accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
P44201
LYSO_HAEIN
Putative lysine exporter
Haemophilus
<M><E><E><L><L><S><A><V><I><I><G><I><V><L><G><W><L><C><K><D><W><L><H><F><P><N><G><S><N><L><Y><V><L><I><T><L><I><F><F><V><G><I><Q><L><R><N><N><G><I><S><L><K><E><V><L><L><N><K><Q><G><L><M><M><G><A><I><F><T><L><S><S><L><I><G><G><V><I><S><A><F><F><L><S><M><P><I><T><Q><G><L><A><F><S><S><G><F><G><W><Y><S><L><S><S><V><V><L><T...
Mediates export of lysine.<BOP>
P44201
Q9KV08
HFLC_VIBCH
Protein HflC
Vibrio
<M><R><K><L><L><I><P><S><I><V><L><I><I><A><A><L><L><M><S><M><F><V><I><P><E><G><E><R><G><I><V><I><R><F><G><R><V><L><K><D><N><N><D><L><A><R><I><Y><E><P><G><L><H><F><K><M><P><L><F><D><R><V><K><T><L><D><A><R><I><Q><T><M><D><G><R><S><D><R><F><V><T><S><E><K><K><D><V><I><I><D><T><Y><V><K><W><R><I><E><D><F><G><Q><Y><Y><L><A><T...
HflC and HflK could regulate a protease.<BOP>
Q9KV08
B1WQW1
RNZ_CROS5
tRNase Z
Crocosphaera subtropica
<M><E><I><T><F><L><G><T><S><S><G><V><P><T><R><S><R><N><V><S><S><V><A><L><R><L><P><Q><R><A><E><V><W><L><F><D><C><G><E><G><T><Q><H><Q><L><L><R><S><D><V><K><I><S><Q><I><T><R><I><F><V><T><H><M><H><G><D><H><I><Y><G><L><T><G><L><L><A><S><C><G><L><A><G><S><G><Q><P><I><E><I><Y><G><P><P><E><L><K><D><Y><L><K><A><C><A><K><Y><S><H...
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.<BOP>
B1WQW1
Q54J98
GACX_DICDI
GTPase activating factor for raC protein X
Dictyostelium
<M><S><N><N><N><N><R><A><S><I><Y><G><G><L><G><S><V><G><K><I><F><G><A><P><L><L><D><V><V><M><N><Q><K><S><K><T><T><S><L><N><S><S><S><S><A><T><N><N><N><N><S><T><V><E><E><V><N><I><P><L><F><L><H><N><G><F><K><Y><I><I><Q><H><G><L><G><I><E><G><I><F><R><I><A><G><T><K><D><K><V><K><Q><L><Q><M><Q><L><D><K><G><E><N><I><D><Y><D><A><S...
Rho GTPase-activating protein involved in the signal transduction pathway.<BOP>
Q54J98
Q0IA94
PETN_SYNS3
Cytochrome b6-f complex subunit VIII
unclassified Synechococcus
<M><L><F><T><I><A><W><A><S><L><A><A><V><F><S><F><S><I><A><M><V><V><W><G><R><N><G><D><G><T><L><N><F>
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.<BOP>
Q0IA94
Q0QLF5
HMGD_EUBBA
2-(hydroxymethyl)glutarate dehydrogenase
Eubacterium
<M><E><K><S><I><K><I><G><F><I><G><L><G><A><M><G><K><P><M><A><I><N><L><L><K><E><G><V><T><V><Y><A><F><D><L><M><E><A><N><V><A><A><V><V><A><Q><G><A><Q><A><C><E><N><N><Q><K><V><A><A><A><S><D><I><I><F><T><S><L><P><N><A><G><I><V><E><T><V><M><N><G><P><G><G><V><L><S><A><C><K><A><G><T><V><I><V><D><M><S><S><V><S><P><S><S><T><L><K...
Catalyzes the conversion of 2-formylglutarate to (S)-2-hydroxymethylglutarate. Has very low activity with (S)-3-hydroxyisobutyrate.<BOP>
Q0QLF5
A9C2R2
BIOB_DELAS
Biotin synthase
Delftia
<M><T><A><C><S><T><T><P><T><T><S><A><T><S><A><Q><P><A><A><G><S><P><L><Q><W><H><A><R><P><S><K><S><D><T><L><P><F><E><G><A><W><S><V><Q><A><I><Q><E><L><L><D><K><P><F><M><D><L><M><F><Q><A><Q><S><V><H><R><E><H><W><P><A><G><D><I><E><L><A><T><L><L><S><V><K><T><G><G><C><P><E><N><C><G><Y><C><P><Q><A><A><E><F><D><T><G><V><K><A><E...
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.<BOP>
A9C2R2
Q2VZK3
KDSB_MAGSA
CMP-2-keto-3-deoxyoctulosonic acid synthase
Magnetospirillum
<M><A><E><L><T><P><I><I><V><I><P><A><R><M><Q><A><T><R><L><P><G><K><P><L><A><D><I><H><G><E><P><M><I><I><H><V><W><R><R><S><V><Q><A><G><L><G><P><V><V><V><A><C><S><E><A><E><V><F><D><A><V><H><A><H><G><G><Q><A><V><M><T><D><P><D><H><P><S><G><S><D><R><V><W><E><A><V><R><K><L><D><P><E><G><R><F><D><A><I><V><N><V><Q><G><D><L><P><T...
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.<BOP>
Q2VZK3
Q6NH02
AROC_CORDI
5-enolpyruvylshikimate-3-phosphate phospholyase
Corynebacterium
<M><L><R><W><T><T><A><G><E><S><H><G><Q><A><L><I><A><M><L><E><H><M><P><A><G><V><P><I><S><R><E><E><I><S><F><Q><L><G><R><R><R><L><G><F><G><R><G><A><R><M><K><F><E><A><D><E><V><S><I><L><G><G><V><R><H><G><Y><T><I><G><S><P><I><A><I><M><V><G><N><T><E><W><P><K><W><T><T><I><M><S><A><D><A><I><D><E><S><D><P><D><V><A><A><A><M><S><S...
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s...
Q6NH02
A4G4X3
PURT_HERAR
Phosphoribosylglycinamide formyltransferase 2
Herminiimonas
<M><N><K><S><N><T><I><S><R><I><G><T><P><L><T><H><N><A><T><K><V><M><L><L><G><S><G><E><L><G><K><E><V><I><I><S><L><Q><R><L><G><I><E><V><I><A><V><D><R><Y><A><N><A><P><G><H><Q><V><A><H><R><A><Y><V><I><D><M><T><D><G><V><A><L><A><A><L><I><N><Q><E><K><P><D><L><V><V><P><E><I><E><A><I><A><T><A><T><L><L><E><M><E><N><A><G><N><V><R...
Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.<BOP>
A4G4X3
A0KRM0
RS7_SHESA
30S ribosomal protein S7
Shewanella
<M><P><R><R><R><V><V><G><Q><R><K><I><L><P><D><P><K><F><H><S><E><L><L><A><K><F><I><N><V><I><M><Q><D><G><K><K><S><T><A><E><K><I><I><Y><K><A><L><D><V><I><A><E><K><K><G><A><N><H><L><D><V><L><E><A><A><L><D><N><V><R><P><S><V><E><V><K><S><R><R><V><G><G><S><T><Y><Q><V><P><C><E><V><R><P><V><R><R><N><A><L><A><M><R><W><L><V><E><A...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.<BOP>
A0KRM0
Q9A894
SSB_CAUVC
Single-stranded DNA-binding protein
Caulobacter
<M><A><G><S><V><N><K><V><I><L><V><G><N><L><G><A><D><P><E><I><R><S><L><G><S><G><D><R><V><A><N><L><R><I><A><T><S><E><T><W><R><D><R><S><S><G><E><R><K><E><K><T><E><W><H><R><V><V><I><F><N><D><N><L><V><K><V><A><E><Q><Y><L><R><K><G><S><T><V><Y><I><E><G><A><L><Q><T><R><K><W><T><D><N><T><G><Q><E><K><Y><S><T><E><I><V><L><Q><K><F...
Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.<BOP>
Q9A894
Q5PPX5
RN170_XENLA
RING-type E3 ubiquitin transferase RNF170
Xenopus
<M><A><D><N><Q><E><E><R><P><H><F><P><L><D><E><G><S><I><I><E><G><V><S><D><Q><V><I><V><V><V><L><L><S><F><V><A><V><G><S><L><I><Y><L><L><L><R><N><D><E><Q><N><I><H><P><E><N><Q><D><R><V><R><A><V><R><E><Q><L><Q><N><E><Q><E><T><P><A><P><P><R><P><Q><F><Y><S><D><M><T><C><P><V><C><L><Q><Q><A><T><F><P><V><E><T><N><C><G><H><L><F><C...
