accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
Q7NZV7
CYSG_CHRVO
Sirohydrochlorin ferrochelatase
Chromobacterium
<M><E><F><F><P><I><F><L><K><L><R><H><Q><R><C><L><L><V><G><G><G><E><V><A><L><R><K><A><R><L><L><L><A><A><G><A><S><L><Q><V><V><A><P><E><L><A><P><E><L><A><D><L><A><E><R><G><E><L><E><H><L><P><G><R><Y><A><P><A><L><L><D><G><M><R><L><A><V><A><A><T><D><D><A><E><V><N><R><A><V><A><A><D><A><E><A><R><G><I><L><V><N><V><V><D><D><A><E...
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yie...
Q7NZV7
Q8N264
RHG24_HUMAN
p73RhoGAP
Homo
<M><E><E><N><N><D><S><T><E><N><P><Q><Q><G><Q><G><R><Q><N><A><I><K><C><G><W><L><R><K><Q><G><G><F><V><K><T><W><H><T><R><W><F><V><L><K><G><D><Q><L><Y><Y><F><K><D><E><D><E><T><K><P><L><G><T><I><F><L><P><G><N><K><V><S><E><H><P><C><N><E><E><N><P><G><K><F><L><F><E><V><V><P><G><G><D><R><D><R><M><T><A><N><H><E><S><Y><L><L><M><A...
Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and prom...
Q8N264
Q9ZL42
RIBA_HELPJ
GTP cyclohydrolase II
Helicobacter
<M><K><R><L><E><V><S><N><Q><A><K><L><P><T><Q><F><G><E><F><C><I><Q><C><F><R><E><K><G><S><N><G><S><K><D><H><L><V><I><F><T><P><N><F><P><Q><N><P><L><V><R><L><H><S><E><C><L><T><G><D><A><L><G><S><Q><K><C><D><C><G><G><A><L><Q><M><A><L><E><R><I><S><K><E><G><G><L><V><I><Y><L><R><Q><E><G><R><G><I><G><L><F><N><K><V><N><A><Y><A><L...
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.<BOP>
Q9ZL42
Q5E9N2
CNBP1_BOVIN
Beta-catenin-interacting protein 1
Bos
<M><N><R><E><G><A><P><G><K><S><P><E><E><M><Y><I><Q><Q><K><V><R><V><L><L><M><L><R><K><M><G><S><N><L><T><A><N><E><E><E><F><L><R><T><Y><A><G><V><V><N><S><Q><L><S><Q><L><P><Q><H><S><I><D><Q><G><A><E><D><V><V><M><A><F><S><R><S><E><T><E><D><R><R><Q>
Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.<BOP>
Q5E9N2
Q07QP5
CAPP_RHOP5
Phosphoenolpyruvate carboxylase
Rhodopseudomonas
<M><S><S><T><V><L><S><V><E><P><D><A><L><P><R><S><G><E><D><A><A><A><I><A><E><D><A><R><L><R><D><D><I><R><L><L><G><R><I><L><G><D><T><V><R><D><Q><E><G><E><D><V><F><D><A><V><E><R><I><R><Q><T><S><I><R><F><H><R><D><N><D><Q><P><A><R><D><E><L><V><E><L><F><D><G><L><S><T><P><A><T><L><R><I><V><R><A><F><S><Y><F><S><H><L><A><N><L><A...
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.<BOP>
Q07QP5
A1W118
NADD_CAMJJ
Nicotinate mononucleotide adenylyltransferase
Campylobacter
<M><K><I><A><L><F><G><G><S><F><D><P><P><H><N><G><H><N><S><V><V><L><E><A><L><E><K><L><D><I><D><K><L><I><I><M><P><T><Y><I><N><P><F><K><K><S><F><S><A><D><E><K><Q><R><F><L><W><V><K><K><L><W><G><H><L><P><K><V><E><I><C><D><F><E><I><R><Q><K><R><P><V><P><S><I><E><S><V><K><Y><L><Y><K><L><Y><N><P><S><K><F><Y><L><L><I><G><A><D><H...
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).<BOP>
A1W118
Q9M3L4
CEMA_SPIOL
Chloroplast envelope membrane protein
Spinacia
<M><E><K><K><K><V><F><I><P><F><L><Y><L><I><S><I><V><F><L><P><W><W><I><Y><L><S><F><Q><K><S><L><E><S><W><V><T><T><W><W><N><T><K><Q><S><E><T><F><L><N><D><I><Q><E><K><K><L><L><E><K><F><I><E><L><E><E><L><R><L><L><D><E><M><I><K><E><Y><P><E><T><Q><L><Q><K><L><G><I><G><I><H><N><E><T><I><Q><L><I><K><M><H><N><E><D><C><I><H><M><I...
May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake into chloroplasts.<BOP>
Q9M3L4
A4WE57
GCST_ENT38
Glycine cleavage system T protein
Enterobacter
<M><A><Q><Q><T><P><L><Y><E><Q><H><T><L><C><G><A><R><M><V><D><F><H><G><W><M><M><P><L><H><Y><G><S><Q><I><D><E><H><H><A><V><R><T><D><A><G><M><F><D><V><S><H><M><T><I><V><D><L><R><G><S><R><T><R><E><F><L><R><Y><L><L><A><N><D><V><A><K><L><K><T><P><G><K><A><L><Y><S><G><M><L><N><A><S><G><G><V><I><D><D><L><I><V><Y><Y><F><T><E><D...
The glycine cleavage system catalyzes the degradation of glycine.<BOP>
A4WE57
P39773
GPMI_BACSU
Vegetative protein 107
Bacillus
<M><S><K><K><P><A><A><L><I><I><L><D><G><F><G><L><R><N><E><T><V><G><N><A><V><A><L><A><K><K><P><N><F><D><R><Y><W><N><Q><Y><P><H><Q><T><L><T><A><S><G><E><A><V><G><L><P><E><G><Q><M><G><N><S><E><V><G><H><L><N><I><G><A><G><R><I><V><Y><Q><S><L><T><R><V><N><V><A><I><R><E><G><E><F><E><R><N><Q><T><F><L><D><A><I><S><N><A><K><E><N...
Essential for rapid growth and for sporulation. Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.<BOP>
P39773
Q9P6Q2
ENOPH_SCHPO
2,3-diketo-5-methylthio-1-phosphopentane phosphatase
Schizosaccharomyces
<M><V><K><N><L><L><L><D><I><E><G><T><V><G><S><I><S><F><V><K><D><K><L><F><P><Y><A><A><S><R><Y><E><S><Y><V><N><E><N><Y><E><S><D><E><N><L><R><E><L><G><K><T><P><E><E><A><L><I><N><L><R><K><L><H><A><E><G><S><K><E><R><S><F><K><M><V><Q><G><R><I><W><K><K><G><Y><E><S><N><E><L><T><S><H><L><F><P><D><V><V><P><A><I><Q><R><S><L><Q><L...
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).<BOP>
Q9P6Q2
Q5HQ70
POTA_STAEQ
Spermidine/putrescine import ATP-binding protein PotA
Staphylococcus
<M><N><P><L><L><S><F><K><D><V><S><K><G><F><E><D><V><Q><I><L><N><E><I><N><I><D><I><E><P><G><Y><F><Y><T><L><L><G><P><S><G><C><G><K><T><T><I><L><K><L><I><A><G><F><E><Y><P><D><S><G><D><I><I><Y><K><D><K><P><I><G><K><M><P><P><N><K><R><K><V><N><T><V><F><Q><D><Y><A><L><F><P><H><L><N><V><F><D><N><I><A><Y><G><L><K><L><K><K><L><S...
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.<BOP>
Q5HQ70
A7I3S9
GLYA_CAMHC
Serine hydroxymethyltransferase
Campylobacter
<M><S><N><L><E><N><F><D><K><E><I><F><D><L><T><N><K><E><L><Q><R><Q><C><D><Y><L><E><M><I><A><S><E><N><F><T><Y><P><E><V><M><E><V><M><G><S><I><L><T><N><K><Y><A><E><G><Y><P><G><K><R><Y><Y><G><G><C><E><F><V><D><E><I><E><Q><T><A><I><D><R><C><K><K><L><F><G><C><N><F><A><N><V><Q><P><N><S><G><S><Q><A><N><Q><G><V><Y><G><A><F><I><K...
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a...
