accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
⌀
taxon
stringlengths
3
46
⌀
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
P40494
PRK1_YEAST
p53-regulating kinase 1
Saccharomyces
<M><N><T><P><Q><I><S><L><Y><E><P><G><T><I><L><T><V><G><S><H><H><A><K><I><I><K><Y><L><T><S><G><G><F><A><Q><V><Y><T><A><E><I><S><P><P><D><P><Y><S><N><A><N><I><A><C><L><K><R><V><I><V><P><H><K><Q><G><L><N><T><L><R><A><E><V><D><A><M><K><L><L><R><N><N><K><H><V><V><S><Y><I><D><S><H><A><A><R><S><V><N><G><I><A><Y><E><V><F><V><L...
Protein kinase involved in the regulation of actin cytoskeleton organization and endocytosis . Phosphorylates PAN1 which disrupts the interaction between PAN1 and END3, and between PAN1 and SLA1 . Phosphorylates SCD5 . Preferentially, phosphorylates substrates on threonine residues in a [L/I/V/M]-x-x-[Q/N/T/S]-x-T-G mo...
P40494
P40727
FLHB_SALTY
Flagellar biosynthetic protein FlhB
Salmonella
<M><A><E><E><S><D><D><D><K><T><E><A><P><T><P><H><R><L><E><K><A><R><E><E><G><Q><I><P><R><S><R><E><L><T><S><L><L><I><L><L><V><G><V><C><I><I><W><F><G><G><E><S><L><A><R><Q><L><A><G><M><L><S><A><G><L><H><F><D><H><R><M><V><N><D><P><N><L><I><L><G><Q><I><I><L><L><I><K><A><A><M><M><A><L><L><P><L><I><A><G><V><V><L><V><A><L><I><S...
Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.<BOP>
P40727
Q3A6N5
RL5_SYNC1
50S ribosomal protein L5
Syntrophotalea
<M><G><A><R><L><K><E><V><Y><S><T><E><I><A><P><A><L><V><K><R><L><Q><L><K><N><V><M><E><V><P><R><V><E><K><V><V><L><N><M><G><L><G><E><A><I><Q><N><I><K><V><L><E><S><A><V><E><E><L><T><R><I><C><G><Q><K><P><V><V><T><K><A><K><K><S><I><A><Q><F><K><L><R><E><G><M><P><I><G><C><M><V><T><L><R><R><D><K><A><Y><E><F><L><D><R><L><I><N><V...
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement...
Q3A6N5
P97051
NHAA_PSEPU
Nitrile hydratase subunit alpha
Pseudomonas
<M><G><Q><S><H><T><H><D><H><H><H><D><G><Y><Q><A><P><P><E><D><I><A><L><R><V><K><A><L><E><S><L><L><I><E><K><G><L><V><D><P><A><A><M><D><L><V><V><Q><T><Y><E><H><K><V><G><P><R><N><G><A><K><V><V><A><K><A><W><V><D><P><A><Y><K><A><R><L><L><A><D><A><T><A><A><I><A><E><L><G><F><S><G><V><Q><G><E><D><M><V><I><L><E><N><T><P><A><V><H...
NHase catalyzes the hydration of various nitrile compounds to the corresponding amides. Industrial production of acrylamide is now being developed using some of the enzymes of this class.<BOP>
P97051
Q9FKG6
PUB52_ARATH
Serine/threonine-protein kinase
Arabidopsis
<M><E><E><K><K><V><V><R><A><L><S><E><H><L><S><L><P><P><P><P><S><P><S><V><A><V><A><I><N><G><K><K><K><S><K><Y><V><V><F><W><A><L><E><K><F><I><P><E><G><F><T><D><F><K><L><L><Y><V><R><P><P><V><S><Y><I><P><T><P><M><G><I><A><V><A><V><S><E><L><R><E><D><V><V><S><A><Y><K><Q><E><L><D><W><S><A><N><E><M><L><R><P><Y><K><K><M><F><E><R...
Functions as an E3 ubiquitin ligase.<BOP>
Q9FKG6
A8LY23
RPOZ_SALAI
Transcriptase subunit omega
Salinispora
<M><G><T><I><A><T><N><P><E><G><I><T><N><P><P><I><D><E><L><L><E><K><T><T><S><K><Y><A><L><V><I><F><A><A><K><R><A><R><Q><V><N><A><Y><Y><S><Q><L><G><E><G><L><L><E><Y><V><G><P><L><V><E><T><T><P><Q><E><K><P><L><S><I><A><M><R><E><I><N><G><G><L><L><T><A><E><P><T><D><Q><P>
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP>
A8LY23
E0SNQ8
PUS10_IGNAA
tRNA pseudouridine 54/55 synthase
Ignisphaera
<M><S><I><I><D><I><A><N><N><I><L><R><K><Y><C><L><C><D><R><C><L><G><R><L><F><A><S><L><G><R><G><L><S><N><D><E><R><G><K><A><I><K><I><A><L><V><L><E><L><H><K><R><Y><L><D><G><D><K><D><S><L><K><Q><L><V><E><L><S><P><N><I><G><P><I><A><V><N><L><I><K><N><L><G><I><E><I><E><Y><T><P><R><T><C><F><I><C><D><N><K><I><N><D><I><I><D><T><Y...
Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.<BOP>
E0SNQ8
Q604W0
DDL_METCA
D-alanylalanine synthetase
Methylococcus
<M><E><K><R><I><Q><Q><A><S><K><F><G><K><V><A><V><L><M><G><G><S><A><A><E><R><E><I><S><L><K><S><G><K><A><V><L><E><A><L><R><S><G><G><I><D><A><E><G><I><D><V><G><R><D><L><I><A><P><L><L><E><R><R><F><D><R><V><F><N><V><I><H><G><R><G><G><E><D><G><V><L><Q><G><A><L><A><C><L><R><V><P><C><T><G><S><G><V><L><A><S><A><L><S><M><D><K><L...
Cell wall formation.<BOP>
Q604W0
Q2ITM9
SYA_RHOP2
Alanyl-tRNA synthetase
Rhodopseudomonas
<M><S><G><V><N><D><I><R><S><A><F><L><N><Y><F><A><K><N><G><H><D><I><V><P><S><S><P><L><V><P><R><N><D><P><T><L><M><F><T><N><A><G><M><V><Q><F><K><N><V><F><T><G><L><E><K><R><P><Y><Q><R><A><T><T><S><Q><K><C><V><R><A><G><G><K><H><N><D><L><D><N><V><G><Y><T><A><R><H><L><T><F><F><E><M><L><G><N><F><S><F><G><D><Y><F><K><E><R><A><I...
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.<BOP>
Q2ITM9
Q5E6Y8
EX7S_ALIF1
Exodeoxyribonuclease VII small subunit
Aliivibrio
<M><A><V><K><K><P><E><N><L><S><F><E><A><A><I><E><E><L><D><S><V><V><N><Q><L><E><S><G><D><L><P><L><E><D><A><L><K><K><F><E><R><G><I><S><L><A><R><A><G><Q><E><K><L><T><Q><A><E><Q><R><V><E><I><L><L><Q><A><D><D><N><A><E><L><T><P><F><D><G><Q><D><D>
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.<BOP>
Q5E6Y8
Q46HL3
NU1C_PROMT
NDH-A
Prochlorococcus
<M><N><S><G><I><D><L><E><M><S><F><T><Q><G><V><Q><N><L><G><L><S><H><E><L><A><H><L><L><W><I><P><L><P><M><L><L><V><L><V><S><A><V><I><G><V><L><V><T><V><W><L><E><R><K><I><S><A><A><A><Q><Q><R><I><G><P><E><Y><A><G><A><L><G><I><L><Q><P><M><A><D><G><L><K><L><L><V><K><E><D><I><I><P><A><R><A><D><S><V><L><F><T><V><G><P><I><L><V><L...
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus co...
Q46HL3
K4CEE8
C7A46_SOLLC
Cytochrome P450 716A46
Solanum subgen. Lycopersicon
<M><E><L><F><Y><A><S><L><V><C><L><F><V><L><L><L><S><L><S><F><L><F><L><F><N><K><K><N><K><S><M><I><L><S><C><P><L><P><P><G><N><S><G><W><P><V><I><G><E><T><L><E><F><L><S><T><G><W><K><G><H><P><E><K><F><I><F><D><R><I><S><K><Y><K><S><S><I><F><K><T><H><L><L><G><E><K><A><V><V><F><C><G><A><S><S><N><K><F><L><F><S><N><E><N><K><L><V...
