accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q74MV1 | PCNA_NANEQ | Proliferating cell nuclear antigen homolog | Nanoarchaeum | <M><R><V><T><F><P><D><A><K><A><L><K><K><I><V><P><I><V><A><D><L><I><S><E><G><Q><F><V><A><T><E><E><G><I><K><L><V><A><M><D><P><A><S><I><A><M><V><I><W><E><M><K><P><E><A><F><I><D><Y><T><I><E><G><D><K><E><I><I><T><V><S><M><D><D><L><K><T><I><V><K><K><L><K><Q><R><E><M><V><V><W><E><T><D><R><E><K><N><K><L><K><I><L><A><R><G><T><I... | Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.<BOP> | Q74MV1 |
P33575 | LAMP_PETMA | Cartilage matrix protein | Petromyzon | <M><A><A><A><I><Q><A><L><L><V><L><A><L><L><H><L><A><T><A><T><P><V><I><G><K><Q><T><V><S><T><L><S><T><G><Y><L><G><H><P><V><V><G><G><L><G><Y><G><G><L><G><Y><G><G><L><G><V><A><G><L><G><V><A><G><L><G><Y><G><G><L><G><Y><P><G><A><A><L><G><G><V><Y><T><H><H><A><A><G><L><V><H><P><Y><G><G><L><G><Y><H><A><A><P><Y><H><H><A><L><G><G... | Self-aggregating protein that is part of the soluble form of lamprin.<BOP> | P33575 |
Q08967 | FLC1_YEAST | TRP-like ion channel protein FLC1 | Saccharomyces | <M><Q><V><L><V><T><L><W><C><L><I><C><T><C><L><V><L><P><V><A><A><K><K><R><T><L><T><A><S><S><L><V><T><C><M><E><N><S><Q><L><S><A><N><S><F><D><V><S><F><S><P><D><D><R><S><L><H><Y><D><L><D><M><T><T><Q><I><D><S><Y><I><Y><A><Y><V><D><V><Y><A><Y><G><F><K><I><I><T><E><N><F><D><V><C><S><M><G><W><K><Q><F><C><P><V><H><P><G><N><I><Q... | May be responsible for the transport of FAD into the endoplasmic reticulum lumen, where it is required for oxidative protein folding.<BOP> | Q08967 |
Q6MFA3 | MNME_PARUW | tRNA modification GTPase MnmE | Candidatus Protochlamydia | <M><E><F><I><H><Q><P><Y><Y><P><G><E><T><I><A><A><I><A><T><P><P><G><E><G><G><V><A><I><I><R><I><S><G><D><Q><S><L><E><V><A><A><K><I><F><S><G><P><I><F><S><Y><R><S><H><T><A><H><Y><G><Q><I><Y><N><S><S><G><E><H><V><D><D><V><L><V><L><I><M><L><G><K><R><S><Y><T><G><E><N><T><V><E><I><H><C><H><G><G><S><L><I><T><R><K><V><L><E><V><V... | Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP> | Q6MFA3 |
P20143 | PSAH_HORVU | Light-harvesting complex I 11 kDa protein | Hordeum | <M><A><S><L><V><A><V><Q><P><A><A><V><K><G><L><S><G><S><S><I><S><G><R><K><L><A><V><R><P><S><S><A><A><V><S><R><S><T><R><R><A><R><G><A><A><V><V><A><K><Y><G><E><K><S><V><Y><F><D><L><D><D><I><A><N><T><T><G><Q><W><D><L><Y><G><S><D><A><P><S><P><Y><N><G><L><Q><S><K><F><F><N><T><F><A><A><P><F><T><K><R><G><L><L><L><K><F><L><L><I... | Possible role could be the docking of the LHC I antenna complex to the core complex.<BOP> | P20143 |
Q74IS4 | RIMP_LACJO | Ribosome maturation factor RimP | Lactobacillus | <M><T><K><V><T><E><L><V><A><D><V><V><T><P><L><A><E><A><R><G><D><E><L><V><D><V><E><Y><V><K><E><K><K><Q><Y><Y><L><R><I><Y><V><D><R><R><P><G><G><I><D><I><E><E><I><A><N><L><S><E><L><V><S><E><K><L><D><E><L><D><P><D><P><F><P><E><P><Y><I><L><E><L><S><S><P><G><L><E><R><P><I><K><N><E><K><D><W><E><R><A><K><G><S><Y><I><H><V><S><L... | Required for maturation of 30S ribosomal subunits.<BOP> | Q74IS4 |
A4Y1A4 | DNAA_SHEPC | Chromosomal replication initiator protein DnaA | Shewanella | <M><A><V><S><L><W><Q><Q><C><I><G><R><L><Q><D><E><L><P><A><Q><Q><F><S><M><W><I><R><P><L><Q><A><E><M><D><G><D><T><L><V><L><Y><A><P><N><R><F><V><L><D><W><V><R><E><K><Y><I><N><I><I><N><Q><F><F><T><E><Q><M><G><S><D><A><P><K><L><R><F><D><I><G><S><R><P><S><A><K><K><F><E><P><A><P><V><A><T><V><R><A><P><N><T><Q><T><K><A><T><V><G... | Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.<BOP> | A4Y1A4 |
Q5FHA4 | DXR_EHRRG | 2-C-methyl-D-erythritol 4-phosphate synthase | Ehrlichia | <M><K><T><V><S><I><F><G><S><T><G><A><I><G><Q><M><I><I><D><V><I><L><A><S><S><D><S><Y><Q><V><K><A><L><V><A><K><S><N><V><Q><L><L><A><F><Q><A><K><V><V><N><A><E><M><V><V><I><A><D><V><G><L><Y><K><E><L><K><D><L><L><F><G><T><N><V><K><I><S><V><G><D><V><G><M><Q><M><A><A><S><L><N><V><D><Y><V><M><M><A><I><V><G><I><A><A><L><V><P><M... | Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).<BOP> | Q5FHA4 |
C3MEJ2 | HRCA_SINFN | Heat-inducible transcription repressor HrcA | Sinorhizobium | <M><V><L><R><N><P><E><K><K><G><I><A><S><T><L><D><E><R><S><G><E><I><F><R><R><I><V><E><T><Y><L><E><S><G><E><P><L><G><S><R><N><L><S><R><L><L><P><M><S><L><S><P><A><S><V><R><N><V><M><S><D><L><E><D><L><G><L><I><Y><S><P><H><V><S><A><G><R><L><P><T><Q><T><G><L><R><F><F><V><D><A><F><M><Q><V><G><N><L><S><A><E><E><R><T><S><I><E><R... | Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.<BOP> | C3MEJ2 |
Q72AU1 | RECO_DESVH | Recombination protein O | Desulfovibrio | <M><D><F><T><D><Q><A><L><V><L><R><V><G><R><F><R><E><A><D><L><W><V><R><F><L><C><R><Q><R><G><I><I><S><A><F><A><F><G><G><C><R><S><R><R><R><F><C><G><C><L><D><I><F><N><V><V><L><M><R><V><Q><G><T><R><G><G><L><Y><Q><S><L><Q><E><A><T><L><L><K><G><P><D><R><L><R><R><D><W><R><R><Y><G><V><A><V><N><C><L><R><F><I><E><A><L><G><A><G><P... | Involved in DNA repair and RecF pathway recombination.<BOP> | Q72AU1 |
B0BQ12 | PURA_ACTPJ | IMP--aspartate ligase | Actinobacillus | <M><G><K><S><V><A><I><L><G><A><Q><W><G><D><E><G><K><G><K><I><V><D><L><L><T><D><R><V><K><Y><V><V><R><Y><Q><G><G><H><N><A><G><H><T><L><I><I><N><G><E><K><T><V><L><R><L><I><P><S><G><I><L><R><D><N><V><T><C><L><I><G><N><G><V><V><L><S><P><E><A><L><M><K><E><M><G><E><L><E><A><R><G><I><N><V><R><D><R><L><K><I><S><E><A><C><P><L><I... | Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP> | B0BQ12 |
P11715 | CP17A_RAT | Steroid 17-alpha-monooxygenase | Rattus | <M><W><E><L><V><G><L><L><L><L><I><L><A><Y><F><F><W><V><K><S><K><T><P><G><A><K><L><P><R><S><L><P><S><L><P><L><V><G><S><L><P><F><L><P><R><R><G><H><M><H><V><N><F><F><K><L><Q><E><K><Y><G><P><I><Y><S><L><R><L><G><T><T><T><T><V><I><I><G><H><Y><Q><L><A><R><E><V><L><I><K><K><G><K><E><F><S><G><R><P><Q><M><V><T><Q><S><L><L><S><D... | A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal gl... | P11715 |
Q48BY7 | PCKA_PSE14 | Phosphoenolpyruvate carboxykinase (ATP) | Pseudomonas | <M><T><Q><I><N><N><A><V><H><T><D><L><S><T><D><E><L><V><K><E><A><L><A><R><N><E><G><V><L><S><D><T><G><A><L><V><V><E><T><G><H><R><T><G><R><S><P><V><D><R><F><I><V><E><E><P><S><T><Q><D><A><I><A><W><G><P><I><N><R><K><F><P><A><E><K><F><D><A><L><W><N><R><V><G><A><Y><L><A><E><R><E><R><F><V><S><H><V><H><V><G><S><D><P><A><H><Y><L... | Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.<BOP> | Q48BY7 |
