accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
Q7XR46
PAO4_ORYSJ
Polyamine oxidase 4
Oryza sativa
<M><D><P><N><S><L><K><T><G><G><L><L><L><P><T><I><E><R><Q><C><A><S><P><P><S><V><I><V><I><G><G><G><I><S><G><V><A><A><A><R><A><L><S><N><A><S><F><E><V><T><V><L><E><S><R><D><R><V><G><G><R><V><H><T><D><Y><S><F><G><C><P><I><D><M><G><A><S><W><L><H><G><V><C><N><E><N><S><L><A><P><L><I><G><Y><L><G><L><K><L><Y><R><T><S><G><D><N><S...
Flavoenzyme involved in polyamine back-conversion . Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine . Substrate preference is spermine > thermospermine > norspermine . No activity detected when putrescine, spermidine or N(1)-acetylspermidine are used as substrates . Plays an importa...
Q7XR46
Q65US7
THIE_MANSM
Thiamine-phosphate pyrophosphorylase
Basfia
<M><N><K><I><K><S><M><L><S><V><Y><F><I><A><G><S><Q><D><C><R><H><L><P><G><E><P><T><E><N><L><L><T><I><L><Q><R><A><L><E><A><G><I><T><C><F><Q><F><R><E><K><G><E><Q><S><L><A><C><D><L><Q><L><K><R><R><L><A><L><K><C><L><Q><L><C><R><Q><F><Q><V><P><F><I><V><N><D><D><V><E><L><A><L><S><I><Q><A><D><G><I><H><V><G><Q><K><D><T><A><V><E...
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP>
Q65US7
Q03EB7
RL4_PEDPA
50S ribosomal protein L4
Pediococcus
<M><A><N><V><S><L><F><K><Q><D><G><T><K><N><G><D><V><E><L><N><A><D><I><F><G><I><E><P><N><N><D><V><V><F><E><A><V><V><M><Q><R><A><S><M><R><Q><G><T><H><A><V><K><N><R><S><A><V><R><G><G><G><R><K><P><W><R><Q><K><G><T><G><R><A><R><Q><G><S><I><R><S><P><Q><W><R><G><G><G><I><V><F><G><P><T><P><R><S><Y><A><Y><S><I><P><K><K><M><R><R...
Forms part of the polypeptide exit tunnel.<BOP>
Q03EB7
Q8C042
ENO4_MOUSE
2-phospho-D-glycerate hydro-lyase
Mus
<M><G><D><E><D><G><G><R><R><G><G><I><T><R><D><L><Q><K><L><K><Q><Q><A><M><A><Y><Y><Q><E><N><D><V><P><R><K><L><E><D><L><L><N><S><T><F><Y><L><Q><P><A><D><V><Y><G><H><L><K><A><N><Y><F><S><K><L><A><K><P><P><S><I><C><K><I><V><G><K><T><I><L><D><G><L><G><L><P><T><L><Q><V><E><I><S><C><T><I><Q><N><F><P><K><Y><I><C><A><V><A><I><P...
Required for sperm motility, function and male fertility. May be involved in the normal assembly of the sperm fibrous sheath and provides most of the enolase activity in sperm .<BOP>
Q8C042
Q4JK59
TET2_MOUSE
Protein Ayu17-449
Mus
<M><E><Q><D><R><T><T><H><A><E><G><T><R><L><S><P><F><L><I><A><P><P><S><P><I><S><H><T><E><P><L><A><V><K><L><Q><N><G><S><P><L><A><E><R><P><H><P><E><V><N><G><D><T><K><W><Q><S><S><Q><S><C><Y><G><I><S><H><M><K><G><S><Q><S><S><H><E><S><P><H><E><D><R><G><Y><S><R><C><L><Q><N><G><G><I><K><R><T><V><S><E><P><S><L><S><G><L><H><P><N...
Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and con...
Q4JK59
Q5HQV2
TPIS_STAEQ
Triose-phosphate isomerase
Staphylococcus
<M><R><T><P><I><I><A><G><N><W><K><M><N><K><T><V><Q><E><A><K><D><F><V><N><E><L><P><T><L><P><D><P><K><E><V><E><S><V><I><C><A><P><T><I><Q><L><D><A><L><V><T><A><V><K><D><G><K><A><K><G><L><K><I><G><A><Q><N><A><Y><F><E><E><S><G><A><Y><T><G><E><T><S><P><V><A><L><S><E><L><G><V><K><Y><V><V><I><G><H><S><E><R><R><D><Y><F><H><E><T...
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP>
Q5HQV2
P49771
FLT3L_HUMAN
SL cytokine
Homo
<M><T><V><L><A><P><A><W><S><P><T><T><Y><L><L><L><L><L><L><L><S><S><G><L><S><G><T><Q><D><C><S><F><Q><H><S><P><I><S><S><D><F><A><V><K><I><R><E><L><S><D><Y><L><L><Q><D><Y><P><V><T><V><A><S><N><L><Q><D><E><E><L><C><G><G><L><W><R><L><V><L><A><Q><R><W><M><E><R><L><K><T><V><A><G><S><K><M><Q><G><L><L><E><R><V><N><T><E><I><H><F...
Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.<BOP>
P49771
O05949
DPO1_RICPR
DNA polymerase I
typhus group
<M><T><K><K><N><T><L><L><L><I><D><G><Y><G><F><V><F><R><A><Y><Y><A><Q><K><S><L><S><S><A><K><G><E><P><V><G><A><L><Y><G><F><T><S><M><L><L><K><L><L><S><D><F><K><P><Q><Y><V><A><I><V><F><D><S><G><G><K><N><F><R><H><K><I><Y><Q><N><Y><K><A><N><R><P><L><P><P><K><D><L><I><A><Q><L><P><L><V><R><D><V><A><S><N><F><K><F><A><I><L><E><K...
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.<BOP>
O05949
Q7TN16
HHIP_MOUSE
Hedgehog-interacting protein
Mus
<M><L><K><M><L><S><F><K><L><L><L><L><A><V><A><L><G><F><F><E><G><D><A><K><F><G><E><R><N><E><G><S><G><A><R><R><R><R><C><L><N><G><N><P><P><K><R><L><K><R><R><D><R><R><V><M><S><Q><L><E><L><L><S><G><G><E><I><L><C><G><G><F><Y><P><R><V><S><C><C><L><Q><S><D><S><P><G><L><G><R><L><E><N><K><I><F><S><A><T><N><N><S><E><C><S><R><L><L...
Modulates hedgehog signaling in several cell types, including brain and lung through direct interaction with members of the hedgehog family. Soluble forms inhibit Shh-induced differentiation in the fibroblast cell line C3H/10T1/2.<BOP>
Q7TN16
Q98QU6
ATPE_MYCPU
F-ATPase epsilon subunit
Mycoplasmopsis
<M><Q><L><Q><L><I><I><T><T><P><N><G><I><F><F><N><E><K><V><D><I><V><T><V><V><T><A><G><G><H><I><G><I><Q><Y><G><H><Q><P><L><I><S><T><I><E><I><S><E><L><H><I><N><T><E><G><H><K><D><Y><R><I><C><S><I><N><G><G><L><L><Y><V><E><K><D><K><A><N><I><I><T><G><A><I><E><F><K><E><D><I><D><I><E><K><A><R><R><E><H><D><Y><L><V><E><I><L><S><N...
Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP>
Q98QU6
B9UIY3
NDB45_LYCMC
Non-disulfide-bridged peptide 4.5
Lychas
<M><K><V><K><F><L><L><A><V><F><L><I><V><L><V><V><T><D><H><C><H><A><L><F><G><L><I><P><S><L><I><G><G><L><V><S><A><F><K><G><R><R><K><R><Q><M><E><A><R><F><E><P><Q><N><R><N><Y><R><K><R><E><L><D><L><E><K><L><F><A><N><M><P><D><Y>
Mutant mucroporin-M1: can inhibit Gram-positive bacteria at low concentrations and antibiotic-resistant pathogens. Minimum inhibitory concentrations (MIC) are the following: MIC=12.5 ug/ml against E.coli AB94012, MIC=100 ug/ml against P.aeruginosa AB93066, MIC=25 ug/ml against B.thuringiensis AB92037, MIC=25 ug/ml agai...
B9UIY3
C5JIC2
MTNB_BLAGS
Methylthioribulose-1-phosphate dehydratase
Blastomyces
<M><S><A><I><K><D><E><R><N><N><D><H><L><V><Q><S><H><D><P><E><H><P><A><N><L><I><P><A><L><C><R><N><F><Y><G><H><G><W><V><T><G><T><G><G><G><A><S><I><K><R><D><N><H><I><F><I><A><P><S><G><V><Q><K><E><L><I><Q><P><H><N><I><F><V><L><Q><Y><P><T><P><K><Y><P><P><S><A><R><Q><Y><I><R><K><P><L><E><L><K><P><S><A><C><T><P><L><F><L><A><A...