Catalyzes the carboxylation of beta-amyrin at the C-28 position to form oleanolate . Catalyzes the carboxylation of alpha-amyrin at the C-28 position to form ursolate .<BOP>
K4CEE8
Q47UB2
RPOZ_COLP3
Transcriptase subunit omega
Colwellia
<M><A><R><V><T><V><E><D><A><V><D><K><V><G><N><R><F><D><L><V><L><V><A><S><R><R><A><R><Q><I><A><T><G><G><K><D><P><L><V><D><V><E><N><D><K><P><T><V><I><A><L><R><E><I><E><A><G><L><I><T><T><D><I><M><N><T><S><D><R><A><Q><Q><I><Q><Q><D><T><A><E><L><D><A><V><A><A><I><V><G><G><Q><Q><E><E><L><S>
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP>
Q47UB2
Q18CD1
ISPD_CLOD6
MEP cytidylyltransferase
Clostridioides
<M><Y><S><V><I><I><V><A><A><G><S><G><R><R><M><N><L><D><I><N><K><Q><F><I><K><L><R><E><K><E><I><I><A><H><T><I><Q><V><F><Y><E><N><I><N><I><D><E><I><V><V><C><I><K><K><E><E><E><D><F><F><K><E><N><I><I><N><K><Y><N><F><K><N><I><K><I><A><Y><G><G><K><E><R><Q><D><S><I><Y><N><G><L><K><K><L><D><K><N><C><D><I><V><L><I><H><D><G><A><R...
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP>
Q18CD1
Q2G5S0
PLSX_NOVAD
Phosphate-acyl-ACP acyltransferase
Novosphingobium
<M><S><L><P><R><I><A><V><D><A><M><G><G><D><E><G><V><R><V><M><V><E><G><A><A><L><A><R><R><R><H><D><R><F><K><F><L><L><V><G><D><E><A><R><I><K><Q><A><L><E><N><H><P><N><L><R><G><A><S><E><I><L><H><A><P><D><I><V><S><G><D><E><K><P><T><Q><A><L><R><R><A><K><T><T><S><M><G><M><A><I><N><A><V><K><R><G><E><A><G><A><A><V><S><A><G><N><T...
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.<BOP>
Q2G5S0
I1S3T9
XYNC_GIBZE
1,4-beta-D-xylan xylanohydrolase C
Fusarium
<M><K><F><S><S><L><L><F><T><A><S><L><V><A><A><M><P><A><S><I><E><P><R><Q><A><Q><E><S><I><N><K><L><I><K><A><K><G><K><L><Y><Y><G><T><I><T><D><P><N><L><L><Q><S><Q><Q><N><N><A><V><I><K><A><D><F><G><Q><V><T><P><E><N><S><M><K><W><D><A><T><E><P><Q><Q><G><K><F><N><F><G><G><G><D><Q><V><V><N><F><A><A><Q><N><G><L><K><V><R><G><H><A...
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Plays an important role in causing fusarium head blight (FHB) on cereal crops.<BOP>
I1S3T9
Q8DD21
RL7_VIBVU
50S ribosomal protein L7/L12
Vibrio
<M><S><I><T><N><E><Q><I><L><D><A><I><A><E><M><S><V><T><Q><V><V><E><L><I><S><A><M><E><E><K><F><G><V><T><A><A><A><A><V><V><A><G><G><A><A><A><G><A><A><V><E><E><Q><T><E><F><N><V><I><L><A><S><A><G><A><N><K><V><A><V><I><K><A><V><R><G><A><T><G><L><G><L><K><E><A><K><A><L><V><D><G><A><P><A><A><L><K><E><G><V><E><K><A><E><A><E><A...
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.<BOP>
Q8DD21
P70313
NOS3_MOUSE
NOS type III
Mus
<M><G><N><L><K><S><V><G><Q><E><P><G><P><P><C><G><L><G><L><G><L><G><L><G><L><C><G><K><Q><G><P><A><S><P><A><P><E><P><S><Q><A><P><A><P><P><S><P><T><R><P><A><P><D><H><S><P><P><L><T><R><P><P><D><G><P><R><F><P><R><V><K><N><W><E><V><G><S><I><T><Y><D><T><L><S><A><Q><A><Q><Q><D><G><P><C><T><S><R><R><C><L><G><S><L><V><F><P><R><K...
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. May play a significant ...
P70313
A9I0G7
PYRE_BORPD
Orotate phosphoribosyltransferase
Bordetella
<M><A><A><A><S><A><T><S><T><D><F><V><R><F><A><L><D><E><G><V><L><R><F><G><S><F><K><V><K><S><G><R><T><S><P><Y><F><F><N><A><G><L><F><N><S><G><A><S><V><G><R><L><A><Q><F><Y><A><Q><A><L><V><D><S><G><I><A><F><D><M><L><F><G><P><A><Y><K><G><I><P><L><A><T><A><T><A><V><A><L><A><G><H><P><A><M><Q><G><R><D><V><P><F><A><F><N><R><K><E...
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).<BOP>
A9I0G7
Q04SI9
ENO_LEPBJ
2-phosphoglycerate dehydratase
Leptospira
<M><S><H><N><S><Q><I><Q><K><I><Q><A><R><E><I><I><D><S><R><G><N><P><T><V><E><V><D><V><T><L><M><D><G><S><F><G><R><A><A><V><P><S><G><A><S><T><G><E><Y><E><A><V><E><L><R><D><G><D><K><Q><R><Y><L><G><K><G><V><L><K><A><V><E><H><V><N><V><K><I><Q><E><I><L><K><G><Q><D><A><L><D><Q><N><R><V><D><Q><L><M><L><D><A><D><G><T><K><N><K><G...
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP>
Q04SI9
A1AG46
KBAY_ECOK1
Tagatose-bisphosphate aldolase
Escherichia
<M><S><I><I><S><T><K><Y><L><L><Q><D><A><Q><A><N><G><Y><A><V><P><A><F><N><I><H><N><A><E><T><I><Q><A><I><L><E><V><C><S><E><M><R><S><P><V><I><L><A><G><T><P><G><T><F><K><H><I><A><L><E><E><I><Y><A><L><C><S><A><Y><S><T><T><Y><N><M><P><L><A><L><H><L><D><H><H><E><S><L><D><D><I><R><R><K><V><H><A><G><V><R><S><A><M><I><D><G><S><H...
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires KbaZ subunit for full activity and stability.<BOP>
A1AG46
A0A087WT02
TVA92_HUMAN
T cell receptor alpha variable 9-2
Homo
<M><N><Y><S><P><G><L><V><S><L><I><L><L><L><L><G><R><T><R><G><D><S><V><T><Q><M><E><G><P><V><T><L><S><E><E><A><F><L><T><I><N><C><T><Y><T><A><T><G><Y><P><S><L><F><W><Y><V><Q><Y><P><G><E><G><L><Q><L><L><L><K><A><T><K><A><D><D><K><G><S><N><K><G><F><E><A><T><Y><R><K><E><T><T><S><F><H><L><E><K><G><S><V><Q><V><S><D><S><A><V><Y...
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition . Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (...
A0A087WT02
Q57HG9
RHAB_SALCH
Rhamnulose kinase
Salmonella
<M><T><F><R><H><C><V><A><V><D><L><G><A><S><S><G><R><V><M><L><A><R><Y><D><S><K><H><R><T><L><T><L><R><E><I><H><R><F><V><N><C><L><Q><K><T><D><G><F><D><T><W><D><I><D><S><L><E><K><D><I><R><L><G><L><K><K><V><C><N><E><G><I><L><I><D><S><I><G><I><D><T><W><G><V><D><Y><V><L><L><D><K><Q><G><Q><R><V><G><L><P><V><S><Y><R><D><N><R><T...
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.<BOP>
Q57HG9
Q40253
L6_LINUS
NADP(+) hydrolase L6
Linum
<M><S><Y><L><R><E><V><A><T><A><V><A><L><L><L><P><F><I><L><L><N><K><F><W><R><P><N><S><K><D><S><I><V><N><D><D><D><D><S><T><S><E><V><D><A><I><S><D><S><T><N><P><S><G><S><F><P><S><V><E><Y><E><V><F><L><S><F><R><G><P><D><T><R><E><Q><F><T><D><F><L><Y><Q><S><L><R><R><Y><K><I><H><T><F><R><D><D><D><E><L><L><K><G><K><E><I><G><P><N...
TIR-NB-LRR receptor-like protein that confers resistance to the flax rust phytopathogenic fungus (M.lini) . Acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death . Also ...
Q40253
P0CD31
NU2C2_PIPCE
NADH-plastoquinone oxidoreductase subunit 2 B
Piper
<M><I><W><H><V><Q><N><E><N><F><I><L><D><S><T><R><I><F><M><K><A><F><H><L><L><L><F><H><G><S><F><I><F><P><E><C><I><L><I><F><G><L><I><L><L><L><M><I><D><S><T><S><D><Q><K><D><I><P><W><L><Y><F><I><S><S><T><S><L><V><M><S><I><T><A><L><L><F><R><W><R><E><E><P><M><I><S><F><S><G><N><F><Q><T><N><N><F><N><E><I><F><Q><F><L><I><L><L><C...
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translo...
