accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P42701 | I12R1_HUMAN | IL-12 receptor beta component | Homo | <M><E><P><L><V><T><W><V><V><P><L><L><F><L><F><L><L><S><R><Q><G><A><A><C><R><T><S><E><C><C><F><Q><D><P><P><Y><P><D><A><D><S><G><S><A><S><G><P><R><D><L><R><C><Y><R><I><S><S><D><R><Y><E><C><S><W><Q><Y><E><G><P><T><A><G><V><S><H><F><L><R><C><C><L><S><S><G><R><C><C><Y><F><A><A><G><S><A><T><R><L><Q><F><S><D><Q><A><G><V><S><V... | Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably thro... | P42701 |
A3PGM5 | RS8_CERS1 | 30S ribosomal protein S8 | Cereibacter | <M><S><V><N><D><P><L><G><D><M><L><T><R><I><R><N><A><Q><L><R><G><K><S><T><V><S><T><P><A><S><R><L><R><A><W><V><L><D><V><L><Q><A><E><G><Y><I><R><G><Y><E><K><K><E><T><E><N><G><Q><G><E><L><V><I><S><L><K><Y><F><E><G><T><P><V><I><R><E><L><K><R><V><S><K><P><G><R><R><V><Y><M><A><T><K><D><L><P><S><V><R><N><G><L><G><V><S><I><I><S... | One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP> | A3PGM5 |
A7FM66 | MURG_YERP3 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase | Yersinia | <M><S><G><K><T><K><R><L><M><V><M><A><G><G><T><G><G><H><V><F><P><G><L><A><V><A><H><H><L><M><A><Q><G><W><Q><V><R><W><L><G><T><A><D><R><M><E><A><S><L><V><P><Q><H><G><I><E><I><D><F><I><K><I><S><G><L><R><G><K><G><L><M><A><Q><L><T><A><P><I><R><I><Y><R><A><V><R><Q><A><Q><K><I><M><R><D><Y><Q><P><D><V><V><L><G><M><G><G><Y><V><S... | Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).<BOP> | A7FM66 |
O04979 | LONP2_SPIOL | Lon protease homolog 2, peroxisomal | Spinacia | <M><A><E><A><V><E><L><P><S><R><L><G><I><L><A><F><R><N><K><V><L><L><P><G><A><I><I><R><I><R><C><T><S><P><S><S><V><K><L><V><E><Q><E><L><W><Q><R><E><E><K><G><L><I><G><I><V><P><V><R><D><A><S><E><S><A><S><V><A><P><V><L><Y><P><G><G><G><T><D><S><G><E><R><N><V><K><S><Q><P><G><L><S><D><S><R><K><A><D><G><K><S><Q><Q><E><A><V><H><W... | ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.<BOP> | O04979 |
Q4ZWR6 | LPXA_PSEU2 | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase | Pseudomonas syringae | <M><S><L><I><D><P><R><A><I><I><D><P><T><A><V><L><A><D><N><V><E><V><G><P><W><S><I><I><G><P><G><V><E><I><G><E><G><T><V><V><G><P><H><V><V><L><K><G><P><T><R><I><G><K><H><N><R><I><Y><Q><F><S><S><V><G><E><D><T><P><D><L><K><Y><K><G><E><E><T><R><L><V><I><G><D><H><N><V><I><R><E><G><V><T><I><H><R><G><T><V><Q><D><R><A><E><T><T><L... | Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP> | Q4ZWR6 |
Q9Y817 | RAV1_SCHPO | RAVE complex subunit rav1 | Schizosaccharomyces | <M><P><L><A><F><T><N><P><G><T><P><L><K><R><T><A><A><Y><D><N><V><Q><W><N><Q><N><R><I><L><T><F><G><T><R><Y><T><V><L><I><I><V><N><N><Y><E><S><Y><Q><N><I><Q><F><G><E><S><I><G><A><V><A><L><D><Q><R><T><G><F><L><A><I><A><H><G><Q><V><L><D><I><Y><K><P><A><D><S><L><K><W><T><H><H><Y><N><Y><I><T><Q><L><S><E><D><I><T><Q><L><S><W><G... | Component of the RAVE complex which is required for stable assembly of the vacuolar ATPase complex V-ATPase.<BOP> | Q9Y817 |
P0DKU6 | APOC4_COLGU | Apolipoprotein C4 | Colobus | <M><S><L><L><R><N><R><L><Q><D><L><P><A><L><C><L><C><V><L><V><L><A><C><I><G><A><C><Q><S><E><A><H><E><E><T><P><S><P><P><P><K><L><K><M><S><H><W><S><L><V><T><G><R><M><K><E><L><L><E><P><V><V><N><R><T><R><D><R><W><Q><W><F><W><S><P><S><T><F><R><G><F><M><Q><T><Y><Y><D><D><H><L><R><D><L><G><P><R><T><K><A><W><L><L><K><S><K><D><S... | May participate in lipoprotein metabolism.<BOP> | P0DKU6 |
P47134 | BIR1_YEAST | Protein BIR1 | Saccharomyces | <M><D><G><Q><I><D><K><M><E><K><R><Y><S><M><T><K><L><E><N><R><L><R><T><F><Q><D><G><V><A><L><E><K><K><K><L><K><W><S><F><K><V><I><P><Y><Q><A><M><A><K><L><G><F><Y><F><D><P><V><I><D><P><K><T><S><K><L><K><K><D><S><V><R><C><C><Y><C><H><R><Q><T><Y><N><V><R><D><C><R><S><K><R><K><D><V><L><E><T><L><S><N><I><M><R><Q><H><L><T><V><T... | Seems to act in the pleiotropic control of cell division. May participate in chromosome segregation events.<BOP> | P47134 |
Q4UY33 | PEPQ_XANC8 | Proline dipeptidase | Xanthomonas | <M><T><Q><P><S><L><S><V><L><Y><S><D><H><L><R><T><L><T><A><R><A><D><Q><A><L><Q><R><G><G><F><D><H><L><V><I><P><S><G><T><T><H><Y><Q><L><F><D><D><R><D><Y><P><F><A><V><N><P><Q><F><K><A><W><V><P><L><T><R><M><P><H><S><W><L><V><Y><T><P><G><K><R><P><T><V><I><F><Y><Q><P><F><D><Y><W><H><V><V><P><D><A><P><S><G><W><W><V><E><H><C><D... | Splits dipeptides with a prolyl residue in the C-terminal position.<BOP> | Q4UY33 |
Q8TYV3 | ATGT_METKA | Archaeal tRNA-guanine transglycosylase | Methanopyrus | <M><N><V><A><F><E><V><K><D><R><D><V><A><G><R><L><G><R><L><E><V><N><G><R><R><L><K><T><P><A><L><L><P><V><V><N><P><N><K><P><T><L><D><P><R><E><I><S><K><L><G><F><D><G><V><I><T><N><A><Y><I><I><R><K><H><E><H><L><R><E><Q><A><L><E><E><G><V><H><G><L><L><G><F><D><G><F><V><M><T><D><S><G><S><F><Q><L><A><E><Y><G><D><V><E><V><S><N><E... | Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.<BOP> | Q8TYV3 |