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).<BOP>
C5JIC2
Q9LYW5
LUL1_ARATH
RING finger protein 370
Arabidopsis
<M><G><N><L><I><S><L><I><F><C><C><G><R><R><Q><R><S><N><I><P><P><A><M><E><T><A><P><L><E><L><P><P><N><R><F><V><F><A><A><V><P><P><Y><L><N><P><N><P><N><Y><V><D><Q><Y><P><G><N><C><L><P><P><P><V><T><E><P><P><M><L><P><Y><N><F><N><H><L><H><H><Y><P><P><N><S><Y><Q><L><P><H><P><L><F><H><G><G><R><Y><P><I><L><P><P><P><T><Y><V><H><Q...
Acts as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates (in vitro).<BOP>
Q9LYW5
Q8NH02
O2T29_HUMAN
Olfactory receptor 2T29
Homo
<M><A><N><I><T><R><M><A><N><H><T><G><R><L><D><F><I><L><M><G><L><F><R><Q><S><K><H><P><A><L><L><S><V><V><I><F><V><V><F><L><K><A><L><S><G><N><A><V><L><I><L><L><I><H><C><D><A><H><L><H><S><P><M><Y><F><F><I><S><Q><L><S><L><M><D><M><A><Y><I><S><V><T><V><P><K><M><L><L><D><Q><V><M><G><V><N><K><V><S><A><P><E><C><G><M><Q><M><F><L...
Odorant receptor.<BOP>
Q8NH02
C1ESW4
RUVB_BACC3
Holliday junction ATP-dependent DNA helicase RuvB
Bacillus cereus group
<M><D><E><R><L><L><S><G><E><S><A><Y><E><D><A><D><L><E><Y><S><L><R><P><Q><T><L><R><Q><Y><I><G><Q><D><K><A><K><H><N><L><E><V><F><I><E><A><A><K><M><R><E><E><T><L><D><H><V><L><L><Y><G><P><P><G><L><G><K><T><T><L><A><N><I><I><A><N><E><M><G><V><N><V><R><T><T><S><G><P><A><I><E><R><P><G><D><L><A><A><V><L><T><S><L><Q><P><G><D><V...
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.<BOP>
C1ESW4
Q9YGC7
3S15_LATCO
Short neurotoxin NCA-02/NCA-05/UER-05
Laticauda
<M><K><T><L><L><L><T><L><V><V><V><T><M><V><C><L><D><L><G><Y><T><R><R><C><F><N><Q><Q><S><S><Q><P><K><T><T><K><S><C><P><L><G><E><N><S><C><Y><N><K><Q><W><R><D><H><R><G><S><I><T><E><R><G><C><G><C><P><K><V><K><P><G><I><K><L><R><C><C><E><S><E><D><C><N><N>
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.<BOP>
Q9YGC7
Q2KD50
FMT_RHIEC
Methionyl-tRNA formyltransferase
Rhizobium
<M><S><L><S><I><I><F><M><G><T><P><E><F><S><V><P><T><L><R><L><L><A><D><A><G><H><R><I><V><A><V><Y><T><Q><P><P><R><P><G><G><R><R><G><L><D><L><Q><K><S><P><V><H><Q><A><A><E><L><L><G><L><P><V><F><T><P><V><N><F><K><D><A><E><E><R><E><R><F><A><A><F><K><A><D><V><A><V><V><V><A><Y><G><L><L><L><P><E><A><V><L><N><G><T><R><D><G><C><Y...
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.<BOP>
Q2KD50
Q47MA5
HMUV_THEFY
Hemin import ATP-binding protein HmuV
Thermobifida
<M><K><R><I><R><Q><T><M><R><A><V><V><H><G><S><G><L><R><R><L><T><P><P><Q><R><V><T><S><G><T><V><V><L><G><A><R><H><L><S><K><S><Y><G><A><R><T><V><L><D><D><V><S><L><D><V><R><T><G><E><V><L><A><L><V><G><P><N><G><A><G><K><S><T><L><L><S><I><L><T><G><D><T><P><P><D><R><G><E><V><T><V><L><D><R><P><L><A><A><W><S><P><A><E><L><A><L><R...
Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system.<BOP>
Q47MA5
Q9BBS5
ATPI_LOTJA
F-ATPase subunit IV
Lotus
<M><N><V><L><L><C><S><I><N><T><F><K><R><L><Y><D><I><S><A><V><E><V><G><Q><H><F><Y><W><Q><M><G><D><F><Q><V><H><A><Q><V><L><I><T><S><W><V><V><I><A><I><L><L><G><S><T><I><L><V><V><R><N><P><Q><T><I><P><N><F><G><Q><N><F><F><E><Y><V><L><E><F><I><R><D><V><S><K><T><Q><I><G><E><E><Y><G><P><W><V><P><F><I><G><T><L><F><L><F><I><F><V...
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.<BOP>
Q9BBS5
Q9V4K2
GR43A_DROME
Gustatory receptor for sugar taste 43a
Sophophora
<M><E><I><S><Q><P><S><I><G><I><F><Y><I><S><K><V><L><A><L><A><P><Y><A><T><V><R><N><S><K><G><R><V><E><I><G><R><S><W><L><F><T><V><Y><S><A><T><L><T><V><V><M><V><F><L><T><Y><R><G><L><L><F><D><A><N><S><E><I><P><V><R><M><K><S><A><T><S><K><V><V><T><A><L><D><V><S><V><V><V><M><A><I><V><S><G><V><Y><C><G><L><F><S><L><N><D><T><L><E...
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates. Gr43a is the main sugar receptor in larvae. Functions as a narrowly tuned fructose receptor in taste neurons but also as a fructose receptor in the brain. Necessary and sufficient to sense hemolymph fructose and promote fee...
Q9V4K2
P33399
LHP1_YEAST
La ribonucleoprotein
Saccharomyces
<M><S><E><K><P><Q><Q><E><E><Q><E><K><P><Q><S><R><R><N><S><F><A><V><I><E><F><T><P><E><V><L><D><R><C><L><K><Q><V><E><F><Y><F><S><E><F><N><F><P><Y><D><R><F><L><R><T><T><A><E><K><N><D><G><W><V><P><I><S><T><I><A><T><F><N><R><M><K><K><Y><R><P><V><D><K><V><I><E><A><L><R><S><S><E><I><L><E><V><S><A><D><G><E><N><V><K><R><R><V><P...
Molecular chaperone that binds nascent RNA polymerase III transcripts, stabilizing these RNAs against exonucleases. Required for the 3' endonucleolytic cleavage that matures tRNA precursors and for efficient folding of certain pre-tRNAs. Cooperates with GCD14 in the maturation of a subset of RNA polymerase III transcri...
P33399
A4FVT7
RL15_METM5
50S ribosomal protein L15
Methanococcus
<M><I><R><K><S><K><K><I><T><K><M><R><G><S><R><T><C><G><Y><G><E><A><K><K><H><R><G><A><G><H><R><G><G><R><G><N><A><G><H><Q><K><H><K><W><L><S><V><C><K><F><N><P><D><Y><F><G><K><Y><G><F><N><R><N><P><C><L><I><K><Q><L><E><T><I><N><I><G><E><L><E><E><Y><I><L><K><Y><K><D><A><F><Q><V><E><D><G><K><V><V><V><D><A><T><T><I><G><Y><E><K...
Binds to the 23S rRNA.<BOP>
A4FVT7
Q9P121
NTRI_HUMAN
IgLON family member 2
Homo
<M><G><V><C><G><Y><L><F><L><P><W><K><C><L><V><V><V><S><L><R><L><L><F><L><V><P><T><G><V><P><V><R><S><G><D><A><T><F><P><K><A><M><D><N><V><T><V><R><Q><G><E><S><A><T><L><R><C><T><I><D><N><R><V><T><R><V><A><W><L><N><R><S><T><I><L><Y><A><G><N><D><K><W><C><L><D><P><R><V><V><L><L><S><N><T><Q><T><Q><Y><S><I><E><I><Q><N><V><D><V...
Neural cell adhesion molecule.<BOP>
Q9P121
A6V4G5
CLPS_PSEA7
ATP-dependent Clp protease adapter protein ClpS
Pseudomonas
<M><H><A><P><S><Q><I><R><L><T><F><N><Q><D><H><P><E><P><H><E><H><E><D><E><G><A><G><L><A><V><Q><E><S><K><P><V><L><Q><P><P><P><L><Y><K><V><V><L><F><N><D><D><Y><T><P><M><D><F><V><V><E><V><L><E><V><F><F><N><M><D><R><E><K><A><T><K><I><M><L><T><V><H><T><Q><G><K><A><V><C><G><L><F><T><R><D><V><A><E><T><K><A><M><Q><V><N><Q><Y><A...
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.<BOP>
A6V4G5
A0RBE8
PHNX_BACAH
Phosphonoacetaldehyde phosphonohydrolase
Bacillus cereus group
<M><K><I><E><A><V><I><F><D><W><A><G><T><T><V><D><Y><G><C><F><A><P><L><E><V><F><M><E><I><F><Y><K><R><G><V><G><I><T><A><E><E><A><R><K><P><M><G><L><L><K><I><D><H><V><R><A><L><T><E><M><P><R><I><A><N><E><W><N><R><I><F><G><Q><L><P><T><E><T><D><I><Q><E><M><Y><E><E><F><E><E><I><L><F><A><I><L><P><R><Y><A><S><P><I><H><G><V><K><E...