P0CD31
A9QC94
PSBB_TRACE
Protein CP-47
Trachelium
<M><G><L><P><W><Y><R><V><H><T><I><V><L><N><D><P><G><R><L><L><A><V><H><I><M><H><T><A><L><V><A><G><W><A><G><S><M><A><L><Y><E><L><A><V><F><D><P><S><D><P><V><L><D><P><M><W><R><Q><G><M><F><V><I><P><F><M><T><R><L><G><I><I><N><S><W><G><G><W><G><I><T><G><G><T><I><T><Y><P><G><I><W><S><Y><E><G><V><A><G><A><H><I><V><F><S><G><L><C...
One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient sub...
A9QC94
C3P1G4
UPP_BACAA
UPRTase
Bacillus cereus group
<M><G><K><L><Y><V><F><D><H><P><L><I><Q><H><K><I><T><Y><I><R><D><K><N><T><G><T><K><D><F><R><E><L><V><D><E><V><A><S><L><M><A><F><E><I><T><R><D><L><P><L><K><D><I><E><I><E><T><P><V><S><K><A><T><T><K><V><I><A><G><K><K><L><G><L><I><P><I><L><R><A><G><L><G><M><V><D><G><I><L><K><L><I><P><A><A><K><V><G><H><V><G><L><Y><R><D><P><K...
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP>
C3P1G4
Q8XBR9
PAGP_ECO57
Lipid A acylation protein
Escherichia
<M><N><V><S><K><Y><V><A><I><F><S><F><V><F><I><Q><L><I><S><V><G><K><V><F><A><N><A><D><E><W><M><T><T><F><R><E><N><I><V><Q><T><W><Q><Q><P><E><H><Y><D><L><Y><I><P><A><I><T><W><H><A><R><F><A><Y><D><K><E><K><T><D><R><Y><N><E><R><P><W><G><G><G><F><G><L><S><R><W><D><E><K><G><N><W><H><G><L><Y><A><M><A><F><K><D><S><W><N><K><W><E...
Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors.<BOP>
Q8XBR9
A0Q2Z4
ATPB_CLONN
F-ATPase subunit beta
Clostridium
<M><P><D><N><N><V><G><R><V><V><Q><V><I><G><P><V><I><D><I><K><F><D><S><D><C><L><P><N><I><Y><N><A><I><E><I><D><M><G><D><R><I><L><I><T><E><V><E><Q><H><I><G><D><D><V><V><R><T><I><A><M><E><S><T><E><G><L><K><R><G><M><K><A><V><N><T><E><K><P><I><S><V><P><V><G><S><E><I><L><G><R><L><F><N><V><L><G><K><T><I><D><E><E><G><E><F><K><A...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP>
A0Q2Z4
C3MZM9
RPO1C_SULIA
DNA-directed RNA polymerase subunit A''
Sulfolobus
<M><I><D><E><K><D><K><S><Y><L><E><E><K><V><K><Q><A><S><N><I><L><P><Q><K><I><V><E><D><L><K><N><L><I><S><N><K><E><V><L><V><T><R><D><E><I><D><K><I><F><D><L><A><I><K><E><Y><S><E><G><L><I><A><P><G><E><A><I><G><I><V><A><A><Q><S><V><G><E><P><G><T><Q><M><T><L><R><T><F><H><F><A><G><I><R><E><L><N><V><T><L><G><L><P><R><L><I><E><I...
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.<BOP>
C3MZM9
Q0WQE7
AUG3_ARATH
AUGMIN subunit 3
Arabidopsis
<M><S><S><A><R><L><C><S><L><V><A><E><L><G><Y><E><G><A><G><K><L><D><P><D><S><F><E><W><P><F><Q><Y><D><D><A><R><P><I><L><D><W><I><C><S><S><L><R><P><S><N><V><L><S><L><A><E><L><S><L><Y><E><Q><F><Q><R><D><G><K><L><L><E><G><D><D><L><D><Q><A><Y><D><S><I><S><A><F><S><S><R><R><N><N><Q><E><A><V><F><G><A><E><E><S><I><K><E><V><R><D...
Involved in microtubules reorganization during spindle and phragmoplast development. Required for gamma-tubulin localization during mitosis.<BOP>
Q0WQE7
Q5WSK5
LPXD2_LEGPL
UDP-3-O-acylglucosamine N-acyltransferase 2
Legionella
<M><S><N><Y><Q><F><T><K><P><A><G><P><F><Y><L><A><E><L><A><E><I><S><G><S><T><L><Y><E><G><K><G><E><A><F><T><V><S><G><L><A><K><L><S><E><A><T><T><H><N><L><V><M><L><H><Q><K><K><Y><L><K><E><L><K><N><T><A><A><R><A><C><I><I><G><P><E><Y><V><K><F><A><P><D><S><M><Y><L><L><V><H><P><N><P><Y><K><A><F><A><L><I><A><Q><A><F><Y><P><S><E...
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP>
Q5WSK5
P13079
CARB_STRTH
Carbomycin-resistance protein
Streptomyces
<M><A><A><L><L><K><R><I><L><R><R><R><M><A><E><K><R><S><G><R><G><R><M><A><A><A><R><T><T><G><A><Q><S><R><K><T><A><Q><R><S><G><R><S><E><A><D><R><R><R><R><V><H><G><Q><N><F><L><V><D><R><E><T><V><Q><R><F><V><R><F><A><D><P><D><P><G><E><V><V><L><E><V><G><A><G><N><G><A><I><T><R><E><L><A><R><L><C><R><R><V><V><A><Y><E><I><D><R><H...
Probable RNA methylase. Confers resistance to carbomycin and several other macrolides, lincomycin and vernamycin B, but not to all macrolide-lincosamide-streptogramin B antibiotics.<BOP>
P13079
O51723
NADD_BORBU
Nicotinate mononucleotide adenylyltransferase
Borreliella
<M><R><I><A><I><L><G><G><T><Y><N><P><V><H><I><G><H><I><F><L><A><K><E><I><E><Y><L><L><N><I><D><R><V><I><F><I><P><T><C><N><P><A><H><K><L><I><D><E><N><V><S><V><S><N><R><I><D><M><L><K><L><A><L><E><N><E><D><K><M><F><I><D><D><C><D><I><I><N><G><G><I><T><Y><T><V><D><T><I><S><C><V><K><K><K><Y><K><N><D><K><L><F><L><I><I><G><D><D...
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).<BOP>
O51723
O32445
NAGA_VIBCH
N-acetylglucosamine-6-phosphate deacetylase
Vibrio
<M><Y><A><L><T><N><C><K><I><Y><T><G><N><D><V><L><V><K><H><A><V><I><I><N><G><D><K><I><E><A><V><C><P><I><E><S><L><P><S><E><M><N><V><V><D><L><N><G><A><N><L><S><P><G><F><I><D><L><Q><L><N><G><C><G><G><V><M><F><N><D><E><I><T><A><E><T><I><D><T><M><H><K><A><N><L><K><S><G><C><T><S><F><L><P><T><L><I><T><S><S><D><E><N><M><R><Q><A...
Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N-acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate.<BOP>
O32445
A4Y9B5
PNP_SHEPC
null
Shewanella
<M><N><P><I><V><K><S><F><E><Y><G><Q><H><T><V><T><L><E><T><G><V><I><A><R><Q><A><D><A><A><V><L><A><S><M><G><D><T><T><V><L><V><T><V><V><G><K><K><E><A><E><A><G><R><D><F><F><P><L><T><V><N><Y><Q><E><K><T><Y><A><A><G><K><I><P><G><G><F><F><K><R><E><G><R><P><S><E><D><E><T><L><I><A><R><L><I><D><R><P><I><R><P><L><F><P><N><G><F><K...
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.<BOP>
A4Y9B5
Q602B7
SYI_MESH2
Isoleucyl-tRNA synthetase
Mesomycoplasma
<M><D><K><N><F><Y><K><N><S><L><N><I><F><N><S><N><F><S><M><K><A><N><L><S><E><K><D><K><F><Y><A><D><F><W><E><K><N><Q><I><Y><Q><Q><I><L><R><K><R><R><G><N><P><R><F><I><L><H><D><G><P><P><Y><A><N><G><D><I><H><I><G><H><A><L><N><K><I><L><K><D><I><I><V><R><Y><K><T><M><A><G><F><Y><S><P><F><V><P><G><W><D><T><H><G><L><P><I><E><N><K...
Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrol...
Q602B7
P43263
NPRE_BREBE
Neutral protease
Brevibacillus
<M><K><K><S><Y><L><A><T><S><L><T><L><S><I><A><V><G><V><S><G><F><T><S><V><P><A><F><A><K><T><K><I><D><Y><H><K><Q><W><D><T><P><Q><Y><I><G><E><V><W><E><P><E><G><A><K><G><D><D><V><V><W><S><Y><L><E><K><Y><K><D><E><F><R><I><Q><G><N><V><E><D><H><F><E><I><V><N><E><A><R><N><K><E><T><D><T><K><H><Y><R><L><Q><E><V><Y><N><G><I><P><I...
