accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
P17124
HRH2_CANLF
Gastric receptor I
Canis
<M><I><S><N><G><T><G><S><S><F><C><L><D><S><P><P><C><R><I><T><V><S><V><V><L><T><V><L><I><L><I><T><I><A><G><N><V><V><V><C><L><A><V><G><L><N><R><R><L><R><S><L><T><N><C><F><I><V><S><L><A><I><T><D><L><L><L><G><L><L><V><L><P><F><S><A><F><Y><Q><L><S><C><R><W><S><F><G><K><V><F><C><N><I><Y><T><S><L><D><V><M><L><C><T><A><S><I><L...
The H2 subclass of histamine receptors mediates gastric acid secretion. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.<BOP>
P17124
A7GS78
NAGB_BACCN
Glucosamine-6-phosphate isomerase
Bacillus cereus group
<M><N><I><L><V><V><E><S><Q><E><K><L><A><E><A><G><Y><K><L><I><E><N><V><V><K><S><K><G><N><P><T><L><G><M><A><T><G><S><S><P><L><G><I><Y><A><E><I><R><K><N><K><L><D><T><S><H><V><T><T><V><N><L><D><E><Y><V><N><L><P><H><E><D><K><N><S><Y><H><Y><F><M><K><E><Q><L><F><D><H><L><P><F><K><A><T><Y><V><P><N><G><M><A><N><D><L><E><E><E><C...
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.<BOP>
A7GS78
P29193
CAPP1_SACHY
Phosphoenolpyruvate carboxylase, housekeeping isozyme
unclassified Saccharum
<M><A><R><N><A><V><D><K><A><T><S><I><D><A><Q><L><R><L><L><A><P><Q><K><L><S><D><D><D><K><L><V><E><Y><D><A><L><L><L><D><R><F><L><D><I><L><Q><D><L><H><G><E><D><I><R><E><T><V><Q><E><C><Y><E><L><A><A><E><Y><E><N><K><L><D><P><K><M><L><D><E><I><G><N><V><L><T><S><L><D><P><G><D><S><I><V><I><T><K><S><F><S><H><M><L><I><L><A><N><L...
Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.<BOP>
P29193
Q2KDA1
RNPH_RHIEC
tRNA nucleotidyltransferase
Rhizobium
<M><R><P><S><G><R><K><T><D><Q><M><R><K><V><S><F><E><R><N><F><S><K><H><A><E><G><S><C><L><V><K><F><G><D><T><H><V><L><C><T><A><S><L><E><E><K><T><P><P><W><L><R><N><T><G><K><G><W><V><T><A><E><Y><G><M><L><P><R><A><T><G><E><R><M><K><R><E><A><A><A><G><K><Q><G><G><R><T><Q><E><I><Q><R><L><I><G><R><S><L><R><A><V><V><D><L><Q><A><L...
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably p...
Q2KDA1
B2TLY9
RS20_CLOBB
30S ribosomal protein S20
Clostridium
<M><A><N><I><K><S><A><K><K><R><I><K><V><T><E><T><K><T><L><N><N><R><M><I><K><S><A><L><K><T><V><I><K><K><F><E><A><A><V><A><G><N><N><V><E><E><A><K><T><V><F><V><A><V><T><K><S><L><D><V><A><A><S><K><G><V><V><H><K><N><M><A><A><R><K><K><S><R><L><A><A><K><L><N><A><M><A>
Binds directly to 16S ribosomal RNA.<BOP>
B2TLY9
Q28TR2
FOLD_JANSC
Methenyltetrahydrofolate cyclohydrolase
unclassified Jannaschia
<M><T><E><P><Q><T><N><R><T><S><G><A><K><I><I><D><G><K><A><F><A><A><D><V><R><G><Q><V><A><G><H><V><Q><R><L><K><D><E><H><G><I><T><P><G><L><A><V><V><L><V><G><E><D><P><A><S><E><V><Y><V><S><H><K><H><K><A><T><V><E><V><G><M><T><S><F><E><H><K><L><P><A><D><T><S><E><D><D><L><F><A><L><I><D><K><L><N><A><D><P><A><V><H><G><I><L><C><Q...
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP>
Q28TR2
A9W1Z5
URED1_METEP
Urease accessory protein UreD 1
Methylorubrum
<M><A><L><S><L><D><G><L><P><E><K><P><A><P><A><E><A><P><S><P><P><V><G><R><R><V><Q><A><S><L><V><F><A><R><G><G><R><T><T><V><L><S><R><Q><V><V><P><Y><P><F><H><I><T><R><A><F><R><M><H><P><E><S><P><D><L><A><T><L><Y><L><Q><S><A><S><G><G><L><Y><A><A><D><H><L><T><L><A><I><A><A><R><A><G><A><R><A><H><V><T><T><Q><A><G><T><V><V><H><R...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
A9W1Z5
Q8CMQ2
AHPC_STAES
Thioredoxin peroxidase
Staphylococcus
<M><S><L><I><N><K><E><I><L><P><F><T><A><Q><A><Y><D><P><K><K><D><E><F><K><E><V><T><Q><E><D><F><K><G><S><W><N><V><V><C><F><Y><P><A><D><F><S><F><V><C><P><T><E><L><E><D><L><Q><N><Q><Y><A><K><L><Q><E><L><G><V><N><V><Y><S><V><S><T><D><T><H><F><V><H><K><A><W><H><D><H><S><D><A><I><S><K><L><E><Y><S><M><I><G><D><P><S><Q><T><I><T...
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.<BOP>
Q8CMQ2
Q50D79
UNC4_DANRE
Homeobox protein Uncx4.1
Danio
<M><M><D><S><R><I><L><E><H><P><H><A><Q><F><G><G><S><L><G><S><M><V><G><M><G><F><P><Y><H><L><G><H><H><H><V><Y><D><I><S><G><H><Q><L><Q><S><A><A><A><V><P><F><S><I><D><G><L><L><N><G><S><C><S><G><S><V><A><N><S><N><P><L><L><G><S><G><C><G><V><N><G><D><S><Q><Y><K><L><G><D><G><G><D><P><D><K><E><S><P><G><C><K><R><R><R><T><R><T><N...
Transcription factor involved in somitogenesis and neurogenesis.<BOP>
Q50D79
Q1RFX9
GLO2_ECOUT
Glyoxalase II
Escherichia
<M><N><L><N><S><I><P><A><F><D><D><N><Y><I><W><V><L><N><D><E><A><G><R><C><L><I><V><D><P><G><D><A><E><P><V><L><N><A><I><S><A><N><N><W><Q><P><E><A><I><F><L><T><H><H><H><H><D><H><V><G><G><V><K><E><L><V><E><K><F><P><Q><I><V><V><Y><G><P><Q><E><T><Q><D><K><G><T><T><Q><V><V><K><D><G><E><T><A><F><V><L><G><H><E><F><S><V><I><A><T...
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.<BOP>
Q1RFX9
B0TQ97
PNP_SHEHH
Polynucleotide phosphorylase
Shewanella
<M><V><H><V><N><P><I><V><K><S><F><E><Y><G><Q><H><T><V><T><L><E><T><G><V><I><A><R><Q><A><D><A><A><V><L><A><S><M><G><D><T><T><V><L><V><T><V><V><G><K><K><F><E><E><P><G><R><D><F><F><P><L><T><V><N><Y><Q><E><K><T><Y><A><A><G><K><I><P><G><G><F><F><K><R><E><G><R><P><S><E><G><E><T><L><T><A><R><L><I><D><R><P><I><R><P><L><F><P><N...
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.<BOP>
B0TQ97
Q39FP8
SURE2_BURL3
Nucleoside 5'-monophosphate phosphohydrolase 2
Burkholderia cepacia complex
<M><R><I><L><L><S><N><D><D><G><Y><L><A><P><G><L><A><A><L><S><D><A><L><Q><P><L><A><E><L><T><V><I><A><P><E><Q><N><C><S><G><A><S><N><S><L><T><L><S><R><P><L><S><V><Q><R><A><A><S><T><G><F><F><Y><V><N><G><T><P><T><D><S><V><H><V><A><L><T><G><M><A><D><A><R><P><D><L><V><V><S><G><I><N><N><G><Q><N><M><G><E><D><T><L><Y><S><G><T><V...
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.<BOP>
Q39FP8
Q0SPE1
RUVA_BORAP
Holliday junction ATP-dependent DNA helicase RuvA
Borreliella
<M><I><N><K><I><Y><G><K><V><I><E><K><K><E><S><S><L><V><L><M><T><A><V><F><E><F><E><L><L><V><S><A><F><C><L><A><N><F><K><L><L><D><K><V><E><L><F><T><Y><L><Y><T><K><E><N><E><L><K><L><F><G><F><L><N><S><D><E><R><E><T><F><K><S><L><I><G><V><S><G><I><G><P><R><A><A><L><R><V><L><S><N><I><R><Y><N><E><F><K><D><A><I><D><R><E><D><I><E...