P54720 | CATD_BACSU | Putative oxidoreductase CatD | Bacillus | <M><N><K><S><F><E><I><G><T><L><L><L><R><V><I><T><G><I><I><F><F><V><H><G><L><S><K><F><Q><G><M><E><G><T><I><Q><F><F><G><S><I><G><L><P><S><F><M><A><Y><V><I><A><A><I><E><L><I><G><G><V><L><V><F><F><G><L><A><T><R><I><V><G><V><L><F><A><L><T><L><I><G><A><I><I><T><V><K><L><K><A><P><F><M><G><N><A><E><F><D><Y><L><L><L><L><T><S><I... | Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol.<BOP> | P54720 |
A4YVD5 | TRPD_BRASO | Anthranilate phosphoribosyltransferase | unclassified Bradyrhizobium | <M><D><D><L><K><S><I><I><G><K><V><A><T><G><A><P><L><S><R><E><Q><A><A><S><A><F><D><S><M><M><S><G><E><A><T><P><S><Q><M><G><A><L><L><M><A><L><R><V><R><G><E><T><V><E><E><I><T><G><A><V><S><V><M><R><A><K><M><L><R><V><D><A><P><A><N><A><V><D><I><V><G><T><G><G><D><G><S><G><S><V><N><V><S><T><C><A><S><F><I><V><A><G><A><G><V><P><V... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | A4YVD5 |
Q9S7B2 | RS2_MAIZE | ZmPHAN | Zea | <M><K><E><R><Q><R><W><R><P><E><E><D><A><V><L><R><A><Y><V><R><Q><Y><G><P><R><E><W><H><L><V><S><Q><R><M><N><V><A><L><D><R><D><A><K><S><C><L><E><R><W><K><N><Y><L><R><P><G><I><K><K><G><S><L><T><E><E><E><Q><R><L><V><I><R><L><Q><A><K><H><G><N><K><W><K><K><I><A><A><E><V><P><G><R><T><A><K><R><L><G><K><W><W><E><V><F><K><E><K><Q... | Transcription factor required for normal cell differentiation. Interacts directly with asymmetric leaves 2 (AS2) to repress the knox homeobox genes.<BOP> | Q9S7B2 |
A1SA22 | MIAA_SHEAM | Isopentenyl-diphosphate:tRNA isopentenyltransferase | Shewanella | <M><T><S><L><P><K><V><L><F><L><M><G><P><T><A><S><G><K><T><A><L><A><L><D><M><A><E><H><H><N><C><E><I><I><S><V><D><S><A><L><I><Y><R><G><M><D><I><G><T><A><K><P><T><A><S><E><L><A><R><A><P><H><K><L><I><D><I><L><D><P><L><E><S><Y><S><A><A><D><F><R><A><D><A><V><R><E><I><E><E><T><L><S><R><G><K><T><P><L><L><V><G><G><T><M><M><Y><F... | Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).<BOP> | A1SA22 |
Q68WE9 | IPYR_RICTY | Pyrophosphate phospho-hydrolase | typhus group | <M><F><I><D><K><I><K><A><K><A><N><N><N><E><I><N><V><I><I><E><I><P><M><N><S><G><P><I><K><Y><E><F><D><K><E><S><G><A><I><F><V><D><R><F><M><Q><T><T><M><S><Y><P><C><N><Y><G><F><I><P><D><T><L><S><N><D><G><D><P><V><D><V><L><V><V><A><H><H><P><V><V><P><G><S><V><I><K><C><R><A><I><G><V><L><M><M><E><D><E><S><G><L><D><E><K><I><I><A... | Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.<BOP> | Q68WE9 |
A4QLA2 | PSBC_LEPVR | Protein CP-43 | Lepidium | <M><K><T><L><Y><S><L><R><R><F><Y><H><V><E><T><L><F><N><G><T><L><A><L><A><G><R><D><Q><E><T><T><G><F><A><W><W><A><G><N><A><R><L><I><N><L><S><G><K><L><L><G><A><H><V><A><H><A><G><L><I><V><F><W><A><G><A><M><N><L><F><E><V><A><H><F><V><P><E><K><P><M><Y><E><Q><G><L><I><L><L><P><H><L><A><T><L><G><W><G><V><G><P><G><G><E><V><I><D... | One of the components of the core complex of photosystem II (PSII). It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII. PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient sub... | A4QLA2 |
Q87CY6 | THIC_XYLFT | Thiamine biosynthesis protein ThiC | Xylella | <M><N><I><T><T><A><L><P><L><P><T><H><L><L><S><E><K><V><T><A><P><L><L><G><A><R><K><I><Y><V><T><G><S><R><Q><D><I><R><V><P><M><R><E><I><A><L><T><P><S><S><A><R><Y><G><G><N><E><N><L><S><L><V><L><Y><D><T><S><G><I><Y><T><D><P><Q><A><T><I><D><L><A><C><G><L><P><R><L><R><T><A><W><I><D><E><R><A><D><T><V><E><A><K><L><H><F><K><V><P... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | Q87CY6 |
A9FST8 | MIAB_SORC5 | tRNA-i(6)A37 methylthiotransferase | Sorangium | <M><P><R><Y><S><I><T><T><F><G><C><Q><M><N><V><H><D><S><E><R><M><H><D><V><L><R><C><A><G><Y><T><E><A><G><S><A><D><E><A><D><V><L><V><L><N><T><C><S><V><R><E><K><A><E><Q><K><L><R><S><E><V><G><R><L><A><R><W><K><R><E><R><A><D><R><V><L><V><V><A><G><C><V><A><Q><Q><E><G><E><R><L><L><K><Q><M><R><A><I><D><V><V><V><G><P><D><N><I><P... | Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.<BOP> | A9FST8 |
Q88WJ1 | RL19_LACPL | 50S ribosomal protein L19 | Lactiplantibacillus | <M><R><Q><N><Q><L><I><E><K><I><T><N><E><Q><L><R><T><D><I><P><D><F><R><A><G><D><T><V><R><V><H><A><R><V><V><E><G><T><R><E><R><I><Q><L><F><E><G><V><V><I><K><R><H><G><S><G><I><S><E><T><Y><T><V><R><K><I><S><N><G><V><G><V><E><R><T><F><P><L><H><T><P><R><V><A><A><I><D><V><V><R><Q><G><R><V><R><R><A><K><L><Y><Y><L><R><N><L><H><G... | This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.<BOP> | Q88WJ1 |
Q3IK95 | RF1_PSET1 | Peptide chain release factor 1 | Pseudoalteromonas | <M><K><E><S><V><Y><H><K><L><E><I><L><V><E><R><Y><E><E><V><Q><A><L><L><S><D><P><S><V><I><R><D><Q><N><R><F><R><A><L><S><K><E><Y><S><D><L><E><E><V><V><K><T><F><L><S><Y><Q><Q><A><Q><Q><D><V><I><S><A><E><E><M><L><K><D><S><D><P><D><I><R><E><M><A><Q><E><E><Y><K><E><A><K><A><Q><I><L><T><I><E><D><E><I><Q><V><L><M><L><P><K><D><P... | Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.<BOP> | Q3IK95 |
Q89AL1 | RLUB_BUCBP | rRNA-uridine isomerase B | Buchnera | <M><C><E><K><I><Q><K><I><L><A><R><H><G><Y><G><S><R><R><Y><I><E><S><L><I><K><S><H><S><V><K><I><N><D><E><V><V><K><V><G><Q><R><I><S><I><N><V><I><Q><K><V><I><I><N><N><N><N><Y><K><P><K><L><N><I><N><K><S><L><K><V><L><L><Y><N><K><P><E><G><E><I><C><T><R><K><D><Q><R><N><R><R><T><I><F><E><K><L><P><K><L><S><N><A><R><W><I><N><I><G... | Responsible for synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA.<BOP> | Q89AL1 |
Q82SM6 | QUEF_NITEU | PreQ(0) reductase | Nitrosomonas | <M><T><T><Q><P><S><K><Q><L><E><T><F><E><N><P><V><Q><T><R><D><Y><R><I><H><M><E><I><P><E><F><T><C><L><C><P><K><T><G><Q><P><D><F><A><R><L><T><L><D><Y><I><P><D><K><K><C><I><E><L><K><S><L><K><L><Y><I><W><S><Y><R><D><E><G><A><F><H><E><A><V><T><N><R><I><L><D><D><L><V><A><A><M><K><P><R><F><I><R><L><T><S><K><F><Y><V><R><G><G><I... | Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).<BOP> | Q82SM6 |
