accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
Q0USG2
CIAO1_PHANO
Probable cytosolic iron-sulfur protein assembly protein 1
Parastagonospora
<M><S><D><P><R><P><N><T><L><S><P><L><A><T><L><T><P><P><S><S><S><R><T><W><Q><T><A><P><H><P><T><L><P><I><V><A><T><A><C><S><D><R><S><V><R><V><Y><S><L><T><S><F><T><L><L><H><S><I><T><G><G><H><K><R><S><V><R><A><V><S><W><K><P><H><T><Q><G><Q><S><V><L><A><T><G><S><F><D><S><S><A><G><I><W><R><R><E><E><Q><G><G><N><E><D><D><F><T><N...
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.<BOP>
Q0USG2
C8ZCV7
SDC25_YEAS8
Guanine nucleotide exchange factor SDC25
Saccharomyces
<M><S><R><T><A><S><Y><A><G><M><T><T><P><V><K><D><K><E><G><H><G><I><P><C><L><Q><P><I><D><V><V><E><C><T><Y><Q><Y><F><T><K><S><Q><N><K><L><S><L><R><V><G><D><L><I><Y><V><L><T><K><G><S><N><G><W><W><D><G><V><L><I><R><H><S><A><N><N><N><N><N><S><L><I><L><D><R><G><W><F><P><P><S><F><T><R><S><I><L><N><E><L><H><G><V><P><E><I><G><N...
Promotes the exchange of Ras-bound GDP by GTP.<BOP>
C8ZCV7
O32481
GRPE_LEGPN
HSP-70 cofactor
Legionella
<M><S><K><Q><N><K><K><D><W><K><K><F><K><D><E><H><K><E><E><H><K><V><E><N><E><I><L><E><E><E><T><D><E><E><S><Q><H><Q><E><P><A><L><G><H><P><S><Y><T><A><L><E><E><Q><L><T><L><A><E><Q><K><A><H><E><N><W><E><K><S><V><R><A><L><A><E><L><E><N><V><R><R><R><M><E><R><E><V><A><N><A><H><K><Y><G><V><E><K><L><I><S><A><L><L><P><V><V><D><S...
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-b...
O32481
Q9CKK4
TRUD_PASMU
tRNA-uridine isomerase D
Pasteurella
<M><E><L><A><Y><L><H><T><R><P><E><Q><Y><A><R><L><K><A><E><C><A><D><F><I><V><K><E><N><L><G><Y><E><M><S><G><D><G><E><F><V><A><V><K><V><R><K><T><D><C><N><T><L><F><V><G><E><K><L><A><Q><F><V><G><I><S><E><R><N><M><G><Y><A><G><L><K><D><R><K><A><V><T><E><Q><W><F><C><L><H><M><P><G><Q><P><T><P><D><F><R><S><F><Q><L><E><G><V><D><I...
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.<BOP>
Q9CKK4
B9E8D6
THIM_MACCJ
4-methyl-5-beta-hydroxyethylthiazole kinase
Macrococcus
<M><V><K><L><N><Q><L><R><K><D><N><P><L><I><I><C><I><T><N><D><V><V><K><N><F><T><A><N><G><L><L><A><L><G><A><S><P><A><M><A><T><E><R><Q><E><M><D><E><F><L><A><H><A><G><A><L><L><I><N><I><G><S><I><E><E><G><D><K><E><N><M><L><Q><A><A><A><F><A><N><K><H><H><V><P><I><V><L><D><P><V><A><C><G><A><S><K><F><R><K><D><F><C><L><R><L><L><N...
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP>
B9E8D6
A8SED8
IF1C_CERDE
Translation initiation factor IF-1, chloroplastic
Ceratophyllum
<M><K><E><Q><K><L><I><H><E><G><L><I><T><E><S><L><P><N><G><M><F><R><V><R><L><D><N><E><K><M><I><L><G><Y><V><S><G><R><I><R><R><S><F><I><R><I><L><P><G><D><R><V><K><I><E><V><S><R><Y><D><S><T><R><G><R><I><I><Y><R><L><R><N><K><D><S><N><D>
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-...
A8SED8
A4J6A4
RISB_DESRM
6,7-dimethyl-8-ribityllumazine synthase
Desulforamulus
<M><P><K><V><F><E><G><H><L><L><G><Q><E><L><K><F><G><I><V><V><G><R><F><N><E><F><I><T><N><K><L><L><S><G><A><L><D><A><L><K><R><H><G><V><E><D><E><N><V><E><I><A><Y><V><P><G><A><Y><E><I><P><L><V><A><K><K><M><A><D><S><K><R><Y><D><G><V><I><C><L><G><A><V><I><R><G><A><T><P><H><F><E><Y><V><S><A><E><V><S><K><G><V><A><K><I><S><L><D...
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<BOP>
A4J6A4
P23154
CYPC_STRCO
WhiE ORF VI
Streptomyces albidoflavus group
<M><A><G><H><T><D><N><E><I><T><I><A><A><P><M><E><L><V><W><N><M><T><N><D><I><E><K><W><P><G><L><F><S><E><Y><A><S><V><E><V><L><G><R><D><D><D><K><V><T><F><R><L><T><M><H><P><D><A><D><G><K><V><W><S><W><V><S><E><R><V><A><D><P><V><T><R><T><V><R><A><Q><R><V><E><T><G><P><F><Q><Y><M><N><I><V><W><E><Y><A><E><T><A><E><G><T><V><M><R...
Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces coelicolor.<BOP>
P23154
Q759K3
PALB_ASHGO
Cysteine protease RIM13
Eremothecium
<M><E><A><L><L><A><V><E><E><T><G><N><D><L><W><K><E><L><K><E><L><Y><W><A><Q><Y><V><Q><N><S><V><D><K><V><Q><F><E><R><Y><V><R><K><V><K><S><A><D><D><Y><W><L><V><R><A><L><L><A><F><S><D><S><R><K><A><C><T><F><N><S><R><F><E><W><L><T><M><Q><A><H><G><R><Q><Y><P><P><L><A><S><K><D><A><G><K><L><I><W><N><A><R><R><E><F><R><Y><A><E><P...
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.<BOP>
Q759K3
Q834T4
DER_ENTFA
GTP-binding protein EngA
Enterococcus
<M><A><N><P><T><I><A><I><V><G><R><P><N><V><G><K><S><T><I><F><N><R><I><A><G><V><R><I><S><I><V><E><D><T><P><G><V><T><R><D><R><I><Y><T><T><G><E><W><L><G><R><E><F><S><I><I><D><T><G><G><I><D><L><G><D><E><P><F><M><D><Q><I><K><H><Q><A><E><I><A><I><D><E><A><D><V><I><I><F><V><A><S><G><R><E><G><I><T><D><A><D><E><L><V><A><K><I><L...
GTPase that plays an essential role in the late steps of ribosome biogenesis.<BOP>
Q834T4
P0CR09
SPB4_CRYNB
ATP-dependent rRNA helicase SPB4
Cryptococcus neoformans species complex
<M><D><A><P><V><P><A><A><P><A><F><G><G><S><W><A><K><L><N><P><P><L><S><P><W><I><L><D><V><I><N><S><M><G><F><K><N><M><T><P><V><Q><A><G><T><I><P><R><A><V><K><N><Q><D><C><V><V><E><A><V><T><G><S><G><K><T><L><A><F><T><I><P><V><L><E><R><L><S><R><R><E><E><P><Y><K><K><G><E><I><A><A><I><V><V><A><P><T><R><E><L><A><T><Q><I><H><A><V...
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal fo...
P0CR09
C0MCT3
PRSA_STRS7
Foldase protein PrsA
Streptococcus
<M><K><K><S><T><K><L><L><A><G><I><V><T><L><A><S><A><M><T><L><A><A><C><Q><S><T><N><D><N><T><S><V><I><T><M><K><G><D><T><I><S><V><S><D><F><Y><N><E><T><K><N><T><E><V><S><Q><R><A><M><L><N><L><V><V><S><R><V><F><E><D><Q><Y><G><K><K><V><S><K><K><K><T><E><E><A><Y><N><K><S><A><E><Q><Y><G><A><S><F><S><A><A><L><A><Q><S><G><L><T><T...
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.<BOP>
C0MCT3
B7NMA8
CDD_ECO7I
Cytidine aminohydrolase
Escherichia
<M><H><P><R><F><Q><T><A><F><A><Q><L><A><D><N><L><Q><S><A><L><E><P><I><L><A><D><K><Y><F><P><A><L><L><T><G><E><Q><V><S><S><L><K><S><A><T><G><L><D><E><D><A><L><A><F><A><L><L><P><L><A><A><A><C><A><R><T><P><L><S><N><F><N><V><G><A><I><A><R><G><V><S><G><T><W><Y><F><G><A><N><M><E><F><I><G><A><T><M><Q><Q><T><V><H><A><E><Q><S><A...