A7I3S9
Q8RG36
RL31_FUSNN
50S ribosomal protein L31
Fusobacterium
<M><K><K><G><I><H><P><E><F><D><L><V><V><F><E><D><M><A><G><N><Q><F><L><T><R><S><T><K><I><P><K><E><T><T><T><F><E><G><K><E><Y><P><V><I><K><V><A><V><S><S><K><S><H><P><F><Y><T><G><E><Q><R><F><V><D><T><A><G><R><V><D><K><F><N><K><K><F><N><L><G><K><K>
Binds the 23S rRNA.<BOP>
Q8RG36
A8GDR1
IHFA_SERP5
Integration host factor subunit alpha
Serratia
<M><A><L><T><K><A><E><M><S><E><H><L><F><E><K><L><G><L><S><K><R><D><A><K><D><L><V><E><L><F><F><E><E><V><R><R><A><L><E><N><G><E><Q><V><K><L><S><G><F><G><N><F><D><L><R><D><K><N><Q><R><P><G><R><N><P><K><T><G><E><D><I><P><I><T><A><R><R><V><V><T><F><R><P><G><Q><K><L><K><S><R><V><E><N><A><S><P><K><E>
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.<BOP>
A8GDR1
Q9HRT6
RL44E_HALSA
50S ribosomal protein L44e
Halobacterium
<M><E><M><P><R><R><F><N><S><Y><C><P><N><C><D><E><H><H><Q><L><E><A><E><K><V><R><S><G><R><S><S><G><M><K><W><D><A><R><R><T><K><R><A><N><A><S><I><G><N><H><G><R><F><S><K><V><P><V><G><N><K><P><T><N><R><T><D><L><K><Y><R><C><S><E><C><G><N><A><H><L><R><E><G><W><R><A><G><R><L><V><L><Q><E>
Binds to the 23S rRNA.<BOP>
Q9HRT6
A2BWM0
ARGC_PROM5
N-acetyl-glutamate semialdehyde dehydrogenase
Prochlorococcus
<M><N><V><A><I><V><G><A><T><G><Y><G><G><I><Q><S><V><N><L><L><K><D><N><K><N><Y><K><I><S><Y><L><G><G><Y><K><T><S><G><T><K><W><S><D><N><F><P><F><I><K><L><D><S><N><N><L><I><E><K><I><S><I><D><R><I><A><D><K><A><D><V><A><L><L><C><L><P><N><G><I><S><S><T><L><T><R><G><L><L><E><K><G><V><K><V><I><D><L><S><A><D><Y><R><Y><K><S><L><E...
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.<BOP>
A2BWM0
Q2YHJ2
PA2B_TRIBO
Phosphatidylcholine 2-acylhydrolase
Trimeresurus
<M><R><T><L><W><I><M><A><V><L><L><V><G><V><E><G><S><L><L><E><F><G><R><M><I><K><E><E><T><G><K><N><P><L><F><S><Y><I><S><Y><G><C><Y><C><G><W><G><G><Q><G><Q><P><K><D><A><T><D><R><C><C><F><V><H><D><C><C><Y><G><K><L><W><S><C><S><P><K><T><D><I><Y><F><Y><Y><R><K><N><G><A><I><V><C><A><R><G><T><W><C><E><K><Q><I><C><E><C><D><K><A...
Snake venom phospholipase A2 (PLA2) that impairs hemostasis. It weakly inhibits ADP-induced platelet aggregation when tested on platelet rich plasma from human and rabbit blood (15-25% of inhibition at 5-10 ug of enzyme), and dose-dependently inhibits blood coagulation, possibly by inhibiting thrombin activation. Exhib...
Q2YHJ2
Q8EWZ9
LEPA_MALP2
Ribosomal back-translocase LepA
Malacoplasma
<M><D><K><K><Y><I><R><N><F><S><I><V><A><H><I><D><H><G><K><S><T><L><S><D><R><I><I><E><F><T><N><T><L><T><T><R><E><M><K><N><Q><I><L><D><S><M><D><I><E><R><E><R><G><I><T><I><K><L><N><A><V><Q><L><I><Y><H><N><P><K><D><N><Q><D><Y><Y><F><H><L><I><D><T><P><G><H><V><D><F><T><Y><E><V><S><R><S><L><A><A><C><E><G><A><L><L><V><V><D><A...
Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-t...
Q8EWZ9
P85148
ETC50_ENTFC
Bacteriocin E50-52
Enterococcus
<T><T><K><N><Y><G><N><G><V><C><N><S><V><N><W><C><Q><C><G><N><V><W><A><S><C><N><L><A><T><G><C><A><A><W><L><C><K><L><A>
Bacteriocin active against the Gram-negative bacteria C.jejuni, Y.enterocolitica and Y.pseudotuberculosis, and the Gram-positive bacteria S.aureus, S.epidermidis, L.monocytogenes and Listeria spp. When added to the drinking water of chickens, causes a decrease in the levels of C.jejuni and S.enteritidis in the ceca, an...
P85148
Q2NFV9
RL2_METST
50S ribosomal protein L2
Methanosphaera
<M><G><K><R><L><I><I><Q><R><R><G><R><G><T><P><T><Y><R><S><S><S><H><R><F><R><G><K><V><A><Y><R><S><Y><D><K><L><E><R><E><G><S><L><T><G><I><V><I><D><I><I><H><D><P><G><R><S><A><P><V><A><V><V><K><F><D><N><G><E><E><K><L><V><L><A><P><E><S><I><A><I><D><D><E><I><E><C><G><V><S><A><S><I><E><P><G><N><T><L><P><L><S><E><I><P><E><G><T...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
Q2NFV9
Q5FS38
DCUP_GLUOX
Uroporphyrinogen decarboxylase
Gluconobacter
<M><I><S><E><N><A><P><S><S><P><S><S><K><P><L><L><R><A><L><R><G><E><A><V><W><P><P><P><V><W><L><M><R><Q><A><G><R><Y><L><P><E><F><R><A><M><R><D><R><A><D><F><L><T><R><C><M><T><P><D><M><A><T><E><L><T><I><Q><P><I><R><R><Y><G><M><D><G><A><I><L><F><S><D><I><L><I><L><P><W><A><M><G><Q><S><L><E><F><I><D><G><R><G><P><V><L><G><A><I...
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.<BOP>
Q5FS38
O53561
ECH19_MYCTU
Enoyl-CoA hydratase EchA19
Mycobacterium tuberculosis complex
<M><A><T><V><E><S><G><P><D><A><L><V><E><R><R><G><H><T><L><I><V><T><M><N><R><P><A><A><R><N><A><L><S><T><E><M><M><R><I><M><V><Q><A><W><D><R><V><D><N><D><P><D><I><R><C><C><I><L><T><G><A><G><G><Y><F><C><A><G><M><D><L><K><A><A><T><Q><K><P><P><G><D><S><F><K><D><G><S><Y><G><P><S><R><I><D><A><L><L><K><G><R><R><L><T><K><P><L><I...
Degradation of the cholesterol side chain involves 3 multistep beta-oxidation cycles, this may be involved in the second cycle (Probable). Hydrates 3-OCDO-CoA ((22E)-3-oxo-chol-4,22-dien-24-oyl-CoA) to make (22R)-HOCO-CoA (3-oxo-chol-4-ene-(22R)-hydroxy-24-oyl-CoA). Also acts on octenoyl-CoA. Not active on (E)-3-OCDS-C...
O53561
A3N1B2
PURT_ACTP2
Phosphoribosylglycinamide formyltransferase 2
Actinobacillus
<M><T><T><I><G><T><P><L><R><P><N><A><T><K><V><M><M><L><G><S><G><E><L><G><K><E><V><V><I><E><L><Q><R><L><G><V><E><V><I><A><V><D><R><Y><E><N><A><P><A><Q><Q><V><A><H><R><A><Y><T><I><S><M><L><D><G><A><A><L><R><A><L><V><E><K><E><K><P><D><F><I><V><P><E><V><E><A><I><A><T><A><T><L><V><E><L><E><Q><E><G><Y><N><V><V><P><T><A><K><A...
Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.<BOP>
A3N1B2
Q1MH51
RRF_RHIL3
Ribosome-releasing factor
Rhizobium
<M><S><E><G><I><D><I><K><E><L><K><R><R><M><D><G><A><I><S><V><F><K><G><D><I><A><S><L><R><T><G><R><A><S><A><N><I><L><D><P><V><T><V><E><A><Y><G><S><R><M><P><L><N><Q><V><A><N><I><T><V><P><E><P><R><M><L><S><V><S><V><W><D><K><S><M><V><S><A><V><E><R><G><I><R><E><S><N><L><G><L><N><P><I><I><D><G><Q><N><L><R><I><P><L><P><E><L><N...