E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor (ITPR) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR turnover in resting cells.<BOP>
Q5PPX5
Q49SQ1
GPR33_HUMAN
Probable G-protein coupled receptor 33
Homo
<M><D><L><I><N><S><T><D><Y><L><I><N><A><S><T><L><V><R><N><S><T><Q><F><L><A><P><A><S><K><M><I><I><A><L><S><L><Y><I><S><S><I><I><G><T><I><T><N><G><L><Y><L><W><V><L><R><F><K><M><K><Q><T><V><N><T><L><L><F><F><H><L><I><L><S><Y><F><I><S><T><M><I><L><P><F><M><A><T><S><Q><L><Q><D><N><H><W><N><F><G><T><A><L><C><K><V><F><N><G><T...
Orphan receptor; could be a chemoattractant receptor.<BOP>
Q49SQ1
Q0P3L0
RPOA_OSTTA
Plastid-encoded RNA polymerase subunit alpha
Ostreococcus
<M><I><K><A><A><A><T><L><K><S><L><Q><Y><R><Q><N><S><L><T><D><C><Y><G><R><L><S><F><G><P><V><N><P><G><Q><G><L><T><I><G><N><T><L><R><R><I><L><L><N><D><L><P><G><I><G><V><I><G><A><E><I><N><G><V><Q><S><E><F><S><T><L><P><G><I><R><E><S><V><I><E><I><F><L><N><L><R><E><L><I><F><T><P><T><A><T><C><A><Q><K><V><K><Q><T><K><P><F><V><Y...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
Q0P3L0
A4SDU0
CYSD_CHLPM
Sulfate adenylate transferase
Chlorobium
<M><P><S><Y><R><L><S><H><L><K><Q><L><E><A><E><S><I><H><I><I><R><E><V><A><V><E><F><E><N><P><V><M><L><Y><S><I><G><K><D><S><S><V><M><V><R><L><A><E><K><A><F><Y><P><G><K><V><P><F><P><L><L><H><V><D><S><K><W><K><F><R><E><M><I><E><F><R><D><S><Y><A><R><E><N><N><W><G><L><I><V><H><S><N><E><E><A><F><A><D><G><V><G><P><F><S><H><G><S...
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysi...
A4SDU0
B0RB39
RL3_CLAMS
50S ribosomal protein L3
Clavibacter
<M><S><T><A><N><R><T><F><T><G><L><L><G><T><K><L><G><M><T><Q><V><W><D><E><N><N><K><L><I><P><V><T><V><V><Q><I><T><P><N><V><V><T><Q><V><R><T><P><E><V><D><G><Y><G><A><I><Q><I><A><Y><G><Q><I><D><P><R><K><A><D><K><P><S><T><G><H><F><D><K><A><G><V><T><P><R><R><H><L><T><E><V><R><T><A><D><F><A><E><Y><T><L><G><Q><E><I><T><V><G><A...
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP>
B0RB39
O29170
Y1095_ARCFU
Putative antitoxin AF_1095
Archaeoglobus
<M><P><K><I><I><E><A><I><Y><E><N><G><V><F><K><P><L><Q><K><V><D><L><K><E><G><E><R><I><K><L><R><I><E><E><G><I><L><D><V><I><K><K><Y><Q><G><K><F><K><L><T><E><K><D><I><E><K><F><L><E><E><R><R>
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.<BOP>
O29170
A0LLH2
YIDD_SYNFM
Putative membrane protein insertion efficiency factor
Syntrophobacter
<M><I><R><S><I><F><L><G><L><I><R><F><Y><Q><I><V><L><S><P><L><K><G><P><R><C><R><F><L><P><T><C><S><Q><Y><A><Y><E><A><I><E><R><Y><G><I><W><R><G><L><F><L><G><G><K><R><L><L><R><C><H><P><F><H><A><G><G><Y><D><P><V><P><R><P><S><A><N><N><H><P><S><R>
Could be involved in insertion of integral membrane proteins into the membrane.<BOP>
A0LLH2
A7FYL7
DNLJ_CLOB1
Polydeoxyribonucleotide synthase [NAD(+)]
Clostridium
<M><D><N><K><L><E><K><M><K><E><L><V><E><E><L><N><Q><Y><A><Y><E><Y><Y><V><L><D><N><P><S><I><S><D><K><E><Y><D><L><K><Y><D><E><L><V><I><L><E><K><K><T><E><V><T><L><P><Y><S><P><T><Q><R><V><G><D><K><I><L><G><E><F><S><K><Y><T><H><K><G><R><L><W><S><L><D><K><A><Q><N><M><E><Q><L><I><E><W><H><N><R><N><L><K><V><I><E><Q><Y><N><S><M...
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP>
A7FYL7
C0QYL1
ACP_BRAHW
Acyl carrier protein
Brachyspira
<M><A><L><I><D><E><I><K><D><V><V><A><N><Q><L><N><I><S><D><K><S><K><I><T><D><T><A><S><F><V><D><D><L><N><A><D><S><L><D><L><V><E><L><I><M><E><L><E><K><R><Y><E><I><K><I><P><Q><E><D><Q><E><K><I><K><N><V><A><D><A><A><K><Y><I><E><E><H><K><K>
Carrier of the growing fatty acid chain in fatty acid biosynthesis.<BOP>
C0QYL1
P60069
CLRB_IDEDE
Chlorate reductase iron-sulfur subunit
Ideonella
<M><S><Q><R><Q><V><A><Y><V><F><D><L><N><K><C><I><G><C><H><T><C><T><M><A><C><K><Q><L><W><T><N><R><D><G><R><E><Y><M><Y><W><N><N><V><E><T><R><P><G><K><G><Y><P><K><N><W><E><G><K><G><G><G><F><D><Q><E><G><K><L><K><T><N><G><I><I><P><I><M><A><D><Y><G><G><R><I><G><D><F><N><L><N><E><V><L><L><E><G><K><A><D><Q><V><V><P><H><E><K><A...
Electron transfer subunit of the terminal reductase during anaerobic growth on chlorate.<BOP>
P60069
C3P6Y3
RPOY_BACAA
Transcriptase subunit epsilon
Bacillus cereus group
<M><I><F><K><V><F><Y><Q><E><K><M><T><E><V><P><V><R><E><N><T><K><V><L><Y><L><E><A><T><S><E><K><D><V><R><T><K><L><N><K><F><A><Y><N><I><E><F><V><Q><S><V><T><G><N><H><L><E><Y><E><K><A><N><A><D><L><T><L><A><E><I><V>
A non-essential component of RNA polymerase (RNAP).<BOP>
C3P6Y3
B2V753
RL19_SULSY
50S ribosomal protein L19
unclassified Sulfurihydrogenibium
<M><H><Q><L><I><R><E><I><E><Q><K><Y><L><P><Q><D><I><P><E><F><K><V><G><D><T><V><R><L><H><L><K><V><K><E><G><E><K><E><R><T><Q><I><F><E><G><L><V><I><R><V><R><G><S><G><T><G><K><T><F><T><V><R><K><V><S><Y><G><V><G><M><E><R><I><F><P><I><A><C><P><S><I><Q><K><I><E><V><V><K><R><G><K><V><R><R><A><K><L><Y><Y><I><R><N><L><K><G><K><A...
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.<BOP>
B2V753
Q4K4U9
PQQD_PSEF5
Pyrroloquinoline quinone biosynthesis protein D
Pseudomonas
<M><S><F><D><R><S><K><T><P><R><W><R><P><G><Y><R><F><Q><Y><E><P><A><Q><K><G><H><V><L><L><Y><P><E><G><M><I><K><L><N><D><S><A><A><L><I><G><G><L><I><D><G><E><R><D><V><A><A><I><I><S><E><L><E><I><Q><F><P><G><V><A><E><L><G><E><D><I><E><Q><F><M><E><V><A><R><A><Q><H><W><I><E><L><A>
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.<BOP>
Q4K4U9
A0QWQ9
AROC_MYCS2
5-enolpyruvylshikimate-3-phosphate phospholyase
Mycolicibacterium
<M><L><R><W><T><T><A><G><E><S><H><G><R><A><L><V><A><M><L><E><G><M><V><A><G><V><P><I><T><S><E><E><I><G><A><Q><L><K><R><R><R><L><G><Y><G><R><G><A><R><M><K><F><E><Q><D><Q><V><T><M><L><A><G><V><R><H><G><L><T><L><G><G><P><I><A><I><E><I><G><N><T><E><W><P><K><W><E><S><V><M><S><P><D><P><V><D><P><A><D><L><D><V><A><R><N><A><P><L...
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s...