Q01872 | KRUP_LITFO | Protein krueppel | Lithobius | <M><R><L><H><T><G><E><K><P><Y><H><C><T><H><C><E><R><Q><F><V><Q><V><A><N><L><R><R><H><L><R><V><H><T><G><E><R><P><Y><A><C><E><L><C><T><S><K> | Krueppel is a gap class segmentation protein.<BOP> | Q01872 |
B4UCB2 | BIOB_ANASK | Biotin synthase | unclassified Anaeromyxobacter | <M><C><E><T><A><S><T><T><L><P><P><G><I><T><P><I><S><G><D><E><A><R><R><L><I><H><H><T><S><G><P><E><L><E><A><L><L><D><R><A><E><A><V><R><R><A><V><H><G><D><E><V><A><L><C><G><I><T><N><A><K><S><G><R><C><P><E><D><C><G><F><C><S><Q><S><A><R><F><E><G><A><D><A><P><V><Y><P><M><I><G><A><G><E><I><V><E><Q><A><H><K><A><E><R><A><G><A><R... | Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.<BOP> | B4UCB2 |
Q10045 | UNC50_CAEEL | Uncoordinated protein 50 | Caenorhabditis | <M><S><S><Q><P><R><G><S><G><T><Q><P><G><P><S><Q><S><P><I><S><Q><R><N><F><R><Y><E><P><A><R><S><G><Y><T><S><P><G><Q><Y><S><T><Y><S><T><S><T><A><D><R><V><G><C><L><T><A><V><R><M><S><A><F><A><K><L><S><R><F><T><R><R><L><V><H><I><R><Q><M><D><F><E><F><A><L><W><Q><M><L><Y><L><L><I><Q><P><S><K><V><Y><K><N><F><I><Y><R><K><R><T><K... | Required for cell surface expression of acetylcholine receptors in body-wall muscles.<BOP> | Q10045 |
Q3A1D6 | RL21_SYNC1 | 50S ribosomal protein L21 | Syntrophotalea | <M><Y><A><V><I><K><T><G><G><K><Q><Y><K><V><S><E><G><D><L><V><K><I><E><K><I><E><G><A><V><G><D><T><I><E><L><D><E><V><L><M><V><G><G><E><E><V><K><I><G><T><P><L><L><P><G><A><K><V><T><A><R><I><V><Q><Q><G><K><D><K><K><V><L><V><F><H><S><K><R><R><K><G><Y><R><K><T><Y><G><H><R><Q><P><I><T><R><L><Q><I><T><G><I><E><A> | This protein binds to 23S rRNA in the presence of protein L20.<BOP> | Q3A1D6 |
B6YQ10 | RL9_AZOPC | 50S ribosomal protein L9 | Candidatus Azobacteroides | <M><Q><V><I><L><L><E><N><V><D><K><L><G><Y><K><D><D><I><V><T><V><K><N><G><Y><G><R><N><F><L><I><P><K><K><K><A><I><F><A><S><K><T><A><K><K><V><L><A><E><N><L><R><Q><Q><V><R><K><L><E><K><I><K><K><D><A><Q><T><L><A><N><K><L><M><N><I><S><L><T><I><G><A><K><T><S><S><N><G><I><I><F><G><S><I><T><N><I><Q><I><A><D><E><L><A><K><K><G><V... | Binds to the 23S rRNA.<BOP> | B6YQ10 |
P53380 | MSCL_CLOPE | Large-conductance mechanosensitive channel | Clostridium | <M><W><K><E><F><K><E><F><A><M><K><G><N><V><I><D><L><A><I><G><V><I><I><G><G><A><F><G><K><I><V><T><S><L><V><N><D><I><I><M><P><V><I><G><R><L><V><G><K><V><D><F><S><N><L><Y><I><N><L><S><G><Q><Q><F><N><S><L><Q><E><A><Q><A><A><G><A><A><T><I><N><Y><G><L><F><L><N><N><L><I><N><F><L><I><I><A><F><S><I><F><I><A><I><K><Q><I><N><K><L... | Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.<BOP> | P53380 |
A6LRN5 | DNAJ_CLOB8 | Chaperone protein DnaJ | Clostridium | <M><A><N><K><D><Y><Y><E><L><L><G><L><Q><K><G><A><S><D><D><E><I><K><R><A><F><R><K><L><A><V><K><Y><H><P><D><R><N><Q><G><N><A><E><A><E><E><K><F><K><E><I><N><E><A><Y><Q><V><L><S><D><P><E><K><K><A><K><Y><D><Q><F><G><S><A><A><F><D><G><S><G><G><F><G><G><G><G><F><G><G><F><D><G><F><D><M><G><G><F><G><D><I><F><E><S><F><F><G><G><G... | Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bou... | A6LRN5 |
Q9LGE3 | FLP1_ORYSJ | Protein ROOT ARCHITECTURE ASSOCIATED 1 | Oryza sativa | <M><S><G><V><W><V><F><K><N><G><V><V><R><L><V><E><K><Q><Q><A><T><A><G><T><A><V><A><G><G><R><R><K><A><L><V><H><T><P><S><G><Q><V><V><S><S><Y><A><A><L><E><A><R><L><T><A><L><G><W><E><R><Y><Y><E><D><P><S><L><F><Q><F><H><K><R><G><S><L><D><L><I><S><L><P><A><D><F><S><A><F><S><S><V><H><M><Y><D><I><V><V><K><N><R><D><S><F><R><V><V... | GTP-binding protein that functions in the development of root systems, which are mediated by auxin. Acts as a cell cycle regulator during root development. Proteasome-mediated degradation of the protein is necessary for the transition of metaphase to anaphase in mitosis.<BOP> | Q9LGE3 |
B2S1C4 | NADD_BORHD | Nicotinate mononucleotide adenylyltransferase | Borrelia | <M><R><I><A><I><L><G><G><T><Y><N><P><V><H><I><G><H><M><F><L><A><K><E><L><E><H><F><L><N><V><D><K><I><L><F><I><P><T><H><K><P><V><H><K><R><V><E><N><I><S><V><K><D><R><I><A><M><L><K><L><A><V><Q><H><E><K><N><M><F><I><D><E><C><D><I><V><N><G><G><I><T><Y><T><V><D><T><I><A><C><I><K><N><K><Y><V><H><D><D><I><Y><L><V><I><G><D><D><L... | Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).<BOP> | B2S1C4 |
A5EVM2 | RL20_DICNV | 50S ribosomal protein L20 | Dichelobacter | <M><A><R><V><K><R><G><V><Q><A><H><A><R><H><K><K><V><L><K><A><A><K><G><Y><Y><S><A><R><R><K><T><F><R><V><A><K><Q><A><V><I><K><A><G><Q><Y><A><Y><R><D><R><K><T><K><K><R><Q><F><R><Q><L><W><I><I><R><I><N><A><G><A><R><I><H><G><L><S><Y><S><R><F><I><N><G><L><K><K><S><G><I><A><V><D><R><K><I><L><S><E><L><A><V><Y><D><K><S><V><F><A... | Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.<BOP> | A5EVM2 |
Q182F0 | HRCA_CLOD6 | Heat-inducible transcription repressor HrcA | Clostridioides | <M><E><L><N><E><R><K><L><N><I><L><K><A><I><V><K><D><Y><I><E><T><A><E><A><I><G><S><R><T><I><S><K><R><H><D><L><G><V><S><A><A><T><I><R><N><E><M><A><D><L><E><E><L><G><Y><L><I><Q><P><H><T><S><A><G><R><V><P><S><E><K><G><Y><K><L><Y><V><N><S><L><M><S><K><S><E><L><D><D><N><D><K><I><L><I><E><Q><C><M><N><H><N><I><N><H><I><K><E><L... | Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.<BOP> | Q182F0 |
Q82ZW6 | SYV_ENTFA | Valyl-tRNA synthetase | Enterococcus | <M><S><E><E><K><N><L><P><T><K><Y><Q><P><T><E><I><E><A><G><R><Y><Q><K><W><L><D><Q><D><L><F><K><P><S><G><D><K><K><A><K><P><Y><S><I><V><I><P><P><P><N><V><T><G><K><L><H><L><G><H><A><W><D><T><T><L><Q><D><M><I><I><R><Q><K><R><M><Q><G><F><D><T><L><W><L><P><G><M><D><H><A><G><I><A><T><Q><A><K><V><E><E><K><L><A><Q><Q><G><I><S><R... | Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.<BOP> | Q82ZW6 |
Q040N1 | DLTC_LACGA | D-alanine--poly(phosphoribitol) ligase subunit 2 | Lactobacillus | <M><D><T><K><Q><A><V><L><D><I><L><N><E><L><T><G><E><D><L><S><D><Q><M><D><E><N><I><F><E><N><G><L><L><D><S><M><A><T><V><Q><M><L><L><E><L><Q><D><K><C><G><V><T><A><P><V><S><E><F><H><R><E><D><W><D><T><P><N><K><I><I><A><K><V><E><S><L><R><N><E> | Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, proba... | Q040N1 |