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.<BOP>
Q1MH51
A8W3G4
RR7_CUSEX
30S ribosomal protein S7, plastid
Cuscuta subgen. Monogynella
<M><S><R><R><G><T><A><E><K><K><T><A><K><Y><D><P><I><Y><R><N><R><L><V><N><M><L><V><N><R><I><L><K><H><G><K><K><S><L><A><Y><Q><I><I><Y><R><A><V><K><K><I><Q><Q><K><T><E><T><N><P><L><S><V><L><R><Q><A><I><R><G><V><T><P><D><I><T><V><K><A><R><R><V><G><G><S><T><H><Q><V><P><V><E><I><G><S><T><Q><G><K><A><L><A><V><R><W><L><L><A><A...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.<BOP>
A8W3G4
C3PHA2
LGT_CORA7
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Corynebacterium
<M><Q><I><Y><Y><L><A><N><I><P><S><P><P><Q><G><V><W><H><L><G><P><V><P><I><R><A><Y><A><M><C><I><I><V><G><I><L><V><A><L><W><M><T><L><R><R><Y><T><A><R><G><G><N><P><D><V><V><W><D><A><A><L><V><V><I><P><A><G><I><I><G><G><R><L><Y><H><V><I><T><D><N><D><K><Y><F><C><S><T><C><D><P><L><D><A><L><K><I><T><N><G><G><L><G><I><W><G><A><V...
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.<BOP>
C3PHA2
Q47G87
NIFW_DECAR
Nitrogenase-stabilizing/protective protein NifW
Dechloromonas
<M><E><D><T><L><S><L><A><E><A><M><E><D><L><V><S><A><E><D><F><L><D><Y><F><A><V><P><Y><D><P><A><V><V><H><V><N><R><L><H><I><L><Q><R><F><H><D><Y><L><A><K><Q><A><P><N><L><P><P><E><E><S><Q><Q><R><G><I><Y><R><L><W><L><E><R><A><Y><Q><D><F><V><T><S><D><S><L><T><E><K><V><F><A><V><F><Q><T><V><S><K><P><D><G><G><M><S><S><F><V><S><L...
May protect the nitrogenase Fe-Mo protein from oxidative damage.<BOP>
Q47G87
Q06GW5
RPOA_DRIGR
Plastid-encoded RNA polymerase subunit alpha
Drimys
<M><V><R><E><E><V><A><V><S><T><R><T><L><Q><W><K><C><V><E><S><R><T><D><S><K><R><L><S><Y><G><R><F><I><L><S><P><L><M><K><G><Q><A><D><M><I><G><I><A><M><R><R><A><L><L><G><E><I><E><G><T><C><I><T><R><A><K><S><D><K><I><P><H><E><Y><S><T><I><V><G><I><E><E><S><V><H><Q><I><L><M><N><L><K><E><I><V><L><R><S><N><L><Y><G><T><C><D><A><S...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
Q06GW5
Q9SGU3
MYB72_ARATH
Myb-related protein 72
Arabidopsis
<M><G><K><G><R><A><P><C><C><D><K><N><K><V><K><R><G><P><W><S><P><Q><E><D><L><T><L><I><T><F><I><Q><K><H><G><H><Q><N><W><R><S><L><P><K><L><A><G><L><L><R><C><G><K><S><C><R><L><R><W><I><N><Y><L><R><P><D><V><K><R><G><N><F><S><K><K><E><E><D><A><I><I><H><Y><H><Q><T><L><G><N><K><W><S><K><I><A><S><F><L><P><G><R><T><D><N><E><I><K...
Involved in metal ions homeostasis, including iron ions (Fe) acquisition, via the regulation of NAS4 and NAS2 genes expression. Necessary for plant survival in alkaline soil where iron availability is greatly restricted . Involved in the up-regulation of several biosynthesis genes of secondary metabolites involved in i...
Q9SGU3
B2J4Q8
CHEB_NOSP7
Protein-glutamate methylesterase/protein-glutamine glutaminase
Nostoc
<M><R><I><A><I><V><N><D><T><A><M><A><V><E><A><L><K><R><V><L><L><T><V><P><G><H><E><I><S><W><I><A><R><D><G><T><E><A><V><A><R><C><A><R><D><T><P><D><L><I><L><M><D><L><F><M><P><V><M><D><G><V><E><A><T><R><Q><I><M><K><Q><S><P><C><A><I><I><I><V><T><A><S><V><S><K><N><A><G><K><V><F><E><A><M><G><Y><G><A><R><D><A><V><N><V><P><I><L...
Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deam...
B2J4Q8
Q89AQ2
MURD_BUCBP
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Buchnera
<M><T><R><N><Y><L><H><K><K><I><L><I><F><G><M><G><L><T><G><I><S><C><L><N><F><F><L><S><K><G><I><Y><P><K><I><M><D><T><D><K><R><P><K><H><I><E><K><I><I><K><F><K><N><I><C><Y><H><T><G><S><V><N><Y><S><W><I><L><Q><S><N><L><I><I><V><S><P><G><I><T><P><S><H><P><A><L><K><F><A><T><K><K><N><I><E><I><I><G><D><I><E><L><F><V><Q><E><T><K...
Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).<BOP>
Q89AQ2
Q604M1
ISPF_METCA
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Methylococcus
<M><F><R><I><G><Q><G><Y><D><A><H><R><F><K><E><G><D><H><I><V><L><C><G><V><K><I><P><F><G><R><G><F><A><A><H><S><D><G><D><V><A><L><H><A><L><C><D><A><L><L><G><A><A><A><L><G><D><I><G><R><H><F><P><D><T><D><A><R><Y><K><G><I><D><S><R><V><L><L><R><E><V><R><Q><R><I><A><S><L><G><Y><T><V><G><N><V><D><V><T><V><V><A><Q><A><P><R><L><A...
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a correspond...
Q604M1
A6VQJ6
LPXA_ACTSZ
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Actinobacillus
<M><I><H><S><T><A><K><I><H><P><S><A><I><V><E><E><G><A><K><I><G><E><N><A><I><I><G><P><F><C><V><V><E><K><D><A><E><I><G><K><G><T><I><L><Y><S><H><V><V><V><R><G><I><T><K><I><G><E><D><N><R><I><Y><Q><G><A><S><I><G><E><I><N><Q><D><L><K><Y><Q><G><E><A><T><R><T><V><I><G><N><R><N><R><I><R><E><N><V><T><I><H><R><G><T><A><Q><G><G><W...
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP>
A6VQJ6
P42077
RPOC1_PROMD
Transcriptase subunit gamma
Prochlorococcus
<E><V><T><K><P><E><T><I><N><Y><R><T><L><K><P><E><M><D><G><L><F><C><E><K><I><F><G><P><S><K><D><W><E><C><H><C><G><K><Y><K><R><V><R><H><R><G><I><V><C><E><R><C><G><V><E><V><T><E><S><R><V><R><R><H><R><M><G><Y><I><K><L><A><A><P><V><S><H><V><W><Y><L><K><G><I><P><S><Y><V><A><I><L><L><D><I><P><L><R><D><V><E><Q><I><V><Y><F><N><C...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
P42077
A9VG56
BIOF_BACMK
8-amino-7-ketopelargonate synthase
Bacillus cereus group
<M><N><Q><M><W><R><T><H><L><Q><S><K><V><E><Q><L><K><E><Q><G><Q><Y><R><N><L><H><V><T><E><K><A><E><E><T><W><L><I><R><N><E><K><R><M><L><N><L><A><S><N><N><Y><L><G><L><A><G><D><E><R><L><K><E><A><A><I><A><C><T><R><K><Y><G><T><G><A><T><A><S><R><L><V><V><G><N><Y><P><L><Y><E><E><V><E><R><S><I><C><D><W><K><G><T><E><R><A><L><I><V...
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.<BOP>
A9VG56
Q9ZPI5
MFP2_ARATH
3-hydroxyacyl-CoA dehydrogenase
Arabidopsis
<M><D><S><R><T><K><G><K><T><V><M><E><V><G><G><D><G><V><A><V><I><T><L><I><N><P><P><V><N><S><L><S><F><D><V><L><Y><N><L><K><S><N><Y><E><E><A><L><S><R><N><D><V><K><A><I><V><I><T><G><A><K><G><R><F><S><G><G><F><D><I><S><G><F><G><E><M><Q><K><G><N><V><K><E><P><K><A><G><Y><I><S><I><D><I><I><T><D><L><L><E><A><A><R><K><P><S><V><A...
Involved in peroxisomal fatty acid beta-oxidation during seed germination. Possesses enoyl-CoA hydratase activity against long chain substrates (C14-C18) and 3-hydroxyacyl-CoA dehydrogenase activity against chains of variable sizes (C6-C18) . Possesses 3-hydroxy-3-phenylpropionyl-CoA dehydrogenase activity and is invol...
Q9ZPI5
B9M5B4
ILVD_GEODF
Dihydroxy-acid dehydratase
Geotalea
<M><R><S><D><M><I><K><K><G><L><E><R><T><P><H><R><A><L><L><K><G><T><G><V><P><Q><S><Q><M><E><K><P><F><I><G><V><A><T><S><F><T><D><L><I><P><G><H><V><G><M><R><D><L><E><R><Y><I><E><K><G><I><H><S><G><G><G><Y><A><F><F><F><G><I><P><G><V><C><D><G><I><S><M><G><H><K><G><M><H><Y><S><L><P><T><R><E><L><I><A><D><M><V><E><S><V><A><E><A...
Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (...
B9M5B4
B1VAM3
RS7_PHYAS
30S ribosomal protein S7
16SrXII (Stolbur group)
<M><S><R><K><G><H><I><K><K><R><D><V><N><P><D><P><I><Y><N><S><K><L><V><T><K><V><I><N><V><I><M><Q><D><G><K><K><G><K><A><Q><T><I><F><Y><Q><A><L><K><K><V><Q><L><M><T><K><R><E><P><L><E><V><F><R><D><A><L><N><N><I><M><P><V><L><E><V><R><T><R><R><V><G><G><Q><N><Y><Q><V><P><S><E><I><R><P><E><R><R><Q><S><L><G><L><K><W><L><V><K><F...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.<BOP>
B1VAM3
B9KFR5
CMOB_CAMLR
tRNA U34 carboxymethyltransferase
Campylobacter
<M><Q><D><N><A><L><L><K><Q><A><L><K><H><P><L><Y><E><K><I><Q><K><L><N><L><K><V><Q><N><S><N><Y><T><I><D><D><S><F><N><I><F><C><D><E><K><L><D><E><E><I><K><N><I><A><L><E><L><K><P><W><R><K><G><P><F><K><I><N><K><L><F><I><D><T><E><W><Q><S><F><I><K><F><N><I><L><K><P><Y><M><Q><E><I><K><G><K><V><V><A><D><I><G><C><N><N><G><Y><Y><M...
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.<BOP>
B9KFR5
B2S684
RS12_BRUA1
30S ribosomal protein S12
Brucella
<M><P><T><V><N><Q><L><I><R><K><P><R><T><A><P><V><K><R><N><K><V><P><A><L><Q><A><N><P><Q><K><R><G><V><C><T><R><V><Y><T><T><T><P><K><K><P><N><S><A><L><R><K><V><A><K><V><R><L><T><N><G><F><E><V><I><G><Y><I><P><G><E><G><H><N><L><Q><E><H><S><V><V><M><I><R><G><G><R><V><K><D><L><P><G><V><R><Y><H><I><I><R><G><V><L><D><T><Q><G><V...
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com...
B2S684
B9DVQ2
Y1611_STRU0
Nucleoid-associated protein SUB1611
Streptococcus
<M><M><N><M><Q><N><M><M><K><Q><A><Q><K><L><Q><K><Q><M><E><Q><K><Q><A><D><L><A><A><M><T><F><V><G><K><S><A><Q><D><L><V><T><A><T><F><T><G><D><K><K><M><V><S><I><D><F><K><E><A><V><V><D><P><D><D><M><E><T><L><S><D><M><T><T><Q><A><I><N><D><A><L><A><Q><I><D><E><A><T><K><K><T><M><G><A><F><A><G><K><L><P><F>
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP>
B9DVQ2
Q6PQZ1
AQP1_PIG
Water channel protein for red blood cells and kidney proximal tubule
Sus
<M><A><S><E><F><K><K><K><I><F><W><R><A><V><V><A><E><F><L><A><M><T><L><F><I><F><I><S><I><G><S><A><L><G><F><Q><Y><P><V><R><N><N><Q><T><S><G><A><A><Q><D><N><V><K><V><S><L><A><F><G><L><S><I><A><T><L><A><Q><S><V><G><H><I><S><G><A><H><L><N><P><A><V><T><L><G><L><L><L><S><C><Q><I><S><V><L><R><A><V><M><Y><I><I><A><Q><C><V><G><A...
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.<BOP>
Q6PQZ1
Q8HVV8
NDHI_AMBTR
NADH-plastoquinone oxidoreductase subunit I
Ambrosia
<M><F><P><M><V><T><E><F><M><N><Y><G><Q><Q><T><V><R><A><A><R><Y><I><G><Q><G><F><M><I><T><L><S><H><A><N><R><L><P><V><T><I><Q><Y><P><Y><E><K><L><I><T><S><E><R><F><R><G><R><I><H><F><E><F><D><K><C><I><A><C><E><V><C><V><R><V><C><P><I><D><L><P><V><V><D><W><K><L><E><T><D><I><R><K><K><R><L><L><N><Y><S><I><D><F><G><I><C><I><F><C...
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translo...
Q8HVV8
Q6L1F5
DTDA_PICTO
D-tyrosyl-tRNA(Tyr) deacylase
Picrophilus
<M><D><L><I><I><A><S><R><M><D><E><A><S><M><L><M><A><E><K><I><I><D><L><Y><D><F><N><R><L><N><E><N><E><Y><Q><K><D><G><F><K><L><M><F><I><D><D><L><H><I><Y><H><N><M><E><K><L><D><F><D><T><L><I><F><L><S><R><H><S><S><S><A><G><V><K><S><L><T><V><H><S><I><G><N><Y><R><K><A><E><L><G><G><Y><D><N><K><T><V><L><S><A><P><Y><E><M><S><S><S...
D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.<BOP>
Q6L1F5
A6QR20
SLF1_BOVIN
BRCT domain-containing protein 1
Bos
<M><E><D><D><A><P><K><H><I><I><Q><M><T><G><F><K><V><E><E><K><E><A><L><G><K><L><L><L><K><L><D><C><T><F><I><K><S><E><K><Y><K><N><C><T><H><L><I><A><E><R><L><C><K><S><E><K><F><L><A><A><C><A><A><G><K><W><V><L><T><K><D><Y><I><I><H><S><A><Q><S><G><R><W><L><D><E><T><T><Y><E><W><G><Y><K><I><E><K><D><S><H><Y><S><P><Q><M><Q><S><A...
Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance. The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin ...
A6QR20
Q6D7I5
KDPC_PECAS
Potassium-translocating ATPase C chain
Pectobacterium
<M><R><Y><L><R><S><S><L><F><L><F><L><L><L><L><L><V><T><G><L><A><Y><P><L><L><T><T><V><L><A><Q><W><L><F><P><T><Q><A><N><G><S><L><I><Y><R><D><N><A><V><V><G><S><S><L><I><G><Q><S><F><S><R><T><G><Y><F><Q><G><R><P><S><A><T><S><D><A><P><Y><N><A><L><A><S><G><G><S><N><L><A><A><S><N><P><A><L><D><K><Q><I><G><E><R><A><A><Y><W><H><Q...
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation...
Q6D7I5
D3UAG5
88F1R_MALDO
UDP-glycosyltransferase 88F1
Malus
<M><G><D><V><I><V><L><Y><A><S><P><G><M><G><H><I><V><S><M><V><E><L><G><K><F><I><V><H><R><Y><G><P><H><K><F><S><I><T><I><L><Y><T><C><G><S><I><V><D><T><A><S><I><P><V><Y><I><R><R><I><S><H><S><H><P><F><I><S><F><R><Q><F><P><R><V><T><N><N><I><T><R><N><I><S><V><P><A><I><T><F><D><F><I><R><Q><N><D><P><H><V><R><S><A><L><Q><E><I><S...
Glycosyltransferase that possesses phloretin 2'-O-glycosyltransferase activity. Converts phloretin to phlorizin (phloretin 2'-O-glucoside), a potent antioxidant. Is specific for phloretin and does not possess glycosyltransferase activity toward caffeic acid, catechin, chlorogenic acid, 2-coumaric acid, 3-coumaric acid,...
D3UAG5
Q8LG10
GAT15_ARATH
GATA transcription factor 15
Arabidopsis
<M><L><D><P><T><E><K><V><I><D><S><E><S><M><E><S><K><L><T><S><V><D><A><I><E><E><H><S><S><S><S><S><N><E><A><I><S><N><E><K><K><S><C><A><I><C><G><T><S><K><T><P><L><W><R><G><G><P><A><G><P><K><S><L><C><N><A><C><G><I><R><N><R><K><K><R><R><T><L><I><S><N><R><S><E><D><K><K><K><K><S><H><N><R><N><P><K><F><G><D><S><L><K><Q><R><L><M...
Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters.<BOP>
Q8LG10
Q80ZG1
RIC8A_RAT
Protein Ric-8A
Rattus
<M><E><P><R><A><V><A><D><A><L><E><T><G><E><E><D><A><V><T><E><A><L><R><S><F><N><R><E><H><S><Q><S><F><T><F><D><D><A><Q><Q><E><D><R><K><R><L><A><K><L><L><V><S><V><L><E><Q><G><L><S><P><K><H><R><V><T><W><L><Q><T><I><R><I><L><S><R><D><R><S><C><L><D><S><F><A><S><R><Q><S><L><H><A><L><A><C><Y><A><D><I><A><I><S><E><E><P><I><P><Q...
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, poss...