A0QWQ9
B5XI32
EFP_STRPZ
Elongation factor P
Streptococcus
<M><I><E><A><S><K><L><K><A><G><M><T><F><E><A><E><G><K><L><I><R><V><L><E><A><S><H><H><K><P><G><K><G><N><T><I><M><R><M><K><L><R><D><V><R><T><G><S><T><F><D><T><T><Y><R><P><D><E><K><F><E><Q><A><I><I><E><T><V><P><A><Q><Y><L><Y><K><M><D><D><T><A><Y><F><M><N><T><D><T><Y><D><Q><Y><E><I><P><V><A><N><V><E><Q><E><L><L><Y><I><L><E...
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP>
B5XI32
P0DOX0
C27C1_LITCT
All-trans retinol 3,4-desaturase
Lithobates
<M><L><W><Q><C><W><L><Q><Q><A><Q><R><M><R><M><M><M><K><A><L><L><R><F><R><A><T><R><L><D><S><E><M><M><G><G><W><R><R><G><A><Q><R><L><A><A><G><V><V><E><G><Q><R><T><L><P><Q><E><G><A><A><A><G><P><R><N><L><K><E><M><P><G><P><S><T><F><R><N><L><L><E><F><F><W><R><D><G><F><S><R><I><H><E><I><Q><Q><N><H><I><R><E><Y><G><R><I><F><K><S...
Efficiently catalyzes the conversion of all-trans retinol (also called vitamin A1, the precursor of 11-cis retinal) to 3,4-didehydroretinol (also called vitamin A2, the precursor of 11-cis 3,4-didehydroretinal), also acts on all-trans retinal and all-trans retinoic acid. The replacement of 11-cis retinal chromophore in...
P0DOX0
Q84L09
GONS2_ARATH
Protein GOLGI NUCLEOTIDE SUGAR TRANSPORTER 2
Arabidopsis
<M><S><A><V><K><L><E><A><I><V><C><H><E><P><D><E><S><E><L><S><H><L><S><D><N><G><S><K><T><K><N><G><V><V><F><Q><L><L><D><Q><K><S><S><E><H><R><W><F><S><E><R><F><L><R><W><R><R><R><Y><L><P><V><D><G><D><N><R><R><D><H><G><S><V><K><Q><S><G><P><L><V><S><G><A><A><Y><C><I><S><S><C><S><M><I><I><L><N><K><I><V><L><S><S><Y><N><F><N><A...
GDP-mannose transporter that may be involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.<BOP>
Q84L09
Q4R4Z1
SYNC_MACFA
Asparaginyl-tRNA synthetase 1
Macaca
<M><S><L><E><V><T><R><A><T><A><G><M><V><L><E><L><Y><V><S><D><R><E><G><S><D><A><T><G><D><G><T><K><E><K><P><F><K><T><G><L><K><A><L><M><T><V><G><K><E><P><F><P><T><I><Y><V><D><S><Q><K><E><N><E><R><W><N><V><I><S><K><S><Q><L><K><N><I><K><K><M><W><H><R><E><Q><M><K><S><E><S><R><E><K><K><E><A><E><D><S><L><R><R><E><K><N><L><E><E...
Catalyzes the attachment of asparagine to tRNA(Asn) in a two-step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn). In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells. Ha...
Q4R4Z1
Q0SU39
KUP_CLOPS
Probable potassium transport system protein kup
Clostridium
<M><S><T><N><K><S><S><I><E><K><I><T><L><G><S><F><L><I><A><L><G><V><V><Y><G><D><I><G><T><S><P><L><Y><V><M><K><S><I><I><N><G><N><G><G><L><E><S><I><T><P><D><F><I><L><G><V><L><S><L><I><F><W><T><M><T><L><L><T><T><I><K><Y><V><L><I><T><L><K><A><D><N><K><G><E><G><G><I><F><S><L><Y><T><L><I><R><R><R><A><K><W><L><I><I><P><A><M><V...
Transport of potassium into the cell.<BOP>
Q0SU39
A4T8Q2
CYSD_MYCGI
Sulfate adenylate transferase
Mycolicibacterium
<M><T><A><T><D><E><L><T><H><N><A><G><R><Y><E><L><S><H><L><R><A><L><E><A><E><A><I><H><I><I><R><E><V><A><A><E><F><E><R><P><V><L><L><F><S><G><G><K><D><S><I><V><M><L><H><L><A><V><K><A><F><R><P><G><R><L><P><F><P><V><M><H><V><D><T><G><H><N><F><D><E><V><L><Q><A><R><D><E><L><V><A><E><T><G><V><R><L><V><V><A><K><V><Q><D><D><I><D...
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysi...
A4T8Q2
B7IHV6
RL14_THEAB
50S ribosomal protein L14
Thermosipho
<M><I><I><N><E><S><Y><L><N><V><A><D><N><S><G><A><K><L><L><R><V><I><R><V><M><G><G><S><R><R><K><W><G><T><V><G><D><V><V><V><C><S><V><R><D><A><V><P><N><G><D><L><K><K><G><D><V><V><K><A><V><I><V><R><T><K><K><E><I><R><R><P><D><G><T><Y><I><R><F><D><D><N><A><A><V><V><L><D><K><Y><N><E><P><K><G><T><R><V><F><G><P><V><A><K><E><L><R...
Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.<BOP>
B7IHV6
Q3YW48
NIKE_SHISS
Nickel import ATP-binding protein NikE
Shigella
<M><T><L><L><N><V><S><G><L><S><H><H><Y><A><H><G><G><F><N><G><K><H><Q><H><Q><A><V><L><N><N><V><S><L><T><L><K><S><G><E><T><V><A><L><L><G><R><S><G><C><G><K><S><T><L><A><R><L><L><V><G><L><E><S><P><A><Q><G><N><I><S><W><R><G><E><P><L><A><K><L><N><R><A><Q><R><K><A><F><R><R><D><I><Q><M><V><F><Q><D><S><I><S><A><V><N><P><R><K><T...
Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system.<BOP>
Q3YW48
Q95J82
FSHB_MONDO
Follitropin beta chain
Monodelphis
<M><K><T><A><Q><F><Y><I><F><F><F><C><W><K><A><I><W><C><N><G><C><V><L><T><N><I><T><I><S><V><E><R><E><E><C><E><F><C><I><S><I><N><T><T><W><C><S><G><Y><C><H><T><R><D><L><V><Y><K><E><P><I><R><P><N><I><Q><K><A><C><T><F><R><E><F><V><Y><E><T><M><S><L><P><G><C><A><N><Q><A><D><S><L><Y><S><Y><P><V><A><T><A><C><H><C><G><S><C><D><T...
Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and sperma...
Q95J82
Q0BVS2
KDPA_GRABC
Potassium-translocating ATPase A chain
Granulibacter
<M><S><M><A><G><W><I><T><I><G><I><F><F><L><C><V><L><A><L><T><R><P><L><G><G><F><L><V><S><V><L><E><G><R><R><T><F><L><S><P><I><L><G><P><V><E><R><A><L><Y><R><F><S><G><V><R><P><E><E><E><Q><S><W><S><H><Y><A><L><A><L><L><S><F><K><I><V><C><F><V><A><V><Y><A><I><L><R><L><Q><A><Y><L><P><L><N><P><A><G><Q><G><S><V><A><P><D><L><A><Y...
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel....
Q0BVS2
Q8IZ16
SACDR_HUMAN
Sperm acrosome developmental regulator
Homo
<M><V><V><V><M><K><F><F><R><W><V><R><R><A><W><Q><R><I><I><S><W><V><F><F><W><R><Q><K><I><K><P><T><I><S><G><H><P><D><S><K><K><H><S><L><K><K><M><E><K><T><L><Q><V><V><E><T><L><R><L><V><E><L><P><K><E><A><K><P><K><L><G><E><S><P><E><L><A><D><P><C><V><L><A><K><T><T><E><E><T><E><V><E><L><G><Q><Q><G><Q><S><L><L><Q><L><P><R><T><A...
May play a role in acrosome formation and nucleus shaping during spermiogenesis.<BOP>
Q8IZ16
Q9KF78
GUAA_HALH5
Glutamine amidotransferase
Halalkalibacterium (ex Joshi et al. 2022)
<M><E><Q><L><S><E><E><M><I><V><V><L><D><F><G><G><Q><Y><N><Q><L><I><T><R><R><I><R><D><L><G><V><Y><S><E><L><H><P><N><T><I><T><A><E><Q><L><K><E><M><K><P><K><G><I><I><F><S><G><G><P><N><S><A><Y><A><E><G><A><P><K><C><D><P><A><I><F><D><L><G><V><P><I><L><G><I><C><Y><G><M><Q><L><M><T><Q><H><F><G><G><K><V><D><A><A><E><H><R><E><Y...