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.<BOP>
B7NMA8
A5EW90
RECA_DICNV
Recombinase A
Dichelobacter
<M><N><E><E><Q><K><K><A><L><T><A><V><L><T><Q><L><D><K><Q><F><G><K><G><T><V><M><R><L><G><E><Q><V><A><A><H><D><I><Q><A><I><S><T><G><S><L><T><L><D><I><A><L><G><I><G><G><L><P><K><G><R><I><V><E><I><Y><G><P><E><S><S><G><K><T><T><M><M><L><H><V><I><A><E><A><Q><K><N><G><G><T><A><A><F><I><D><A><E><H><A><L><D><P><I><Y><A><R><K><L...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
A5EW90
A6VDH0
RL31_PSEA7
50S ribosomal protein L31
Pseudomonas
<M><K><A><D><I><H><P><A><Y><E><A><I><E><A><T><C><S><C><G><N><V><I><K><T><R><S><T><L><C><K><P><I><H><L><D><V><C><S><E><C><H><P><F><Y><T><G><K><Q><K><V><L><D><T><G><G><R><I><D><R><F><K><Q><R><F><G><V><F><G><A><T><K>
Binds the 23S rRNA.<BOP>
A6VDH0
P93740
NUD23_ARATH
FAD diphosphatase
Arabidopsis
<M><L><K><A><V><Q><I><L><G><W><S><S><G><L><T><I><S><Q><R><L><T><K><T><R><K><S><S><T><V><S><F><I><S><S><S><L><N><L><S><S><V><T><S><S><S><P><R><R><I><F><S><F><K><P><T><R><M><S><S><S><L><P><G><S><D><P><V><A><N><S><P><T><F><V><S><V><Q><S><A><G><D><V><R><K><I><K><F><C><Q><W><C><G><G><P><T><K><H><E><I><P><D><G><E><E><K><L><R...
Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can use FAD and ADP-ribose as substrates.<BOP>
P93740
Q82T75
RPOB_NITEU
Transcriptase subunit beta
Nitrosomonas
<M><S><Y><S><F><A><E><K><K><R><I><R><K><S><F><A><K><R><A><S><I><L><P><F><P><F><L><L><A><T><Q><I><Q><S><Y><T><D><F><L><Q><A><E><I><A><P><G><K><R><K><N><Q><G><L><Q><A><A><F><N><S><V><F><P><I><E><S><H><S><N><N><A><R><L><D><F><I><S><Y><M><L><G><S><P><V><F><D><V><K><E><C><Q><Q><R><G><L><T><Y><A><A><P><L><R><A><R><V><R><L><T...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
Q82T75
Q9RT27
ACP_DEIRA
Acyl carrier protein
Deinococcus
<M><A><T><F><D><D><V><K><D><V><I><V><D><K><L><G><V><D><E><G><K><V><T><P><E><A><R><F><V><E><D><L><G><A><D><S><L><E><T><V><E><L><I><M><G><L><E><D><K><F><G><V><T><I><P><D><E><A><A><E><T><I><R><T><V><Q><A><A><V><D><Y><I><D><N><N><Q>
Carrier of the growing fatty acid chain in fatty acid biosynthesis.<BOP>
Q9RT27
Q8G487
DEF2_BIFLO
Polypeptide deformylase 2
Bifidobacterium
<M><A><I><R><E><I><R><V><V><P><D><P><V><L><R><T><P><C><D><E><I><K><E><I><T><P><A><V><R><R><L><V><D><D><L><L><E><T><V><D><D><P><G><R><A><G><L><S><A><N><Q><I><G><V><S><L><R><A><F><S><Y><N><I><D><G><K><V><G><Y><V><L><N><P><V><L><E><E><K><S><G><E><Q><Y><G><D><E><G><C><L><S><V><P><G><L><W><Y><K><T><R><R><A><D><Y><A><R><V><R...
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.<BOP>
Q8G487
O59248
RNP4_PYRHO
Rpp21
Pyrococcus
<M><V><D><I><V><K><R><R><D><W><E><K><K><E><K><K><K><I><A><I><E><R><I><D><T><L><F><T><L><A><E><R><V><A><R><Y><S><P><D><L><A><K><R><Y><V><E><L><A><L><E><I><Q><K><K><A><K><V><K><I><P><R><K><W><K><R><R><Y><C><K><R><C><H><T><F><L><I><P><G><V><N><A><R><V><R><L><R><T><K><R><M><P><H><V><V><I><T><C><L><E><C><G><Y><I><M><R><Y><P...
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Binds RNase P RNA.<BOP>
O59248
Q1PDI1
TET15_ARATH
Tetraspanin-15
Arabidopsis
<M><A><D><N><A><Q><V><V><P><V><E><E><P><A><A><T><A><T><A><T><A><T><A><T><A><T><T><E><P><E><A><K><S><S><D><Q><M><E><S><Q><S><D><N><K><P><P><M><G><T><L><M><A><L><V><N><I><L><A><A><G><V><L><P><I><F><T><F><V><L><S><L><T><L><L><G><Y><A><V><W><L><L><Y><M><R><S><Y><D><C><E><D><I><L><G><L><P><R><V><Q><T><L><A><S><V><G><L><L><A...
May be involved in the regulation of cell differentiation.<BOP>
Q1PDI1
Q98N51
RS3_RHILO
30S ribosomal protein S3
Mesorhizobium
<M><G><Q><K><V><N><P><I><G><L><R><L><G><I><N><R><T><W><D><S><R><W><F><A><N><T><G><E><Y><G><K><L><L><H><E><D><I><K><I><R><K><Y><L><E><K><E><L><K><Q><A><A><I><S><K><V><V><I><E><R><P><H><K><K><C><R><V><T><I><H><A><A><R><P><G><L><I><I><G><K><K><G><A><D><I><E><K><L><R><K><K><L><M><E><M><T><K><S><E><T><H><L><N><I><V><E><V><R...
Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.<BOP>
Q98N51
Q0K959
RLMN_CUPNH
tRNA m2A37 methyltransferase
Cupriavidus
<M><N><A><L><V><N><L><L><D><L><D><A><D><A><L><T><A><Y><C><G><E><L><G><E><K><P><F><R><A><R><Q><L><Q><R><W><I><H><H><Y><G><A><S><R><F><D><A><M><S><D><L><A><K><S><L><R><E><K><L><A><T><R><A><E><I><R><A><P><A><A><I><T><D><H><L><S><A><D><G><T><R><K><W><L><L><D><V><G><Q><G><N><A><V><E><T><V><Y><I><P><E><E><T><R><G><T><L><C><V...
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.<BOP>
Q0K959
P81816
ALL13_CARMA
Carcinustatin-13
Carcinus
<E><Y><D><D><M><Y><T><E><K><R><P><K><V><Y><A><F><G><L>
May act as a neurotransmitter or neuromodulator.<BOP>
P81816
Q7V9Y5
RPOA_PROMA
Transcriptase subunit alpha
Prochlorococcus
<M><L><Q><Y><Q><I><D><R><I><E><H><Q><V><S><D><D><R><S><Q><T><G><I><F><L><I><G><P><L><E><R><G><Q><A><T><T><L><G><N><S><L><R><R><V><L><M><G><G><L><E><G><S><A><V><T><A><V><R><I><S><G><V><N><H><E><Y><A><T><V><P><G><V><R><E><D><V><L><D><I><L><L><N><C><K><E><L><T><V><N><S><R><S><Q><E><L><E><I><G><R><L><V><V><T><G><P><A><E><V...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
Q7V9Y5
Q21K22
SYS_SACD2
Seryl-tRNA(Ser/Sec) synthetase
Saccharophagus
<M><L><D><P><K><L><L><R><N><Q><L><N><D><V><A><E><N><L><K><K><R><G><Y><E><L><D><T><Q><A><F><T><A><L><E><E><R><R><R><T><L><Q><T><A><C><E><S><L><Q><Q><E><R><N><T><R><S><K><N><I><G><K><A><K><A><A><G><E><D><I><G><P><L><L><Q><E><V><D><N><L><K><S><A><L><A><E><A><E><Q><N><L><Q><A><L><Q><G><E><L><E><A><L><V><S><A><I><P><N><M><V...
Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).<BOP>
Q21K22
Q4CY36
MTNA1_TRYCC
Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein 1
Schizotrypanum
<M><T><R><A><H><N><A><T><L><E><S><I><Q><Y><A><R><G><T><L><R><L><L><D><Q><R><K><L><P><F><E><T><V><F><D><E><I><L><T><V><D><D><I><W><T><A><I><K><E><M><R><V><R><G><A><P><A><I><A><V><S><A><A><L><A><I><A><V><A><A><G><N><E><L><K><K><N><D><G><A><C><N><S><V><D><G><T><R><R><F><L><L><E><S><C><D><T><V><M><T><A><R><P><T><A><V><N><L...
