accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
Q5FUH9
RNH_GLUOX
Ribonuclease H
Gluconobacter
<M><S><E><A><S><G><E><R><P><R><V><E><I><W><T><D><G><G><C><K><P><N><P><G><P><G><G><W><G><A><L><L><V><C><R><G><Q><E><K><E><L><L><G><G><D><P><E><T><T><N><N><R><M><E><L><T><A><A><A><E><A><L><E><A><L><K><R><P><C><I><V><T><L><H><T><D><S><E><Y><L><R><N><G><I><T><R><W><H><T><G><W><V><R><R><K><W><R><N><A><A><G><D><P><V><A><N><M...
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP>
Q5FUH9
P15019
TAL1_YEAST
Transaldolase
Saccharomyces
<M><S><E><P><A><Q><K><K><Q><K><V><A><N><N><S><L><E><Q><L><K><A><S><G><T><V><V><V><A><D><T><G><D><F><G><S><I><A><K><F><Q><P><Q><D><S><T><T><N><P><S><L><I><L><A><A><A><K><Q><P><T><Y><A><K><L><I><D><V><A><V><E><Y><G><K><K><H><G><K><T><T><E><E><Q><V><E><N><A><V><D><R><L><L><V><E><F><G><K><E><I><L><K><I><V><P><G><R><V><S><T...
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP>
P15019
Q14G45
UNG_FRAT1
Uracil-DNA glycosylase
Francisella
<M><T><W><S><D><I><L><A><E><E><K><Q><K><P><Y><F><K><Q><I><L><D><F><L><A><C><E><S><A><K><G><K><V><I><F><P><T><K><E><N><I><F><N><A><F><K><Y><T><E><L><D><N><L><K><V><V><I><L><G><Q><D><P><Y><H><N><Y><N><Q><A><H><G><L><A><F><S><V><Q><K><G><V><D><I><P><P><S><L><Q><N><I><Y><K><E><L><A><R><S><I><P><E><F><K><T><P><N><H><G><Y><L...
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.<BOP>
Q14G45
P0C6R3
EST4A_BOVIN
Carboxylesterase 4A
Bos
<M><N><W><I><L><C><L><S><L><T><L><L><L><V><V><Q><T><A><W><G><A><L><H><T><K><E><P><L><A><D><T><K><Y><G><T><L><R><G><K><Q><I><H><V><G><K><T><P><I><N><V><F><L><G><V><P><F><S><K><P><P><V><G><A><H><R><F><A><A><P><E><P><P><E><P><W><E><G><I><R><D><A><T><T><Y><A><P><V><C><L><Q><E><S><W><G><Q><V><T><S><M><Y><F><N><T><H><K><R><Y...
Probable carboxylesterase.<BOP>
P0C6R3
Q8PNS4
RL3_XANAC
50S ribosomal protein L3
Xanthomonas
<M><T><K><K><Y><S><L><G><F><V><G><R><K><A><G><M><S><R><V><F><T><E><D><G><R><S><V><P><V><T><L><I><E><A><T><P><N><R><I><A><Q><I><K><T><V><E><V><D><G><Y><S><A><V><Q><V><T><V><G><A><R><R><A><A><L><V><N><K><P><A><A><G><H><F><A><K><A><K><V><E><A><G><R><G><L><W><E><F><R><V><E><D><A><Q><L><G><D><F><A><V><G><G><E><I><K><A><D><I...
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP>
Q8PNS4
Q2NV44
FOLD_SODGM
Methenyltetrahydrofolate cyclohydrolase
Sodalis
<M><V><A><K><I><I><D><G><R><A><V><A><Q><Q><V><R><S><E><V><A><A><R><I><Q><A><R><L><K><A><G><K><R><A><P><G><L><A><V><V><L><V><G><G><D><P><A><S><Q><I><Y><V><A><S><K><R><K><A><C><E><D><V><G><F><I><S><L><S><Y><D><L><P><N><T><V><T><E><A><A><L><L><A><L><I><D><Q><L><N><A><D><H><R><V><N><G><I><L><V><Q><L><P><L><P><A><G><I><D><N...
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP>
Q2NV44
A9BE89
PSAJ_PROM4
Photosystem I reaction center subunit IX
Prochlorococcus
<M><F><K><L><F><S><T><K><W><F><R><S><A><P><V><V><A><T><I><W><I><V><L><T><A><G><I><L><V><E><W><N><R><F><V><P><D><L><L><F><H><P><G><L>
May help in the organization of the PsaE and PsaF subunits.<BOP>
A9BE89
Q3YZ45
GUAA_SHISS
Glutamine amidotransferase
Shigella
<M><T><E><N><I><H><K><H><R><I><L><I><L><D><F><G><S><Q><Y><T><Q><L><V><A><R><R><V><R><E><L><G><V><Y><C><E><L><W><A><W><D><V><T><E><A><Q><I><R><D><F><N><P><S><G><I><I><L><S><G><G><P><E><S><T><T><E><E><N><S><P><R><A><P><Q><Y><V><F><E><A><G><V><P><V><F><G><V><C><Y><G><M><Q><T><M><A><M><Q><L><G><G><H><V><E><A><S><N><E><R><E...
Catalyzes the synthesis of GMP from XMP.<BOP>
Q3YZ45
Q1ACL6
PSBK_CHAVU
Photosystem II reaction center protein K
Chara
<M><I><L><Y><S><H><L><S><T><L><I><D><I><D><L><S><N><N><I><F><L><A><K><L><P><E><A><Y><A><I><F><D><P><L><V><D><V><M><P><V><I><P><V><F><F><L><L><L><A><F><V><W><Q><A><S><V><S><F><R>
One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, a...
Q1ACL6
Q3AKU3
KHSE_SYNSC
Homoserine kinase
unclassified Synechococcus
<M><A><Q><P><R><I><G><Q><K><V><V><V><D><V><P><A><T><T><A><N><L><G><P><G><F><D><C><L><G><A><A><L><D><L><N><N><R><F><A><M><R><R><I><E><G><G><G><E><R><F><E><L><I><I><E><G><S><E><G><S><H><L><R><G><G><P><E><N><L><V><Y><R><A><A><Q><R><V><W><K><A><A><G><L><E><P><V><A><L><E><A><R><V><R><L><A><V><P><P><A><R><G><L><G><S><S><A><T...
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.<BOP>
Q3AKU3
P95677
CH10_RHOCA
Chaperonin-10
Rhodobacter
<M><A><F><K><P><L><H><D><R><V><L><V><K><R><V><Q><S><E><E><K><T><K><G><G><L><I><I><P><D><T><A><K><E><K><P><A><E><G><E><V><V><A><V><G><A><G><A><R><K><D><S><G><E><L><I><A><P><A><V><A><V><G><D><R><I><L><F><G><K><W><S><G><T><E><V><T><L><D><G><V><E><M><L><I><M><K><E><S><D><I><M><G><I><I><S>
Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of ...
P95677
B2IQ29
OBG_STRPS
GTP-binding protein Obg
Streptococcus
<M><S><M><F><L><D><T><A><K><I><K><V><K><A><G><N><G><G><D><G><M><V><A><F><R><R><E><K><Y><V><P><N><G><G><P><W><G><G><D><G><G><R><G><G><N><V><V><F><V><V><D><E><G><L><R><T><L><M><D><F><R><Y><N><R><H><F><K><A><D><S><G><E><K><G><M><T><K><G><M><H><G><R><G><A><E><D><L><R><V><R><V><P><Q><G><T><T><V><R><D><A><E><T><G><K><V><L><T...
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B...
B2IQ29
P27093
INHBB_CHICK
Activin beta-B chain
Gallus
<M><D><G><A><A><R><R><G><V><L><A><A><L><L><A><C><G><L><L><L><L><G><A><A><A><T><P><T><P><P><P><A><G><S><S><P><Q><D><T><C><T><S><C><G><F><R><R><P><E><E><P><G><K><V><D><G><D><F><L><E><A><V><K><R><H><I><L><S><R><L><Q><M><R><D><R><P><N><I><T><H><A><V><P><K><A><A><M><V><T><A><L><R><K><L><H><A><G><K><V><R><E><D><G><R><V><E><I...
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid diffe...