Catalyzes the synthesis of GMP from XMP.<BOP>
Q9KF78
Q0Q2J8
MNHC2_STAAU
Putative NADH-ubiquinone oxidoreductase subunit mnhC2
Staphylococcus
<M><N><L><I><L><L><L><V><I><G><F><L><V><F><I><G><T><Y><M><I><L><S><I><N><L><I><R><I><V><I><G><I><S><I><Y><T><H><A><G><N><L><I><I><M><S><M><G><T><Y><G><S><S><R><S><E><P><L><I><T><G><G><N><Q><L><F><V><D><P><L><L><Q><A><I><V><L><T><A><I><V><I><G><F><G><M><T><A><F><L><L><V><L><V><Y><R><T><Y><K><V><T><K><E><D><E><I><E><G><L...
Expression of the mnh2 operon in E.coli is not able to catalyze Na(+)Li(+)/H(+) antiport. It does however confer higher growth rates than the control strain at up to pH 9.5. The operon may encode an NADH-ubiquinone oxidoreductase.<BOP>
Q0Q2J8
E7CLN8
SCX16_RHOJU
Putative alpha-neurotoxin RjAa16
Rhopalurus
<K><E><G><Y><P><V><D><W><G><N><C><K><Y><E><C><M><S><D><A><Y><C><K><D><L><C><V><D><R><K><A><K><S><G><Y><C><Y><K><L><N><W><F><C><Y><C><E><G><L><P><D><D><S><P><I><K><T><N><G><H><C><R><P><G><G><R><R><K>
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.<BOP>
E7CLN8
Q9ZPV9
SY112_ARATH
Syntaxin-112
Arabidopsis
<M><N><D><L><M><T><K><S><F><L><S><Y><V><E><L><K><K><Q><A><R><T><D><M><E><S><D><R><D><L><E><K><G><E><D><F><N><F><D><F><S><P><A><D><E><E><N><L><S><G><F><F><Q><E><I><E><T><I><K><T><L><I><E><E><I><T><H><L><L><L><D><L><Q><N><L><N><E><E><T><K><S><T><H><S><T><K><I><L><R><G><L><R><D><R><M><E><S><N><I><V><T><I><S><R><K><A><N><T...
Vesicle trafficking protein that functions in the secretory pathway.<BOP>
Q9ZPV9
A7X5F5
RS3_STAA1
30S ribosomal protein S3
Staphylococcus
<M><G><Q><K><I><N><P><I><G><L><R><V><G><I><I><R><D><W><E><A><K><W><Y><A><E><K><D><F><A><S><L><L><H><E><D><L><K><I><R><K><F><I><D><N><E><L><K><E><A><S><V><S><H><V><E><I><E><R><A><A><N><R><I><N><I><A><I><H><T><G><K><P><G><M><V><I><G><K><G><G><S><E><I><E><K><L><R><N><K><L><N><A><L><T><D><K><K><V><H><I><N><V><I><E><I><K><K...
Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.<BOP>
A7X5F5
A4SC23
RECF_CHLPM
DNA replication and repair protein RecF
Chlorobium
<M><R><L><R><S><I><Q><F><E><N><F><R><N><H><R><S><F><S><F><E><P><E><D><G><I><N><L><I><Y><G><Q><N><G><S><G><K><T><S><I><L><E><G><I><H><Y><C><A><L><T><K><G><F><V><S><A><A><D><G><E><C><L><S><F><S><A><G><Y><F><L><L><T><A><L><F><E><S><S><S><G><I><E><T><A><V><R><L><S><Y><T><K><E><S><G><K><K><L><Q><I><D><G><N><E><L><K><P><F><S...
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.<BOP>
A4SC23
B2JFI9
FABH_PARP8
3-oxoacyl-[acyl-carrier-protein] synthase III
Paraburkholderia
<M><A><Q><S><T><T><Y><S><R><V><L><G><T><G><S><Y><L><P><P><N><R><V><S><N><Q><D><L><A><A><R><L><A><K><Q><G><I><E><T><S><D><E><W><I><V><A><R><T><G><I><H><A><R><H><F><A><E><P><D><V><T><T><S><D><L><A><L><I><A><S><Q><R><A><I><E><A><A><D><V><D><P><Q><A><I><D><L><I><I><V><A><T><S><T><P><D><F><V><F><P><S><T><A><C><L><L><Q><N><K...
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-A...
B2JFI9
Q8D4B4
RLMC_VIBVU
23S rRNA(m5U747)-methyltransferase
Vibrio
<M><S><C><P><Y><F><E><Q><K><S><C><T><S><C><T><H><M><N><T><P><Y><S><Q><Q><L><E><T><K><D><N><A><L><R><S><L><F><S><D><V><E><Q><S><A><W><L><A><P><V><Q><S><D><S><M><H><C><R><N><K><A><K><M><V><A><L><G><A><A><H><Q><P><T><L><G><I><E><S><V><Q><D><G><T><P><I><S><L><V><H><C><P><L><Y><T><Q><E><S><Q><E><L><L><A><Y><L><Q><E><W><I><R...
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.<BOP>
Q8D4B4
Q9ZNE0
HACA_THET2
Homoaconitate hydratase
Thermus
<M><G><Q><T><L><A><E><K><I><L><S><H><K><V><G><R><P><V><R><A><G><E><L><V><V><V><E><V><D><Q><V><M><V><V><D><S><I><A><G><S><F><F><K><R><L><E><Y><L><E><A><T><P><R><Y><P><E><R><V><S><I><V><I><D><H><V><A><P><A><A><N><L><E><V><A><K><A><Q><K><E><I><R><E><W><G><K><R><H><G><I><R><V><F><D><V><G><R><G><V><C><H><Q><V><L><I><E><E><G...
Catalyzes the reversible hydration of cis-homoaconitate ((Z)-but-1-ene-1,2,4-tricarboxylate) to homoisocitrate ((1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate). Can catalyze neither the dehydration of (R)-homocitrate ((2R)-2-hydroxybutane-1,2,4-tricarboxylate) into cis-homoaconitate in vitro, nor the reverse reaction. Is...
Q9ZNE0
A1US27
DAPA_BARBK
4-hydroxy-tetrahydrodipicolinate synthase
Bartonella
<M><L><K><G><A><L><T><A><L><I><T><P><F><N><E><N><G><S><V><D><E><E><T><F><C><N><F><I><E><W><Q><I><T><Q><G><I><D><G><L><I><P><A><G><T><T><G><E><S><P><T><L><S><H><E><E><H><K><K><V><I><E><L><C><V><E><K><V><A><K><R><V><P><V><V><A><G><A><G><S><N><S><T><D><E><A><V><E><L><A><Q><H><A><K><K><A><G><A><D><A><V><L><V><V><T><P><Y><Y...
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).<BOP>
A1US27
Q01631
CYAA_NEUCR
Crisp-1
Neurospora
<M><T><R><N><D><G><G><S><R><Y><S><S><I><D><S><A><Q><S><S><I><T><A><K><P><F><P><L><T><P><T><S><S><L><G><S><S><M><T><R><P><L><S><P><S><L><Q><A><G><S><S><S><S><N><G><G><H><N><V><S><R><S><A><S><Q><G><A><R><R><P><A><P><T><R><L><K><T><D><D><G><T><Q><F><A><S><R><S><S><R><D><F><E><S><S><Q><S><Q><S><Q><P><S><H><T><Q><T><R><S><H...
Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.<BOP>
Q01631
Q7U8U7
ATPB_PARMW
F-ATPase subunit beta
Parasynechococcus marenigrum
<M><V><A><S><A><P><A><S><A><G><T><K><G><V><I><R><Q><V><I><G><P><V><L><D><V><E><F><P><A><G><K><L><P><K><I><Y><N><A><L><R><V><E><T><K><N><T><A><G><Q><D><V><A><L><T><A><E><V><Q><Q><L><L><G><D><H><R><V><R><A><V><A><M><S><G><T><D><G><L><V><R><G><M><E><I><A><D><T><G><A><P><I><S><V><P><V><G><E><A><T><L><G><R><I><F><N><V><L><G...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP>
Q7U8U7
Q57816
FTSZ1_METJA
Cell division protein FtsZ 1
Methanocaldococcus
<M><K><F><L><K><N><V><L><E><E><G><S><K><L><E><E><F><N><E><L><E><L><S><P><E><D><K><E><L><L><E><Y><L><Q><Q><T><K><A><K><I><T><V><V><G><C><G><G><A><G><N><N><T><I><T><R><L><K><M><E><G><I><E><G><A><K><T><V><A><I><N><T><D><A><Q><Q><L><I><R><T><K><A><D><K><K><I><L><I><G><K><K><L><T><R><G><L><G><A><G><G><N><P><K><I><G><E><E><A...
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new ce...
Q57816
A6VQH8
ISPH_ACTSZ
4-hydroxy-3-methylbut-2-enyl diphosphate reductase
Actinobacillus
<M><K><I><I><L><A><N><P><R><G><F><C><A><G><V><D><R><A><I><S><I><V><E><L><A><L><E><I><H><G><A><P><I><Y><V><R><H><E><V><V><H><N><R><F><V><V><N><G><L><R><E><R><G><A><V><F><V><E><E><L><D><E><V><P><D><G><A><I><V><I><F><S><A><H><G><V><S><Q><A><V><R><Q><E><A><K><R><R><N><L><K><V><F><D><A><T><C><P><L><V><T><K><V><H><M><Q><V><A...
