0BQY5
ATPF1_GRABC
F-type ATPase subunit b 1
Granulibacter
<M><L><L><G><T><V><V><T><V><L><S><T><L><P><A><I><A><Y><A><M><D><P><E><S><P><E><H><E><G><M><P><Q><L><N><F><A><N><P><L><T><T><S><Q><V><V><W><M><A><L><I><L><L><A><F><Y><L><L><L><S><K><W><A><L><P><Q><V><S><Q><V><V><D><D><R><N><A><S><I><M><G><D><L><D><S><A><H><L><A><K><A><E><A><N><A><A><V><E><E><M><N><D><A><I><R><R><A><N><L...
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).<BOP>
Q0BQY5
Q9Y8K3
MTRB_METBF
N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit B
Methanosarcina
<M><S><M><I><R><I><A><P><E><L><N><L><V><M><D><P><E><T><G><T><I><T><Q><E><R><K><D><S><I><Q><Y><S><M><E><P><V><F><E><R><V><D><K><L><D><A><I><A><D><D><L><V><N><S><L><S><P><S><N><P><L><L><N><S><W><P><G><R><E><N><T><S><Y><M><A><G><F><Y><G><N><T><F><Y><G><V><I><I><G><L><A><F><S><G><L><L><A><L><V><I><Y><I><A><S><L><M><R><G><V...
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.<BOP>
Q9Y8K3
C4L3F5
EX7L_EXISA
Exodeoxyribonuclease VII large subunit
unclassified Exiguobacterium
<M><A><N><P><L><P><V><S><E><V><V><R><Y><V><K><R><Q><L><D><D><D><V><L><L><R><Q><V><A><V><I><G><E><I><S><N><F><K><R><Y><S><S><G><H><C><Y><F><T><L><K><D><D><A><S><R><M><K><A><V><M><F><S><R><D><A><K><Q><L><Q><F><E><P><K><D><G><M><K><V><I><A><V><S><K><V><T><M><Y><E><A><T><G><D><V><Q><L><Y><V><E><L><M><R><Q><D><G><I><G><L><L...
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.<BOP>
C4L3F5
Q7WH65
NAGZ_BORBR
N-acetyl-beta-glucosaminidase
Bordetella
<M><S><S><K><K><K><T><K><P><V><L><P><P><G><P><V><M><V><D><V><A><G><T><T><L><T><K><D><E><K><R><R><L><R><N><P><L><V><G><G><V><I><L><F><A><R><N><F><T><D><R><R><Q><L><C><A><L><T><R><A><I><H><K><A><R><K><E><P><L><L><I><A><V><D><H><E><G><G><R><V><Q><R><F><R><D><D><G><F><T><A><L><P><P><M><Q><E><L><G><K><L><W><D><R><D><P><L><A...
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.<BOP>
Q7WH65
C6E524
PSD_GEOSM
Phosphatidylserine decarboxylase beta chain
unclassified Geobacter
<M><R><N><T><D><T><P><I><A><V><E><G><Y><P><F><I><A><G><F><A><A><A><T><L><L><L><A><L><L><G><Q><F><L><H><L><G><F><F><V><P><A><T><L><F><F><V><L><T><V><F><T><V><F><F><F><R><N><P><E><R><V><T><P><G><D><E><N><T><V><V><A><P><A><D><G><E><V><I><F><L><G><K><V><I><E><P><H><T><N><G><E><F><E><K><I><S><I><F><M><S><V><F><N><V><H><V><N...
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).<BOP>
C6E524
O18211
MO25M_CAEEL
MO25-like protein 2
Caenorhabditis
<M><L><K><P><L><F><G><K><A><D><K><T><P><A><D><V><V><K><N><L><R><D><A><L><L><V><I><D><R><H><G><T><N><T><S><E><R><K><V><E><K><A><I><E><E><T><A><K><M><L><A><L><A><K><T><F><I><Y><G><S><D><A><N><E><P><N><N><E><Q><V><T><Q><L><A><Q><E><V><Y><N><A><N><V><L><P><M><L><I><K><H><L><H><K><F><E><F><E><C><K><K><D><V><A><S><V><F><N><N...
Regulates asymmetric cell division in Q.p neuroblast lineage . Plays a role in cell shedding during embryogenesis .<BOP>
O18211
A0QKZ7
RL6_MYCA1
50S ribosomal protein L6
Mycobacterium avium complex (MAC)
<M><S><R><I><G><K><Q><P><V><P><V><P><A><G><V><D><V><T><I><D><G><Q><K><V><S><V><K><G><P><K><G><T><L><D><L><T><V><A><E><P><I><T><V><S><R><N><D><D><G><A><I><V><V><T><R><P><N><D><E><R><R><N><R><S><L><H><G><L><S><R><T><L><V><S><N><L><V><T><G><V><T><Q><G><Y><T><T><K><M><E><I><F><G><V><G><Y><R><V><Q><L><K><G><S><N><L><E><F><A...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
A0QKZ7
Q0TJT3
6PGL_ECOL5
6-phosphogluconolactonase
Escherichia
<M><K><Q><T><V><Y><I><A><S><P><E><S><Q><Q><I><H><V><W><N><L><N><H><E><G><A><L><T><L><T><Q><V><V><D><V><P><G><Q><V><Q><P><M><V><V><S><P><D><K><R><Y><L><Y><V><G><V><R><P><E><F><R><V><L><A><Y><R><I><A><P><D><D><G><A><L><T><F><A><A><E><S><A><L><P><G><S><P><T><H><I><S><T><D><H><Q><G><Q><F><V><F><V><G><S><Y><N><A><G><N><V><S...
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.<BOP>
Q0TJT3
P43221
TLPA_BRADU
Cytochrome c biogenesis protein TlpA
Bradyrhizobium
<M><L><D><T><K><P><S><A><T><R><R><I><P><L><V><I><A><T><V><A><V><G><G><L><A><G><F><A><A><L><Y><G><L><G><L><S><R><A><P><T><G><D><P><A><C><R><A><A><V><A><T><A><Q><K><I><A><P><L><A><H><G><E><V><A><A><L><T><M><A><S><A><P><L><K><L><P><D><L><A><F><E><D><A><D><G><K><P><K><K><L><S><D><F><R><G><K><T><L><L><V><N><L><W><A><T><W><C...
Involved in cytochrome aa3 assembly.<BOP>
P43221
C6AQU6
TRMA_AGGAN
tmRNA (uracil(341)-C(5))-methyltransferase
Aggregatibacter
<M><Q><N><L><P><V><T><H><Y><S><A><L><L><A><E><K><Q><E><K><L><T><A><L><L><A><P><F><N><A><P><N><L><Q><V><F><A><S><P><T><Q><H><F><R><M><R><A><E><F><R><I><W><H><E><G><D><D><F><Y><H><I><M><F><D><Q><Q><S><K><Q><R><Y><R><V><D><N><F><P><I><A><S><E><L><I><N><R><M><M><T><A><L><L><P><L><L><K><Q><Q><T><V><L><H><H><R><L><F><Q><I><D...
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).<BOP>
C6AQU6
Q2QW55
MAD33_ORYSJ
OsMADS33
Oryza sativa
<M><V><R><G><K><V><Q><M><R><R><I><E><N><P><V><H><R><Q><V><T><F><C><K><R><R><G><G><L><L><K><K><A><R><E><L><S><V><L><C><D><A><D><V><G><V><I><I><F><S><S><Q><G><K><L><H><E><L><A><T><N><G><N><M><H><N><L><V><E><R><Y><Q><S><N><V><A><G><G><Q><M><E><P><G><A><L><Q><R><Q><Q><V><A><E><Q><G><I><F><L><L><R><E><E><I><D><L><L><Q><R><G...