Extracellular zinc metalloprotease.<BOP>
P43263
A7MKJ6
EFG_CROS8
Elongation factor G
Cronobacter
<M><A><R><T><T><P><I><A><R><Y><R><N><I><G><I><S><A><H><I><D><A><G><K><T><T><T><T><E><R><I><L><F><Y><T><G><V><N><H><K><I><G><E><V><H><D><G><A><A><T><M><D><W><M><E><Q><E><Q><E><R><G><I><T><I><T><S><A><A><T><T><A><F><W><S><G><M><A><K><Q><Y><E><P><H><R><I><N><I><I><D><T><P><G><H><V><D><F><T><I><E><V><E><R><S><M><R><V><L><D...
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respective...
A7MKJ6
A5FJ95
PDXJ_FLAJ1
Pyridoxine 5'-phosphate synthase
Flavobacterium
<M><T><K><L><S><V><N><I><N><K><I><A><T><L><R><N><A><R><G><G><N><V><P><D><L><L><K><V><A><A><D><I><Q><R><F><G><G><Q><G><I><T><I><H><P><R><P><D><E><R><H><I><R><Y><Q><D><A><R><D><L><K><A><I><V><T><T><E><Y><N><I><E><G><N><P><Q><H><N><F><I><D><L><V><L><E><C><K><P><D><Q><V><T><L><V><P><D><A><I><G><A><I><T><S><S><A><G><W><D><T...
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.<BOP>
A5FJ95
Q9C8T9
DRL19_ARATH
Putative disease resistance protein At1g63350
Arabidopsis
<M><G><I><S><F><S><I><P><F><D><P><C><V><N><K><V><S><Q><W><L><D><M><K><V><S><Y><T><H><N><L><E><K><N><L><V><A><L><E><T><T><M><E><E><L><K><A><K><R><D><D><L><L><R><K><L><K><R><E><E><D><R><G><L><Q><T><L><G><E><I><K><V><W><L><N><R><V><E><T><I><E><S><R><V><N><D><L><L><N><A><R><N><A><E><L><Q><R><L><C><L><C><G><F><C><S><K><S><L...
Potential disease resistance protein.<BOP>
Q9C8T9
A3PU80
MURB_MYCSJ
UDP-N-acetylmuramate dehydrogenase
unclassified Mycobacterium
<M><T><G><Q><E><L><A><G><A><E><V><E><A><D><V><A><L><A><P><L><T><T><L><R><V><G><P><V><A><R><R><L><I><T><A><T><S><T><E><Q><L><V><A><A><L><R><A><P><V><G><R><D><A><L><I><L><A><G><G><S><N><V><V><L><A><D><D><M><A><D><L><T><V><I><R><V><A><N><S><E><I><T><V><H><D><G><I><V><R><A><E><A><G><A><N><W><D><D><V><V><V><T><A><L><A><H><G...
Cell wall formation.<BOP>
A3PU80
G3XDA7
FTSQ_PSEAE
Cell division protein FtsQ
Pseudomonas
<M><N><G><V><L><L><R><H><Q><Q><P><G><G><L><G><R><A><P><R><K><P><M><P><R><G><A><S><R><L><V><A><K><E><P><L><S><V><R><L><P><K><A><D><F><S><F><L><K><Y><L><A><W><P><L><L><L><A><V><L><G><Y><G><A><Y><R><G><A><E><Y><I><L><P><Y><A><D><R><P><I><A><K><V><S><V><E><G><D><L><S><Y><I><S><Q><R><A><V><Q><Q><R><I><S><P><Y><L><A><A><S><F...
Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.<BOP>
G3XDA7
Q8UF87
SSB_AGRFC
Single-stranded DNA-binding protein
Agrobacterium tumefaciens complex
<M><A><G><S><V><N><K><V><I><L><I><G><N><V><G><A><D><P><E><I><R><R><T><Q><D><G><R><P><I><A><N><L><R><I><A><T><S><E><T><W><R><D><R><N><S><G><E><R><K><E><K><T><E><W><H><T><V><V><V><F><N><E><G><L><C><K><V><V><E><Q><Y><V><K><K><G><A><K><L><Y><I><E><G><Q><L><Q><T><R><K><W><Q><D><Q><T><G><N><D><R><Y><S><T><E><I><V><L><Q><G><F...
Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.<BOP>
Q8UF87
Q977U8
RS8_METTL
30S ribosomal protein S8
Methanothermococcus
<M><S><L><M><D><P><L><A><N><A><L><N><H><I><S><N><C><E><G><V><G><K><S><V><A><Y><V><K><P><A><S><K><L><I><G><R><V><L><N><V><M><Q><D><H><G><Y><I><G><N><F><E><Y><I><E><D><G><R><A><G><I><Y><K><V><E><L><I><G><Q><I><N><K><C><G><A><V><K><P><R><Y><A><V><K><K><Q><E><F><E><K><F><E><K><R><Y><L><P><A><K><G><F><G><L><L><I><V><S><T><P...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP>
Q977U8
P02238
LGBA_SOYBN
Nodulin-2
Glycine subgen. Soja
<M><V><A><F><T><E><K><Q><D><A><L><V><S><S><S><F><E><A><F><K><A><N><I><P><Q><Y><S><V><V><F><Y><T><S><I><L><E><K><A><P><A><A><K><D><L><F><S><F><L><A><N><G><V><D><P><T><N><P><K><L><T><G><H><A><E><K><L><F><A><L><V><R><D><S><A><G><Q><L><K><A><S><G><T><V><V><A><D><A><A><L><G><S><V><H><A><Q><K><A><V><T><D><P><Q><F><V><V><V><K...
Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.<BOP>
P02238
Q5WWW0
ERPA_LEGPL
Iron-sulfur cluster insertion protein ErpA
Legionella
<M><A><S><V><D><V><S><Q><N><T><S><D><I><N><F><S><V><S><A><A><D><K><V><A><E><L><I><K><E><E><D><N><S><D><L><N><L><R><V><S><I><T><G><G><G><C><S><G><F><Q><Y><G><F><S><F><D><E><Q><I><N><D><D><D><T><V><I><I><Q><Q><C><S><D><G><K><S><S><V><K><L><L><I><D><S><M><S><Y><Q><Y><L><H><D><A><E><I><D><Y><I><K><G><I><Q><G><E><Q><F><V><I...
Required for insertion of 4Fe-4S clusters for at least IspG.<BOP>
Q5WWW0
Q2HXL0
RBOHC_SOLTU
StRBOHC
Solanum
<M><Q><N><S><E><N><H><H><P><H><H><H><H><H><H><S><D><T><E><I><I><G><N><D><R><A><S><Y><S><G><P><L><S><G><P><L><N><K><R><G><G><K><K><S><A><R><F><N><I><P><E><S><T><D><I><G><T><S><A><G><A><G><A><K><S><N><D><D><A><Y><V><E><I><T><L><D><V><R><E><D><S><V><A><V><H><S><V><K><T><A><G><G><A><D><V><E><D><P><E><L><A><L><L><A><K><G><L...
Calcium-dependent NADPH oxidase that generates superoxide. May be responsible for the oxidative burst in response to pathogen attack in the leaves.<BOP>
Q2HXL0
A9VFD5
MTNA_BACMK
S-methyl-5-thioribose-1-phosphate isomerase
Bacillus cereus group
<M><S><T><I><I><T><I><P><R><S><V><S><W><K><G><D><A><I><A><V><L><N><Q><T><K><L><P><H><V><T><E><Y><K><T><L><T><N><I><E><D><V><W><K><S><I><I><M><L><E><V><R><G><A><P><A><I><G><I><V><A><A><F><G><L><A><L><A><A><K><K><Y><D><A><I><N><I><Y><E><F><Q><K><K><F><N><R><D><C><N><Y><L><G><T><S><R><P><T><A><V><N><L><F><W><A><I><D><R><M...
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).<BOP>
A9VFD5
Q5FGD5
ARGC_EHRRG
N-acetyl-glutamate semialdehyde dehydrogenase
Ehrlichia
<M><S><Y><Q><V><S><V><A><V><V><G><A><T><G><Y><V><G><V><E><L><V><R><L><L><L><F><H><P><M><V><K><I><K><Y><L><C><A><T><Q><S><I><G><S><L><L><S><S><H><Y><D><H><V><L><K><D><S><I><P><V><S><I><S><C><F><S><S><I><D><L><S><K><V><D><V><I><F><L><C><L><P><H><G><Q><S><N><E><I><V><K><K><I><H><N><E><V><K><I><I><I><D><L><S><A><D><F><R><I...
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.<BOP>
Q5FGD5
A5WDY5
COQ7_PSYWF
2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase
Psychrobacter
<M><A><K><N><L><S><I><I><D><R><A><I><V><G><F><D><S><S><L><R><A><I><I><P><H><S><N><Q><T><A><R><P><L><P><V><S><S><D><A><L><P><Q><L><S><I><T><E><S><R><H><V><A><G><L><M><R><I><N><H><T><G><E><V><C><A><Q><G><L><Y><H><G><Q><A><F><T><A><K><D><D><L><V><K><Q><A><M><Q><H><S><A><D><E><E><I><D><H><L><V><W><C><E><T><R><L><D><E><L><G...