Q2TBN9 | IFT43_BOVIN | Intraflagellar transport protein 43 homolog | Bos | <M><E><D><L><L><D><L><G><E><E><R><R><R><C><P><A><T><S><G><A><K><M><G><R><R><A><Q><Q><E><S><T><Q><A><E><N><H><L><S><G><K><N><S><S><L><T><L><T><A><E><V><P><P><P><K><P><P><R><R><Q><G><R><W><A><E><A><S><V><K><V><S><K><S><Q><R><R><A><S><E><E><I><Q><D><H><R><L><R><Q><Q><S><L><D><R><S><D><D><G><G><D><I><P><V><I><P><D><L><E><E... | As a component of IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis. Involved in retrograde ciliary transport along microtubules from the ciliary tip to the base.<BOP> | Q2TBN9 |
Q7ULP3 | HIS5_RHOBA | ImGP synthase subunit HisH | Rhodopirellula | <M><I><T><I><V><D><Y><Q><M><G><N><L><R><S><V><Q><K><A><V><E><R><S><G><V><E><A><E><I><T><S><D><A><S><Q><I><A><A><A><E><R><L><I><L><P><G><V><G><A><F><G><D><A><I><G><E><I><R><R><R><D><L><E><K><P><I><K><D><F><I><A><S><G><K><P><F><L><G><I><C><L><G><L><Q><M><L><F><E><Q><G><F><E><G><G><T><H><E><G><L><G><V><L><G><G><D><V><V><A... | IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.<BOP> | Q7ULP3 |
P59228 | VATL2_ARATH | Vacuolar proton pump subunit c2 | Arabidopsis | <M><A><S><T><F><S><G><D><E><T><A><P><F><F><G><F><L><G><A><A><A><A><L><V><F><S><C><M><G><A><A><Y><G><T><A><K><S><G><V><G><V><A><S><M><G><V><M><R><P><E><L><V><M><K><S><I><V><P><V><V><M><A><G><V><L><G><I><Y><G><L><I><I><A><V><I><I><S><T><G><I><N><P><K><A><K><S><Y><Y><L><F><D><G><Y><A><H><L><S><S><G><L><A><C><G><L><A><G><L... | Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.<BOP> | P59228 |
P96038 | RL1_SACS2 | 50S ribosomal protein L1 | Saccharolobus | <M><Q><I><V><D><R><S><N><L><E><A><S><L><K><L><A><L><S><P><E><N><N><P><K><R><N><F><V><Q><S><V><E><I><I><V><T><F><K><E><V><D><M><K><K><G><D><L><K><L><R><E><I><V><V><L><P><K><P><P><E><K><T><K><K><V><L><V><V><P><T><I><Q><Q><L><E><Y><A><K><K><A><E><P><N><T><I><L><T><K><E><E><L><Q><K><L><Q><G><N><K><R><A><I><K><K><I><A><R><Q... | Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.<BOP> | P96038 |
P0A4J1 | SODM_LACLA | Superoxide dismutase [Mn] | Lactococcus | <M><A><F><T><L><P><E><L><P><Y><A><P><N><A><L><E><P><F><F><D><E><A><T><M><R><L><H><H><G><K><H><H><Q><T><Y><V><N><N><L><N><A><A><I><E><K><H><N><E><L><D><D><L><S><L><E><E><L><L><T><D><L><S><A><I><P><E><D><I><R><T><A><V><R><N><N><G><G><G><H><L><N><H><S><Q><F><W><L><W><L><R><P><N><T><D><G><S><E><N><H><A><D><G><E><I><G><D><A... | Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.<BOP> | P0A4J1 |
P35106 | LHB1_RHOPA | LH II-A beta | Rhodopseudomonas | <M><A><D><K><T><L><T><G><L><T><V><E><E><S><E><E><L><H><K><H><V><I><D><G><T><R><I><F><G><A><I><A><I><V><A><H><F><L><A><Y><V><Y><S><P><W><L><H> | Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.<BOP> | P35106 |
P94338 | PURNU_CORGL | S-methyl-5'-thioadenosine phosphorylase Cgl2154/cg2365 | Corynebacterium | <M><D><S><L><D><P><R><N><R><P><V><R><K><V><F><T><T><R><A><G><G><V><S><Q><S><P><Y><A><S><F><N><L><G><D><H><V><G><D><D><P><Q><A><V><A><S><N><R><N><R><L><A><D><I><I><G><L><S><P><D><K><V><V><Y><M><E><Q><I><H><S><N><T><V><T><V><I><D><E><A><P><A><D><G><Q><A><V><E><A><T><D><A><L><V><T><T><Q><R><G><L><A><L><A><V><L><V><A><D><C... | Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine. Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate. Also has ade... | P94338 |
A8M1K7 | CLPX_SALAI | ATP-dependent Clp protease ATP-binding subunit ClpX | Salinispora | <M><A><R><I><G><D><G><G><D><L><L><K><C><S><F><C><G><K><S><Q><K><Q><V><K><K><L><I><A><G><P><G><V><Y><I><C><D><E><C><I><D><L><C><N><E><I><I><E><E><E><L><A><E><S><G><E><V><K><W><E><E><L><P><K><P><M><E><I><C><Q><F><L><D><N><Y><V><V><G><Q><A><Q><A><K><K><A><L><A><V><A><V><Y><N><H><Y><K><R><I><Q><A><E><A><V><G><A><P><G><T><D... | ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.<BOP> | A8M1K7 |
G1UB63 | CSA1_CANAL | Wall protein 1 | Candida | <M><L><P><S><I><V><I><S><I><V><L><A><S><F><V><S><A><E><S><S><I><T><E><A><P><T><T><T><A><E><D><N><P><Y><T><I><Y><P><S><V><A><K><T><A><S><I><N><G><F><A><D><R><I><Y><D><Q><L><P><E><C><A><K><P><C><M><F><Q><N><T><G><V><T><P><C><P><Y><W><D><T><G><C><L><C><I><M><P><T><F><A><G><A><I><G><S><C><I><A><E><K><C><K><G><Q><D><V><V><S... | Heme-binding protein involved in heme-iron utilization. The ability to acquire iron from host tissues is a major virulence factor of pathogenic microorganisms. Required for biofilm formation.<BOP> | G1UB63 |
Q13283 | G3BP1_HUMAN | GAP SH3 domain-binding protein 1 | Homo | <M><V><M><E><K><P><S><P><L><L><V><G><R><E><F><V><R><Q><Y><Y><T><L><L><N><Q><A><P><D><M><L><H><R><F><Y><G><K><N><S><S><Y><V><H><G><G><L><D><S><N><G><K><P><A><D><A><V><Y><G><Q><K><E><I><H><R><K><V><M><S><Q><N><F><T><N><C><H><T><K><I><R><H><V><D><A><H><A><T><L><N><D><G><V><V><V><Q><V><M><G><L><L><S><N><N><N><Q><A><L><R><R... | ATP- and magnesium-dependent helicase that plays an essential role in innate immunity . Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also DDX58-induced type I interferon production probably by helping DDX58 at sensing pathogenic RNA . In addition, pl... | Q13283 |
Q7V483 | ENO_PROMM | 2-phosphoglycerate dehydratase | Prochlorococcus | <M><I><D><S><L><D><L><V><I><D><T><I><V><A><R><E><V><L><D><S><R><G><N><P><T><V><E><A><E><V><L><L><E><A><G><A><I><G><R><A><I><V><P><S><G><A><S><T><G><A><H><E><A><H><E><L><R><D><G><D><S><R><Y><L><G><K><G><V><T><K><A><V><N><H><I><E><D><R><I><A><P><A><L><C><G><I><S><S><L><D><Q><A><S><V><D><G><T><M><Q><E><L><D><G><S><D><N><K... | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP> | Q7V483 |
C5A0E6 | PHYDA_ECOBW | Hydantoin-utilizing enzyme HyuA | Escherichia | <M><R><V><L><I><K><N><G><T><V><V><N><A><D><G><Q><A><K><Q><D><L><L><I><E><S><G><I><V><R><Q><L><G><N><N><I><S><P><Q><L><P><Y><E><E><I><D><A><T><G><C><Y><V><F><P><G><G><V><D><V><H><T><H><F><N><I><D><V><G><I><A><R><S><C><D><D><F><F><T><G><T><R><A><A><A><C><G><G><T><T><T><I><I><D><H><M><G><F><G><P><N><G><C><R><L><R><H><Q><L... | Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin derivatives with an aromatic side chains at the 5'-position. Has no activity on dihydropyrimidines. The physiological function is unknown.<BOP> | C5A0E6 |