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA...
Q0SPE1
C6C2E5
DBPB_BORBN
Decorin-binding protein B
Borreliella
<M><K><I><G><K><L><N><S><I><V><M><V><L><F><F><D><L><L><V><A><C><S><I><G><L><V><E><R><T><N><A><A><L><E><S><S><S><K><D><L><K><N><K><I><L><K><I><K><K><E><A><T><G><K><G><V><L><F><E><A><F><T><G><L><K><T><G><S><K><V><T><S><G><G><L><A><L><R><E><A><K><V><Q><A><I><V><E><T><G><K><F><L><K><I><I><E><E><E><A><L><K><L><K><E><T><G><N...
Binds to decorin which may mediate the adherence of B.burgdorferi to collagen fibers in skin and other tissues.<BOP>
C6C2E5
B0U4K2
NUSB_XYLFM
Antitermination factor NusB
Xylella
<M><S><K><V><S><G><G><G><P><C><P><R><R><R><D><G><V><D><P><A><L><R><S><R><A><R><R><R><A><L><Q><A><V><Y><A><W><Q><I><S><G><G><V><A><K><Q><V><I><A><H><F><A><H><E><Q><A><Y><E><V><A><D><L><V><Y><F><E><D><L><V><E><G><V><L><T><H><C><A><E><L><D><E><K><L><T><P><Y><L><D><R><T><I><E><E><V><D><A><I><E><R><A><V><L><R><L><G><A><Y><E...
Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.<BOP>
B0U4K2
Q97EX0
RSMA_CLOAB
S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase
Clostridium
<M><K><E><F><N><T><R><Q><I><V><E><K><Y><N><F><R><F><S><K><R><L><G><Q><N><F><L><T><D><N><T><V><L><D><D><I><V><E><N><A><E><I><Q><K><D><D><F><I><I><E><I><G><P><G><V><G><T><L><T><R><R><L><L><E><K><A><K><K><V><C><A><I><E><L><D><E><S><L><I><P><I><I><T><N><E><M><K><E><Y><D><N><F><T><L><I><H><N><D><A><L><K><V><D><F><N><N><I><I...
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.<BOP>
Q97EX0
A8G2H7
RSMH_PROM2
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Prochlorococcus
<M><Q><T><D><L><S><D><S><S><F><F><N><H><K><S><V><M><T><D><E><I><M><A><S><L><E><H><Y><P><L><I><H><N><N><Q><L><K><G><I><D><A><T><L><G><G><G><G><H><S><F><N><L><L><R><K><Y><S><E><L><N><I><I><G><L><D><Q><D><P><F><A><R><I><S><A><S><K><K><L><D><E><F><K><N><R><I><D><I><R><A><S><N><F><A><D><F><V><P><K><E><K><V><S><F><V><I><A><D...
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.<BOP>
A8G2H7
C1A1J0
RS20_RHOE4
30S ribosomal protein S20
Rhodococcus erythropolis group
<M><A><N><I><K><S><Q><V><K><R><I><R><T><N><E><A><A><R><L><R><N><Q><S><V><K><S><S><L><R><T><A><I><R><S><F><R><E><A><A><A><A><G><D><K><D><K><A><N><E><L><L><V><S><T><S><R><K><L><D><K><A><A><S><K><G><V><I><H><A><N><Q><A><A><N><K><K><S><A><L><S><Q><A><A><N><K><L>
Binds directly to 16S ribosomal RNA.<BOP>
C1A1J0
Q64680
CP2D4_RAT
Debrisoquine 4-hydroxylase
Rattus
<M><R><M><P><T><G><S><E><L><W><P><I><A><I><F><T><I><I><F><L><L><L><V><D><L><M><H><R><R><Q><R><W><T><S><R><Y><P><P><G><P><V><P><W><P><V><L><G><N><L><L><Q><I><D><F><Q><N><M><P><A><G><F><Q><K><L><R><C><R><F><G><D><L><F><S><L><Q><L><A><F><E><S><V><V><V><L><N><G><L><P><A><L><R><E><A><L><V><K><Y><S><E><D><T><A><D><R><P><P><L...
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.<BOP>
Q64680
Q5XC69
RF1_STRP6
Peptide chain release factor 1
Streptococcus
<M><N><I><Y><D><Q><L><Q><A><V><E><D><R><Y><E><E><L><G><E><L><L><S><D><P><D><V><V><S><D><T><K><R><F><M><E><L><S><R><E><E><A><N><T><R><E><T><V><T><A><Y><R><E><Y><K><Q><V><I><Q><T><I><S><D><A><E><E><M><I><K><D><A><S><G><D><P><E><L><E><E><M><A><K><E><E><L><K><E><S><K><A><A><K><E><E><Y><E><E><K><L><K><I><L><L><L><P><K><D><P...
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.<BOP>
Q5XC69
Q6KI81
ATPG_MYCMO
F-ATPase gamma subunit
Mesomycoplasma
<M><A><E><L><Q><K><L><S><S><R><L><K><S><V><K><V><T><R><K><I><T><K><A><M><E><L><V><A><A><S><K><I><R><R><A><K><E><S><F><F><S><N><K><E><Y><F><Q><I><I><Q><D><I><F><D><N><L><A><S><K><T><E><Q><I><F><L><K><K><Q><M><K><F><D><K><E><N><N><T><N><S><I><L><Y><I><V><I><N><S><D><L><G><L><C><G><A><Y><N><S><S><I><A><K><E><I><K><K><E><I...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.<BOP>
Q6KI81
A1R701
EFP_PAEAT
Elongation factor P
Paenarthrobacter
<M><A><T><T><N><D><I><K><N><G><T><V><L><K><L><E><G><Q><L><W><N><I><I><E><F><Q><H><V><K><P><G><K><G><G><A><F><V><R><T><K><M><R><N><V><M><S><G><K><V><V><D><K><T><F><N><A><G><L><K><I><E><T><A><T><V><D><R><R><D><Y><Q><Y><L><Y><Q><D><G><E><D><F><V><F><M><D><T><Q><D><Y><D><Q><I><T><V><S><G><A><T><V><G><D><A><T><N><F><M><L><E...
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP>
A1R701
Q4V622
CCH2R_DROME
Neuropeptide CCHamide-2 receptor
Sophophora
<M><Y><A><S><L><M><D><V><G><Q><T><L><A><A><R><L><A><D><S><D><G><N><G><A><N><D><S><G><L><L><A><T><G><Q><G><L><E><Q><E><Q><E><G><L><A><L><D><M><G><H><N><A><S><A><D><G><G><I><V><P><Y><V><P><V><L><D><R><P><E><T><Y><I><V><T><V><L><Y><T><L><I><F><I><V><G><V><L><G><N><G><T><L><V><I><I><F><F><R><H><R><S><M><R><N><I><P><N><T><Y...
Receptor for the neuropeptide CCHamide-2.<BOP>
Q4V622
Q8BVY0
RL1D1_MOUSE
Ribosomal L1 domain-containing protein 1
Mus
<M><K><G><S><A><S><E><S><P><S><A><S><V><A><E><A><T><T><T><D><V><Q><V><T><P><T><A><L><L><Q><L><D><R><E><Q><I><R><K><A><V><E><V><I><S><N><R><S><K><S><K><K><N><N><N><E><L><L><L><S><G><S><E><N><L><F><L><M><V><I><L><W><K><I><P><E><K><E><L><R><V><K><V><P><L><P><H><S><I><L><S><E><S><S><D><V><C><L><F><T><K><D><E><F><D><S><P><E...
Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.<BOP>
Q8BVY0
A1SU43
DER_PSYIN
GTP-binding protein EngA
Psychromonas
<M><L><P><V><V><A><L><V><G><R><P><N><V><G><K><S><T><L><F><N><R><L><T><R><T><R><D><A><L><V><A><D><F><P><G><L><T><R><D><R><K><Y><G><Q><A><K><I><D><E><H><E><F><I><V><I><D><T><G><G><I><T><G><D><E><E><G><I><D><A><L><M><A><G><Q><S><L><L><A><I><D><E><A><D><A><V><L><F><L><V><D><A><R><A><G><M><T><I><A><D><E><A><I><A><D><H><L><R...
GTPase that plays an essential role in the late steps of ribosome biogenesis.<BOP>
A1SU43
A1RJD1
UBIG_SHESW
3-demethylubiquinone 3-O-methyltransferase
Shewanella
<M><Q><H><N><T><N><V><D><P><Q><E><I><A><K><F><E><R><M><A><E><T><W><W><D><L><N><G><E><F><K><P><L><H><L><L><N><P><L><R><L><N><Y><I><D><Q><T><T><G><G><I><F><G><K><K><V><L><D><V><G><C><G><G><G><I><L><S><E><S><M><A><R><I><G><A><E><V><D><G><L><D><M><G><E><E><P><L><E><V><A><R><L><H><A><L><E><T><G><V><N><I><T><Y><V><K><N><T><A...