Involved in phosphonate degradation.<BOP>
A0RBE8
Q0IAF3
COAD_SYNS3
Pantetheine-phosphate adenylyltransferase
unclassified Synechococcus
<M><R><A><L><Y><P><G><S><F><D><P><L><T><L><G><H><L><D><L><I><E><R><G><C><S><L><F><G><E><V><V><V><A><V><L><Q><N><P><G><K><S><P><A><F><S><L><D><Q><R><L><E><Q><I><T><Q><A><T><S><H><L><Q><G><V><T><V><T><S><F><N><G><L><T><V><N><C><A><R><E><H><H><A><Q><L><I><L><R><G><L><R><A><M><S><D><F><E><Y><E><L><Q><I><A><H><T><N><R><S><L...
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP>
Q0IAF3
Q7SZ56
TM218_DANRE
Transmembrane protein 218
Danio
<M><A><D><V><V><L><G><V><G><T><G><V><F><I><I><T><L><I><W><I><L><T><L><A><L><T><I><I><L><S><R><A><T><G><P><T><K><L><G><I><I><P><V><V><L><L><A><L><I><I><T><L><V><L><V><F><F><P><R><A><A><E><V><P><A><P><Q><R><A><A><Q><I><V><D><M><F><F><I><G><R><Y><V><L><L><S><L><V><S><L><V><F><L><A><A><L><F><M><L><L><P><L><H><F><L><E><P><I...
May be involved in ciliary biogenesis or function.<BOP>
Q7SZ56
A1SL79
MURC_NOCSJ
UDP-N-acetylmuramoyl-L-alanine synthetase
Nocardioides
<M><R><L><P><V><P><D><Q><V><L><P><A><D><R><L><G><R><V><H><F><V><G><I><G><G><A><G><L><S><G><I><A><R><I><M><L><A><R><G><I><T><V><S><G><S><D><G><T><D><S><P><T><L><T><A><L><R><E><L><G><A><R><V><H><L><G><H><D><A><A><H><V><H><D><V><D><T><L><V><V><S><T><A><V><R><E><D><N><P><E><Y><V><E><A><V><R><Q><G><L><R><V><L><P><R><S><A><A...
Cell wall formation.<BOP>
A1SL79
Q5LDN0
RSMG_BACFN
16S rRNA 7-methylguanosine methyltransferase
Bacteroides
<M><K><L><L><L><K><Y><F><P><D><L><T><E><E><Q><R><K><Q><F><A><A><L><Y><E><L><Y><I><D><W><N><S><K><I><N><V><I><S><R><K><D><I><E><N><L><Y><E><H><H><V><L><H><S><L><G><I><A><R><I><I><R><F><R><A><G><S><S><V><M><D><L><G><T><G><G><G><F><P><G><I><P><L><A><I><L><F><P><D><T><K><F><H><L><V><D><S><I><G><K><K><V><R><V><A><T><E><V><A...
Specifically methylates the N7 position of a guanine in 16S rRNA.<BOP>
Q5LDN0
Q2S8Y5
ERPA_HAHCH
Iron-sulfur cluster insertion protein ErpA
Hahella
<M><N><V><A><E><T><Y><E><P><T><P><I><I><F><T><D><N><A><A><A><K><V><K><S><L><I><E><D><E><G><N><D><E><L><S><L><R><V><F><V><T><G><G><G><C><S><G><F><Q><Y><G><F><S><F><D><E><A><V><N><E><D><D><T><I><V><E><K><D><G><V><R><L><V><V><D><S><L><S><Y><Q><Y><L><V><G><A><E><V><D><F><R><E><G><L><E><G><A><Q><F><V><I><K><N><P><N><A><S><T...
Required for insertion of 4Fe-4S clusters for at least IspG.<BOP>
Q2S8Y5
P33535
OPRM_RAT
Opioid receptor B
Rattus
<M><D><S><S><T><G><P><G><N><T><S><D><C><S><D><P><L><A><Q><A><S><C><S><P><A><P><G><S><W><L><N><L><S><H><V><D><G><N><Q><S><D><P><C><G><L><N><R><T><G><L><G><G><N><D><S><L><C><P><Q><T><G><S><P><S><M><V><T><A><I><T><I><M><A><L><Y><S><I><V><C><V><V><G><L><F><G><N><F><L><V><M><Y><V><I><V><R><Y><T><K><M><K><T><A><T><N><I><Y><I...
Receptor for endogenous opioids such as beta-endorphin and endomorphin . Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone . Also activated by enkephalin peptides, such as Met-enkephalin or Met-enkephalin-Arg-Phe, with higher affinity for Met-e...
P33535
Q1LSJ4
RPIA_BAUCH
null
Candidatus Baumannia
<M><M><H><E><K><L><K><K><A><V><G><W><A><A><L><E><Y><V><S><S><G><M><I><I><G><V><G><T><G><S><T><T><D><H><F><I><D><A><L><G><T><V><K><H><K><I><E><G><V><V><S><S><S><E><Q><S><T><T><K><L><K><S><M><G><I><L><L><F><N><L><N><D><V><D><G><L><D><I><Y><V><D><G><T><D><E><I><N><S><N><M><Q><M><I><K><G><G><G><A><A><L><T><R><E><K><V><L><A...
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.<BOP>
Q1LSJ4
P09805
KTXA_KLULA
Endochitinase
Kluyveromyces
<M><N><I><F><Y><I><F><L><F><L><L><S><F><V><Q><G><L><E><H><T><H><R><R><G><S><L><V><K><R><A><V><C><Y><D><T><D><Q><V><P><L><N><I><F><F><G><Y><N><R><A><D><K><T><D><S><N><K><N><M><A><L><N><I><F><N><V><F><R><G><F><L><A><G><E><G><G><E><S><F><Y><N><S><N><G><N><V><Y><G><F><M><W><V><G><S><M><V><H><N><R><G><F><K><D><N><I><L><P><I...
The alpha subunit is a potent exochitinase. Along with the beta subunit it plays a role in the initial interaction of the toxin with sensitive cells and allow the gamma subunit (the active toxin) to gain entry into the cell.<BOP>
P09805
B0S2B6
RF1_FINM2
Peptide chain release factor 1
Finegoldia
<M><F><E><N><L><D><S><V><V><D><K><F><K><D><L><E><V><K><V><A><D><P><E><V><I><A><D><M><E><N><W><T><K><L><M><K><E><H><A><D><L><E><P><V><V><N><K><Y><L><S><Y><K><D><N><L><K><N><L><E><E><D><K><E><L><L><G><T><T><G><D><S><E><M><E><E><L><L><K><D><E><I><S><T><L><E><E><Q><I><E><K><D><Q><E><E><L><K><I><L><L><L><P><K><D><P><N><D><E...
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.<BOP>
B0S2B6
Q8XHA7
PROA_CLOPE
Glutamyl-gamma-semialdehyde dehydrogenase
Clostridium
<M><N><N><E><L><I><I><K><G><K><K><A><K><E><A><S><Y><T><L><S><F><A><S><T><N><E><K><D><N><G><L><L><K><I><S><E><F><L><I><K><R><C><D><E><I><L><E><E><N><K><K><D><L><E><K><A><I><E><K><G><T><S><N><A><M><L><D><R><L><K><L><D><E><E><R><V><K><S><I><A><N><A><V><A><D><V><V><K><L><D><D><P><I><G><E><V><T><S><M><F><K><R><P><N><G><L><R...
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.<BOP>
Q8XHA7
B8H3S9
DHMA_CAUVN
Haloalkane dehalogenase
Caulobacter
<M><D><V><L><R><T><P><D><E><R><F><E><G><L><A><D><W><S><F><A><P><H><Y><T><E><V><T><D><A><D><G><T><A><L><R><I><H><H><V><D><E><G><P><K><D><Q><R><P><I><L><L><M><H><G><E><P><S><W><A><Y><L><Y><R><K><V><I><A><E><L><V><A><K><G><H><R><V><V><A><P><D><L><V><G><F><G><R><S><D><K><P><A><K><R><T><D><Y><T><Y><E><R><H><V><A><W><M><S><A...
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.<BOP>
B8H3S9
A5VIC6
KTHY_LIMRD
dTMP kinase
Limosilactobacillus
<M><D><G><K><F><I><S><F><E><G><P><D><G><A><G><K><T><S><V><I><Q><Q><I><Q><L><E><L><E><D><Q><L><G><T><E><K><V><M><Y><T><R><E><P><G><G><N><K><I><S><E><Q><I><R><Q><V><L><F><D><G><Q><N><T><D><M><D><G><R><T><E><A><L><L><F><A><A><A><R><R><Q><H><I><V><S><E><I><I><P><G><L><K><A><G><K><V><I><L><C><D><R><F><V><D><S><S><I><A><Y><Q...