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.<BOP>
A6VQH8
B1WQH2
MTNA_CROS5
S-methyl-5-thioribose-1-phosphate isomerase
Crocosphaera subtropica
<M><N><T><I><Y><P><V><I><W><S><N><N><K><V><L><L><I><D><Q><T><S><L><P><S><R><Y><T><L><V><E><I><S><R><Y><E><D><M><A><K><A><I><K><T><M><I><V><R><G><A><P><A><I><G><V><A><A><A><Y><G><M><Y><L><G><A><R><D><I><Q><T><Q><D><R><E><T><F><L><K><H><L><D><K><I><A><Q><I><L><R><Q><T><R><P><T><A><V><N><L><F><W><A><I><S><R><M><L><K><T><A...
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).<BOP>
B1WQH2
Q9UI95
MD2L2_HUMAN
REV7 homolog
Homo
<M><T><T><L><T><R><Q><D><L><N><F><G><Q><V><V><A><D><V><L><C><E><F><L><E><V><A><V><H><L><I><L><Y><V><R><E><V><Y><P><V><G><I><F><Q><K><R><K><K><Y><N><V><P><V><Q><M><S><C><H><P><E><L><N><Q><Y><I><Q><D><T><L><H><C><V><K><P><L><L><E><K><N><D><V><E><K><V><V><V><V><I><L><D><K><E><H><R><P><V><E><K><F><V><F><E><I><T><Q><P><P><L...
Adapter protein able to interact with different proteins and involved in different biological processes . Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis . Transl...
Q9UI95
Q05354
HPCD_ECOLX
5-carboxymethyl-2-hydroxymuconic acid isomerase
Escherichia
<M><P><H><F><I><V><E><C><S><D><N><I><R><E><E><A><D><L><P><G><L><F><A><K><V><N><P><T><L><A><A><T><G><I><F><P><L><A><G><I><R><S><R><V><H><W><V><D><T><W><Q><M><A><D><G><Q><H><D><Y><A><S><V><H><M><T><L><K><I><G><A><G><R><S><L><E><S><R><Q><Q><A><G><E><M><L><F><E><L><I><K><T><H><F><A><A><L><M><E><S><R><L><L><A><L><S><F><E><I...
Transforms 5-carboxymethyl-2-hydroxy-muconic acid (CHM) into 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid (OPET).<BOP>
Q05354
Q4KBE3
FABV_PSEF5
Enoyl-[acyl-carrier-protein] reductase [NADH]
Pseudomonas
<M><V><I><K><P><R><V><R><G><F><I><C><V><T><T><H><P><V><G><C><E><A><N><V><K><Q><Q><I><D><Y><V><T><Q><Q><G><A><I><D><A><G><P><K><N><V><L><V><L><G><A><S><T><G><Y><G><L><A><A><R><I><T><A><A><F><G><C><G><A><N><T><L><G><V><F><F><E><R><G><S><V><D><G><K><L><G><T><A><G><W><Y><N><T><A><A><F><H><K><F><A><E><E><K><G><L><Y><A><K><S...
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).<BOP>
Q4KBE3
A1RRT7
PELO_PYRIL
Protein pelota homolog
Pyrobaculum
<M><R><Y><E><V><D><T><K><R><R><I><I><K><L><V><P><E><R><E><E><D><L><Y><F><I><Y><L><L><I><D><K><G><D><I><I><R><G><W><T><V><R><E><Y><K><P><D><G><V><K><E><G><E><R><I><K><I><Y><L><A><I><K><V><E><S><L><E><Y><H><K><F><R><G><S><L><R><I><R><G><T><V><V><E><V><Q><D><G><I><E><G><V><K><G><R><R><H><T><F><D><V><T><P><G><R><E><I><E><I...
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.<BOP>
A1RRT7
Q5SHY1
Y1599_THET8
Nucleoid-associated protein TTHA1599
Thermus
<M><N><F><Q><K><L><L><K><E><A><Q><K><A><Q><K><K><A><A><E><V><Q><E><R><L><E><R><M><T><V><V><G><S><A><Q><G><L><V><E><V><E><A><N><G><H><G><K><I><L><A><L><R><L><K><P><E><A><L><K><A><F><Q><D><D><P><E><G><L><E><D><L><L><L><V><A><I><Q><D><A><Q><T><K><A><H><E><L><S><E><K><E><M><A><K><E><L><G><G><V><G><Q><M><L><G><K><L><F>
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP>
Q5SHY1
Q9FJ00
RSL1_ARATH
bHLH transcription factor bHLH086
Arabidopsis
<M><S><L><I><N><E><H><C><N><E><R><N><Y><I><S><T><P><N><S><S><E><D><L><S><S><P><Q><N><C><G><L><D><E><G><A><S><A><S><S><S><S><T><I><N><S><D><H><Q><N><N><Q><G><F><V><F><Y><P><S><G><E><T><I><E><D><H><N><S><L><M><D><F><N><A><S><S><F><F><T><F><D><N><H><R><S><L><I><S><P><V><T><N><G><G><A><F><P><V><V><D><G><N><M><S><Y><S><Y><D...
Transcription factor that is specifically required for the development of root hairs . Acts with RHD6 to positively regulate root hair development . Acts downstream of genes that regulate epidermal pattern formation, such as GL2 . Acts with RHD6 as transcription factor that integrates a jasmonate (JA) signaling pathway...
Q9FJ00
A7FGK6
AROC_YERP3
5-enolpyruvylshikimate-3-phosphate phospholyase
Yersinia
<M><A><G><N><S><I><G><Q><F><F><R><V><T><T><F><G><E><S><H><G><I><A><L><G><C><I><I><D><G><V><P><P><G><I><P><I><T><E><A><D><I><Q><L><D><L><D><R><R><R><P><G><T><S><R><Y><T><T><Q><R><R><E><L><D><Q><V><R><I><L><S><G><V><F><E><G><V><T><T><G><T><S><I><G><L><M><I><E><N><T><D><Q><R><S><Q><D><Y><S><A><I><K><D><V><F><R><P><G><H><A...
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s...
A7FGK6
P41181
AQP2_HUMAN
Water channel protein for renal collecting duct
Homo
<M><W><E><L><R><S><I><A><F><S><R><A><V><F><A><E><F><L><A><T><L><L><F><V><F><F><G><L><G><S><A><L><N><W><P><Q><A><L><P><S><V><L><Q><I><A><M><A><F><G><L><G><I><G><T><L><V><Q><A><L><G><H><I><S><G><A><H><I><N><P><A><V><T><V><A><C><L><V><G><C><H><V><S><V><L><R><A><A><F><Y><V><A><A><Q><L><L><G><A><V><A><G><A><A><L><L><H><E><I...
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient . Plays an essential role in renal water homeostasis .<BOP>
P41181
Q7M915
MNTP2_WOLSU
Putative manganese efflux pump MntP 2
Wolinella
<M><I><E><L><T><A><L><A><I><A><L><S><M><D><A><V><A><V><S><I><A><L><G><S><K><C><E><E><E><I><R><Q><L><A><L><K><A><G><G><F><F><G><V><A><Q><M><V><M><P><L><L><G><F><Y><L><G><V><Q><L><H><D><Y><I><G><G><I><H><H><W><V><A><L><G><V><L><G><F><L><G><L><K><M><I><R><E><A><T><Q><G><E><K><E><L><A><L><S><S><H><P><S><S><S><K><L><L><L><L...
Probably functions as a manganese efflux pump.<BOP>
Q7M915
B1KHI4
THIC_SHEWM
Thiamine biosynthesis protein ThiC
Shewanella
<M><S><N><R><R><Q><T><R><A><Q><A><Q><Q><F><I><D><T><L><T><P><L><Q><H><P><N><S><E><K><V><Y><L><T><G><S><R><E><D><L><R><V><G><M><R><Q><I><L><Q><S><D><T><L><V><G><G><T><E><A><D><P><I><L><E><S><N><P><P><L><K><V><Y><D><C><A><G><P><Y><S><D><P><D><A><E><I><N><V><R><A><G><L><N><K><F><R><Q><S><W><I><E><E><R><A><D><T><E><Q><L><A...
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP>
B1KHI4
Q8SWN8
ACT_ENCCU
Actin
Encephalitozoon
<M><S><E><I><V><Q><A><L><V><I><D><I><G><S><G><V><V><K><S><G><F><A><G><D><D><A><P><R><A><V><F><P><S><I><V><G><F><P><K><H><K><G><V><M><V><G><M><G><Q><K><D><A><Y><V><G><D><E><A><Q><T><K><R><G><I><L><H><I><K><Y><P><I><E><H><G><I><V><N><N><W><D><D><M><E><K><I><W><H><H><T><F><Y><N><E><L><R><V><A><P><E><E><H><P><V><L><L><T><E...