Q5M9I5 | QCR6_RAT | Ubiquinol-cytochrome c reductase complex 11 kDa protein | Rattus | <M><G><L><E><D><E><R><K><M><L><T><G><S><G><D><P><K><E><E><E><E><E><E><L><V><D><P><L><T><T><V><R><E><H><C><E><Q><L><E><K><C><V><K><A><R><E><R><L><E><S><C><D><R><R><V><S><S><R><S><Q><T><E><E><D><C><T><E><E><L><F><D><F><L><H><A><R><D><H><C><V><A><H><K><L><F><K><S><L><K> | Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidor... | Q5M9I5 |
Q1IEX2 | HEM1_PSEE4 | Glutamyl-tRNA reductase | Pseudomonas | <M><A><F><L><A><L><G><I><N><H><K><T><A><S><V><D><V><R><E><R><V><A><F><T><P><E><Q><L><V><D><A><L><Q><Q><L><C><R><L><T><A><S><R><E><A><A><I><L><S><T><C><N><R><S><E><L><Y><I><E><Q><D><H><I><A><A><D><A><V><L><Q><W><L><A><D><Y><H><Q><L><S><L><D><E><L><R><A><S><A><Y><I><H><E><E><H><D><A><V><R><H><M><M><R><V><A><S><G><L><D><S... | Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).<BOP> | Q1IEX2 |
Q8DA20 | HUTU_VIBVU | Imidazolonepropionate hydrolase | Vibrio | <M><T><Q><S><Q><G><Q><D><P><R><L><D><T><S><R><T><I><R><A><P><H><G><T><T><L><R><A><K><S><W><L><T><E><A><P><L><R><M><L><M><N><N><L><D><P><D><V><A><E><H><P><H><A><L><V><V><Y><G><G><I><G><R><A><A><R><N><W><A><C><F><D><K><I><V><E><V><L><E><R><L><E><D><D><Q><T><L><L><V><Q><S><G><K><P><V><G><V><F><P><T><H><K><N><A><P><R><V><L... | Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.<BOP> | Q8DA20 |
Q8MLZ3 | PDE5_DICDI | Phosphodiesterase D | Dictyostelium | <M><M><F><S><K><R><K><S><I><R><F><N><P><E><G><D><Y><T><E><L><P><R><G><G><Y><V><V><P><S><K><L><G><G><I><Q><F><G><V><P><P><E><T><I><K><D><S><M><A><L><K><I><D><V><P><T><I><Y><V><F><P><E><E><L><W><D><R><K><T><G><I><N><A><A><E><A><E><F><P><A><Y><F><N><Y><F><I><L><K><R><K><V><S><F><V><C><T><K><E><Q><E><Q><R><I><R><I><V><F><Q... | Phosphodiesterase specific for cGMP, which is activated by cGMP but not by cAMP (Probable). Involved in the degradation of intracellular cGMP, contributes to the control of cGMP signals .<BOP> | Q8MLZ3 |
Q9FZ81 | RBL12_ARATH | Presenilins-associated rhomboid-like protein | Arabidopsis | <M><K><A><I><F><N><R><R><V><V><V><D><S><S><S><R><L><T><K><L><L><A><N><P><T><T><H><S><H><L><N><R><Q><T><F><T><S><L><Y><K><P><N><Q><S><R><H><F><R><T><H><Y><L><P><S><S><P><S><S><P><P><V><S><R><F><D><P><S><Q><L><W><R><S><E><K><I><R><G><F><F><A><S><A><L><G><N><K><A><V><K><L><G><N><L><V><E><S><R><V><G><F><I><G><S><Q><F><P><K... | Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis. Unable to cleave either of the yeast Pcp1 substrates in yeast cells.<BOP> | Q9FZ81 |
B5FN65 | ILVD_SALDC | Dihydroxy-acid dehydratase | Salmonella | <M><P><K><Y><R><S><A><T><T><T><H><G><R><N><M><A><G><A><R><A><L><W><R><A><T><G><M><T><D><S><D><F><G><K><P><I><I><A><V><V><N><S><F><T><Q><F><V><P><G><H><V><H><L><R><D><L><G><K><L><V><A><E><Q><I><E><A><S><G><G><V><A><K><E><F><N><T><I><A><V><D><D><G><I><A><M><G><H><G><G><M><L><Y><S><L><P><S><R><E><L><I><A><D><S><V><E><Y><M... | Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (... | B5FN65 |
P29109 | OLEO5_BRANA | Oleosin Bn-V | Brassica | <P><A><R><T><H><H><D><I><T><T><R><D><Q><Y><P><L><I><S><R><D><R><D><Q><Y><G><M><I><G><R><D><Q><Y><N><M><S><G><Q><N><Y><S><K><S><R><Q><I><A><K><A><T><T><A><V><T><A><G><D><S><L><L><V><L><S><S><L><T><L><V><G><T><V><I><A><L><I><V><A><T><P><L><L><V><I><F><S><P><I><L><V><P><A><L><I><T><V><A><L><L><I><T><G><F><L><S><S><G><A><F... | May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil. Probably interacts with both lipid and phospholipid moieties of lipid bodies. May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth.<BOP> | P29109 |
A1S223 | RL22_SHEAM | 50S ribosomal protein L22 | Shewanella | <M><E><V><L><A><K><H><R><F><A><R><T><S><P><Q><K><A><R><L><V><A><D><Q><I><R><G><L><P><V><A><K><A><L><E><I><L><T><F><S><P><K><K><A><A><V><L><V><K><K><V><V><D><S><A><I><A><N><A><E><H><N><E><G><A><D><I><D><D><L><K><I><A><K><V><F><V><D><E><G><P><T><M><K><R><I><M><P><R><A><K><G><R><A><D><R><I><I><K><R><T><S><H><I><T><V><V><V... | The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.<BOP> | A1S223 |
Q9CLI9 | DNAG_PASMU | DNA primase | Pasteurella | <M><K><G><S><I><P><R><T><F><I><D><D><L><L><A><K><T><D><I><V><E><L><V><N><S><R><V><K><L><K><K><A><G><R><D><Y><Q><A><C><C><P><F><H><H><E><K><T><P><S><F><T><V><S><Q><K><K><Q><F><Y><H><C><F><G><C><G><A><H><G><N><A><I><S><F><L><M><E><Y><D><K><L><E><F><V><E><A><I><E><E><L><A><G><M><L><G><L><E><I><P><R><E><N><K><P><H><F><H><G... | RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.<BOP> | Q9CLI9 |