Probable transcription factor.<BOP>
Q2QW55
Q5RF97
BCD1_PONAB
Zinc finger HIT domain-containing protein 6
Pongo
<M><E><F><A><A><E><N><E><G><K><S><G><G><G><L><H><S><V><A><E><G><V><R><L><S><P><E><P><G><R><E><G><V><R><D><L><A><G><A><E><E><F><G><G><G><E><E><G><K><G><L><T><G><V><K><E><I><G><D><G><E><E><G><S><R><Q><R><P><E><E><I><P><M><D><L><T><V><V><K><Q><E><I><I><D><W><P><G><T><E><G><R><L><A><G><Q><W><V><E><Q><E><V><E><D><R><P><E><V...
Required for box C/D snoRNAs accumulation involved in snoRNA processing, snoRNA transport to the nucleolus and ribosome biogenesis.<BOP>
Q5RF97
Q3ALC4
CLPP3_SYNSC
Endopeptidase Clp 3
unclassified Synechococcus
<M><P><I><G><T><P><S><V><P><Y><R><L><P><G><S><Q><M><E><R><W><V><D><I><Y><T><R><L><G><V><E><R><I><L><F><L><G><S><E><V><N><D><G><I><A><N><S><L><V><A><Q><M><L><Y><L><D><S><E><D><S><S><K><P><I><Y><L><Y><I><N><S><P><G><G><S><V><T><A><G><L><A><I><Y><D><T><I><Q><Y><V><K><S><E><V><V><T><I><C><V><G><L><A><A><S><M><G><A><F><L><L...
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.<BOP>
Q3ALC4
Q3UEZ8
NTCP4_MOUSE
Solute carrier family 10 member 4
Mus
<M><D><S><L><D><N><T><T><L><L><L><A><P><S><S><L><L><P><D><N><L><T><L><S><P><N><A><G><S><P><S><A><S><T><L><S><P><L><A><V><T><S><S><P><G><P><G><L><S><L><A><P><S><P><S><I><G><F><S><P><E><A><T><P><T><P><E><P><T><S><S><S><L><T><V><G><V><A><G><Q><G><S><S><A><F><P><R><P><W><I><P><H><E><P><P><F><W><D><T><P><L><N><H><G><L><N><V...
Transporter for bile acids.<BOP>
Q3UEZ8
A4IR71
GREA_GEOTN
Transcript cleavage factor GreA
Geobacillus
<M><A><N><E><K><Q><Y><P><M><T><K><E><G><K><E><K><L><E><Q><E><L><E><Y><L><K><T><V><K><R><K><E><V><V><E><R><I><K><I><A><R><G><F><G><D><L><S><E><N><S><E><Y><D><A><A><K><D><E><Q><A><F><V><E><S><R><I><Q><M><L><E><T><M><I><R><N><A><V><I><I><E><E><D><K><E><N><P><D><V><V><S><L><G><K><S><V><T><F><I><E><L><P><D><G><E><E><E><T><Y...
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factor...
A4IR71
B8CMW5
ISCS_SHEPW
Cysteine desulfurase IscS
Shewanella
<M><K><L><P><I><Y><L><D><Y><A><A><T><T><P><V><D><P><R><V><A><E><K><M><M><Q><C><M><T><M><D><G><I><F><G><N><P><A><S><R><S><H><R><Y><G><W><Q><A><E><E><A><V><D><I><A><R><N><Q><I><A><E><L><I><N><A><D><P><R><E><I><V><F><T><S><G><A><T><E><S><D><N><L><A><I><K><G><V><A><H><F><Y><Q><K><K><G><K><H><I><I><T><S><K><T><E><H><K><A><V...
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assemb...
B8CMW5
Q7NWP4
SYE_CHRVO
Glutamyl-tRNA synthetase
Chromobacterium
<M><I><R><T><R><F><A><P><S><P><T><G><Y><L><H><I><G><G><V><R><T><A><L><F><S><W><A><Y><A><R><K><N><N><G><V><F><V><L><R><I><E><D><T><D><L><E><R><S><T><P><E><S><V><K><A><I><L><D><G><M><H><W><V><G><L><D><Y><D><E><G><P><F><Y><Q><T><H><R><F><D><R><Y><K><E><V><I><Q><Q><L><L><D><S><G><H><A><Y><H><C><Y><C><S><K><E><E><L><E><A><M...
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP>
Q7NWP4
O08850
RGS5_MOUSE
Regulator of G-protein signaling 5
Mus
<M><C><K><G><L><A><A><L><P><H><S><C><L><E><R><A><K><E><I><K><I><K><L><G><I><L><L><Q><K><P><D><S><A><V><D><L><V><I><P><Y><N><E><K><P><E><K><P><A><K><A><H><K><P><S><L><E><E><V><L><Q><W><R><Q><S><L><D><K><L><L><Q><N><S><Y><G><F><A><S><F><K><S><F><L><K><S><E><F><S><E><E><N><L><E><F><W><V><A><C><E><N><Y><K><K><I><K><S><P><I...
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.<BOP>
O08850
Q8MUF4
CECB_ANOGA
Cecropin-B
Anopheles
<M><N><F><T><K><L><F><I><L><V><A><I><A><V><L><V><V><V><G><V><Q><P><V><D><G><A><P><R><W><K><F><G><K><R><L><E><K><L><G><R><N><V><F><R><A><A><K><K><A><L><P><V><I><A><G><Y><K><A><L><G>
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.<BOP>
Q8MUF4
Q5X8X9
LPXD1_LEGPA
UDP-3-O-acylglucosamine N-acyltransferase 1
Legionella
<M><N><S><S><L><R><D><I><A><N><L><V><Q><G><M><V><I><G><N><D><A><I><T><V><S><T><L><S><P><I><D><N><I><L><P><G><S><L><V><F><A><E><G><E><D><N><I><K><L><A><E><N><S><E><A><A><A><I><L><I><G><Q><G><T><I><D><S><P><K><P><L><I><Q><V><K><N><P><F><K><A><F><I><A><L><L><N><H><F><Y><P><P><R><R><I><S><P><G><V><H><P><T><A><V><I><G><A><E...
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP>
Q5X8X9
Q48KR3
ZIPA_PSE14
Cell division protein ZipA
Pseudomonas
<M><E><I><G><L><R><E><W><L><I><V><I><G><I><I><V><I><A><G><I><L><F><D><G><W><R><R><M><R><G><S><K><G><K><L><K><F><R><L><D><R><S><F><S><N><L><P><D><E><E><E><T><T><S><A><E><V><L><G><P><P><R><V><L><D><T><H><K><E><P><Q><L><D><E><H><D><L><P><S><M><S><A><S><P><R><E><G><K><R><S><N><S><D><K><R><G><N><S><D><K><K><R><K><D><E><P><Q...
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.<BOP>
Q48KR3
P40161
RT106_YEAST
Regulator of Ty1 transposition protein 106
Saccharomyces
<M><S><K><L><F><L><D><E><L><P><E><S><L><S><R><K><I><G><T><V><V><R><V><L><P><S><S><L><E><I><F><E><E><L><Y><K><Y><A><L><N><E><N><S><N><D><R><S><G><R><H><K><K><P><R><I><D><V><S><S><D><L><L><K><T><D><E><I><S><E><T><N><T><I><F><K><L><E><G><V><S><V><L><S><P><L><R><K><K><L><D><L><V><F><Y><L><S><N><V><D><G><S><P><V><I><T><L><L...
Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by directly recruiting the SWI/SNF and RSC ch...
P40161
Q9MV56
MATK_CEDAT
Intron maturase
Cedrus
<M><D><E><F><H><R><Y><G><K><E><D><S><S><W><Q><Q><C><F><L><Y><P><L><F><F><Q><E><D><L><Y><A><I><S><H><D><H><Y><L><D><G><S><S><S><S><E><P><M><E><H><F><S><F><N><D><Q><L><S><F><L><T><V><K><R><L><I><G><R><I><R><E><Q><N><H><S><I><G><L><F><V><N><C><D><P><N><P><L><V><D><R><N><K><S><S><Y><F><E><S><V><L><E><G><L><T><L><V><L><E><V...
Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns.<BOP>
Q9MV56
B5X582
TWIH_ARATH
DNA primase
Arabidopsis
<M><R><F><L><L><R><L><P><Q><I><H><F><R><K><L><S><C><S><M><S><V><L><M><G><S><K><Q><F><L><E><F><C><L><L><P><S><F><A><S><Y><P><S><S><P><S><Y><S><S><S><R><Q><V><S><S><V><S><R><R><F><R><P><V><L><A><S><R><P><V><S><K><N><S><P><Y><Y><Q><R><T><N><G><L><S><S><Y><N><S><I><P><R><V><P><T><P><V><D><T><E><V><E><A><D><K><R><V><V><L><S...
Has both DNA primase and DNA helicase activities and may be involved in organelle DNA replication. Capable of producing RNA primers of 9 to 18 bases from a single-stranded DNA template.<BOP>
B5X582
P38819
ERP5_YEAST
Protein ERP5
Saccharomyces
<M><K><Y><N><I><V><H><G><I><C><L><L><F><A><I><T><Q><A><V><G><A><V><H><F><Y><A><K><S><G><E><T><K><C><F><Y><E><H><L><S><R><G><N><L><L><I><G><D><L><D><L><Y><V><E><K><D><G><L><F><E><E><D><P><E><S><S><L><T><I><T><V><D><E><T><F><D><N><D><H><R><V><L><N><Q><K><N><S><H><T><G><D><V><T><F><T><A><L><D><T><G><E><H><R><F><C><F><T><P...
Involved in vesicular protein trafficking.<BOP>
P38819
P01624
KV315_HUMAN
Ig kappa chain V-III region POM
Homo
<M><E><A><P><A><Q><L><L><F><L><L><L><L><W><L><P><D><T><T><G><E><I><V><M><T><Q><S><P><A><T><L><S><V><S><P><G><E><R><A><T><L><S><C><R><A><S><Q><S><V><S><S><N><L><A><W><Y><Q><Q><K><P><G><Q><A><P><R><L><L><I><Y><G><A><S><T><R><A><T><G><I><P><A><R><F><S><G><S><G><S><G><T><E><F><T><L><T><I><S><S><L><Q><S><E><D><F><A><V><Y><Y...
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as recep...
P01624
Q0SQE5
RL4_CLOPS
50S ribosomal protein L4
Clostridium
<M><P><K><V><G><L><F><N><K><E><G><Q><Q><V><G><D><I><Q><L><N><E><Q><V><F><G><V><E><V><N><K><Y><A><L><H><Q><V><V><V><A><Q><L><A><N><K><R><Q><G><T><Q><S><A><K><T><R><S><E><V><R><G><G><G><I><K><P><W><R><Q><K><G><T><G><R><A><R><Q><G><S><I><R><A><P><Q><W><I><K><G><G><V><V><F><A><P><K><P><R><D><Y><R><M><S><I><P><K><S><M><R><K...
Forms part of the polypeptide exit tunnel.<BOP>
Q0SQE5
P20897
VM1H2_CRORU
Ruberlysin
Crotalus
<Q><N><L><P><Q><S><Y><I><E><L><V><V><V><A><D><H><R><M><F><M><K><Y><N><S><D><L><N><T><I><R><T><R><V><H><E><I><V><N><F><I><N><E><F><Y><R><S><L><N><I><R><V><S><L><T><D><L><E><I><W><S><D><Q><D><F><I><T><V><Q><S><S><A><K><N><T><L><H><S><F><G><E><W><R><K><S><V><L><L><N><R><K><R><H><D><N><A><Q><L><L><T><A><I><V><L><D><D><Y><T...
This protein is a zinc protease from snake venom that induces hemorrhage.<BOP>
P20897
A8HS37
RLMH_AZOC5
rRNA (pseudouridine-N3-)-methyltransferase RlmH
Azorhizobium
<M><R><V><L><L><I><C><V><G><R><L><K><A><G><A><E><R><E><L><V><T><R><Y><L><D><R><A><K><A><G><G><R><A><L><G><L><S><G><F><D><T><I><E><L><S><E><S><A><A><R><R><P><E><D><R><M><A><E><E><G><Q><A><I><L><G><A><L><P><Q><G><A><D><V><I><A><L><D><P><R><G><K><N><L><T><S><E><A><F><A><E><R><V><R><T><G><R><D><G><G><R><P><A><A><A><F><L><I...
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.<BOP>
A8HS37
Q5YZX1
HRCA_NOCFA
Heat-inducible transcription repressor HrcA
Nocardia
<M><G><P><M><S><S><S><T><E><D><R><R><F><E><V><L><R><A><I><V><A><D><Y><V><A><T><K><E><P><I><G><S><K><T><L><V><E><R><H><N><L><G><V><S><S><A><T><V><R><N><D><M><A><V><L><E><A><E><G><Y><I><T><Q><P><H><T><S><S><G><R><I><P><T><D><K><G><Y><R><Q><F><V><D><R><I><S><E><V><K><P><L><S><A><A><E><R><R><A><I><L><Q><F><L><E><S><G><V><D...
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.<BOP>
Q5YZX1
Q0HXV7
LIPA_SHESR
Sulfur insertion protein LipA
Shewanella
<M><N><R><P><E><R><L><Q><P><G><V><K><L><R><D><A><D><K><V><S><R><I><P><V><K><I><V><P><S><E><R><E><T><M><L><R><K><P><D><W><L><R><V><K><L><P><A><S><N><Q><R><I><L><E><I><K><Q><A><L><R><S><N><G><L><H><S><V><C><E><E><A><S><C><P><N><L><A><E><C><F><N><H><G><T><A><T><F><M><I><L><G><A><I><C><T><R><R><C><P><F><C><D><V><A><H><G><R...
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP>
Q0HXV7
Q8WT57
FAR1_ONCOC
Oo-FAR-1
Onchocerca
<M><Y><H><Q><L><I><L><M><A><L><I><G><V><I><M><A><N><V><V><P><F><S><M><S><N><I><P><E><E><Y><K><E><F><I><P><E><E><V><K><N><F><Y><K><N><L><T><Q><E><D><R><Q><I><L><R><E><L><A><S><K><H><A><T><F><T><N><E><D><A><A><L><E><A><L><K><N><K><S><D><K><L><Y><Q><K><A><V><E><L><R><N><F><V><K><A><K><I><D><S><L><K><P><D><A><K><A><F><V><D...
Binds retinol and different fatty acids.<BOP>
Q8WT57
Q47UW3
EFG2_COLP3
Elongation factor G 2
Colwellia
<M><A><R><I><T><P><I><E><R><Y><R><N><I><G><I><C><A><H><V><D><A><G><K><T><T><T><T><E><R><V><L><F><Y><T><G><L><S><H><K><I><G><E><V><H><D><G><A><A><T><M><D><W><M><E><Q><E><Q><E><R><G><I><T><I><T><S><A><A><T><T><C><F><W><K><G><M><E><G><Q><F><E><D><H><R><I><N><I><I><D><T><P><G><H><V><D><F><T><I><E><V><E><R><S><L><R><V><L><D...
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respective...
Q47UW3
G1CWH0
CYC1_CLITE
Cliotide T1
Clitoria
<G><I><P><C><G><E><S><C><V><F><I><P><C><I><T><G><A><I><G><C><S><C><K><S><K><V><C><Y><R><N><H><V><I><A><A><E><A><K><T><M><D><D><H><H><L><L><C><Q><S><H><E><D><C><I><T><K><G><T><G><N><F><C><A><P><F><P><D><Q><D><I><K><Y><G><W><C><F><R><A><E><S><E><G><F><M><L><K><D><H><L><K><M><S><I><T><N>
Probably participates in a plant defense mechanism (Probable). Active against Gram-negative bacteria E.coli ATCC 700926 (MIC=1.1 uM), K.pneumoniae ATTC 13883 (MIC=2.7 uM) and P.aeruginosa ATCC 39018 (MIC=4.7 uM) . Has hemolytic and cytotoxic activity .<BOP>
G1CWH0
Q25337
SIR2_LEIMA
SIR2-related protein 1
Leishmania
<M><T><G><S><P><R><A><P><H><Q><E><H><A><L><G><E><P><T><V><E><G><L><A><R><Y><I><R><E><K><D><V><R><R><I><L><V><L><V><G><A><G><A><S><V><A><A><G><I><P><D><F><R><S><S><D><T><G><I><Y><A><K><L><G><K><Y><N><L><D><D><P><T><D><A><F><S><L><T><L><L><R><E><K><P><E><I><F><Y><S><I><A><R><E><L><N><L><W><P><G><H><F><Q><P><T><A><V><H><H...