Q80ZG1
A5UCY6
ENGB_HAEIE
Probable GTP-binding protein EngB
Haemophilus
<M><S><E><I><K><L><N><Y><H><K><T><H><F><L><T><S><A><P><N><I><R><S><I><P><E><D><T><G><I><E><I><A><F><A><G><R><S><N><A><G><K><S><T><A><L><N><A><L><T><N><Q><K><N><L><A><R><T><S><K><T><P><G><R><T><Q><L><I><N><L><F><E><V><E><P><N><Y><K><L><V><D><L><P><G><Y><G><Y><A><A><V><P><E><Q><M><K><I><Q><W><Q><K><S><L><G><E><Y><L><Q><K...
Necessary for normal cell division and for the maintenance of normal septation.<BOP>
A5UCY6
Q6D163
GLNE_PECAS
Adenylyl transferase
Pectobacterium
<M><S><I><L><P><L><P><A><L><P><V><L><L><T><E><Q><S><Q><R><A><L><S><R><L><R><E><A><A><P><D><E><P><I><T><D><S><D><S><A><V><L><A><L><S><D><F><V><S><D><A><L><A><L><H><P><D><W><W><Q><G><I><H><Q><Q><P><P><Q><P><E><E><W><Q><H><Y><A><D><W><L><S><N><A><L><V><D><V><N><D><E><N><A><L><M><A><A><L><R><R><F><R><R><H><M><L><A><R><I><A...
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activit...
Q6D163
P10620
MGST1_HUMAN
Microsomal GST-I
Homo
<M><V><D><L><T><Q><V><M><D><D><E><V><F><M><A><F><A><S><Y><A><T><I><I><L><S><K><M><M><L><M><S><T><A><T><A><F><Y><R><L><T><R><K><V><F><A><N><P><E><D><C><V><A><F><G><K><G><E><N><A><K><K><Y><L><R><T><D><D><R><V><E><R><V><R><R><A><H><L><N><D><L><E><N><I><I><P><F><L><G><I><G><L><L><Y><S><L><S><G><P><D><P><S><T><A><I><L><H><F...
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a wide substrate specificity.<BOP>
P10620
Q1LSL0
TRUB_BAUCH
tRNA-uridine isomerase
Candidatus Baumannia
<M><C><F><S><L><N><I><N><S><H><N><I><N><G><I><I><L><L><D><K><Q><E><G><L><S><S><N><Y><L><L><H><K><V><K><R><L><F><R><V><Q><K><A><G><H><T><G><A><L><D><P><L><A><S><G><M><L><P><I><C><L><G><E><A><T><K><F><S><K><Y><L><L><D><A><D><K><R><Y><I><V><S><A><K><L><G><E><K><T><N><T><Y><D><A><T><G><I><I><I><N><T><R><P><V><T><I><N><Q><A...
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP>
Q1LSL0
Q2RVG7
EFP_RHORT
Elongation factor P
Rhodospirillum
<M><K><M><Q><A><N><Q><I><R><P><G><Q><V><L><E><H><Q><G><K><R><W><T><V><L><K><I><Q><L><I><Q><P><G><K><G><G><A><F><I><A><V><E><M><R><D><V><D><S><G><N><K><T><N><E><R><W><R><T><A><D><T><V><E><R><L><E><V><R><E><I><D><C><Q><Y><L><F><K><D><D><T><G><Y><T><F><M><D><K><E><T><F><E><Q><F><S><M><A><A><D><A><L><G><E><Q><A><G><F><L><Q...
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP>
Q2RVG7
B5EXA8
LLDD_SALA4
L-lactate dehydrogenase
Salmonella
<M><I><I><S><A><A><S><D><Y><R><A><A><A><Q><R><T><L><P><P><F><L><F><H><Y><I><D><G><G><A><Y><A><E><Y><T><L><R><R><N><V><E><D><L><S><Q><V><A><L><R><Q><R><V><L><K><N><M><S><D><L><S><L><E><T><T><L><F><N><E><T><L><S><M><P><V><A><L><A><P><V><G><L><C><G><M><Y><A><R><R><G><E><V><Q><A><A><A><A><A><D><A><K><G><I><P><F><T><L><S><T...
Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.<BOP>
B5EXA8
Q3K6Y7
HEMH_PSEPF
Protoheme ferro-lyase
Pseudomonas
<M><T><D><H><A><L><L><L><V><N><L><G><S><P><A><S><T><S><V><A><D><V><R><R><Y><L><N><Q><F><L><M><D><P><Y><V><I><D><L><P><W><P><V><R><R><L><L><V><S><L><I><L><I><K><R><P><E><Q><S><A><H><A><Y><A><S><I><W><W><D><E><G><S><P><L><V><V><L><S><R><R><L><Q><Q><Q><M><K><A><Q><W><T><H><G><P><V><E><L><A><M><R><Y><G><E><P><S><I><E><T><N...
Catalyzes the ferrous insertion into protoporphyrin IX.<BOP>
Q3K6Y7
B0KC91
PANC_THEP3
Pantoate-activating enzyme
Thermoanaerobacter
<M><I><V><T><D><K><I><S><N><V><R><N><I><I><K><E><Q><K><L><S><G><K><K><I><G><L><V><P><T><M><G><Y><L><H><E><G><H><L><S><L><V><R><I><A><K><K><H><S><D><F><V><A><V><S><I><F><V><N><P><I><Q><F><G><P><N><E><D><F><D><R><Y><P><R><D><L><E><R><D><L><K><L><L><E><K><E><G><C><D><L><V><F><A><P><S><V><E><E><M><Y><P><S><E><L><L><T><T><V...
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<BOP>
B0KC91
Q46LU1
GLGA_PROMT
Starch [bacterial glycogen] synthase
Prochlorococcus
<M><R><I><L><F><A><A><A><E><C><A><P><M><I><K><V><G><G><M><G><D><V><V><G><S><L><P><P><A><L><K><K><L><G><H><D><V><R><L><I><I><P><G><Y><G><K><L><W><T><L><M><D><I><A><P><E><P><I><F><R><S><N><T><M><G><V><D><F><S><V><F><E><T><K><H><P><S><N><G><L><P><I><Y><L><V><G><H><P><C><F><D><S><E><R><I><Y><G><G><E><D><E><D><W><R><F><T><F...
Synthesizes alpha-1,4-glucan chains using ADP-glucose.<BOP>
Q46LU1
Q5LIJ3
MURE_BACFN
UDP-N-acetylmuramyl-tripeptide synthetase
Bacteroides
<M><K><L><K><E><I><L><T><S><I><Q><P><V><K><I><T><G><N><Q><D><I><E><I><T><G><V><D><I><D><S><R><Q><V><E><S><G><H><L><F><M><A><M><H><G><T><Q><T><D><G><H><A><Y><I><P><A><A><V><E><K><G><A><T><A><I><L><C><E><E><L><P><A><E><L><A><E><G><V><T><Y><I><Q><V><A><D><S><E><D><A><V><G><K><A><A><T><T><F><Y><G><N><P><S><S><K><L><E><L><V...
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.<BOP>
Q5LIJ3
Q5HAA6
COXX_EHRRW
Heme O synthase
Ehrlichia
<M><G><I><Q><S><S><T><M><K><L><P><L><I><H><E><I><S><D><Y><W><H><L><L><K><P><K><I><M><Y><L><V><V><L><T><G><V><T><G><I><I><I><A><P><G><N><I><H><P><L><I><A><V><I><S><T><L><C><I><A><L><G><S><G><A><A><G><A><I><N><M><W><Y><D><S><D><I><D><A><L><M><T><R><T><K><T><R><P><I><P><A><G><K><I><S><R><S><S><A><L><E><V><G><L><V><L><S><F...
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.<BOP>
Q5HAA6
Q7SY06
HACD3_DANRE
Protein-tyrosine phosphatase-like A domain-containing protein 1
Danio
<M><S><A><L><T><P><H><V><Y><W><A><Q><R><H><G><E><I><Y><L><R><V><E><I><S><D><A><Q><D><L><S><I><G><V><E><E><N><I><L><Q><F><R><G><Q><G><H><G><A><K><G><E><N><E><Y><E><F><S><L><E><F><L><K><P><V><K><P><E><V><K><H><K><S><T><Q><R><Q><V><N><I><T><V><R><K><Q><E><E><V><W><W><N><R><L><T><K><Q><E><K><K><P><L><F><L><A><P><D><F><D><R...
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermed...
Q7SY06
Q2S3F9
RUVB_SALRD
Holliday junction ATP-dependent DNA helicase RuvB
Salinibacter
<M><S><T><S><R><S><D><A><L><K><A><E><A><D><R><S><D><N><D><V><E><K><L><L><R><P><Q><S><L><D><E><F><V><G><Q><E><K><I><K><E><N><L><N><V><F><M><K><A><A><L><Q><R><G><E><T><L><D><H><V><L><L><S><G><P><P><G><L><G><K><T><T><L><A><H><I><I><A><N><E><M><G><A><R><I><R><T><S><S><G><P><V><L><E><K><P><A><D><I><A><G><V><L><T><N><L><E><E...