P27093
Q9FLK2
CX5C3_ARATH
Cytochrome c oxidase polypeptide Vc-3
Arabidopsis
<M><A><G><H><K><I><A><H><A><T><L><K><G><P><S><V><V><K><E><L><V><I><G><L><T><L><G><L><A><A><G><G><L><W><K><M><H><H><W><N><E><Q><R><K><T><R><V><F><Y><D><L><L><E><R><G><E><I><G><V><V><V><T><E><E>
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.<BOP>
Q9FLK2
A1WE11
HFQ_VEREI
RNA-binding protein Hfq
Verminephrobacter
<M><S><N><K><G><Q><L><L><Q><E><P><F><L><N><T><L><R><R><E><H><V><P><V><S><I><Y><L><V><N><G><I><K><L><Q><G><Q><I><E><S><F><D><Q><Y><V><V><L><L><R><N><T><V><T><Q><M><V><F><K><H><A><I><S><T><I><V><P><G><R><A><V><H><F><S><T><A><E><P><A><D><A><N><S><N><N><G>
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.<BOP>
A1WE11
Q2SLV8
ECTC_HAHCH
N-acetyldiaminobutyrate dehydratase
Hahella
<M><I><V><R><T><L><E><Q><A><R><Q><S><D><R><R><V><K><A><D><N><W><E><S><V><R><M><L><L><K><D><D><N><M><G><F><S><F><H><I><T><T><L><Y><A><N><K><E><T><P><I><H><Y><Q><N><H><L><E><S><V><Y><C><I><S><G><E><G><E><V><E><T><V><A><D><G><E><V><H><A><I><K><P><G><T><L><Y><V><L><D><K><H><D><K><H><L><L><R><A><F><S><E><M><T><V><A><C><V><F...
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.<BOP>
Q2SLV8
Q2JRN5
PSBX2_SYNJA
Photosystem II reaction center X protein 2
unclassified Synechococcus
<M><T><P><S><L><A><N><F><L><W><S><L><V><Y><G><A><V><V><L><G><L><L><F><G><A><I><V><F><V><S><Q><R><D><R><V><R><R><R>
Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.<BOP>
Q2JRN5
Q5Y5T3
ZDH23_MOUSE
Zinc finger DHHC domain-containing protein 23
Mus
<M><K><P><V><K><K><K><K><T><E><E><P><E><L><E><P><L><C><C><C><E><Y><I><D><R><N><G><E><K><N><H><V><A><A><C><L><C><D><C><Q><D><L><D><E><G><C><D><R><W><L><T><C><Q><S><L><R><P><E><T><C><E><R><I><T><D><T><I><S><D><R><L><R><I><P><W><L><R><G><A><K><K><V><N><I><S><I><V><P><P><L><V><L><L><P><V><F><L><H><V><A><S><W><H><F><L><L><G...
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates and be involved in a variety of cellular processes. Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane. May be involved in NOS1 regulation and targeting t...
Q5Y5T3
Q1GE13
RUVB_RUEST
Holliday junction ATP-dependent DNA helicase RuvB
unclassified Ruegeria
<M><I><D><A><D><P><T><L><R><P><E><P><L><P><E><D><N><D><R><A><L><R><P><Q><G><L><G><E><F><I><G><Q><A><E><A><R><A><N><L><R><V><F><I><E><S><A><R><R><R><G><E><A><M><D><H><T><L><F><H><G><P><P><G><L><G><K><T><T><L><A><Q><I><V><A><R><E><L><G><V><N><F><R><M><T><S><G><P><V><L><A><K><A><G><D><L><A><A><I><L><T><N><L><E><A><R><D><V...
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.<BOP>
Q1GE13
P52074
GLCF_ECOLI
Glycolate oxidase subunit GlcF
Escherichia
<M><Q><T><Q><L><T><E><E><M><R><Q><N><A><R><A><L><E><A><D><S><I><L><R><A><C><V><H><C><G><F><C><T><A><T><C><P><T><Y><Q><L><L><G><D><E><L><D><G><P><R><G><R><I><Y><L><I><K><Q><V><L><E><G><N><E><V><T><L><K><T><Q><E><H><L><D><R><C><L><T><C><R><N><C><E><T><T><C><P><S><G><V><R><Y><H><N><L><L><D><I><G><R><D><I><V><E><Q><K><V><K...
Component of a complex that catalyzes the oxidation of glycolate to glyoxylate . Is required for E.coli to grow on glycolate as a sole source of carbon . Is also able to oxidize D-lactate ((R)-lactate) with a similar rate . Does not link directly to O(2), and 2,6-dichloroindophenol (DCIP) and phenazine methosulfate (PM...
P52074
Q8VZR2
ASD2_ARATH
Beta-D-xylosidase
Arabidopsis
<M><D><M><E><T><S><W><R><F><L><R><S><V><C><L><L><S><F><I><L><G><S><F><S><V><Y><Q><T><L><C><L><V><D><A><Q><E><D><A><I><V><T><L><Q><V><D><A><S><N><V><T><R><R><P><I><P><E><T><L><F><G><I><F><F><E><E><I><N><H><A><G><A><G><G><L><W><A><E><L><V><S><N><R><G><F><E><A><G><G><Q><I><I><P><S><N><I><W><P><W><S><I><I><G><D><E><S><S><I...
May be involved in the coordinated dissolution of the cell wall matrix during abscission and in the secondary cell wall formation in xylem vessels.<BOP>
Q8VZR2
A5K6I6
GUF1_PLAVS
Ribosomal back-translocase
Plasmodium (Plasmodium)
<M><I><H><A><W><A><I><K><R><A><L><C><I><F><I><L><I><N><C><V><L><K><L><E><R><S><L><K><V><T><W><K><S><K><R><G><F><H><T><P><V><D><G><A><N><G><C><E><R><E><W><K><R><R><G><V><F><F><S><I><R><R><G><S><N><R><K><A><A><R><L><R><K><A><F><R><G><V><G><T><G><G><R><P><L><F><R><G><G><K><F><I><P><L><F><L><L><R><D><C><Q><R><S><G><L><N><E...
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.<BOP>
A5K6I6
Q1JN46
GLMU_STRPC
Glucosamine-1-phosphate N-acetyltransferase
Streptococcus
<M><T><N><Y><A><I><I><L><A><A><G><K><G><T><R><M><T><S><D><L><P><K><V><L><H><K><V><S><G><L><T><M><L><E><H><V><F><R><S><V><K><A><I><S><P><E><K><A><V><T><V><I><G><H><K><S><E><K><V><R><A><V><L><A><D><Q><S><A><F><V><H><Q><T><E><Q><L><G><T><G><H><A><V><M><M><A><E><T><Q><L><E><G><L><E><G><H><T><L><V><I><A><G><D><T><P><L><I><T...
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted ...
Q1JN46
Q256J8
RECA_CHLFF
Recombinase A
Chlamydia
<M><N><V><P><D><R><K><K><A><L><E><A><A><I><A><Y><I><E><K><Q><F><G><S><G><S><I><M><S><L><G><K><H><S><A><T><H><E><I><S><T><I><K><T><G><A><L><S><L><D><L><A><L><G><I><G><G><V><P><K><G><R><I><V><E><I><F><G><P><E><S><S><G><K><T><T><L><A><T><H><I><V><A><N><A><Q><K><M><G><G><V><A><A><Y><I><D><A><E><H><A><L><D><P><G><Y><A><S><L...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
Q256J8
B1I6L2
RF1_DESAP
Peptide chain release factor 1
Candidatus Desulforudis
<M><F><A><K><L><D><H><L><E><A><K><Y><E><E><L><N><R><L><I><S><D><P><V><V><I><Q><D><Q><E><R><W><R><G><Y><V><K><S><H><A><E><I><G><E><V><V><A><V><Y><R><E><Y><K><R><V><A><A><E><M><D><D><A><R><Q><M><L><R><E><E><Q><D><A><E><L><R><E><L><A><E><S><E><V><E><V><L><R><E><R><S><D><E><L><R><R><R><L><R><V><L><L><L><P><K><D><P><N><D><E...
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.<BOP>
B1I6L2
O94377
ATPK_SCHPO
ATP synthase subunit f, mitochondrial
Schizosaccharomyces
<M><A><P><F><P><L><K><S><F><I><P><P><Q><V><A><N><P><T><A><L><N><A><F><P><S><S><A><R><M><G><R><I><V><D><F><Y><S><R><L><P><H><G><P><A><P><K><K><S><S><N><S><F><F><S><W><Y><Y><K><K><Y><L><G><K><N><A><S><G><A><P><L><L><H><L><V><G><A><V><L><V><F><S><Y><A><S><E><Y><Y><Y><H><I><R><H><H><E><E><H>
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous ca...