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).<BOP>
Q4CY36
P49281
NRAM2_HUMAN
Solute carrier family 11 member 2
Homo
<M><V><L><G><P><E><Q><K><M><S><D><D><S><V><S><G><D><H><G><E><S><A><S><L><G><N><I><N><P><A><Y><S><N><P><S><L><S><Q><S><P><G><D><S><E><E><Y><F><A><T><Y><F><N><E><K><I><S><I><P><E><E><E><Y><S><C><F><S><F><R><K><L><W><A><F><T><G><P><G><F><L><M><S><I><A><Y><L><D><P><G><N><I><E><S><D><L><Q><S><G><A><V><A><G><F><K><L><L><W><I...
Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic...
P49281
B0TIV7
RNC_SHEHH
Ribonuclease III
Shewanella
<M><E><P><I><K><N><I><P><R><L><C><R><T><L><G><Y><E><F><T><E><Q><A><F><L><D><Q><A><L><T><H><R><S><A><S><N><K><H><N><E><R><L><E><F><L><G><D><S><I><L><S><I><V><I><S><D><A><L><Y><H><Q><F><P><T><A><T><E><G><D><L><S><R><M><R><A><T><L><V><C><G><K><M><L><A><E><I><A><I><E><F><K><L><G><D><Y><L><K><L><G><P><G><E><L><K><S><G><G><F...
Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.<B...
B0TIV7
Q7NZH8
NUOD_CHRVO
NDH-1 subunit D
Chromobacterium
<M><A><E><I><R><N><Y><T><L><N><F><G><P><Q><H><P><A><A><H><G><V><L><R><L><V><L><E><L><D><G><E><V><V><Q><R><A><D><P><H><I><G><L><L><H><R><G><T><E><K><L><A><E><S><K><T><F><I><Q><S><L><P><Y><M><D><R><L><D><Y><V><S><M><M><C><N><E><H><A><Y><C><L><A><I><E><K><M><M><G><I><E><V><P><E><R><A><Q><Y><I><R><V><M><F><A><E><I><T><R><I...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t...
Q7NZH8
P94535
GLCD_BACSU
Glycolate dehydrogenase subunit GlcD
Bacillus
<M><I><T><K><D><V><K><E><Q><L><I><Q><V><S><G><P><E><N><F><D><D><S><N><A><G><R><L><V><Y><S><Y><D><A><T><P><Q><Y><Q><S><M><P><D><A><V><I><A><P><R><N><T><D><E><I><S><R><I><L><T><I><C><S><E><H><R><V><P><I><V><P><R><G><S><G><T><N><L><C><G><G><T><C><P><T><E><G><G><L><V><L><L><F><K><H><M><N><Q><I><L><E><I><D><E><E><N><L><T><A...
Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is also able to oxidize D-lactate ((R)-lactate). Does not link directly to O(2), and 2,6-dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that funct...
P94535
P63952
HISX_STAAM
Histidinol dehydrogenase
Staphylococcus
<M><L><N><A><Q><Q><F><L><N><Q><F><S><L><E><A><P><L><D><E><S><L><Y><P><I><I><R><D><I><C><Q><E><V><K><V><H><G><D><K><A><L><K><M><Y><N><L><T><F><D><H><T><K><T><D><H><L><E><I><S><H><E><Q><I><K><A><A><F><D><T><L><D><E><K><T><K><Q><A><L><Q><Q><S><Y><E><R><I><K><A><Y><Q><E><S><I><K><Q><T><N><Q><Q><L><E><E><S><V><E><C><Y><E><I...
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.<BOP>
P63952
Q2JI25
TSAD_SYNJB
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
unclassified Synechococcus
<M><P><R><V><L><A><I><E><T><S><C><D><E><T><A><V><A><V><V><T><A><D><V><A><W><P><G><F><A><P><R><Q><L><S><S><V><V><A><S><Q><I><D><L><H><A><A><Y><G><G><V><V><P><E><V><A><S><R><Q><H><V><E><T><L><P><F><V><L><E><A><A><L><Q><Q><A><G><L><E><V><A><E><V><D><A><I><A><V><T><C><A><P><G><L><V><G><S><L><L><V><G><L><M><G><A><K><T><L><A...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
Q2JI25
Q1QD10
SURE_PSYCK
Nucleoside 5'-monophosphate phosphohydrolase
Psychrobacter
<M><K><I><L><M><S><N><D><D><G><V><Y><A><P><G><L><L><A><L><Y><E><A><L><S><T><M><A><E><V><M><V><V><A><P><N><S><E><Q><S><G><C><A><S><A><L><S><I><T><T><P><L><Y><T><H><Q><L><P><S><G><F><I><A><V><N><G><T><P><A><D><C><I><Y><L><A><L><N><E><I><Y><S><D><T><D><F><D><C><V><I><T><G><I><N><S><G><A><N><L><G><Q><D><V><L><F><S><G><T><F...
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.<BOP>
Q1QD10
A8AKP9
FRSA_CITK8
Esterase FrsA
Citrobacter
<M><S><Q><A><N><L><S><E><T><L><F><K><P><R><F><K><H><P><E><T><S><T><L><V><R><R><F><N><H><G><T><Q><P><S><V><Q><S><T><L><D><G><K><N><V><P><H><W><Y><R><M><I><N><R><L><M><W><I><W><R><G><I><D><P><R><E><I><L><D><V><Q><A><R><I><V><M><S><E><A><E><R><T><D><K><E><L><Y><D><T><V><I><G><Y><R><G><G><N><W><I><F><E><W><S><K><Q><A><M><E...
Catalyzes the hydrolysis of esters.<BOP>
A8AKP9
B3DPR8
DNLJ_BIFLD
Polydeoxyribonucleotide synthase [NAD(+)]
Bifidobacterium
<M><S><T><N><E><Q><L><A><W><D><F><D><D><G><D><V><A><A><V><R><P><D><T><G><I><A><R><F><A><P><G><S><E><Q><W><I><A><A><L><Q><P><T><D><D><D><A><I><R><L><D><R><F><D><V><N><M><M><T><A><E><A><A><A><R><L><W><A><R><V><A><A><W><V><E><S><D><Q><I><A><Y><Y><I><D><D><S><P><V><S><S><D><A><A><Y><D><A><R><M><R><C><L><E><R><L><E><A><A><F...
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP>
B3DPR8
A5UWI3
COAD_ROSS1
Pantetheine-phosphate adenylyltransferase
Roseiflexus
<M><T><I><A><V><Y><P><G><S><F><D><P><V><T><N><G><H><L><D><I><A><A><R><A><S><R><I><F><D><T><V><I><M><A><V><F><D><R><P><N><K><Q><L><L><F><S><T><E><E><R><V><A><L><L><R><E><S><T><R><H><L><P><R><V><K><V><D><T><Y><S><T><L><T><V><D><Y><V><R><S><V><G><A><S><V><I><V><R><G><M><R><A><V><G><D><F><E><A><E><F><Q><L><A><Q><I><N><Q><T...
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP>
A5UWI3
Q0SNH1
GATB_BORAP
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Borreliella
<M><E><Y><K><L><V><I><G><L><E><I><H><I><Q><L><G><L><K><T><K><A><F><C><G><C><K><N><E><F><G><G><V><P><N><S><R><I><C><P><I><C><L><G><L><P><G><S><L><P><S><V><N><V><E><L><I><N><S><A><I><L><A><G><H><A><T><N><S><K><I><R><R><V><V><K><F><D><R><K><H><Y><Y><Y><P><D><L><P><K><G><Y><Q><I><S><Q><N><D><K><P><I><C><E><G><G><S><L><L><I...
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ...
Q0SNH1
B4F2G9
RPPH_PROMH
(Di)nucleoside polyphosphate hydrolase
Proteus
<M><I><D><D><D><G><Y><R><P><N><V><G><I><V><I><C><N><R><Q><G><Q><V><L><W><A><R><R><Y><G><Q><H><S><W><Q><F><P><Q><G><G><I><N><P><G><E><S><P><E><Q><A><M><Y><R><E><L><F><E><E><V><G><L><S><R><K><D><V><K><I><L><A><S><T><R><N><W><L><R><Y><K><L><P><K><R><L><V><R><W><D><T><K><P><V><C><I><G><Q><K><Q><R><W><F><L><L><Q><L><T><S><N...