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.<BOP>
Q2S3F9
Q6YXH5
ZHD1_ORYSJ
null
Oryza sativa
<M><D><F><D><D><H><D><D><G><D><E><E><M><P><P><M><P><V><S><S><S><Y><E><T><P><P><Q><H><G><L><A><G><G><G><M><A><P><K><P><P><G><E><I><G><S><R><V><K><G><P><S><C><G><G><G><R><Y><R><E><C><L><K><N><H><A><V><G><I><G><G><H><A><V><D><G><C><G><E><F><M><A><A><G><E><E><G><T><I><D><A><L><R><C><A><A><C><N><C><H><R><N><F><H><R><K><E><S...
Putative transcription factor.<BOP>
Q6YXH5
P80916
ACP_ACICA
Acyl carrier protein
Acinetobacter calcoaceticus/baumannii complex
<M><S><D><I><E><Q><R><I><K><Q><A><V><A><E><Q><L><G><M><R><A><E><E><I><K><N><E>
Carrier of the growing fatty acid chain in fatty acid biosynthesis.<BOP>
P80916
A0ZZZ0
OBG_BIFAA
GTP-binding protein Obg
Bifidobacterium
<M><S><D><F><V><D><R><V><T><V><H><V><K><G><G><D><G><G><N><G><S><A><G><I><R><R><E><K><Y><K><P><L><A><G><P><N><G><G><N><G><G><D><G><G><S><V><I><F><M><A><D><S><N><A><N><S><L><L><D><Y><R><F><M><P><H><R><E><A><E><S><G><T><M><G><L><G><D><T><K><D><G><S><K><G><A><D><L><I><L><P><V><P><V><G><T><V><V><F><E><A><K><G><P><Q><G><K><P...
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B...
A0ZZZ0
Q85FX7
PETN_CYAM1
Cytochrome b6-f complex subunit VIII
Cyanidioschyzon
<M><H><L><D><L><I><S><I><T><W><G><C><L><M><A><T><F><T><A><S><L><A><L><V><I><W><A><R><N><G><L>
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.<BOP>
Q85FX7
A0JN80
DI3L1_BOVIN
DIS3-like exonuclease 1
Bos
<M><L><Q><K><R><E><K><V><L><L><L><R><T><F><H><G><R><T><L><R><I><V><R><E><H><Y><L><R><P><S><V><P><C><N><S><P><L><C><P><Q><P><A><T><C><H><N><D><G><K><L><L><S><S><D><V><T><H><Y><M><V><P><D><W><K><V><V><Q><D><Y><L><E><I><L><E><F><P><E><L><K><G><I><V><F><M><Q><T><A><C><Q><A><V><Q><H><Q><R><G><R><R><Q><Y><N><K><L><R><N><L><L...
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unst...
A0JN80
Q8RXG3
M2K5_ARATH
Mitogen-activated protein kinase kinase 5
Arabidopsis
<M><K><P><I><Q><S><P><S><G><V><A><S><P><M><K><N><R><L><R><K><R><P><D><L><S><L><P><L><P><H><R><D><V><A><L><A><V><P><L><P><L><P><P><P><S><S><S><S><S><A><P><A><S><S><S><A><I><S><T><N><I><S><A><A><K><S><L><S><E><L><E><R><V><N><R><I><G><S><G><A><G><G><T><V><Y><K><V><I><H><T><P><T><S><R><P><F><A><L><K><V><I><Y><G><N><H><E><D...
Mitogen-activated protein kinase kinase (MAPKK) which regulates abscisic acid (ABA) responses in a MAPKKK20-MKK5-MPK6 cascade involved in root growth (e.g. root cell division and elongation) and stomatal response, probably via MAPK6 activation by protein phosphorylation . Involved in the second phase of hydrogen peroxi...
Q8RXG3
Q48V07
NRDI_STRPM
Protein NrdI
Streptococcus
<M><A><E><L><I><I><V><Y><F><S><S><K><S><N><N><T><H><R><F><V><Q><K><L><G><L><P><A><Q><R><I><P><V><D><N><R><P><L><E><V><S><T><H><Y><L><L><I><V><P><T><Y><A><A><G><G><S><D><A><K><G><A><V><P><K><Q><V><I><R><F><L><N><N><P><N><N><R><K><H><C><K><G><V><I><S><S><G><N><T><N><F><G><D><T><F><A><L><A><G><P><I><I><S><Q><K><L><Q><V><P...
Probably involved in ribonucleotide reductase function.<BOP>
Q48V07
Q2FZ95
FTSL_STAA8
Cell division protein FtsL
Staphylococcus
<M><A><V><E><K><V><Y><Q><P><Y><D><E><Q><V><Y><N><S><I><P><K><Q><Q><P><Q><T><K><P><E><K><K><T><V><S><R><K><V><V><V><Q><L><T><K><F><E><K><V><L><Y><I><T><L><I><T><V><I><A><M><L><S><I><Y><M><L><S><L><K><M><D><A><Y><D><T><R><G><K><I><A><D><L><D><Y><K><I><D><K><Q><S><S><E><N><S><A><L><Q><S><E><I><K><K><N><S><S><Y><E><R><I><Y...
Essential cell division protein.<BOP>
Q2FZ95
Q728G0
HTPG_DESVH
High temperature protein G
Desulfovibrio
<M><A><T><A><P><A><S><H><A><F><R><T><E><V><R><K><M><L><H><I><I><T><H><S><L><Y><T><N><R><E><I><F><L><R><E><L><V><S><N><A><S><D><A><L><D><K><L><R><F><I><R><S><R><G><D><A><V><V><A><P><D><L><A><P><G><I><D><I><S><V><D><K><E><A><R><I><L><T><I><A><D><T><G><V><G><M><T><R><Q><E><L><M><D><N><L><G><T><I><A><R><S><G><S><E><Q><F><V...
Molecular chaperone. Has ATPase activity.<BOP>
Q728G0
A5CS07
RUVA_CLAM3
Holliday junction ATP-dependent DNA helicase RuvA
Clavibacter
<M><I><S><S><L><R><G><T><V><L><S><V><S><G><Q><T><L><L><L><E><V><H><G><V><G><Y><G><V><S><V><T><P><R><H><A><L><E><L><R><N><G><S><E><A><T><V><L><T><S><L><V><V><R><E><D><S><L><T><L><F><G><F><P><G><P><D><E><L><R><A><F><E><L><L><C><G><V><T><G><V><G><P><K><S><A><L><A><V><L><E><H><L><D><P><E><A><M><A><Q><A><V><A><A><E><D><D><A...
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA...
A5CS07
C1BYA3
MTNB_ESOLU
APAF1-interacting protein homolog
Esox
<M><V><S><S><Q><E><K><M><A><S><I><S><D><I><I><Q><K><D><E><D><S><G><S><E><K><T><E><S><Q><D><K><E><H><P><R><V><L><I><P><E><L><C><R><L><F><Y><K><L><G><W><V><T><G><T><G><G><G><I><S><L><R><H><G><D><Q><I><Y><I><A><P><S><G><V><Q><K><E><R><L><Q><P><E><D><M><F><V><C><D><V><E><E><R><D><I><C><V><P><P><A><W><K><N><L><K><K><G><Q><C...
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.<BOP>
C1BYA3
P0AGE3
SSB_SHIFL
Single-stranded DNA-binding protein
Shigella
<M><A><S><R><G><V><N><K><V><I><L><V><G><N><L><G><Q><D><P><E><V><R><Y><M><P><N><G><G><A><V><A><N><I><T><L><A><T><S><E><S><W><R><D><K><A><T><G><E><M><K><E><Q><T><E><W><H><R><V><V><L><F><G><K><L><A><E><V><A><S><E><Y><L><R><K><G><S><Q><V><Y><I><E><G><Q><L><R><T><R><K><W><T><D><Q><S><G><Q><D><R><Y><T><T><E><V><V><V><N><V><G...
Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.<BOP>
P0AGE3
Q7RVM2
ARF_NEUCR
ADP-ribosylation factor
Neurospora
<M><G><N><T><L><S><I><F><G><K><L><F><D><G><L><F><G><K><K><E><M><R><I><L><M><V><G><L><D><A><A><G><K><T><T><I><L><Y><K><L><K><L><G><E><V><V><T><T><I><P><T><I><G><F><N><V><E><T><V><E><Y><K><N><I><Q><F><T><V><W><D><V><G><G><Q><D><K><I><R><P><L><W><R><H><Y><F><Q><N><T><Q><G><I><I><F><V><V><D><S><N><D><R><D><R><V><V><E><A><R...