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.<BOP>
Q8SWN8
B2SG51
KDSB_FRATM
CMP-2-keto-3-deoxyoctulosonic acid synthase
Francisella
<M><A><N><I><H><I><V><I><P><A><R><L><K><S><T><R><L><P><N><K><M><L><A><D><I><A><G><K><P><M><I><Q><R><V><Y><E><Q><V><T><K><S><K><F><D><S><I><I><I><A><T><D><S><Q><K><I><K><D><I><A><E><S><F><D><A><K><V><V><L><T><R><D><D><H><Q><S><G><T><D><R><I><A><E><A><V><T><K><L><G><F><A><D><E><D><I><V><V><N><V><Q><G><D><E><P><L><I><P><I...
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.<BOP>
B2SG51
B1IMD7
SYD_CLOBK
Aspartyl-tRNA synthetase
Clostridium
<M><G><E><A><L><R><G><L><K><R><T><I><M><C><G><E><S><R><E><N><N><I><G><E><K><V><T><V><M><G><W><V><Q><R><K><R><N><L><G><G><L><I><F><V><D><L><R><D><R><T><G><I><M><Q><I><V><F><G><E><E><I><N><K><E><A><F><E><K><S><D><N><V><K><S><E><Y><C><I><A><V><T><G><E><I><V><K><R><Q><S><P><N><N><D><M><E><T><G><A><V><E><L><K><G><E><D><I><K...
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).<BOP>
B1IMD7
Q3ZBG8
MRNIP_BOVIN
MRN-interacting protein
Bos
<M><A><P><P><Q><Q><A><R><V><L><R><C><C><C><C><S><L><F><Q><A><H><Q><V><K><K><S><L><K><W><T><C><K><A><C><G><K><K><Q><S><F><L><Q><A><Y><G><E><G><S><G><A><D><C><R><R><H><V><Q><K><L><N><L><L><Q><G><Q><I><S><E><M><S><L><R><S><L><G><E><S><I><S><A><N><E><E><E><N><V><G><P><W><Q><A><A><R><A><S><P><Q><E><T><L><Q><P><S><K><N><R><W...
Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.<BOP>
Q3ZBG8
B7NPX2
HEM6_ECO7I
Oxygen-dependent coproporphyrinogen-III oxidase
Escherichia
<M><K><P><D><A><H><L><V><K><Q><F><L><L><N><L><Q><D><T><I><C><Q><Q><L><T><A><V><D><G><A><E><F><V><E><D><S><W><Q><R><E><A><G><G><G><G><R><S><R><V><L><R><N><G><G><V><F><E><Q><A><G><V><N><F><S><H><V><H><G><D><A><M><P><A><S><A><T><A><H><R><P><E><L><A><G><R><S><F><E><A><M><G><V><S><L><V><V><H><P><H><N><P><Y><V><P><T><S><H><A...
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.<BOP>
B7NPX2
Q5PNA5
ARNC_SALPA
Undecaprenyl-phosphate Ara4FN transferase
Salmonella
<M><F><D><A><A><P><I><K><K><V><S><V><V><I><P><V><Y><N><E><Q><E><S><L><P><E><L><I><R><R><T><T><A><A><C><E><S><L><G><K><A><W><E><I><L><L><I><D><D><G><S><S><D><S><S><A><E><L><M><V><K><A><S><Q><E><A><D><S><H><I><I><S><I><L><L><N><R><N><Y><G><Q><H><A><A><I><M><A><G><F><S><H><V><S><G><D><L><I><I><T><L><D><A><D><L><Q><N><P><P...
Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.<BOP>
Q5PNA5
Q7NJA4
SYDND_GLOVI
Non-discriminating aspartyl-tRNA synthetase
Gloeobacter
<M><R><S><D><Y><C><G><T><L><R><S><E><H><I><G><K><T><V><S><L><Y><G><W><I><D><G><W><R><D><H><G><G><V><I><F><L><D><L><R><D><Y><T><G><I><V><Q><I><V><A><D><P><Q><R><T><P><E><S><Y><H><L><A><S><S><L><R><N><E><Y><V><V><R><V><E><G><R><V><S><A><R><P><E><H><S><L><N><P><R><L><S><T><G><T><V><E><V><Y><A><D><T><L><A><V><L><N><R><A><E...
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).<BOP>
Q7NJA4
Q9H2W1
M4A6A_HUMAN
Four-span transmembrane protein 3
Homo
<M><T><S><Q><P><V><P><N><E><T><I><I><V><L><P><S><N><V><I><N><F><S><Q><A><E><K><P><E><P><T><N><Q><G><Q><D><S><L><K><K><H><L><H><A><E><I><K><V><I><G><T><I><Q><I><L><C><G><M><M><V><L><S><L><G><I><I><L><A><S><A><S><F><S><P><N><F><T><Q><V><T><S><T><L><L><N><S><A><Y><P><F><I><G><P><F><F><F><I><I><S><G><S><L><S><I><A><T><E><K...
May be involved in signal transduction as a component of a multimeric receptor complex.<BOP>
Q9H2W1
C4LJH6
ILVC_CORK4
Ketol-acid reductoisomerase type I
Corynebacterium
<M><A><I><K><T><Y><Y><D><D><D><A><D><L><S><I><I><Q><G><R><K><V><A><V><I><G><Y><G><S><Q><G><H><A><H><A><K><C><L><R><D><S><G><V><E><V><R><I><G><L><R><E><G><S><K><S><A><E><K><A><K><E><A><G><F><E><V><L><S><N><A><E><A><A><E><W><A><D><L><I><M><I><L><A><P><D><T><S><Q><I><A><I><F><E><K><E><I><E><P><H><L><K><D><G><D><A><I><F><F...
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu...
C4LJH6
Q56209
MOAD_SYNE7
Sulfur carrier protein MoaD
Synechococcus
<M><T><T><T><I><T><L><I><C><F><G><G><L><A><A><L><S><P><E><G><Q><P><M><P><L><E><L><D><L><P><A><T><A><A><D><L><K><V><A><I><A><R><A><C><D><L><M><P><D><S><A><L><A><Q><L><L><Q><K><S><A><I><G><S><E><T><R><I><Y><I><D><S><D><L><I><P><A><S><L><S><H><L><A><L><L><P><P><V><S><G><G>
Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin.<BOP>
Q56209
A0A1D8PLC9
RL20B_CANAL
60S ribosomal protein L20-B
Candida
<M><S><R><L><N><E><Y><Q><V><I><G><R><N><L><P><T><E><S><V><P><E><P><K><L><F><R><M><R><I><F><A><P><N><T><V><V><A><K><S><R><Y><W><Y><F><L><Q><K><L><H><K><V><K><K><A><S><G><E><I><V><S><V><N><I><I><S><E><A><K><P><T><K><V><K><T><F><G><I><W><L><R><Y><E><S><R><S><G><I><H><N><M><Y><K><E><Y><R><D><V><T><R><V><G><A><V><E><T><M><Y...
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosom...
A0A1D8PLC9
Q74BP0
MUTL_GEOSL
DNA mismatch repair protein MutL
Geobacter
<M><P><H><R><I><R><I><L><P><E><I><L><T><N><K><I><A><A><G><E><V><V><E><R><P><A><S><V><V><K><E><L><V><E><N><A><L><D><A><G><C><G><E><I><I><V><E><I><E><G><G><G><R><R><L><I><R><I><T><D><D><G><C><G><M><S><R><E><D><A><L><M><A><L><E><R><H><A><T><S><K><I><A><T><D><D><D><L><F><S><L><A><T><L><G><F><R><G><E><A><L><P><S><V><A><S><V...
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part ...
Q74BP0
O88422
GALT5_RAT
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5
Rattus
<M><N><K><I><R><K><F><F><R><G><S><G><R><V><L><A><F><I><F><V><A><S><V><I><W><L><L><F><D><M><A><A><L><R><L><S><F><S><E><I><N><T><G><I><L><K><E><D><I><M><R><R><E><Q><T><G><F><R><V><E><A><D><Q><M><T><I><L><S><P><S><S><R><G><M><R><P><P><R><N><G><A><G><G><K><E><S><F><R><K><A><E><N><R><V><L><K><V><E><E><N><V><D><Q><V><Q><R><K...
