accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
F7ZLS5
HYEP_ROSLO
Hydrophobic dipeptide epimerase
Roseobacter
<M><K><V><E><Y><H><T><V><Y><L><K><K><R><F><P><L><R><I><S><R><G><V><F><E><G><S><D><N><L><Y><I><S><L><T><E><N><G><H><T><G><W><G><E><M><A><P><G><G><T><E><G><A><E><T><A><A><A><G><Q><A><M><L><E><Q><F><C><A><T><G><L><S><A><S><I><H><D><T><W><Q><N><A><H><A><A><G><V><A><P><C><A><L><A><A><L><D><M><A><L><W><D><L><R><A><K><Q><A><G...
Dipeptide epimerase with a preference for hydrophobic substrates. Catalyzes the epimerization of L-Ala-L-Thr, L-Ala-L-Met, L-Ala-L-His, L-Ala-L-Phe, L-Ala-L-Tyr, L-Ala-L-Trp, L-Ile-L-Ala, L-Ile-L-Ser, L-Ile-L-Met, L-Ile-L-His, L-Ile-L-Phe, L-Ile-L-Tyr, L-Ile-L-Trp, L-Phe-L-Met, L-Phe-L-His, L-Phe-L-Phe, L-Phe-L-Tyr, L-...
F7ZLS5
Q6CQP9
VMA21_KLULA
Vacuolar ATPase assembly integral membrane protein VMA21
Kluyveromyces
<M><P><V><D><V><P><R><S><V><I><A><K><L><M><F><F><T><V><A><M><V><V><L><P><V><L><T><F><F><W><L><Q><E><H><T><D><N><T><L><V><S><G><G><L><A><A><A><M><A><N><L><V><L><I><A><Y><V><I><M><A><F><Q><E><D><S><S><S><S><E><D><D><E><T><K><K><E><K>
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.<BOP>
Q6CQP9
Q46WT0
HEM1_CUPPJ
Glutamyl-tRNA reductase
Cupriavidus
<M><Q><L><L><A><I><G><I><N><H><T><T><A><P><V><S><L><R><E><R><V><A><F><P><L><E><Q><I><K><P><A><L><G><A><L><R><T><H><L><A><G><R><N><G><T><E><A><A><I><L><S><T><C><N><R><T><E><I><Y><C><A><T><D><I><L><K><P><G><A><E><G><F><E><H><T><L><R><W><L><S><Q><H><H><N><V><P><A><S><D><L><A><P><H><L><Y><S><L><P><Q><S><E><A><V><R><H><A><F...
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).<BOP>
Q46WT0
Q9HLV2
PCKG_THEAC
Phosphoenolpyruvate carboxykinase [GTP]
Thermoplasma
<M><L><A><I><D><E><S><E><L><N><Q><H><A><M><K><W><I><E><G><I><K><K><F><T><E><A><E><D><V><V><V><C><D><G><T><P><E><E><F><K><Q><I><S><N><E><L><I><K><S><G><E><F><I><K><L><N><E><N><R><Y><P><N><S><F><L><Y><R><S><D><R><T><D><V><A><R><S><E><E><R><T><F><I><A><A><P><D><A><S><M><A><G><S><L><N><N><H><M><T><L><Q><Q><V><S><E><V><W><N...
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.<BOP>
Q9HLV2
P47315
PTG3C_MYCGE
PTS system glucose-specific EIIA component
Mycoplasma
<M><Q><I><S><L><V><K><I><R><N><K><F><K><Q><R><N><R><G><S><F><R><Q><W><V><G><K><L><S><N><G><L><M><I><P><I><A><V><L><P><L><A><G><I><F><L><G><I><G><D><A><I><S><S><N><S><S><G><I><V><G><V><K><F><F><G><E><F><I><K><Q><G><G><N><V><V><F><A><N><L><P><I><L><F><A><V><A><I><A><I><T><F><S><Q><D><A><G><V><A><G><F><S><A><F><V><F><W><A...
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.<BOP>
P47315
Q92209
KHSE_CANAL
Homoserine kinase
Candida
<M><S><V><I><S><F><K><I><K><V><P><A><S><S><A><N><I><G><P><G><F><D><V><L><G><I><G><L><Q><L><Y><L><T><I><T><V><T><I><D><P><S><I><D><T><S><S><D><P><H><H><A><L><L><S><Y><E><G><D><G><K><V><P><F><E><S><N><E><N><L><I><T><Q><T><A><L><Y><V><M><R><C><N><G><I><K><D><F><P><R><G><T><H><I><H><V><N><N><P><I><P><L><G><R><G><L><G><S><S...
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.<BOP>
Q92209
P38623
RCK2_YEAST
CAM kinase-like protein kinase CLK1
Saccharomyces
<M><L><K><I><K><A><L><F><S><K><K><K><P><D><Q><A><D><L><S><Q><E><S><K><K><P><F><K><G><K><T><R><S><S><G><T><N><N><K><D><V><S><Q><I><T><S><S><P><K><K><S><F><Q><D><K><N><I><V><Q><Y><P><S><V><V><A><D><D><H><H><M><K><S><L><T><D><E><L><V><T><T><I><D><S><D><S><S><P><S><D><N><I><T><T><E><N><V><E><T><V><T><S><V><P><A><I><D><V><H...
Serine/threonine-protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.<BOP>
P38623
Q5QYN5
IF3_IDILO
Translation initiation factor IF-3
Idiomarina
<M><K><G><G><K><R><T><Q><K><A><A><D><K><N><R><I><N><E><Q><I><T><G><V><D><E><V><R><L><I><G><T><D><G><E><Q><A><G><V><V><S><I><N><E><A><L><D><A><A><A><E><A><G><V><D><L><V><E><M><S><P><N><A><E><P><P><V><C><R><L><M><D><Y><G><K><F><L><F><E><K><S><K><E><Q><K><E><Q><K><K><K><Q><K><Q><I><Q><V><K><E><V><K><F><R><P><G><T><D><E><G...
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.<BOP>
Q5QYN5
P50266
CYB5R_DROVI
Cytochrome b5-related protein
Drosophila
<M><V><I><E><T><W><K><K><S><G><I><A><T><K><F><P><T><Y><R><N><S><A><P><V><T><V><H><S><W><Q><K><G><K><R><Q><D><V><E><A><E><G><L><W><R><I><K><D><G><I><Y><D><F><T><E><F><I><D><K><H><P><G><G><T><F><W><I><R><E><T><K><G><T><D><I><T><E><A><F><E><A><H><H><L><T><T><A><P><E><K><M><I><A><K><Y><K><V><R><D><A><Y><Q><R><I><Y><T><L><T...
May play a role in muscle cell metabolism.<BOP>
P50266
Q8FB81
THIG_ECOL6
Thiazole synthase
Escherichia
<M><L><H><I><A><D><K><T><F><D><S><H><L><F><T><G><T><G><K><F><A><S><S><Q><L><M><V><E><S><I><R><A><S><G><S><Q><L><V><T><L><A><M><K><R><V><D><L><R><Q><H><N><D><A><I><L><E><P><L><I><A><A><G><V><T><L><L><P><N><T><S><G><A><K><T><A><E><E><A><I><F><A><A><H><L><A><R><E><A><L><G><T><N><W><L><K><L><E><I><H><P><D><A><R><W><L><L><P...
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.<BOP>
Q8FB81
Q8L612
MACP1_ARATH
MACPF domain-containing protein At1g14780
Arabidopsis
<M><S><R><D><G><G><D><V><I><E><T><A><V><K><S><L><G><K><G><F><D><L><T><A><D><F><R><L><K><Y><C><K><D><G><D><G><S><A><G><D><D><R><L><V><V><L><D><Q><T><Q><N><R><E><L><H><I><P><G><F><G><V><F><Q><N><V><S><A><D><I><N><C><D><K><G><E><R><T><R><F><R><S><D><I><L><D><F><N><K><M><S><E><Y><F><N><Q><R><S><S><V><T><G><K><I><P><S><G><N...
Negatively controls the salicylic acid (SA)-mediated pathway of programmed cell death in plant immunity.<BOP>
Q8L612
P25576
POF1_YEAST
Promoter of filamentation protein 1
Saccharomyces
<M><K><K><T><F><E><Q><F><R><K><S><N><L><L><F><Q><V><L><K><G><P><Q><H><L><E><C><Q><K><L><F><V><L><D><S><S><F><N><P><P><H><L><A><H><F><Q><L><L><S><Q><T><I><K><N><F><K><L><K><D><T><R><S><H><V><L><L><L><L><A><V><N><N><A><D><K><L><P><K><P><A><S><F><P><T><R><L><E><M><M><C><L><F><A><D><Y><L><Q><E><K><L><P><Q><S><V><V><S><V><G...