O94377
Q97HF0
SCPA_CLOAB
Segregation and condensation protein A
Clostridium
<M><T><L><N><I><N><I><D><N><F><Q><G><P><F><D><L><L><L><H><L><I><R><K><N><K><M><D><I><Y><D><I><K><I><F><D><I><T><N><Q><Y><I><Q><Y><L><N><E><M><K><E><M><D><L><E><I><T><S><E><F><I><V><M><A><A><T><L><I><E><I><K><S><K><Y><L><L><P><K><T><K><E><E><E><E><E><K><E><E><S><D><P><T><K><E><L><V><S><K><L><V><E><Y><K><K><F><K><L><A><A...
Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.<BOP>
Q97HF0
Q19706
EIF3G_CAEEL
Eukaryotic translation initiation factor 3 subunit 4
Caenorhabditis
<M><T><G><I><N><A><M><A><P><A><P><E><V><V><S><W><A><E><A><V><E><Q><D><N><A><P><H><I><Q><E><G><A><D><G><T><R><T><E><T><A><F><T><E><V><D><G><V><R><W><K><V><V><T><Q><F><K><V><I><N><K><R><V><P><K><V><V><A><D><R><K><K><W><V><K><F><G><S><C><K><G><E><P><A><G><P><Q><V><A><T><T><Y><V><A><E><E><V><D><M><Q><F><T><R><N><R><A><G><E...
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and...
Q19706
A8NWK4
DRE2_COPC7
Anamorsin homolog
Coprinopsis
<M><A><P><T><A><V><Y><T><Q><K><D><S><P><S><S><S><Q><P><S><S><K><G><P><A><L><A><I><G><S><L><E><T><A><Q><D><G><K><Y><Q><S><L><I><T><E><L><E><A><T><R><Q><V><D><K><L><L><L><D><R><L><V><D><G><A><T><T><L><E><P><S><K><Y><N><S><V><H><V><T><L><A><S><S><D><Y><Q><S><L><Q><E><S><T><L><R><S><L><L><T><Q><L><L><T><G><L><T><P><L><G><T...
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CF...
A8NWK4
Q833M8
ENGB_ENTFA
Probable GTP-binding protein EngB
Enterococcus
<M><N><V><H><N><A><E><I><V><I><S><A><V><S><P><K><Q><Y><P><E><S><Q><L><P><E><I><A><L><A><G><R><S><N><V><G><K><S><S><F><I><N><T><L><I><N><R><K><N><L><A><R><T><S><G><K><P><G><K><T><Q><T><L><N><F><Y><L><I><E><D><A><L><H><F><V><D><V><P><G><Y><G><Y><A><K><V><S><K><T><E><R><A><K><W><G><K><M><I><E><T><Y><I><T><Q><R><E><Q><L><R...
Necessary for normal cell division and for the maintenance of normal septation.<BOP>
Q833M8
Q44633
MNME_BUCAP
tRNA modification GTPase MnmE
Buchnera
<M><I><R><N><D><T><I><I><A><Q><V><T><C><P><G><K><S><A><V><G><I><L><R><V><S><G><I><H><A><N><Q><V><A><F><A><V><L><G><K><I><P><K><P><R><F><A><T><Y><S><K><F><F><D><E><S><K><K><V><L><D><E><G><I><S><L><W><F><P><A><P><F><S><L><T><G><E><D><V><L><E><L><Q><G><H><G><N><P><F><I><M><D><L><L><I><K><R><I><L><C><L><K><N><I><K><I><R><I...
Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP>
Q44633
O94565
OMH4_SCHPO
O-glycoside alpha-1,2-mannosyltransferase homolog 4
Schizosaccharomyces
<M><L><G><W><N><K><H><V><F><F><S><E><S><R><I><N><F><R><C><L><L><R><K><K><L><K><K><R><C><P><L><S><A><R><F><V><L><V><L><L><L><I><V><L><I><F><I><L><K><M><G><Y><K><Q><L><I><Y><K><L><N><H><P><P><L><R><R><I><D><E><R><N><D><P><L><F><S><N><G><C><K><N><V><H><L><E><A><Q><L><H><P><R><M><N><A><T><F><V><M><L><A><R><N><S><D><L><P><G...
Probable mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins. Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.<BOP>
O94565
C1DI45
RPOZ_AZOVD
Transcriptase subunit omega
Azotobacter
<M><A><R><V><T><V><E><D><C><L><E><N><V><D><N><R><F><E><L><V><M><L><A><S><K><R><A><R><Q><L><A><T><G><G><K><E><P><R><L><P><W><E><N><D><K><P><T><V><V><A><L><R><E><I><A><A><G><L><V><D><Y><N><V><I><A><Q><D><E><I><V><A><E><E><P><L><F><A><A><F><E><E><D><S><N><E><A><L>
Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP>
C1DI45
A1S1K6
HEM6_SHEAM
Oxygen-dependent coproporphyrinogen-III oxidase
Shewanella
<M><G><L><P><N><A><E><E><V><K><A><F><L><M><Q><L><Q><A><N><I><C><A><G><L><E><R><L><D><G><Q><A><S><F><A><T><D><S><W><Q><R><A><E><G><G><G><G><I><S><R><V><L><T><D><G><A><V><F><E><Q><A><G><V><N><F><S><H><V><M><G><A><S><M><P><A><S><A><T><A><H><R><P><E><L><A><G><R><S><F><E><A><M><G><V><S><L><V><I><H><P><K><N><P><Y><I><P><T><T...
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.<BOP>
A1S1K6
A0A3B3IU63
H2AL3_HUMAN
Histone H2A-like 3
Homo
<M><A><G><N><K><M><F><C><R><P><R><R><Q><R><L><S><H><S><R><R><A><E><L><Q><F><P><V><S><H><L><E><R><C><L><R><E><S><Q><H><A><R><H><L><S><S><T><T><P><V><F><L><A><G><V><L><E><Y><L><T><A><N><I><L><E><K><V><G><K><E><V><K><N><S><C><R><L><C><I><T><P><E><H><V><K><R><A><L><Q><K><D><E><Q><L><R><W><I><L><E><L><E><D><D><T><H><S><Q><V...
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated v...
A0A3B3IU63
Q2RJM5
IF2_MOOTA
Translation initiation factor IF-2
Moorella
<M><A><K><T><R><V><Y><E><L><A><K><E><L><K><V><T><N><K><D><L><I><D><T><M><A><R><L><G><I><Y><T><R><S><H><M><S><V><L><E><N><G><E><V><I><K><V><R><N><H><Y><R><Q><Q><W><R><A><A><K><L><A><R><M><H><R><E><Q><A><T><L><K><G><E><G><P><V><P><T><R><G><V><P><D><A><P><R><A><E><E><V><P><S><R><Q><V><P><A><P><E><T><G><A><P><A><Q><A><T><G...
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.<BOP>
Q2RJM5
Q6ENI0
ATPI_ORYNI
F-ATPase subunit IV
Oryza
<M><N><I><I><P><C><S><I><K><T><L><K><G><L><Y><D><I><S><G><V><E><V><G><Q><H><F><Y><W><Q><I><G><G><F><Q><I><H><A><Q><V><L><I><T><S><W><V><V><I><T><I><L><L><G><S><V><I><I><A><V><R><N><P><Q><T><I><P><T><D><G><Q><N><F><F><E><Y><V><L><E><F><I><R><D><L><S><K><T><Q><I><G><E><E><Y><G><P><W><V><P><F><I><G><T><M><F><L><F><I><F><V...
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.<BOP>
Q6ENI0
Q65W40
RPOC_MANSM
Transcriptase subunit beta'
Basfia
<M><K><D><L><V><K><F><L><K><A><Q><S><K><T><S><E><D><F><D><V><I><K><I><G><L><A><S><P><D><M><I><R><S><W><S><F><G><E><V><K><K><P><E><T><I><N><Y><R><T><F><K><P><E><R><D><G><L><F><C><A><R><I><F><G><P><V><K><D><Y><E><C><L><C><G><K><Y><K><R><L><K><H><R><G><V><I><C><E><K><C><G><V><E><V><T><Q><T><K><V><R><R><E><R><M><G><H><I><E...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
Q65W40
A7RF00
MTNA_NEMVE
Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein
Nematostella
<M><S><L><E><A><I><K><Y><K><K><G><R><L><E><I><L><N><Q><L><L><L><P><H><E><S><T><Y><E><V><V><S><D><T><E><D><G><W><K><A><I><R><E><M><K><V><R><G><A><P><A><I><A><I><V><G><A><L><S><L><A><A><E><I><Y><S><K><P><F><A><S><S><E><E><L><A><E><F><V><K><Q><K><L><Q><Y><L><N><T><A><R><P><T><A><V><N><M><T><N><A><V><I><E><L><T><A><F><V><A...