A7ZK52 | RLMKL_ECO24 | rRNA (guanine-N(7)-)-methyltransferase RlmK | Escherichia | <M><N><S><L><F><A><S><T><A><R><G><L><E><E><L><L><K><T><E><L><E><N><L><G><A><V><E><C><Q><V><V><Q><G><G><V><H><F><K><G><D><T><R><L><V><Y><Q><S><L><M><W><S><R><L><A><S><R><I><M><L><P><L><G><E><C><K><V><Y><S><D><L><D><L><Y><L><G><V><Q><A><I><N><W><T><E><M><F><N><P><G><A><T><F><A><V><H><F><S><G><L><N><D><T><I><R><N><S><Q><Y... | Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.<BOP> | A7ZK52 |
Q12SL8 | AROB_SHEDO | 3-dehydroquinate synthase | Shewanella | <M><Q><Q><I><Q><V><N><L><G><D><R><S><Y><P><I><H><I><G><L><D><L><L><K><Q><Q><Q><T><F><Q><S><L><Q><S><K><K><V><F><I><V><T><N><D><V><V><A><P><L><Y><L><T><Q><V><K><A><A><L><A><D><C><A><S><V><D><V><F><V><L><P><D><G><E><K><N><K><D><L><A><H><L><E><Q><I><F><S><A><L><L><E><K><N><Y><A><R><D><T><T><L><L><A><L><G><G><G><V><I><G><D... | Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).<BOP> | Q12SL8 |
Q8X9Y9 | MURD_ECO57 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase | Escherichia | <M><A><D><Y><Q><G><K><N><V><V><I><I><G><L><G><L><T><G><L><S><C><V><D><F><F><L><A><R><G><V><T><P><R><V><M><D><T><R><M><T><P><P><G><L><D><K><L><P><E><A><V><E><R><H><T><G><S><L><N><D><E><W><L><M><A><A><D><L><I><V><A><S><P><G><I><A><L><A><H><P><S><L><S><A><A><A><D><A><G><I><E><I><V><G><D><I><E><L><F><C><R><E><A><Q><A><P><I... | Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).<BOP> | Q8X9Y9 |
O54438 | FABG_PSEAE | Beta-ketoacyl-ACP reductase | Pseudomonas | <M><S><L><Q><G><K><V><A><L><V><T><G><A><S><R><G><I><G><Q><A><I><A><L><E><L><G><R><L><G><A><V><V><I><G><T><A><T><S><A><S><G><A><E><K><I><A><E><T><L><K><A><N><G><V><E><G><A><G><L><V><L><D><V><S><S><D><E><S><V><A><A><T><L><E><H><I><Q><Q><H><L><G><Q><P><L><I><V><V><N><N><A><G><I><T><R><D><N><L><L><V><R><M><K><D><D><E><W><F... | Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.<BOP> | O54438 |
B8ZJV2 | Y1183_STRPJ | UPF0122 protein SPN23F11830 | Streptococcus | <M><E><I><E><K><T><N><R><M><N><A><L><F><E><F><Y><A><A><L><L><T><D><K><Q><M><N><Y><I><E><L><Y><Y><A><D><D><Y><S><L><A><E><I><A><E><E><F><G><V><S><R><Q><A><V><Y><D><N><I><K><R><T><E><K><I><L><E><D><Y><E><M><K><L><H><M><Y><S><D><Y><I><V><R><S><Q><I><F><D><Q><I><L><E><R><Y><P><K><D><N><F><L><Q><E><Q><I><E><I><L><T><S><I><D... | Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.<BOP> | B8ZJV2 |
P19730 | DMPL_PSEUF | Phenol hydroxylase P1 protein | Proteobacteria | <M><S><V><E><I><K><T><N><T><V><D><P><I><R><Q><T><Y><G><N><L><Q><R><R><F><G><D><K><P><A><S><R><Y><Q><E><A><S><Y><D><I><E><A><V><T><N><F><H><Y><R><P><L><W><D><P><Q><H><E><L><H><D><P><T><R><T><A><I><R><M><T><D><W><H><K><V><T><D><P><R><Q><F><Y><Y><G><A><Y><V><Q><T><R><A><R><M><Q><E><A><T><E><H><A><Y><G><F><C><E><K><R><E><L... | Part of a multicomponent enzyme which catalyzes the degradation of phenol and some of its methylated derivatives . DmpL, DmpN and DmpO form the oxygenase component of the complex . Required for growth on phenol and for in vitro phenol hydroxylase activity .<BOP> | P19730 |
C1BA77 | COAX_RHOOB | Pantothenic acid kinase | Rhodococcus | <M><L><L><T><V><D><V><R><N><T><N><I><V><L><G><L><F><T><G><T><G><E><H><S><K><L><V><Q><D><W><R><M><R><T><D><A><R><M><T><A><D><E><L><A><L><I><F><R><G><L><L><G><A><H><T><D><Q><I><T><G><V><S><A><L><S><T><V><P><S><V><L><R><E><I><R><V><M><L><T><R><Y><W><G><H><V><P><H><V><L><V><E><P><G><V><R><T><G><V><P><L><L><V><D><N><P><K><E... | Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.<BOP> | C1BA77 |
A5F3P9 | MURB_VIBC3 | UDP-N-acetylmuramate dehydrogenase | Vibrio | <M><Q><I><Q><L><G><A><N><L><K><P><Y><H><T><F><G><I><E><Q><L><A><A><Q><L><V><V><A><E><S><I><D><D><L><K><A><L><Y><C><S><A><E><W><A><S><L><P><K><L><I><I><G><K><G><S><N><M><L><F><T><C><H><Y><T><G><M><V><V><V><N><R><L><N><G><I><E><H><Q><Q><D><D><D><Y><H><R><L><H><V><A><G><G><E><D><W><P><S><L><V><S><W><C><V><E><Q><G><I><G><G... | Cell wall formation.<BOP> | A5F3P9 |
Q9UZK4 | KAD6_PYRAB | ATP-AMP transphosphorylase | Pyrococcus | <M><L><I><A><I><T><G><T><P><G><V><G><K><T><T><I><A><K><L><L><A><E><K><L><G><Y><E><Y><V><N><L><R><D><F><A><L><E><K><G><C><G><R><E><V><D><G><E><V><E><V><E><I><D><E><L><A><Y><F><V><E><K><E><L><K><D><R><N><V><V><L><D><G><H><L><S><H><L><M><P><V><D><L><V><V><V><L><R><A><H><P><R><I><I><G><E><R><L><R><E><R><G><Y><S><K><E><K><I... | Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.<BOP> | Q9UZK4 |