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.<BOP>
A5VIC6
A2BPY8
PURA_PROMS
IMP--aspartate ligase
Prochlorococcus
<M><A><N><V><V><V><I><G><A><Q><W><G><D><E><G><K><G><K><I><T><D><L><L><S><R><S><A><D><V><V><V><R><Y><Q><G><G><V><N><A><G><H><T><I><V><V><D><D><K><V><L><K><L><H><L><I><P><S><G><I><L><Y><K><N><T><S><C><L><I><G><S><G><T><V><I><D><P><K><I><L><L><K><E><I><D><M><L><I><D><N><G><I><D><I><S><G><L><K><I><S><S><T><S><H><V><T><M><P...
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.<BOP>
A2BPY8
Q47IZ9
CH10_DECAR
Chaperonin-10
Dechloromonas
<M><N><I><R><P><L><H><D><R><V><I><V><K><R><V><E><A><E><R><T><T><A><S><G><I><V><I><P><D><S><A><G><E><K><P><D><Q><G><E><V><L><A><V><G><P><G><K><R><D><D><N><G><K><Q><I><A><L><D><V><K><V><G><D><R><V><L><F><G><K><Y><A><G><Q><A><V><K><V><D><G><Q><E><V><L><V><M><R><E><E><D><I><M><G><V><L><V><A>
Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of ...
Q47IZ9
Q9XX85
ST217_CAEEL
G-protein coupled receptor str-217
Caenorhabditis
<M><L><L><F><Q><K><T><L><S><R><V><A><A><P><I><S><V><A><A><N><L><I><L><I><L><L><I><I><F><K><S><P><A><Q><M><G><N><Y><K><Y><L><L><I><G><L><S><I><F><E><M><S><Y><A><V><L><D><V><V><S><E><T><T><V><L><S><I><K><K><S><F><V><V><V><V><P><Y><K><D><R><S><F><G><Q><E><T><A><M><D><I><N><L><I><Y><C><G><F><F><G><F><S><M><G><M><F><V><V><I...
Probable G-protein coupled receptor.<BOP>
Q9XX85
A1K5Y4
PLSX_AZOSB
Phosphate-acyl-ACP acyltransferase
Azoarcus
<M><S><V><T><V><A><V><D><C><M><G><G><D><H><G><P><V><V><T><V><P><A><V><F><A><F><L><R><S><H><A><D><A><R><A><I><A><V><G><R><E><E><V><L><A><P><L><I><A><P><V><A><K><E><F><G><E><R><L><R><L><Q><P><A><T><E><V><V><G><M><D><E><A><P><A><T><A><M><R><N><K><K><D><S><S><M><R><V><A><I><D><L><V><K><S><G><E><A><T><A><A><V><S><A><G><N><T...
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.<BOP>
A1K5Y4
Q31886
RBL_BOUTR
Ribulose bisphosphate carboxylase large chain
Bouvardia
<M><S><P><Q><T><E><T><K><A><S><V><G><F><K><A><G><V><K><E><Y><K><L><T><Y><Y><T><P><E><Y><E><T><K><D><T><D><I><L><A><A><F><R><V><T><P><Q><P><G><V><P><P><E><E><A><G><A><A><V><A><A><E><S><S><T><G><T><W><T><T><V><W><T><D><G><L><T><S><L><D><R><Y><K><G><R><C><Y><H><I><E><P><V><P><G><E><E><D><Q><F><I><A><Y><V><A><Y><P><L><D><L...
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.<BOP>
Q31886
P55001
MFAP2_HUMAN
Microfibril-associated glycoprotein 1
Homo
<M><R><A><A><Y><L><F><L><L><F><L><P><A><G><L><L><A><Q><G><Q><Y><D><L><D><P><L><P><P><F><P><D><H><V><Q><Y><T><H><Y><S><D><Q><I><D><N><P><D><Y><Y><D><Y><Q><E><V><T><P><R><P><S><E><E><Q><F><Q><F><Q><S><Q><Q><Q><V><Q><Q><E><V><I><P><A><P><T><P><E><P><G><N><A><E><L><E><P><T><E><P><G><P><L><D><C><R><E><E><Q><Y><P><C><T><R><L...
Component of the elastin-associated microfibrils.<BOP>
P55001
P15455
CRU1_ARATH
12S seed storage protein CRA1 basic chain
Arabidopsis
<M><A><R><V><S><S><L><L><S><F><C><L><T><L><L><I><L><F><H><G><Y><A><A><Q><Q><G><Q><Q><G><Q><Q><F><P><N><E><C><Q><L><D><Q><L><N><A><L><E><P><S><H><V><L><K><S><E><A><G><R><I><E><V><W><D><H><H><A><P><Q><L><R><C><S><G><V><S><F><A><R><Y><I><I><E><S><K><G><L><Y><L><P><S><F><F><N><T><A><K><L><S><F><V><A><K><G><R><G><L><M><G><K...
Seed storage protein.<BOP>
P15455
Q67N08
AROC_SYMTH
5-enolpyruvylshikimate-3-phosphate phospholyase
Symbiobacterium
<M><R><Y><L><T><A><G><E><S><H><G><R><A><L><V><T><I><V><E><G><L><P><A><G><V><P><V><D><L><A><A><I><D><R><D><L><A><R><R><Q><S><G><Y><G><R><G><G><R><M><K><I><E><Q><D><R><V><Q><V><L><S><G><I><R><H><G><K><T><L><G><S><P><V><A><L><L><V><E><N><R><D><W><L><N><W><T><E><V><M><S><P><A><P><L><E><A><Y><T><D><P><R><A><A><Q><K><V><R><T...
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a s...
Q67N08
Q6YGZ1
HPSE_MOUSE
Heparanase 50 kDa subunit
Mus
<M><L><R><L><L><L><L><W><L><W><G><P><L><G><A><L><A><Q><G><A><P><A><G><T><A><P><T><D><D><V><V><D><L><E><F><Y><T><K><R><P><L><R><S><V><S><P><S><F><L><S><I><T><I><D><A><S><L><A><T><D><P><R><F><L><T><F><L><G><S><P><R><L><R><A><L><A><R><G><L><S><P><A><Y><L><R><F><G><G><T><K><T><D><F><L><I><F><D><P><D><K><E><P><T><S><E><E><R...
Endoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N-sulfo glucosamine unit carrying either a 3-O-sulfo or...
Q6YGZ1
Q5ZXP6
RIMO_LEGPH
Ribosome maturation factor RimO
Legionella
<M><N><H><K><V><G><F><V><S><L><G><C><P><K><A><L><V><D><S><E><R><I><I><T><Q><L><K><A><Q><G><Y><E><L><V><P><T><Y><Q><D><A><G><V><V><V><I><N><T><C><G><F><I><D><S><A><V><Q><E><S><L><D><T><I><K><E><A><M><A><E><N><G><R><V><I><V><T><G><C><L><G><A><K><A><D><V><I><K><N><A><C><P><D><V><L><H><I><S><G><A><H><A><Y><E><E><V><V><N><A...
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.<BOP>
Q5ZXP6
B3QP81
KTHY_CHLP8
dTMP kinase
Chlorobaculum
<M><L><I><T><F><E><G><I><D><G><A><G><K><S><T><Q><V><V><K><L><K><R><H><L><Q><E><R><G><R><E><V><L><T><L><R><E><P><G><G><T><P><V><A><E><Q><I><R><E><L><L><L><E><S><H><N><D><I><T><S><I><A><E><L><L><L><F><S><A><S><R><A><E><L><M><E><K><I><I><V><P><A><L><E><D><G><C><D><V><I><L><D><R><F><F><D><S><T><T><A><Y><Q><G><Y><G><R><G><L...
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.<BOP>
B3QP81
C1B381
RECA_RHOOB
Recombinase A
Rhodococcus
<M><A><P><Q><A><H><D><R><D><K><A><L><D><L><A><L><A><Q><I><D><K><N><F><G><K><G><S><V><M><R><L><G><E><G><V><R><Q><P><I><A><V><I><P><T><G><S><I><S><L><D><V><A><L><G><I><G><G><L><P><R><G><R><V><V><E><I><Y><G><P><E><S><S><G><K><T><T><V><A><L><H><A><V><A><N><A><Q><A><A><G><G><I><A><A><F><I><D><A><E><H><A><L><D><P><D><Y><A><Q...
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP>
C1B381
A7Z0J4
HSLO_BACVZ
Heat shock protein 33 homolog
Bacillus amyloliquefaciens group
<M><D><Y><L><I><K><A><I><A><Y><D><G><K><V><R><A><Y><A><A><R><T><T><D><M><V><N><E><A><Q><R><R><H><D><T><W><P><T><A><S><A><A><I><G><R><T><M><T><A><S><L><M><L><G><A><M><L><K><G><E><D><K><L><T><V><K><I><E><G><G><G><P><I><G><A><I><V><A><D><A><N><A><K><G><E><V><R><A><Y><V><S><N><P><H><V><H><F><D><L><N><E><Q><G><K><L><D><V><R...
Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.<BOP>
A7Z0J4
Q03I69
RLMH_STRTD
rRNA (pseudouridine-N3-)-methyltransferase RlmH
Streptococcus
<M><K><V><K><L><I><T><V><G><K><L><K><E><K><Y><L><K><D><G><I><A><E><Y><I><K><R><L><G><R><F><T><K><F><E><S><I><E><L><T><D><E><K><T><P><D><N><A><S><E><S><E><N><K><A><I><L><D><K><E><G><Q><R><I><L><A><K><V><G><D><R><D><Y><V><I><A><L><A><I><E><G><K><Q><F><P><S><E><Q><F><A><K><E><L><E><Q><A><T><L><R><G><Y><S><D><I><T><F><I><I...
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.<BOP>
Q03I69
A8FST3
SURE_SHESH
Nucleoside 5'-monophosphate phosphohydrolase
Shewanella
<M><I><K><I><L><V><S><N><D><D><G><V><T><A><P><G><I><K><A><L><S><D><A><L><S><T><S><Y><Q><V><M><T><V><G><P><D><R><N><C><S><G><A><S><N><S><L><T><L><T><N><P><L><R><I><N><T><L><S><N><G><Y><V><S><V><S><G><T><P><T><D><C><V><H><L><A><I><R><E><L><Y><T><D><E><P><D><M><V><V><S><G><I><N><A><G><A><N><L><G><D><D><T><L><Y><S><G><T><V...
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.<BOP>
A8FST3
B2UQY9
EFTU_AKKM8
Elongation factor Tu
Akkermansia
<M><A><K><E><Q><F><Q><R><N><K><P><H><V><N><V><G><T><I><G><H><V><D><H><G><K><T><S><L><T><A><A><I><T><S><V><L><A><K><K><G><F><A><E><A><R><G><Y><D><Q><I><D><A><A><P><E><E><R><E><R><G><I><T><I><S><T><A><H><V><E><Y><E><T><E><N><R><H><Y><A><H><V><D><C><P><G><H><A><D><Y><V><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V><V><A...
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP>
B2UQY9
B8CH91
FADB_SHEPW
3-hydroxyacyl-CoA dehydrogenase
Shewanella
<M><I><Y><Q><S><P><T><I><E><V><E><L><L><E><D><N><I><A><H><L><C><F><N><A><Q><G><S><V><N><K><F><D><R><E><T><I><D><S><L><N><A><A><L><D><S><I><K><Q><N><N><S><I><K><G><L><M><L><T><S><A><K><P><A><F><I><V><G><A><D><I><T><E><F><L><G><L><F><A><E><E><D><A><V><L><L><S><W><L><E><E><A><N><V><V><F><N><K><L><E><D><L><P><F><P><T><I><S...
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.<BOP>
B8CH91
P47407
RL14_MYCGE
50S ribosomal protein L14
Mycoplasma
<M><V><S><F><M><T><R><L><N><V><A><D><N><T><G><A><K><Q><V><G><I><I><K><V><L><G><A><T><Y><K><R><Y><A><F><L><G><D><V><V><V><V><S><V><K><D><A><I><P><N><G><M><V><K><K><G><Q><V><L><R><A><V><I><V><R><T><K><K><G><Q><Q><R><Q><D><G><T><H><L><K><F><H><D><N><A><C><V><L><I><K><E><D><K><S><P><R><G><T><R><I><F><G><P><V><A><R><E><L><R...
Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.<BOP>
P47407
Q8GVC7
PKZ1_PHYIN
Cleavage-associated kinase
Phytophthora
<M><L><R><L><G><R><S><A><A><S><E><V><S><S><I><R><N><S><L><Q><L><Q><L><E><Q><R><G><A><R><P><M><Q><C><A><Y><Q><T><Q><S><H><S><N><P><E><G><A><K><R><G><R><S><P><M><S><L><A><V><M><G><A><A><A><L><S><V><G><L><E><L><Q><T><D><G><I><A><Q><A><R><A><A><M><E><P><G><T><Q><L><Q><R><H><K><W><Q><L><F><D><Q><I><G><A><G><A><F><G><V><V><R...
May regulate an early stage of the zoospore pathway.<BOP>
Q8GVC7
A7FNI2
RPOC_YERP3
Transcriptase subunit beta'
Yersinia
<M><K><D><L><L><K><F><L><K><A><Q><T><K><T><E><E><F><D><A><I><K><I><A><L><A><S><P><D><M><I><R><S><W><S><F><G><E><V><K><K><P><E><T><I><N><Y><R><T><F><K><P><E><R><D><G><L><F><C><A><R><I><F><G><P><V><K><D><Y><E><C><L><C><G><K><Y><K><R><L><K><H><R><G><V><I><C><E><K><C><G><V><E><V><T><Q><T><K><V><R><R><E><R><M><G><H><I><E><L...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
A7FNI2
Q05196
PABP5_ARATH
Polyadenylate-binding protein 5
Arabidopsis
<M><A><A><A><V><A><S><G><I><A><P><T><T><A><M><V><D><Q><V><I><P><N><Q><P><T><V><A><A><A><A><P><P><P><F><P><A><V><S><Q><V><A><A><V><A><A><A><A><A><A><A><E><A><L><Q><T><H><P><N><S><S><L><Y><V><G><D><L><D><P><S><V><N><E><S><H><L><L><D><L><F><N><Q><V><A><P><V><H><N><L><R><V><C><R><D><L><T><H><R><S><L><G><Y><A><Y><V><N><F><A...
Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation.<BOP>
Q05196
Q86YC2
PALB2_HUMAN
Partner and localizer of BRCA2
Homo
<M><D><E><P><P><G><K><P><L><S><C><E><E><K><E><K><L><K><E><K><L><A><F><L><K><R><E><Y><S><K><T><L><A><R><L><Q><R><A><Q><R><A><E><K><I><K><H><S><I><K><K><T><V><E><E><Q><D><C><L><S><Q><Q><D><L><S><P><Q><L><K><H><S><E><P><K><N><K><I><C><V><Y><D><K><L><H><I><K><T><H><L><D><E><E><T><G><E><K><T><S><I><T><L><D><V><G><P><E><S><F...
Plays a critical role in homologous recombination repair (HRR) through its ability to recruit BRCA2 and RAD51 to DNA breaks . Strongly stimulates the DNA strand-invasion activity of RAD51, stabilizes the nucleoprotein filament against a disruptive BRC3-BRC4 polypeptide and helps RAD51 to overcome the suppressive effect...
Q86YC2
Q5U901
CBPA6_MOUSE
Carboxypeptidase A6
Mus
<M><N><F><L><G><N><P><R><S><H><T><A><A><F><L><P><V><C><W><L><L><L><N><I><L><K><P><G><H><C><H><S><Y><D><N><R><Y><A><G><D><K><V><I><R><L><I><P><K><S><E><E><E><A><L><A><L><K><N><I><Y><H><Q><L><K><V><D><L><W><Q><P><S><S><I><S><Y><V><S><E><G><T><I><T><D><V><H><I><S><Q><N><A><S><R><T><L><L><A><F><L><Q><E><T><H><I><Y><Y><K><V...
May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward smal...
Q5U901
A0A140JWT3
PTMC_PENSI
Penitrem biosynthesis cluster 1 protein C
Penicillium
<M><T><T><M><L><T><T><P><L><S><G><W><S><Q><L><S><L><S><F><L><T><L><T><V><G><A><L><A><L><I><V><V><L><Y><I><S><I><D><R><F><P><A><P><R><W><L><S><K><K><Y><Q><L><I><G><Q><K><D><P><A><S><T><T><S><L><E><C><P><Y><S><Y><I><R><Q><I><Y><G><H><Y><H><W><A><P><F><V><H><K><L><S><P><T><L><Q><Y><D><D><P><A><K><Y><K><M><V><L><E><I><M><D...
Prenyl transferase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes penitrems . The geranylgeranyl diphosphate (GGPP) synthase ptmG catalyzes the first step in penitrem biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (G...
A0A140JWT3
Q4QK37
IF2_HAEI8
Translation initiation factor IF-2
Haemophilus
<M><T><E><D><V><K><A><D><A><P><K><K><L><S><I><Q><R><R><T><K><T><T><V><S><S><T><T><T><G><G><K><S><K><E><V><Q><V><E><V><R><K><K><R><T><V><K><T><D><I><A><Q><Q><E><E><A><K><L><K><A><Q><Q><E><A><E><A><K><K><I><A><E><Q><K><A><A><E><E><K><A><R><L><E><A><E><K><A><A><T><K><K><E><A><D><E><K><S><K><A><E><K><A><K><A><E><T><A><K><P...