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.<BOP>
A5WDY5
Q86SQ6
AGRA1_HUMAN
G-protein coupled receptor 123
Homo
<M><D><L><K><T><V><L><S><L><P><R><Y><P><G><E><F><L><H><P><V><V><Y><A><C><T><A><V><M><L><L><C><L><L><A><S><F><V><T><Y><I><V><H><Q><S><A><I><R><I><S><R><K><G><R><H><T><L><L><N><F><C><F><H><A><A><L><T><F><T><V><F><A><G><G><I><N><R><T><K><Y><P><I><L><C><Q><A><V><G><I><V><L><H><Y><S><T><L><S><T><M><L><W><I><G><V><T><A><R><N...
Orphan receptor.<BOP>
Q86SQ6
O36051
RR4_NEOSP
30S ribosomal protein S4, chloroplastic
unclassified Neomarica
<R><F><K><K><I><R><R><L><G><A><L><P><G><L><T><S><K><R><P><R><S><G><S><D><L><K><N><Q><L><R><S><G><K><R><S><Q><Y><R><I><R><L><E><E><K><Q><K><L><R><F><H><Y><G><L><T><E><R><Q><L><L><K><Y><V><H><I><A><G><K><A><K><G><S><T><G><Q><V><L><L><Q><L><L><E><M><R><L><D><N><I><L><F><R><L><G><M><A><S><T><I><P><G><A><R><Q><L><V><N><H><R...
With S5 and S12 plays an important role in translational accuracy.<BOP>
O36051
Q8TT89
RIBB_METAC
3,4-dihydroxy-2-butanone 4-phosphate synthase
Methanosarcina
<M><N><E><S><T><V><Y><E><C><L><K><Y><G><N><E><N><I><N><R><A><L><E><V><L><R><A><G><K><M><I><Q><I><Y><D><S><D><S><R><E><G><E><T><D><L><V><I><P><A><K><A><V><T><Y><K><D><V><K><W><M><R><K><D><A><G><G><L><I><C><V><A><V><D><P><V><A><S><K><Q><L><K><L><P><F><M><A><D><L><V><R><E><A><S><R><T><S><E><S><L><G><E><V><V><E><K><D><G><D...
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.<BOP>
Q8TT89
B5Y342
PSD_KLEP3
Phosphatidylserine decarboxylase beta chain
Klebsiella
<M><L><N><D><L><K><L><S><L><Q><Y><I><L><P><K><L><W><L><T><R><L><A><G><W><G><A><S><K><R><A><G><W><L><T><K><L><V><I><D><L><F><V><K><Y><Y><K><V><D><M><K><E><A><Q><K><P><D><T><A><A><Y><R><T><F><N><D><F><F><V><R><P><L><R><D><D><V><R><P><L><N><T><D><P><N><V><L><V><M><P><A><D><G><V><I><S><Q><L><G><A><I><E><D><D><K><I><L><Q><A...
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).<BOP>
B5Y342
Q6F7T4
RS13_ACIAD
30S ribosomal protein S13
Acinetobacter
<M><A><R><I><A><G><V><N><I><P><D><N><K><H><A><V><I><S><L><T><Y><I><F><G><V><G><R><H><T><A><K><S><I><L><A><A><V><G><I><G><P><T><T><K><I><R><E><L><D><D><A><Q><L><D><A><I><R><A><E><V><A><K><V><P><T><E><G><D><L><R><R><E><I><S><M><N><I><K><R><L><M><D><L><G><C><Y><R><G><L><R><H><R><R><S><L><P><V><R><G><Q><R><T><K><T><N><A><R...
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.<...
Q6F7T4
B8DA57
HIS1_LISMH
ATP phosphoribosyltransferase
Listeria
<M><K><A><L><K><I><A><L><T><K><G><R><L><E><K><D><A><V><A><L><L><E><K><A><G><I><D><C><S><S><M><T><D><K><K><R><K><L><I><F><H><S><S><T><Q><P><I><S><F><I><L><V><K><A><V><D><V><M><T><Y><V><K><H><G><V><A><D><I><G><I><V><G><K><D><V><L><M><E><A><S><K><S><H><Y><E><M><L><D><L><E><I><G><K><C><Q><F><C><L><A><S><T><P><D><F><D><P><S...
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.<BOP>
B8DA57
P0C092
CSEN4_MOUSE
Calsenilin isoform 4
Mus
<M><R><Q><L><P><A><G><P><S><S><L><A><C><S><G><C><K><A><G><R><L><V><T><V><P><F><S><S><R><D><A><E><D><Q><G><S><R><E><G><I><G><W><Q><P><P><G><R><S><W><A><H><T><T><E><Q><E><G><K><H><Q><V><A><K><A><T><V><H><P><P><G><P><D><A><L><L><L><N><Q><V><D><P><V><Q><C><C><P><T><R><L>
Unknown for isoform 4. Csen is involved in calcium-dependent transcriptional repression, regulation of potassium channels, and perhaps in processing of PSEN2 and apoptosis.<BOP>
P0C092
Q034Y5
RL23_LACP3
50S ribosomal protein L23
Lacticaseibacillus
<M><E><A><R><D><I><I><L><R><P><I><V><T><E><Q><S><M><A><E><M><D><N><R><K><Y><T><F><E><V><A><L><H><A><T><K><P><Q><V><R><K><A><V><E><E><I><F><G><V><K><V><V><N><V><N><I><A><N><V><R><G><K><K><K><R><Q><G><R><Y><E><G><M><T><R><R><R><R><K><A><L><I><A><L><S><A><D><S><K><E><I><K><I><F><A><D><E><D><N><D><K><K>
One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.<BOP>
Q034Y5
C5FNB5
LAP5_ARTOC
Probable leucine aminopeptidase MCYG_04170
Microsporum
<M><K><V><L><A><A><L><A><L><S><A><L><A><L><A><K><P><T><P><P><M><P><G><M><S><L><I><Q><T><G><P><Q><E><T><R><W><V><T><D><A><E><K><L><E><L><T><M><N><N><V><G><F><F><D><I><T><D><M><P><V><T><A><S><S><V><T><K><P><K><S><Y><A><F><P><G><N><V><S><H><Q><A><D><V><K><P><L><L><G><K><L><S><S><D><H><L><M><S><N><L><Q><K><F><S><D><F><P><N...
Probable extracellular aminopeptidase which contributes to pathogenicity.<BOP>
C5FNB5
Q2YIQ4
ERYD_BRUA2
Erythritol catabolism regulatory protein EryD
Brucella
<M><A><D><A><D><D><S><L><A><L><R><A><A><W><L><H><F><V><A><G><M><T><Q><S><A><V><A><K><R><L><G><L><P><S><V><K><A><H><R><L><I><A><K><A><V><A><D><G><A><V><K><V><T><I><D><G><D><I><T><E><C><I><D><L><E><N><R><L><A><D><L><Y><G><L><D><Y><C><E><V><A><P><D><I><G><E><E><G><L><P><L><M><A><L><G><H><A><G><A><N><F><M><R><R><E><I><E><H...
Represses the expression of the eryABCD operon, which is involved in erythritol catabolism.<BOP>
Q2YIQ4
Q4WJ81
CRZA_ASPFU
C2H2 finger domain transcription factor crzA
Aspergillus subgen. Fumigati
<M><A><S><Q><E><M><F><P><E><L><G><Q><S><P><A><P><G><V><K><S><R><G><V><S><R><S><P><H><P><H><Q><Q><Q><Q><Q><Q><Q><H><Q><Q><H><Q><G><Q><F><T><G><T><V><T><G><L><D><L><D><S><S><I><A><T><A><S><S><F><A><N><S><S><F><D><P><N><S><N><N><V><S><P><S><A><E><S><Y><G><Y><T><A><A><G><Y><L><S><G><T><P><A><S><Q><T><D><Q><N><Y><A><N><S><L...
Transcription factor involved in the regulation of calcium ion homeostasis . Regulates genes encoding calcium transporters, transcription factors and genes that could be directly or indirectly involved in calcium metabolism . Supports especially pmcA, pmcB and pmcC expression encoding for calcium-translocating P-type A...
Q4WJ81
B4TRX1
RLMKL_SALSV
rRNA (guanine-N(7)-)-methyltransferase RlmK
Salmonella
<M><N><S><L><F><A><S><T><A><R><G><L><E><E><L><L><K><T><E><L><E><K><L><G><A><V><G><C><Q><V><V><Q><G><G><V><H><F><Q><G><D><T><R><L><I><Y><Q><S><L><M><W><S><R><L><A><S><R><I><I><L><P><M><G><E><C><K><V><Y><S><D><L><D><L><Y><L><G><V><Q><A><I><N><W><T><E><I><F><N><P><G><A><T><F><A><V><H><F><S><G><L><N><D><T><I><R><N><S><Q><Y...