Q04UJ2 | KTHY_LEPBJ | dTMP kinase | Leptospira | <M><K><I><E><K><P><I><F><V><V><F><E><G><I><D><G><S><G><K><S><T><L><C><K><S><L><T><E><K><L><T><E><R><G><I><P><S><V><N><F><T><E><P><T><N><F><E><T><G><K><Y><L><R><K><F><L><R><G><E><I><D><L><E><R><K><E><Q><I><D><A><F><L><N><D><R><E><E><S><L><R><Q><N><I><L><P><S><L><E><S><G><K><N><V><L><L><D><R><Y><M><Y><S><T><A><A><Y><Q><S... | Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.<BOP> | Q04UJ2 |
Q8YRN1 | RNPA_NOSS1 | Protein C5 | Nostoc | <M><A><L><P><K><A><N><R><L><K><S><R><H><D><F><Q><A><V><F><R><E><G><L><R><R><N><S><S><H><F><T><L><R><A><L><K><P><S><S><A><R><K><S><S><L><D><T><A><A><Q><T><Q><P><V><D><E><V><Q><N><I><P><S><T><L><I><G><V><S><I><S><T><K><V><S><K><R><A><V><V><R><N><R><I><K><R><Q><I><T><A><A><M><Q><Q><L><L><P><R><L><A><P><G><W><K><L><V><V><I... | RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the riboz... | Q8YRN1 |
O94903 | PLPHP_HUMAN | Pyridoxal phosphate-binding protein | Homo | <M><W><R><A><G><S><M><S><A><E><L><G><V><G><C><A><L><R><A><V><N><E><R><V><Q><Q><A><V><A><R><R><P><R><D><L><P><A><I><Q><P><R><L><V><A><V><S><K><T><K><P><A><D><M><V><I><E><A><Y><G><H><G><Q><R><T><F><G><E><N><Y><V><Q><E><L><L><E><K><A><S><N><P><K><I><L><S><L><C><P><E><I><K><W><H><F><I><G><H><L><Q><K><Q><N><V><N><K><L><M><A... | Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.<BOP> | O94903 |
B6ITH3 | GLMM_RHOCS | Phosphoglucosamine mutase | Rhodospirillum | <M><T><R><R><L><F><G><T><D><G><I><R><G><T><A><N><T><D><P><M><T><A><E><M><A><L><K><V><A><M><A><T><A><A><Q><F><R><R><G><S><H><R><H><V><V><V><I><A><K><D><T><R><L><S><G><Y><M><L><E><P><A><L><T><A><G><F><V><S><M><G><M><D><V><V><L><V><G><P><L><P><T><P><A><V><A><M><L><T><R><S><L><R><A><D><L><G><V><M><V><S><A><S><H><N><P><F><H... | Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.<BOP> | B6ITH3 |
P38989 | SMC2_YEAST | DA-box protein SMC2 | Saccharomyces | <M><K><V><E><E><L><I><I><D><G><F><K><S><Y><A><T><R><T><V><I><T><D><W><D><P><Q><F><N><A><I><T><G><L><N><G><S><G><K><S><N><I><L><D><A><I><C><F><V><L><G><I><A><S><M><S><T><V><R><A><S><S><L><Q><D><L><I><Y><K><R><G><Q><A><G><V><T><K><A><S><V><T><I><V><F><D><N><T><D><K><S><N><S><P><I><G><F><T><N><S><P><Q><I><S><V><T><R><Q><V... | Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the... | P38989 |
Q2SNC4 | COBQ_HAHCH | Cobyric acid synthase | Hahella | <M><T><N><K><T><L><M><I><Q><G><T><T><S><D><A><G><K><S><T><L><V><T><A><I><C><R><S><L><L><R><R><G><V><K><V><A><P><F><K><P><Q><N><M><A><L><N><S><A><V><T><V><D><G><G><E><I><G><R><A><Q><A><V><Q><A><Q><A><C><G><L><Q><P><H><T><D><M><N><P><V><L><L><K><P><N><T><D><I><G><A><Q><V><I><I><H><G><K><A><R><A><N><M><D><A><V><A><Y><H><D... | Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.<BOP> | Q2SNC4 |
P39464 | GGPS_SULAC | Geranylgeranyl diphosphate synthase | Sulfolobus | <M><S><Y><F><D><N><Y><F><N><E><I><V><N><S><V><N><D><I><I><K><S><Y><I><S><G><D><V><P><K><L><Y><E><A><S><Y><H><L><F><T><S><G><G><K><R><L><R><P><L><I><L><T><I><S><S><D><L><F><G><G><Q><R><E><R><A><Y><Y><A><G><A><A><I><E><V><L><H><T><F><T><L><V><H><D><D><I><M><D><Q><D><N><I><R><R><G><L><P><T><V><H><V><K><Y><G><L><P><L><A><I... | Catalyzes the condensation of isopentenyl pyrophosphate with the allylic pyrophosphates to yield geranylgeranyl diphosphate (GGPP) which is a precursor of the ether-linked lipids. It is able to use dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), and (all-E)-geranyl diphosphate (E-FPP) as an allylic substr... | P39464 |
Q39JJ6 | SYY_BURL3 | Tyrosyl-tRNA synthetase | Burkholderia cepacia complex | <M><S><T><E><P><S><S><K><P><V><F><P><I><T><D><E><V><R><H><A><L><A><V><T><K><R><G><V><D><E><L><L><V><E><E><E><F><A><Q><K><L><A><R><S><A><A><T><G><T><P><L><R><I><K><L><G><L><D><P><T><A><P><D><I><H><I><G><H><T><V><V><L><N><K><M><R><Q><L><Q><D><L><G><H><T><V><I><F><L><I><G><D><F><T><S><L><I><G><D><P><S><G><R><N><A><T><R><P... | Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<BOP> | Q39JJ6 |
Q6BGW3 | CPD1_DEBHA | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | Debaryomyces | <M><T><L><M><S><S><L><N><T><L><F><P><G><Q><P><P><K><F><E><P><H><I><T><I><S><S><N><I><D><V><D><L><D><H><P><D><K><T><K><S><D><V><Y><R><I><L><S><A><S><L><V><A><I><D><S><L><P><K><N><H><S><N><L><V><T><L><G><K><V><D><S><Q><R><K><F><F><K><K><L><Y><F><Q><V><A><R><D><P><N><L><V><S><F><A><T><I><I><R><E><L><F><V><Q><L><P><A><D><I... | Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.<BOP> | Q6BGW3 |
P25830 | RBL_CERGL | Ribulose bisphosphate carboxylase large chain | Cerastium | <M><S><P><Q><T><E><T><K><S><S><V><G><F><K><A><G><V><K><D><Y><K><L><T><Y><Y><T><P><E><Y><E><T><L><D><T><D><I><L><A><A><F><R><V><T><P><Q><P><G><V><P><P><E><E><A><G><A><A><V><A><A><E><S><S><T><G><T><W><T><T><V><W><T><D><G><L><T><S><L><D><R><Y><K><G><R><C><Y><H><I><E><P><V><A><G><E><E><N><Q><Y><I><C><Y><V><A><Y><P><L><D><L... | RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.<BOP> | P25830 |
Q5K3T8 | PETL_BISOF | Cytochrome b6-f complex subunit VI | Bistorta | <M><L><T><L><T><S><Y><F><G><F><L><L><A><A><L><T><I><T><S><A><L><F><I><G><L><S><K><I><R><L><I> | Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex... | Q5K3T8 |
Q9WYC5 | PFP_THEMA | Pyrophosphate-dependent 6-phosphofructose-1-kinase | Thermotoga | <M><A><E><R><L><G><I><L><V><G><G><G><P><A><P><G><I><N><S><V><I><S><S><V><T><I><E><A><I><N><N><G><L><E><V><I><G><I><Y><D><G><F><K><H><L><V><E><G><K><T><N><M><V><K><K><L><S><I><E><D><V><S><R><I><H><I><E><G><G><S><I><L><R><T><S><R><V><N><P><A><K><S><E><E><T><L><E><K><T><V><Q><T><L><K><K><L><G><I><K><Y><L><V><T><I><G><G><D... | Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenes... | Q9WYC5 |
B1VQW8 | SYD_STRGG | Aspartyl-tRNA synthetase | Streptomyces | <M><H><R><Y><R><S><H><T><C><G><E><L><R><A><S><D><V><G><T><D><V><R><L><S><G><W><L><H><N><R><R><D><L><G><G><I><L><F><I><D><L><R><D><H><Y><G><L><V><Q><L><V><A><R><P><G><T><P><G><N><D><A><L><A><K><L><T><K><E><T><V><V><R><I><D><G><K><V><S><A><R><G><A><D><N><V><N><P><E><L><P><T><G><E><I><E><I><E><V><T><E><V><E><V><L><G><E><A... | Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).<BOP> | B1VQW8 |