NAD-dependent deacetylase, which probably acts as a regulator of gene expression believed to help form modified chromatin structures on the genes it regulates.<BOP>
Q25337
P00155
CYF_PEA
Cytochrome f
Pisum
<M><Q><T><R><N><A><F><S><W><I><K><K><E><I><T><R><S><I><S><V><L><L><M><I><Y><I><I><T><R><A><P><I><S><N><A><Y><P><I><F><A><Q><Q><G><Y><E><N><P><R><E><A><T><G><R><I><V><C><A><N><C><H><L><A><N><K><P><V><D><I><E><V><P><Q><A><V><L><P><D><T><V><F><E><A><V><V><R><I><P><Y><D><M><Q><V><K><Q><V><L><A><N><G><K><K><G><A><L><N><V><G...
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.<BOP>
P00155
A9BE82
LGT_PROM4
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Prochlorococcus
<M><E><A><Y><F><A><T><F><R><S><P><G><P><E><L><L><K><V><G><F><F><T><L><R><W><Y><G><L><L><I><A><F><A><V><L><I><G><L><N><L><S><N><K><L><A><S><I><K><G><L><S><K><N><L><I><N><D><L><L><P><I><L><V><I><S><S><I><I><G><A><R><A><Y><Y><V><I><F><E><W><R><N><Y><S><G><S><N><F><W><S><S><I><Q><A><F><G><L><T><I><S><I><P><T><F><I><K><V><W...
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.<BOP>
A9BE82
Q2YDG2
CF299_BOVIN
Cilia- and flagella-associated protein 299
Bos
<M><D><Q><D><E><A><L><T><T><V><D><N><I><V><T><Q><F><N><T><Y><E><D><F><L><D><S><Q><I><T><T><L><D><L><Y><Y><L><E><D><E><G><L><A><R><Q><L><V><E><L><G><Y><R><G><T><G><E><V><V><K><R><E><D><F><E><A><R><K><A><A><I><E><I><A><R><L><A><E><R><T><Q><K><K><T><L><T><S><A><G><K><D><L><H><D><N><F><L><K><A><L><A><V><R><E><E><D><N><R><S...
May be involved in spermatogenesis.<BOP>
Q2YDG2
Q15326
ZMY11_HUMAN
Protein BS69
Homo
<M><A><R><L><T><K><R><R><Q><A><D><T><K><A><I><Q><H><L><W><A><A><I><E><I><I><R><N><Q><K><Q><I><A><N><I><D><R><I><T><K><Y><M><S><R><V><H><G><M><H><P><K><E><T><T><R><Q><L><S><L><A><V><K><D><G><L><I><V><E><T><L><T><V><G><C><K><G><S><K><A><G><I><E><Q><E><G><Y><W><L><P><G><D><E><I><D><W><E><T><E><N><H><D><W><Y><C><F><E><C><H...
(Microbial infection) Inhibits Epstein-Barr virus EBNA2-mediated transcriptional activation and host cell proliferation, through direct interaction.<BOP>
Q15326
A5F3G8
HSCA_VIBC3
Chaperone protein HscA homolog
Vibrio
<M><A><L><L><Q><I><A><E><P><G><Q><S><S><A><P><H><Q><H><K><L><A><A><G><I><D><L><G><T><T><N><S><L><V><A><S><V><R><S><G><T><A><S><T><L><V><D><S><Q><G><R><S><I><L><P><S><V><V><N><Y><G><A><D><A><T><R><V><G><Y><P><A><R><E><Q><A><E><T><D><P><H><N><T><V><I><S><V><K><R><L><L><G><R><S><L><Q><D><I><N><Q><R><Y><P><H><L><P><Y><R><F...
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.<BOP>
A5F3G8
A5CVH0
ARGC_VESOH
N-acetyl-glutamate semialdehyde dehydrogenase
Candidatus Vesicomyosocius
<M><I><K><V><G><I><I><G><S><T><G><Y><T><G><L><E><L><I><R><L><L><H><N><H><P><N><A><K><I><I><A><L><C><S><R><I><N><A><S><K><S><V><I><K><E><F><P><S><L><I><S><Y><I><D><L><D><F><V><T><P><N><E><K><K><L><F><E><C><D><I><I><F><F><A><T><P><H><G><V><A><M><N><S><V><S><K><F><L><N><K><D><I><K><I><I><D><L><G><A><D><F><R><I><K><D><S><T...
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.<BOP>
A5CVH0
Q08966
PCL8_YEAST
PHO85 cyclin-8
Saccharomyces
<M><A><N><D><Q><D><P><N><K><S><L><I><N><D><A><L><T><R><S><M><S><E><F><Y><D><D><D><D><D><N><D><S><D><M><C><R><A><N><D><E><G><E><D><V><F><D><L><P><L><K><V><G><V><S><Q><S><R><N><F><S><E><V><N><D><V><L><D><P><L><S><S><L><H><G><P><S><K><K><V><R><F><E><Q><Q><K><Q><Q><Q><Q><H><Q><Q><L><H><N><D><F><N><T><D><F><N><L><K><S><P><S...
Cyclin partner of the cyclin-dependent kinase (CDK) PHO85. Together with cyclin PCL10, negatively controls glycogen accumulation under favorable growth conditions. Involved in phosphorylation and negative regulation of glycogen synthase GSY2. Also has minor GLC8 kinase activity.<BOP>
Q08966
B1W3Z5
RL5_STRGG
50S ribosomal protein L5
Streptomyces
<M><T><A><T><T><A><P><R><L><K><T><R><Y><R><E><E><I><A><G><K><L><R><E><E><F><S><Y><E><N><V><M><Q><V><P><G><L><V><K><I><V><V><N><M><G><V><G><D><A><A><R><D><S><K><L><I><D><G><A><V><K><D><L><T><T><I><T><G><Q><K><P><A><V><T><K><A><R><K><S><I><A><Q><F><K><L><R><E><G><Q><P><I><G><C><H><V><T><L><R><G><D><R><M><W><E><F><L><D><R...
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement...
B1W3Z5
P21658
FGF6_MOUSE
Heparin-binding growth factor 6
Mus
<M><A><L><G><Q><R><L><F><I><T><M><S><R><G><A><G><R><V><Q><G><T><L><Q><A><L><V><F><L><G><V><L><V><G><M><V><V><P><S><P><A><G><A><R><A><N><G><T><L><L><D><S><R><G><W><G><T><L><L><S><R><S><R><A><G><L><A><G><E><I><S><G><V><N><W><E><S><G><Y><L><V><G><I><K><R><Q><R><R><L><Y><C><N><V><G><I><G><F><H><L><Q><V><P><P><D><G><R><I><S...
Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.<BOP>
P21658
P0A5J3
MAP1_MYCBO
Peptidase M
Mycobacterium tuberculosis complex
<M><P><S><R><T><A><L><S><P><G><V><L><S><P><T><R><P><V><P><N><W><I><A><R><P><E><Y><V><G><K><P><A><A><Q><E><G><S><E><P><W><V><Q><T><P><E><V><I><E><K><M><R><V><A><G><R><I><A><A><G><A><L><A><E><A><G><K><A><V><A><P><G><V><T><T><D><E><L><D><R><I><A><H><E><Y><L><V><D><N><G><A><Y><P><S><T><L><G><Y><K><G><F><P><K><S><C><C><T><S...