Q7ZXR3 | NAA20_XENLA | NatB catalytic subunit | Xenopus | <M><T><T><L><R><A><F><T><C><D><D><L><F><R><F><N><N><I><N><L><D><P><L><T><E><T><Y><G><I><P><F><Y><L><Q><Y><L><A><H><W><P><E><Y><F><I><V><A><E><A><P><G><G><E><L><M><G><Y><I><M><G><K><A><E><G><S><V><A><R><E><E><W><H><G><H><V><T><A><L><S><V><A><P><E><F><R><R><L><G><L><A><A><K><L><M><E><L><L><E><E><I><S><E><R><K><G><G><F><F... | Catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. Proteins with cell cycle functions are overrepresented in the pool of NatB substrates. Required for maintaining the structure and function of actomyos... | Q7ZXR3 |
B6HYN0 | MIAB_ECOSE | tRNA-i(6)A37 methylthiotransferase | Escherichia | <M><T><K><K><L><H><I><K><T><W><G><C><Q><M><N><E><Y><D><S><S><K><M><A><D><L><L><D><A><T><H><G><Y><Q><L><T><D><V><A><E><E><A><D><V><L><L><L><N><T><C><S><I><R><E><K><A><Q><E><K><V><F><H><Q><L><G><R><W><K><L><L><K><E><K><N><P><D><L><I><I><G><V><G><G><C><V><A><S><Q><E><G><E><H><I><R><Q><R><A><H><Y><V><D><I><I><F><G><P><Q><T... | Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.<BOP> | B6HYN0 |
Q2IFK0 | CH602_ANADE | Chaperonin-60 2 | Anaeromyxobacter | <M><A><A><K><E><I><V><F><D><Q><K><A><R><D><A><I><L><K><G><V><N><T><L><A><D><A><V><K><V><T><L><G><P><K><G><R><N><V><V><I><E><K><S><F><G><S><P><T><I><T><K><D><G><V><T><V><A><K><E><I><E><L><E><N><K><F><E><N><M><G><A><Q><M><V><K><E><V><A><S><K><T><S><D><V><A><G><D><G><T><T><T><A><T><V><L><A><Q><A><I><Y><R><E><G><S><K><L><V... | Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP> | Q2IFK0 |
Q6G104 | ISPG_BARQU | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase | Bartonella | <M><S><T><A><Y><S><L><S><K><P><L><E><R><R><R><S><I><A><V><T><I><G><D><V><V><V><G><G><H><S><P><I><V><V><Q><S><M><T><N><T><D><T><A><D><V><D><A><T><V><A><Q><I><A><A><L><W><Q><V><G><S><Q><L><V><R><I><T><V><D><R><D><E><A><A><A><A><V><P><K><I><R><E><R><L><E><R><L><G><F><I><V><P><L><V><G><D><F><H><Y><I><G><H><K><L><L><S><E><H... | Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.<BOP> | Q6G104 |
Q12JN9 | UBID_SHEDO | Polyprenyl p-hydroxybenzoate decarboxylase | Shewanella | <M><S><F><K><D><L><R><S><F><I><D><H><L><E><A><N><G><E><L><K><R><I><S><Y><P><V><D><P><Y><L><E><M><T><E><I><A><D><R><V><L><R><S><G><G><P><A><L><L><F><E><N><P><K><D><N><T><M><P><V><L><V><N><L><F><G><T><P><K><R><V><A><M><A><L><G><K><E><D><P><L><A><L><R><E><V><G><E><L><L><A><F><L><K><E><P><E><P><P><T><G><F><K><D><A><L><A><K... | Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP> | Q12JN9 |
P85239 | CYVA_VIOBI | Cyclotide vibi-A | Viola | <G><L><P><V><C><G><E><T><C><F><G><G><T><C><N><T><P><G><C><S><C><S><Y><P><I><C><T><R><N> | Probably participates in a plant defense mechanism.<BOP> | P85239 |
Q321N6 | ASTE_SHIBS | Succinylglutamate desuccinylase | Shigella | <M><D><N><F><L><A><L><T><L><T><G><K><K><P><V><I><T><E><R><E><I><N><G><V><R><W><R><W><L><G><D><G><V><L><E><L><T><P><L><T><P><P><Q><G><A><L><V><I><S><A><G><I><H><G><N><E><T><A><P><V><E><M><L><D><A><L><L><G><A><I><S><H><G><E><I><P><L><R><W><R><L><L><V><I><L><G><N><P><P><A><L><K><Q><G><K><R><Y><C><H><S><D><M><N><R><M><F><G... | Transforms N(2)-succinylglutamate into succinate and glutamate.<BOP> | Q321N6 |
Q03KX7 | RNH2_STRTD | Ribonuclease HII | Streptococcus | <M><A><T><I><K><E><V><K><E><Q><L><A><I><L><R><D><L><D><D><P><R><W><A><S><F><E><E><D><S><R><T><G><V><Q><A><A><I><R><K><R><R><K><A><I><L><A><E><L><A><E><E><E><R><L><E><T><L><L><N><Y><E><K><S><L><Y><A><R><G><I><E><L><I><A><G><V><D><E><V><G><R><G><P><L><A><G><P><V><V><A><A><A><V><I><L><P><K><L><C><K><I><K><G><L><N><D><S><K... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | Q03KX7 |
Q0MQE8 | NDUB9_PONAB | NADH-ubiquinone oxidoreductase B22 subunit | Pongo | <M><A><F><L><A><S><G><A><Y><L><T><H><R><Q><K><V><L><R><L><Y><K><R><A><L><R><H><L><E><S><W><C><V><Q><R><D><K><Y><R><Y><F><A><C><L><M><R><A><R><F><E><E><H><K><N><E><K><D><M><V><R><A><T><Q><L><L><K><E><A><E><E><E><F><W><Y><R><Q><H><P><Q><P><Y><I><F><P><D><S><P><G><G><T><S><Y><E><R><Y><D><C><Y><K><V><P><E><W><C><L><D><D><W... | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.<BOP> | Q0MQE8 |
Q2UET3 | MKAR_ASPOR | Microsomal beta-keto-reductase | Aspergillus subgen. Circumdati | <M><D><F><L><S><K><H><T><T><C><L><S><N><L><E><L><N><L><A><P><G><W><Q><T><V><S><A><Y><F><L><L><A><A><G><S><L><F><V><A><S><R><A><L><T><F><V><R><V><L><L><S><L><F><V><L><P><G><K><S><L><R><S><F><G><P><K><G><S><W><A><V><V><T><G><A><S><D><G><L><G><K><E><F><S><L><Q><L><A><R><A><G><F><N><I><V><L><V><S><R><T><A><S><K><L><T><T><L... | Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingol... | Q2UET3 |
Q87S51 | PPK1_VIBPA | Polyphosphoric acid kinase | Vibrio | <M><S><A><E><K><L><Y><I><E><K><E><L><S><W><L><S><F><N><E><R><V><L><Q><E><A><A><D><K><T><V><P><L><I><E><R><I><R><F><L><G><I><F><S><N><N><L><D><E><F><Y><K><V><R><F><A><D><V><K><R><R><I><L><I><N><Q><E><R><G><G><S><D><N><S><K><R><L><L><S><K><M><Q><A><K><A><L><K><L><N><E><Q><F><D><E><L><Y><S><E><L><I><R><E><M><A><R><R><R><I... | Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).<BOP> | Q87S51 |