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward EA2 peptide substrate, but has a weak activity toward Muc2, Muc1b, rMuc-2 or mG-Muc substrates.<BOP>
O88422
Q72EF4
NRFH_DESVH
Cytochrome c-type protein NrfH
Desulfovibrio
<M><S><E><E><K><S><R><N><G><P><A><R><L><K><L><V><L><G><G><A><T><L><G><V><V><A><L><A><T><V><A><F><G><M><K><Y><T><D><Q><R><P><F><C><T><S><C><H><I><M><N><P><V><G><V><T><H><K><L><S><G><H><A><N><I><S><C><N><D><C><H><A><P><H><N><L><L><A><K><L><P><F><K><A><I><A><G><A><R><D><V><Y><M><N><T><L><G><H><P><G><D><L><I><L><A><G><M><E...
Electron donor subunit of the cytochrome c nitrite reductase holocomplex NrfHA. Acquires electrons from the menaquinone pool and mediates their transfer to the catalytic subunit NrfA in an anaerobic respiratory process of nitrite . The other biological function of the NrfHA holocomplex is to detoxify nitrite . This fun...
Q72EF4
Q6AAW5
DTD_CUTAK
Gly-tRNA(Ala) deacylase
Cutibacterium
<M><R><V><V><I><Q><R><A><T><S><A><E><V><V><V><E><G><R><T><V><G><S><L><T><T><P><G><L><V><V><L><V><G><V><T><G><T><D><T><A><T><T><A><E><K><L><A><E><K><V><W><G><L><R><I><L><S><E><E><K><S><A><S><D><L><N><A><P><L><L><V><V><S><Q><F><T><L><Y><A><S><T><R><K><G><R><R><P><S><W><S><A><A><A><P><G><P><V><S><E><P><L><V><D><H><F><V><T...
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By rec...
Q6AAW5
Q2VPG3
SDA1_XENLA
SDA1 domain-containing protein 1
Xenopus
<M><S><G><R><N><N><N><K><L><P><T><N><L><P><Q><L><Q><N><L><I><K><R><D><P><A><S><Y><R><E><E><F><L><Q><Q><Y><K><H><Y><L><S><V><I><E><I><F><K><L><Q><P><D><K><P><N><K><D><L><S><T><L><V><M><F><M><A><Q><T><A><H><C><F><Q><Q><Y><L><E><D><F><P><E><Q><L><K><S><L><L><C><T><H><H><T><V><M><D><P><D><Q><R><M><T><L><C><K><A><L><I><M><L...
Required for 60S pre-ribosomal subunits export to the cytoplasm.<BOP>
Q2VPG3
C4XLW8
RS12_SOLM1
30S ribosomal protein S12
Solidesulfovibrio
<M><P><T><I><N><Q><L><I><R><K><E><R><A><K><V><S><K><R><R><K><T><P><A><L><Q><A><C><P><Q><R><R><G><V><C><T><R><V><Y><T><T><T><P><K><K><P><N><S><A><L><R><K><V><A><R><V><R><L><T><N><G><I><E><V><T><S><Y><I><P><G><E><G><H><N><L><Q><E><H><S><V><V><M><I><R><G><G><R><V><K><D><L><P><G><V><R><Y><H><I><I><R><G><T><L><D><T><S><G><V...
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com...
C4XLW8
B4S6Q8
MURC_PROA2
UDP-N-acetylmuramoyl-L-alanine synthetase
Prosthecochloris
<M><E><L><G><K><T><K><C><V><H><I><V><G><I><G><G><A><G><M><S><A><I><A><E><L><L><L><K><S><G><F><T><V><T><G><S><D><L><S><S><G><E><V><T><D><K><L><S><E><L><G><A><E><V><Y><K><G><H><S><E><G><N><V><G><A><C><D><V><V><V><Y><S><S><A><V><R><P><E><S><N><V><E><I><L><A><A><E><K><K><G><I><P><V><I><K><R><D><E><M><L><G><E><L><M><R><F><R...
Cell wall formation.<BOP>
B4S6Q8
Q03UT5
RL9_LEUMM
50S ribosomal protein L9
Leuconostoc
<M><K><V><V><F><L><E><D><V><K><G><R><G><K><K><G><E><I><K><E><V><P><D><G><Y><A><N><N><F><L><I><K><N><K><K><A><E><P><A><T><G><K><N><L><G><A><V><K><G><R><Q><K><A><E><E><K><A><A><A><E><E><L><A><E><A><R><K><L><A><D><F><F><A><N><E><K><T><V><V><E><L><T><G><K><S><G><T><D><G><R><L><F><G><A><V><S><T><K><Q><I><A><A><A><L><E><K><Q...
Binds to the 23S rRNA.<BOP>
Q03UT5
Q3K559
ILVD_PSEPF
Dihydroxy-acid dehydratase
Pseudomonas
<M><P><D><Y><R><S><K><T><S><T><H><G><R><N><M><A><G><A><R><A><L><W><R><A><T><G><M><K><D><D><D><F><K><K><P><I><I><A><I><A><N><S><F><T><Q><F><V><P><G><H><V><H><L><K><D><L><G><Q><L><V><A><R><E><I><E><R><A><G><G><V><A><K><E><F><N><T><I><A><V><D><D><G><I><A><M><G><H><D><G><M><L><Y><S><L><P><S><R><E><I><I><A><D><S><V><E><Y><M...
Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (...
Q3K559
Q9RV69
HIUH_DEIRA
5-hydroxyisourate hydrolase
Deinococcus
<M><S><G><H><P><G><L><T><T><H><V><L><D><T><A><R><G><K><P><A><A><G><V><R><V><Q><L><C><R><V><T><G><D><T><R><T><P><V><T><E><A><V><T><N><S><D><G><R><T><D><A><P><L><I><E><R><G><S><L><K><Q><G><T><Y><E><L><T><F><H><V><A><D><Y><F><K><G><F><V><A><A><A><D><P><P><F><L><D><V><V><T><L><R><F><T><V><G><D><T><S><G><H><Y><H><V><P><L><V...
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).<BOP>
Q9RV69
Q0VME7
HFQ_ALCBS
RNA-binding protein Hfq
Alcanivorax
<M><S><K><G><H><S><L><Q><D><P><F><L><N><A><L><R><K><E><R><I><P><V><S><I><F><L><V><N><G><I><K><L><Q><G><Q><I><E><S><F><D><Q><Y><V><V><L><L><K><N><A><V><S><Q><M><V><Y><K><H><A><I><S><T><V><V><P><A><R><N><P><R><A><T><G><N><P><A><M><A><A><G><A><T><A><A><P><A><A><D><E><G><Y><G><N><Q>
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.<BOP>
Q0VME7
B1Y9B8
RS4_PYRNV
30S ribosomal protein S4
Pyrobaculum
<M><G><G><L><K><K><P><K><K><K><Y><L><A><G><K><P><K><K><I><W><N><K><Q><L><L><L><E><E><L><Q><L><M><G><E><Y><G><L><R><N><K><K><E><L><W><L><A><R><A><H><L><K><W><I><V><R><R><A><R><S><L><L><S><M><T><A><E><E><R><A><P><L><E><L><P><F><K><E><K><L><Y><K><M><G><F><I><E><D><P><N><V><P><L><D><R><V><L><S><L><D><V><R><A><I><L><E><R><R...
With S5 and S12 plays an important role in translational accuracy.<BOP>
B1Y9B8
B1LQL7
ULAE_ECOSM
L-xylulose-5-phosphate 3-epimerase
Escherichia
<M><L><S><K><Q><I><P><L><G><I><Y><E><K><A><L><P><A><G><E><C><W><L><E><R><L><Q><L><A><K><K><L><G><F><D><F><V><E><M><S><V><D><E><T><D><D><R><L><S><R><L><D><W><S><R><E><Q><R><L><A><L><V><N><A><I><V><E><T><G><V><R><V><P><S><M><C><L><S><A><H><R><R><F><P><L><G><S><E><D><D><A><V><R><A><Q><G><L><E><I><M><R><K><A><I><Q><F><A><Q...
Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization.<BOP>
B1LQL7
Q115S4
RL9_TRIEI
50S ribosomal protein L9
Trichodesmium
<M><A><K><K><L><Q><V><V><L><N><K><D><V><N><K><L><G><K><S><G><D><V><V><D><V><A><P><G><Y><A><R><N><Y><L><I><P><N><K><I><A><F><R><T><T><P><G><V><L><K><Q><V><E><R><R><Q><E><Q><E><R><Q><R><Q><I><E><L><K><Q><G><A><L><A><Q><K><T><A><L><E><T><V><G><R><F><K><I><A><K><Q><V><G><E><N><D><A><I><F><G><T><V><T><D><R><E><L><V><E><V><I...
Binds to the 23S rRNA.<BOP>
Q115S4
Q39EA4
MGSA_BURL3
Methylglyoxal synthase
Burkholderia cepacia complex
<M><S><K><P><R><I><A><L><I><A><H><D><A><K><K><D><E><I><V><A><L><A><G><E><F><R><A><T><L><A><Q><C><R><L><V><A><T><G><T><T><G><G><R><I><A><D><A><H><G><L><E><V><E><R><K><L><S><G><P><L><G><G><D><L><Q><I><G><A><E><L><A><D><G><R><I><D><I><V><V><F><L><R><D><P><M><T><A><Q><P><H><D><P><D><I><T><A><L><V><R><A><C><D><V><H><D><V><P...