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP>
A1RJD1
P34641
CED11_CAEEL
Cell death protein 11
Caenorhabditis
<M><D><E><T><D><P><V><P><D><M><S><L><L><P><D><T><V><P><V><V><V><S><G><D><G><S><A><A><G><I><Q><L><C><P><A><L><I><L><G><S><P><Q><A><L><P><G><A><I><K><H><I><Y><S><R><L><A><A><A><A><S><E><V><D><Q><G><V><P><D><L><I><I><S><L><I><S><H><G><N><S><L><S><T><K><Y><M><S><S><V><E><N><G><L><K><S><F><L><I><G><C><G><T><W><L><I><S><S><G...
Plays a major role in programmed cell death.<BOP>
P34641
A1U1Y9
NQRE_MARN8
NQR-1 subunit E
Marinobacter
<M><E><H><Y><L><S><L><L><L><K><A><I><F><V><E><N><M><A><L><A><F><F><L><G><M><C><T><F><L><A><I><S><K><K><I><E><A><A><T><G><L><G><I><A><V><V><V><V><L><T><V><T><V><P><V><N><N><L><L><Y><N><T><I><L><R><E><G><A><L><D><W><A><G><L><P><N><V><D><L><S><F><L><G><L><L><T><Y><I><G><V><I><A><A><I><V><Q><I><M><E><M><V><L><D><K><Y><I><P...
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.<BOP>
A1U1Y9
P0ABS7
DNAG_SHIFL
DNA primase
Shigella
<M><A><G><R><I><P><R><V><F><I><N><D><L><L><A><R><T><D><I><V><D><L><I><D><A><R><V><K><L><K><K><Q><G><K><N><F><H><A><C><C><P><F><H><N><E><K><T><P><S><F><T><V><N><G><E><K><Q><F><Y><H><C><F><G><C><G><A><H><G><N><A><I><D><F><L><M><N><Y><D><K><L><E><F><V><E><T><V><E><E><L><A><A><M><H><N><L><E><V><P><F><E><A><G><S><G><P><S><Q...
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.<BOP>
P0ABS7
A4QA27
URED_CORGB
Urease accessory protein UreD
Corynebacterium
<M><T><Q><T><Q><P><V><G><T><L><R><L><T><I><D><D><Q><G><P><Q><G><Q><S><R><A><V><E><Q><F><H><Q><G><A><L><R><V><I><R><P><H><Y><L><D><D><S><G><Q><V><S><Y><T><I><I><A><I><G><G><G><Y><L><G><G><D><V><Y><E><Q><Q><F><T><V><K><D><N><A><K><A><L><I><T><T><Q><S><A><T><K><I><Y><R><T><P><Q><G><P><V><T><Q><Y><T><E><I><N><V><G><E><N><A...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
A4QA27
C1CSC8
ATPB_STRZT
F-ATPase subunit beta
Streptococcus
<M><S><S><G><K><I><A><Q><V><I><G><P><V><V><D><V><L><F><A><A><G><E><K><L><P><E><I><N><N><A><L><V><V><Y><K><N><D><E><R><K><T><K><I><V><L><E><V><A><L><E><L><G><D><G><M><V><R><T><I><S><M><E><S><T><D><G><L><T><R><G><M><E><V><L><D><T><G><R><P><I><S><V><P><V><G><K><E><T><L><G><R><V><F><N><V><L><G><D><T><I><D><L><E><A><P><F><T...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP>
C1CSC8
Q9XDP0
DSBI_LELAM
Protein-disulfide oxidoreductase DsbI
Lelliottia
<M><V><D><I><K><G><M><W><K><D><L><R><A><T><P><V><E><T><L><V><R><W><Q><E><Q><R><F><L><W><L><L><M><A><V><A><M><G><G><L><I><I><L><A><H><S><F><F><Q><I><Y><L><Y><M><A><P><C><E><Q><C><V><Y><I><R><F><A><M><F><V><M><V><F><G><G><L><I><A><A><I><N><P><K><N><I><I><L><K><L><I><G><C><L><A><A><F><Y><G><S><I><M><G><I><K><F><S><V><K><L...
Required for disulfide bond formation in some proteins. Part of a redox system composed of DsbI and DsbL that mediates formation of an essential disulfide bond in AssT.<BOP>
Q9XDP0
Q54824
DNRS_STRPE
2,3,6-trideoxy-3-aminohexose transferase
Streptomyces
<M><K><V><L><V><T><A><F><A><M><D><A><H><F><N><G><V><V><P><L><A><W><A><L><R><A><A><G><H><D><V><R><V><A><S><Q><P><A><L><T><D><S><I><T><R><A><G><L><T><A><V><P><V><G><T><D><H><Q><V><Q><A><A><M><G><A><M><A><P><G><V><F><A><L><H><L><N><P><D><Y><L><E><N><R><P><E><L><L><D><L><E><F><L><E><A><S><T><S><M><L><T><A><A><F><Y><A><Q><I...
Involved in the biosynthesis of the anthracyclines carminomycin and daunorubicin (daunomycin) which are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers. Catalyzes the addition of the TDP activated glycoside, L-daunosamine-TDP (2,3,6-tride...
Q54824
Q5PAY2
TRUB_ANAMM
tRNA-uridine isomerase
Anaplasma
<M><Q><S><A><R><V><K><Y><G><W><L><N><V><D><K><P><L><H><M><S><S><G><S><V><V><G><R><V><K><K><I><F><N><C><K><V><G><H><A><G><T><L><D><P><L><A><T><G><V><L><P><V><A><V><G><E><A><T><K><T><I><P><Y><A><V><D><G><L><K><S><Y><A><V><T><V><Q><W><G><S><Q><R><S><T><D><D><A><E><G><E><I><I><K><T><S><S><L><R><P><S><A><D><S><I><R><E><A><L...
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP>
Q5PAY2
Q06GR3
PSBZ_PIPCE
Photosystem II reaction center protein Z
Piper
<M><T><I><A><F><Q><L><A><V><F><A><L><I><A><T><S><L><I><L><V><I><G><V><P><V><V><F><A><S><P><D><G><W><S><S><N><K><N><I><V><F><S><G><T><S><L><W><I><G><L><V><F><L><V><G><I><L><N><S><L><I><S>
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.<BOP>
Q06GR3
P40988
FET4_YEAST
Low-affinity Fe(II) transport protein
Saccharomyces
<M><G><K><I><A><E><F><L><G><N><P><G><A><R><P><D><V><H><H><R><A><P><T><V><D><C><K><Q><Y><E><E><F><G><D><S><N><D><Y><K><N><D><D><V><V><R><V><V><S><H><S><D><E><S><T><D><D><E><L><C><N><V><N><L><T><E><T><G><A><I><F><T><S><K><G><F><T><G><L><S><K><G><F><T><D><K><T><L><D><F><L><V><R><V><A><G><S><Q><A><V><F><F><I><V><W><I><I><L...
Required for Fe(2+) ion low affinity uptake.<BOP>
P40988
P48169
GBRA4_HUMAN
GABA(A) receptor subunit alpha-4
Homo
<M><V><S><A><K><K><V><P><A><I><A><L><S><A><G><V><S><F><A><L><L><R><F><L><C><L><A><V><C><L><N><E><S><P><G><Q><N><Q><K><E><E><K><L><C><T><E><N><F><T><R><I><L><D><S><L><L><D><G><Y><D><N><R><L><R><P><G><F><G><G><P><V><T><E><V><K><T><D><I><Y><V><T><S><F><G><P><V><S><D><V><E><M><E><Y><T><M><D><V><F><F><R><Q><T><W><I><D><K><R...
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.<BOP>
P48169
Q214W4
PIMT_RHOPB
Protein-beta-aspartate methyltransferase
Rhodopseudomonas
<M><P><I><G><P><P><P><P><E><K><M><M><F><Q><L><S><L><R><R><R><G><I><S><D><Q><A><V><L><R><A><M><D><E><V><P><R><D><A><F><V><E><P><G><Q><R><A><E><A><W><L><D><T><A><L><P><I><A><C><G><Q><T><I><S><Q><P><F><V><V><A><Y><M><T><E><Q><M><Q><L><R><P><E><H><R><V><L><E><I><G><T><G><S><G><Y><Q><A><A><I><L><S><R><L><S><R><A><V><L><T><L...