A9W4X6 | CYSI_METEP | Sulfite reductase [NADPH] hemoprotein beta-component | Methylorubrum | <M><D><D><H><K><P><I><E><T><P><D><G><P><A><V><D><T><P><G><I><G><A><R><R><Y><E><T><P><P><T><E><L><P><I><T><E><A><E><A><A><R><A><A><G><L><A><H><N><E><H><L><K><I><A><S><G><Y><L><R><G><G><L><A><D><G><L><L><K><H><A><T><G><A><I><S><E><D><D><G><Q><L><V><K><F><H><G><M><Y><M><Q><D><D><R><D><I><R><A><E><R><T><K><K><K><L><E><K><A... | Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.<BOP> | A9W4X6 |
A0AL52 | G6PI_LISW6 | Phosphohexose isomerase | Listeria | <M><T><H><I><K><F><D><Y><S><K><A><L><R><F><F><E><E><R><E><L><D><Y><L><E><P><A><V><K><A><A><H><D><S><L><H><N><G><T><G><A><G><N><D><A><L><G><W><I><N><L><P><T><D><Y><D><K><E><E><F><A><R><I><K><K><A><T><E><K><I><H><S><D><S><D><V><L><I><V><I><G><I><G><G><S><Y><L><G><A><R><A><A><I><E><T><L><N><H><S><F><Y><N><V><L><E><K><G><A... | Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.<BOP> | A0AL52 |
Q8SS91 | FEN1_ENCCU | Flap structure-specific endonuclease 1 | Encephalitozoon | <M><G><I><K><Q><L><S><K><L><L><R><E><N><S><K><R><G><I><R><E><R><P><L><V><Y><Y><S><S><K><K><V><A><I><D><A><S><M><S><M><Y><Q><F><L><I><A><V><R><S><G><G><A><T><L><G><N><E><D><S><P><T><S><H><L><V><G><F><F><Y><R><T><I><R><M><V><E><L><G><I><T><P><V><Y><V><F><D><G><V><P><P><E><I><K><M><K><E><L><E><K><R><K><E><R><R><A><A><A><D... | Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It ente... | Q8SS91 |
Q9R0G8 | NRK_MOUSE | Nck-interacting kinase-like embryo specific kinase | Mus | <M><A><G><P><G><S><W><R><D><K><E><V><T><D><L><G><Q><L><P><D><P><T><G><I><F><S><L><D><K><A><I><G><L><G><T><Y><G><R><I><F><L><G><I><H><E><K><T><G><S><L><V><A><V><K><V><M><S><A><R><K><T><P><L><P><E><I><G><R><R><V><R><V><N><K><Y><Q><K><S><V><G><W><R><Y><S><D><E><E><E><D><L><R><T><E><L><N><L><L><R><K><Y><S><F><H><K><N><I><V... | May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway.<BOP> | Q9R0G8 |
Q3IFD1 | RSMA_PSET1 | S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase | Pseudoalteromonas | <M><T><D><K><V><H><L><G><H><R><A><R><K><R><F><G><Q><N><F><L><F><D><D><M><I><I><G><K><I><V><S><A><I><D><P><K><P><E><D><N><L><V><E><I><G><P><G><L><G><A><I><T><E><P><V><A><E><L><S><G><H><L><T><V><V><E><L><D><K><D><L><A><Q><R><L><I><E><H><P><F><L><G><P><K><L><T><V><N><Q><G><D><A><M><T><F><D><F><A><S><L><V><R><D><D><K><K><L... | Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.<BOP> | Q3IFD1 |
Q1GIM9 | NUOI_RUEST | NDH-1 subunit I | unclassified Ruegeria | <M><T><Q><I><D><Y><T><R><A><A><K><Y><F><L><L><Q><D><V><W><Q><G><F><K><L><G><L><K><Y><F><F><A><P><K><A><T><I><N><Y><P><H><E><K><G><P><L><S><P><R><F><R><G><E><H><A><L><R><R><Y><P><N><G><E><E><R><C><I><A><C><K><L><C><E><A><V><C><P><A><Q><A><I><T><I><D><A><E><P><R><E><D><G><S><R><R><T><T><R><Y><D><I><D><M><T><K><C><I><Y><C... | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t... | Q1GIM9 |
A0PXT1 | EFTU_CLONN | Elongation factor Tu | Clostridium | <M><A><R><Q><K><F><E><R><N><K><P><H><V><N><I><G><T><I><G><H><V><D><H><G><K><T><T><T><T><A><A><I><T><M><T><L><A><K><A><G><G><A><E><V><Q><N><Y><E><D><I><D><K><A><P><E><E><K><E><R><G><I><T><I><N><T><S><H><V><E><Y><E><T><E><N><R><H><Y><A><H><V><D><C><P><G><H><A><D><Y><V><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V><V><S... | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP> | A0PXT1 |
Q6B458 | LEU3_DEBHA | Beta-IPM dehydrogenase | Debaryomyces | <M><S><Q><P><E><L><K><K><S><K><V><D><I><S><K><T><I><T><V><L><P><G><D><H><V><G><E><E><V><C><N><E><A><I><K><V><L><Q><A><I><E><D><A><T><P><Y><R><N><I><K><F><N><L><Q><K><H><L><I><G><G><A><A><I><D><A><T><G><T><P><L><P><D><E><S><L><E><A><A><K><N><S><D><A><V><L><L><G><A><V><G><G><P><K><W><G><T><G><S><V><R><P><E><Q><G><L><L><K... | Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.<BOP> | Q6B458 |
Q94BT2 | AIR12_ARATH | Auxin-induced in root cultures protein 12 | Arabidopsis | <M><A><S><S><S><S><S><L><L><I><L><A><V><A><C><F><V><S><L><I><S><P><A><I><S><Q><Q><A><C><K><S><Q><N><L><N><S><A><G><P><F><D><S><C><E><D><L><P><V><L><N><S><Y><L><H><Y><T><Y><N><S><S><N><S><S><L><S><V><A><F><V><A><T><P><S><Q><A><N><G><G><W><V><A><W><A><I><N><P><T><G><T><K><M><A><G><S><Q><A><F><L><A><Y><R><S><G><G><G><A><A... | One-heme-containing cytochrome.<BOP> | Q94BT2 |