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.<BOP>
Q39EA4
A6W3T0
ATPA2_MARMS
F-ATPase subunit alpha 2
Marinomonas
<M><Q><Q><L><N><P><S><E><I><S><E><I><I><K><K><R><I><E><N><L><D><V><S><S><D><A><Q><N><E><G><T><I><V><S><V><A><D><G><I><V><L><I><H><G><L><A><D><V><M><Y><G><E><M><I><E><F><P><G><G><V><Y><G><I><A><L><N><L><E><R><D><S><V><G><A><V><V><L><G><K><Y><Q><D><L><V><E><G><Q><K><V><K><C><T><G><R><I><L><E><V><P><I><G><P><E><L><L><G><R...
Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP>
A6W3T0
B2UYC5
RL6_CLOBA
50S ribosomal protein L6
Clostridium
<M><S><R><V><G><R><L><P><I><A><V><P><A><G><I><T><V><T><V><T><P><D><N><V><V><T><V><K><G><P><K><G><E><L><V><K><T><M><H><K><D><I><N><I><A><V><E><N><N><E><V><I><V><T><R><P><S><D><Q><K><A><H><R><A><L><H><G><L><T><R><A><L><I><N><N><M><V><I><G><V><N><E><G><Y><Q><K><T><L><E><L><V><G><V><G><Y><R><A><Q><L><Q><G><K><K><L><V><M><N...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
B2UYC5
A6VLK4
RL18_ACTSZ
50S ribosomal protein L18
Actinobacillus
<M><D><K><K><S><A><R><I><R><R><A><A><R><A><R><H><M><M><R><E><Q><G><V><T><R><L><V><V><H><R><T><P><R><H><I><Y><A><Q><V><I><A><P><N><G><S><E><V><L><A><A><A><S><T><V><E><K><E><I><S><A><Q><V><K><Y><T><G><N><K><D><A><A><A><V><V><G><K><L><V><A><E><R><A><L><A><K><G><V><K><D><V><A><F><D><R><S><G><F><K><Y><H><G><R><V><Q><S><L><A...
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP>
A6VLK4
Q3K9J0
UPPP2_PSEPF
Undecaprenyl pyrophosphate phosphatase 2
Pseudomonas
<M><D><L><L><T><L><F><K><V><L><I><L><G><A><V><E><G><L><T><E><F><L><P><I><S><S><T><G><H><Q><I><I><V><A><D><L><L><E><F><G><G><E><R><A><M><A><F><N><I><I><I><Q><L><G><A><I><L><A><V><V><W><E><F><R><P><K><I><F><E><I><V><K><G><L><P><T><Q><S><N><A><Q><R><F><T><R><N><L><L><I><A><F><F><P><A><V><I><L><G><V><L><F><A><D><T><I><H><E...
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP>
Q3K9J0
Q072L5
VM2_BOTAS
Disintegrin bothrasperin
Bothrops
<M><I><E><V><L><L><V><T><I><C><L><A><V><S><P><Y><Q><G><S><S><I><I><L><E><S><G><N><V><N><D><Y><E><V><V><Y><P><R><K><V><T><E><L><P><K><G><A><V><Q><P><K><Y><E><D><A><M><Q><Y><E><F><K><V><N><G><E><P><V><V><L><H><L><E><K><N><K><G><L><F><S><E><D><Y><S><E><T><H><Y><S><P><D><G><R><K><I><I><T><Y><P><S><F><E><D><H><C><Y><Y><H><G...
Disintegrin: Inhibits ADP- (IC(50)=59 nM) and collagen-induced (IC(50)=49 nM) aggregation of human platelets. In vitro, inhibits adhesion of endothelial cells to vitronectin, type-I collagen and, to a lower degree, fibronectin and laminin.<BOP>
Q072L5
Q97WG4
CAPPA_SACS2
Phosphoenolpyruvate carboxylase
Saccharolobus
<M><R><I><I><P><R><T><M><S><T><Q><H><P><D><N><A><K><V><P><E><W><A><K><S><E><V><I><E><G><E><D><E><V><K><E><A><F><L><A><Y><S><M><Y><G><V><H><E><V><M><W><D><A><E><G><K><D><V><D><T><H><V><V><R><K><L><L><S><N><Y><P><D><Y><F><R><E><H><I><L><G><K><D><L><F><L><T><Y><R><L><P><N><P><K><V><E><G><A><D><R><K><V><F><A><E><T><M><E><S...
Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.<BOP>
Q97WG4
Q6FCH8
OTC_ACIAD
Ornithine carbamoyltransferase
Acinetobacter
<M><A><L><R><H><F><L><T><L><R><D><L><S><S><L><E><L><N><S><I><L><D><R><A><S><E><L><K><R><Q><Q><H><A><N><Q><V><Y><Q><P><F><K><G><K><V><L><G><M><I><F><E><K><S><S><T><R><T><R><I><S><F><E><A><G><I><C><Q><F><G><G><S><A><I><F><L><S><P><R><D><T><Q><L><G><R><G><E><P><I><E><D><S><A><R><V><I><S><S><M><L><D><I><V><M><I><R><T><F><G...
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.<BOP>
Q6FCH8
Q8CIZ9
NOX1_MOUSE
NADPH oxidase 1
Mus
<M><A><G><E><L><R><G><S><R><G><P><L><Q><R><I><Q><I><A><P><R><E><A><P><N><L><H><L><T><M><G><N><W><L><V><N><H><W><L><S><V><L><F><L><V><S><W><L><G><L><N><I><F><L><F><V><Y><A><F><L><N><Y><E><K><S><D><K><Y><Y><Y><T><R><E><I><L><G><T><A><L><A><L><A><R><A><S><A><L><C><L><N><F><N><S><M><M><I><L><I><P><V><C><R><N><L><L><S><F><L...
Pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism.<BOP>
Q8CIZ9
A8YVT2
TRMD_LACH4
tRNA [GM37] methyltransferase
Lactobacillus
<M><K><I><N><V><L><T><L><F><P><D><M><F><T><P><L><Q><V><S><M><L><G><R><G><L><E><D><G><K><W><D><L><N><L><V><N><F><R><D><F><T><T><D><V><H><H><H><V><D><D><T><P><Y><G><G><G><A><G><M><V><L><Q><I><M><P><I><K><K><A><L><D><S><L><P><S><T><G><K><V><I><I><T><A><P><Q><G><K><T><F><N><E><Q><M><A><Q><D><W><A><K><E><D><E><L><T><F><I><C...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
A8YVT2
Q3SKJ3
SURE_THIDA
Nucleoside 5'-monophosphate phosphohydrolase
Thiobacillus
<M><R><I><L><L><S><N><D><D><G><Y><F><A><P><G><L><A><A><L><A><E><A><L><A><P><L><A><E><V><T><V><V><A><P><E><R><D><R><S><G><A><S><N><S><L><T><L><D><R><P><L><M><L><R><Q><A><P><S><G><F><Y><Y><V><N><G><T><P><T><D><C><V><H><L><A><V><T><G><M><L><D><H><L><P><D><M><V><I><S><G><I><N><H><G><A><N><M><G><D><D><T><I><Y><S><G><T><V><A...
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.<BOP>
Q3SKJ3
Q86UX2
ITIH5_HUMAN
Inter-alpha-trypsin inhibitor heavy chain H5
Homo
<M><L><L><L><L><G><L><C><L><G><L><S><L><C><V><G><S><Q><E><E><A><Q><S><W><G><H><S><S><E><Q><D><G><L><R><V><P><R><Q><V><R><L><L><Q><R><L><K><T><K><P><L><M><T><E><F><S><V><K><S><T><I><I><S><R><Y><A><F><T><T><V><S><C><R><M><L><N><R><A><S><E><D><Q><D><I><E><F><Q><M><Q><I><P><A><A><A><F><I><T><N><F><T><M><L><I><G><D><K><V><Y...
May act as a tumor suppressor.<BOP>
Q86UX2
Q12AT7
SSRP_POLSJ
Small protein B
unclassified Polaromonas
<M><R><I><A><D><N><K><K><A><I><F><N><Y><H><I><E><E><R><F><E><A><G><M><V><L><E><G><W><E><V><K><S><V><R><E><G><K><V><Q><L><T><D><G><Y><V><V><I><R><G><G><E><L><F><I><I><G><C><Q><I><N><P><L><G><T><A><S><T><H><V><R><P><D><S><V><R><T><K><K><L><L><M><H><K><D><E><I><R><R><L><V><G><K><V><E><Q><K><G><F><T><L><V><P><L><N><M><H><W...
Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemb...
Q12AT7