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.<BOP>
Q214W4
A4IJK7
RL15_GEOTN
50S ribosomal protein L15
Geobacillus
<M><K><L><H><E><L><Q><P><A><P><G><S><R><K><K><A><V><R><V><G><R><G><I><G><S><G><N><G><K><T><A><G><R><G><H><K><G><Q><K><A><R><S><G><G><G><V><R><L><G><F><E><G><G><Q><T><P><L><F><R><R><L><P><K><R><G><F><T><N><I><N><R><K><E><Y><A><V><V><N><L><D><R><L><N><I><F><E><D><G><T><E><V><T><P><E><L><L><L><E><K><G><V><I><S><K><L><K><S...
Binds to the 23S rRNA.<BOP>
A4IJK7
A0A291NVT7
CESS1_CONMO
Conophysin
Strategoconus
<M><Q><M><G><R><P><T><L><L><P><C><L><L><L><L><L><V><L><S><T><Q><A><C><F><I><R><N><C><P><E><G><G><K><R><D><V><H><M><I><Q><P><T><K><P><C><M><N><C><S><F><G><Q><C><V><G><P><R><V><C><C><G><A><G><R><C><E><I><G><S><T><E><A><D><R><C><E><E><E><N><E><D><P><V><P><C><K><V><L><G><Q><H><C><V><L><N><N><P><G><N><V><N><G><N><C><V><D><G...
Targets vasopressin-oxytocin related receptors.<BOP>
A0A291NVT7
B2J1M7
MOAA_NOSP7
Molybdenum cofactor biosynthesis protein A
Nostoc
<M><N><Q><V><D><Y><L><R><I><S><L><I><D><R><C><N><F><R><C><Q><Y><C><M><P><E><G><V><E><L><D><Y><I><L><K><Q><Q><L><L><T><N><E><E><L><L><T><L><I><R><E><V><F><I><P><V><G><F><N><R><F><R><L><T><G><G><E><P><L><L><R><P><R><V><V><D><L><V><S><A><I><A><T><L><P><Q><T><Q><D><L><S><M><T><T><N><G><F><L><L><A><P><M><A><Q><N><L><Y><N><A...
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.<BOP>
B2J1M7
Q8E6W4
YIDC1_STRA3
Membrane protein YidC 1
Streptococcus
<M><K><K><K><L><K><T><F><S><L><I><L><L><T><G><S><L><L><V><A><C><G><R><G><E><V><S><S><H><S><A><T><L><W><E><Q><I><V><Y><A><F><A><K><S><I><Q><W><L><S><F><N><H><S><I><G><L><G><I><I><L><F><T><L><I><I><R><A><I><M><M><P><L><Y><N><M><Q><M><K><S><S><Q><K><M><Q><E><I><Q><P><R><L><K><E><L><Q><K><K><Y><P><G><K><D><P><D><S><R><L><K...
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.<BOP>
Q8E6W4
A8WHP3
SC5A9_DANRE
Solute carrier family 5 member 9
Danio
<M><P><A><S><P><E><P><V><T><A><T><P><E><P><E><E><V><P><A><K><F><T><L><E><A><A><D><I><A><V><V><V><V><Y><F><V><F><V><L><A><V><G><I><W><S><S><I><R><A><N><R><G><T><V><G><G><Y><F><L><A><G><R><S><M><T><W><W><P><I><G><A><S><L><M><S><S><N><V><G><S><G><L><F><I><G><L><A><G><T><G><A><A><G><G><L><A><V><G><G><F><E><W><N><A><A><W><V...
Probable sodium-dependent sugar transporter.<BOP>
A8WHP3
P29644
COX1_ATRSP
Cytochrome c oxidase polypeptide I
Atractosteus
<H><L><F><W><F><F><G><H><P><E><V><Y><I><L><I><L><P><G><F><G><M><I><S><H><I><V><A><Y><Y><A><G><K><K><E><P><F><G><Y><M><G><M><V><W><A><M><M><A><I><G><L><L><G><F><I><V><W><A><H><H><M><F><T><V><G><M><D><V><D><T><R><A><Y><F><T><S><A><T><M><I><I><A><I><P><T><G><V><K><V><F><S><W><L><A><T><L><H><G><G><S><I><K><W><D><T><P><L><L...
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII...
P29644
A4JAP1
RL4_BURVG
50S ribosomal protein L4
Burkholderia cepacia complex
<M><E><L><K><L><L><N><E><N><G><Q><E><G><A><V><V><N><A><S><D><V><V><F><G><R><D><Y><N><E><A><L><I><H><Q><V><V><V><A><Y><Q><A><N><A><R><Q><G><N><R><A><Q><K><D><R><E><Q><V><K><H><T><T><K><K><P><W><R><Q><K><G><T><G><R><A><R><A><G><M><S><S><S><P><L><W><R><G><G><G><R><I><F><P><N><S><P><E><E><N><F><S><H><K><V><N><K><K><M><H><R...
Forms part of the polypeptide exit tunnel.<BOP>
A4JAP1
C4ZF43
APT_AGARV
Adenine phosphoribosyltransferase
Lachnospiraceae incertae sedis
<M><K><T><V><K><D><Y><I><R><T><I><P><D><F><P><E><K><G><I><M><F><R><D><V><T><S><V><I><Q><D><A><D><G><L><K><L><A><I><D><E><M><I><K><R><L><D><G><L><D><F><D><V><I><A><G><A><E><S><R><G><F><V><F><G><M><P><I><A><Y><A><L><H><K><P><F><V><M><V><R><K><A><G><K><L><P><C><E><T><V><S><K><T><Y><D><L><E><Y><G><T><A><T><I><E><M><H><K><D...
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.<BOP>
C4ZF43
A5UBC8
FDHE_HAEIE
Protein FdhE homolog
Haemophilus
<M><S><I><K><I><L><S><E><S><E><I><K><Q><V><A><N><S><Y><Q><A><P><A><V><L><F><A><N><P><K><N><L><Y><Q><R><R><A><K><R><L><R><D><L><A><Q><N><H><P><L><S><D><Y><L><L><F><A><A><D><I><V><E><S><Q><L><S><T><L><E><K><N><P><L><P><P><Q><Q><L><E><Q><L><N><A><I><E><P><L><N><A><K><T><F><K><R><D><S><I><W><R><E><Y><L><T><E><I><L><D><E><I...
Necessary for formate dehydrogenase activity.<BOP>
A5UBC8
Q8NS92
PDXR_CORGL
HTH-type pyridoxine biosynthesis transcriptional regulator PdxR
Corynebacterium
<M><L><A><D><L><P><I><A><L><N><P><H><E><P><T><S><I><P><T><Q><L><T><E><Q><I><R><R><L><V><A><R><G><I><L><T><P><G><D><P><L><P><S><S><R><S><L><S><T><Q><L><G><V><S><R><G><S><V><V><T><A><Y><D><Q><L><A><G><E><G><Y><L><S><T><A><R><G><S><G><T><T><I><N><P><D><L><H><L><L><K><P><V><E><I><E><K><K><E><T><S><R><S><V><P><P><P><L><L><N...
May have a regulatory function in pyridoxine biosynthesis. Is said to also have an aminotransferase activity in valine biosynthesis as a double inactivation of ilvE and pdxR results in an auxotrophic requirement for valine.<BOP>
Q8NS92
A8G3Q9
CHLB_PROM2
Light-independent protochlorophyllide reductase subunit B
Prochlorococcus
<M><E><L><T><L><W><T><Y><E><G><P><P><H><V><G><A><M><R><I><A><S><S><M><K><D><I><H><Y><V><L><H><A><P><Q><G><D><T><Y><A><D><L><L><F><T><M><I><E><R><R><G><Q><R><P><P><V><T><Y><T><T><F><Q><A><R><D><L><G><G><D><T><A><E><L><V><K><K><N><I><K><E><A><V><E><R><F><K><P><K><T><L><L><V><G><E><S><C><T><A><E><L><I><Q><D><Q><P><G><A><L...
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex.<BOP>
A8G3Q9
Q317V2
PYRG_PROM9
UTP--ammonia ligase
Prochlorococcus
<M><S><K><F><V><F><V><T><G><G><V><V><S><S><I><G><K><G><I><V><A><A><S><L><G><R><L><L><K><S><R><G><Y><S><V><S><I><L><K><L><D><P><Y><L><N><V><D><P><G><T><M><S><P><F><Q><H><G><E><V><F><V><T><E><D><G><A><E><T><D><L><D><L><G><H><Y><E><R><F><T><D><T><A><M><T><R><L><N><S><V><T><T><G><S><I><Y><Q><A><V><I><N><K><E><R><R><G><S><Y...
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.<BOP>
Q317V2
Q3UP24
NLRC4_MOUSE
Ice protease-activating factor
Mus
<M><N><F><I><R><N><N><R><R><A><L><I><Q><R><M><G><L><T><V><T><K><Q><I><C><D><D><L><F><A><L><N><V><L><N><N><Q><E><A><N><V><I><Y><C><E><P><L><E><Q><E><A><A><R><K><I><I><H><M><T><M><Q><K><G><S><A><A><C><N><L><F><L><K><S><L><E><N><W><D><Y><F><V><Y><Q><D><L><T><G><Q><N><L><S><Y><Q><V><T><E><E><D><L><N><V><L><A><Q><N><L><K><D...
Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis. The NLRC4 inflammasome is activated as part of the innate immune response to a ...
Q3UP24
Q9K8E8
LEU1_HALH5
Alpha-isopropylmalate synthase
Halalkalibacterium (ex Joshi et al. 2022)
<M><R><K><I><S><V><F><D><T><T><L><R><D><G><E><Q><S><A><G><V><N><L><N><F><E><E><K><M><E><I><A><K><Q><L><E><R><L><G><V><D><I><I><E><A><G><F><P><A><S><S><Q><G><D><F><Q><S><V><K><A><I><A><E><T><V><K><G><S><S><V><T><G><L><A><R><S><V><Q><K><D><I><D><A><A><W><E><A><L><K><S><A><E><E><P><R><I><H><L><F><I><A><T><S><P><I><H><M><E...
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).<BOP>
Q9K8E8
C6BYQ6
RL31_MARSD
50S ribosomal protein L31
Maridesulfovibrio
<M><K><K><D><I><H><P><K><L><H><K><A><T><V><R><C><H><C><G><Y><E><S><E><L><Y><S><T><I><G><E><E><V><S><T><E><I><C><S><N><C><H><P><F><Y><T><G><K><Q><R><F><V><D><T><A><G><R><I><D><R><F><K><K><K><F><A><N><F><D><A><A><S><K><V><K><G><N>
Binds the 23S rRNA.<BOP>
C6BYQ6
C1A3W7
GUAA_GEMAT
Glutamine amidotransferase
Gemmatimonas
<M><N><S><R><I><L><I><L><D><C><G><S><Q><F><T><Q><L><I><A><R><R><V><R><E><A><R><V><Y><S><E><I><H><P><P><T><K><S><L><D><W><I><R><A><W><K><P><T><G><I><I><L><S><G><G><P><S><S><V><T><D><E><G><A><P><T><I><P><P><A><L><L><D><V><A><P><V><L><G><V><C><Y><G><M><Q><L><I><A><H><L><E><G><G><S><V><V><G><G><G><R><R><E><Y><G><R><A><E><V...
Catalyzes the synthesis of GMP from XMP.<BOP>
C1A3W7
Q6B8V3
RK3_GRATL
50S ribosomal protein L3, chloroplastic
Agarophyton tenuistipitatum
<M><K><I><G><L><L><G><K><K><I><G><M><T><Q><I><F><D><P><G><G><K><A><L><P><V><T><I><L><K><L><G><P><C><L><I><T><D><I><K><K><M><E><S><H><G><Y><A><A><I><Q><I><G><Y><V><K><V><N><G><N><K><L><N><K><A><Q><I><G><H><L><N><K><Y><N><M><P><L><V><K><F><L><K><E><Y><K><V><A><S><T><E><N><Y><Q><I><G><K><W><I><T><V><E><D><L><S><I><N><Q><N...
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP>
Q6B8V3
Q5VVP1
S31A6_HUMAN
Protein FAM75A6
Homo
<M><E><N><L><P><F><P><L><K><L><L><S><A><S><S><L><N><A><P><S><S><T><P><W><V><L><D><I><F><L><T><L><V><F><A><L><G><F><F><F><L><L><L><P><Y><L><S><Y><F><H><C><D><D><P><P><S><P><S><P><G><K><R><K><C><P><V><G><R><R><R><R><P><R><G><R><M><K><N><H><S><L><R><A><G><R><E><C><P><R><G><L><E><E><T><S><D><L><L><S><Q><L><Q><S><L><L><G><P...
May play a role in spermatogenesis.<BOP>
Q5VVP1
A0B8A0
DGGGP_METTP
Geranylgeranylglycerol-phosphate geranylgeranyltransferase
Methanothrix
<M><T><L><L><E><I><M><R><P><A><N><C><V><M><A><G><A><A><S><L><T><G><M><L><V><S><G><A><L><L><Q><S><L><H><T><P><V><L><V><F><S><A><V><L><L><I><T><G><G><G><N><A><I><N><D><Y><F><D><R><E><I><D><A><V><N><R><P><D><R><P><I><P><S><G><R><I><S><P><R><A><A><L><I><W><S><V><A><L><F><I><A><G><C><L><I><A><G><L><I><N><Q><S><C><L><A><L><A...
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.<BOP>
A0B8A0
B3DQ62
DXR_BIFLD
2-C-methyl-D-erythritol 4-phosphate synthase
Bifidobacterium
<M><S><I><A><S><N><S><T><V><I><I><L><G><S><T><G><S><I><G><T><Q><G><L><D><V><I><S><R><H><P><E><R><F><T><V><T><G><L><A><A><G><G><A><H><I><E><L><L><A><Q><Q><A><A><Q><F><H><V><S><E><A><A><V><F><D><E><T><K><V><P><A><L><Q><A><A><L><A><Q><A><G><A><Q><G><V><R><V><T><G><G><P><D><S><V><I><A><M><A><G><S><G><A><N><V><V><L><N><G><I...
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
B3DQ62
Q9GZV3
SC5A7_HUMAN
Solute carrier family 5 member 7
Homo
<M><A><F><H><V><E><G><L><I><A><I><I><V><F><Y><L><L><I><L><L><V><G><I><W><A><A><W><R><T><K><N><S><G><S><A><E><E><R><S><E><A><I><I><V><G><G><R><D><I><G><L><L><V><G><G><F><T><M><T><A><T><W><V><G><G><G><Y><I><N><G><T><A><E><A><V><Y><V><P><G><Y><G><L><A><W><A><Q><A><P><I><G><Y><S><L><S><L><I><L><G><G><L><F><F><A><K><P><M><R...
Transmembrane transporter that imports choline from the extracellular space into the neuron with high affinity. Choline uptake is the rate-limiting step in acetylcholine synthesis. Sodium ion- and chloride ion-dependent.<BOP>
Q9GZV3
Q8BK72
RT27_MOUSE
Mitochondrial ribosomal protein S27
Mus
<M><A><A><P><M><V><R><C><G><M><L><L><A><R><R><L><D><A><S><R><L><C><L><A><G><K><R><C><L><L><S><A><A><Y><V><D><S><H><Q><W><E><A><R><E><K><E><E><Y><H><L><A><D><L><A><S><L><M><D><K><A><Y><E><R><K><L><P><V><S><S><L><S><I><S><R><F><V><D><N><I><A><S><R><E><D><L><D><S><A><E><Y><Y><L><Y><K><F><R><H><S><P><N><C><W><Y><L><R><D><W...
RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis. Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain. Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu). Overexpressed ...
Q8BK72
Q04EY4
ECFA3_OENOB
Energy-coupling factor transporter ATP-binding protein EcfA3
Oenococcus
<M><E><I><N><F><R><N><V><S><F><S><Y><Q><L><N><T><P><F><S><T><A><A><L><K><D><V><S><F><D><I><P><D><G><S><F><T><S><I><V><G><H><T><G><S><G><K><S><T><V><L><Q><L><I><D><G><L><L><I><P><E><K><G><H><I><Q><A><G><S><F><Q><M><N><S><G><S><N><A><K><H><L><K><K><F><R><K><N><V><G><F><I><F><Q><F><S><E><N><Q><L><F><E><E><T><V><E><K><D><L...
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.<BOP>
Q04EY4
Q6MNY2
PDRP_BDEBA
Putative pyruvate, phosphate dikinase regulatory protein
Bdellovibrio
<M><D><G><D><N><K><T><Y><T><I><Y><I><L><S><D><S><T><G><E><T><A><A><T><M><I><R><A><A><L><V><Q><Y><T><T><K><D><V><N><I><I><R><C><K><N><V><R><T><D><T><Q><A><E><A><V><I><E><E><C><F><E><R><R><G><M><L><A><Y><T><V><A><S><Q><G><L><R><A><K><I><R><E><M><A><S><G><K><G><I><P><Y><F><D><L><L><G><P><L><L><S><T><L><D><T><F><F><G><Q><H...
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.<BOP>
Q6MNY2
Q9SEH5
PMT3_TOBAC
Putrescine N-methyltransferase 3
Nicotiana
<M><E><V><I><S><T><N><T><N><G><S><T><I><F><K><N><G><A><I><P><M><N><G><Y><Q><N><G><T><S><K><H><Q><N><G><H><Q><N><G><T><S><E><H><R><N><G><H><Q><N><G><I><S><E><H><Q><N><G><H><Q><N><G><T><S><E><H><Q><N><G><H><Q><N><G><T><I><S><H><D><N><G><N><E><L><Q><L><L><G><S><S><N><S><I><K><P><G><W><F><S><E><F><S><A><L><W><P><G><E><A><F...