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).<BOP>
A7RF00
B2JLS3
PHNW_PARP8
AEP transaminase
Paraburkholderia
<M><I><P><G><N><D><P><I><L><L><T><P><G><P><L><T><T><S><P><A><T><R><H><A><M><L><R><D><W><G><S><W><D><A><A><F><N><R><M><T><Q><S><V><C><T><D><L><I><E><I><V><H><G><E><N><E><Y><V><C><V><P><L><Q><G><S><G><T><F><A><V><E><A><A><L><G><T><L><V><P><R><D><G><R><V><L><V><P><N><N><G><A><Y><C><A><R><I><V><K><V><L><Q><R><L><G><I><A><H...
Involved in phosphonate degradation.<BOP>
B2JLS3
P41636
4CL_PINTA
4-coumaroyl-CoA synthase
Pinus subgen. Pinus
<M><A><N><G><I><K><K><V><E><H><L><Y><R><S><K><L><P><D><I><E><I><S><D><H><L><P><L><H><S><Y><C><F><E><R><V><A><E><F><A><D><R><P><C><L><I><D><G><A><T><D><R><T><Y><C><F><S><E><V><E><L><I><S><R><K><V><A><A><G><L><A><K><L><G><L><Q><Q><G><Q><V><V><M><L><L><L><P><N><C><I><E><F><A><F><V><F><M><G><A><S><V><R><G><A><I><V><T><T><A...
Carboxylate--CoA ligase that may use 4-coumarate as substrate. Follows a two-step reaction mechanism, wherein the carboxylate substrate first undergoes adenylation by ATP, followed by a thioesterification in the presence of CoA to yield the final CoA thioester.<BOP>
P41636
O75074
LRP3_HUMAN
105 kDa low-density lipoprotein receptor-related protein
Homo
<M><E><K><R><A><A><A><G><L><E><G><A><P><G><A><R><A><Q><L><A><V><V><C><L><V><N><I><F><L><T><G><R><L><S><S><A><V><P><A><L><A><A><C><S><G><K><L><E><Q><H><T><E><R><R><G><V><I><Y><S><P><A><W><P><L><N><Y><P><P><G><T><N><C><S><W><Y><I><Q><G><D><R><G><D><M><I><T><I><S><F><R><N><F><D><V><E><E><S><H><Q><C><S><L><D><W><L><L><L><G...
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.<BOP>
O75074
Q2SS11
METK_MYCCT
Methionine adenosyltransferase
Mycoplasma
<M><N><Q><N><I><E><K><R><L><F><T><S><E><S><V><S><E><G><H><P><D><K><I><C><D><Q><I><S><D><A><I><L><D><E><V><L><K><Q><D><K><N><A><K><V><A><C><E><V><F><T><T><T><N><Y><L><L><I><G><G><Q><I><S><S><T><A><I><V><D><Y><E><Q><V><A><R><D><V><L><K><K><I><G><Y><V><D><D><A><Y><G><I><N><A><N><T><C><K><I><D><I><K><I><E><S><Q><S><P><D><I...
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.<BOP>
Q2SS11
Q8FYT2
ISPG_BRUSU
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase
Brucella
<M><S><S><E><T><V><S><Y><F><S><H><P><F><P><R><R><Q><S><V><G><V><S><V><G><G><V><I><V><G><G><S><A><P><V><V><V><Q><S><M><T><N><T><D><T><A><D><V><D><S><T><V><A><Q><V><A><A><L><H><R><A><G><S><E><I><V><R><I><T><V><D><R><D><E><S><A><A><A><V><P><K><I><R><E><R><L><E><R><L><G><H><D><V><P><L><V><G><D><F><H><Y><I><G><H><K><L><L><A...
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.<BOP>
Q8FYT2
Q44452
TRAM_AGRFC
Transcriptional repressor TraM
Agrobacterium tumefaciens complex
<M><E><S><E><D><A><T><L><T><K><K><V><E><L><R><P><L><V><G><L><T><R><G><L><H><P><A><D><L><E><K><L><T><I><D><A><I><R><A><H><R><R><L><V><E><K><A><D><E><L><F><Q><A><L><P><E><S><Y><K><S><G><K><E><V><G><G><P><Q><H><L><C><Y><I><E><A><S><I><E><M><H><A><Q><M><S><A><V><S><T><L><I><S><I><L><G><Y><I><P><N><A><T><V><N>
Negatively regulates conjugation and the expression of tra genes by antagonizing TraR/AAI-dependent activation. TraM may either bind or modify TraR or AAI making them unavailable. Alternatively, TraM may bind tra promoters preventing TraR activation.<BOP>
Q44452
Q8STF0
CALM_STRIE
Calmodulin
Strongylocentrotus
<M><S><Q><E><L><T><I><N><A><D><Q><L><T><E><E><Q><I><A><E><F><K><E><A><F><S><L><F><D><K><D><G><D><G><T><I><T><T><K><E><L><G><T><V><M><R><S><L><G><Q><N><P><T><E><A><E><L><Q><D><M><I><N><E><V><D><A><D><G><N><G><T><I><D><F><P><E><F><L><T><M><M><A><R><K><M><K><D><T><D><S><E><E><E><I><R><E><A><F><R><V><F><D><K><D><G><N><G><F...
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.<BOP>
Q8STF0
Q5HA74
RNC_EHRRW
Ribonuclease III
Ehrlichia
<M><I><T><N><A><I><S><K><I><I><K><Y><D><F><K><N><T><Q><L><L><N><E><A><L><T><H><P><S><V><L><S><K><D><N><N><N><F><N><Y><E><R><L><E><F><L><G><D><A><V><L><N><L><V><I><S><E><M><L><F><N><I><F><P><Y><D><T><E><G><N><L><A><K><K><K><T><A><L><V><C><G><T><K><L><V><E><I><A><Q><S><I><N><L><G><I><F><I><I><M><S><D><G><E><R><S><C><G><G...
Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.<B...
Q5HA74
A1CAL7
SHO1_ASPCL
Osmosensor sho1
Aspergillus subgen. Fumigati
<M><A><R><F><R><A><S><N><I><L><G><D><P><F><A><L><A><T><I><S><I><A><I><L><A><W><I><I><A><F><I><S><S><I><I><A><N><I><K><M><A><D><Y><P><N><H><A><W><W><A><I><A><Y><M><F><C><C><T><I><G><V><T><V><V><V><G><S><D><T><G><L><V><Y><G><V><A><V><V><G><Y><L><S><A><G><L><V><L><T><S><L><S><V><N><T><L><V><Y><K><G><N><S><S><A><Q><A><A><A...
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.<BOP>
A1CAL7
P28422
RBL_HELNU
Ribulose bisphosphate carboxylase large chain
Heliamphora
<V><G><F><K><A><G><V><K><D><Y><K><L><T><Y><Y><T><P><D><Y><Q><T><K><A><T><D><I><L><A><A><F><R><V><T><P><Q><P><G><V><P><P><E><E><A><G><A><A><V><A><A><E><S><S><T><G><T><W><T><T><V><W><T><D><G><L><T><S><L><D><R><Y><K><G><R><C><Y><H><I><E><P><V><A><G><E><E><N><Q><Y><I><A><Y><V><A><Y><P><L><D><L><F><E><E><G><S><V><T><N><M><F...
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.<BOP>
P28422
B2J5P1
DXS_NOSP7
1-deoxyxylulose-5-phosphate synthase
Nostoc
<M><H><L><S><E><I><T><H><P><N><Q><L><H><G><L><S><V><R><Q><L><Q><Q><I><A><R><Q><I><R><D><K><H><L><Q><T><V><A><V><N><G><G><H><L><G><P><G><L><G><V><V><E><L><T><L><G><L><Y><Q><T><L><D><L><D><R><D><K><V><I><W><D><V><G><H><Q><A><Y><P><H><K><L><L><T><G><R><Y><D><R><F><H><T><L><R><Q><K><D><G><V><A><G><Y><L><K><L><C><E><N><K><F...
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).<BOP>
B2J5P1
Q2FY06
ERA_STAA8
GTPase Era
Staphylococcus
<M><T><E><H><K><S><G><F><V><S><I><I><G><R><P><N><V><G><K><S><T><F><V><N><R><V><I><G><H><K><I><A><I><M><S><D><K><A><Q><T><T><R><N><K><I><Q><G><V><M><T><R><D><D><A><Q><I><I><F><I><D><T><P><G><I><H><K><P><K><H><K><L><G><D><Y><M><M><K><V><A><K><N><T><L><S><E><I><D><A><I><M><F><M><V><N><A><N><E><E><I><G><R><G><D><E><Y><I><I...