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.<BOP>
B4F2G9
Q4FR09
MNMC_PSYA2
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Psychrobacter
<M><S><K><P><I><S><M><D><T><T><K><S><M><T><P><V><H><V><I><S><P><A><N><I><E><W><Q><T><D><D><A><G><N><K><V><P><V><S><G><E><F><G><D><V><Y><F><S><Q><A><D><D><L><A><E><S><R><H><V><F><L><V><H><N><Q><L><P><T><R><L><A><N><L><I><P><K><Q><C><F><T><I><C><E><L><G><F><G><T><G><L><N><L><L><A><T><W><Q><L><W><R><Q><L><R><L><T><H><P><H...
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s...
Q4FR09
Q9B506
CYB_TETBI
Ubiquinol-cytochrome-c reductase complex cytochrome b subunit
Tetrodontophora
<M><M><T><I><R><N><S><H><P><L><I><K><I><V><N><N><S><L><V><D><L><P><A><P><I><N><I><S><T><W><W><N><F><G><S><L><L><G><L><C><L><I><T><Q><I><M><T><G><L><F><L><A><M><H><Y><T><S><D><I><A><S><A><F><N><S><I><V><H><I><M><R><D><V><N><N><G><W><L><I><R><I><I><H><A><N><G><A><S><L><F><F><I><C><L><Y><L><H><T><G><R><N><I><Y><Y><N><S><F...
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is...
Q9B506
Q752S4
CWC24_ASHGO
Pre-mRNA-splicing factor CWC24
Eremothecium
<M><F><R><K><R><N><V><K><G><S><Q><Q><K><K><A><A><L><R><V><V><E><D><D><V><E><C><L><A><T><P><P><V><V><P><A><K><K><R><K><I><R><E><L><D><D><T><S><R><S><A><V><R><A><S><G><F><G><R><D><H><V><S><A><G><T><Q><E><A><V><A><R><A><T><D><D><A><P><D><R><R><A><E><S><S><G><A><R><T><A><V><G><S><N><V><R><T><R><V><V><M><D><Y><Q><P><D><V><C...
Involved in pre-mRNA splicing.<BOP>
Q752S4
C5DN02
ARO1_LACTC
Shikimate dehydrogenase
Lachancea
<M><K><V><E><L><S><K><V><P><I><L><G><K><D><V><V><H><V><G><F><D><I><A><D><H><I><V><D><T><I><F><Q><S><C><P><S><S><T><Y><V><V><I><N><D><T><N><V><E><K><I><P><H><Y><V><D><L><C><G><E><L><Q><A><K><L><K><S><G><S><R><I><L><Q><Y><S><V><K><P><G><E><A><H><K><T><R><E><Q><K><A><A><I><E><D><Y><L><L><S><E><G><C><T><R><D><T><V><I><I><A...
The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis.<BOP>
C5DN02
Q4R6T7
IQUB_MACFA
IQ and ubiquitin-like domain-containing protein
Macaca
<M><S><N><Q><P><K><K><Y><E><T><Q><N><I><A><N><S><T><E><E><S><D><A><F><D><I><V><T><I><P><V><P><S><E><E><P><Q><E><S><D><Q><T><E><E><H><E><S><G><I><E><Q><F><S><E><S><H><A><I><H><V><E><E><Q><S><D><R><S><F><S><S><L><E><P><D><S><E><Q><L><M><K><E><V><I><S><P><R><Q><V><S><Y><T><P><Q><H><H><E><K><Q><Y><A><M><Q><S><P><N><D><D><S...
May play roles in cilia formation and/or maintenance.<BOP>
Q4R6T7
P38678
GS1_NEUCR
Colonial temperature-sensitive protein 2
Neurospora
<M><A><G><L><F><K><D><I><W><H><A><M><T><S><Y><D><R><H><A><G><I><D><S><P><Y><R><T><G><R><H><V><P><L><N><R><N><S><G><L><A><G><V><T><T><A><S><D><S><R><A><D><I><N><S><P><Y><L><Q><G><D><G><R><G><S><T><M><S><F><D><T><A><Y><G><G><R><A><I><S><P><M><P><S><P><A><N><G><G><P><Y><S><P><G><L><V><S><Q><R><Q><S><V><H><Q><D><A><F><D><V...
Involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation.<BOP>
P38678
P10355
PT122_YEAST
Protein PET122, mitochondrial
Saccharomyces
<M><L><T><I><T><K><R><L><V><T><T><D><V><R><S><R><I><L><L><S><S><L><N><G><K><M><S><D><A><L><A><L><L><R><Q><Q><Q><Q><T><S><V><D><V><E><L><L><H><T><M><L><A><R><A><A><A><L><A><H><A><D><T><I><A><Y><M><W><Y><Q><H><V><M><P><R><R><L><P><V><E><G><R><L><L><C><E><M><A><G><V><A><L><Y><Q><D><R><L><F><L><P><A><Q><F><L><Q><H><Y><Q><A...
Required for expression of the mitochondrial gene for cytochrome c oxidase subunit 3 (COX3). PET122 seems to work by directly interacting with the small ribosomal subunit to promote translation initiation on the COX3 mRNA.<BOP>
P10355
Q72DU5
RNH2_DESVH
Ribonuclease HII
Desulfovibrio
<M><P><P><R><P><Q><R><L><A><P><V><A><D><L><P><P><V><F><A><G><I><D><E><A><G><R><G><C><L><A><G><P><V><V><A><A><A><V><I><L><P><Q><E><Y><A><L><P><G><L><T><D><S><K><K><L><T><A><A><R><R><E><S><L><A><E><G><I><R><S><C><A><V><T><W><G><I><G><V><V><W><P><R><D><I><D><R><I><N><I><L><Q><A><T><F><R><A><M><A><R><A><V><R><V><L><R><Q><P...
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP>
Q72DU5
P29901
MOXR_PARDE
Protein MoxR
Paracoccus
<M><D><S><N><I><S><D><W><H><A><R><F><R><D><A><E><A><A><L><N><G><V><V><L><G><Q><A><R><T><I><R><L><L><L><I><S><A><L><C><R><G><H><V><L><L><A><G><D><V><G><T><G><K><T><T><L><L><R><A><M><A><R><A><L><G><G><P><Y><G><R><V><E><G><T><V><D><L><L><P><T><D><L><I><Y><S><T><H><I><A><E><D><G><R><P><R><I><E><P><G><P><V><L><E><Q><G><E><D...
May be involved in the regulation of formation of active methanol dehydrogenase.<BOP>
P29901
P24779
3SA5_NAJKA
Cytotoxin II
Naja
<L><K><C><N><K><L><I><P><L><A><Y><K><T><C><P><A><G><K><N><L><C><Y><K><M><F><M><V><A><A><P><K><V><P><V><K><R><G><C><I><D><A><C><P><K><N><S><L><L><V><K><Y><V><C><C><N><T><D><R><C><N>
Shows cytolytic activity on many different cells by forming pore in lipid membranes. In vivo, increases heart rate or kills the animal by cardiac arrest. In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin a...
P24779
Q46149
TCDA_CLONO
N-acetylglucosaminyltransferase TcdA
Clostridium
<M><L><I><T><R><E><Q><L><M><K><I><A><S><I><P><L><K><R><K><E><P><E><Y><N><L><I><L><D><A><L><E><N><F><N><R><D><I><E><G><T><S><V><K><E><I><Y><S><K><L><S><K><L><N><E><L><V><D><N><Y><Q><T><K><Y><P><S><S><G><R><N><L><A><L><E><N><F><R><D><S><L><Y><S><E><L><R><E><L><I><K><N><S><R><T><S><T><I><A><S><K><N><L><S><F><I><W><I><G><G...
Active form of the toxin, which is released into the host cytosol following autoprocessing and inactivates small GTPases . Acts by mediating monoglycosylation of small GTPases of the Rho family (Rac1, RhoA, RhoG and Cdc42) in host cells at the conserved threonine residue located in the switch I region ('Thr-37/35'), us...
Q46149
P33300
SUR1_YEAST
Mannosyl phosphorylinositol ceramide synthase SUR1
Saccharomyces
<M><R><K><E><L><K><Y><L><I><C><F><N><I><L><L><L><L><S><I><I><Y><Y><T><F><D><L><L><T><L><C><I><D><D><T><V><K><D><A><I><L><E><E><D><L><N><P><D><A><P><P><K><P><Q><L><I><P><K><I><I><H><Q><T><Y><K><T><E><D><I><P><E><H><W><K><E><G><R><Q><K><C><L><D><L><H><P><D><Y><K><Y><I><L><W><T><D><E><M><A><Y><E><F><I><K><E><E><Y><P><W><F...