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.<BOP>
P0A5J3
Q2K9M8
RL11_RHIEC
50S ribosomal protein L11
Rhizobium
<M><A><K><K><V><A><G><Q><L><K><L><Q><V><K><A><G><S><A><N><P><S><P><P><I><G><P><A><L><G><Q><R><G><I><N><I><M><E><F><C><K><A><F><N><A><A><T><Q><E><M><E><K><G><M><P><I><P><V><V><I><T><Y><Y><Q><D><K><S><F><T><F><A><M><K><Q><P><P><V><S><Y><W><L><K><K><E><A><K><I><T><S><G><S><K><T><P><G><K><G><A><K><A><G><T><L><T><K><A><Q><I...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP>
Q2K9M8
O84746
YAJC_CHLTR
Sec translocon accessory complex subunit YajC
Chlamydia
<M><Y><S><R><L><F><F><S><I><L><F><F><L><G><C><C><P><A><L><F><A><D><T><D><S><P><Q><R><A><T><F><G><Q><P><A><V><M><L><G><I><A><I><V><F><F><Y><F><I><L><W><R><P><E><Q><K><R><R><Q><A><M><E><K><R><K><S><E><L><A><V><G><D><K><V><T><A><M><G><I><V><G><T><I><A><E><I><R><E><H><T><V><I><L><N><I><A><S><G><K><I><E><I><L><K><A><A><I><S...
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC s...
O84746
A6LQR9
OBG_CLOB8
GTP-binding protein Obg
Clostridium
<M><F><I><D><T><A><K><V><F><V><K><S><G><N><G><G><N><G><A><I><S><F><R><R><E><K><Y><V><P><L><G><G><P><D><G><G><D><G><G><K><G><G><S><I><I><F><Q><V><E><T><G><I><T><T><L><L><D><F><K><Y><K><K><K><F><I><A><E><S><G><E><N><G><G><G><S><K><C><Y><G><K><D><G><E><S><L><Y><I><K><V><P><M><G><T><I><I><R><E><A><E><T><N><K><I><I><A><D><L...
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B...
A6LQR9
P39009
DUN1_YEAST
DNA damage response protein kinase DUN1
Saccharomyces
<M><S><L><S><T><K><R><E><H><S><G><D><V><T><D><S><S><F><K><R><Q><Q><R><S><N><K><P><S><S><E><Y><T><C><L><G><H><L><V><N><L><I><P><G><K><E><Q><K><V><E><I><T><N><R><N><V><T><T><I><G><R><S><R><S><C><D><V><I><L><S><E><P><D><I><S><T><F><H><A><E><F><H><L><L><Q><M><D><V><D><N><F><Q><R><N><L><I><N><V><I><D><K><S><R><N><G><T><F><I...
Transducer of the DNA damage signal. Phosphorylates SML1 on serine residues. Cooperates with the PAN deadenylation complex in the regulation of RAD5 mRNA levels and cell survival in response to replicational stress.<BOP>
P39009
A0A287A2K5
GASR_PIG
Cholecystokinin-2 receptor
Sus
<M><E><L><L><K><L><N><R><S><L><P><G><P><G><P><G><A><A><L><C><R><P><E><G><P><L><L><N><G><S><G><A><G><N><L><S><C><E><P><P><R><I><R><G><A><G><T><R><E><L><E><L><A><V><R><I><T><L><Y><A><A><I><F><L><M><S><V><A><G><N><V><L><I><I><V><V><L><G><L><S><R><R><L><R><T><V><T><N><A><F><L><L><S><L><A><V><S><D><L><L><L><A><V><A><C><M><P...
Receptor for gastrin and cholecystokinin . The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity (Probable). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger ...
A0A287A2K5
B0TWU0
APT_FRAP2
Adenine phosphoribosyltransferase
Francisella
<M><N><L><D><F><I><K><D><R><I><V><A><V><P><D><F><P><K><P><G><I><V><F><R><D><I><T><P><L><L><A><D><P><Q><G><L><K><M><T><A><K><A><M><A><E><E><L><K><S><K><G><I><K><P><T><V><I><A><G><T><E><S><R><G><F><I><F><G><V><A><L><A><E><V><L><G><L><G><F><V><P><V><R><K><P><G><K><L><P><R><E><T><Y><K><V><S><Y><Q><L><E><Y><G><S><D><S><L><E...
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.<BOP>
B0TWU0
A8H779
NQRD_SHEPA
NQR-1 subunit D
Shewanella
<M><A><D><A><K><E><L><K><Q><V><L><I><G><P><I><V><S><N><N><P><I><A><L><Q><I><L><G><V><C><S><A><L><A><V><T><S><K><M><E><T><A><L><V><M><T><I><A><L><T><A><V><C><A><L><S><N><L><F><I><S><L><I><R><N><H><I><P><S><S><V><R><I><I><V><Q><M><T><I><I><A><S><L><V><I><V><V><D><Q><V><L><Q><A><Y><A><Y><D><V><A><K><Q><L><S><V><F><V><G><L...
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.<BOP>
A8H779
A5UDH0
TYSY_HAEIE
Thymidylate synthase
Haemophilus
<M><K><Q><Y><L><E><L><C><R><R><I><V><S><E><G><E><W><V><A><N><E><R><T><G><K><R><C><L><T><V><I><N><A><D><L><E><Y><D><V><A><N><N><Q><F><P><L><I><T><T><R><K><S><Y><W><K><A><A><I><A><E><F><L><G><Y><I><R><G><Y><D><N><A><A><D><F><R><A><L><G><T><K><T><W><D><A><N><A><N><E><N><A><A><W><L><A><N><P><H><R><R><G><V><D><D><M><G><R><V...
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell...
A5UDH0
A8ADP9
AROC_CITK8
5-enolpyruvylshikimate-3-phosphate phospholyase
Citrobacter
<M><A><G><N><T><L><G><Q><L><F><R><V><T><T><F><G><E><S><H><G><L><A><L><G><C><I><V><D><G><V><P><P><G><I><P><L><T><E><A><D><L><Q><H><D><L><D><R><R><R><P><G><T><S><R><Y><T><T><Q><R><R><E><P><D><Q><V><K><I><L><S><G><V><F><E><G><V><T><T><G><T><S><I><G><L><L><I><E><N><T><D><Q><R><S><Q><D><Y><S><A><I><K><D><V><F><R><P><G><H><A...
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s...
A8ADP9
Q7VQD5
RS14_BLOFL
30S ribosomal protein S14
Candidatus Blochmannia
<M><P><R><K><S><V><Q><E><R><E><K><K><R><L><R><L><I><N><K><Y><F><L><R><R><S><L><L><R><K><C><V><V><D><L><K><V><S><S><E><E><R><W><N><A><V><L><K><L><Q><T><L><P><R><D><S><S><P><S><R><L><R><N><R><C><G><R><T><G><R><P><H><A><F><L><R><K><F><G><L><S><R><M><K><V><R><E><A><A><M><K><G><E><I><P><G><L><R><K><S><S><W>
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.<BOP>
Q7VQD5
A1UG51
POTA_MYCSK
Spermidine/putrescine import ATP-binding protein PotA
unclassified Mycobacterium
<M><N><Q><T><V><D><G><V><A><P><N><K><S><G><P><V><I><E><I><D><H><V><T><K><R><F><A><D><Y><V><A><V><A><D><A><D><F><S><I><A><S><G><E><F><F><S><M><L><G><P><S><G><C><G><K><T><T><T><L><R><M><I><A><G><F><E><T><P><T><S><G><A><I><R><L><E><G><T><D><V><S><R><V><P><P><H><K><R><N><V><N><T><V><F><Q><H><Y><A><L><F><P><H><M><S><V><W><D...
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.<BOP>
A1UG51
A3D1S4
ANMK_SHEB5
AnhMurNAc kinase
Shewanella
<M><K><N><A><Y><Y><I><G><L><M><S><G><T><S><M><D><G><V><D><A><V><L><V><D><F><S><G><A><Q><P><Q><L><I><T><S><H><T><E><A><I><P><S><H><L><L><K><G><L><Q><R><L><C><S><P><S><T><D><E><I><N><R><L><G><R><L><D><R><N><V><G><E><L><F><A><L><A><V><N><N><L><L><T><K><C><A><I><A><K><E><D><V><I><A><I><G><S><H><G><Q><T><V><R><H><M><P><N><L...
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall ...