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.<BOP>
B4TRX1
Q6A6V2
TSAD_CUTAK
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Cutibacterium
<M><S><E><P><L><I><L><G><I><E><S><S><C><D><E><T><G><V><G><I><V><R><G><N><D><L><L><A><N><E><V><A><S><S><M><E><Q><H><V><R><F><G><G><V><V><P><E><V><A><S><R><A><H><L><E><A><I><V><P><V><L><D><K><A><A><S><T><A><G><V><D><L><S><E><L><D><G><I><A><V><T><A><G><P><G><L><A><G><A><L><V><V><G><L><S><A><A><K><A><L><A><S><W><L><N><K><P...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
Q6A6V2
P22940
TSAG_ORITS
TSG56
Orientia
<M><K><K><I><M><L><I><A><S><A><M><S><A><L><S><L><P><F><S><A><S><A><I><E><L><G><E><E><G><G><L><E><C><G><P><Y><G><K><V><G><I><V><G><G><M><I><T><G><A><E><S><T><R><L><D><S><T><D><S><E><G><K><K><H><L><S><L><T><T><G><L><P><F><G><G><T><L><A><A><G><M><T><I><A><P><G><F><R><A><E><L><G><V><M><Y><L><R><N><I><S><A><E><V><E><V><G><K...
May be an adherent factor for rickettsial adsorption to the host-cell surface and a determinant of virulence of individual rickettsial strain. It is the major outer membrane protein.<BOP>
P22940
C4PZQ3
LIAS_SCHMA
Lipoic acid synthase
Schistosoma
<M><G><L><L><L><P><R><G><S><Y><V><F><P><V><L><A><S><V><S><A><A><T><K><R><R><A><E><W><S><Y><I><K><I><N><I><T><H><S><Y><S><S><N><D><K><S><S><E><F><E><E><D><N><P><T><Q><K><L><S><P><E><F><Q><K><A><I><A><H><G><P><S><L><S><E><F><I><K><L><S><N><N><N><Q><S><T><K><E><D><F><F><S><S><P><S><S><V><N><K><S><G><K><S><L><R><L><P><E><W...
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP>
C4PZQ3
A0A1U8QIH0
CICD_EMENI
Cichorine biosynthesis cluster protein D
Aspergillus subgen. Nidulantes
<M><V><G><S><R><H><P><D><Q><C><A><K><R><W><H><H><S><L><D><P><N><V><K><R><G><P><W><T><M><E><E><D><S><S><L><L><E><A><V><Q><K><I><G><R><D><W><K><E><I><G><R><E><L><F><P><S><R><S><T><T><D><I><K><N><R><Y><V><I><L><S><R><R><R><G><P><S><P><A><I><P><E><N><C><S><S><I><D><I><E><T><H><S><S><S><L><A><D><S><K><P><P><I><P><A><E><L><L...
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of cichorine, a phytotoxin active against knapweed, corn, and soybeans.<BOP>
A0A1U8QIH0
Q88M95
COBT_PSEPK
N(1)-alpha-phosphoribosyltransferase
Pseudomonas
<M><T><Q><A><W><W><R><D><A><C><Q><P><L><D><N><A><A><M><D><Q><A><R><A><R><Q><Q><Q><L><T><K><P><A><G><S><L><G><Q><L><E><A><L><A><I><Q><L><A><G><L><Q><G><L><E><R><P><T><L><D><Q><V><A><I><T><I><F><A><G><D><H><G><V><V><E><E><G><I><S><A><Y><P><Q><A><V><T><G><Q><M><L><R><N><F><V><G><G><G><A><A><I><S><V><L><A><R><Q><L><Q><A><S...
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).<BOP>
Q88M95
A8GW74
FOLD_RICB8
Methenyltetrahydrofolate cyclohydrolase
belli group
<M><N><N><V><I><D><G><K><A><L><A><N><E><I><L><S><E><L><K><H><E><V><Q><R><L><K><D><K><T><G><E><S><P><K><L><A><I><V><L><V><G><D><N><P><A><S><I><I><Y><V><K><N><K><I><K><H><A><N><K><I><G><I><D><T><L><L><L><N><L><P><I><T><I><K><T><E><D><L><I><A><K><I><S><E><L><N><L><D><Q><N><V><S><G><I><I><V><Q><L><P><L><P><D><S><I><D><K><N...
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP>
A8GW74
C1A6H2
DNLJ_GEMAT
Polydeoxyribonucleotide synthase [NAD(+)]
Gemmatimonas
<M><T><A><S><S><G><T><P><P><H><Q><T><V><E><R><A><R><E><L><R><E><Q><L><G><T><A><Q><H><E><Y><Y><V><L><D><R><P><T><L><S><D><Q><E><Y><D><R><L><F><R><E><L><Q><G><I><E><A><E><Y><P><T><L><C><T><E><D><S><P><T><R><R><V><G><A><P><V><Q><S><A><F><S><P><H><R><H><L><V><R><M><L><S><L><D><N><A><F><D><L><S><E><L><E><D><F><E><Q><S><L><K...
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP>
C1A6H2
Q03AR1
GUAC_LACP3
Guanosine 5'-monophosphate oxidoreductase
Lacticaseibacillus
<M><N><N><G><M><Q><I><F><D><Y><E><D><I><Q><M><I><P><N><K><C><V><V><Q><S><R><K><E><V><D><T><S><V><K><F><G><P><H><T><F><K><I><P><V><V><P><A><N><M><Q><T><I><I><D><E><P><L><A><I><W><L><A><E><H><D><Y><F><Y><I><M><H><R><F><Q><P><E><R><R><M><D><F><V><R><D><M><K><K><R><G><L><I><A><S><I><S><V><G><V><K><D><D><E><F><D><F><I><E><A...
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.<BOP>
Q03AR1
Q85FH0
NU1C_ADICA
NADH-plastoquinone oxidoreductase subunit 1
Adiantum
<M><I><N><S><T><E><F><C><R><N><K><L><I><H><L><F><D><E><L><E><I><T><M><N><L><S><K><S><I><W><I><F><A><S><T><L><L><L><V><L><G><V><T><M><G><V><L><V><I><V><W><L><E><R><K><V><S><A><G><V><Q><Q><R><I><G><P><E><Y><A><G><P><L><G><I><I><Q><S><L><A><D><G><I><K><L><L><L><K><E><D><I><I><P><A><K><G><N><A><W><L><F><A><A><G><P><A><V><V...
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translo...
Q85FH0
B2J0M4
LEPA_NOSP7
Ribosomal back-translocase LepA
Nostoc
<M><T><D><V><P><A><V><R><I><R><N><F><C><I><I><A><H><I><D><H><G><K><S><T><L><A><D><R><L><L><Q><A><T><G><T><V><E><D><R><K><M><K><E><Q><F><L><D><N><M><D><L><E><R><E><R><G><I><T><I><K><L><Q><A><A><R><M><N><Y><T><A><K><D><G><Q><Q><Y><V><L><N><L><I><D><T><P><G><H><V><D><F><S><Y><E><V><S><R><S><L><V><A><C><E><G><A><L><L><V><V...
Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-t...
B2J0M4
A8ARK8
HLDD_CITK8
ADP-L-glycero-beta-D-manno-heptose-6-epimerase
Citrobacter
<M><I><I><V><T><G><G><A><G><F><I><G><S><N><I><V><K><S><L><N><D><K><G><I><T><D><I><L><V><V><D><N><L><K><D><G><T><K><F><V><N><L><V><D><L><N><I><A><D><Y><M><D><K><E><D><F><L><I><Q><I><M><A><G><E><E><F><G><D><I><E><A><V><F><H><E><G><A><C><S><S><T><T><E><W><D><G><K><Y><M><M><D><N><N><Y><Q><Y><S><K><E><L><L><H><Y><C><L><E><R...
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.<BOP>
A8ARK8
Q2UCB7
MCA1B_ASPOR
Metacaspase-1B
Aspergillus subgen. Circumdati
<M><Y><H><P><N><Y><N><Y><P><P><P><Q><P><G><W><G><G><G><Y><Y><P><P><P><Q><Q><H><Q><Q><Q><Q><Q><W><S><P><P><P><P><Q><P><Y><Y><S><N><G><Y><P><P><P><S><Q><S><P><H><S><Y><S><P><P><Q><Y><P><P><H><G><Q><Y><E><Y><G><H><H><T><P><T><P><P><P><S><S><G><S><Q><Y><R><S><Y><H><S><H><S><P><S><W><G><Q><M><P><P><R><P><P><M><E><A><Q><Q><F...