Q8ZRW2 | KEFC_SALTY | K(+)/H(+) antiporter | Salmonella | <M><D><S><H><T><L><L><Q><A><L><I><Y><L><G><S><A><A><L><I><V><P><I><A><V><R><L><G><L><G><S><V><L><G><Y><L><I><A><G><C><I><I><G><P><W><G><L><R><L><V><T><D><A><E><S><I><L><H><F><A><E><I><G><V><V><L><M><L><F><V><I><G><L><E><L><D><P><Q><R><L><W><K><L><R><A><S><V><F><G><G><G><A><L><Q><M><G><V><C><G><G><L><I><G><L><F><C><M><F... | Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.<BOP> | Q8ZRW2 |
B7IUM9 | RPOZ_BACC2 | Transcriptase subunit omega | Bacillus cereus group | <M><L><N><P><S><I><D><S><L><L><Q><K><I><D><S><K><Y><T><L><V><T><V><A><A><K><R><A><R><E><M><Q><L><A><N><N><C><V><V><E><Q><P><V><S><H><K><C><V><G><K><A><L><E><E><I><D><A><E><V><L><S><Y><V><P><S><E><D><K><V><A><E> | Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.<BOP> | B7IUM9 |
Q751K8 | FIP1_ASHGO | Pre-mRNA polyadenylation factor FIP1 | Eremothecium | <M><Q><L><R><A><A><Q><H><L><I><A><E><E><L><Q><M><A><S><S><D><D><E><D><E><K><F><L><Y><G><S><E><D><E><A><D><G><P><R><G><Q><Q><K><R><K><L><I><P><Q><G><T><A><Q><I><Q><E><P><D><T><K><R><A><R><G><A><D><D><G><D><V><D><M><L><D><D><D><D><E><E><E><D><D><D><E><D><E><D><D><E><D><S><D><S><D><V><E><I><I><I><G><T><G><A><D><S><S><K><L... | Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase.<BOP> | Q751K8 |
Q8NB42 | ZN527_HUMAN | Zinc finger protein 527 | Homo | <M><A><V><G><L><C><K><A><M><S><Q><G><L><V><T><F><R><D><V><A><L><D><F><S><Q><E><E><W><E><W><L><K><P><S><Q><K><D><L><Y><R><D><V><M><L><E><N><Y><R><N><L><V><W><L><G><L><S><I><S><K><P><N><M><I><S><L><L><E><Q><G><K><E><P><W><M><V><E><R><K><M><S><Q><G><H><C><A><D><W><E><S><W><C><E><I><E><E><L><S><P><K><W><F><I><D><E><D><E><I... | May be involved in transcriptional regulation.<BOP> | Q8NB42 |
Q61312 | AP2C_MOUSE | Activating enhancer-binding protein 2 gamma | Mus | <M><L><W><K><I><T><D><N><V><K><Y><E><E><D><C><E><D><R><H><D><S><S><S><N><G><N><P><R><I><P><H><L><S><S><P><G><Q><H><L><Y><S><P><A><P><P><L><S><H><T><G><V><A><E><Y><Q><P><P><P><Y><F><P><P><P><Y><Q><Q><L><A><Y><S><Q><S><A><D><H><Y><S><H><L><G><E><A><Y><A><A><A><M><N><P><L><H><Q><P><A><A><T><G><S><Q><Q><Q><A><W><P><G><R><Q... | Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, ... | Q61312 |
A5E958 | RLMH_BRASB | rRNA (pseudouridine-N3-)-methyltransferase RlmH | unclassified Bradyrhizobium | <M><R><I><V><V><I><A><V><G><R><L><K><Q><G><P><E><R><E><L><A><E><R><Y><R><E><R><F><D><D><L><G><R><K><L><G><F><R><G><L><D><L><H><E><L><P><E><S><R><A><R><D><A><A><T><R><I><S><E><E><A><A><A><I><A><A><L><I><P><G><R><S><V><L><V><C><L><D><E><R><G><Q><N><I><D><S><A><S><L><A><A><Q><I><G><R><W><R><D><E><G><V><P><A><A><V><F><V><I... | Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.<BOP> | A5E958 |
Q3IZN0 | PTH_CERS4 | Peptidyl-tRNA hydrolase | Cereibacter | <M><K><L><F><V><G><L><G><N><P><G><A><R><Y><A><G><N><R><H><N><I><G><Y><M><A><V><E><A><I><A><A><D><H><G><F><G><P><W><R><A><R><F><Q><G><L><T><S><E><G><R><L><G><S><E><Q><V><L><L><L><K><P><E><T><F><M><N><L><S><G><Q><S><V><G><E><A><M><R><F><Y><K><L><T><P><A><D><V><I><V><F><H><D><E><L><D><L><A><P><G><K><L><R><L><K><Q><G><G><G... | The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.<BOP> | Q3IZN0 |
Q0MQJ1 | NDUV3_GORGO | NADH-ubiquinone oxidoreductase 9 kDa subunit | Gorilla | <M><A><A><S><C><L><L><R><Q><G><R><A><G><A><L><K><T><M><L><Q><E><A><Q><V><F><R><G><L><A><S><T><V><S><L><S><A><E><S><G><K><S><E><K><G><Q><P><Q><N><S><K><K><Q><S><P><P><K><K><P><A><P><V><P><A><E><P><F><D><N><S><T><Y><K><N><L><Q><H><H><D><Y><S><T><Y><T><F><L><D><L><N><L><E><L><S><K><F><R><M><P><Q><P><S><S><G><R><E><S><P><R... | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the... | Q0MQJ1 |
C3KXC6 | EX7L_CLOB6 | Exodeoxyribonuclease VII large subunit | Clostridium | <M><H><I><K><T><L><T><V><S><Q><L><N><R><Y><V><K><N><T><L><D><A><D><F><I><L><N><N><A><S><V><K><G><E><I><S><N><L><K><I><H><S><S><G><H><I><Y><F><S><L><K><D><G><G><S><K><I><N><C><V><M><F><K><S><Y><A><Y><N><L><K><F><A><P><E><N><G><M><D><V><V><A><L><G><N><V><S><V><Y><E><K><E><G><S><Y><Q><L><Y><V><K><D><M><K><R><E><G><I><G><D... | Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.<BOP> | C3KXC6 |
Q19VA0 | RPOC2_CHLAT | Plastid-encoded RNA polymerase subunit beta'' | Chlorokybus | <M><N><L><F><F><C><N><R><T><I><E><K><G><E><I><R><R><F><I><A><W><F><I><F><H><H><G><T><A><R><T><T><Q><M><V><E><R><L><K><V><L><G><F><R><H><A><T><K><A><G><V><S><L><S><V><D><D><L><K><I><P><P><S><K><R><W><L><L><E><D><A><E><E><E><I><Q><F><T><E><R><Q><Y><Q><K><G><K><I><T><A><V><E><R><F><Q><K><V><I><D><T><W><H><S><T><S><E><T><L... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP> | Q19VA0 |
Q3J277 | ARGC_CERS4 | N-acetyl-glutamate semialdehyde dehydrogenase | Cereibacter | <M><V><Q><N><I><A><I><L><G><A><S><G><Y><T><G><A><E><L><V><R><L><I><A><T><H><P><A><M><R><I><V><A><L><S><G><D><R><K><A><G><M><A><M><S><E><V><F><P><F><L><R><H><L><D><L><P><R><L><Q><K><I><E><E><I><D><F><S><S><V><D><L><A><F><C><A><L><P><H><A><T><S><Q><A><V><I><A><G><L><P><R><D><L><K><V><V><D><L><S><A><D><F><R><L><R><D><P><A... | Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.<BOP> | Q3J277 |