A3D1S4
P30778
RUBR_AZOVI
Rubredoxin
Azotobacter
<M><S><A><R><F><E><G><S><Y><L><G><D><A><T><R><L><A><D><D><A><V><L><E><C><K><I><C><W><Q><R><Y><D><P><A><E><G><D><P><V><W><Q><I><P><P><G><T><P><F><A><A><L><P><A><H><W><R><C><P><R><C><D><G><D><R><E><Q><F><M><V><V><D><G>
Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. Could be involved in hydrogenase-linked redox processes.<BOP>
P30778
Q47LK5
RL5_THEFY
50S ribosomal protein L5
Thermobifida
<M><T><V><T><N><E><I><D><A><P><P><I><P><R><L><K><Q><K><Y><R><E><E><I><I><P><A><L><R><E><E><F><G><Y><T><N><I><M><Q><V><P><G><L><T><K><I><V><V><N><M><G><V><G><D><A><A><R><D><A><K><L><I><Q><G><A><I><A><D><L><S><A><I><T><G><Q><K><P><K><I><N><R><A><K><K><S><I><A><Q><F><K><L><R><Q><G><Q><P><I><G><A><S><V><T><L><R><G><D><R><M...
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement...
Q47LK5
C3PKP2
EFTU_CORA7
Elongation factor Tu
Corynebacterium
<M><A><K><E><K><F><E><R><T><K><P><H><V><N><I><G><T><I><G><H><V><D><H><G><K><T><T><T><T><A><A><I><T><K><V><L><A><D><A><Y><P><E><E><N><T><A><F><A><F><D><M><I><D><K><A><P><E><E><K><E><R><G><I><T><I><N><I><S><H><V><E><Y><S><T><P><K><R><H><Y><A><H><V><D><A><P><G><H><A><D><Y><I><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V...
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP>
C3PKP2
A4TPN1
MTNC_YERPP
2,3-diketo-5-methylthio-1-phosphopentane phosphatase
Yersinia
<M><I><Q><A><I><V><T><D><I><E><G><T><T><T><D><I><R><F><V><H><Q><V><L><F><P><Y><A><R><E><R><L><T><P><F><L><R><A><H><Q><Q><D><D><D><I><A><A><L><L><V><D><L><R><R><E><I><A><Q><P><D><A><D><I><E><T><L><I><T><V><L><H><G><F><M><D><E><D><R><K><S><T><V><L><K><A><I><Q><G><I><I><W><R><T><G><Y><L><Q><A><D><F><R><G><H><V><Y><P><E><V...
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).<BOP>
A4TPN1
Q9GZL7
WDR12_HUMAN
WD repeat-containing protein 12
Homo
<M><A><Q><L><Q><T><R><F><Y><T><D><N><K><K><Y><A><V><D><D><V><P><F><S><I><P><A><A><S><E><I><A><D><L><S><N><I><I><N><K><L><L><K><D><K><N><E><F><H><K><H><V><E><F><D><F><L><I><K><G><Q><F><L><R><M><P><L><D><K><H><M><E><M><E><N><I><S><S><E><E><V><V><E><I><E><Y><V><E><K><Y><T><A><P><Q><P><E><Q><C><M><F><H><D><D><W><I><S><S><I...
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.<BOP>
Q9GZL7
A1USS3
RECA_BARBK
Recombinase A
Bartonella
<M><D><K><K><K><A><L><D><A><A><L><S><Q><I><E><R><S><F><G><K><G><S><I><M><R><L><G><Q><K><E><G><V><V><E><I><E><T><I><S><T><G><S><L><S><L><D><I><A><L><G><V><G><G><L><P><K><G><R><I><I><E><I><Y><G><P><E><S><S><G><K><T><T><L><A><L><H><A><I><A><E><A><Q><K><N><G><G><V><C><A><F><V><D><A><E><H><A><L><D><P><I><Y><A><R><K><L><G><V...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
A1USS3
O83822
IF3_TREPA
Translation initiation factor IF-3
Treponema
<M><Y><W><G><G><S><L><A><D><N><K><S><L><R><I><N><G><S><I><R><V><R><E><V><R><L><V><D><A><V><G><Q><Q><C><G><V><V><P><T><P><E><A><L><R><M><A><R><D><I><N><L><D><L><V><E><V><A><P><Q><A><S><P><P><V><C><K><I><L><D><Y><G><K><Y><R><F><E><M><G><K><K><L><R><D><S><K><K><R><Q><R><L><Q><T><L><K><E><V><R><M><Q><P><K><I><N><D><H><D><M...
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.<BOP>
O83822
Q3AFM4
ISPE_CARHZ
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase
Carboxydothermus
<M><L><I><F><A><P><A><K><I><N><L><T><L><D><I><L><G><K><R><P><D><G><Y><H><E><L><W><S><V><M><Q><A><I><T><L><G><D><L><V><E><I><E><P><A><E><G><I><N><L><R><V><V><G><A><D><L><P><V><D><S><T><N><I><A><F><K><A><V><Q><A><L><R><A><A><T><G><K><A><I><G><A><S><I><T><I><R><K><K><I><P><L><E><A><G><L><A><G><G><S><A><D><G><A><A><V><L><Y...
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.<BOP>
Q3AFM4
Q4QLA3
SUCC_HAEI8
Succinyl-CoA synthetase subunit beta
Haemophilus
<M><N><L><H><E><Y><Q><A><K><Q><L><F><E><H><Y><G><L><P><V><K><N><G><A><V><C><Q><S><V><E><D><V><D><L><V><L><A><Q><L><S><G><D><K><W><A><A><K><C><Q><V><H><A><G><G><R><G><K><A><G><G><V><K><L><V><Q><D><V><E><E><A><R><A><F><A><E><K><W><L><G><Q><R><L><V><T><F><Q><T><D><K><L><G><Q><P><V><N><Q><I><Y><F><E><E><T><C><D><I><D><K><E...
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinat...
Q4QLA3
Q9ZDY5
QUED_RICPR
Queuosine biosynthesis protein QueD
typhus group
<M><I><K><C><T><R><R><I><N><F><D><A><G><H><R><I><I><G><H><K><N><K><C><Q><F><L><H><G><H><H><Y><V><L><E><I><T><I><A><A><N><K><T><D><T><L><G><M><V><I><D><F><G><L><I><K><N><L><A><K><K><W><I><D><A><N><F><D><H><N><L><I><L><H><Q><D><D><K><E><M><G><Q><Q><I><E><N><Y><T><R><Q><K><I><Y><Y><M><R><N><N><P><T><A><E><N><I><A><T><H><L...
Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.<BOP>
Q9ZDY5
B8FKD5
DNLJ_DESAL
Polydeoxyribonucleotide synthase [NAD(+)]
Desulfatibacillum
<M><Q><D><L><P><S><S><I><A><D><I><S><D><P><E><L><L><G><Q><W><L><E><K><Y><N><E><A><Y><R><A><G><K><P><M><I><S><D><A><H><Y><D><L><L><V><E><R><L><R><E><I><A><P><D><H><G><F><L><S><A><V><E><A><E><T><F><A><D><K><R><E><V><R><H><P><A><P><M><L><S><T><E><K><A><Y><D><K><Q><S><L><E><R><F><V><E><R><V><Y><K><E><A><A><Q><I><G><V><T><D...
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP>
B8FKD5
C6E345
ACP_GEOSM
Acyl carrier protein
unclassified Geobacter
<M><A><S><I><E><K><R><I><K><E><I><V><A><E><Q><L><G><V><D><E><A><Q><V><T><N><E><S><S><F><M><D><D><L><G><A><D><S><L><D><T><V><E><L><V><M><A><L><E><E><E><F><E><I><E><I><S><D><E><D><A><E><K><I><Q><S><V><Q><D><A><I><D><Y><I><T><D><H><T>
Carrier of the growing fatty acid chain in fatty acid biosynthesis.<BOP>
C6E345
B4EAS0
Y800_BURCJ
Nucleotide-binding protein BceJ2315_08000
Burkholderia cepacia complex
<M><R><I><V><L><I><T><G><I><S><G><S><G><K><S><V><A><L><N><A><L><E><D><A><G><Y><Y><C><V><D><N><L><P><P><H><V><L><P><E><L><A><R><Y><L><A><Q><D><G><Q><R><R><L><A><V><A><I><D><A><R><S><S><A><S><L><D><E><M><P><G><L><I><R><E><L><S><R><E><H><D><V><R><V><L><F><L><N><A><S><T><Q><A><L><I><Q><R><F><S><E><T><R><R><R><H><P><L><S><G...