Involved in the synthesis of mannosyl phosphorylinositol ceramide . Catalyzes the addition of mannosyl to phosphorylinositol ceramide. Suppressor of RVS161 mutation .<BOP>
P33300
Q7VM59
MNMC_HAEDU
FAD-dependent cmnm(5)s(2)U34 oxidoreductase
Haemophilus
<M><H><K><L><T><F><A><Q><L><S><F><N><S><D><N><T><P><V><S><E><Q><F><D><D><I><Y><F><S><T><E><D><G><V><Q><E><S><Y><Y><V><F><Q><D><G><N><Q><L><W><Q><K><W><Q><N><H><H><R><S><A><F><V><I><A><E><T><G><F><G><T><G><L><N><F><L><A><V><A><E><K><F><Q><Q><F><R><S><T><F><P><D><S><P><L><K><R><L><Y><F><I><S><F><E><K><Y><P><L><T><Q><Q><Q...
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s...
Q7VM59
B1HN64
FLIT_LYSSC
Flagellar protein FliT
Lysinibacillus
<M><Y><Q><T><D><Q><L><L><Q><V><S><A><N><L><F><K><H><L><G><D><I><P><N><G><E><E><R><D><E><Y><I><E><T><I><N><T><M><L><D><K><R><E><T><I><I><K><G><L><K><Q><E><G><F><Q><F><D><E><Q><N><R><I><H><R><T><L><L><E><L><D><K><G><I><K><Q><R><L><A><A><V><M><D><A><V><K><Q><D><M><A><N><L><Q><K><T><K><K><S><E><Q><Q><Y><F><N><P><Y><S><N><V...
May act as an export chaperone for the filament capping protein FliD.<BOP>
B1HN64
P61556
SYCY2_MACFA
Transmembrane protein
Macaca
<M><G><L><L><L><L><V><L><I><L><T><P><L><L><A><A><Y><R><H><P><D><F><P><L><L><E><K><A><Q><Q><L><L><Q><S><T><G><S><P><Y><S><T><N><C><W><L><C><T><S><S><S><T><E><T><P><G><T><A><Y><P><A><S><P><R><E><W><T><S><I><E><A><E><L><H><I><S><Y><Q><W><D><P><N><L><K><G><L><M><T><P><A><N><S><L><L><S><T><V><K><Q><D><F><P><D><I><R><Q><K><P...
Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein...
P61556
P80172
HBLA_BACCE
Enterotoxin 40 kDa subunit
Bacillus cereus group
<M><I><K><K><I><P><Y><K><L><L><A><V><S><T><L><L><T><I><T><T><A><N><V><V><S><P><V><A><T><F><A><S><E><I><E><Q><T><N><N><G><D><T><A><L><S><A><N><E><A><K><M><K><E><T><L><Q><K><A><G><L><F><A><K><S><M><N><A><Y><S><Y><M><L><I><K><N><P><D><V><N><F><E><G><I><T><I><N><G><Y><V><D><L><P><G><R><I><V><Q><D><Q><K><N><A><R><A><H><A><V...
Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus.<BOP>
P80172
A8GVN8
COXX_RICB8
Heme O synthase
belli group
<M><N><S><L><T><K><S><I><N><L><D><K><V><S><Y><P><Q><S><T><V><K><D><Y><I><L><L><M><K><P><R><V><M><S><L><V><V><F><T><G><F><S><G><M><W><L><A><P><N><S><L><H><P><F><I><S><V><I><A><L><I><C><I><A><I><G><A><G><S><A><G><A><I><N><M><W><Y><D><R><D><I><D><A><L><M><K><R><T><Q><K><R><P><I><V><R><G><A><I><E><A><D><E><A><L><S><F><G><L...
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.<BOP>
A8GVN8
O08677
KNG1_MOUSE
Kininogen-1 light chain
Mus
<M><K><L><I><T><T><L><L><L><C><S><G><L><L><L><T><L><T><Q><G><E><E><A><Q><E><I><D><C><N><D><E><A><V><F><Q><A><V><D><F><S><L><K><Q><F><N><P><G><V><K><S><G><N><Q><Y><M><L><H><R><V><I><E><G><T><K><T><D><G><S><P><T><F><Y><S><F><K><Y><L><I><K><E><G><N><C><S><A><Q><S><G><L><A><W><Q><D><C><D><F><K><D><A><E><E><A><A><T><G><E><C...
The active peptide bradykinin is a potent vasodilatator that is released from HMW-kininogen shows a variety of physiological effects: (A) influence in smooth muscle contraction, (B) induction of hypotension, (C) natriuresis and diuresis, (D) decrease in blood glucose level, (E) it is a mediator of inflammation and caus...
O08677
Q6P3D7
SPIC_MOUSE
Pu.1-related factor
Mus
<M><T><C><C><I><D><Q><D><S><L><G><Q><T><F><Q><D><A><I><D><I><L><I><Q><Q><S><A><G><E><S><Q><Y><S><S><E><N><R><N><Y><M><A><I><I><N><P><Y><P><H><V><R><G><N><A><N><Y><Y><G><M><S><P><T><E><N><P><L><Y><D><W><R><G><V><T><N><G><S><A><D><L><Y><L><E><G><G><F><H><Q><S><V><Q><N><I><A><E><S><Q><L><V><Q><P><P><F><F><Q><Q><K><G><G><R...
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.<BOP>
Q6P3D7
B1KDR7
KDSB_SHEWM
CMP-8-amino-3,8-dideoxy-manno-octulosonate synthase
Shewanella
<M><N><V><T><L><L><I><P><A><R><Y><G><S><S><R><F><P><G><K><P><L><A><P><I><N><G><K><P><M><I><Q><H><V><Y><E><R><A><S><L><A><K><G><L><T><A><I><Y><V><A><T><D><D><D><R><I><K><E><A><V><E><A><F><G><G><K><V><V><M><T><D><P><Q><A><A><S><G><T><D><R><I><E><D><A><I><T><Q><L><G><L><K><D><D><D><L><I><V><N><L><Q><G><D><Q><P><L><I><D><P...
Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.<BOP>
B1KDR7
A0R2V7
GLYA_MYCS2
Serine hydroxymethyltransferase
Mycolicibacterium
<M><A><A><D><P><S><S><N><S><S><S><V><P><A><A><N><G><A><D><Y><A><D><T><A><S><A><A><Y><Q><A><A><L><Q><V><I><E><S><V><E><P><R><V><A><A><A><T><R><K><E><L><A><D><Q><R><D><S><L><K><L><I><A><S><E><N><Y><A><S><P><A><V><L><L><T><M><G><T><W><F><S><D><K><Y><A><E><G><T><I><G><H><R><F><Y><A><G><C><Q><N><V><D><T><V><E><S><V><A><A><E...
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a...
A0R2V7
O74252
STE12_EMENI
Transcription factor steA
Aspergillus subgen. Nidulantes
<M><Y><S><Q><H><G><A><P><M><A><P><P><Q><K><P><E><T><F><M><L><S><N><E><A><Q><Q><S><L><P><H><D><A><Q><V><A><L><Q><Q><V><D><N><L><K><Y><F><L><L><S><A><P><V><D><W><Q><P><D><Q><L><I><R><R><F><L><L><P><T><G><D><Y><I><S><C><V><L><W><S><N><L><F><H><I><S><G><T><D><I><V><R><C><L><A><F><R><F><Q><A><F><G><R><P><V><K><N><S><K><K><F...
Transcription factor involved in sexual reproduction. Required for cleistothecial development and ascosporogenesis. Not required for asexual reproduction (conidiation). May act to repress medA expression.<BOP>
O74252
Q9RWN9
MURC_DEIRA
UDP-N-acetylmuramoyl-L-alanine synthetase
Deinococcus
<M><P><Q><L><P><M><T><D><S><A><P><L><P><T><P><A><P><S><S><P><A><Q><P><S><A><Q><P><S><L><H><Y><H><L><L><G><I><G><G><I><G><M><S><A><F><A><R><L><L><A><T><R><G><H><R><V><S><G><C><D><Q><N><L><G><A><Q><T><A><G><L><E><A><Q><G><I><P><V><A><A><G><H><A><A><A><H><V><T><E><E><P><F><G><K><I><D><V><L><V><A><S><E><A><V><P><K><S><H><P...
Cell wall formation.<BOP>
Q9RWN9
A9BUK7
MURC_DELAS
UDP-N-acetylmuramoyl-L-alanine synthetase
Delftia
<M><K><H><A><I><H><H><I><H><F><V><G><I><G><G><A><G><M><S><G><I><A><E><V><L><H><N><L><G><Y><A><I><S><G><S><D><L><S><D><S><A><T><L><R><R><L><A><G><L><G><I><A><T><H><V><G><H><A><A><A><H><I><E><G><A><D><A><V><V><T><S><T><A><V><Q><S><D><N><P><E><V><L><A><A><R><E><R><K><I><P><V><V><P><R><A><L><M><L><A><E><L><M><R><F><K><Q><G...