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Involved in the salvage pathway for NAD(+) biosynthesis via NMN . Involved in the filamentation pathway. Suppresses the filamentation defect of a KSS1 deletion .<BOP>
P25576
Q18BC9
RNH2_CLOD6
Ribonuclease HII
Clostridioides
<M><Q><D><K><S><V><R><E><I><K><E><I><I><E><T><L><E><V><E><K><Y><M><E><Y><I><E><L><L><R><V><D><E><R><K><S><V><Q><G><L><A><I><K><L><A><K><K><L><D><N><I><R><K><E><E><E><R><L><E><T><I><N><I><F><E><N><E><G><Y><D><K><G><Y><L><Y><I><G><G><I><D><E><A><G><R><G><P><L><A><G><P><V><V><A><S><V><V><V><F><K><K><D><T><K><I><E><G><V><N...
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP>
Q18BC9
Q972C1
GCSPA_SULTO
Glycine dehydrogenase (aminomethyl-transferring) subunit 1
Sulfurisphaera
<M><D><M><H><P><W><L><P><N><I><K><Y><I><E><E><M><L><K><S><I><G><V><N><S><I><D><D><L><F><I><D><V><P><E><E><I><K><L><K><K><E><L><D><L><D><Y><K><K><P><L><S><E><Y><E><I><I><L><K><L><Q><E><L><Q><N><K><N><K><R><L><K><M><P><P><F><L><G><G><G><L><C><P><H><Y><V><P><E><V><V><K><F><I><I><K><R><S><E><F><Y><T><A><Y><T><P><Y><Q><P><E...
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.<BOP>
Q972C1
Q4QLG0
MURD_HAEI8
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Haemophilus
<M><N><A><Y><Q><N><K><N><I><T><I><I><G><L><G><K><T><G><L><S><C><V><D><Y><L><L><S><Q><Q><A><N><I><R><V><I><D><T><R><K><K><P><T><G><I><D><K><L><P><Q><N><I><P><L><H><T><G><S><L><N><Q><E><W><L><L><E><S><D><M><I><V><I><S><P><G><L><A><V><K><T><P><E><I><Q><T><A><L><K><A><G><V><E><V><I><G><D><I><E><L><F><C><R><A><A><T><K><P><I...
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).<BOP>
Q4QLG0
Q3AVC2
ILVC_SYNS9
Ketol-acid reductoisomerase type I
unclassified Synechococcus
<M><A><Q><L><F><Y><D><S><D><A><D><L><G><L><L><N><G><K><T><V><A><I><I><G><Y><G><S><Q><G><H><A><H><A><L><N><L><K><D><S><G><V><N><V><V><V><G><L><Y><E><G><S><R><S><A><E><K><A><K><A><D><G><L><E><V><L><T><V><A><E><A><S><A><K><A><D><W><I><M><V><L><L><P><D><E><F><Q><K><D><V><Y><E><K><E><I><A><P><H><L><K><S><G><K><V><L><S><F><A...
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu...
Q3AVC2
Q3AJS6
HISZ_SYNSC
ATP phosphoribosyltransferase regulatory subunit
unclassified Synechococcus
<M><A><L><Q><P><A><A><G><A><K><D><L><N><P><R><Q><V><E><T><N><R><Q><L><T><E><R><L><A><S><V><Y><R><L><W><G><Y><D><E><V><S><P><P><R><V><E><R><L><A><T><L><M><A><G><G><A><I><D><S><S><D><I><V><R><L><V><A><D><D><P><L><G><L><R><P><E><M><T><A><S><I><A><R><A><A><C><T><R><F><A><D><R><Q><R><P><L><R><L><W><A><S><G><T><V><F><R><T><R...
Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.<BOP>
Q3AJS6
Q9D0C1
RN115_MOUSE
Zinc finger protein 364
Mus
<M><A><E><A><S><A><A><G><A><D><A><G><S><A><V><A><A><H><R><F><F><C><H><F><C><K><G><E><V><N><P><K><L><P><E><Y><I><C><P><R><C><D><S><G><F><I><E><E><V><T><D><D><S><S><F><L><G><G><G><G><S><R><T><D><N><S><T><A><T><H><F><A><E><L><W><D><H><L><D><H><T><M><F><L><Q><D><F><R><P><F><L><S><S><N><P><L><D><Q><D><N><R><A><N><E><R><G><H...
E3 ubiquitin-protein ligase that mediates E2-dependent, 'Lys-48'- and/or 'Lys-63'-linked polyubiquitination of substrates and may play a role in diverse biological processes. Through their polyubiquitination, may play a role in the endosomal trafficking and degradation of membrane receptors including EGFR, FLT3, MET an...
Q9D0C1
Q51520
PHZF_PSECL
Phenazine/pyocyanine biosynthesis protein PhzF
Pseudomonas
<M><H><H><Y><V><I><I><D><A><F><A><S><A><P><L><E><G><N><P><V><T><V><F><F><D><A><D><D><L><S><A><T><Q><M><Q><R><I><A><R><E><M><N><L><S><E><T><T><F><V><L><K><P><R><N><C><G><D><A><L><I><R><I><F><T><P><V><N><E><L><P><F><A><G><H><P><L><L><G><T><A><I><A><L><G><A><H><T><D><N><H><R><L><F><L><E><T><Q><M><G><T><I><A><F><E><L><E><R...
Isomerase that catalyzes the condensation of two molecules of trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) into the phenazine ring system. The final product is not yet known.<BOP>
Q51520
C0MFD9
XERS_STRS7
Tyrosine recombinase XerS
Streptococcus
<M><K><R><D><L><L><L><T><K><I><E><E><Y><K><N><I><M><P><W><Y><V><L><D><Y><Y><Q><S><K><L><S><V><P><Y><S><F><T><T><L><Y><E><Y><L><K><E><Y><K><R><F><F><E><W><L><I><D><S><D><L><S><K><A><A><R><I><A><D><V><D><L><T><T><L><E><H><L><S><K><K><D><M><E><A><F><I><L><Y><L><R><E><R><P><S><L><N><T><Y><S><T><K><K><G><V><S><Q><T><T><I><N...
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.<BOP>
C0MFD9
Q57QP2
CBPA_SALCH
Curved DNA-binding protein
Salmonella
<M><E><L><K><D><Y><Y><A><I><M><G><V><K><P><T><D><D><L><K><T><I><K><T><A><Y><R><R><L><A><R><K><Y><H><P><D><V><S><K><E><P><N><A><E><A><R><F><K><E><V><A><E><A><W><E><V><L><S><D><E><Q><R><R><A><E><Y><D><Q><L><W><Q><H><R><N><D><P><Q><F><N><R><Q><F><Q><Q><H><E><G><Q><P><Y><N><A><E><D><F><D><D><I><F><S><S><I><F><G><Q><H><G><R...
DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lac...
Q57QP2
C5B704
UBIA_EDWI9
4-HB polyprenyltransferase
Edwardsiella
<M><E><G><C><V><A><Q><S><K><W><L><A><Y><C><R><L><M><R><I><D><K><P><I><G><S><L><L><L><L><W><P><T><Y><W><A><L><W><L><A><G><G><T><A><P><G><G><K><L><L><L><V><F><T><C><G><V><F><F><M><R><A><A><G><C><V><I><N><D><F><A><D><R><H><F><D><G><H><V><K><R><T><C><Q><R><P><L><P><C><G><A><L><S><E><R><E><A><K><A><L><F><V><L><L><V><G><L><S...
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-...
C5B704
Q96FG2
ELMD3_HUMAN
RNA-binding protein 29
Homo
<M><N><E><K><S><C><S><F><H><S><K><E><E><L><R><D><G><Q><G><E><R><L><S><A><G><Y><S><P><S><Y><D><K><D><K><S><V><L><A><F><R><G><I><P><I><S><E><L><K><N><H><G><I><L><Q><A><L><T><T><E><A><Y><E><W><E><P><R><V><V><S><T><E><V><V><R><A><Q><E><E><W><E><A><V><D><T><I><Q><P><E><T><G><S><Q><A><S><S><E><Q><P><G><Q><L><I><S><F><S><E><A...
Acts as a GTPase-activating protein (GAP) for ARL2 with low specific activity.<BOP>
Q96FG2
Q9KQH1
NTPPB_VIBCH
7-methyl-GTP pyrophosphatase
Vibrio
<M><Q><N><Y><Q><L><V><L><A><S><T><S><P><F><R><Q><Q><I><L><A><K><L><K><L><P><F><V><T><A><K><P><D><C><D><E><T><P><L><I><G><E><T><P><E><H><L><L><M><R><L><A><E><N><K><A><R><S><C><F><L><A><D><P><S><L><V><I><G><S><D><Q><V><C><V><I><D><D><Q><I><I><G><K><P><L><T><T><E><K><A><V><E><Q><L><L><R><Q><S><G><Q><A><I><T><F><Y><T><G><L...