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.<BOP>
Q4QK37
P43176
BEV1C_BETPN
Allergen Bet v I-C
Betula
<M><G><V><F><N><Y><E><S><E><T><T><S><V><I><P><A><A><R><L><F><K><A><F><I><L><E><G><D><T><L><I><P><K><V><A><P><Q><A><I><S><S><V><E><N><I><E><G><N><G><G><P><G><T><I><K><K><I><T><F><P><E><G><S><P><F><K><Y><V><K><E><R><V><D><E><V><D><H><A><N><F><K><Y><S><Y><S><M><I><E><G><G><A><L><G><D><T><L><E><K><I><C><N><E><I><K><I><V><A...
May be a general steroid carrier protein.<BOP>
P43176
Q32NH9
FXJ12_XENLA
Forkhead box protein J1.2
Xenopus
<M><P><V><L><S><T><T><H><R><L><P><L><S><V><E><R><E><R><N><R><E><D><D><S><L><T><N><L><Q><W><L><Q><D><F><S><I><L><S><T><D><L><S><S><I><A><N><S><R><P><P><V><P><R><V><S><Q><G><P><C><S><P><P><A><G><D><T><A><S><C><Q><A><P><R><T><G><K><Q><R><V><T><V><P><T><A><W><A><S><L><P><T><L><S><P><S><P><V><Q><E><V><D><Y><R><T><N><A><N><V...
Key transcription factor required for motile ciliogenesis. Activates genes essential for motile cilia formation and function.<BOP>
Q32NH9
Q10716
CYSP1_MAIZE
Cysteine proteinase 1
Zea
<M><A><H><R><V><L><L><L><L><S><L><A><S><A><A><A><V><A><A><A><V><D><A><E><D><P><L><I><R><Q><V><V><P><G><G><D><D><N><D><L><E><L><N><A><E><S><H><F><L><S><F><V><Q><R><F><G><K><S><Y><K><D><A><D><E><H><A><Y><R><L><S><V><F><K><D><N><L><R><R><A><R><R><H><Q><L><L><D><P><S><A><E><H><G><V><T><K><F><S><D><L><T><P><A><E><F><R><R><T...
Involved in the degradation of the storage protein zein. May play a role in proteolysis during emergencies.<BOP>
Q10716
Q329K8
KGUA_SHIDS
GMP kinase
Shigella
<M><A><Q><G><T><L><Y><I><V><S><A><P><S><G><A><G><K><S><S><L><I><Q><A><L><L><K><T><Q><P><L><Y><D><T><Q><V><S><V><S><H><T><T><R><Q><P><R><P><G><E><V><H><G><E><H><Y><F><F><V><N><H><D><E><F><K><E><M><I><S><R><D><A><F><L><E><H><A><E><V><F><D><N><Y><Y><G><T><S><R><E><A><I><E><Q><V><L><A><T><G><V><D><V><F><L><D><I><D><W><Q><G...
Essential for recycling GMP and indirectly, cGMP.<BOP>
Q329K8
P49723
RIR4_YEAST
Ribonucleotide reductase small subunit 2
Saccharomyces
<M><E><A><H><N><Q><F><L><K><T><F><Q><K><E><R><H><D><M><K><E><A><E><K><D><E><I><L><L><M><E><N><S><R><R><F><V><M><F><P><I><K><Y><H><E><I><W><A><A><Y><K><K><V><E><A><S><F><W><T><A><E><E><I><E><L><A><K><D><T><E><D><F><Q><K><L><T><D><D><Q><K><T><Y><I><G><N><L><L><A><L><S><I><S><S><D><N><L><V><N><K><Y><L><I><E><N><F><S><A><Q...
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. RNR4 is required for proper folding of RNR2 and assembly with the large subunits.<BOP>
P49723
Q96CB9
NSUN4_HUMAN
NOL1/NOP2/Sun domain family member 4
Homo
<M><A><A><L><T><L><R><G><V><R><E><L><L><K><R><V><D><L><A><T><V><P><R><R><H><R><Y><K><K><K><W><A><A><T><E><P><K><F><P><A><V><R><L><A><L><Q><N><F><D><M><T><Y><S><V><Q><F><G><D><L><W><P><S><I><R><V><S><L><L><S><E><Q><K><Y><G><A><L><V><N><N><F><A><A><W><D><H><V><S><A><K><L><E><Q><L><S><A><K><D><F><V><N><E><A><I><S><H><W><E...
Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Target...
Q96CB9
Q66H38
GAR3_RAT
Protein FAM71B
Rattus
<M><S><S><E><C><L><L><P><Y><Y><T><A><H><S><Y><R><S><M><G><V><F><N><T><S><M><G><N><L><Q><R><Q><L><Y><K><G><G><E><Y><D><I><F><K><Y><A><P><M><F><E><S><D><F><I><Q><I><S><K><K><G><E><V><I><D><V><H><N><R><V><R><M><V><T><V><C><I><A><S><T><S><P><V><L><P><L><P><D><V><M><L><L><A><R><P><A><K><V><C><E><E><H><A><R><R><A><R><F><I><K...
May be involved in RNA biogenesis.<BOP>
Q66H38
Q04TF0
TPIS_LEPBJ
Triose-phosphate isomerase
Leptospira
<M><R><K><T><V><I><A><G><N><W><K><M><N><L><S><E><K><E><A><L><S><L><A><H><S><I><K><E><K><I><P><A><I><S><K><G><R><I><S><M><I><F><P><S><T><L><H><L><A><G><V><A><K><I><L><Q><G><T><E><I><L><V><G><A><Q><N><V><Y><P><S><G><L><A><A><F><T><G><E><T><S><P><E><Q><L><K><E><L><G><V><K><V><V><M><I><G><H><S><E><R><R><Q><F><L><G><E><T><N...
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP>
Q04TF0
P61695
IF1_THET2
Translation initiation factor IF-1
Thermus
<M><A><K><E><K><D><T><I><R><T><E><G><V><V><T><E><A><L><P><N><A><T><F><R><V><K><L><D><S><G><P><E><I><L><A><Y><I><S><G><K><M><R><M><H><Y><I><R><I><L><P><G><D><R><V><V><V><E><I><T><P><Y><D><P><T><R><G><R><I><V><Y><R><K>
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-...
P61695
P74035
RIMM_SYNY3
Ribosome maturation factor RimM
unclassified Synechocystis
<M><A><E><P><M><T><E><Q><Q><K><T><E><N><W><L><E><I><G><T><I><V><A><A><Q><G><I><Q><G><E><V><R><V><L><S><A><S><D><F><P><A><R><F><L><T><K><G><Q><R><W><I><R><K><T><P><Q><E><T><P><Q><P><L><T><L><K><K><G><K><Q><I><P><G><K><N><L><Y><I><L><R><F><T><E><I><T><D><R><N><Q><A><E><A><L><V><N><Y><Q><L><L><V><P><A><T><D><R><L><P><L><E...
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosoma...
P74035
B7V3I5
HUTI_PSEA8
Imidazolone-5-propionate hydrolase
Pseudomonas
<M><K><R><L><W><Q><H><C><H><A><A><T><L><K><G><G><K><Y><S><I><V><E><D><A><A><L><V><T><D><G><P><L><I><H><W><I><G><P><R><A><E><L><P><P><G><D><Y><A><E><R><I><D><L><G><G><A><W><L><T><P><G><L><I><D><C><H><T><H><A><V><F><G><G><N><R><S><G><E><F><E><Q><R><L><E><G><V><S><Y><A><V><I><A><A><A><G><G><G><I><A><S><T><V><R><A><T><R><E...
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.<BOP>
B7V3I5
Q5RE48
AKTIP_PONAB
Fused toes protein homolog
Pongo
<M><N><P><F><W><S><M><S><T><S><S><V><R><K><R><S><E><G><E><E><K><T><L><T><G><D><V><K><T><S><P><P><R><T><A><P><K><K><Q><L><P><S><I><P><K><N><A><L><P><I><T><K><P><T><S><P><A><P><A><A><Q><S><T><N><G><T><H><A><S><Y><G><P><F><Y><L><E><Y><S><L><L><A><E><F><T><L><V><V><K><Q><K><L><P><G><V><Y><V><Q><P><S><Y><R><S><A><L><M><W><F...
Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/...
Q5RE48
Q7CG87
SURA_YERPE
Rotamase SurA
Yersinia
<M><K><N><W><R><T><L><I><L><G><L><V><I><C><A><N><T><A><F><A><A><P><Q><E><V><D><K><V><A><A><V><V><D><N><G><V><V><L><Q><S><D><I><D><G><L><L><Q><S><V><K><M><N><A><Q><Q><S><G><Q><Q><V><P><D><D><S><T><L><R><H><Q><I><L><E><R><L><I><M><D><N><I><Q><L><Q><M><A><K><K><M><G><I><T><I><T><D><Q><A><L><D><K><A><I><A><D><I><A><A><Q><N...
Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps o...
Q7CG87
C6C0F7
MTNA_MARSD
S-methyl-5-thioribose-1-phosphate isomerase
Maridesulfovibrio
<M><T><E><H><I><Q><F><S><P><E><K><D><A><L><V><L><L><D><Q><R><Y><L><P><T><R><E><D><W><F><D><C><K><T><T><D><D><I><V><E><A><L><V><V><M><V><V><R><G><A><P><A><I><G><V><T><A><A><Y><G><C><Y><L><A><G><R><E><V><A><G><S><A><D><W><K><A><E><L><E><K><N><L><D><K><I><E><N><A><R><P><T><A><V><N><L><R><W><A><V><R><E><M><K><R><I><W><A><E...