Q8TI34 | OGT_METAC | O-6-methylguanine-DNA-alkyltransferase | Methanosarcina | <M><Y><Y><A><I><F><E><S><P><I><G><P><I><L><L><A><G><D><E><E><G><L><K><Y><V><N><F><M><K><G><K><K><K><I><E><V><P><D><S><W><V><E><N><E><E><F><F><R><E><A><S><R><Q><L><E><A><Y><F><A><G><E><L><K><S><F><D><V><K><L><A><P><E><G><T><E><F><Q><K><S><V><W><N><A><L><K><E><I><P><Y><G><E><T><R><T><Y><G><E><I><A><K><N><I><G><N><P><K><A... | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inac... | Q8TI34 |
Q9Z817 | LSPA_CHLPN | Signal peptidase II | Chlamydia | <M><A><T><R><F><R><S><T><L><L><V><I><T><L><F><V><L><I><D><W><V><T><K><L><V><V><L><L><Q><Y><K><D><L><Q><I><L><T><H><P><T><L><Y><T><H><S><W><G><R><F><S><F><S><I><A><P><V><F><N><E><G><A><A><F><G><L><F><S><N><Y><K><Y><F><L><F><L><L><R><I><F><V><I><L><G><L><L><A><Y><L><F><F><K><K><K><S><I><Q><S><T><T><Q><T><A><L><V><L><L><C... | This protein specifically catalyzes the removal of signal peptides from prolipoproteins.<BOP> | Q9Z817 |
A0PPH6 | EFP_MYCUA | Elongation factor P | Mycobacterium | <M><A><S><T><A><D><F><K><N><G><L><V><L><Q><I><D><G><Q><L><W><S><I><V><E><F><Q><H><V><K><P><G><K><G><P><A><F><V><R><T><K><L><K><N><V><L><S><G><K><V><V><D><K><T><Y><N><A><G><V><K><V><E><T><A><T><V><D><R><R><D><T><T><Y><L><Y><R><D><G><S><D><F><V><F><M><D><S><Q><D><Y><E><Q><H><P><L><P><E><S><L><V><G><D><A><A><R><F><L><L><E... | Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP> | A0PPH6 |
A3PIQ5 | GLGB_CERS1 | Glycogen branching enzyme | Cereibacter | <M><N><V><T><S><K><P><G><E><L><V><P><E><S><D><V><A><A><I><M><R><G><T><H><G><D><P><F><R><V><L><G><M><H><G><G><G><G><A><P><L><S><V><R><V><F><A><P><Q><A><A><E><V><A><V><L><G><Q><G><G><K><V><L><A><S><L><E><R><I><G><A><E><G><F><F><A><G><T><V><P><G><E><E><K><F><P><Y><R><L><R><F><V><S><G><P><H><E><W><E><A><D><D><P><Y><R><F><P... | Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.<BOP> | A3PIQ5 |
Q6GR37 | MET16_XENLA | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase | Xenopus | <M><A><L><N><K><S><M><H><P><R><N><R><Y><K><D><K><P><P><D><F><A><Y><L><A><S><K><Y><P><E><F><K><Q><H><V><N><V><N><L><A><G><R><V><S><L><N><F><K><D><P><C><A><V><R><A><L><T><C><T><L><L><K><E><D><F><G><L><T><I><D><I><P><L><E><R><L><I><P><T><V><P><L><R><L><N><Y><I><H><W><V><E><D><L><I><N><Y><H><D><S><D><K><T><A><L><R><R><G><I... | RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heter... | Q6GR37 |
Q46D59 | CBIM1_METBF | Energy-coupling factor transporter probable substrate-capture protein CbiM 1 | Methanosarcina | <M><H><I><F><E><G><F><L><P><G><P><W><W><Q><I><W><W><I><L><S><I><P><V><F><A><Y><G><I><F><R><L><N><K><L><V><K><E><K><P><E><V><L><P><L><I><A><V><S><G><A><V><I><F><V><L><S><S><L><K><L><P><S><V><T><G><S><T><S><H><P><T><G><T><G><M><A><V><I><L><F><G><P><A><I><T><S><V><L><S><A><I><V><L><L><Y><Q><A><L><F><L><A><H><G><G><I><T><T... | Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.<BOP> | Q46D59 |
Q32P86 | DB119_BOVIN | Defensin, beta 119 | Bos | <M><K><F><L><F><L><F><L><A><I><L><L><A><M><E><P><V><V><S><G><R><R><H><M><L><R><C><M><G><D><L><G><I><C><R><P><A><C><R><Q><S><E><E><P><Y><L><Y><C><R><N><Y><Q><P><C><C><L><P><F><Y><V><R><I><D><I><S><G><K><E><G><K><N><D><W><S><R><E><N><R><W><P><K><V><S> | Has antibacterial activity.<BOP> | Q32P86 |
P94527 | G1PDH_BACSU | sn-glycerol-1-phosphate dehydrogenase | Bacillus | <M><N><R><I><A><A><D><V><Q><R><A><F><E><N><A><G><E><K><T><L><P><I><K><V><E><E><I><V><L><G><K><Q><A><A><D><S><L><L><D><Y><V><K><R><K><N><N><Q><H><I><V><L><V><C><D><A><N><T><H><R><I><A><G><I><D><L><E><N><R><L><N><Q><E><G><F><Q><A><E><C><L><I><I><P><E><N><E><A><G><D><V><T><A><D><E><R><S><L><I><H><V><L><I><H><T><K><Q><P><T... | Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species. Prefers NADH over NADPH as coenzyme. Is also able to catalyze the reve... | P94527 |
P04843 | RPN1_HUMAN | Ribophorin-1 | Homo | <M><E><A><P><A><A><G><L><F><L><L><L><L><L><G><T><W><A><P><A><P><G><S><A><S><S><E><A><P><P><L><I><N><E><D><V><K><R><T><V><D><L><S><S><H><L><A><K><V><T><A><E><V><V><L><A><H><L><G><G><G><S><T><S><R><A><T><S><F><L><L><A><L><E><P><E><L><E><A><R><L><A><H><L><G><V><Q><V><K><G><E><D><E><E><E><N><N><L><E><V><R><E><T><K><I><K><G... | Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-... | P04843 |