A4W6K4 | ZAPD_ENT38 | Z ring-associated protein D | Enterobacter | <M><S><S><H><I><L><F><E><H><P><L><N><E><K><M><R><T><W><L><R><I><E><F><L><I><Q><Q><M><S><F><H><L><P><I><A><E><H><A><T><A><L><H><F><F><R><N><V><G><D><L><L><D><V><I><E><R><G><D><V><R><T><E><L><L><K><E><L><E><R><Q><Q><R><K><L><Q><G><W><A><E><V><P><G><V><D><Q><N><R><I><D><S><I><R><L><Q><L><K><Q><S><S><T><I><L><M><A><A><P><R... | Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.<BOP> | A4W6K4 |
C3MEY7 | NUOK2_SINFN | NDH-1 subunit K 2 | Sinorhizobium | <M><V><P><L><W><W><H><I><S><L><G><V><A><L><F><V><I><G><A><A><G><V><L><L><R><R><N><I><L><V><V><L><M><S><L><E><L><L><L><N><S><V><N><I><N><F><I><A><F><G><R><Y><Y><A><D><F><R><G><Q><I><F><A><I><F><V><I><A><I><T><A><A><E><V><A><V><A><L><G><I><L><V><A><L><V><R><N><K><S><T><L><K><V><D><D><V><T><V><M><K><G> | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t... | C3MEY7 |
Q9VH36 | CRBN_DROME | Protein ohgata | Sophophora | <M><D><E><E><E><N><S><E><I><N><S><V><Q><A><R><D><E><D><V><Q><L><E><D><Q><Q><S><Q><G><L><Q><D><R><Q><V><D><V><I><E><Q><A><W><N><N><A><M><P><D><E><P><S><P><P><A><E><D><A><F><Q><D><P><L><A><T><D><G><E><G><G><D><A><L><E><A><M><V><E><N><V><L><Q><D><D><T><A><S><E><G><S><H><P><S><S><D><M><S><L><E><S><P><G><S><E><D><D><S><D><L... | Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins (Probable). Has an essential role in mediating growth by negatively regulating insulin signaling . It also has a role in maintaining presynaptic... | Q9VH36 |
Q9YBF8 | SYG_AERPE | Glycyl-tRNA synthetase | Aeropyrum | <M><A><E><D><L><F><E><K><L><V><E><I><G><K><R><R><G><F><F><W><P><S><Y><E><I><Y><G><G><V><A><G><F><Y><D><W><G><P><L><G><H><L><L><K><R><R><I><I><E><K><W><R><R><Y><F><V><L><M><H><Q><D><H><V><V><E><I><E><T><P><V><I><G><P><E><K><V><Y><I><A><S><G><H><V><E><H><F><T><D><P><I><V><R><C><T><S><C><G><R><T><F><R><A><D><H><L><V><E><E... | Catalyzes the attachment of glycine to tRNA(Gly).<BOP> | Q9YBF8 |
Q8WZK0 | US107_SCHPO | U1 snRNP-associated protein usp107 | Schizosaccharomyces | <M><Q><R><Q><N><T><Q><A><A><G><M><P><M><M><P><Q><V><P><M><V><G><N><G><V><P><Y><V><V><P><I><Q><P><V><F><A><P><L><P><P><D><Y><R><S><L><Y><K><K><L><Y><G><Q><G><A><F><L><V><D><N><P><V><E><A><S><S><P><Y><D><F><S><Q><P><I><L><K><F><G><K><L><P><I><K><Q><V><L><R><D><N><E><S><Q><Q><K><D><R><K><N><L><P><R><N><Q><K><S><N><E><I><Q... | Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.<BOP> | Q8WZK0 |
B2FHZ0 | ATPA_STRMK | F-ATPase subunit alpha | Stenotrophomonas maltophilia group | <M><A><T><T><L><N><P><S><E><I><S><E><L><I><K><N><R><I><E><K><V><K><L><A><A><E><S><R><N><E><G><T><V><T><S><V><S><D><G><I><V><R><I><F><G><L><A><D><V><M><Q><G><E><M><I><E><L><P><N><N><T><F><A><L><A><L><N><L><E><R><D><S><V><G><A><V><V><L><G><D><Y><E><H><L><R><E><G><D><V><A><K><T><T><G><R><I><L><E><V><P><V><G><P><E><L><L><G... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.<BOP> | B2FHZ0 |
P58052 | IDI2_STAAU | Type 2 isopentenyl diphosphate isomerase | Staphylococcus | <M><S><D><F><Q><R><E><Q><R><K><N><E><H><V><E><I><A><M><A><Q><S><D><A><M><H><S><D><F><D><K><M><R><F><V><H><H><S><I><P><S><I><N><V><N><D><I><D><L><T><S><Q><T><P><D><L><T><M><T><Y><P><V><Y><I><N><A><M><T><G><G><S><E><W><T><K><N><I><N><E><K><L><A><V><V><A><R><E><T><G><L><A><M><A><V><G><S><T><H><A><A><L><R><N><P><R><M><A><E... | Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).<BOP> | P58052 |
P0DOV6 | SGL_PSEPU | 6-deoxy-6-sulfogluconolactone lactonase | Pseudomonas | <M><N><E><T><L><K><C><V><V><R><Q><P><S><V><L><G><E><C><P><V><W><S><V><R><E><Q><V><L><Y><W><A><D><I><L><A><G><R><L><H><R><L><D><P><R><D><G><S><V><S><T><L><Q><L><P><E><E><L><G><C><F><G><L><R><E><Q><G><G><F><I><V><A><L><R><S><G><I><Y><L><L><D><A><H><G><Q><L><G><E><R><L><A><E><N><P><T><G><A><E><H><S><R><F><N><D><G><R><V><D... | Catalyzes the hydrolysis of 6-deoxy-6-sulfo-D-glucono-1,5-lactone to form 6-deoxy-6-sulfo-D-gluconate. Is involved in a degradation pathway of sulfoquinovose (SQ) that allows P.putida SQ1 to use SQ as the sole carbon and energy source for growth.<BOP> | P0DOV6 |
O84492 | HEMH_CHLTR | Protoheme ferro-lyase | Chlamydia | <M><V><T><Y><L><L><A><N><F><G><G><P><R><T><S><Q><E><I><V><S><F><L><Q><A><L><L><T><D><R><D><V><T><G><G><M><I><P><S><M><L><H><R><P><L><F><S><Y><I><A><K><R><R><A><P><H><V><A><R><Q><Y><A><Y><L><G><G><G><S><P><I><F><Q><D><T><E><R><L><A><Q><N><L><S><Q><E><L><Q><A><S><V><I><P><F><H><R><Y><L><P><E><T><H><R><E><T><L><Q><A><L><Q... | Catalyzes the ferrous insertion into protoporphyrin IX.<BOP> | O84492 |
Q7RTT5 | SSX7_HUMAN | Protein SSX7 | Homo | <M><N><G><D><D><A><F><A><R><R><P><R><A><G><A><Q><I><P><E><K><I><Q><K><S><F><D><D><I><A><K><Y><F><S><K><K><E><W><E><K><M><K><S><L><E><K><I><S><Y><V><Y><M><K><R><K><Y><E><A><M><T><K><L><G><F><K><A><T><L><P><P><F><M><H><N><T><G><A><T><D><L><Q><G><N><D><F><D><N><D><R><N><Q><G><N><Q><V><E><R><P><Q><M><T><F><C><R><L><Q><R><I... | Could act as a modulator of transcription.<BOP> | Q7RTT5 |
Q39ED2 | ILVC_BURL3 | Ketol-acid reductoisomerase type I | Burkholderia cepacia complex | <M><N><V><F><Y><D><K><D><A><D><L><S><L><I><K><G><K><Q><V><T><I><I><G><Y><G><S><Q><G><H><A><H><A><L><N><L><K><D><S><G><V><N><V><T><V><G><L><R><K><G><G><A><S><W><S><K><A><E><N><A><G><L><S><V><K><E><V><A><E><A><V><K><S><A><D><V><V><M><M><L><L><P><D><E><Q><I><A><D><V><Y><A><K><E><V><H><A><N><I><K><Q><G><A><A><L><A><F><A><H... | Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobu... | Q39ED2 |
Q42800 | DAPA_SOYBN | 4-hydroxy-tetrahydrodipicolinate synthase, chloroplastic | Glycine subgen. Soja | <M><I><T><N><S><A><A><V><K><P><N><F><H><L><P><M><R><S><F><E><L><K><N><R><T><S><P><E><D><I><K><A><L><R><L><I><T><A><I><K><T><P><Y><L><P><D><G><R><F><D><L><E><A><Y><D><D><L><V><N><M><Q><I><G><Q><G><A><E><G><V><I><V><G><G><T><T><G><E><G><Q><L><M><S><W><E><E><H><I><I><L><I><A><H><T><V><N><C><F><G><G><K><I><K><V><I><G><N><T... | Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).<BOP> | Q42800 |
Q82XP5 | RUVC_NITEU | Holliday junction resolvase RuvC | Nitrosomonas | <M><T><S><L><V><Y><A><A><K><G><I><R><I><L><G><I><D><P><G><L><R><I><T><G><F><G><I><V><E><K><I><G><N><R><L><V><Y><I><G><S><G><C><V><V><T><G><E><S><G><L><P><D><R><L><K><T><I><L><D><G><L><N><E><I><I><L><Q><H><K><P><E><Q><V><A><V><E><Q><V><F><V><N><I><N><P><K><S><T><L><L><L><G><Q><A><R><G><A><A><I><S><A><A><V><L><H><E><L><S... | Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.<BOP> | Q82XP5 |