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.<BOP>
Q9KQH1
Q2J843
METK2_FRACC
Methionine adenosyltransferase 2
Frankia
<M><A><T><R><L><F><T><S><E><S><V><T><E><G><H><P><D><K><I><A><D><Q><I><S><D><S><I><L><D><A><M><I><K><D><D><P><K><S><R><V><A><V><E><T><L><I><T><T><G><Q><V><H><V><A><G><E><V><T><T><K><T><Y><V><D><I><A><S><V><V><R><E><R><I><L><E><I><G><Y><D><S><S><K><K><G><F><D><G><A><S><C><G><V><S><V><S><I><G><A><Q><S><P><D><I><A><Q><G><V...
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.<BOP>
Q2J843
B0BTN9
RISB_ACTPJ
6,7-dimethyl-8-ribityllumazine synthase
Actinobacillus
<M><A><K><I><T><G><N><L><V><A><T><G><L><K><F><G><I><V><T><A><R><F><N><D><F><I><N><D><K><L><L><S><G><A><I><D><T><L><V><R><H><G><A><D><E><N><N><I><D><T><A><W><V><P><G><A><F><E><I><P><L><V><A><K><K><M><A><T><S><G><K><Y><D><A><V><I><C><L><G><T><V><I><R><G><S><T><T><H><Y><D><Y><V><C><N><E><A><A><K><G><I><G><A><V><A><L><E><T...
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<BOP>
B0BTN9
B0REV4
METK_CLAMS
Methionine adenosyltransferase
Clavibacter
<M><T><D><L><R><L><F><T><S><E><S><V><T><E><G><H><P><D><K><I><C><D><Q><I><S><D><S><I><L><D><A><L><L><T><Q><D><P><S><S><R><A><A><V><E><T><L><V><T><T><G><L><V><H><V><A><G><E><V><T><T><S><G><Y><V><D><I><P><Q><I><V><R><D><R><I><R><D><I><G><Y><D><S><S><E><V><G><F><D><G><S><N><C><G><V><T><V><S><I><G><A><Q><S><P><D><I><A><Q><G...
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.<BOP>
B0REV4
Q5LMK7
DAPA_RUEPO
4-hydroxy-tetrahydrodipicolinate synthase
Ruegeria
<M><F><K><G><S><M><P><A><L><V><T><P><F><R><N><G><E><L><D><L><E><A><L><K><R><L><V><E><W><Q><I><G><E><G><S><T><G><L><V><P><V><G><T><T><G><E><S><P><T><L><S><H><E><E><H><E><T><V><V><A><E><V><V><K><A><A><A><G><R><V><P><V><I><A><G><A><G><S><N><N><T><T><E><A><I><R><F><V><Q><F><A><Q><R><I><G><A><D><A><A><L><V><V><T><P><Y><Y><N...
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).<BOP>
Q5LMK7
B5FEA5
PCP_ALIFM
Pyroglutamyl-peptidase I
Aliivibrio
<M><K><K><I><L><I><T><G><F><E><P><F><G><N><D><K><I><N><P><A><L><E><A><V><K><L><I><A><G><R><K><L><N><G><G><E><I><V><I><C><Q><V><P><V><V><R><Y><K><S><I><E><T><V><K><Q><A><I><E><E><Q><Q><P><Y><A><V><I><T><V><G><Q><A><S><G><R><A><A><I><T><P><E><R><I><A><I><N><V><D><D><F><R><I><P><D><N><E><G><I><Q><V><I><D><E><P><V><V><A><G...
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.<BOP>
B5FEA5
A9NNH7
LIAS_PICSI
Lipoic acid synthase
Picea
<M><S><I><N><P><A><F><L><R><R><I><T><W><G><S><K><S><L><H><H><Q><F><T><R><C><Q><V><R><A><L><S><S><S><V><E><Q><T><P><E><S><T><T><P><A><L><S><A><L><R><E><R><L><A><N><G><G><P><T><L><S><D><F><L><T><R><N><L><G><E><E><P><Y><S><V><D><V><G><T><K><K><N><P><L><P><K><P><K><W><M><K><A><A><V><P><G><G><D><K><Y><T><A><I><K><A><K><L><R...
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP>
A9NNH7
A3QEP5
RUVC_SHELP
Holliday junction resolvase RuvC
Shewanella
<M><P><I><I><L><G><V><D><P><G><S><R><I><T><G><Y><G><V><I><Q><C><Q><G><R><Q><Q><I><Y><L><G><S><G><C><I><R><T><Q><S><D><D><L><P><S><R><L><K><V><I><F><D><G><I><S><E><I><I><R><Q><Y><Q><P><D><E><F><A><I><E><R><V><F><L><A><K><N><A><D><S><A><L><K><L><G><Q><A><R><G><A><A><I><V><A><A><T><N><A><Q><L><P><V><A><E><Y><S><A><T><Q><I...
Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.<BOP>
A3QEP5
B8H0A0
FTSI_CAUVN
Penicillin-binding protein 3
Caulobacter
<M><S><L><S><N><L><G><P><G><G><V><H><S><P><L><W><R><W><V><V><E><R><V><W><R><L><E><H><A><F><E><R><S><R><A><A><A><R><P><E><D><D><T><R><I><R><I><F><L><V><M><G><F><F><G><F><C><F><V><G><V><S><L><G><A><G><W><S><A><L><F><S><R><A><G><Q><G><G><G><Y><A><Q><G><V><E><G><A><R><G><D><V><V><D><R><N><G><K><L><L><A><V><D><L><A><H><Y><A...
Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.<BOP>
B8H0A0
A1R6G6
Y2084_PAEAT
Nucleotide-binding protein AAur_2084
Paenarthrobacter
<M><D><E><A><T><A><K><S><G><T><E><Q><D><G><L><T><P><V><K><P><P><E><A><E><L><L><V><V><T><G><M><S><G><A><G><R><S><T><A><S><D><A><L><E><D><H><G><W><Y><V><V><D><N><L><P><P><Q><M><L><G><T><L><A><E><I><V><S><H><A><P><K><S><I><P><K><L><A><V><V><V><D><V><R><S><K><D><L><F><T><D><I><Q><T><A><L><G><A><L><S><A><S><G><I><T><F><R><V...
Displays ATPase and GTPase activities.<BOP>
A1R6G6
Q4KM33
PLEK_RAT
Pleckstrin
Rattus
<M><E><P><K><R><I><R><E><G><Y><L><V><K><K><G><S><V><F><N><T><W><K><P><M><W><V><V><L><L><E><D><G><I><E><F><Y><K><K><K><S><D><N><N><P><K><G><M><I><P><L><K><G><S><T><L><T><S><P><C><Q><D><F><G><K><R><M><F><V><L><K><I><T><T><T><K><Q><Q><D><H><F><F><Q><A><A><Y><L><E><E><R><D><A><W><V><R><D><I><K><K><A><I><K><C><I><E><G><G><Q...
Major protein kinase C substrate of platelets.<BOP>
Q4KM33
Q5ACK7
DRS1_CANAL
ATP-dependent RNA helicase DRS1
Candida
<M><P><D><F><I><L><T><I><D><S><D><E><E><V><D><V><S><D><S><E><Q><L><Q><D><I><N><P><D><F><K><F><Q><I><D><G><E><T><T><N><T><L><E><E><F><D><F><Q><E><N><K><V><K><E><V><D><L><D><E><I><I><K><K><K><G><G><L><K><E><E><S><D><D><E><E><L><A><L><D><G><F><G><M><G><A><S><K><Q><E><E><E><E><E><E><E><E><E><E><V><E><V><P><E><V><K><E><V><V...
ATP-binding RNA helicase involved in ribosome assembly.<BOP>
Q5ACK7
Q8ZTY5
IF2A_PYRAE
eIF-2-alpha
Pyrobaculum
<M><R><L><V><K><K><E><F><P><D><V><G><E><L><V><I><G><T><V><K><K><I><A><E><H><G><A><Y><V><Y><L><D><E><Y><D><L><E><A><F><A><P><T><Q><E><I><V><Q><S><W><F><H><S><I><R><D><Y><V><K><E><G><N><K><T><V><F><K><V><I><S><V><N><P><K><M><R><V><V><E><V><S><L><K><R><V><R><V><D><E><K><E><K><K><L><L><L><Y><R><H><R><V><R><V><L><K><L><L><E...
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.<BOP>
Q8ZTY5
Q9Y0B7
PP4C_DICDI
Serine/threonine-protein phosphatase 4 catalytic subunit
Dictyostelium
<M><S><S><D><L><D><R><Q><I><E><Q><L><K><R><C><E><I><I><K><E><S><E><V><R><A><L><C><S><K><A><R><E><I><L><L><E><E><G><N><V><Q><R><V><D><S><P><V><T><I><C><G><D><I><H><G><Q><F><Y><D><L><K><E><L><F><K><V><G><G><D><C><P><Q><T><N><Y><L><F><M><G><D><F><V><D><R><G><F><Y><S><V><E><T><F><L><L><L><L><A><L><K><V><R><Y><P><D><R><I><T...