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.<BOP>
Q2FY06
Q6YRC6
OBG_ONYPE
GTP-binding protein Obg
Candidatus Phytoplasma asteris
<M><F><S><L><H><F><V><D><E><A><F><N><E><V><F><A><G><N><G><G><H><G><I><V><A><F><R><R><E><K><Y><V><A><F><G><G><P><A><G><G><N><G><G><K><G><G><S><V><I><F><V><G><D><K><D><E><T><T><L><L><K><L><K><Y><Q><K><H><L><K><A><P><H><G><I><N><G><K><N><K><G><Q><N><G><A><N><A><P><H><L><Y><V><K><V><P><L><G><T><V><F><Y><T><A><D><N><K><F><L...
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B...
Q6YRC6
C5B7S4
ACCA_EDWI9
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Edwardsiella
<M><S><L><N><F><L><D><F><E><Q><P><I><A><E><L><E><A><K><I><D><S><L><N><A><L><S><R><Q><D><E><K><L><D><I><N><I><D><E><E><V><Q><R><L><R><E><K><S><V><E><L><T><R><K><I><F><A><D><L><G><A><W><Q><I><A><Q><L><A><R><H><P><R><R><P><Y><T><L><D><Y><I><Q><H><I><F><T><D><F><D><E><L><A><G><D><R><A><Y><A><D><D><K><A><I><V><G><G><M><A><R...
Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.<BOP>
C5B7S4
O67495
FLIN_AQUAE
Flagellar motor switch protein FliN
Aquifex
<M><E><E><Q><T><K><E><I><Q><E><E><K><K><E><T><P><Q><E><E><V><R><E><E><K><K><E><E><K><K><V><S><V><I><E><L><I><Q><H><F><S><D><I><P><V><E><V><E><V><V><V><G><R><A><N><K><T><L><G><E><L><L><A><M><G><I><G><S><V><I><E><I><D><R><E><P><K><D><L><V><D><I><K><V><N><G><K><L><I><A><K><G><E><L><V><I><I><D><G><K><I><G><V><K><I><K><E><V...
FliM is one of 2 proteins (FliG, FliN) that might form a switch complex that is proposed to be located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (Potential).<BOP>
O67495
C4L8Y5
DNAK_TOLAT
Heat shock protein 70
Tolumonas
<M><G><R><I><I><G><I><D><L><G><T><T><N><S><C><V><A><I><L><D><G><D><T><A><R><V><I><E><N><A><E><G><D><R><T><T><P><S><I><I><A><Y><T><D><D><G><E><I><L><V><G><Q><P><A><K><R><Q><S><I><T><N><P><K><N><T><L><Y><A><I><K><R><L><I><G><R><R><Y><E><D><E><E><V><Q><R><D><I><K><I><M><P><F><D><I><V><R><A><D><N><G><D><A><W><V><D><V><K><G...
Acts as a chaperone.<BOP>
C4L8Y5
Q91ZK0
AP2D_MOUSE
Activating enhancer-binding protein 2-delta
Mus
<M><S><T><T><F><P><G><L><V><H><D><A><E><I><R><H><D><G><S><N><S><Y><R><L><M><Q><L><G><C><L><E><S><V><A><N><S><T><V><A><Y><S><S><S><S><P><L><T><Y><S><T><T><G><T><E><F><A><S><P><Y><F><S><T><N><H><Q><Y><T><P><L><H><H><Q><S><F><H><Y><E><F><Q><H><S><H><P><A><V><T><P><D><A><Y><S><L><N><S><L><H><H><S><Q><Q><Y><Y><Q><Q><I><H><H...
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, ...
Q91ZK0
Q8Y1P9
CH10_RALSO
Chaperonin-10
Ralstonia
<M><N><L><R><P><L><H><D><R><V><I><V><K><R><L><D><N><E><T><K><T><A><S><G><I><V><I><P><D><A><A><A><E><K><P><D><Q><G><E><V><L><A><I><G><P><G><K><K><D><D><K><G><N><P><I><A><L><D><V><K><V><G><D><R><V><L><F><G><K><Y><A><G><Q><A><V><K><V><D><G><Q><E><L><L><V><M><R><E><E><D><I><M><A><V><V><T><K>
Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of ...
Q8Y1P9
A1TSN1
KTHY_ACIAC
dTMP kinase
Acidovorax
<M><Q><R><R><G><W><F><I><T><F><E><G><I><D><G><A><G><K><S><S><H><I><E><A><V><A><E><A><L><R><R><E><G><R><T><V><T><V><T><R><E><P><G><G><T><P><L><A><E><T><L><R><S><L><L><L><N><E><A><M><D><A><L><T><E><S><L><V><V><F><A><G><R><R><D><H><L><R><S><V><I><A><P><A><L><V><R><G><E><V><V><L><C><D><R><F><T><D><A><T><F><A><Y><Q><G><A><G...
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.<BOP>
A1TSN1
A1RFB7
YACG_SHESW
DNA gyrase inhibitor YacG
Shewanella
<M><P><L><T><V><K><C><P><I><C><K><T><P><V><E><W><A><P><Q><S><E><F><K><P><F><C><S><E><R><C><K><L><I><D><L><A><D><W><A><S><E><K><H><A><I><P><V><K><S><E><F><D><L><D><A><L><D><E><F><D><L><D><E><D><A><F><F><K><E>
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.<BOP>
A1RFB7
Q9R0U1
IP6K2_RAT
P(i)-uptake stimulator
Rattus
<M><S><P><A><F><R><T><M><D><V><E><P><R><T><K><G><I><L><L><E><P><F><V><H><Q><V><G><G><H><S><C><V><L><R><F><N><E><T><T><L><C><K><P><L><V><P><R><E><H><Q><F><Y><E><T><L><P><A><E><M><R><R><F><T><P><Q><Y><K><G><V><V><S><V><R><F><E><E><D><E><D><R><N><L><C><L><I><A><Y><P><L><K><G><D><H><G><P><V><D><I><V><D><N><S><D><C><E><P><K...
Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5).<BOP>
Q9R0U1
G5EI08
BAS2_MAGO7
Biotrophy-associated secreted protein 2
Pyricularia
<M><V><R><V><S><T><F><A><A><I><L><A><M><A><L><S><V><T><A><N><V><T><P><N><D><A><G><A><K><N><V><G><T><G><N><G><Q><Q><F><I><T><G><G><C><V><N><G><T><D><C><Q><S><R><C><C><A><G><N><G><E><N><K><G><V><C><S><N><E><V><A><A><N><Q><N><G><K><T><G><C><G><F><E><D><P><N><K><A><Q><T><V><K><E><A><K><E><Q><V><K><K><Q><G><F>
Secreted effector involved in biotrophic colonization of plant cells.<BOP>
G5EI08
P40334
PEPX_LACDL
X-prolyl-dipeptidyl aminopeptidase
Lactobacillus
<M><K><Y><N><Q><Y><A><Y><V><E><T><S><P><E><K><A><T><E><E><L><L><A><I><N><F><L><P><E><N><Y><S><S><L><S><F><S><E><L><L><A><V><L><T><G><N><V><L><A><E><A><T><T><R><Q><A><K><D><A><K><L><A><E><F><A><V><D><D><Q><T><D><L><A><A><F><L><L><D><T><P><T><A><I><T><A><S><Q><F><A><N><V><A><L><Q><L><L><G><Y><H><P><N><Y><D><Y><S><L><T><D...
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.<BOP>
P40334
A6X191
GATB_BRUA4
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
Brucella
<M><S><L><I><D><T><R><I><P><E><P><K><R><F><I><S><G><A><T><G><D><W><E><V><V><I><G><M><E><V><H><A><Q><V><T><S><E><S><K><L><F><S><G><A><S><T><S><F><G><A><E><P><N><S><N><V><S><L><V><D><A><A><M><P><G><M><L><P><V><I><N><L><E><C><V><K><Q><A><V><R><T><G><I><G><L><N><A><Q><I><N><L><K><S><V><F><D><R><K><N><Y><F><Y><P><D><L><P><Q...
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ...
A6X191
C1C5E4
MUTS2_STRP7
Endonuclease MutS2
Streptococcus
<M><N><K><K><I><L><E><T><L><E><F><D><K><I><K><A><L><F><E><P><H><L><L><T><E><Q><G><L><E><Q><L><R><Q><L><A><P><T><A><K><A><D><K><I><K><Q><A><F><A><E><M><K><E><M><Q><A><L><F><V><E><Q><P><H><F><T><I><L><S><T><K><E><I><A><G><V><C><K><R><L><E><M><G><A><D><L><N><I><E><E><F><L><L><L><K><R><V><L><L><T><S><R><E><L><Q><S><F><Y><A...