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.<BOP>
Q7RVM2
P49208
RK1_PEA
CL1
Pisum
<I><P><L><F><L><H><L><L><L><M><S><R><K><L><L><M><K><R><R><T><K><V><V><R><R><M><N><L><M><L><L><L><T><L><L><L><S><P><L><S><L><R><Q><G><K><L><H><W><R><L><K><S><D><R><V><R><S><K><R><F><L><E><I><Q><K><L><R><E><L><K><K><E><Y><D><L><K><T><A><I><S><L><V><K><E><T><A><K><T><K><F><V><E><T><V><E><A><H><F><R><L><N><I><D><P><K><Y><N...
This protein binds directly to 23S ribosomal RNA.<BOP>
P49208
Q46ZI7
DER_CUPPJ
GTP-binding protein EngA
Cupriavidus
<M><K><P><V><I><A><L><V><G><R><P><N><V><G><K><S><T><L><F><N><R><M><T><R><S><R><D><A><L><V><A><D><L><P><G><L><T><R><D><R><H><Y><G><E><G><R><I><G><D><R><P><F><I><A><I><D><T><G><G><F><E><P><V><V><K><E><G><I><V><A><E><M><A><K><Q><T><R><Q><A><V><V><E><A><D><V><V><I><F><I><V><D><G><R><L><G><L><A><P><Q><D><R><A><I><A><D><Y><L...
GTPase that plays an essential role in the late steps of ribosome biogenesis.<BOP>
Q46ZI7
Q09147
FGFR2_DROME
dFGF-R1
Sophophora
<M><A><K><V><P><I><T><L><V><M><I><I><A><I><V><S><A><A><A><D><L><G><C><D><Y><G><H><H><R><C><Y><I><D><V><T><V><E><N><S><P><R><Q><R><H><L><L><S><D><M><D><I><T><L><Q><C><V><R><P><M><A><K><W><F><Y><E><D><K><F><Q><L><R><A><T><L><L><R><L><E><R><A><Q><S><G><N><S><G><N><Y><G><C><L><D><S><Q><N><R><W><Y><N><I><S><L><V><V><G><H><K...
May be required for patterning of muscle precursor cells: generation of mesodermal and endodermal layers, invaginations of various types of cells, and CNS formation. Essential for the ability of the migrating tracheal and midline cells to recognize external guiding cues.<BOP>
Q09147
A0A0G2K6Z9
ODAPH_RAT
Odontogenesis-associated phosphoprotein
Rattus
<M><A><P><G><F><H><F><S><W><L><L><V><S><W><L><V><V><T><T><V><K><G><Q><D><V><M><T><P><P><G><S><Q><N><N><V><N><P><T><D><C><Q><I><I><T><L><T><P><P><P><T><T><R><N><Q><L><T><R><A><Q><P><V><T><R><T><P><T><F><Y><F><P><P><R><R><P><G><F><Y><P><R><F><P><N><I><P><F><F><P><P><N><N><R><R><F><Q><L><W><P><F><Y><P><P><R><G><R><L><I><P...
May promote nucleation of hydroxyapatite.<BOP>
A0A0G2K6Z9
P43619
NADC_YEAST
Quinolinate phosphoribosyltransferase [decarboxylating]
Saccharomyces
<M><P><V><Y><E><H><L><L><P><V><N><G><A><W><R><Q><D><V><T><N><W><L><S><E><D><V><P><S><F><D><F><G><G><Y><V><V><G><S><D><L><K><E><A><N><L><Y><C><K><Q><D><G><M><L><C><G><V><P><F><A><Q><E><V><F><N><Q><C><E><L><Q><V><E><W><L><F><K><E><G><S><F><L><E><P><S><K><N><D><S><G><K><I><V><V><A><K><I><T><G><P><A><K><N><I><L><L><A><E><R...
Involved in the catabolism of quinolinic acid (QA).<BOP>
P43619
Q9ZMQ6
ALF_HELPJ
Fructose-1,6-bisphosphate aldolase
Helicobacter
<M><L><V><K><G><N><E><I><L><L><K><A><H><K><E><G><Y><G><V><G><A><F><N><F><V><N><F><E><M><L><N><A><I><F><E><A><G><N><E><E><N><S><P><L><F><I><Q><A><S><E><G><A><I><K><Y><M><G><I><D><M><A><V><G><M><V><K><I><M><C><E><R><Y><P><H><I><P><V><A><L><H><L><D><H><G><T><T><F><E><S><C><E><K><A><V><K><A><G><F><T><S><V><M><I><D><A><S><H...
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.<BOP>
Q9ZMQ6
A1RVE1
AROB_PYRIL
3-dehydroquinate synthase
Pyrobaculum
<M><R><R><F><F><Y><R><H><T><R><G><V><T><E><V><V><V><G><R><G><L><P><Y><G><E><Y><I><E><R><P><V><V><L><A><E><E><G><L><R><P><P><I><P><G><A><P><T><L><V><L><R><G><G><E><E><V><K><S><L><E><V><L><T><K><V><Y><S><F><L><K><E><V><G><A><D><R><S><T><T><L><V><A><V><G><G><G><A><L><L><D><L><A><T><F><A><A><G><T><Y><M><R><G><I><R><L><V><H...
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).<BOP>
A1RVE1
Q8EER2
LOLA_SHEON
Outer-membrane lipoprotein carrier protein
Shewanella
<M><K><K><L><L><C><A><V><L><L><S><P><L><L><Y><S><N><A><V><L><A><D><D><A><K><Q><L><R><E><T><L><T><G><T><E><S><L><K><A><D><F><K><Q><T><V><T><D><V><N><K><K><V><I><Q><S><G><A><G><V><F><A><L><A><H><P><N><Q><F><Y><W><H><L><T><A><P><D><E><S><K><I><V><A><D><G><K><D><L><W><I><Y><N><P><F><A><E><E><V><V><I><M><D><F><T><Q><A><I><T...
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).<BOP>
Q8EER2
Q2S2H7
PLSY_SALRD
Lysophosphatidic acid synthase
Salinibacter
<M><W><S><L><T><V><I><L><L><I><S><Y><F><L><G><S><I><P><G><A><L><W><S><S><K><A><L><H><G><V><D><I><R><N><H><G><S><H><N><C><G><A><T><N><A><F><R><V><V><G><W><Q><A><G><A><L><A><T><V><V><D><F><G><K><G><F><L><A><A><G><V><V><A><S><V><I><R><I><D><P><I><P><S><G><L><S><L><F><G><G><D><P><F><V><V><L><G><L><L><A><G><V><G><A><V><I><G...
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.<BOP>
Q2S2H7
B2VL52
SECB_ERWT9
Protein-export protein SecB
Erwinia
<M><S><E><Q><N><N><T><E><M><S><F><Q><I><Q><R><I><Y><T><K><D><I><S><F><E><A><P><N><A><P><Q><V><F><Q><K><E><W><E><P><E><V><K><L><D><L><D><T><A><S><S><Q><L><A><D><D><V><Y><E><V><V><L><R><V><T><V><T><A><T><V><G><E><D><S><A><F><L><C><E><V><Q><Q><A><G><I><F><S><V><G><G><I><D><G><T><Q><M><A><H><C><L><G><A><Y><C><P><N><I><L><F...
One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.<BOP>
B2VL52
P9WG96
TATC_MYCTO
Sec-independent protein translocase protein TatC
Mycobacterium tuberculosis complex
<M><R><A><A><G><L><L><K><R><L><N><P><R><N><R><R><S><R><V><N><P><D><A><T><M><S><L><V><D><H><L><T><E><L><R><T><R><L><L><I><S><L><A><A><I><L><V><T><T><I><F><G><F><V><W><Y><S><H><S><I><F><G><L><D><S><L><G><E><W><L><R><H><P><Y><C><A><L><P><Q><S><A><R><A><D><I><S><A><D><G><E><C><R><L><L><A><T><A><P><F><D><Q><F><M><L><R><L><K...
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.<BOP>
P9WG96
B4T2Q0
FRDC_SALNS
Quinol-fumarate reductase subunit C
Salmonella
<M><T><T><K><R><K><P><Y><V><R><P><M><T><S><T><W><W><K><K><L><P><F><Y><R><F><Y><M><L><R><E><G><T><A><V><P><A><V><W><F><S><I><E><L><I><F><G><L><F><A><L><K><H><G><A><E><S><W><M><G><F><V><G><F><L><Q><N><P><V><V><V><I><L><N><L><I><T><L><A><A><A><L><L><H><T><K><T><W><F><E><L><A><P><K><A><A><N><I><I><V><K><D><E><K><M><G><P><E...
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth. Anchors the catalytic components of the fumarate reductase complex to the cell inner me...