Required for development, chemotaxis and the expression of numerous genes.<BOP>
Q9Y0B7
A2XSX6
TIF9_ORYSI
Protein TIFY 9
Oryza sativa
<M><S><T><R><A><P><V><E><L><D><F><L><G><L><R><A><A><A><A><D><A><D><D><R><H><A><K><S><G><G><S><S><A><S><S><S><S><S><I><R><G><M><E><T><S><A><I><A><R><I><G><P><H><L><L><R><R><V><I><A><A><A><R><P><P><P><P><P><S><T><A><P><V><P><E><E><M><P><G><A><A><A><A><A><A><P><M><T><L><F><Y><N><G><S><V><A><V><F><D><V><S><H><D><K><A><E><A...
Repressor of jasmonate responses.<BOP>
A2XSX6
Q5F8N2
DPO4_NEIG1
DNA polymerase IV
Neisseria
<M><S><L><R><K><I><I><H><I><D><M><D><A><F><Y><A><S><V><E><L><R><E><Q><P><H><L><K><G><R><P><V><V><V><A><W><E><G><A><R><S><V><I><C><A><A><S><Y><E><A><R><Q><F><G><L><H><S><A><M><S><V><A><T><V><K><R><L><C><P><Q><A><V><Y><V><P><P><H><F><D><L><Y><R><Q><V><S><A><Q><I><H><A><V><F><R><R><Y><T><D><L><I><E><P><L><S><L><D><E><A><Y...
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in...
Q5F8N2
Q31N85
PLSX_SYNE7
Phosphate-acyl-ACP acyltransferase
Synechococcus
<M><T><R><A><R><I><A><V><D><A><M><G><G><D><F><A><P><E><E><I><V><K><G><A><L><R><A><Q><E><E><L><Q><A><D><V><I><L><V><G><D><P><D><R><L><R><A><I><C><Q><D><H><A><P><H><L><Q><V><R><I><E><A><A><E><E><A><I><A><M><E><D><A><A><V><S><V><R><S><R><P><R><A><S><I><N><V><A><M><D><L><V><K><A><G><E><A><D><A><V><I><S><A><G><H><S><G><A><V...
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.<BOP>
Q31N85
Q0BYA1
RL1_HYPNA
50S ribosomal protein L1
Hyphomonas
<M><A><T><K><G><K><R><A><R><A><I><E><Q><T><V><D><K><T><K><A><Y><S><V><S><E><A><V><K><L><V><K><S><N><A><K><A><K><F><D><E><S><I><E><I><A><I><N><L><G><V><D><P><K><Y><A><D><Q><Q><V><R><S><V><V><N><L><P><A><G><T><G><K><T><I><R><V><A><V><F><A><K><D><K><K><A><E><E><A><L><A><A><G><A><D><I><V><G><A><D><D><L><F><E><K><V><N><G><G...
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.<BOP>
Q0BYA1
O94886
CSCL1_HUMAN
Transmembrane protein 63A
Homo
<M><M><D><S><P><F><L><E><L><W><Q><S><K><A><V><S><I><R><E><Q><L><G><L><G><D><R><P><N><D><S><Y><C><Y><N><S><A><K><N><S><T><V><L><Q><G><V><T><F><G><G><I><P><T><V><L><L><I><D><V><S><C><F><L><F><L><I><L><V><F><S><I><I><R><R><R><F><W><D><Y><G><R><I><A><L><V><S><E><A><D><S><E><S><R><F><Q><R><L><S><S><T><S><S><S><G><Q><Q><D><F...
Acts as an osmosensitive calcium-permeable cation channel . Mechanosensitive ion channel that converts mechanical stimuli into a flow of ion .<BOP>
O94886
B6J1Y7
RNH_COXB2
Ribonuclease H
Coxiella
<M><A><K><Q><E><Q><N><I><V><Y><L><Y><C><D><G><A><C><R><G><N><P><G><P><G><G><W><G><V><L><L><R><Y><N><Q><H><E><R><Q><L><H><G><G><V><A><N><T><T><N><N><Q><M><E><L><T><A><A><I><E><G><L><K><S><L><K><K><P><C><Q><V><V><V><T><T><D><S><Q><Y><L><R><R><G><I><T><E><W><L><P><V><W><K><R><R><G><W><R><T><S><N><K><K><P><V><K><N><Q><P><L...
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP>
B6J1Y7
Q6GBS6
SDRC_STAAS
Serine-aspartate repeat-containing protein C
Staphylococcus
<M><N><N><K><K><T><V><T><N><R><K><G><M><I><P><N><R><L><N><K><F><S><I><R><K><Y><S><V><G><T><A><S><I><L><V><G><T><T><L><I><F><G><L><S><G><H><E><A><K><A><A><E><H><T><N><G><E><L><N><Q><S><K><N><E><T><T><A><P><S><E><N><K><T><T><E><K><V><D><S><R><Q><L><K><D><N><T><Q><T><A><T><A><D><Q><P><K><V><T><M><S><D><S><A><T><V><K><E><T...
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis. Mediates interactions with components of the extracellular matrix such as host NRXN1 to promote bacterial adhesion.<BOP>
Q6GBS6
B6I7J7
ARNC_ECOSE
Undecaprenyl-phosphate Ara4FN transferase
Escherichia
<M><F><E><I><H><P><V><K><K><V><S><V><V><I><P><V><Y><N><E><Q><E><S><L><P><E><L><I><R><R><T><T><T><A><C><E><S><L><G><K><E><Y><E><I><L><L><I><D><D><G><S><S><D><N><S><A><H><M><L><V><E><A><S><Q><A><E><N><S><H><I><V><S><I><L><L><N><R><N><Y><G><Q><H><S><A><I><M><A><G><F><S><H><V><T><G><D><L><I><I><T><L><D><A><D><L><Q><N><P><P...
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.<BOP>
B6I7J7
Q9ZKB1
6PGL_HELPJ
6-phosphogluconolactonase
Helicobacter
<M><G><Y><Q><L><F><E><F><E><N><L><E><D><C><H><K><A><L><I><E><R><F><K><E><F><F><N><A><A><L><K><K><H><H><Q><V><S><V><A><F><S><G><G><R><S><P><I><S><L><L><Q><K><L><S><V><L><D><L><K><W><H><E><C><L><I><S><L><V><D><E><R><I><I><E><A><S><H><E><D><S><N><A><K><L><L><H><D><Y><L><L><Q><N><N><A><L><K><A><S><F><T><P><L><L><P><E><K><I...
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.<BOP>
Q9ZKB1
Q8P243
PCP_STRP8
Pyroglutamyl-peptidase I
Streptococcus
<M><K><I><L><I><T><G><F><D><P><F><G><G><E><A><I><N><P><A><L><E><A><I><K><K><L><P><A><T><I><H><G><A><E><I><K><C><I><E><V><P><T><V><F><Q><K><S><A><D><V><L><Q><Q><H><I><E><S><F><Q><P><D><A><V><L><C><I><G><Q><A><G><G><R><T><G><L><T><P><E><R><V><A><I><N><Q><D><D><A><R><I><P><D><N><E><G><N><Q><P><I><D><T><P><I><R><A><D><G><K...
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.<BOP>
Q8P243
P60209
KAX94_HOTTA
BTK-2
Mesobuthus
<V><G><C><A><E><C><P><M><H><C><K><G><K><M><A><K><P><T><C><E><N><E><V><C><K><C><N><I><G><K><K><D>
Blocker of human voltage-gated potassium channel Kv1.1/KCNA1 .<BOP>
P60209
C6L862
AHLL_MICTS
N-acyl homoserine lactonase
Microbacterium
<M><I><L><A><H><D><V><S><G><S><G><P><L><L><V><L><L><H><G><I><T><E><D><R><R><S><W><D><P><V><D><F><T><D><G><F><T><V><V><R><V><D><L><R><G><H><G><A><S><A><A><E><E><P><Y><D><I><P><T><L><A><T><D><V><H><D><T><L><A><Q><L><A><E><N><D><V><I><P><G><E><L><P><V><I><V><G><H><S><M><G><G><I><V><A><T><A><Y><G><A><L><F><P><A><R><A><I><V...
Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3. Has slight activity towards L-homoserine lactone, and no activity towards gamma-butyrolactone.<BOP>
C6L862
Q6YPI8
ACP_ONYPE
Acyl carrier protein
Candidatus Phytoplasma asteris
<M><V><F><E><K><I><K><A><L><I><A><T><Q><L><S><L><D><A><S><T><I><T><L><D><T><R><F><K><E><D><L><G><L><D><S><L><D><A><L><E><L><V><M><E><V><E><K><T><F><Q><I><N><I><S><D><A><T><L><Q><N><F><K><T><V><Q><D><I><V><F><Y><I><T><K><N><T><P>
Carrier of the growing fatty acid chain in fatty acid biosynthesis.<BOP>
Q6YPI8
Q07532
IWR1_YEAST
Interacting with RNA polymerase II protein 1
Saccharomyces
<M><S><T><I><S><T><T><T><A><P><E><F><I><R><V><K><R><R><R><D><E><D><S><V><Q><A><L><L><I><D><E><G><K><R><V><K><K><Q><K><F><I><F><K><L><S><K><T><V><S><S><E><S><Y><Q><S><E><Q><E><S><S><T><P><L><L><K><L><A><H><E><D><H><R><H><F><V><L><E><Q><R><K><K><S><R><R><D><S><D><D><E><K><S><Q><Q><R><L><A><A><E><G><S><T><V><D><D><D><G><L...