Cell wall formation.<BOP>
A9BUK7
D5MTF8
HGL1D_WHEAT
Beta-glucosidase 1d
Triticum
<M><A><L><L><A><A><A><T><L><N><P><T><T><H><L><S><L><R><S><R><A><G><R><N><S><E><N><L><W><L><R><S><A><A><S><S><Q><K><S><K><G><R><F><C><N><L><T><V><R><A><G><T><P><S><K><P><A><E><P><I><G><P><V><F><T><K><L><K><P><W><Q><I><P><K><R><D><W><F><D><K><D><F><L><F><G><A><S><T><S><A><Y><Q><I><E><G><A><W><N><E><D><G><K><G><P><S><T><W...
Acts in defense of young plant parts against pests via the production of hydroxamic acids from hydroxamic acid glucosides. Enzymatic activity is highly correlated with plant growth. The preferred substrate is DIMBOA-beta-D-glucoside.<BOP>
D5MTF8
A6M3L2
RS6_CLOB8
30S ribosomal protein S6
Clostridium
<M><R><K><Y><E><T><I><F><I><L><N><P><S><F><D><E><E><T><V><K><A><N><I><E><K><F><K><G><V><I><E><N><G><G><G><T><V><E><N><V><D><F><W><G><K><R><K><L><A><Y><E><I><S><K><V><S><E><G><F><Y><T><L><V><N><F><T><A><N><P><E><L><P><R><E><L><D><R><I><F><R><I><T><D><G><V><I><R><H><I><I><V><N><E><Q><V>
Binds together with S18 to 16S ribosomal RNA.<BOP>
A6M3L2
Q03615
SAEG2_CAEEL
Suppressor of activated egl-4 protein 2
Caenorhabditis
<M><R><I><V><I><L><D><E><L><L><S><R><E><M><D><G><S><N><D><G><S><S><A><R><V><N><S><L><K><H><V><I><K><R><N><K><M><D><M><A><D><D><A><P><S><S><L><D><L><M><R><R><I><F><Q><A><E><I><S><R><E><I><H><Q><I><M><E><R><H><T><R><T><T><L><L><P><A><I><E><N><L><R><K><N><G><H><V><V><D><E><S><V><L><N><G><L><Y><C><N><I><L><E><A><A><K><K><P...
As a likely component of a histone deacetylase complex, together with saeg-1 and hda-2, functions downstream of the cAMP-dependent kinase egl-4 to regulate the expression of genes required for egg-laying and foraging .<BOP>
Q03615
A7FXG3
MNMA2_CLOB1
tRNA-specific 2-thiouridylase MnmA 2
Clostridium
<M><S><K><G><I><V><A><L><A><M><S><G><G><V><D><S><S><V><S><A><Y><I><L><K><E><R><G><Y><D><V><I><G><I><Y><M><D><L><W><R><D><E><R><K><G><Y><C><N><K><S><A><A><E><D><A><R><R><V><A><E><K><L><D><I><P><F><H><V><I><N><I><E><K><K><F><K><D><N><V><I><D><Y><F><I><D><E><Y><L><S><G><R><T><P><N><P><C><V><A><C><N><K><T><I><K><F><E><A><F...
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.<BOP>
A7FXG3
Q95239
CASK_RANTA
Kappa-casein
Rangifer
<V><A><L><I><N><N><Q><F><L><P><Y><P><Y><Y><A><K><P><G><A><V><R><S><P><A><Q><I><L><Q><W><Q><V><L><P><N><T><V><P><A><K><S><C><Q><A><Q><P><T><T><L><A><R><H><P><H><P><R><L><S><F><M><A><I><P><P><K><K><N><Q><D><K><T><D><I><P><T><I><N><T><I><A><T><V><E><S><T><I><T><P><T><T><E><A><I><V><D><T><V><A><T><L><E><A><S><S><E><V><I><E...
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.<BOP>
Q95239
C0Q3A6
WECF_SALPC
TDP-Fuc4NAc:lipid II Fuc4NAc transferase
Salmonella
<M><T><V><L><I><H><V><L><G><S><D><I><P><H><H><N><H><T><V><L><R><F><F><N><D><T><L><A><A><T><S><E><H><A><R><E><F><M><V><A><G><E><D><N><G><F><T><E><S><C><P><A><L><S><L><H><F><Y><G><S><K><K><V><L><A><Q><A><V><I><A><K><A><K><A><N><R><R><Q><R><F><F><F><H><G><Q><F><N><T><S><L><W><L><A><L><L><S><G><G><I><K><P><A><Q><F><Y><W><H...
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.<BOP>
C0Q3A6
Q6MAD8
FLOA_PARUW
Flotillin-like protein FloA
Candidatus Protochlamydia
<M><S><T><L><L><L><Q><N><L><L><E><N><G><T><E><F><Y><F><F><I><F><V><L><A><I><V><L><L><I><I><L><S><V><I><G><K><F><I><S><L><W><F><Q><A><F><V><S><G><T><P><I><P><L><F><N><I><I><G><M><S><L><R><K><I><P><P><R><E><I><V><N><A><R><I><N><L><Y><K><A><G><L><K><D><I><H><V><G><D><L><E><T><H><Y><L><A><G><G><H><V><P><N><V><V><E><A><L><I...
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts. FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.<BOP>
Q6MAD8
B0X9V1
FBSP1_CULQU
F-box/SPRY domain-containing protein 1
Culex
<M><D><D><D><L><T><E><Y><A><P><D><I><P><D><N><V><L><E><L><I><F><S><Y><L><K><L><Q><D><L><R><N><C><A><L><V><C><K><S><W><H><R><F><L><S><D><E><N><N><E><V><W><R><A><Q><C><M><Q><K><L><S><P><D><A><F><K><T><D><L><L><S><V><V><P><T><Y><K><A><K><L><R><A><F><F><H><A><W><N><P><Y><D><C><S><R><H><V><Y><I><K><P><N><G><F><T><L><H><R><N...
Required in the presynaptic motoneuron to down-regulate the levels of wnd and restrain synaptic terminal growth at the neuromuscular junction (NMJ).<BOP>
B0X9V1
Q7VDN6
MTAP_PROMA
5'-methylthioadenosine phosphorylase
Prochlorococcus
<M><I><N><K><H><F><S><S><E><E><I><E><Q><D><G><K><S><C><L><L><K><N><A><R><L><G><V><L><G><G><S><G><L><Y><S><I><D><S><I><E><N><I><K><E><L><D><I><E><T><P><Y><G><K><P><S><D><S><L><R><I><G><N><L><G><G><M><E><V><V><F><L><A><R><H><G><R><H><H><I><Y><T><P><T><E><I><P><Y><R><A><N><I><W><A><L><R><S><L><N><V><R><W><I><L><S><P><S><A...
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethioni...
Q7VDN6
A6W3T9
MNMG_MARMS
Glucose-inhibited division protein A
Marinomonas
<M><D><F><P><S><R><F><D><V><I><V><V><G><G><G><H><A><G><T><E><A><A><L><A><A><A><R><M><G><V><K><T><L><L><L><S><H><N><I><E><T><L><G><Q><M><S><C><N><P><A><I><G><G><I><G><K><S><H><L><V><K><E><I><D><A><L><D><G><A><M><A><L><A><T><D><Q><A><G><I><Q><F><R><T><L><N><S><R><K><G><P><A><V><R><A><T><R><A><Q><A><D><R><I><L><Y><K><A><A...
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP>
A6W3T9
Q6FEZ7
AROE_ACIAD
Shikimate dehydrogenase (NADP(+))
Acinetobacter
<M><T><K><Q><F><A><V><I><G><N><P><I><E><Q><S><R><S><P><E><L><H><H><A><F><A><E><K><L><G><I><E><L><N><Y><S><K><R><L><A><P><L><D><G><F><E><A><N><V><K><T><F><F><D><Q><G><G><L><G><I><N><V><T><V><P><F><K><E><Q><A><F><A><M><C><H><Q><L><T><E><R><A><K><I><A><K><A><V><N><T><L><W><I><E><N><G><Q><L><H><G><D><N><T><D><G><Q><G><L><V...
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).<BOP>
Q6FEZ7
A9W383
RLMN_METEP
tRNA m2A37 methyltransferase
Methylorubrum
<M><A><T><A><S><F><D><S><A><P><G><A><S><R><A><L><P><A><I><E><K><A><P><E><V><T><A><L><S><T><L><P><G><R><K><A><S><L><V><G><L><T><R><E><G><L><K><Q><A><L><I><G><I><G><V><P><E><R><E><T><R><M><R><V><S><Q><V><W><H><W><I><Y><V><R><G><A><R><E><F><S><E><M><T><N><V><G><K><G><L><K><A><Q><L><A><D><H><F><T><L><E><R><P><E><V><V><T><E...