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.<BOP>
C1C5E4
Q31QY2
FBSB_SYNE7
Fructose-1,6-bisphosphatase F-I
Synechococcus
<M><E><K><T><I><G><L><E><I><I><E><V><V><E><Q><A><A><I><A><S><A><R><L><M><G><K><G><E><K><N><E><A><D><R><V><A><V><E><A><M><R><V><R><M><N><Q><V><E><M><L><G><R><I><V><I><G><E><G><E><R><D><E><A><P><M><L><Y><I><G><E><E><V><G><I><Y><R><D><A><D><K><R><A><G><V><P><A><G><K><L><V><E><I><D><I><A><V><D><P><C><E><G><T><N><L><C><A><Y...
Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively.<BOP>
Q31QY2
A0A0C3FBR2
TERS_PILCF
Terpene cyclase PILCRDRAFT_825684
Piloderma
<M><P><S><Q><S><L><T><I><R><L><P><K><F><E><E><T><F><S><V><F><P><D><N><G><L><N><P><H><Y><A><N><S><R><A><E><S><R><A><W><I><N><Q><Y><H><H><A><V><C><G><P><N><M><R><T><F><M><D><K><C><N><F><E><L><A><G><A><L><F><Y><P><Y><A><N><E><A><G><L><R><A><T><M><D><L><V><N><L><L><W><L><Y><D><E><L><T><D><T><K><T><E><T><E><A><V><N><A><A><H...
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to various sesquiterpenes, including beta-elemene, viridiflorene and gamma-cadinene . Gamma-cadinene is the major product of PILCRDRAFT_825684 .<BOP>
A0A0C3FBR2
Q7T229
VSPH_BOTJR
Serine proteinase-like protein
Bothrops
<M><V><L><I><R><V><L><A><N><L><L><I><L><Q><L><S><Y><A><Q><K><A><S><E><L><I><I><G><G><D><E><C><N><I><N><E><H><R><F><L><V><A><L><Y><T><S><R><S><R><R><F><H><C><S><G><T><L><I><N><Q><E><W><V><L><T><A><A><N><C><D><R><K><N><I><R><I><K><L><G><M><H><S><K><N><V><T><N><E><D><E><Q><T><R><V><P><K><E><K><F><F><C><L><S><S><K><T><Y><T...
Snake venom serine protease homolog that may act in the hemostasis system of the prey.<BOP>
Q7T229
A3CNJ9
UVRB_STRSV
Excinuclease ABC subunit B
Streptococcus
<M><I><N><R><I><T><D><N><K><F><E><L><V><S><K><Y><K><P><S><G><D><Q><P><Q><A><I><E><Q><L><V><D><N><I><E><G><G><E><K><A><Q><I><L><M><G><A><T><G><T><G><K><T><Y><T><M><S><Q><V><I><A><Q><V><N><K><P><T><L><V><I><A><H><N><K><T><L><A><G><Q><L><Y><G><E><F><K><E><F><F><P><N><N><A><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi...
A3CNJ9
Q8DSE9
NUSB_STRMU
Antitermination factor NusB
Streptococcus
<M><T><N><V><F><V><D><S><R><R><D><L><R><E><R><A><F><Q><A><L><F><S><L><E><F><G><G><D><N><L><T><A><A><R><F><A><Y><T><Y><D><K><N><E><E><E><E><A><E><L><P><L><F><L><L><T><L><I><Q><G><V><S><D><C><R><R><E><I><D><K><N><I><S><I><H><L><K><S><G><W><T><L><S><R><L><T><L><I><D><K><S><L><L><R><L><G><L><Y><E><I><K><Y><H><K><E><T><P><E...
Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.<BOP>
Q8DSE9
B9DNG3
APT_STACT
Adenine phosphoribosyltransferase
Staphylococcus
<M><D><L><K><Q><Y><V><S><E><V><Q><D><W><P><K><E><G><V><D><F><K><D><I><T><T><I><M><D><N><G><E><A><Y><G><Y><A><T><D><Q><I><V><E><F><A><R><E><K><E><V><D><I><V><V><G><P><E><A><R><G><F><I><I><G><C><P><V><A><Y><S><M><G><I><G><F><A><P><V><R><K><E><G><K><L><P><R><E><V><I><R><Y><E><Y><D><L><E><Y><G><T><N><V><L><T><M><H><K><D><A...
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.<BOP>
B9DNG3
A6UPD8
RF1_METVS
Translation termination factor aRF1
Methanococcus
<M><S><E><N><S><S><T><D><M><Y><L><F><K><K><S><L><K><E><L><K><G><K><R><G><K><G><T><E><L><I><S><V><Y><V><P><A><G><R><R><L><S><D><I><S><Q><H><L><R><Q><E><L><S><Q><S><S><N><I><K><S><K><T><T><M><K><N><V><Q><S><A><I><E><V><I><L><Q><R><L><K><L><L><K><E><P><L><E><K><G><V><I><I><F><A><G><M><I><P><R><G><G><P><G><T><E><K><M><E><V...
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.<BOP>
A6UPD8
B9KML7
FMT_CERSK
Methionyl-tRNA formyltransferase
Cereibacter
<M><R><L><I><F><M><G><S><P><D><F><S><V><P><V><L><E><A><L><H><A><H><H><E><V><V><C><V><Y><C><Q><P><P><R><P><A><G><R><G><K><K><D><R><P><T><P><V><Q><T><R><A><E><E><L><G><L><P><V><R><H><P><T><S><L><R><T><P><E><A><Q><A><E><F><A><A><L><G><A><E><A><A><V><V><V><A><Y><G><L><I><L><P><Q><P><I><L><D><A><P><E><R><G><C><L><N><I><H><A...
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.<BOP>
B9KML7
A6NFY7
SDHF1_HUMAN
LYR motif-containing protein 8
Homo
<M><S><R><H><S><R><L><Q><R><Q><V><L><S><L><Y><R><D><L><L><R><A><G><R><G><K><P><G><A><E><A><R><V><R><A><E><F><R><Q><H><A><G><L><P><R><S><D><V><L><R><I><E><Y><L><Y><R><R><G><R><R><Q><L><Q><L><L><R><S><G><H><A><T><A><M><G><A><F><V><R><P><R><A><P><T><G><E><P><G><G><V><G><C><Q><P><D><D><G><D><S><P><R><N><P><H><D><S><T><G><A...
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduct...
A6NFY7
A4JBC1
RPPH_BURVG
(Di)nucleoside polyphosphate hydrolase
Burkholderia cepacia complex
<M><L><D><R><E><G><F><R><P><N><V><G><I><I><L><L><N><A><R><N><E><V><F><W><G><K><R><L><R><E><H><S><W><Q><F><P><Q><G><G><I><K><Y><G><E><T><P><M><Q><A><M><Y><R><E><L><H><E><E><T><G><L><H><P><E><H><V><K><I><I><G><R><T><R><D><W><L><R><Y><E><V><P><D><K><F><I><K><R><E><V><R><G><H><Y><R><G><Q><K><Q><I><W><F><L><L><R><M><V><G><R...
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.<BOP>
A4JBC1
O13872
VPS28_SCHPO
ESCRT-I complex subunit vps28
Schizosaccharomyces
<M><T><E><Y><Y><D><L><N><L><L><E><K><E><T><S><E><E><N><N><F><H><T><K><N><Q><Q><V><R><E><D><L><S><I><L><Y><S><I><L><V><A><L><E><Q><L><E><K><A><F><T><K><D><A><V><S><T><S><D><F><N><S><T><C><E><L><L><I><Q><Q><W><E><S><C><F><S><D><E><R><V><T><Q><A><F><G><S><F><E><D><F><C><S><K><Y><R><L><Q><C><P><R><A><I><K><R><I><Q><E><G><I...
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.<BOP>
O13872
A2SE21
MSCL_METPP
Large-conductance mechanosensitive channel
Methylibium
<M><S><F><F><S><E><F><K><E><F><A><V><K><G><N><V><I><D><L><A><V><G><V><I><I><G><G><A><F><G><K><I><V><D><S><I><V><G><D><L><I><M><P><I><V><S><K><L><F><G><G><L><D><F><S><N><Y><Y><V><G><L><A><G><Q><A><A><G><L><P><L><A><E><A><K><K><A><G><A><V><F><A><Y><G><N><F><I><T><V><A><L><N><F><A><I><L><A><F><I><I><F><L><M><I><K><Q><I><N...
Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.<BOP>
A2SE21
A0Q8A2
CCA_FRATN
tRNA-NT
Francisella
<M><K><F><Y><L><V><G><G><A><V><R><D><M><L><L><G><I><T><P><K><D><K><D><W><V><V><V><G><A><T><E><D><E><M><L><A><N><G><F><I><K><I><A><A><N><F><P><V><F><I><H><P><Q><T><K><Q><E><Y><A><L><A><R><S><E><K><K><T><A><N><G><Y><H><G><F><E><V><N><F><S><K><Y><I><T><L><E><D><D><L><K><R><R><D><L><T><I><N><S><I><A><I><D><Q><N><N><K><V><I...
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.<BOP>
A0Q8A2
Q3T0S6
RL8_BOVIN
60S ribosomal protein L8
Bos
<M><G><R><V><I><R><G><Q><R><K><G><A><G><S><V><F><R><A><H><V><K><H><R><K><G><A><A><R><L><R><A><V><D><F><A><E><R><H><G><Y><I><K><G><I><V><K><D><I><I><H><D><P><G><R><G><A><P><L><A><K><V><V><F><R><D><P><Y><R><F><K><K><R><T><E><L><F><I><A><A><E><G><I><H><T><G><Q><F><V><Y><C><G><K><K><A><Q><L><N><I><G><N><V><L><P><V><G><T><M...
Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.<BOP>
Q3T0S6
Q7X9V2
PIE1_ARATH
Protein CHROMATIN REMODELING 13
Arabidopsis
<M><A><S><K><G><G><K><S><K><P><D><I><V><M><A><S><K><S><G><K><S><K><P><D><N><E><S><R><A><K><R><Q><K><T><L><E><A><P><K><E><P><R><R><P><K><T><H><W><D><H><V><L><E><E><M><A><W><L><S><K><D><F><E><S><E><R><K><W><K><L><A><Q><A><K><K><V><A><L><R><A><S><K><G><M><L><D><Q><A><S><R><E><E><R><K><L><K><E><E><E><Q><R><L><R><K><V><A><L...
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Probable DNA-dependent ATPase. Not involved in the repression of FLC in gametophytes, but required for the reacti...
Q7X9V2
A7MB46
PCD18_BOVIN
Protocadherin-18
Bos
<M><Y><Q><M><N><A><K><M><H><F><T><F><V><F><A><L><L><V><V><S><F><N><L><D><V><L><G><K><N><L><K><Y><R><I><Y><E><E><Q><R><V><G><S><V><I><A><R><L><S><E><D><V><A><D><V><L><V><K><L><P><N><P><S><T><V><R><F><R><A><M><Q><R><G><N><T><P><L><L><V><V><N><E><D><N><G><E><I><S><I><G><A><K><I><D><R><E><Q><L><C><Q><K><N><L><N><C><S><I><E...
Potential calcium-dependent cell-adhesion protein.<BOP>
A7MB46
C3K1X0
CYSZ_PSEFS
Sulfate transporter CysZ
Pseudomonas
<M><P><A><P><A><L><S><G><P><Q><Y><L><R><E><G><L><K><L><V><L><S><P><G><L><R><L><F><V><L><L><P><L><A><I><N><L><V><L><F><V><G><L><I><Y><F><A><G><H><Q><F><S><L><W><V><D><H><L><M><P><T><L><P><S><W><L><S><F><L><N><Y><L><L><W><P><L><F><V><V><L><V><V><L><M><V><F><F><T><F><T><M><L><A><N><I><I><A><A><P><F><N><G><F><L><S><E><K><V...
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.<BOP>
C3K1X0
Q8TF39
ZN483_HUMAN
Zinc finger protein with KRAB and SCAN domains 16
Homo
<M><Q><A><V><V><P><L><N><K><M><T><A><I><S><P><E><P><Q><T><L><A><S><T><E><Q><N><E><V><P><R><V><V><T><S><G><E><Q><E><A><I><L><R><G><N><A><A><D><A><E><S><F><R><Q><R><F><R><W><F><C><Y><S><E><V><A><G><P><R><K><A><L><S><Q><L><W><E><L><C><N><Q><W><L><R><P><D><I><H><T><K><E><Q><I><L><E><L><L><V><F><E><Q><F><L><T><I><L><P><G><E...
May be involved in transcriptional regulation.<BOP>
Q8TF39
B4S4H8
RRF_PROA2
Ribosome-releasing factor
Prosthecochloris
<M><S><A><R><D><V><I><S><K><G><E><A><K><M><K><K><S><I><E><S><F><Q><H><E><I><A><S><V><R><T><G><K><A><T><T><A><L><L><D><R><V><K><V><D><A><Y><G><Q><Q><M><P><L><K><Q><V><G><N><V><G><V><Q><D><A><H><T><L><M><V><Q><V><W><D><K><S><M><V><A><A><T><E><K><A><I><R><D><A><N><L><G><L><N><P><A><A><E><G><Q><S><I><R><V><S><I><P><P><L><T...
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.<BOP>
B4S4H8
Q8R9C4
RL20_CALS4
50S ribosomal protein L20
Caldanaerobacter
<M><A><R><V><K><S><G><K><V><T><R><R><R><H><K><K><I><L><K><L><A><K><G><Y><W><G><A><K><S><K><L><F><R><V><A><N><Q><A><V><M><K><S><L><M><Y><A><Y><I><G><R><K><L><R><K><R><D><F><R><R><L><W><I><T><R><I><N><A><A><A><R><A><Y><G><I><S><Y><S><R><F><I><N><G><L><K><K><A><G><I><E><I><N><R><K><M><L><S><E><M><A><I><H><D><E><K><A><F><A...
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.<BOP>
Q8R9C4
Q1GBV4
PURA_LACDA
IMP--aspartate ligase
Lactobacillus
<M><T><S><I><A><V><V><G><S><Q><W><G><D><E><G><K><G><K><I><T><D><F><L><G><T><T><A><D><L><S><V><R><A><N><G><G><N><N><A><G><H><T><I><D><F><D><G><K><E><F><K><M><R><L><I><P><S><G><I><F><A><A><K><L><G><A><V><I><S><N><G><V><V><I><N><P><K><V><L><L><G><E><L><N><N><L><E><K><S><G><I><D><T><S><N><L><K><I><S><N><R><A><H><I><I><M><P...
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP>
Q1GBV4
P00300
PLAS_SCEFU
Plastocyanin
Scenedesmus
<D><V><T><V><K><L><G><A><D><S><G><A><L><V><F><E><P><S><S><V><T><I><K><A><G><E><T><V><T><W><V><N><N><A><G><F><P><H><N><I><V><F><D><E><D><E><V><P><S><G><A><N><A><E><A><L><S><H><E><D><Y><L><N><A><P><G><E><S><Y><S><A><K><F><D><T><A><G><T><Y><G><Y><F><C><E><P><H><Q><G><A><G><M><K><G><T><I><T><V><Q>
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.<BOP>
P00300
Q6FZQ9
LIPB_BARQU
Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase
Bartonella
<M><P><F><E><L><K><R><P><D><R><N><H><L><L><H><H><F><K><T><I><P><G><N><P><P><V><E><W><K><I><S><N><N><L><I><E><Y><P><E><A><L><H><Y><M><Q><E><H><V><E><N><I><F><A><Q><N><A><P><E><Q><V><W><L><L><E><H><P><S><L><Y><T><A><G><T><S><A><K><K><K><D><L><L><A><P><H><L><F><P><V><Y><E><A><G><R><G><G><E><F><T><Y><H><G><P><G><Q><R><I><A...
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.<BOP>
Q6FZQ9
G4MWB6
OME1B_MAGO7
ACE1 cytochalasan biosynthesis cluster protein OME1
Pyricularia
<M><S><T><M><A><L><H><R><T><A><S><T><K><S><D><T><T><M><A><C><P><N><G><L><V><K><N><L><P><L><G><G><N><T><K><C><S><A><C><G><S><H><R><A><E><K><R><R><A><S><S><T><S><S><V><S><T><T><P><T><S><P><S><F><S><E><A><D><W><S><P><L><H><N><S><S><Q><E><P><Q><P><E><Y><T><K><V><A><N><S><L><M><R><A><I><T><D><Y><V><G><H><L><Q><N><E><N><L><P...
O-methyltransferase; part of the gene cluster that mediates the biosynthesis of a tyrosine-derived cytochalasan acting as a fungal signal recognized by resistant rice plants and leads to avirulence in Pi33 resistant rice cultivars . The first step in the pathway is catalyzed by the hybrid PKS-NRPS ACE1, assisted by the...