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).<BOP>
C6C0F7
A2BIS8
GGGPS_HYPBU
Phosphoglycerol geranylgeranyltransferase
Hyperthermus
<M><K><L><G><K><V><E><R><L><L><R><S><R><V><E><S><G><E><K><L><F><L><L><L><S><D><P><E><K><P><I><S><P><N><T><V><K><L><F><E><E><N><G><A><D><V><L><L><I><G><G><S><L><N><V><T><P><Y><D><I><D><E><Y><I><A><R><L><R><V><E><G><V><K><L><P><I><V><L><F><P><G><G><L><N><N><I><A><K><S><A><D><A><I><L><F><M><T><L><M><N><S><M><D><P><Y><W><I...
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.<BOP>
A2BIS8
Q9BGQ6
CF120_MACFA
UPF0669 protein C6orf120 homolog
Macaca
<M><A><A><P><R><G><R><A><A><P><W><T><T><A><L><L><L><L><L><T><S><Q><I><L><S><P><G><S><C><A><D><E><E><E><V><P><E><E><W><V><L><L><H><V><V><Q><G><Q><I><G><A><G><N><Y><S><Y><L><R><L><N><H><E><G><K><I><V><L><R><M><R><S><L><K><G><D><A><D><L><Y><V><S><A><S><S><L><H><P><S><F><D><D><Y><E><L><Q><S><A><T><C><G><P><D><A><V><S><I><P...
May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes.<BOP>
Q9BGQ6
Q98KJ4
MIAA_RHILO
Isopentenyl-diphosphate:tRNA isopentenyltransferase
Mesorhizobium
<M><S><G><I><E><N><S><G><A><D><A><G><E><G><R><V><K><N><A><I><L><I><A><G><P><T><A><S><G><K><S><A><L><A><L><D><L><A><E><R><A><G><G><V><I><V><N><S><D><S><M><Q><G><Y><S><V><L><D><V><L><T><A><R><P><E><A><A><D><L><A><R><V><P><H><F><L><Y><G><H><V><H><P><G><T><A><Y><S><T><G><A><W><L><R><D><V><M><K><L><I><D><D><G><M><L><S><R><R...
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).<BOP>
Q98KJ4
Q3Z6L5
TSAD_DEHM1
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Dehalococcoides
<M><K><I><L><G><I><E><S><S><C><D><E><T><A><A><A><V><V><A><D><G><V><N><I><L><S><N><R><V><S><S><Q><I><D><I><H><S><R><Y><G><G><V><V><P><E><V><A><S><R><Q><H><L><L><S><I><L><P><V><I><S><D><A><L><K><E><A><R><T><G><F><D><E><I><S><A><I><A><V><T><N><G><P><G><L><A><G><S><L><I><V><G><V><N><A><A><K><A><I><A><A><A><R><G><I><P><L><V...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
Q3Z6L5
Q6NJ37
CH601_CORDI
Chaperonin-60 1
Corynebacterium
<M><A><K><L><I><A><F><N><Q><E><A><R><E><G><I><L><K><G><V><D><A><L><A><N><A><V><K><V><T><L><G><P><R><G><R><N><V><V><L><Q><K><A><F><G><S><P><T><V><T><N><D><G><V><T><I><A><R><E><I><D><L><S><D><P><F><E><N><L><G><A><Q><L><V><K><S><V><A><V><K><T><N><D><I><A><G><D><G><T><T><T><A><T><L><L><A><Q><A><V><V><T><E><G><L><R><N><V><A...
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP>
Q6NJ37
B8IS92
RL16_METNO
50S ribosomal protein L16
Methylobacterium
<M><L><Q><P><K><K><T><K><F><R><K><Q><F><K><G><R><I><H><G><A><A><K><G><G><T><D><L><N><F><G><S><Y><G><L><K><A><L><E><P><E><R><V><T><A><R><Q><I><E><A><A><R><R><A><I><T><R><E><M><K><R><Q><G><R><V><W><I><R><I><F><P><D><V><P><V><T><Q><K><P><T><E><V><R><M><G><S><G><K><G><S><P><E><Y><W><A><A><R><V><H><P><G><R><V><M><F><E><I><D...
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.<BOP>
B8IS92
Q5XXR3
ARHG6_RAT
Rac/Cdc42 guanine nucleotide exchange factor 6
Rattus
<M><N><P><E><E><R><V><V><T><W><L><I><S><L><G><V><L><E><S><P><K><K><T><I><C><D><P><E><E><F><L><K><S><S><L><K><N><G><V><V><L><C><K><L><I><S><R><L><L><P><G><S><V><E><K><Y><C><Q><E><P><Q><T><E><A><D><C><I><D><N><I><N><D><F><L><K><G><C><A><T><L><Q><V><E><V><F><E><P><D><D><L><Y><S><G><A><N><F><S><K><V><L><N><T><L><L><A><V><N...
Acts as a RAC1 guanine nucleotide exchange factor (GEF).<BOP>
Q5XXR3
Q4QLI9
ZIPA_HAEI8
Cell division protein ZipA
Haemophilus
<M><D><L><N><T><I><L><I><I><V><G><I><V><A><L><V><A><L><I><V><H><G><L><W><S><N><R><R><E><K><S><K><Y><F><D><K><A><N><K><F><D><R><T><S><P><T><S><R><S><H><T><Q><E><E><M><V><Q><P><N><N><I><S><P><N><T><Y><V><E><N><G><H><T><P><I><S><Q><P><T><T><E><K><L><P><S><E><A><E><L><I><D><Y><R><Q><S><D><K><S><V><D><D><I><K><I><S><I><P><N...
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.<BOP>
Q4QLI9
P0DKZ0
CKR1B_CONRO
Conantokin Rl-B
Asprella
<M><Q><L><Y><T><Y><L><Y><L><L><V><P><L><V><T><F><H><L><I><L><G><T><G><T><L><D><H><G><D><A><L><T><E><R><R><S><T><D><A><T><A><L><K><P><E><P><V><L><L><Q><K><S><S><A><R><S><T><N><D><N><G><K><D><T><Q><M><K><R><I><L><K><K><R><G><N><K><A><R><G><E><E><E><L><A><E><K><A><P><E><F><A><R><E><L><A><N>
Conantokins inhibit N-methyl-D-aspartate (NMDA) receptors. This toxin has antagonist activity on the NR2B/GRIN2B subunit (IC(50)=0.1 uM) . In vivo, when delivered into the brain, is active has anticonvulsant activity in the model of epilepsy in mice .<BOP>
P0DKZ0
Q9A8J5
NRDR_CAUVC
Transcriptional repressor NrdR
Caulobacter
<M><R><C><P><F><C><G><H><A><E><S><Q><V><K><D><S><R><P><S><E><D><G><A><A><I><R><R><R><R><M><C><P><E><C><G><G><R><F><T><T><F><E><R><V><Q><L><R><E><L><I><I><V><K><R><S><G><R><R><S><P><F><D><R><D><K><L><V><R><S><V><G><L><A><T><Q><K><R><P><V><D><P><E><R><V><E><R><M><V><N><G><I><V><R><Q><L><E><S><M><G><E><T><E><L><P><S><S><T...
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.<BOP>
Q9A8J5
Q126K7
ACPS_POLSJ
4'-phosphopantetheinyl transferase AcpS
unclassified Polaromonas
<M><I><Y><G><V><G><T><D><I><C><D><V><R><R><I><R><A><S><L><E><R><H><G><E><R><L><A><Q><K><I><L><S><E><A><E><L><A><T><W><K><E><R><S><E><R><W><P><D><R><G><V><R><Y><L><A><T><R><F><S><A><K><E><A><F><S><K><A><I><G><L><G><M><R><M><P><M><T><W><R><H><C><E><I><S><K><A><A><S><G><K><P><E><I><V><L><H><G><P><L><K><D><W><F><E><T><R><Q...
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.<BOP>
Q126K7
A6MMV2
RBL_ILLOL
Ribulose bisphosphate carboxylase large chain
Illicium
<M><S><P><K><T><E><T><K><A><S><V><G><F><K><A><G><V><K><D><Y><R><L><T><Y><Y><T><P><E><Y><E><T><K><E><T><D><I><L><A><A><F><R><V><T><P><Q><P><G><V><P><P><E><E><A><G><A><A><V><A><A><E><S><S><T><G><T><W><T><T><V><W><T><D><G><L><T><S><L><D><R><Y><K><G><R><C><Y><H><I><E><P><V><A><G><E><E><N><Q><Y><I><A><Y><V><A><Y><P><L><D><L...