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinoge...
Q9SEH5
Q75KA9
CCS1_ORYSJ
C-type cytochrome synthesis protein 1
Oryza sativa
<M><P><S><P><T><C><Y><L><L><L><N><P><T><A><S><R><S><H><H><R><P><R><L><P><L><P><A><A><A><P><P><R><R><R><V><H><V><S><C><D><A><R><R><T><G><G><G><G><G><G><G><G><V><K><R><E><A><I><P><A><G><T><G><K><A><K><K><Q><V><V><F><F><D><A><A><P><P><V><S><Q><R><G><G><G><G><G><G><E><G><E><G><E><G><E><G><E><G><K><V><A><R><R><K><E><N><A><A...
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.<BOP>
Q75KA9
Q92561
PHYIP_HUMAN
Phytanoyl-CoA hydroxylase-associated protein 1
Homo
<M><E><L><L><S><T><P><H><S><I><E><I><N><N><I><T><C><D><S><F><R><I><S><W><A><M><E><D><S><D><L><E><R><V><T><H><Y><F><I><D><L><N><K><K><E><N><K><N><S><N><K><F><K><H><R><D><V><P><T><K><L><V><A><K><A><V><P><L><P><M><T><V><R><G><H><W><F><L><S><P><R><T><E><Y><S><V><A><V><Q><T><A><V><K><Q><S><D><G><E><Y><L><V><S><G><W><S><E><T...
Its interaction with PHYH suggests a role in the development of the central system.<BOP>
Q92561
A0L8Q7
PYRH_MAGMM
Uridine monophosphate kinase
Magnetococcus
<M><D><V><A><R><A><K><R><V><L><L><K><L><S><G><E><A><L><M><G><E><Q><A><Y><G><I><A><P><E><F><L><S><Y><L><V><E><E><V><Q><S><A><I><A><L><D><I><E><L><A><L><V><I><G><G><G><N><I><F><R><G><I><S><G><S><A><N><G><M><G><R><T><R><A><D><Q><M><G><M><L><A><T><V><I><N><G><L><A><L><Q><S><A><L><M><L><S><G><T><E><A><V><V><Q><T><A><L><E><M...
Catalyzes the reversible phosphorylation of UMP to UDP.<BOP>
A0L8Q7
Q3B4Y9
RNY_CHLL3
Ribonuclease Y
Pelodictyon
<M><G><I><V><I><N><L><F><L><I><I><F><A><S><V><V><F><F><A><A><G><F><F><L><G><R><F><F><L><E><R><L><G><T><T><K><V><L><E><A><E><E><R><A><V><Q><I><V><Q><E><A><Q><K><E><A><N><E><Y><K><E><L><K><V><T><E><V><N><Q><E><W><K><K><K><R><R><E><F><D><Q><E><V><V><I><K><N><N><K><F><N><Q><L><Q><K><Q><V><Q><Q><R><E><A><Q><L><K><K><Q><L><Q...
Endoribonuclease that initiates mRNA decay.<BOP>
Q3B4Y9
P05123
KCRM_CANLF
M-CK
Canis
<M><P><F><G><N><T><H><N><K><F><K><L><N><Y><K><P><E><E><E><Y><P><D><L><T><K><H><N><N><H><M><A><K><A><L><T><P><E><I><Y><K><K><L><R><D><K><E><T><P><S><G><F><T><L><D><D><V><I><Q><T><G><V><D><N><P><G><H><P><F><I><M><T><V><G><C><V><A><G><D><E><E><S><Y><Q><V><F><K><D><L><F><D><P><I><I><Q><D><R><H><G><G><Y><K><P><T><D><K><H><K...
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.<BOP>
P05123
Q95741
CYB_ARTOB
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Artibeus
<M><T><N><I><R><K><T><H><P><L><L><K><I><I><N><S><S><F><V><D><L><P><A><P><S><S><L><S><S><W><W><N><F><G><S><L><L><G><V><C><L><G><V><Q><I><L><T><G><L><F><L><A><M><H><Y><T><S><D><T><A><T><A><F><N><S><V><T><H><I><C><R><D><V><N><Y><G><W><L><L><R><Y><L><H><A><N><G><A><S><M><F><F><I><C><L><Y><L><H><V><G><R><G><L><Y><Y><G><S><Y...
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is...
Q95741
Q7W183
LOLB_BORPA
Outer-membrane lipoprotein LolB
Bordetella
<M><S><V><C><P><A><P><R><S><P><V><R><W><L><H><A><F><T><L><C><L><L><L><A><V><L><A><G><C><V><S><V><P><K><P><M><A><G><A><G><E><D><V><F><S><R><V><G><R><F><A><I><T><V><T><E><S><D><G><K><Q><Q><A><V><Q><G><G><F><A><W><R><D><D><G><G><S><Y><L><L><D><L><T><N><P><L><G><S><T><E><A><R><V><E><G><R><P><G><M><A><V><L><T><R><A><N><G><E...
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.<BOP>
Q7W183
Q47W53
UPP_COLP3
UPRTase
Colwellia
<M><S><V><F><E><I><K><H><P><L><V><Q><H><K><I><S><L><M><R><A><K><D><M><S><T><R><S><F><R><Q><L><S><A><E><V><G><S><L><L><T><Y><E><A><T><K><D><L><E><L><E><N><F><Q><M><E><G><W><D><G><E><I><T><G><Q><R><L><V><G><K><K><A><T><V><V><P><I><L><R><A><G><I><G><M><L><D><G><V><L><E><L><M><P><S><A><K><I><S><V><V><G><L><Y><R><D><E><E><T...
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP>
Q47W53
A4FWL3
RS11_METM5
30S ribosomal protein S11
Methanococcus
<M><S><Q><K><W><G><L><V><H><I><Y><A><S><Y><N><N><T><I><L><H><V><T><D><L><T><G><A><E><T><I><A><K><V><S><G><G><M><I><V><R><N><Q><R><D><E><S><S><P><Y><A><A><M><Q><A><A><F><K><I><A><D><L><M><R><D><K><G><I><D><Q><V><H><V><K><V><R><A><T><G><G><Q><K><S><K><N><P><G><P><G><A><Q><A><A><I><R><A><L><S><R><A><G><I><R><I><G><R><I><E...
Located on the platform of the 30S subunit.<BOP>
A4FWL3
Q0SX30
DEOC_SHIF8
Phosphodeoxyriboaldolase
Shigella
<M><T><D><L><K><A><S><S><L><R><A><L><K><L><M><D><L><T><T><L><N><D><D><D><T><D><E><K><V><I><A><L><C><H><Q><A><K><T><P><V><G><N><T><A><A><I><C><I><Y><P><R><F><I><P><I><A><R><K><T><L><K><E><Q><G><T><P><E><I><R><I><A><T><V><T><N><F><P><H><G><N><D><D><I><E><I><A><L><A><E><T><R><A><A><I><A><Y><G><A><D><E><V><D><V><V><F><P><Y...
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.<BOP>
Q0SX30
P53552
THO2_YEAST
Zinc-regulated gene 13 protein
Saccharomyces
<M><A><E><Q><T><L><L><S><K><L><N><A><L><S><Q><K><V><I><P><P><A><S><P><S><Q><A><S><I><L><T><E><E><V><I><R><N><W><P><E><R><S><K><T><L><C><S><D><F><T><A><L><E><S><N><D><E><K><E><D><W><L><R><T><L><F><I><E><L><F><D><F><I><N><K><N><D><E><N><S><P><L><K><L><S><D><V><A><S><F><T><N><E><L><V><N><H><E><R><Q><V><S><Q><A><S><I><V><G...
Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export. The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription. THO is important for stabilizing nascent RNA in the RNA polymerase II elon...
P53552
F1Q4R9
MEOX1_DANRE
Protein choker
Danio
<M><E><Q><S><A><S><S><C><M><R><S><P><H><T><G><G><A><L><W><G><C><V><R><S><P><H><S><G><G><S><G><A><G><I><Q><P><Y><Q><Q><A><P><F><A><L><H><Q><K><H><D><F><L><A><Y><T><D><F><S><S><S><C><L><V><P><A><P><H><A><Y><P><R><E><D><R><L><Y><P><E><T><H><S><G><Y><Q><R><T><E><W><Q><F><S><P><C><E><P><R><G><R><G><Q><E><P><C><Q><G><A><A><E...
Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Required for...
F1Q4R9
Q6F1W5
ECFA1_MESFL
Energy-coupling factor transporter ATP-binding protein EcfA1
Mesoplasma
<M><D><S><L><K><K><F><K><T><T><K><L><T><S><Q><D><L><N><D><F><K><I><K><L><H><A><K><Y><I><E><M><L><E><A><N><N><N><F><F><K><F><K><E><A><E><K><Q><G><K><I><S><K><E><E><L><V><E><Y><K><N><K><S><I><K><A><K><K><A><F><K><A><I><C><Q><D><K><S><F><S><E><N><L><K><N><I><T><K><I><Y><N><S><T><T><R><K><N><S><S><V><I><L><E><Q><A><K><E><E...