Displays ATPase and GTPase activities.<BOP>
B4EAS0
B8FPL1
SCPA_DESHD
Segregation and condensation protein A
Desulfitobacterium
<M><S><N><G><S><S><V><S><H><S><A><N><T><A><P><Y><V><E><L><P><A><F><Q><G><P><M><D><L><L><L><H><L><I><Q><Q><E><K><V><D><I><Y><D><I><P><I><A><R><I><T><D><Q><F><I><Q><V><V><R><Q><M><E><D><L><D><M><E><V><T><T><E><F><L><V><L><A><A><Q><L><L><Q><I><K><S><R><Y><L><L><P><K><P><V><K><D><V><T><V><E><E><E><G><D><P><R><Q><E><L><V><E...
Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.<BOP>
B8FPL1
Q5F8C0
GLYA_NEIG1
Serine hydroxymethyltransferase
Neisseria
<M><F><S><K><S><V><T><L><A><Q><Y><D><P><D><L><A><A><A><I><A><Q><E><D><R><R><Q><Q><D><H><V><E><L><I><A><S><E><N><Y><V><S><C><A><V><M><E><A><Q><G><S><Q><L><T><N><K><Y><A><E><G><Y><P><A><K><R><Y><Y><G><G><C><E><Y><V><D><I><V><E><Q><L><A><I><D><R><V><K><E><L><F><G><A><A><Y><A><N><V><Q><P><H><S><G><S><Q><A><N><Q><A><V><Y><A...
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a...
Q5F8C0
Q9D273
MMAB_MOUSE
Methylmalonic aciduria type B homolog
Mus
<M><A><V><W><L><F><G><G><R><L><G><L><R><G><R><L><S><A><C><R><L><L><C><P><R><F><Q><S><R><G><P><Q><G><G><E><D><G><D><R><L><Q><P><S><S><T><A><A><K><I><P><K><I><Y><T><K><T><G><D><K><G><F><S><S><T><F><T><G><E><R><R><P><K><D><D><Q><V><F><E><A><V><G><T><T><D><E><L><S><S><A><I><G><F><A><M><E><L><V><T><E><K><G><H><M><F><A><E><E...
Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion. Generates adenosylcobalamin (AdoCbl) and directly delivers the cofactor to MUT in a transfer that is stimulated by ATP-binding to MMAB and...
Q9D273
Q16DS2
BCHL_ROSDO
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein
Roseobacter
<M><S><P><L><D><R><T><P><P><S><L><R><G><Q><D><G><E><G><S><V><Q><V><H><Q><D><E><T><A><K><I><E><G><A><K><V><F><S><V><Y><G><K><G><G><I><G><K><S><T><T><S><S><N><L><S><A><A><F><S><M><L><G><K><R><V><L><Q><I><G><C><D><P><K><H><D><S><T><F><T><L><T><G><S><L><V><P><T><V><I><D><I><L><K><E><V><D><F><H><P><E><E><L><R><A><E><D><F><V...
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and ...
Q16DS2
Q02372
NDUB8_BOVIN
NADH-ubiquinone oxidoreductase ASHI subunit
Bos
<M><A><A><A><R><A><G><V><L><G><V><R><W><L><Q><K><A><A><R><N><V><V><P><L><G><A><R><T><A><S><H><I><T><K><D><M><L><P><G><P><Y><P><K><T><P><E><E><R><A><A><A><A><K><K><Y><N><M><R><V><E><D><Y><E><P><Y><P><D><D><G><T><G><Y><G><D><Y><P><K><L><P><D><R><S><Q><Q><E><R><D><P><W><Y><D><W><D><H><P><D><L><R><L><N><W><G><E><P><M><H><W...
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.<BOP>
Q02372
P0CB52
NANE_STRSU
ManNAc-6-P epimerase
Streptococcus
<M><G><K><I><S><K><E><A><L><K><E><Q><I><K><D><G><I><I><I><S><C><Q><A><L><P><G><E><P><L><Y><R><E><E><G><G><I><M><P><L><L><V><K><A><A><Q><E><A><G><A><V><G><I><R><A><N><S><V><R><D><I><K><E><I><K><E><V><T><T><L><P><I><I><G><I><I><K><R><D><Y><P><P><Q><E><P><F><I><T><A><T><M><R><E><V><D><E><L><A><A><L><D><I><E><V><I><A><L><D...
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).<BOP>
P0CB52
B7VKY2
CYSN_VIBA3
Sulfate adenylate transferase
Vibrio
<M><N><S><A><V><E><A><E><L><A><E><L><G><I><E><G><Y><L><S><Q><H><Q><H><K><S><M><L><R><F><L><T><C><G><S><V><D><D><G><K><S><T><L><I><G><R><L><L><H><D><T><K><Q><I><Y><E><D><Q><L><A><A><V><H><S><D><S><Q><R><V><G><T><T><G><E><K><P><D><L><A><L><L><V><D><G><L><Q><A><E><R><E><Q><G><I><T><I><D><V><A><Y><R><Y><F><S><T><Q><K><R><K...
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysi...
B7VKY2
Q65PM2
DNAA_BACLD
Chromosomal replication initiator protein DnaA
Bacillus
<M><K><N><I><S><D><L><W><N><Q><A><L><G><Q><I><E><K><K><L><S><K><P><S><F><E><T><W><M><K><S><T><K><A><H><S><L><Q><G><D><T><L><I><I><T><A><P><N><E><F><A><R><D><W><L><E><S><R><Y><L><H><L><I><A><D><T><I><Y><D><L><T><G><E><E><L><S><I><K><F><V><I><P><Q><N><Q><N><E><E><D><F><M><P><K><S><P><I><K><K><M><S><K><E><E><P><A><D><F><P...
Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.<BOP>
Q65PM2
Q8H186
PBL1_ARATH
Protein CHANGED CALCIUM ELEVATION 5
Arabidopsis
<M><G><S><C><L><S><S><R><V><L><N><K><S><S><S><G><L><D><D><L><H><L><S><S><C><K><S><S><S><S><A><T><A><H><K><T><E><G><E><I><L><S><S><T><T><V><K><S><F><S><F><N><E><L><K><L><A><T><R><N><F><R><S><D><S><V><V><G><E><G><G><F><G><C><V><F><R><G><W><L><D><E><T><T><L><T><P><T><K><S><S><S><G><L><V><I><A><V><K><R><L><N><P><D><G><F><Q...
Contributes to pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) signaling, including calcium signaling and root growth inhibition, and defense responses downstream of FLS2 . Acts additively with BIK1 in PTI defenses . Seems not required for flg22-induced MAPK activation (Probable). Required for Pep...
Q8H186
B0G172
PGTB2_DICDI
Type II protein geranyl-geranyltransferase subunit beta
Dictyostelium
<M><T><D><N><I><N><K><E><S><T><T><T><T><T><T><I><D><H><T><T><N><L><L><I><D><K><H><V><E><Y><I><V><K><L><G><S><K><K><D><S><F><E><Y><W><V><T><E><H><I><R><M><N><G><M><Y><W><G><L><S><S><L><Y><L><L><K><S><L><D><K><L><D><K><N><E><V><I><Q><W><L><L><S><C><Q><K><S><N><G><G><F><G><G><N><T><S><H><D><D><H><L><L><S><T><L><S><A><V><Q...