Q8K1A0 | METL5_MOUSE | Methyltransferase-like protein 5 | Mus | <M><K><K><L><K><L><K><E><L><E><S><R><L><Q><E><V><D><G><F><E><K><P><K><L><L><L><E><Q><Y><P><T><R><P><H><I><A><A><C><M><L><Y><T><I><H><N><T><Y><D><D><I><E><N><K><A><V><A><D><L><G><C><G><C><G><V><L><S><I><G><A><A><M><L><G><A><G><L><C><V><G><F><D><I><D><E><D><A><L><E><I><F><N><K><N><V><E><E><F><E><L><T><N><V><D><M><I><Q><C... | Catalytic subunit of a heterodimer with TRMT112, which specifically methylates the 6th position of adenine in position 1832 of 18S rRNA . N6-methylation of adenine(1832) in 18S rRNA resides in the decoding center of 18S rRNA and is required for translation and embryonic stem cells (ESCs) pluripotency and differentiatio... | Q8K1A0 |
Q2SVG9 | RBFA_BURTA | Ribosome-binding factor A | pseudomallei group | <M><S><K><K><R><S><S><P><N><R><N><V><Q><I><A><D><Q><I><Q><R><D><L><S><E><L><I><M><R><E><V><K><D><P><R><I><G><I><V><T><I><Q><S><V><E><L><T><P><D><Y><A><H><A><K><V><Y><F><T><A><L><T><G><N><P><A><D><T><Q><E><A><L><N><H><A><A><G><H><L><H><N><L><L><F><K><R><L><H><I><H><T><V><P><T><L><H><F><H><Y><D><Q><T><I><E><K><A><V><A><M... | One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal heli... | Q2SVG9 |
Q9KDV4 | GAL1_HALH5 | Galactose kinase | Halalkalibacterium (ex Joshi et al. 2022) | <M><E><V><A><Y><K><E><D><L><L><T><S><F><A><E><A><F><S><I><D><R><L><T><D><V><R><V><F><F><A><P><G><R><V><N><L><I><G><E><H><T><D><Y><N><G><G><Y><V><F><P><G><A><L><T><N><G><T><Y><M><V><I><K><L><R><D><D><G><E><Y><H><L><R><S><A><N><F><D><T><S><V><V><F><R><N><S><D><L><R><F><D><P><K><D><D><W><G><N><Y><P><K><G><I><I><A><E><L><A... | Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).<BOP> | Q9KDV4 |
Q4V8C9 | LRC56_RAT | Leucine-rich repeat-containing protein 56 | Rattus | <M><D><P><A><W><D><G><S><Q><G><S><R><P><G><T><A><S><I><R><V><R><E><L><S><W><Q><G><L><N><N><P><Q><P><Q><N><K><R><L><G><S><H><G><D><I><Y><R><E><R><R><V><E><E><H><L><S><P><A><R><L><Q><A><L><A><Q><V><D><D><L><Q><L><V><R><V><L><E><M><C><V><D><T><R><K><N><S><L><G><N><F><G><M><H><L><P><N><L><I><Q><L><K><L><N><H><S><C><L><G><S... | Required for the assembly of dynein arms.<BOP> | Q4V8C9 |
Q60B49 | LPXK_METCA | Lipid A 4'-kinase | Methylococcus | <M><S><R><S><N><G><V><I><D><A><W><L><Q><R><Q><W><Y><A><E><A><Q><P><P><W><G><L><R><A><L><S><R><G><F><G><A><A><V><A><L><R><R><G><Y><Y><R><R><N><A><K><V><S><L><G><V><P><V><I><V><V><G><N><L><S><V><G><G><T><G><K><T><P><L><V><I><A><L><V><E><L><L><R><Q><H><G><W><S><P><G><V><V><S><R><G><Y><R><G><S><A><R><A><P><L><E><V><F><C><G... | Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).<BOP> | Q60B49 |
B4TQC3 | FADI_SALSV | Fatty acid oxidation complex subunit beta | Salmonella | <M><R><Q><A><L><P><L><V><T><R><Q><G><D><R><I><A><I><V><S><G><L><R><T><P><F><A><R><Q><A><T><A><F><H><G><I><P><A><V><D><L><G><K><M><V><V><G><E><L><L><A><R><S><E><I><P><A><D><A><I><E><Q><L><V><F><G><Q><V><V><Q><M><P><E><A><P><N><I><A><R><E><I><V><L><G><T><G><M><N><V><H><T><D><A><Y><S><V><S><R><A><C><A><T><S><F><Q><A><V><A... | Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.<BOP> | B4TQC3 |
O00534 | VMA5A_HUMAN | Loss of heterozygosity 11 chromosomal region 2 gene A protein | Homo | <M><V><H><F><C><G><L><L><T><L><H><R><E><P><V><P><L><K><S><I><S><V><S><V><N><I><Y><E><F><V><A><G><V><S><A><T><L><N><Y><E><N><E><E><K><V><P><L><E><A><F><F><V><F><P><M><D><E><D><S><A><V><Y><S><F><E><A><L><V><D><G><K><K><I><V><A><E><L><Q><D><K><M><K><A><R><T><N><Y><E><K><A><I><S><Q><G><H><Q><A><F><L><L><E><G><D><S><S><S><R... | May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.<BOP> | O00534 |
I0DEB6 | NDB4T_MESSU | Non-disulfide-bridged peptide 5.12 | Mesomexovis | <M><K><T><Q><I><V><I><L><I><V><A><V><L><F><L><Q><L><V><S><Q><S><D><A><F><L><K><G><I><I><D><T><V><S><K><L><F><G><K><R><G><L><K><N><L><D><Q><Y><N><D><L><F><D><G><E><I><S><D><A><D><I><K><Y><L><Q><D><L><M><R> | Amphipathic peptide that shows no antibacterial activity even at 50 uM but shows a low hemolytic activity against human erythrocytes.<BOP> | I0DEB6 |
P48239 | GTO1_YEAST | Glutathione-dependent dehydroascorbate reductase | Saccharomyces | <M><S><V><S><Y><K><G><T><I><S><K><T><H><S><V><F><K><P><E><K><G><R><Y><Y><I><Y><G><A><L><G><C><P><F><T><H><R><A><I><L><A><R><S><L><K><K><L><E><P><V><L><G><L><V><L><S><H><W><Q><L><D><S><K><G><A><R><F><L><P><A><P><H><R><P><E><K><Y><K><E><R><F><F><T><A><T><G><G><I><A><S><A><K><L><D><E><S><E><E><L><G><D><V><N><N><D><S><A><R... | Active as '1-Cys' thiol transferase against beta-hydroxyethyl disulfide (HED), as dehydroascorbate reductase and as dimethylarsinic acid reductase, while not active against the standard GST substrate 1-chloro-2,4-dinitrobenzene (CDNB).<BOP> | P48239 |
A1JJQ6 | MTNN_YERE8 | S-adenosylhomocysteine nucleosidase | Yersinia | <M><K><V><G><I><I><G><A><M><E><E><E><V><T><L><L><R><D><K><I><E><N><R><Q><T><L><S><R><A><G><C><E><I><Y><T><G><Q><L><N><G><I><D><V><A><L><L><K><S><G><I><G><K><V><S><A><A><M><G><T><T><L><L><L><E><H><C><Q><P><D><I><V><I><N><T><G><S><A><G><G><L><A><S><S><L><K><V><G><D><I><V><V><S><T><E><V><R><Y><H><D><A><D><V><T><A><F><G><Y... | Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethio... | A1JJQ6 |
P59760 | GLYL_BOVIN | Glycolactin | Bos | <S><A><L><Y><A><L><Y><D><F><S><P><P><A><R><K><M><R><A><Y><T><V><R><A><Y><V><H><G><S><Y><S><R><R><G><P><W><Y><D><F><E><P><V><P><G><A><S><M><D><G><L> | Manifests poly C-specific RNase activity toward yeast tRNA, elicits a dose-dependent inhibition of cell-free translation, inhibits formation of superoxide ions in vitro and inhibits the hemagglutinating activities of soybean lectin and Ricinus communis agglutinin 120. Inhibits HIV-1 reverse transcriptase.<BOP> | P59760 |