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.<BOP>
Q6F1W5
Q8CFK6
DEN1C_MOUSE
Connecdenn 3
Mus
<M><G><S><T><E><T><R><H><P><P><A><M><F><D><W><F><F><E><A><G><C><P><N><S><L><E><E><D><P><P><I><L><R><Q><F><P><P><D><F><Q><E><Q><E><A><M><Q><M><V><P><R><F><C><F><P><F><D><I><E><R><E><P><P><S><P><A><V><Q><H><F><T><F><A><L><T><D><L><V><G><N><R><R><F><G><F><C><R><L><R><A><G><A><R><S><C><L><C><I><L><S><H><F><P><W><F><E><V><F...
Guanine nucleotide exchange factor (GEF) which may activate RAB8A, RAB13 and RAB35. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.<BOP>
Q8CFK6
Q9ZKX5
CATA_HELPJ
Catalase
Helicobacter
<M><V><N><K><D><V><K><Q><T><T><A><F><G><A><P><V><W><D><D><N><N><V><I><T><A><G><P><R><G><P><V><L><L><Q><S><T><W><F><L><E><K><L><A><A><F><D><R><E><R><I><P><E><R><V><V><H><A><K><G><S><G><A><Y><G><T><F><T><V><T><K><D><I><T><K><Y><T><K><A><K><I><F><S><K><V><G><K><K><T><E><C><F><F><R><F><S><T><V><A><G><E><K><G><S><A><D><A><V...
Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide.<BOP>
Q9ZKX5
Q65TI7
RL25_MANSM
50S ribosomal protein L25
Basfia
<M><A><F><K><F><N><A><E><V><R><S><A><Q><G><K><G><A><S><R><R><L><R><H><N><G><Q><I><P><A><I><V><Y><G><G><N><E><D><A><V><S><I><V><L><N><H><D><E><L><N><N><A><Q><A><H><D><S><F><Y><S><E><V><I><T><L><V><I><N><G><K><E><V><A><V><K><V><Q><A><M><Q><R><H><P><F><K><P><K><L><V><H><I><D><F><K><R><A>
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.<BOP>
Q65TI7
P24343
HXD12_CHICK
Homeobox protein Hox-4F
Gallus
<M><C><D><R><S><L><Y><R><S><G><Y><V><G><S><L><L><N><L><Q><S><P><D><S><F><Y><F><P><N><L><R><A><N><G><S><Q><L><A><A><L><P><T><I><S><Y><P><R><S><S><I><P><W><T><C><P><S><P><C><A><A><Q><P><Q><G><H><A><F><G><G><A><A><Q><P><Y><L><P><G><S><V><P><I><S><I><S><S><N><S><N><K><E><C><L><E><E><N><S><K><Y><Y><A><H><D><A><S><S><K><Q><E...
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.<BOP>
P24343
B2GIZ5
RL23_KOCRD
50S ribosomal protein L23
Kocuria
<M><S><V><I><Y><N><K><D><P><R><D><V><I><I><R><P><V><V><S><E><K><S><Y><G><L><I><D><E><G><K><Y><T><F><Q><V><D><P><S><A><N><K><T><E><I><K><Y><A><I><E><H><I><F><G><V><K><V><A><S><V><N><T><L><N><R><P><G><K><R><K><R><T><R><F><G><W><G><Q><R><K><A><T><K><R><A><V><V><S><L><R><E><G><S><I><D><I><F><G><G><P><L><S>
One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.<BOP>
B2GIZ5
Q9ESY9
GILT_MOUSE
Lysosomal thiol reductase IP30
Mus
<M><S><W><S><P><I><L><P><F><L><S><L><L><L><L><L><F><P><L><E><V><P><R><A><A><T><A><S><L><S><Q><A><S><S><E><G><T><T><T><C><K><A><H><D><V><C><L><L><G><P><R><P><L><P><P><S><P><P><V><R><V><S><L><Y><Y><E><S><L><C><G><A><C><R><Y><F><L><V><R><D><L><F><P><T><W><L><M><V><M><E><I><M><N><I><T><L><V><P><Y><G><N><A><Q><E><R><N><V><S...
Lysosomal thiol reductase that can reduce protein disulfide bonds. May facilitate the complete unfolding of proteins destined for lysosomal degradation. Plays an important role in antigen processing. Facilitates the generation of MHC class II-restricted epitodes from disulfide bond-containing antigen by the endocytic r...
Q9ESY9
A6WK72
PURT_SHEB8
Phosphoribosylglycinamide formyltransferase 2
Shewanella
<M><I><G><T><P><Y><T><E><G><A><R><R><A><M><L><L><G><C><G><E><L><G><K><E><V><A><I><E><L><Q><R><L><G><V><E><V><I><G><V><D><R><Y><A><N><A><P><A><M><Q><V><A><H><R><S><H><V><I><N><M><L><D><A><N><A><L><R><A><V><I><E><L><E><K><P><H><L><V><I><P><E><I><E><A><I><A><T><Q><T><L><V><D><M><E><A><E><G><V><N><I><I><P><T><A><R><A><T><K...
Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.<BOP>
A6WK72
A4WEI9
UPPP_ENT38
Undecaprenyl pyrophosphate phosphatase
Enterobacter
<M><S><D><M><H><S><L><L><V><A><A><I><L><G><V><V><E><G><L><T><E><F><L><P><V><S><S><T><G><H><M><I><I><V><G><H><L><L><G><F><E><G><E><T><A><K><T><F><E><V><V><I><Q><L><G><S><I><L><A><V><V><V><M><F><W><R><R><L><F><G><L><I><G><I><H><F><G><R><P><P><Q><H><E><G><E><G><K><G><R><L><T><L><I><H><I><L><L><G><M><V><P><A><V><V><L><G><L...
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP>
A4WEI9
A0PP03
BIOD_MYCUA
Dethiobiotin synthase
Mycobacterium
<M><T><V><L><C><V><T><G><T><C><T><G><V><G><K><T><V><V><T><A><A><L><A><S><Q><A><N><Q><A><G><I><D><V><V><V><C><K><P><V><Q><T><G><T><G><N><G><D><D><D><L><A><E><I><G><R><L><S><G><V><T><E><L><V><G><L><A><R><Y><P><L><P><M><A><P><V><A><A><A><E><Q><A><G><Q><P><L><P><S><R><D><Q><L><V><Q><H><I><R><G><L><D><R><P><G><R><L><T><L><V...
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.<BOP>
A0PP03
Q8P4H2
RPOD_XANCP
Sigma-70
Xanthomonas
<M><A><N><E><R><P><A><Q><Q><S><D><I><K><L><L><I><S><K><G><L><E><Q><G><Y><L><T><Y><A><E><V><N><D><H><L><P><D><D><L><V><D><P><E><Q><I><E><D><I><I><S><M><I><N><G><M><G><I><D><V><H><E><V><A><P><D><A><E><T><L><L><L><N><D><G><N><T><G><N><R><E><V><D><D><T><A><A><E><E><A><A><A><A><L><T><A><L><D><T><E><G><G><R><T><T><D><P><V><R...
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.<BOP>
Q8P4H2
B0BUJ0
RL20_RICRO
50S ribosomal protein L20
spotted fever group
<M><T><R><A><K><S><G><K><I><S><K><N><R><H><K><K><I><L><K><L><A><K><G><Y><R><G><R><A><N><S><C><F><R><V><A><I><E><K><V><E><K><A><L><Q><Y><A><Y><R><D><R><R><N><R><K><R><D><F><R><G><L><W><I><Q><R><I><N><A><A><V><R><E><H><G><L><V><Y><S><Q><F><M><G><A><L><K><K><T><E><I><A><I><D><R><K><V><L><A><E><L><A><V><N><N><S><D><G><F><V...
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.<BOP>
B0BUJ0
P67084
PLPHP_MYCBO
Pyridoxal phosphate homeostasis protein
Mycobacterium tuberculosis complex
<M><A><A><D><L><S><A><Y><P><D><R><E><S><E><L><T><H><A><L><A><A><M><R><S><R><L><A><A><A><A><E><A><A><G><R><N><V><G><E><I><E><L><L><P><I><T><K><F><F><P><A><T><D><V><A><I><L><F><R><L><G><C><R><S><V><G><E><S><R><E><Q><E><A><S><A><K><M><A><E><L><N><R><L><L><A><A><A><E><L><G><H><S><G><G><V><H><W><H><M><V><G><R><I><Q><R><N><K...
Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.<BOP>
P67084
P82292
Z13_BOVIN
Spermadhesin Z13
Bos
<D><S><T><D><G><L><L><V><K><D><K><Y><L><C><G><D><L><Y><G><E><E><Y><G><V><I><F><P><Y><L><G><L><K><T><E><C><L><W><T><I><K><M><D><P><L><Y><R><I><L><L><T><V><R><D><V><H><E><N><C><N><K><E><S><L><E><I><I><E><G><P><P><E><S><S><N><S><R><K><I><C><D><T><S><H><A><E><Y><T><S><C><T><N><T><M><T><V><K><Y><T><R><K><P><N><H><P><A><P><D...
May be involved in the fertilization process.<BOP>
P82292
Q8DI06
SURE_THEVB
Nucleoside 5'-monophosphate phosphohydrolase
Thermosynechococcus
<M><R><L><L><I><A><N><D><D><G><V><F><A><P><G><I><R><T><L><A><D><T><L><A><I><A><G><H><E><V><V><V><V><C><P><D><R><E><R><S><A><T><G><H><S><L><T><V><F><D><P><I><R><A><E><V><V><S><D><R><F><H><P><R><I><K><A><W><A><C><S><G><T><P><S><D><C><V><K><L><A><L><G><A><L><L><E><Q><P><P><D><F><V><V><S><G><I><N><Q><G><S><N><L><G><T><D><I...
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.<BOP>
Q8DI06
Q822I4
EFTU_CHLCV
Elongation factor Tu
Chlamydia
<M><S><K><E><T><F><Q><R><N><K><P><H><I><N><I><G><T><I><G><H><V><D><H><G><K><T><T><L><T><A><A><I><T><R><A><L><S><A><E><G><L><A><N><F><C><D><Y><S><S><I><D><N><T><P><E><E><K><A><R><G><I><T><I><N><A><S><H><V><E><Y><E><T><P><N><R><H><Y><A><H><V><D><C><P><G><H><A><D><Y><V><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V><V><S...
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP>
Q822I4
Q750S3
PUS5_ASHGO
Uracil hydrolyase PUS5
Eremothecium
<M><N><R><W><A><V><P><I><L><H><E><H><K><H><Y><Y><I><V><N><K><V><H><G><I><V><C><Q><P><P><D><L><R><T><W><Y><K><Y><H><D><Y><E><P><P><V><L><L><D><L><L><R><K><Q><H><P><N><F><G><G><E><V><W><R><T><V><H><R><L><D><E><P><V><T><G><G><V><L><V><S><R><N><K><R><A><A><A><M><F><S><R><S><L><A><L><G><G><N><R><G><F><P><L><T><R><R><Y><V><A...
Pseudouridylate synthase responsible for the pseudouridine-2819 formation in mitochondrial 21S rRNA. May modulate the efficiency or the fidelity of the mitochondrial translation machinery.<BOP>
Q750S3
A1XIM1
MEP3_TRISD
Fungalysin MEP3
Trichophyton
<H><N><V><V><D><Y><V><A><S><A><E><Y><K><V><F><A><W><G><L><N><D><P><T><E><G><N><P><T><S><I><R><D><P><W><T><D><A><S><P><Y><T><W><N><S><D><G><M><S><K><Y><P><T><T><R><G><N><N><A><I><A><Q><D><N><P><T><G><G><S><T><Y><I><N><N><Y><R><P><Q><S><P><N><L><I><F><S><Y><P><W><S><P><T><A><T><P><P><S><S><Y><K><D><F><S><I><T><Q><L><F><Y...
Secreted metalloproteinase probably acting as a virulence factor.<BOP>
A1XIM1
B7KUT4
NRDR_METC4
Transcriptional repressor NrdR
Methylorubrum
<M><R><C><P><F><C><G><G><P><D><T><Q><V><K><D><S><R><P><S><E><D><S><S><A><I><R><R><R><R><V><C><P><D><C><G><G><R><F><T><T><F><E><R><V><Q><L><R><E><L><V><V><L><K><R><S><G><K><R><V><P><F><D><R><D><K><L><Q><R><S><I><D><V><A><L><R><K><R><T><V><D><P><E><R><V><E><R><L><V><S><G><I><T><R><R><L><E><S><G><G><E><G><E><V><T><S><E><A...
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.<BOP>
B7KUT4
Q9V076
RNJ_PYRAB
Pab-RNase J
Pyrococcus
<M><W><E><E><I><N><M><I><K><I><Y><T><L><G><G><Y><E><E><V><G><K><N><M><T><A><V><E><Y><N><G><E><V><V><I><V><D><M><G><I><R><L><D><R><V><L><I><H><E><D><V><E><F><Q><K><M><S><S><K><D><L><R><K><L><G><A><I><P><D><D><R><P><I><R><N><K><K><V><V><A><I><A><L><S><H><G><H><L><D><H><I><G><A><V><G><K><L><A><P><H><Y><P><D><V><P><I><Y><G...
A highly processive 5'-3' exoribonuclease; no evidence has been seen for endonuclease activity. Prefers 5'-phosphate or 5'-hydroxyl ends; 5'-triphosphate substrates are very poorly degraded, does not degrade circular RNA. Does not degrade pre-tRNA(Trp) suggesting it is inhibited by strong secondary structures. Also deg...
Q9V076
O98462
RPOA_SPIMX
Plastid-encoded RNA polymerase subunit alpha
Spirogyra
<M><G><Q><Y><T><I><N><L><R><E><S><Y><P><V><W><K><I><G><S><K><I><D><S><T><K><E><E><C><L><D><Y><M><L><F><I><A><S><P><L><L><A><G><Q><A><T><T><L><G><V><A><I><R><R><T><L><L><E><S><I><Q><G><T><A><I><V><A><A><K><I><Y><G><A><A><H><E><Y><S><T><L><E><G><I><Q><E><S><I><H><D><I><L><L><N><L><K><Q><V><I><I><K><N><K><I><C><E><F><Q><K...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
O98462
A8AHD6
ASTE_CITK8
Succinylglutamate desuccinylase
Citrobacter
<M><D><N><F><L><A><Q><T><L><A><G><I><S><P><D><I><T><Q><G><E><T><E><S><F><H><W><R><W><Q><M><P><G><V><L><E><L><T><P><A><V><E><V><D><R><A><L><V><L><S><A><G><I><H><G><N><E><T><A><P><V><E><M><L><A><A><L><L><S><A><L><F><E><G><K><I><P><L><R><W><R><L><L><V><I><L><G><N><P><P><A><L><A><E><G><V><R><Y><C><H><S><D><M><N><R><M><F><G...
Transforms N(2)-succinylglutamate into succinate and glutamate.<BOP>
A8AHD6
A8FP46
DNAA_SHESH
Chromosomal replication initiator protein DnaA
Shewanella
<M><A><V><S><L><W><Q><Q><C><I><G><R><L><Q><D><E><L><S><A><Q><Q><F><S><M><W><I><R><P><L><Q><A><Q><M><D><G><D><T><L><V><L><Y><A><P><N><R><F><V><L><D><W><V><R><D><K><Y><I><N><I><I><N><Q><F><F><T><E><Q><M><G><S><D><A><P><K><L><R><F><D><I><G><S><R><P><S><A><P><R><P><V><Q><A><T><A><A><V><E><R><P><K><F><E><Q><N><T><K><P><A><K...
Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.<BOP>
A8FP46
P07334
CDR1_SCHPO
Protein kinase nim1
Schizosaccharomyces
<M><V><K><R><H><K><N><T><I><G><V><W><R><L><G><K><T><L><G><T><G><S><T><S><C><V><R><L><A><K><H><A><K><T><G><D><L><A><A><I><K><I><I><P><I><R><Y><A><S><I><G><M><E><I><L><M><M><R><L><L><R><H><P><N><I><L><R><L><Y><D><V><W><T><D><H><Q><H><M><Y><L><A><L><E><Y><V><P><D><G><E><L><F><H><Y><I><R><K><H><G><P><L><S><E><R><E><A><A><H...
This protein, a dose-dependent mitotic inducer, appears to function as a negative regulator of mitosis inhibitor wee1 by phosphorylating and inactivating it.<BOP>
P07334
A6TVQ2
MURQ_ALKMQ
N-acetylmuramic acid 6-phosphate lyase
Alkaliphilus
<M><L><N><N><L><E><Q><L><T><T><E><K><V><N><L><E><T><L><N><I><D><E><K><S><P><L><E><I><V><K><V><I><N><E><E><D><K><K><V><A><L><A><V><E><K><E><L><P><N><I><A><K><A><V><E><K><I><I><E><A><F><K><T><N><G><R><L><I><Y><L><G><A><G><T><S><G><R><L><G><I><L><D><A><A><E><C><P><P><T><F><G><T><S><K><E><Q><V><I><G><L><I><A><G><G><R><E><A...
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.<BOP>
A6TVQ2