Involved in cell death (apoptosis).<BOP>
Q2UCB7
Q9Y7M3
PIB2_SCHPO
Glutamine sensor pib2
Schizosaccharomyces
<M><T><T><V><H><Q><L><S><G><H><G><P><L><S><R><L><N><I><Y><S><G><A><S><P><Y><T><Q><R><V><R><P><S><Y><E><L><I><E><A><P><T><R><Q><A><T><N><G><T><G><S><V><S><G><S><P><N><S><S><S><N><S><T><P><A><N><Q><G><S><L><P><S><H><T><N><P><Q><L><Y><S><S><I><T><R><K><E><R><P><E><L><F><R><S><Y><S><G><N><P><R><L><S><K><P><Y><A><S><S><K><L...
Functions as an intracellular glutamine sensor that directly activates the TORC1 signaling pathway, to promote cell growth when glutamine is available.<BOP>
Q9Y7M3
O07015
RSBQ_BACSU
Sigma factor SigB regulation protein RsbQ
Bacillus
<M><N><E><A><I><L><S><R><N><H><V><K><V><K><G><S><G><K><A><S><I><M><F><A><P><G><F><G><C><D><Q><S><V><W><N><A><V><A><P><A><F><E><E><D><H><R><V><I><L><F><D><Y><V><G><S><G><H><S><D><L><R><A><Y><D><L><N><R><Y><Q><T><L><D><G><Y><A><Q><D><V><L><D><V><C><E><A><L><D><L><K><E><T><V><F><V><G><H><S><V><G><A><L><I><G><M><L><A><S><I...
Positive regulator required for energy stress activation of the sigma-B transcription factor. Could be required for RsbP phosphatase activity.<BOP>
O07015
A3CQU5
PURA_STRSV
IMP--aspartate ligase
Streptococcus
<M><T><S><V><V><V><V><G><T><Q><W><G><D><E><G><K><G><K><I><T><D><F><L><S><A><N><A><E><V><I><A><R><Y><Q><G><G><D><N><A><G><H><T><I><V><I><D><G><K><K><Y><K><L><H><L><I><P><S><G><I><F><F><P><E><K><I><S><V><I><G><N><G><M><V><V><N><P><K><S><L><V><K><E><L><N><Y><L><H><E><E><G><V><T><T><D><N><L><R><I><S><D><R><A><H><V><I><L><P...
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP>
A3CQU5
A1R1C6
UREE_PAEAT
Urease accessory protein UreE
Paenarthrobacter
<M><I><I><E><K><I><L><G><N><L><H><Q><Q><P><D><A><Y><A><S><H><H><K><E><K><V><V><L><P><S><T><L><L><V><K><R><I><Q><R><V><T><T><D><H><G><K><E><L><G><I><R><L><P><A><G><T><G><D><L><R><D><G><D><I><L><A><I><D><Q><H><N><I><I><V><V><S><V><L><P><T><D><V><L><V><I><K><A><R><T><I><H><E><M><G><V><V><A><H><S><L><G><N><R><H><L><Q><A><Q...
Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.<BOP>
A1R1C6
Q4WLM9
TPS1A_ASPFU
UDP-glucose-glucosephosphate glucosyltransferase
Aspergillus subgen. Fumigati
<M><P><S><L><E><N><S><T><Q><N><E><A><R><L><L><L><V><S><N><R><L><P><I><T><I><K><R><S><E><D><G><K><Y><D><F><S><M><S><S><G><G><L><V><S><G><L><S><G><L><S><K><S><T><T><F><Q><W><Y><G><W><P><G><L><E><V><P><E><E><E><I><P><V><V><K><Q><R><L><K><D><E><Y><G><A><I><P><V><F><I><D><D><E><L><A><D><R><H><Y><N><G><F><S><N><S><I><L><W><P...
Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process . The disaccharide trehalose serves as a storage carbohydrate that is mobilized during conidial germination . Regulates the level of trehalose as...
Q4WLM9
Q8NZ45
HUTG_STRP8
Formiminoglutamate hydrolase
Streptococcus
<M><L><E><D><Y><Y><P><S><T><T><S><Y><Y><H><G><G><I><D><D><D><L><Y><T><A><K><W><G><M><V><M><T><F><L><D><L><N><D><S><S><L><T><P><F><E><G><T><H><F><A><L><I><G><F><K><S><D><K><G><V><Y><I><N><N><G><R><V><G><A><V><E><S><P><A><A><I><R><T><Q><L><A><K><F><P><W><H><L><G><N><Q><V><M><V><Y><D><V><G><N><I><D><G><P><N><R><S><L><E><Q...
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.<BOP>
Q8NZ45
Q8LNW4
FLOT2_ORYSJ
Nodulin-like protein 2
Oryza sativa
<M><A><R><F><V><V><A><G><P><S><E><Y><L><A><I><T><G><W><G><I><D><D><V><K><L><A><K><K><A><W><V><F><A><G><Q><K><C><S><R><F><D><I><S><P><V><N><Y><E><F><N><V><E><A><M><S><S><E><K><L><A><F><N><L><P><A><V><F><T><I><G><P><K><I><T><P><A><P><A><P><E><V><D><G><A><S><N><Q><R><R><V><L><M><P><E><S><E><E><K><L><L><L><Y><A><K><L><I><A...
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.<BOP>
Q8LNW4
Q9HA65
TBC17_HUMAN
TBC1 domain family member 17
Homo
<M><E><G><A><G><Y><R><V><V><F><E><K><G><G><V><Y><L><H><T><S><A><K><K><Y><Q><D><R><D><S><L><I><A><G><V><I><R><V><V><E><K><D><N><D><V><L><L><H><W><A><P><V><E><E><A><G><D><S><T><Q><I><L><F><S><K><K><D><S><S><G><G><D><S><C><A><S><E><E><E><P><T><F><D><P><G><Y><E><P><D><W><A><V><I><S><T><V><R><P><Q><L><C><H><S><E><P><T><R><G...
Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy...
Q9HA65
Q21EF2
PYRE_SACD2
Orotate phosphoribosyltransferase
Saccharophagus
<M><Q><A><Y><Q><K><D><F><I><Q><L><A><L><K><A><Q><A><L><K><F><G><E><F><T><L><K><S><G><R><V><S><P><Y><F><F><N><A><G><Q><F><Q><T><G><S><A><L><A><S><L><G><R><F><Y><A><Q><A><L><V><D><A><G><V><E><F><D><M><I><F><G><P><A><Y><K><G><I><P><L><A><T><T><T><A><T><A><L><A><D><H><H><Q><K><D><M><P><F><A><Y><N><R><K><E><V><K><A><H><G><E...
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).<BOP>
Q21EF2
Q87SF9
LPXC_VIBPA
UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase
Vibrio
<M><I><R><Q><R><T><L><K><E><I><V><K><T><T><G><V><G><L><H><S><G><R><K><V><T><L><T><L><R><P><A><A><A><N><T><G><I><I><Y><R><R><T><D><V><N><P><P><V><D><F><P><A><D><P><A><S><V><R><D><T><M><L><C><T><A><L><V><N><D><E><G><V><R><I><S><T><V><E><H><L><N><A><A><L><A><G><M><G><I><D><N><I><I><V><E><V><D><A><P><E><I><P><I><M><D><G><S...
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.<BOP>
Q87SF9
Q53T59
H1BP3_HUMAN
HS1-binding protein 3
Homo
<M><Q><S><P><A><V><L><V><T><S><R><R><L><Q><N><A><H><T><G><L><D><L><T><V><P><Q><H><Q><E><V><R><G><K><M><M><S><G><H><V><E><Y><Q><I><L><V><V><T><R><L><A><A><F><K><S><A><K><H><R><P><E><D><V><V><Q><F><L><V><S><K><K><Y><S><E><I><E><E><F><Y><Q><K><L><S><S><R><Y><A><A><A><S><L><P><P><L><P><R><K><V><L><F><V><G><E><S><D><I><R><E...
May be a modulator of IL-2 signaling.<BOP>
Q53T59
Q5AU92
AGALC_EMENI
Melibiase C
Aspergillus subgen. Nidulantes
<M><F><R><S><T><A><T><V><A><A><A><T><A><M><G><L><L><T><A><T><G><H><G><S><L><A><I><A><Q><G><T><T><G><S><N><A><V><V><V><D><G><T><N><F><A><L><N><G><A><S><M><S><Y><V><F><H><A><N><S><T><T><G><D><L><V><S><D><H><F><G><A><T><I><S><G><A><I><P><A><P><K><E><P><A><V><N><G><W><V><G><M><P><G><R><I><R><R><E><F><P><D><Q><G><R><G><D><F...
Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides. Active on paranitrophenyl-alpha-galactoside, raffinose, locust bean gum and gum guar.<BOP>
Q5AU92
B7LEY2
FUCI_ECO55
FucIase
Escherichia
<M><K><K><I><S><L><P><K><I><G><I><R><P><V><I><D><G><R><R><M><G><V><R><E><S><L><E><E><Q><T><M><N><M><A><K><A><T><A><A><L><L><T><E><K><L><R><H><A><C><G><A><A><V><E><C><V><I><S><D><T><C><I><A><G><M><A><E><A><A><A><C><E><E><K><F><S><S><Q><N><V><G><L><T><I><T><V><T><P><C><W><C><Y><G><S><E><T><I><D><M><D><P><T><R><P><K><A><I...