Directs RNA polymerase II nuclear import. Binds RNA polymerase II in the active center cleft between the two largest subunits in the cytoplasm. Then uses an N-terminal bipartite nuclear localization signal that may be recognized by karyopherin alpha to direct the polymerase II complex nuclear import. In the nucleus, is...
Q07532
P56833
MRAY_STRCO
UDP-MurNAc-pentapeptide phosphotransferase
Streptomyces albidoflavus group
<M><K><Q><I><L><F><A><G><V><I><G><L><F><L><T><L><V><G><T><P><L><L><I><K><L><L><A><R><K><G><Y><G><Q><Y><I><R><D><D><G><P><R><E><H><A><S><K><R><G><T><P><T><M><G><G><I><A><F><I><L><A><T><V><A><A><Y><F><L><A><K><G><I><T><S><Y><L><D><P><D><I><D><A><G><P><T><F><S><G><L><L><V><L><G><L><M><V><G><M><G><L><V><G><F><L><D><D><Y><I...
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I...
P56833
A0A0R4I987
CDII_YERPY
Immunity protein CdiI-YPIII
Yersinia
<M><N><D><I><V><K><S><A><W><A><S><V><K><M><N><T><D><F><I><C><V><D><T><Y><S><G><Y><R><S><N><Q><L><D><P><L><G><V><Q><H><L><S><S><P><D><V><S><D><L><D><L><G><E><M><V><K><D><A><L><S><H><S><R><F><V><L><P><A><P><R><T><D><I><W><I><H><P><E><V><T><F><D><L><D><L><Y><D><S><R><R><T><V><E><R><Y><D><E><W><V><K><K><L><M><V><H><Y><G><Y...
Immunity protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion. Neutralizes the toxic activity of c...
A0A0R4I987
O55208
FIGLA_MOUSE
Transcription factor FIGa
Mus
<M><D><T><A><P><A><S><P><E><P><F><L><V><T><P><Q><A><E><V><L><E><E><L><I><Q><A><Q><M><G><P><L><P><R><L><A><A><I><C><R><L><K><R><L><P><S><G><G><Y><S><T><T><D><D><L><H><L><V><L><E><R><R><R><V><A><N><A><K><E><R><E><R><I><K><N><L><N><R><G><F><A><K><L><K><A><L><V><P><F><L><P><Q><S><R><K><P><S><K><V><D><I><L><K><G><A><T><E><Y...
Germ-line specific transcription factor implicated in postnatal oocyte-specific gene expression. Plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and earl...
O55208
Q6AAU3
GLYA_CUTAK
Serine hydroxymethyltransferase
Cutibacterium
<M><S><D><P><R><A><V><D><P><T><A><R><D><I><A><E><K><L><A><P><A><Y><R><T><M><L><D><A><I><A><Q><V><E><P><R><I><A><E><A><T><R><A><E><L><T><D><Q><R><H><S><L><K><L><I><A><S><E><N><Y><A><S><L><P><V><L><A><T><M><G><T><W><F><S><D><K><Y><A><E><G><T><A><G><H><R><F><Y><A><G><C><Q><N><V><D><T><V><E><T><I><A><A><E><H><A><C><A><L><F...
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a...
Q6AAU3
Q0HEW2
MDH_SHESM
Malate dehydrogenase
Shewanella
<M><K><V><A><V><L><G><A><A><G><G><I><G><Q><A><L><A><L><L><L><K><T><Q><L><P><A><G><S><Q><L><S><L><Y><D><I><A><P><V><T><P><G><V><A><V><D><L><S><H><I><P><T><A><V><E><I><K><G><F><A><G><E><D><P><T><P><A><L><V><G><A><D><V><V><L><I><S><A><G><V><A><R><K><P><G><M><D><R><S><D><L><F><N><I><N><A><G><I><V><R><N><L><I><E><K><V><A><V...
Catalyzes the reversible oxidation of malate to oxaloacetate.<BOP>
Q0HEW2
C6DGY3
CLSA_PECCP
Cardiolipin synthase A
Pectobacterium
<M><S><T><F><Y><T><V><I><S><W><L><L><V><F><G><Y><W><L><L><I><A><G><V><T><L><R><I><L><M><K><R><R><A><V><P><S><A><M><A><W><L><L><V><I><Y><I><L><P><L><V><G><I><V><A><Y><L><S><F><G><E><L><H><L><G><K><R><R><A><E><R><A><S><K><M><W><P><S><T><A><K><W><L><R><E><L><K><E><Y><R><R><I><F><A><T><E><N><S><E><V><A><S><A><L><F><Q><L><C...
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.<BOP>
C6DGY3
B2A4D5
RS7_NATTJ
30S ribosomal protein S7
Natranaerobius
<M><S><R><K><G><P><A><P><K><R><D><V><N><P><D><P><I><Y><N><S><K><M><V><T><K><F><I><N><K><L><M><L><D><G><K><K><G><L><S><Q><R><I><F><Y><K><A><L><E><L><V><G><E><R><T><N><E><E><P><L><E><V><F><E><T><A><V><K><N><V><M><P><V><L><E><V><K><A><R><R><V><G><G><A><T><Y><Q><V><P><V><E><V><E><P><N><R><K><Q><V><L><A><I><R><W><I><V><N><Y...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.<BOP>
B2A4D5
A0PJR5
ECHD3_DANRE
Enoyl-CoA hydratase domain-containing protein 3, mitochondrial
Danio
<M><L><L><R><G><F><S><E><L><L><K><C><R><G><V><M><M><K><M><R><M><K><M><S><G><D><S><S><S><L><T><L><T><E><Q><Q><G><G><I><R><R><I><I><L><N><N><P><R><K><R><N><A><L><S><L><Q><M><L><E><S><L><R><E><N><I><L><T><D><A><D><N><P><E><L><H><V><I><I><I><S><A><V><G><P><V><F><S><S><G><H><D><L><Q><E><L><S><S><A><E><G><S><D><L><P><R><R><V...
May play a role in fatty acid biosynthesis and insulin sensitivity.<BOP>
A0PJR5
A7N2Q0
BETB_VIBC1
Betaine aldehyde dehydrogenase
Vibrio
<M><D><M><K><A><H><Y><I><D><G><A><M><H><L><G><C><S><E><E><H><F><T><T><Y><N><P><A><N><G><E><P><L><A><N><V><K><Q><A><N><Q><Q><D><M><Q><A><A><I><E><S><A><K><R><G><F><A><I><W><S><A><M><T><A><T><E><R><S><R><I><L><L><K><A><V><A><L><L><R><E><R><N><D><E><L><A><A><L><E><V><A><D><T><G><K><P><I><Q><E><A><N><C><V><D><I><A><T><G><A...
Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.<BOP>
A7N2Q0
P08228
SODC_MOUSE
Superoxide dismutase [Cu-Zn]
Mus
<M><A><M><K><A><V><C><V><L><K><G><D><G><P><V><Q><G><T><I><H><F><E><Q><K><A><S><G><E><P><V><V><L><S><G><Q><I><T><G><L><T><E><G><Q><H><G><F><H><V><H><Q><Y><G><D><N><T><Q><G><C><T><S><A><G><P><H><F><N><P><H><S><K><K><H><G><G><P><A><D><E><E><R><H><V><G><D><L><G><N><V><T><A><G><K><D><G><V><A><N><V><S><I><E><D><R><V><I><S><L...
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.<BOP>
P08228
P33711
SOMA_CANLF
Growth hormone
Canis
<M><A><A><S><P><R><N><S><V><L><L><A><F><A><L><L><C><L><P><W><P><Q><E><V><G><A><F><P><A><M><P><L><S><S><L><F><A><N><A><V><L><R><A><Q><H><L><H><Q><L><A><A><D><T><Y><K><E><F><E><R><A><Y><I><P><E><G><Q><R><Y><S><I><Q><N><A><Q><A><A><F><C><F><S><E><T><I><P><A><P><T><G><K><D><E><A><Q><Q><R><S><D><V><E><L><L><R><F><S><L><L><L...
Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.<BOP>
P33711
B5YKP5
MTIP_THEYD
5'-methylthioinosine phosphorylase
Thermodesulfovibrio
<M><H><N><K><Q><Q><V><K><I><G><I><I><G><G><S><G><L><S><E><S><E><A><K><K><E><I><I><T><I><K><T><P><Y><G><E><P><S><C><P><Y><E><I><E><K><I><D><D><I><E><V><L><F><L><R><R><H><G><Q><K><H><S><I><P><P><H><K><V><N><Y><R><A><N><I><Y><G><F><K><N><F><G><I><E><R><I><F><G><V><F><A><T><G><S><L><T><E><N><I><P><P><G><S><I><V><I><P><N><Q...
Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.<...
B5YKP5
A5WGS6
TGT_PSYWF
tRNA-guanine transglycosylase
Psychrobacter
<M><Q><F><T><L><H><K><T><A><A><G><E><S><R><A><R><R><G><T><V><T><V><N><H><G><E><I><R><T><P><A><F><M><P><V><G><T><Y><G><T><V><K><G><M><L><P><R><D><I><E><D><I><G><A><D><I><I><L><G><N><T><F><H><L><W><L><R><P><G><T><E><V><I><D><K><F><G><G><L><H><Q><F><M><N><W><N><K><P><I><L><T><D><S><G><G><F><Q><V><F><S><L><G><A><M><R><K><I...
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th...
A5WGS6
O78516
FTSH_GUITH
ATP-dependent zinc metalloprotease FtsH
Guillardia
<M><K><I><S><W><K><N><I><L><L><T><L><I><P><L><G><L><I><S><F><L><V><W><Q><G><F><N><N><T><T><N><P><Q><F><T><K><N><I><A><S><S><R><M><T><Y><G><R><F><L><E><Y><L><D><L><G><W><V><K><K><V><D><L><Y><D><E><G><H><T><A><I><V><E><A><I><G><P><E><L><G><N><R><I><Q><R><I><R><V><E><L><P><A><T><A><P><E><L><I><T><K><L><R><K><A><N><V><D><L...
Acts as a processive, ATP-dependent zinc metallopeptidase.<BOP>
O78516
O62327
GPX2_CAEEL
Glutathione peroxidase 2
Caenorhabditis
<M><A><S><V><H><G><I><T><V><K><N><A><Q><G><E><D><T><P><L><S><N><Y><Q><G><K><V><L><I><I><V><N><V><A><S><Q><C><G><L><T><N><S><N><Y><N><Q><F><K><E><L><L><D><V><Y><K><K><D><G><L><E><V><L><A><F><P><C><N><Q><F><G><G><Q><E><P><S><C><E><I><D><I><A><A><F><V><A><D><K><F><K><F><E><P><T><L><F><Q><K><I><D><V><N><G><D><N><T><A><P><L...
May constitute a glutathione peroxidase-like protective system against oxidative stresses.<BOP>
O62327
Q6S5L9
SHC4_MOUSE
Src homology 2 domain-containing-transforming protein C4
Mus
<M><R><E><R><S><Q><D><S><Q><A><G><L><T><L><Y><V><G><L><F><G><H><L><G><M><L><H><R><T><K><Y><S><R><F><R><N><E><S><I><T><S><L><D><E><G><S><P><G><G><S><V><G><N><K><G><S><S><P><P><P><Y><P><A><L><A><P><H><L><P><T><E><D><A><T><V><S><S><Q><E><S><P><T><A><L><C><T><L><I><P><R><M><A><S><M><K><L><A><N><P><I><T><F><L><G><L><K><T><F...
Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.<BOP>
Q6S5L9
B0SA31
RL18_LEPBA
50S ribosomal protein L18
Leptospira
<M><I><N><K><T><A><K><N><T><K><R><L><R><R><A><E><R><V><R><Y><K><L><R><Q><T><S><E><R><P><R><L><V><F><N><K><T><N><R><Y><L><T><A><Q><I><I><D><D><A><K><G><V><T><L><V><Y><A><T><T><L><E><K><D><F><P><K><H><E><N><S><K><K><S><K><S><A><A><T><E><L><G><K><V><V><A><D><K><A><K><K><A><G><V><S><Q><V><V><L><D><R><S><G><M><V><Y><H><G><R...
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP>
B0SA31
Q9UJ71
CLC4K_HUMAN
Langerin
Homo
<M><T><V><E><K><E><A><P><D><A><H><F><T><V><D><K><Q><N><I><S><L><W><P><R><E><P><P><P><K><S><G><P><S><L><V><P><G><K><T><P><T><V><R><A><A><L><I><C><L><T><L><V><L><V><A><S><V><L><L><Q><A><V><L><Y><P><R><F><M><G><T><I><S><D><V><K><T><N><V><Q><L><L><K><G><R><V><D><N><I><S><T><L><D><S><E><I><K><K><N><S><D><G><M><E><A><A><G><V...
Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in t...
Q9UJ71
Q9W5B6
MTU1_DROME
Mitochondrial tRNA-specific 2-thiouridylase 1
Sophophora
<M><I><R><N><V><V><V><G><V><S><G><G><V><D><S><A><V><S><A><H><L><L><A><E><Q><G><F><K><V><L><G><V><F><M><R><N><W><D><E><A><D><E><V><G><R><C><S><G><E><A><D><L><K><D><A><E><W><A><C><R><Q><L><G><V><E><L><R><Q><V><N><Y><V><R><E><Y><W><T><A><V><F><S><Q><F><L><D><D><Y><Q><M><G><L><T><P><N><P><D><I><L><C><N><R><H><I><K><F><D><L...
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble ...
Q9W5B6
A5IN99
PANC_THEP1
Pantoate-activating enzyme
Thermotoga
<M><K><I><I><E><T><I><E><E><M><K><K><F><S><E><E><M><R><E><K><K><K><T><I><G><F><V><P><T><M><G><Y><L><H><E><G><H><L><S><L><V><R><R><A><R><D><E><N><D><V><V><V><V><S><I><F><V><N><P><T><Q><F><G><P><N><E><D><Y><E><R><Y><P><R><D><F><E><R><D><R><K><L><L><E><K><E><N><V><D><C><I><F><H><P><S><V><E><E><M><Y><P><P><D><F><S><T><Y><V...
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<BOP>
A5IN99
Q10133
RHO2_SCHPO
GTP-binding protein rho2
Schizosaccharomyces
<M><L><Q><S><Q><P><I><R><R><K><L><V><V><V><G><D><G><A><C><G><K><T><S><L><L><S><V><F><T><L><G><Y><F><P><T><E><Y><V><P><T><V><F><E><N><Y><V><S><D><C><R><V><D><G><K><S><V><Q><L><A><L><W><D><T><A><G><Q><E><E><Y><E><R><L><R><P><M><S><Y><A><K><A><H><I><I><L><V><G><F><A><I><D><S><P><D><S><L><E><N><V><S><T><K><W><I><E><E><I><N...
Involved in cell morphogenesis, the maintenance of growth direction, control of polarity and of cell wall integrity. Regulates the synthesis of alpha-D-glucan through activation of pck2.<BOP>
Q10133
Q8R6T8
PURA_CALS4
IMP--aspartate ligase
Caldanaerobacter
<M><S><V><T><V><I><V><G><A><Q><W><G><D><E><G><K><G><K><I><T><D><Y><L><A><E><R><S><E><V><V><V><R><Y><Q><G><G><N><N><A><G><H><T><V><E><K><D><G><V><Q><Y><K><L><H><L><I><P><S><G><I><L><Y><P><D><K><I><C><V><I><G><N><G><V><V><V><D><P><S><A><L><L><K><E><I><E><D><L><K><A><K><G><V><E><V><K><E><D><N><L><K><I><S><D><R><A><H><V><V...
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP>
Q8R6T8
Q67PR8
RPOZ_SYMTH
Transcriptase subunit omega
Symbiobacterium
<M><I><K><P><S><L><D><Q><L><M><H><L><V><D><S><K><Y><T><L><V><I><L><A><A><R><R><A><R><D><L><Q><D><G><K><H><Q><M><V><E><S><K><S><N><K><P><V><T><I><A><L><E><E><L><A><A><G><K><L><F><F><E><R><G><K><P><T><P><L><G>
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP>
Q67PR8
P02163
MYG_ROUAE
Myoglobin
Rousettus
<M><G><L><S><D><G><E><W><Q><L><V><L><N><V><W><G><K><V><E><A><D><I><P><G><H><G><Q><E><V><L><I><R><L><F><K><G><H><P><E><T><L><E><K><F><D><K><F><K><H><L><K><S><E><D><E><M><K><A><S><E><D><L><K><K><H><G><A><T><V><L><T><A><L><G><G><I><L><K><K><K><G><Q><H><E><A><Q><L><K><P><L><A><Q><S><H><A><T><K><H><K><I><P><V><K><Y><L><E><F...