B4T2Q0
A3CVD3
ECFA_METMJ
Energy-coupling factor transporter ATP-binding protein EcfA
Methanoculleus
<M><H><L><L><E><T><R><D><L><T><H><I><Y><R><G><D><V><H><A><L><E><G><V><N><F><T><A><E><R><K><S><R><I><A><V><I><G><P><N><G><A><G><K><S><T><L><F><K><H><F><N><G><I><L><K><P><T><S><G><E><V><L><V><R><G><E><P><I><T><K><E><N><V><R><E><V><R><K><F><V><G><I><V><F><Q><N><P><D><D><Q><I><F><S><P><T><V><E><Q><D><I><A><F><G><P><I><N><L...
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.<BOP>
A3CVD3
A8FYS8
RLME_SHESH
rRNA (uridine-2'-O-)-methyltransferase
Shewanella
<M><S><G><K><K><R><T><A><S><S><S><R><W><M><Q><E><H><F><D><D><H><Y><V><K><L><A><Q><K><R><G><F><R><S><R><A><A><F><K><I><E><E><I><Q><E><K><D><K><L><I><R><P><G><M><T><V><V><D><L><G><A><A><P><G><G><W><S><Q><V><A><V><K><L><A><G><D><N><G><K><V><I><A><C><D><I><L><P><M><D><P><I><V><G><V><D><F><L><Q><G><D><F><R><E><E><K><V><L><D...
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.<BOP>
A8FYS8
Q07YF5
KATG2_SHEFN
Peroxidase/catalase 2
Shewanella
<M><K><H><P><L><F><N><Q><K><V><L><A><G><F><V><S><M><L><L><I><S><G><S><A><F><A><S><N><N><E><K><S><E><M><T><K><P><K><G><A><V><G><T><G><V><A><L><E><N><Q><A><R><T><N><Q><F><W><W><P><D><Q><L><N><L><S><A><L><R><D><H><D><K><R><S><N><P><Y><G><E><N><F><D><Y><A><K><A><F><N><S><L><D><L><D><K><V><K><L><D><I><N><A><L><L><T><T><S><Q...
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.<BOP>
Q07YF5
A5ELM3
RS19_BRASB
30S ribosomal protein S19
unclassified Bradyrhizobium
<M><V><R><S><V><W><K><G><P><F><V><E><A><S><L><L><K><K><A><D><A><A><R><A><S><G><R><H><D><V><I><K><I><W><S><R><R><S><T><I><L><P><Q><F><V><G><L><T><F><G><V><Y><N><G><Q><K><H><V><P><V><A><V><N><E><E><M><V><G><H><K><F><G><E><F><S><P><T><R><T><F><H><G><H><S><G><D><K><K><A><K><K><A>
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.<BOP>
A5ELM3
P34716
RECA_ACIFA
Recombinase A
Acidocella
<M><D><E><P><G><G><K><I><E><F><S><P><A><F><M><Q><I><E><G><Q><F><G><K><G><A><V><M><R><A><G><D><K><P><G><I><N><D><P><D><V><K><S><T><G><S><L><G><L><D><G><A><L><G><Q><G><G><L><P><R><G><R><V><V><E><I><Y><G><P><E><S><S><G><K><T><T><L><T><L><K><A><I><A><S><A><Q><A><E><G><A><T><P><A><F><T><D><A><E><H><A><L><D><P><G><F><A><S><K...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
P34716
Q6N6B8
RECO_RHOPA
Recombination protein O
Rhodopseudomonas
<M><E><W><S><D><E><G><I><I><L><G><V><R><R><H><G><E><S><A><A><I><V><E><L><L><T><R><G><H><G><R><H><L><G><M><V><R><G><G><A><S><A><R><M><R><P><L><L><Q><P><G><N><S><V><L><A><S><W><R><A><R><L><D><E><H><L><G><Y><Y><Q><L><E><A><T><K><M><R><A><A><T><L><L><G><S><S><H><A><V><Y><G><V><T><H><L><A><S><L><A><R><L><L><P><E><R><D><P><H...
Involved in DNA repair and RecF pathway recombination.<BOP>
Q6N6B8
B1ISA3
UXUA_ECOLC
D-mannonate hydro-lyase
Escherichia
<M><E><Q><T><W><R><W><Y><G><P><N><D><P><V><S><L><A><D><V><R><Q><A><G><A><T><G><V><V><T><A><L><H><H><I><P><N><G><E><V><W><S><V><E><E><I><L><K><R><K><A><I><V><E><D><A><G><L><V><W><S><V><V><E><S><V><P><I><H><E><D><I><K><T><H><T><G><N><Y><E><Q><W><I><A><N><Y><Q><Q><T><L><R><N><L><A><Q><C><G><I><R><T><V><C><Y><N><F><M><P><V...
Catalyzes the dehydration of D-mannonate.<BOP>
B1ISA3
P38454
CCMB_MARPO
ORF 277
Marchantia
<M><K><R><V><R><E><E><N><E><T><L><H><L><E><N><A><R><R><S><P><P><L><A><S><T><H><F><L><G><F><P><C><I><S><L><F><Y><S><Q><H><K><S><T><K><K><N><I><Y><L><D><L><K><T><K><K><K><E><L><L><P><M><V><F><A><L><R><A><F><K><I><F><L><K><L><F><Y><Q><H><I><L><L><N><L><S><T><L><I><T><T><F><S><L><F><L><L><Y><I><V><V><T><P><L><M><I><G><F><S...
May be involved in the export of heme to the mitochondrion for the biogenesis of c-type cytochromes.<BOP>
P38454
Q2H137
BCP1_CHAGB
Protein BCP1
Chaetomium
<M><G><K><K><R><S><R><D><A><D><G><Q><G><D><V><E><M><A><D><P><A><V><T><K><R><D><D><D><D><S><S><D><D><E><N><M><D><I><V><N><V><D><F><E><L><F><N><Y><D><S><Q><I><D><F><H><G><V><K><T><L><L><R><Q><L><F><D><T><D><A><Q><L><F><N><L><S><A><L><S><D><L><I><I><E><Q><N><T><I><G><S><T><C><K><V><D><D><K><A><N><D><A><Y><A><F><L><T><V><L...
Involved in nuclear export, actin cytoskeleton organization and vesicular transport.<BOP>
Q2H137
B2TNM9
DCDB_CLOBB
DCD-DUT
Clostridium
<M><I><L><S><G><K><E><I><L><K><H><I><G><E><D><I><V><I><E><P><F><S><E><E><R><I><N><P><N><S><Y><N><L><T><L><F><N><E><L><L><V><Y><K><N><E><T><L><D><M><K><I><P><N><E><T><E><K><L><I><I><P><E><E><G><L><L><L><E><P><G><K><L><Y><L><G><R><T><N><E><F><T><Q><T><N><K><Y><V><P><M><L><E><G><R><S><S><T><G><R><L><G><L><F><I><H><V><T><A...
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.<BOP>
B2TNM9
O33114
ILVC_MYCLE
Ketol-acid reductoisomerase type I
Mycobacterium
<M><F><Y><D><D><N><A><D><L><S><I><I><Q><R><R><K><V><G><V><I><G><Y><G><S><Q><G><Y><A><H><S><L><S><L><R><D><S><G><V><Q><V><R><V><G><L><P><E><G><S><K><S><R><P><K><A><F><E><Q><G><L><D><V><D><T><P><A><E><V><A><K><W><A><D><V><I><M><L><L><V><P><D><T><A><Q><A><D><V><F><E><N><D><I><E><P><N><L><Q><P><G><D><A><L><F><F><G><H><G><L...
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu...
O33114
A4IKT9
HPR_GEOTN
Protease production regulatory protein Hpr
Geobacillus
<M><K><S><T><E><Q><H><Y><S><I><K><E><A><M><L><F><S><Q><R><I><A><Q><L><S><K><A><L><W><K><S><I><E><K><D><W><Q><Q><W><I><K><P><F><N><L><N><I><N><E><H><H><I><L><W><I><A><Y><H><F><K><G><A><S><I><S><E><I><A><K><F><G><V><M><H><V><S><T><A><F><N><F><S><K><K><L><E><E><K><G><L><L><S><F><S><K><K><Q><D><D><K><R><N><T><Y><I><E><L><T...
Negative regulator of protease production and sporulation.<BOP>
A4IKT9
P95988
RS11_SACS2
30S ribosomal protein S11
Saccharolobus
<M><S><S><R><R><E><I><R><W><G><I><A><H><I><Y><A><S><Q><N><N><T><L><L><T><I><S><D><L><T><G><A><E><I><I><S><R><A><S><G><G><M><V><V><K><A><D><R><E><K><S><S><P><Y><A><A><M><L><A><A><N><K><A><A><S><D><A><L><E><K><G><I><M><A><L><H><I><K><V><R><A><P><G><G><Y><G><S><K><T><P><G><P><G><A><Q><P><A><I><R><A><L><A><R><A><G><F><I><I...
Located on the platform of the 30S subunit.<BOP>
P95988