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.<BOP>
A9W383
Q8CWM5
MIAA_THEVB
Isopentenyl-diphosphate:tRNA isopentenyltransferase
Thermosynechococcus
<M><G><D><A><G><L><I><V><I><G><G><A><T><A><T><G><K><T><A><L><A><I><A><L><A><Q><Q><L><N><S><V><I><L><S><A><D><S><R><Q><V><Y><R><G><F><D><I><G><T><A><K><P><T><P><A><Q><Q><Q><Q><V><R><H><H><L><I><D><I><C><D><P><R><E><T><L><T><L><A><I><Y><Q><A><K><A><Q><A><L><I><A><H><Y><H><A><Q><G><I><T><P><L><L><V><G><G><T><G><L><Y><I><R...
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).<BOP>
Q8CWM5
Q6FUD0
PYRG_CANGA
UTP--ammonia ligase
Nakaseomyces/Candida clade
<M><K><Y><V><V><V><S><G><G><V><I><S><G><I><G><K><G><V><L><A><S><S><T><G><M><L><L><K><T><L><G><L><K><V><T><S><I><K><I><D><P><Y><M><N><I><D><A><G><T><M><S><P><L><E><H><G><E><C><F><V><L><N><D><G><G><E><T><D><L><D><L><G><N><Y><E><R><Y><L><N><V><T><L><T><K><D><H><N><I><T><T><G><K><I><Y><S><H><V><I><A><K><E><R><K><G><D><Y><L...
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.<BOP>
Q6FUD0
Q1ACI1
PSAJ_CHAVU
PSI-J
Chara
<M><Q><D><V><K><T><Y><L><S><T><A><P><V><L><A><T><L><W><F><G><L><L><A><G><I><L><I><E><I><N><R><F><F><P><D><A><L><V><L><P><Y>
May help in the organization of the PsaE and PsaF subunits.<BOP>
Q1ACI1
B6HZ33
PDXA_ECOSE
4-(phosphohydroxy)-L-threonine dehydrogenase
Escherichia
<M><V><K><T><Q><R><V><V><I><T><P><G><E><P><A><G><I><G><P><D><L><V><V><Q><L><A><Q><R><E><W><P><V><E><L><V><V><C><A><D><T><T><L><L><T><D><R><A><A><M><L><G><L><P><L><T><L><R><P><Y><S><P><N><S><P><A><Q><P><Q><T><T><G><T><L><T><L><L><P><V><A><L><R><E><S><V><T><A><G><Q><L><A><I><E><N><G><H><Y><V><V><E><T><L><A><R><A><C><D><G...
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).<BOP>
B6HZ33
P70083
AT2A1_MAKNI
Endoplasmic reticulum class 1/2 Ca(2+) ATPase
Makaira
<M><E><N><A><H><T><K><S><P><A><E><C><L><S><Y><F><G><V><N><E><H><T><G><L><S><P><D><Q><F><K><K><N><L><D><K><F><G><Y><N><E><L><P><A><E><E><G><K><S><I><W><D><L><I><V><E><Q><F><E><D><L><L><V><R><I><L><L><L><A><A><C><I><S><F><V><L><A><W><F><E><E><G><E><E><T><I><T><A><F><V><E><P><F><V><I><L><L><I><L><I><A><N><A><I><V><G><V><W...
Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium seque...
P70083
Q02638
CEBP_DROVI
Slow border cell protein
Drosophila
<M><L><N><M><E><S><P><Q><M><Y><A><D><A><V><Q><T><L><A><H><V><D><L><K><K><Q><P><Q><P><L><P><Q><Q><A><T><I><G><Q><I><T><L><T><A><M><S><S><A><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><Q><V><T><T><D><A><N><N><N><A><T><V><Q><D><A><A><L><L><V><K><Q><H><A><M><Q><Q><M><Q><L><S><N><N><N><S><N><N><L><L><Q...
May be required for the expression of gene products mediating border cell migration. Among the DNA sequences that this protein binds with high affinity is a conserved site within the promoter of its gene.<BOP>
Q02638
Q8W9N3
COX2_DUGDU
Cytochrome c oxidase polypeptide II
Dugong
<M><P><Y><P><L><Q><L><G><L><Q><D><A><T><S><P><I><M><E><E><L><T><H><F><H><D><H><T><L><M><I><V><F><L><I><S><S><L><V><L><Y><I><I><S><S><M><L><T><T><K><L><T><H><T><S><T><M><D><A><Q><E><V><E><T><I><W><T><I><L><P><A><M><I><L><I><L><I><A><L><P><S><L><R><I><L><Y><M><M><D><E><I><N><D><P><S><L><T><V><K><T><M><G><H><Q><W><Y><W><S...
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CII...
Q8W9N3
Q7SGY6
DHSD_NEUCR
Succinate-ubiquinone reductase membrane anchor subunit
Neurospora
<M><A><S><V><A><R><S><S><A><L><L><K><Q><V><A><A><Q><Q><S><V><A><A><N><G><L><R><V><A><A><F><H><T><T><S><R><K><S><L><L><P><P><P><P><Q><R><I><E><G><T><V><N><D><P><V><E><V><P><P><P><S><P><S><H><G><S><Y><H><W><T><F><D><R><V><V><A><A><G><L><I><P><L><T><V><A><P><F><A><A><G><S><L><N><P><T><M><D><A><V><L><A><A><T><I><L><I><H><S...
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).<BOP>
Q7SGY6
A3PAW2
GLMM_PROM0
Phosphoglucosamine mutase
Prochlorococcus
<M><Q><S><I><F><G><T><D><G><I><R><G><R><F><N><E><E><I><T><Y><S><L><A><Y><K><V><G><Y><A><L><G><S><T><L><E><N><K><N><P><I><L><I><G><R><D><T><R><I><S><G><N><I><L><L><Q><A><I><T><Q><G><I><N><E><S><G><K><K><F><I><N><L><G><I><C><P><T><P><A><I><P><Y><L><I><K><E><E><N><L><S><S><G><I><M><I><S><A><S><H><N><P><P><E><Y><N><G><I><K...
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.<BOP>
A3PAW2
P10297
RIP1_PHYAM
rRNA N-glycosidase
Phytolacca
<M><K><S><M><L><V><V><T><I><S><I><W><L><I><L><A><P><T><S><T><W><A><V><N><T><I><I><Y><N><V><G><S><T><T><I><S><K><Y><A><T><F><L><N><D><L><R><N><E><A><K><D><P><S><L><K><C><Y><G><I><P><M><L><P><N><T><N><T><N><P><K><Y><V><L><V><E><L><Q><G><S><N><K><K><T><I><T><L><M><L><R><R><N><N><L><Y><V><M><G><Y><S><D><P><F><E><T><N><K><C...
Possesses antiviral potency. Inhibits viral infection of plants (tobacco mosaic virus) . Inhibits protein synthesis . Releases both adenine and guanine from Escherichia coli rRNA in vitro. Activity on guanine is 20 times slower than that on adenine .<BOP>
P10297
C0NQL8
DRE2_AJECG
Anamorsin homolog
Histoplasma
<M><A><T><T><G><R><V><L><L><L><S><P><P><S><L><S><S><H><P><E><K><L><N><T><V><L><K><S><H><T><R><D><K><T><D><L><Q><M><L><D><R><L><A><H><G><L><V><S><L><P><E><S><T><Y><D><I><V><L><L><L><T><G><A><D><N><T><L><A><E><T><H><S><L><L><N><R><E><L><I><Q><R><V><V><H><S><L><R><P><A><G><K><L><R><N><R><E><N><K><P><W><G><L><S><D><G><N><G...
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CF...
C0NQL8
Q9H4T2
ZSC16_HUMAN
Zinc finger protein 435
Homo
<M><T><T><A><L><E><P><E><D><Q><K><G><L><L><I><I><K><A><E><D><H><Y><W><G><Q><D><S><S><S><Q><K><C><S><P><H><R><R><E><L><Y><R><Q><H><F><R><K><L><C><Y><Q><D><A><P><G><P><R><E><A><L><T><Q><L><W><E><L><C><R><Q><W><L><R><P><E><C><H><T><K><E><Q><I><L><D><L><L><V><L><E><Q><F><L><S><I><L><P><K><D><L><Q><A><W><V><R><A><H><H><P><E...