C4Z111 | TRPD_LACE2 | Anthranilate phosphoribosyltransferase | Lachnospira | <M><I><K><E><A><I><A><K><L><V><K><K><E><D><L><T><A><G><Q><M><N><D><V><M><E><E><I><M><T><G><E><A><T><D><A><Q><K><A><A><F><L><T><A><L><A><A><K><G><E><T><I><D><E><I><T><A><A><A><R><V><L><R><A><H><C><E><K><F><L><N><D><M><D><V><L><E><I><V><G><T><G><G><D><G><S><N><S><I><N><I><S><T><L><A><S><I><I><V><S><A><A><G><I><P><V><A><K... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | C4Z111 |
Q3JRC7 | TIG_BURP1 | PPIase | pseudomallei group | <M><A><N><V><V><E><N><L><G><K><L><E><R><R><V><T><I><S><L><P><K><D><V><V><Q><K><E><I><D><A><R><I><Q><K><L><A><K><N><V><R><M><P><G><F><R><P><G><K><V><P><L><K><M><V><A><Q><Q><Y><A><G><Q><V><E><A><E><V><L><S><D><K><I><G><Q><E><F><F><T><I><S><R><A><E><N><L><R><V><A><G><Q><P><S><F><A><P><K><E><D><T><Q><Q><E><S><T><Y><A><F><D... | Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP> | Q3JRC7 |
A7MGA3 | RF3_CROS8 | Peptide chain release factor 3 | Cronobacter | <M><T><L><S><P><Y><L><Q><E><V><A><K><R><R><T><F><A><I><I><S><H><P><D><A><G><K><T><T><I><T><E><K><V><L><L><F><G><Q><A><I><Q><V><A><G><T><V><K><G><R><G><S><S><Q><H><A><K><S><D><W><M><E><M><E><K><Q><R><G><I><S><I><T><T><S><V><M><Q><F><P><Y><H><D><C><L><V><N><L><L><D><T><P><G><H><E><D><F><S><E><D><T><Y><R><T><L><T><A><V><D... | Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.<BOP> | A7MGA3 |
Q2ST43 | GLYA_MYCCT | Serine hydroxymethyltransferase | Mycoplasma | <M><N><T><K><I><N><S><K><I><R><E><S><L><N><K><E><L><K><R><Q><Q><S><H><I><E><L><I><A><S><E><N><Y><V><S><Q><A><V><L><E><L><N><G><S><V><L><T><N><K><Y><A><E><G><Y><P><G><K><R><Y><Y><G><G><C><E><F><I><D><E><I><E><S><L><G><I><Q><T><A><K><E><L><F><H><A><E><H><A><N><I><Q><P><H><S><G><S><Q><A><N><D><A><A><Y><K><A><L><L><E><P><K... | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a... | Q2ST43 |
Q9C691 | DEGP6_ARATH | Putative protease Do-like 6, chloroplastic | Arabidopsis | <M><L><F><R><S><V><H><H><I><V><A><R><F><S><N><S><T><S><T><P><I><H><R><F><F><Y><S><P><S><L><L><R><R><R><S><S><F><N><A><S><L><I><S><R><C><C><S><S><V><S><D><V><D><V><A><R><D><A><V><V><K><I><F><S><F><S><R><E><P><N><V><V><Q><P><W><Q><T><T><E><K><E><Y><S><S><S><G><F><A><I><S><G><R><R><I><L><T><N><A><H><V><V><G><D><H><L><Y><L... | Putative serine protease.<BOP> | Q9C691 |
Q11Z53 | DUT_CYTH3 | dUTP pyrophosphatase | Cytophaga | <M><K><R><C><L><N><K><A><N><M><T><T><S><V><K><I><V><N><K><S><N><N><A><L><P><A><Y><Q><T><A><Q><A><A><G><M><D><L><S><A><Y><I><T><E><A><I><V><L><Q><P><L><Q><R><Q><L><V><P><T><G><L><F><I><E><L><P><E><H><T><E><A><Q><I><R><P><R><S><G><L><A><F><K><H><G><I><T><V><L><N><S><P><G><T><I><D><A><D><Y><R><G><E><I><K><V><L><L><V><N><L... | This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.<BOP> | Q11Z53 |
A5PJD0 | URAD_BOVIN | Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase | Bos | <M><D><I><E><K><V><N><S><M><D><F><G><E><F><V><D><V><F><G><N><V><I><E><R><C><P><L><I><A><A><A><V><W><S><K><R><P><F><S><G><L><G><D><L><E><K><H><F><F><A><F><I><D><G><L><P><L><S><G><Q><E><G><V><L><R><C><H><P><E><L><A><G><R><Q><L><P><W><G><R><L><T><A><E><S><Q><R><E><Q><S><A><A><G><L><Q><N><L><G><A><A><E><R><L><R><F><T><E><L... | Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.<BOP> | A5PJD0 |
A5VAG4 | DAPF_RHIWR | PLP-independent amino acid racemase | Rhizorhabdus | <M><Q><V><R><F><H><K><M><H><G><L><G><N><D><F><V><V><I><D><A><R><A><T><A><P><V><E><M><T><A><A><R><A><R><A><L><A><D><R><K><T><G><V><G><C><D><Q><L><I><L><L><E><P><S><A><V><A><D><A><R><M><R><I><F><N><A><D><G><S><E><V><E><A><C><G><N><A><T><R><C><V><V><S><L><L><G><G><S><A><R><I><E><T><V><A><G><L><L><E><G><R><S><A><D><G><Q><V... | Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.<BOP> | A5VAG4 |
Q8GEK8 | Y264_METEX | 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase | Methylorubrum | <M><S><D><I><V><S><I><S><S><A><R><P><R><L><L><V><S><V><R><G><P><D><E><A><L><T><A><L><R><A><G><A><D><L><I><D><A><K><D><P><E><R><G><A><L><G><A><L><P><P><E><T><V><R><A><I><V><A><G><V><G><G><R><A><V><T><S><A><V><A><G><D><G><T><G><R><E><I><A><A><A><I><A><T><I><A><A><T><G><V><D><F><I><K><I><A><V><G><G><A><D><D><A><A><L><A><E... | Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).<BOP> | Q8GEK8 |
B9DS69 | RNH2_STRU0 | Ribonuclease HII | Streptococcus | <M><T><K><T><I><K><E><I><N><R><L><L><E><A><I><S><E><L><S><D><P><Y><F><I><E><L><E><S><D><D><R><V><G><V><K><K><A><V><N><K><R><R><K><A><I><Q><A><M><V><D><E><E><L><R><L><D><K><M><L><S><Y><E><K><V><L><Y><Q><E><G><F><S><L><I><A><G><I><D><E><V><G><R><G><P><L><A><G><P><V><V><A><A><C><V><I><L><P><I><D><C><K><I><K><G><L><N><D><S... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | B9DS69 |
Q9S3N1 | VIRB3_BARHE | Type IV secretion system protein virB3 | Bartonella | <M><N><E><D><P><L><F><L><A><C><T><R><P><A><M><F><A><G><V><T><M><E><A><M><A><F><N><V><M><A><T><S><I><L><F><I><L><T><S><G><F><T><M><I><G><L><G><I><G><L><H><F><V><L><R><E><I><T><K><H><D><H><N><Q><F><R><V><L><F><A><W><L><N><T><R><G><K><Q><K><N><L><N><R><W><G><G><G><S><T><S><P><L><R><L><I><R><T><Y><E><E><L><N><R> | The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function. VirB-dependent changes of HEC include massive cytoskeletal rearrangements, a pro-inflammatory activation by nuclear factor NF-kappa-B, inhibition of early and late events of apoptosis, leadi... | Q9S3N1 |
Q4CNH2 | ASNA_TRYCC | Arsenite-stimulated ATPase | Schizotrypanum | <M><S><L><E><P><T><L><R><D><L><L><H><S><K><L><Q><W><I><F><V><G><G><K><G><G><V><G><K><T><T><T><S><C><A><L><A><T><L><F><A><S><T><P><V><H><D><A><V><T><N><T><T><R><P><R><R><V><L><L><I><S><T><D><P><A><H><N><L><S><D><A><F><S><Q><K><F><G><K><T><P><V><P><V><N><G><M><E><E><T><L><F><A><M><E><V><D><P><T><T><F><T><H><G><G><F><G><A... | ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is... | Q4CNH2 |
B4XSY9 | SLAE_MACLB | C-type lectin A14 | Macrovipera | <M><G><R><F><I><F><V><R><V><G><L><L><V><V><F><L><S><L><S><G><T><G><A><D><F><D><C><P><P><D><W><S><A><Y><D><Q><H><C><Y><K><A><F><D><E><P><K><R><S><G><D><A><E><K><F><C><T><Q><Q><A><N><G><G><H><L><V><S><I><E><S><V><E><E><A><E><F><V><A><Q><L><I><S><E><N><I><K><T><S><A><D><Y><V><W><I><G><L><W><N><Q><R><K><A><P><Y><C><V><S><K... | Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).<BOP> | B4XSY9 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.