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.<BOP>
P02163
Q6LU31
GUAA_PHOPR
Glutamine amidotransferase
Photobacterium
<M><T><T><S><T><N><I><H><D><Q><R><I><L><I><L><D><F><G><S><Q><Y><T><Q><L><I><A><R><R><I><R><E><I><G><V><Y><C><E><L><W><S><W><D><V><D><E><A><D><I><R><D><F><N><P><N><G><I><I><L><S><G><G><P><E><S><V><T><G><D><E><S><P><R><A><P><Q><Y><V><F><E><A><G><V><P><V><F><G><V><C><Y><G><M><Q><T><M><A><E><Q><L><G><G><K><V><A><G><S><S><M...
Catalyzes the synthesis of GMP from XMP.<BOP>
Q6LU31
Q88PD5
SODF_PSEPK
Superoxide dismutase [Fe]
Pseudomonas
<M><A><F><E><L><P><P><L><P><Y><A><H><D><A><L><Q><P><H><I><S><K><E><T><L><E><Y><H><H><D><K><H><H><N><T><Y><V><V><N><L><N><N><L><V><P><G><T><E><F><E><G><K><T><L><E><E><I><V><K><S><S><S><G><G><I><F><N><N><A><A><Q><V><W><N><H><T><F><Y><W><N><C><L><S><P><N><G><G><G><Q><P><T><G><A><L><A><D><A><I><N><A><A><F><G><S><F><D><K><F...
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.<BOP>
Q88PD5
P42111
YXAL_BACSU
Uncharacterized protein YxaL
Bacillus
<M><V><K><S><F><R><M><K><A><L><I><A><G><A><A><V><A><A><A><V><S><A><G><A><V><S><D><V><P><A><A><K><V><L><Q><P><T><A><A><Y><A><A><E><T><V><F><S><Q><N><N><G><A><S><G><F><L><P><G><R><Y><D><V><Q><A><M><A><P><A><M><F><N><W><S><R><E><S><R><F><A><G><N><T><D><G><T><L><K><W><Q><N><D><I><R><T><T><P><Q><N><G><A><G><A><V><I><D><G><D...
Increases the processivity of the PcrA helicase, but does not bind to DNA.<BOP>
P42111
A4W7Z0
MTNK_ENT38
Methylthioribose kinase
Enterobacter
<M><S><Q><Y><R><T><F><T><A><Q><D><A><V><E><Y><A><K><Q><F><G><G><L><D><N><P><S><S><L><V><E><A><Q><E><I><G><D><G><N><L><N><L><V><F><K><I><F><D><A><Q><G><V><S><R><I><I><V><K><Q><A><L><P><Y><V><R><C><V><G><E><S><W><P><L><T><L><D><R><A><R><L><E><A><Q><T><L><V><E><H><Y><Q><H><S><P><Q><H><T><V><K><I><H><H><Y><D><P><E><L><A><V...
Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate.<BOP>
A4W7Z0
Q8U1R2
PANB_PYRFU
Ketopantoate hydroxymethyltransferase
Pyrococcus
<M><R><E><I><T><P><K><R><I><M><E><M><K><G><K><E><K><I><T><M><I><T><A><Y><D><Y><P><S><A><L><L><A><D><K><A><G><F><D><I><V><F><V><G><D><S><L><G><M><V><V><Y><G><E><Q><N><T><L><N><V><T><M><D><Q><M><I><F><H><T><R><A><V><A><K><A><V><K><R><A><L><V><L><A><D><M><P><F><G><S><Y><E><V><S><V><E><E><G><V><K><N><A><I><K><L><I><Q><A><G...
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.<BOP>
Q8U1R2
Q5L3Z4
RL2_GEOKA
50S ribosomal protein L2
Geobacillus thermoleovorans group
<M><A><I><K><K><Y><K><P><T><S><N><G><R><R><G><M><T><V><L><D><F><S><E><I><T><T><D><Q><P><E><K><S><L><L><A><P><L><K><K><K><A><G><R><N><N><Q><G><K><I><T><V><R><H><Q><G><G><G><H><K><R><Q><Y><R><I><I><D><F><K><R><D><K><D><G><I><P><G><R><V><A><T><I><E><Y><D><P><N><R><S><A><N><I><A><L><I><N><Y><A><D><G><E><K><R><Y><I><I><A><P...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
Q5L3Z4
Q5YXQ1
MAIA_NOCFA
Maleate cis-trans isomerase
Nocardia
<M><G><I><R><R><I><G><L><V><V><P><S><S><N><V><T><V><E><T><E><M><P><A><L><L><S><R><H><P><G><A><E><F><S><F><H><S><T><R><M><R><M><H><T><V><S><P><E><G><L><A><A><M><N><A><Q><R><E><R><C><V><L><E><I><A><D><A><A><P><E><V><I><L><Y><A><C><L><V><A><V><M><V><G><G><P><G><E><H><H><R><V><E><S><A><V><A><E><Q><L><A><T><G><G><S><Q><A><L...
Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate. Shows a strict specificity for maleate, with no activity detected toward structurally related substrates including citraconate, mesaconate, dimethylmaleate, and maleamide.<BOP>
Q5YXQ1
Q9C8H0
AB12C_ARATH
Multidrug resistance-associated protein 13
Arabidopsis
<M><G><F><E><A><L><N><W><Y><C><K><P><V><A><D><G><F><W><E><K><A><V><D><G><A><F><G><A><Y><T><P><C><A><I><D><S><L><V><M><L><V><S><H><F><V><L><L><G><L><C><F><Y><R><I><W><I><I><F><H><N><T><K><A><Q><I><Y><V><L><R><K><K><Y><Y><N><C><V><L><G><L><L><A><C><Y><C><V><V><E><P><V><L><R><L><V><M><G><I><S><L><F><D><M><D><E><E><T><D><F...
Pump for glutathione S-conjugates.<BOP>
Q9C8H0
B0KDB8
ADDB_THEP3
ATP-dependent helicase/nuclease AddB
Thermoanaerobacter
<M><G><I><R><F><I><Y><G><R><A><G><T><G><K><T><Y><F><C><L><R><E><I><K><E><K><I><N><D><G><N><S><H><P><L><I><L><L><V><P><E><Q><F><T><F><E><A><E><K><Y><L><L><E><T><V><E><K><D><R><K><M><R><A><Q><V><L><S><F><K><T><L><A><N><R><V><F><T><E><V><G><G><L><T><R><Q><H><V><N><S><C><G><R><S><M><V><I><Y><K><I><M><E><D><L><K><E><N><L><K...
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5...
B0KDB8
Q26972
SEM1A_TRICF
Semaphorin-I
Tribolium
<M><V><V><K><I><L><V><W><S><I><C><L><I><A><L><C><H><A><W><M><P><D><S><S><S><K><L><I><N><H><F><K><S><V><E><S><K><S><F><T><G><N><A><T><F><P><D><H><F><I><V><L><N><Q><D><E><T><S><I><L><V><G><G><R><N><R><V><Y><N><L><S><I><F><D><L><S><E><R><K><G><G><R><I><D><W><P><S><S><D><A><H><G><Q><L><C><I><L><K><G><K><T><D><D><D><C><Q><N...
Plays a role in growth cones guidance.<BOP>
Q26972
P39683
NPT1_YEAST
Nicotinate phosphoribosyltransferase
Saccharomyces
<M><S><E><P><V><I><K><S><L><L><D><T><D><M><Y><K><I><T><M><H><A><A><V><F><T><N><F><P><D><V><T><V><T><Y><K><Y><T><N><R><S><S><Q><L><T><F><N><K><E><A><I><N><W><L><K><E><Q><F><S><Y><L><G><N><L><R><F><T><E><E><E><I><E><Y><L><K><Q><E><I><P><Y><L><P><S><A><Y><I><K><Y><I><S><S><S><N><Y><K><L><H><P><E><E><Q><I><S><F><T><S><E><E...
Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate . Essential for growth under anaerobic conditions .<BOP>
P39683
P0AD98
LIVJ_ECO57
Leu/Ile/Val-binding protein
Escherichia
<M><N><I><K><G><K><A><L><L><A><G><C><I><A><L><A><F><S><N><M><A><L><A><E><D><I><K><V><A><V><V><G><A><M><S><G><P><V><A><Q><Y><G><D><Q><E><F><T><G><A><E><Q><A><V><A><D><I><N><A><K><G><G><I><K><G><N><K><L><Q><I><V><K><Y><D><D><A><C><D><P><K><Q><A><V><A><V><A><N><K><V><V><N><D><G><I><K><Y><V><I><G><H><L><C><S><S><S><T><Q><P...
This protein is a component of the leucine, isoleucine, valine, (threonine) transport system, which is one of the two periplasmic binding protein-dependent transport systems of the high-affinity transport of the branched-chain amino acids.<BOP>
P0AD98
Q8L765
BPM1_ARATH
Protein BTB-POZ AND MATH DOMAIN 1
Arabidopsis
<M><G><T><T><R><V><C><S><E><V><S><S><G><S><S><K><S><L><S><Q><S><L><T><V><S><T><S><T><T><E><T><V><N><G><F><H><E><F><K><I><C><G><Y><S><L><A><K><G><V><G><V><G><K><Y><V><A><S><D><T><F><M><V><G><G><Y><S><W><A><I><Y><F><Y><P><D><G><K><S><P><E><D><N><S><S><Y><V><S><L><F><I><A><L><A><S><E><G><A><D><V><R><A><L><F><E><L><T><L><V...