Converts the aldose L-fucose into the corresponding ketose L-fuculose.<BOP>
B7LEY2
Q2IV75
GUAA_RHOP2
Glutamine amidotransferase
Rhodopseudomonas
<M><T><A><P><S><T><P><S><A><S><S><V><V><P><S><G><A><D><T><S><P><H><V><A><A><I><H><E><K><I><L><I><V><D><F><G><S><Q><V><T><Q><L><I><A><R><R><V><R><E><E><G><V><Y><S><E><I><V><P><F><Q><K><A><E><A><A><F><A><E><M><K><P><K><A><V><I><L><S><G><G><P><A><S><V><L><D><A><D><A><P><A><A><P><M><A><I><L><E><A><G><V><P><V><L><G><I><C><Y...
Catalyzes the synthesis of GMP from XMP.<BOP>
Q2IV75
P21841
PSPC_MOUSE
SP5
Mus
<M><D><M><S><S><K><E><V><L><M><E><S><P><P><D><Y><S><A><G><P><R><S><Q><F><R><I><P><C><C><P><V><H><L><K><R><L><L><I><V><V><V><V><V><V><L><V><V><V><V><I><V><G><A><L><L><M><G><L><H><M><S><Q><K><H><T><E><M><V><L><E><M><S><I><G><A><P><E><T><Q><K><R><L><A><P><S><E><R><A><D><T><I><A><T><F><S><I><G><S><T><G><I><V><V><Y><D><Y><Q...
Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.<BOP>
P21841
Q5HPC6
ODO1_STAEQ
Alpha-ketoglutarate dehydrogenase
Staphylococcus
<M><T><K><N><K><K><E><F><T><E><A><P><V><N><F><G><A><N><L><G><L><M><L><D><L><Y><D><D><Y><L><Q><D><P><S><S><V><P><E><D><L><Q><V><L><F><S><T><I><K><T><G><E><A><H><I><E><A><K><P><T><T><D><G><G><G><S><Q><A><G><D><S><T><I><K><R><V><M><R><L><I><D><N><I><R><Q><Y><G><H><L><K><A><D><I><Y><P><V><N><P><P><E><R><Q><N><V><P><K><L><E...
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).<BOP>
Q5HPC6
Q9VRX2
VPS8_DROME
Vacuolar protein sorting 8
Sophophora
<M><S><E><L><K><A><P><S><L><Q><S><L><L><E><S><E><R><G><S><T><D><S><L><L><A><E><S><L><Q><L><D><F><E><D><L><D><D><A><E><F><A><I><P><P><T><D><V><L><P><T><L><E><A><V><L><S><E><F><E><A><D><S><D><V><A><S><E><F><G><M><P><V><P><H><A><T><P><T><P><S><I><G><E><D><S><T><I><R><T><D><G><R><G><G><G><G><S><I><M><R><Y><T><L><L><H><G><I...
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes probably as part of the class C core vacuole/endosome tethering (CORVET) complex. Specifically required for endocytic trafficking in a subset of cells, such as hemocytes an...
Q9VRX2
Q43714
DCS3_GOSAR
(+)-delta-cadinene synthase isozyme A
Gossypium
<M><A><S><Q><A><S><Q><V><L><A><S><P><H><P><A><I><S><S><E><N><R><P><K><A><D><F><H><P><G><I><W><G><D><M><F><I><I><C><P><D><T><D><I><D><A><A><T><E><L><Q><Y><E><E><L><K><A><Q><V><R><K><M><I><M><E><P><V><D><D><S><N><Q><K><L><P><F><I><D><A><V><Q><R><L><G><V><S><Y><H><F><E><K><E><I><E><D><E><L><E><N><I><Y><R><D><T><N><N><N><D...
Responsible for the cyclization of trans,trans-farnesyl diphosphate (FPP) to (+)-delta cadinene.<BOP>
Q43714
Q20Z46
NUOI2_RHOPB
NDH-1 subunit I 2
Rhodopseudomonas
<M><I><G><W><L><E><A><L><L><R><V><G><R><K><L><A><A><K><T><V><T><V><Q><Y><P><E><V><K><P><Q><L><P><P><R><S><R><G><R><I><V><L><T><R><D><P><D><G><Q><E><R><C><V><A><C><N><L><C><A><V><A><C><P><V><G><C><I><D><L><S><K><A><V><A><E><D><G><R><W><Y><P><E><H><F><R><I><N><F><A><R><C><I><F><C><G><Y><C><E><E><A><C><P><T><A><A><I><Q><L...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
Q20Z46
P42636
TPM1_BIOGL
Tropomyosin I
Biomphalaria
<M><D><A><I><K><K><K><M><L><A><M><K><M><E><K><E><N><A><I><D><R><A><E><Q><M><E><Q><K><L><R><D><V><E><E><T><K><N><K><L><E><E><E><F><N><N><L><Q><N><K><F><S><N><L><Q><N><D><F><D><T><A><N><E><G><L><T><E><A><Q><T><K><L><E><A><S><E><K><H><V><A><E><L><E><S><D><T><A><G><L><N><R><R><I><Q><L><L><E><E><D><L><E><R><S><E><E><R><L><Q...
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.<BOP>
P42636
Q5VWK5
IL23R_HUMAN
Interleukin-23 receptor
Homo
<M><N><Q><V><T><I><Q><W><D><A><V><I><A><L><Y><I><L><F><S><W><C><H><G><G><I><T><N><I><N><C><S><G><H><I><W><V><E><P><A><T><I><F><K><M><G><M><N><I><S><I><Y><C><Q><A><A><I><K><N><C><Q><P><R><K><L><H><F><Y><K><N><G><I><K><E><R><F><Q><I><T><R><I><N><K><T><T><A><R><L><W><Y><K><N><F><L><E><P><H><A><S><M><Y><C><T><A><E><C><P><K...
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infectio...
Q5VWK5
B1AJD7
RS4_UREP2
30S ribosomal protein S4
Ureaplasma
<M><S><R><Y><T><G><S><I><Y><K><K><S><R><R><L><G><F><S><L><L><E><N><N><K><E><F><N><S><G><K><K><R><T><Y><G><P><G><Q><H><G><N><K><K><V><K><L><S><N><Y><G><Q><Q><L><V><E><K><Q><K><L><M><F><L><Y><G><L><N><D><R><Q><F><R><R><L><Y><R><V><A><L><G><R><P><G><V><L><T><L><N><L><L><Q><V><L><E><S><R><L><D><S><L><V><Y><R><A><G><F><A><P...
With S5 and S12 plays an important role in translational accuracy.<BOP>
B1AJD7
Q9ZL09
DER_HELPJ
GTP-binding protein EngA
Helicobacter
<M><N><T><S><H><K><T><L><K><T><I><A><I><L><G><Q><P><N><V><G><K><S><S><L><F><N><R><L><A><R><E><R><I><A><I><T><S><D><F><A><G><T><T><R><D><I><N><K><R><K><I><A><L><N><G><H><E><V><E><L><L><D><T><G><G><M><A><K><D><A><L><L><S><K><E><I><K><A><L><N><L><K><A><A><Q><M><S><D><L><I><L><Y><V><V><D><G><K><S><I><P><S><D><E><D><L><K><L...
GTPase that plays an essential role in the late steps of ribosome biogenesis.<BOP>
Q9ZL09
A5UUP4
LEUD_ROSS1
Isopropylmalate isomerase
Roseiflexus
<M><Q><P><I><S><V><I><T><G><R><I><V><A><L><P><V><Q><D><I><D><T><D><Q><I><I><P><A><R><Y><L><K><V><T><D><K><S><G><L><A><E><G><L><F><Y><A><W><R><F><D><A><D><G><K><P><N><P><D><F><V><L><N><R><P><E><T><Q><G><A><T><I><L><V><A><G><R><N><F><G><C><G><S><S><R><E><H><A><P><W><A><L><L><G><Y><G><F><K><A><V><I><S><P><Y><F><A><D><I><F...
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.<BOP>
A5UUP4
C5CGH6
RS11_KOSOT
30S ribosomal protein S11
Kosmotoga
<M><A><R><N><R><S><S><R><T><K><K><R><K><K><L><N><I><D><R><G><V><V><H><I><K><S><T><F><N><N><T><I><I><T><L><S><D><L><D><G><N><T><I><L><W><A><S><G><G><T><V><G><Y><S><G><S><K><K><S><T><P><Y><A><A><Q><L><A><A><D><K><I><A><K><E><A><L><K><L><G><L><T><R><V><S><I><E><V><K><G><P><G><A><G><R><E><A><A><I><R><T><I><Q><A><A><G><L><V...
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.<BOP>
C5CGH6