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal.<BOP>
B0G172
Q8MJ02
NCTR3_MACMU
Natural killer cell p30-related protein
Macaca
<M><A><W><M><L><L><L><I><L><I><M><V><Y><P><G><S><C><A><L><W><V><S><Q><P><P><E><I><R><T><L><E><G><S><S><A><F><L><P><C><S><F><N><A><S><Q><G><R><L><A><I><G><S><V><T><W><F><R><D><E><V><A><P><G><K><E><V><R><N><G><T><P><E><F><R><G><R><L><A><P><L><S><S><S><R><F><L><R><D><H><Q><A><E><L><H><I><W><D><V><R><G><H><D><A><G><I><Y><V...
Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also pro...
Q8MJ02
P49173
NIP1_NICAL
Pollen-specific membrane integral protein
Nicotiana
<M><A><K><K><D><G><N><Q><E><E><E><I><S><Q><M><E><E><G><N><I><H><S><A><S><N><S><D><S><N><V><G><F><C><S><S><V><S><V><V><V><I><L><Q><K><L><I><A><E><A><I><G><T><Y><F><V><I><F><A><G><C><G><S><V><A><V><N><K><I><Y><G><S><V><T><F><P><G><I><C><V><T><W><G><L><I><V><M><V><M><V><Y><T><V><G><Y><I><S><G><A><H><F><N><P><A><V><T><I><T...
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.<BOP>
P49173
P56363
RK14_CHLVU
50S ribosomal protein L14, chloroplastic
Chlorella
<M><I><Q><P><Q><T><Y><L><R><V><A><D><N><T><G><A><R><E><L><M><C><I><R><V><L><G><G><G><K><Q><R><A><A><T><V><G><D><I><I><I><A><V><V><K><D><A><T><P><N><M><P><V><K><R><S><D><I><V><R><A><V><I><V><R><T><R><K><N><V><R><R><V><N><G><T><S><I><R><F><D><E><N><A><A><V><I><I><N><K><E><N><N><P><R><G><T><R><V><F><G><P><V><A><R><E><L><R...
Binds to 23S rRNA.<BOP>
P56363
Q608N1
MIAB_METCA
tRNA-i(6)A37 methylthiotransferase
Methylococcus
<M><P><Q><K><L><Y><I><E><T><F><G><C><Q><M><N><E><Y><D><S><A><K><M><R><D><L><L><E><V><S><D><S><F><E><L><A><R><S><P><E><E><A><D><V><L><L><L><N><T><C><S><I><R><D><K><A><Q><E><K><V><F><S><Q><L><G><R><W><R><P><I><K><L><R><R><P><E><V><V><I><G><V><G><G><C><V><A><S><Q><E><G><E><A><L><Q><K><R><A><P><Y><V><D><I><V><F><G><P><Q><T...
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.<BOP>
Q608N1
Q2JTR0
TRMD_SYNJA
tRNA [GM37] methyltransferase
unclassified Synechococcus
<M><R><F><D><V><I><T><L><F><P><E><F><F><A><T><P><L><R><I><G><L><V><G><K><A><L><E><Q><G><I><A><E><V><H><C><T><N><P><R><D><F><A><T><D><K><H><R><R><V><D><D><E><P><Y><G><G><G><V><G><M><V><L><K><P><E><P><F><F><A><A><V><A><S><L><P><R><L><D><P><C><E><I><I><L><L><T><P><Q><G><Q><P><L><N><Q><A><L><L><Q><E><L><A><Q><K><A><Q><L><I...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
Q2JTR0
P11841
CASK_PIG
Kappa-casein
Sus
<M><M><K><S><S><F><L><I><V><P><I><L><A><L><T><L><P><F><L><G><A><E><E><Q><N><Q><E><K><L><T><R><C><E><S><D><K><R><L><F><N><E><E><K><V><K><Y><I><P><I><Y><Y><M><L><N><R><F><P><S><Y><G><F><F><Y><Q><H><R><S><A><V><S><P><N><R><Q><F><I><P><Y><P><Y><Y><A><R><P><V><V><A><G><P><H><A><Q><K><P><Q><W><Q><D><Q><P><N><V><Y><P><P><T><V...
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.<BOP>
P11841
A0KFN8
MEND_AERHH
Menaquinone biosynthesis protein MenD
Aeromonas
<M><S><A><R><Q><E><F><A><S><H><H><A><T><F><N><H><V><W><S><S><L><L><L><E><E><L><F><R><L><G><V><R><D><I><A><L><A><S><G><S><R><S><A><P><L><T><M><A><A><A><A><H><P><G><F><R><R><H><L><H><F><D><E><R><G><L><G><F><M><A><L><G><L><A><K><G><S><G><R><P><V><A><V><I><M><T><S><G><T><A><V><A><N><L><W><P><A><V><A><E><A><Q><L><T><G><V><P...
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).<BOP>
A0KFN8
B7GLA4
QUEC_ANOFW
Queuosine biosynthesis protein QueC
Anoxybacillus
<M><K><K><E><K><A><V><V><V><F><S><G><G><Q><D><S><T><T><C><L><F><W><A><K><K><H><F><A><E><V><E><A><V><T><F><D><Y><N><Q><R><H><R><L><E><I><D><V><A><A><S><I><A><K><E><L><N><V><S><H><T><V><L><D><M><S><L><L><H><Q><L><A><P><N><A><L><T><R><S><D><I><A><I><E><Q><K><E><G><Q><L><P><S><T><F><V><D><G><R><N><L><L><F><L><S><F><A><A><V...
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).<BOP>
B7GLA4
Q319F1
FABZ_PROM9
Beta-hydroxyacyl-ACP dehydratase
Prochlorococcus
<M><D><N><K><L><S><S><E><N><N><Q><L><S><S><E><K><I><L><G><L><L><P><H><R><Y><P><F><A><L><V><D><K><V><I><E><N><I><P><G><E><R><A><V><A><V><K><N><V><T><I><N><E><P><Q><F><Q><G><H><F><P><E><R><P><L><M><P><G><V><L><I><V><E><S><M><A><Q><V><G><G><I><I><V><T><Q><M><P><D><L><P><K><G><L><F><V><F><A><G><I><N><N><V><K><F><R><K><P><V...
Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.<BOP>
Q319F1
A1JNP6
CYOE_YERE8
Heme O synthase
Yersinia
<M><M><I><K><Q><Y><L><Q><V><T><K><P><G><I><I><F><G><N><L><I><S><V><V><G><G><F><L><L><A><S><K><G><V><I><D><Y><P><L><F><L><A><T><L><F><G><V><S><L><V><V><A><S><G><C><V><F><N><N><Y><I><D><R><D><I><D><R><I><M><E><R><T><K><N><R><V><L><V><K><G><L><I><D><P><K><V><S><L><I><Y><A><S><I><L><G><I><A><G><M><L><L><L><Y><V><G><A><N><P...
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.<BOP>
A1JNP6
Q9GZY6
NTAL_HUMAN
Williams-Beuren syndrome chromosomal region 5 protein
Homo
<M><S><S><G><T><E><L><L><W><P><G><A><A><L><L><V><L><L><G><V><A><A><S><L><C><V><R><C><S><R><P><G><A><K><R><S><E><K><I><Y><Q><Q><R><S><L><R><E><D><Q><Q><S><F><T><G><S><R><T><Y><S><L><V><G><Q><A><W><P><G><P><L><A><D><M><A><P><T><R><K><D><K><L><L><Q><F><Y><P><S><L><E><D><P><A><S><S><R><Y><Q><N><F><S><K><G><S><R><H><G><S><E...
Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors ...
Q9GZY6
Q6MTZ0
YQGF_MYCMS
Putative pre-16S rRNA nuclease
Mycoplasma
<M><T><Q><S><I><I><A><L><D><I><G><S><K><T><I><G><L><A><Y><S><S><G><V><I><A><S><S><L><D><T><I><R><F><E><E><Y><N><F><D><Q><G><L><R><Q><L><E><S><Y><L><K><K><Y><N><P><T><I><I><V><V><G><Y><P><K><N><M><N><N><T><I><G><E><R><A><E><M><V><D><Y><V><I><E><M><F><L><D><M><Y><K><N><F><N><K><D><Q><I><I><R><I><D><E><R><R><T><T><K><I><A...
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP>
Q6MTZ0