G4MWB6
A7X396
CLPX_STAA1
ATP-dependent Clp protease ATP-binding subunit ClpX
Staphylococcus
<M><F><K><F><N><E><D><E><E><N><L><K><C><S><F><C><G><K><D><Q><D><Q><V><K><K><L><V><A><G><S><G><V><Y><I><C><N><E><C><I><E><L><C><S><E><I><V><E><E><E><L><A><Q><N><T><S><E><A><M><T><E><L><P><T><P><K><E><I><M><D><H><L><N><E><Y><V><I><G><Q><E><K><A><K><K><S><L><A><V><A><V><Y><N><H><Y><K><R><I><Q><Q><L><G><P><K><E><D><D><V><E...
ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.<BOP>
A7X396
Q5X2V3
RF1_LEGPA
Peptide chain release factor 1
Legionella
<M><K><K><S><L><E><L><K><L><Q><Q><M><L><E><R><Y><E><E><V><G><R><L><L><S><E><A><S><I><I><A><D><Q><N><Q><F><K><S><L><S><K><E><Y><A><Q><L><E><P><V><S><Q><C><Y><E><S><Y><L><E><A><K><N><N><L><D><S><L><N><E><L><L><E><S><D><D><K><D><L><A><T><M><A><E><E><E><I><D><T><V><K><K><Q><I><E><E><L><D><E><Q><L><Q><W><H><L><I><P><K><D><P...
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.<BOP>
Q5X2V3
Q9M9U0
XXT4_ARATH
Putative glycosyltransferase 4
Arabidopsis
<M><F><Q><D><G><S><R><S><S><G><S><G><R><G><L><S><T><T><A><V><S><N><G><G><W><R><T><R><G><F><L><R><G><W><Q><I><Q><N><T><L><F><N><N><I><K><F><M><I><L><C><C><F><V><T><I><L><I><L><L><G><T><I><R><V><G><N><L><G><S><S><N><A><D><S><V><N><Q><S><F><I><K><E><T><I><P><I><L><A><E><I><P><S><D><S><H><S><T><D><L><A><E><P><P><K><A><D><V...
Xylosyltransferase specific to UDP-D-xylose that accepts cellohexaose as substrate to produce xyloglucan.<BOP>
Q9M9U0
Q5WDH6
HISZ_ALKCK
ATP phosphoribosyltransferase regulatory subunit
Alkalihalobacillus
<M><S><E><P><F><M><F><E><K><P><L><G><M><R><D><V><L><P><N><L><H><S><M><Q><R><K><L><G><D><R><V><L><Q><E><F><R><L><W><G><Y><E><Q><V><Q><T><P><T><L><E><Y><Y><E><T><V><G><K><A><S><A><I><S><D><K><Q><L><F><K><L><I><D><F><H><G><N><T><L><V><L><R><P><D><M><T><A><P><I><A><R><L><V><S><S><S><M><K><D><I><P><Y><P><L><R><L><S><Y><C><S...
Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.<BOP>
Q5WDH6
Q8VY74
U1135_ARATH
U11/U12 small nuclear ribonucleoprotein 35 kDa protein
Arabidopsis
<M><S><G><G><G><N><N><V><V><N><K><V><F><Y><A><T><S><Y><H><P><I><Q><A><G><S><I><D><G><T><D><V><A><P><H><D><N><G><V><R><R><A><L><L><C><Y><N><A><G><L><Y><D><P><S><G><D><S><K><A><V><G><D><P><Y><C><T><L><F><V><G><R><L><S><H><H><T><T><E><D><T><L><R><E><V><M><S><K><Y><G><R><I><K><N><L><R><L><V><R><H><I><V><T><G><A><S><R><G><Y...
May facilitate 5' splice site recognition in the minor spliceosome. May be involved in interactions with components of the major spliceosome bound to the pyrimidine tract of an upstream U2-type intron.<BOP>
Q8VY74
A6UPN7
BIOB_METVS
Biotin synthase
Methanococcus
<M><N><E><R><K><L><N><K><D><F><L><E><I><Y><E><M><S><I><S><G><K><I><K><K><E><D><A><L><E><I><L><K><L><D><V><Y><D><L><L><H><I><S><Y><H><L><K><K><A><F><N><K><E><K><I><E><T><C><S><I><I><N><A><K><S><G><F><C><S><E><N><C><N><F><C><S><Q><S><I><H><N><N><S><K><I><N><I><Y><G><L><K><S><K><E><E><I><L><K><S><A><K><S><I><E><N><Y><S><N...
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.<BOP>
A6UPN7
Q7Y228
LAMP1_ARATH
Protein LIKE AMP1
Arabidopsis
<M><S><K><S><K><S><L><A><F><V><I><A><A><L><S><Y><S><F><F><S><L><F><S><S><P><P><K><S><H><Y><H><E><L><F><I><S><T><S><F><S><D><N><A><S><V><A><L><N><L><H><T><L><T><R><R><P><H><V><A><G><T><V><A><N><A><E><A><A><E><Y><V><R><S><V><F><T><S><S><A><L><K><S><H><V><V><A><Y><Q><V><S><L><T><Y><P><V><H><R><S><L><V><L><T><P><T><D><S><A...
Acts in association with AMP1 to suppress ectopic stem cell niche formation in the shoot apical meristem (SAM) independently of cytokinin signaling pathway.<BOP>
Q7Y228
Q4FVP8
ERPA_PSYA2
Iron-sulfur cluster insertion protein ErpA
Psychrobacter
<M><N><Q><P><A><N><Q><F><N><P><S><S><S><Q><P><V><D><P><T><V><L><N><L><T><D><S><A><A><Q><K><V><R><R><L><R><E><E><E><G><D><S><N><L><M><L><R><V><Y><V><T><G><G><G><C><S><G><F><S><Y><G><F><N><F><A><N><E><L><N><E><D><D><A><N><F><D><N><N><D><V><T><L><V><V><D><S><L><S><Y><Q><Y><L><Q><G><S><T><V><D><Y><T><E><G><L><E><G><A><R><F...
Required for insertion of 4Fe-4S clusters for at least IspG.<BOP>
Q4FVP8
Q05209
PTN12_HUMAN
Protein-tyrosine phosphatase G1
Homo
<M><E><Q><V><E><I><L><R><K><F><I><Q><R><V><Q><A><M><K><S><P><D><H><N><G><E><D><N><F><A><R><D><F><M><R><L><R><R><L><S><T><K><Y><R><T><E><K><I><Y><P><T><A><T><G><E><K><E><E><N><V><K><K><N><R><Y><K><D><I><L><P><F><D><H><S><R><V><K><L><T><L><K><T><P><S><Q><D><S><D><Y><I><N><A><N><F><I><K><G><V><Y><G><P><K><A><Y><V><A><T><Q...
Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades . Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2 . Selectively dephosphorylates ERBB2 phosphorylated at 'Tyr-1112', 'Tyr-1196', and/or 'Tyr-1248' .<...
Q05209
B5FKN5
DCTA_SALDC
C4-dicarboxylate transport protein
Salmonella
<M><K><T><S><L><F><K><S><L><Y><F><Q><V><L><T><A><I><A><I><G><I><L><L><G><H><Y><Y><P><E><L><G><A><Q><M><K><P><L><G><D><A><F><V><K><L><I><K><M><I><I><A><P><V><I><F><C><T><V><V><T><G><I><A><G><M><E><S><M><K><A><V><G><R><T><G><A><V><A><L><L><Y><F><E><I><V><S><T><I><A><L><I><I><G><L><I><I><V><N><V><V><Q><P><G><A><G><M><N><V...
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.<BOP>
B5FKN5
A0PXK7
SP5G_CLONN
Putative septation protein SpoVG
Clostridium
<M><Q><I><T><D><V><R><I><R><K><I><S><A><E><G><K><M><K><A><I><V><S><V><T><F><D><N><E><F><V><V><H><D><I><K><V><I><E><G><Q><N><G><L><F><I><A><M><P><S><R><K><T><P><T><G><E><F><K><D><I><A><H><P><I><N><T><E><T><R><Q><K><I><Q><K><A><I><L><D><E><Y><E><V><V><K><N><E><T><T><N><N><E><N><G><E><E><I><T><S><E><D>
Could be involved in septation.<BOP>
A0PXK7
O30461
HYPA_NOSS1
Hydrogenase maturation factor HypA
Nostoc
<M><H><E><L><G><I><T><Q><N><I><V><A><I><V><S><E><Y><A><Q><G><S><K><V><N><R><I><L><L><E><I><G><K><L><S><A><I><M><P><D><A><V><Q><F><C><F><D><I><C><S><K><G><T><S><L><E><G><A><V><L><E><I><R><E><I><P><G><L><A><K><C><R><Q><C><G><A><E><I><A><L><E><K><P><F><G><I><C><G><C><G><S><V><H><L><D><V><I><T><G><E><E><L><K><I><K><E><I><E...
Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.<BOP>
O30461