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.<BOP>
A6MMV2
A1JMW4
RUTF_YERE8
NADH:flavin oxidoreductase
Yersinia
<M><Q><T><Q><S><L><P><T><D><S><L><P><A><S><S><A><L><R><S><V><A><V><D><K><Q><D><F><R><D><A><M><A><R><L><G><S><A><V><N><I><I><T><T><D><G><P><A><G><R><A><G><F><T><A><S><A><V><C><S><V><T><D><T><P><P><T><L><L><V><C><L><N><R><S><A><S><V><Y><S><V><F><Q><Q><N><Q><T><L><C><V><N><T><L><C><A><E><H><E><S><L><S><N><L><F><G><G><K><T...
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.<BOP>
A1JMW4
Q52221
REP7_ECOLX
Replication-associated protein
Escherichia
<M><A><G><L><K><N><T><S><Y><N><A><V><H><W><S><Q><L><A><P><E><E><Q><I><R><F><W><E><D><Y><E><A><G><R><A><T><T><F><L><V><E><P><E><R><K><R><T><K><R><R><R><G><E><H><S><T><K><P><K><C><E><N><P><S><W><Y><R><P><E><R><Y><K><A><L><K><G><Q><L><G><H><A><Y><N><R><L><V><K><K><D><P><V><T><G><E><Q><S><L><R><M><R><M><S><R><H><P><F><Y><V...
Binds specifically to the motif 5'-AANCYGCAA-3' (repA box) in the origin of replication. Acts preferentially in cis; binding to the repA boxes is sequential, with the boxes closest to the DnaA binding site being occupied first. It is involved in promoting open complex formation by unwinding the oriB at sequence 5'-TCTT...
Q52221
P26872
RT13_MARPO
Ribosomal protein S13, mitochondrial
Marchantia
<M><S><Y><I><L><G><T><N><L><N><S><N><K><Q><V><K><I><A><L><T><R><I><F><G><I><G><P><K><K><A><I><Q><V><C><D><Q><L><G><L><S><D><T><I><K><V><N><K><L><T><K><Y><Q><F><D><Q><I><L><K><I><I><S><Q><N><Y><L><V><D><S><E><L><K><R><V><I><Q><R><D><I><K><R><L><I><S><I><G><C><Y><R><G><F><R><H><N><A><G><L><P><L><R><G><Q><R><T><H><T><N><A...
Located at the top of the head of the small subunit, it contacts several helices of the 18S rRNA.<BOP>
P26872
O82243
GH39_ARATH
Auxin-responsive GH3-like protein 9
Arabidopsis
<M><D><V><M><K><L><D><H><D><S><V><L><K><E><L><E><R><I><T><S><K><A><A><E><V><Q><D><N><I><L><R><G><I><L><E><R><N><K><D><T><E><Y><L><S><K><Y><M><N><G><S><K><D><V><L><E><F><K><R><A><V><P><I><I><I><Y><K><D><I><Y><P><Y><I><Q><R><I><A><N><G><E><D><S><S><L><I><T><G><H><S><I><T><E><I><L><C><S><S><G><T><S><A><G><E><P><K><L><M><P...
Catalyzes the synthesis of indole-3-acetic acid (IAA)-amino acid conjugates, providing a mechanism for the plant to cope with the presence of excess auxin.<BOP>
O82243
B3SGL0
BCH_GENLU
Beta-carotene 3-hydroxylase, chloroplastic
Gentiana
<M><E><T><Q><F><L><V><S><G><R><N><S><N><I><H><C><R><I><D><S><I><S><S><S><S><L><T><P><K><S><S><P><V><S><T><S><T><P><T><L><V><V><F><P><P><F><K><L><V><S><K><S><L><R><T><R><S><K><P><R><L><T><V><C><F><V><L><E><E><K><E><L><R><G><K><L><V><V><A><S><D><D><D><D><G><A><G><E><V><R><K><Q><R><E><K><E><I><S><A><S><A><E><K><L><A><Q><K...
Nonheme diiron monooxygenase involved in the biosynthesis of xanthophylls. Specific for beta-ring hydroxylations of beta-carotene. Uses ferredoxin as an electron donor.<BOP>
B3SGL0
F4JZ24
P4H10_ARATH
Probable prolyl 4-hydroxylase 10
Arabidopsis
<M><M><A><R><P><R><N><H><R><P><S><A><R><K><S><S><H><S><T><L><V><F><A><V><L><I><M><S><T><F><V><I><L><I><L><L><A><F><G><I><L><S><V><P><S><N><N><A><G><S><S><K><A><N><D><L><T><S><I><V><R><K><T><L><Q><R><S><G><E><D><D><S><K><N><E><R><W><V><E><I><I><S><W><E><P><R><A><S><V><Y><H><N><F><L><T><K><E><E><C><K><Y><L><I><E><L><A><K...
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in proline-rich peptide sequences of plant glycoproteins and other proteins. Hydroxyprolines are important constituent of many plant cell wall glycoproteins such as extensins, hydroxyproline-rich glycoproteins, lectins and arabino...
F4JZ24
A5DV09
GET1_LODEL
Guided entry of tail-anchored proteins 1
Lodderomyces
<M><L><T><L><D><I><D><P><Y><T><I><L><V><T><S><F><L><I><L><A><I><Q><K><L><V><T><V><I><G><K><Q><K><I><Q><L><Y><I><W><Q><I><Y><T><K><Y><L><S><H><S><Q><S><I><K><Q><F><N><L><K><Q><K><E><I><K><D><L><T><K><Q><Q><K><L><I><S><A><Q><D><E><Y><A><K><W><T><K><I><N><R><A><L><D><K><L><K><L><E><V><Q><E><L><N><E><T><I><A><G><E><K><T><R...
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD...
A5DV09
Q9ZEJ7
ISPT_TRIV2
Isoprenyl transferase
Trichormus
<M><T><I><Q><Q><T><E><L><Q><E><L><P><L><D><L><K><R><E><L><L><P><K><H><V><A><V><I><M><D><G><N><G><R><W><A><K><R><Q><G><L><P><R><I><M><G><H><K><R><G><V><D><A><L><K><D><L><L><R><C><C><R><D><W><G><I><Q><A><L><T><A><Y><A><F><S><T><E><N><W><K><R><P><Q><E><E><V><E><F><L><M><T><L><F><Q><R><V><L><R><Q><E><L><R><E><M><V><E><E><N...
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.<BOP>
Q9ZEJ7
B6JJT0
PCKA_AFIC5
Phosphoenolpyruvate carboxykinase (ATP)
Afipia
<M><D><Q><S><G><V><R><N><D><A><F><G><V><D><K><F><G><L><K><N><L><K><A><V><H><W><N><L><G><T><A><A><L><Y><E><Y><A><L><R><N><G><E><A><E><L><T><R><E><G><A><L><C><A><E><T><G><E><F><T><G><R><S><P><K><D><K><Y><T><V><R><D><A><L><T><D><K><T><M><S><W><S><T><N><Q><S><I><T><P><E><Q><F><A><V><L><H><A><D><F><I><K><H><A><E><G><M><T><L...
Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.<BOP>
B6JJT0
Q8RQN1
AK_COREF
Aspartate kinase
Corynebacterium
<M><A><L><V><V><Q><K><Y><G><G><S><S><L><E><S><A><E><R><I><R><N><V><A><E><R><I><V><A><T><K><K><A><G><N><D><V><V><V><V><C><S><A><M><G><D><T><T><D><E><L><L><D><L><A><A><A><V><N><P><V><P><P><A><R><E><M><D><M><L><L><T><A><G><E><R><I><S><N><A><L><V><A><M><A><I><E><S><L><G><A><E><A><Q><S><F><T><G><S><Q><A><G><V><L><T><T><E><R...
Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine.<BOP>
Q8RQN1
Q6D3L8
END4_PECAS
Endonuclease IV
Pectobacterium
<M><K><Y><I><G><A><H><V><S><A><A><G><G><V><D><Q><A><V><I><R><A><H><E><I><K><A><T><A><F><A><L><F><T><K><N><Q><R><Q><W><Q><A><A><P><L><S><T><E><V><I><D><R><F><K><A><A><C><E><Q><Y><A><Y><M><S><A><Q><I><L><P><H><D><S><Y><L><I><N><L><G><H><P><D><G><E><A><L><E><K><S><R><I><A><F><I><D><E><M><S><R><C><Q><L><L><G><L><S><L><L><N...
Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.<BOP>
Q6D3L8
O66646
LOLD_AQUAE
Lipoprotein-releasing system ATP-binding protein LolD
Aquifex
<M><A><E><I><L><R><A><E><N><I><K><K><V><I><R><G><Y><E><I><L><K><G><I><S><L><S><V><K><K><G><E><F><V><S><I><I><G><A><S><G><S><G><K><S><T><L><L><Y><I><L><G><L><L><D><A><P><T><E><G><K><V><F><L><E><G><K><E><V><D><Y><T><N><E><K><E><L><S><L><L><R><N><R><K><L><G><F><V><F><Q><F><H><Y><L><I><P><E><L><T><A><L><E><N><V><I><V><P><M...
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.<BOP>
O66646