May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.<BOP>
Q8L765
Q145X4
PTH_PARXL
Peptidyl-tRNA hydrolase
Paraburkholderia
<M><I><K><L><I><V><G><L><G><N><P><G><A><E><Y><T><A><T><R><H><N><A><G><F><W><L><V><D><Q><L><A><R><E><A><G><T><T><L><R><D><E><R><R><F><H><G><F><Y><A><K><A><R><L><H><G><E><E><V><H><L><L><E><P><Q><T><Y><M><N><R><S><G><Q><S><V><V><A><L><A><Q><F><F><K><I><L><P><D><E><I><L><V><A><H><D><E><L><D><M><P><P><G><S><V><K><L><K><L><G...
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.<BOP>
Q145X4
A0A023GPI8
LECA_CANBL
Lectin gamma chain
Canavalia
<A><D><T><I><V><A><V><E><L><D><T><Y><P><N><T><D><I><G><D><P><S><Y><P><H><I><G><I><D><I><K><S><V><R><S><K><K><T><A><K><W><N><M><Q><N><G><K><V><G><T><A><H><I><I><Y><N><S><V><G><K><R><L><S><A><V><V><S><Y><P><N><G><D><S><A><T><V><S><Y><D><V><D><L><D><N><V><L><P><E><W><V><R><V><G><L><S><A><T><T><G><L><Y><K><E><T><N><T><I><L...
D-mannose/D-glucose-binding lectin . Has anti-inflammatory activity in animal models when applied intravenously . Has antinociceptive activity in mice when applied intravenously .<BOP>
A0A023GPI8
A6X0C8
RL14_BRUA4
50S ribosomal protein L14
Brucella
<M><I><Q><M><Q><T><N><L><D><V><A><D><N><S><G><A><R><R><V><M><C><I><K><V><L><G><G><S><K><R><R><Y><A><S><V><G><D><I><I><V><V><S><I><K><E><A><I><P><R><G><R><V><K><K><G><D><V><M><K><A><V><V><V><R><T><A><K><D><I><R><R><P><D><G><S><V><I><R><F><D><N><N><A><A><V><L><I><D><N><K><K><E><P><I><G><T><R><I><F><G><P><V><P><R><E><L><R...
Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.<BOP>
A6X0C8
Q5SK67
PYRC_THET8
Dihydroorotase
Thermus
<M><I><L><I><R><N><V><R><L><V><D><A><R><G><E><R><G><P><A><D><V><L><I><G><E><G><R><I><L><S><L><E><G><G><E><A><K><Q><V><V><D><G><T><G><C><F><L><A><P><G><F><L><D><L><H><A><H><L><R><E><P><G><E><E><V><K><E><D><L><F><S><G><L><L><A><A><V><R><G><G><Y><T><D><L><V><S><M><P><N><T><K><P><P><V><D><T><P><E><A><V><R><A><L><K><E><K><A...
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.<BOP>
Q5SK67
Q4UWC9
ACCD_XANC8
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Xanthomonas
<M><S><W><L><S><K><L><M><P><S><G><I><R><T><E><N><T><P><A><K><K><R><S><V><P><E><G><L><W><E><K><C><S><N><C><G><S><A><L><Y><G><P><E><L><E><E><N><L><E><V><C><P><K><C><D><H><H><M><A><I><R><A><R><A><R><L><A><A><L><F><D><L><D><S><P><T><T><E><I><A><A><Q><L><G><P><V><D><V><L><K><F><K><D><Q><K><K><Y><G><E><R><I><K><A><S><Q><K><S...
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.<BOP>
Q4UWC9
Q8W032
CDC6B_ARATH
Cell division control protein 6 homolog B
Arabidopsis
<M><P><T><N><A><G><T><S><L><S><S><Y><K><H><I><V><A><I><G><T><T><V><K><S><E><S><L><E><S><A><A><Y><E><I><P><R><K><R><K><M><R><S><D><S><A><A><V><S><G><N><S><V><S><T><P><K><K><L><K><S><H><L><P><S><S><V><P><N><P><G><M><S><E><K><E><V><V><E><D><S><N><E><I><L><R><Y><P><V><N><L><A><V><S><D><C><L><G><T><K><S><K><W><S><P><R><D><E...
May be involved in the initiation of DNA replication.<BOP>
Q8W032
Q47PU3
PAMO_THEFY
Baeyer-Villiger monooxygenase
Thermobifida
<M><A><G><Q><T><T><V><D><S><R><R><Q><P><P><E><E><V><D><V><L><V><V><G><A><G><F><S><G><L><Y><A><L><Y><R><L><R><E><L><G><R><S><V><H><V><I><E><T><A><G><D><V><G><G><V><W><Y><W><N><R><Y><P><G><A><R><C><D><I><E><S><I><E><Y><C><Y><S><F><S><E><E><V><L><Q><E><W><N><W><T><E><R><Y><A><S><Q><P><E><I><L><R><Y><I><N><F><V><A><D><K><F...
Catalyzes a Baeyer-Villiger oxidation reaction, i.e. the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl acetate. Can also oxidize other aromatic ketones (benzylacetone, ...
Q47PU3
P67086
MIAB_MYCBO
tRNA-i(6)A37 methylthiotransferase
Mycobacterium tuberculosis complex
<M><V><A><H><D><A><A><A><G><V><T><G><E><G><A><G><P><P><V><R><R><A><P><A><R><T><Y><Q><V><R><T><Y><G><C><Q><M><N><V><H><D><S><E><R><L><A><G><L><L><E><A><A><G><Y><R><R><A><T><D><G><S><E><A><D><V><V><V><F><N><T><C><A><V><R><E><N><A><D><N><R><L><Y><G><N><L><S><H><L><A><P><R><K><R><A><N><P><D><M><Q><I><A><V><G><G><C><L><A><Q...
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.<BOP>
P67086
B2TZN1
HPCH_SHIB3
4-hydroxy-2-ketoheptane-1,7-dioate aldolase
Shigella
<M><E><N><S><F><K><A><A><L><K><A><G><R><P><Q><I><G><L><W><L><G><L><S><S><S><Y><S><A><E><L><L><A><G><A><G><F><D><W><L><L><I><D><G><E><H><A><P><N><N><V><Q><T><V><L><T><Q><L><Q><A><I><A><P><Y><P><N><Q><P><V><V><R><P><S><W><N><D><P><V><Q><I><K><Q><L><L><D><V><G><T><Q><T><L><L><V><P><M><V><Q><N><A><D><E><A><R><E><A><V><R><A...
Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.<BOP>
B2TZN1
A1JNX2
FOLD_YERE8
Methenyltetrahydrofolate cyclohydrolase
Yersinia
<M><S><A><K><I><I><D><G><K><T><I><A><Q><Q><V><R><N><E><V><A><A><L><V><Q><K><R><L><A><A><G><K><R><A><P><G><L><A><V><V><L><V><G><E><N><P><A><S><Q><I><Y><V><A><S><K><R><K><A><C><E><E><V><G><F><V><S><R><S><Y><D><L><P><M><T><T><T><E><A><E><L><L><A><L><I><D><S><L><N><N><D><S><E><I><D><G><I><L><V><Q><L><P><L><P><A><G><I><D><N...
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP>
A1JNX2
Q1QAQ4
MURB_PSYCK
UDP-N-acetylmuramate dehydrogenase
Psychrobacter
<M><T><S><A><L><C><S><K><P><I><A><P><H><T><L><S><D><D><L><A><D><L><S><Y><S><N><T><M><A><L><A><C><M><A><D><S><V><V><T><L><T><D><E><V><Q><L><D><E><F><M><A><Y><Y><E><Q><D><T><Q><H><R><K><P><L><F><V><L><S><G><G><S><N><V><L><L><P><A><K><L><N><A><I><V><L><R><P><Q><M><R><G><I><Q><V><T><A><Q><T><D><F><H><V><D><I><E><V><M><A><G...
Cell wall formation.<BOP>
Q1QAQ4
Q9URS0
ACTG_PENCH
Actin, gamma
Penicillium chrysogenum species complex
<M><E><E><E><V><A><A><L><V><I><D><N><G><S><G><M><C><K><A><G><F><A><G><D><D><A><P><R><A><V><F><P><S><I><V><G><R><P><R><H><H><G><I><M><I><G><M><G><Q><K><D><S><Y><V><G><D><E><A><Q><S><K><R><G><I><L><T><L><R><Y><P><I><E><H><G><V><V><T><N><W><D><D><M><E><K><I><W><H><H><T><F><Y><N><E><L><R><V><A><P><E><E><H><P><I><L><L><T><E...
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.<BOP>
Q9URS0