May be involved in transcriptional regulation.<BOP>
Q9H4T2
P18075
BMP7_HUMAN
Osteogenic protein 1
Homo
<M><H><V><R><S><L><R><A><A><A><P><H><S><F><V><A><L><W><A><P><L><F><L><L><R><S><A><L><A><D><F><S><L><D><N><E><V><H><S><S><F><I><H><R><R><L><R><S><Q><E><R><R><E><M><Q><R><E><I><L><S><I><L><G><L><P><H><R><P><R><P><H><L><Q><G><K><H><N><S><A><P><M><F><M><L><D><L><Y><N><A><M><A><V><E><E><G><G><G><P><G><G><Q><G><F><S><Y><P><Y...
Growth factor of the TGF-beta superfamily that plays important role in various biological processes, including embryogenesis, hematopoiesis, neurogenesis and skeletal morphogenesis . Initiates the canonical BMP signaling cascade by associating with type I receptor ACVR1 and type II receptor ACVR2A . Once all three comp...
P18075
Q4KME6
GGYF2_DANRE
Trinucleotide repeat-containing gene 15 protein
Danio
<M><A><E><T><Q><T><L><N><F><G><P><E><W><L><R><A><L><A><G><G><V><G><S><S><I><V><A><S><P><P><L><S><P><A><L><P><K><Y><K><L><A><D><Y><R><Y><G><R><E><E><M><L><A><L><Y><V><K><D><N><M><I><P><V><D><L><H><D><K><E><F><L><P><I><L><Q><E><E><P><L><P><P><L><A><L><V><P><F><T><E><E><E><Q><R><N><F><S><M><S><V><N><S><A><A><V><L><R><L><T...
Key component of the 4EHP-GYF2 complex, a multiprotein complex that acts as a repressor of translation initiation.<BOP>
Q4KME6
A5WCU4
LPXC_PSYWF
UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase
Psychrobacter
<M><K><Q><R><T><L><K><Q><P><I><T><V><V><G><I><G><L><H><S><G><Q><D><V><T><L><T><L><Q><P><S><E><V><N><T><G><I><R><F><L><R><T><D><I><E><D><A><P><L><I><A><A><D><A><F><L><V><T><D><T><V><M><S><S><N><L><M><V><N><G><I><K><I><G><T><V><E><H><L><L><S><A><L><A><G><F><G><I><D><N><L><L><I><K><V><S><D><A><E><I><P><I><M><D><G><S><A><A...
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.<BOP>
A5WCU4
Q5ZLA9
TM263_CHICK
Transmembrane protein 263
Gallus
<M><N><Q><T><D><K><S><H><Q><E><V><P><S><Y><L><H><D><E><P><P><E><G><S><I><K><D><H><P><Q><Q><Q><P><S><M><L><S><R><V><T><G><G><I><F><S><V><T><K><G><A><V><G><A><T><I><G><G><V><A><W><I><G><G><K><S><L><E><I><T><K><T><A><V><T><S><V><P><S><M><G><V><G><L><V><K><G><S><V><S><A><V><A><G><G><V><T><A><V><G><S><A><V><A><S><K><V><P><L...
May be involved in the growth pathway.<BOP>
Q5ZLA9
A5EXD7
FABH_DICNV
3-oxoacyl-[acyl-carrier-protein] synthase III
Dichelobacter
<M><M><Y><S><K><I><I><G><T><G><G><Y><L><P><S><R><I><V><S><N><D><E><L><S><Q><S><M><Q><T><S><D><E><W><I><Y><S><R><T><G><I><R><Q><R><H><L><A><S><P><D><E><S><C><S><D><M><A><F><Y><A><A><K><R><A><L><E><N><A><H><I><E><A><D><A><I><D><L><I><I><V><A><T><S><T><P><E><H><I><F><P><S><T><A><T><V><V><Q><S><R><L><S><C><Q><R><A><A><A><F...
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-A...
A5EXD7
Q5L6Q2
LPXK_CHLAB
Lipid A 4'-kinase
Chlamydia
<M><K><T><R><F><P><S><P><F><F><I><F><Y><R><R><L><T><V><A><I><S><L><G><K><I><L><G><W><G><C><F><G><K><L><L><S><W><I><F><A><A><T><V><S><F><R><R><K><V><L><S><S><A><P><H><R><V><S><S><T><V><I><S><V><G><N><I><V><L><G><G><S><G><K><T><P><T><V><L><W><L><A><E><V><L><K><A><R><G><Y><S><C><A><I><L><S><R><G><Y><K><G><K><C><S><G><Q><R...
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).<BOP>
Q5L6Q2
Q0HXR3
TRUB_SHESR
tRNA-uridine isomerase
Shewanella
<M><A><R><R><S><K><G><R><F><I><D><G><I><V><L><L><D><K><A><T><G><M><S><S><N><F><A><L><Q><R><V><K><R><F><F><N><A><N><K><A><G><H><T><G><A><L><D><P><L><A><T><G><M><L><P><V><C><L><G><E><A><T><K><F><S><Q><H><L><L><D><S><D><K><R><Y><L><V><T><A><K><L><G><Q><R><T><D><T><S><D><S><D><G><E><V><V><Q><T><R><P><L><E><F><T><E><A><Q><L...
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP>
Q0HXR3
Q0TFK1
GLPB_ECOL5
Anaerobic glycerol-3-phosphate dehydrogenase subunit B
Escherichia
<M><R><F><D><T><V><I><M><G><G><G><L><A><G><L><L><C><G><L><Q><L><Q><K><H><G><L><R><C><A><I><V><T><R><G><Q><S><A><L><H><F><S><S><G><S><L><D><L><L><S><H><L><P><D><G><Q><P><V><T><E><I><H><S><G><L><E><S><L><R><Q><Q><A><P><A><H><P><Y><T><L><L><G><P><Q><R><V><L><D><L><A><C><Q><A><Q><A><L><I><A><E><S><G><A><Q><L><Q><G><S><V><E...
Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor.<BOP>
Q0TFK1
A8M2A6
PAFA_SALAI
Pup-conjugating enzyme
Salinispora
<M><E><R><R><I><F><G><L><E><T><E><Y><G><V><T><C><T><Y><R><G><Q><R><R><L><S><P><D><E><V><A><R><Y><L><F><R><R><V><V><S><W><G><R><S><S><N><V><F><L><R><N><G><A><R><L><Y><L><D><V><G><S><H><P><E><Y><A><T><P><E><C><D><S><V><A><D><L><V><A><H><D><R><A><G><E><R><I><L><E><G><L><L><V><D><A><E><K><R><L><H><D><E><G><I><A><G><E><I><Y...
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and t...
A8M2A6
Q609V1
BIOF_METCA
8-amino-7-ketopelargonate synthase
Methylococcus
<M><T><F><D><P><A><S><A><L><A><E><I><K><A><R><D><A><Y><R><W><R><R><I><V><E><S><P><Q><D><T><R><V><V><I><D><G><A><P><R><V><N><F><C><S><N><D><Y><L><G><L><A><N><H><P><A><V><R><E><A><F><R><R><G><V><D><R><W><G><V><G><S><G><A><S><H><L><V><C><G><H><S><A><A><H><H><A><L><E><E><E><L><A><E><F><T><G><R><P><R><A><L><L><F><S><T><G><Y...
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.<BOP>
Q609V1
B6EKL2
PIMT_ALISL
Protein-beta-aspartate methyltransferase
Aliivibrio
<M><M><H><S><R><S><E><L><L><D><Q><F><L><R><Q><Q><G><I><L><N><E><D><I><L><L><A><I><R><Q><L><P><R><E><R><F><V><P><E><A><L><A><H><Q><A><Y><Q><N><N><A><L><P><I><G><E><G><Q><T><I><S><Q><P><Y><I><V><A><K><M><T><E><L><L><E><L><Q><Y><D><S><N><L><L><E><I><G><T><G><S><G><Y><Q><T><A><V><L><A><K><L><V><G><H><V><H><S><V><E><R><I><K...
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.<BOP>
B6EKL2
A4XLM2
OTC_CALS8
Ornithine carbamoyltransferase
Caldicellulosiruptor
<M><R><H><F><L><S><L><N><E><L><T><K><D><E><I><L><Y><L><V><D><L><A><C><R><L><K><S><E><V><K><R><G><F><F><F><P><Y><L><K><H><K><A><L><G><L><I><F><T><K><A><S><T><R><T><R><V><S><F><E><V><G><I><N><Q><L><G><G><Y><S><L><Y><L><S><K><N><D><L><Q><L><G><R><G><E><T><I><E><D><T><A><K><V><L><S><R><Y><L><D><L><I><V><I><R><T><Y><A><Q><S...
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.<BOP>
A4XLM2
A0A353
PETL_COFAR
Cytochrome b6-f complex subunit VI
Coffea
<M><L><T><I><T><S><Y><F><G><F><L><L><A><A><L><T><I><T><S><A><L><F><I><G><L><N><K><I><R><L><I>
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex...
A0A353