Q057V8 | ACKA_BUCCC | Acetokinase | Buchnera | <M><K><K><K><L><I><L><V><L><N><C><G><S><S><S><V><K><F><S><I><I><D><V><I><E><G><V><L><Y><I><S><G><I><A><N><T><I><N><N><V><S><F><L><K><I><Y><D><I><K><K><K><I><K><I><V><K><K><N><I><S><T><D><S><Y><K><K><L><I><L><L><I><C><D><L><L><F><I><H><F><N><K><Y><L><K><L><I><I><G><I><G><H><R><I><V><H><G><G><K><D><I><K><K><S><M><I><I><N... | Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.<BOP> | Q057V8 |
Q9WZR0 | PYRG_THEMA | UTP--ammonia ligase | Thermotoga | <M><K><K><Y><V><I><V><T><G><G><V><L><S><G><I><G><K><G><I><F><S><A><S><L><A><R><L><M><K><E><H><G><V><D><V><N><V><L><K><I><D><P><Y><L><N><V><D><A><G><T><M><N><P><N><Q><H><G><E><V><F><V><T><E><D><G><Y><E><A><D><L><D><L><G><H><Y><E><R><F><L><G><R><D><M><T><R><Q><N><N><M><T><A><G><Q><V><Y><L><R><V><I><E><K><E><R><Q><G><K><Y... | Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.<BOP> | Q9WZR0 |
Q05355 | HYDL_STRHA | Putative polyketide hydroxylase | Streptomyces | <M><N><A><R><A><D><R><A><G><D><T><V><H><R><V><P><V><L><V><V><G><G><S><L><V><G><L><S><T><S><V><F><L><G><R><L><G><V><R><H><M><L><V><E><R><H><A><G><T><S><V><H><P><R><G><R><G><N><N><V><R><T><M><E><V><Y><R><A><A><G><V><E><Q><G><I><R><R><A><A><A><T><L><A><G><N><H><G><I><L><Q><T><P><S><L><V><G><D><E><G><E><W><L><L><R><D><I><D... | Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces halstedii.<BOP> | Q05355 |
B2SXG0 | COAD_PARPJ | Pantetheine-phosphate adenylyltransferase | Paraburkholderia | <M><V><V><A><V><Y><P><G><T><F><D><P><L><T><R><G><H><E><D><L><V><R><R><A><S><S><I><F><D><T><L><V><V><G><V><A><D><S><R><N><K><K><P><F><F><T><L><E><E><R><L><D><I><A><H><E><V><L><G><H><Y><P><N><V><Q><V><M><S><F><K><G><L><L><K><D><F><V><R><T><N><N><A><R><V><I><V><R><G><L><R><A><V><S><D><F><E><Y><E><F><Q><M><A><G><M><N><R><Y... | Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.<BOP> | B2SXG0 |
P57773 | CXA9_HUMAN | Gap junction alpha-10 protein | Homo | <M><G><D><W><N><L><L><G><D><T><L><E><E><V><H><I><H><S><T><M><I><G><K><I><W><L><T><I><L><F><I><F><R><M><L><V><L><G><V><A><A><E><D><V><W><N><D><E><Q><S><G><F><I><C><N><T><E><Q><P><G><C><R><N><V><C><Y><D><Q><A><F><P><I><S><L><I><R><Y><W><V><L><Q><V><I><F><V><S><S><P><S><L><V><Y><M><G><H><A><L><Y><R><L><R><V><L><E><E><E><R... | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.<BOP> | P57773 |
P78524 | DEN2B_HUMAN | Suppression of tumorigenicity 5 protein | Homo | <M><T><M><T><A><N><K><N><S><S><I><T><H><G><A><G><G><T><K><A><P><R><G><T><L><S><R><S><Q><S><V><S><P><P><P><V><L><S><P><P><R><S><P><I><Y><P><L><S><D><S><E><T><S><A><C><R><Y><P><S><H><S><S><S><R><V><L><L><K><D><R><H><P><P><A><P><S><P><Q><N><P><Q><D><P><S><P><D><T><S><P><P><T><C><P><F><K><T><A><S><F><G><Y><L><D><R><S><P><S... | May block ERK2 activation stimulated by ABL1 (Probable). May alter cell morphology and cell growth (Probable).<BOP> | P78524 |
P18980 | HBA2_SAAHA | Hemoglobin alpha-2 chain | Saara | <V><G><P><H><L><D><D><Y><G><G><E><A><L><H><R><N><F><E><V><Y><P><Q><T><K><T><Y><F><P><H><F><D><A><S><A><G><S><N><Q><L><K> | Involved in oxygen transport from the lung to the various peripheral tissues.<BOP> | P18980 |
P51574 | S15A1_RAT | null | Rattus | <M><G><M><S><K><S><R><G><C><F><G><Y><P><L><S><I><F><F><I><V><V><N><E><F><C><E><R><F><S><Y><Y><G><M><R><A><L><L><V><L><Y><F><R><N><F><L><G><W><D><D><D><L><S><T><A><I><Y><H><T><F><V><A><L><C><Y><L><T><P><I><L><G><A><L><I><A><D><S><W><L><G><K><F><K><T><I><V><S><L><S><I><V><Y><T><I><G><Q><A><V><I><S><V><S><S><I><N><D><L><T... | Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen.<BOP> | P51574 |
Q8FMI4 | ISPF_COREF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | Corynebacterium | <M><R><Q><N><R><R><F><L><R><C><Q><V><T><E><Q><I><I><P><R><V><G><I><A><S><D><A><H><Q><I><E><A><G><K><P><C><W><I><A><C><L><L><F><D><G><V><D><G><C><E><G><H><S><D><G><D><V><V><A><H><A><I><V><D><A><L><L><S><A><S><G><L><G><D><L><G><S><F><V><G><V><G><R><P><E><Y><D><G><V><S><G><T><Q><L><L><I><E><V><R><E><L><L><I><T><R><G><F><T... | Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a correspond... | Q8FMI4 |
Q8K482 | EMIL2_MOUSE | Elastin microfibril interface-located protein 2 | Mus | <M><C><Q><E><T><P><P><R><P><R><A><P><S><R><W><T><P><A><L><L><A><L><L><A><L><G><G><A><G><L><C><H><A><S><S><Q><P><G><Y><H><A><R><P><S><A><R><N><K><N><W><C><A><Y><I><V><N><K><N><V><S><C><T><V><Q><E><G><S><E><S><F><I><Q><A><Q><Y><N><C><P><W><N><Q><M><P><C><P><S><A><L><V><Y><R><V><N><F><R><P><R><F><V><T><R><Y><K><I><V><T><Q... | May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity. Major component of the cochlear basilar membrane (BM) which may contribute to the developmental... | Q8K482 |
P24127 | FUSB_BURCE | Fusaric acid resistance protein FusB | Burkholderia cepacia complex | <M><S><A><S><S><P><L><S><P><T><A><G><G><P><F><A><A><W><Y><A><A><F><G><D><W><A><R><T><D><G><A><A><W><L><Y><L><F><K><A><L><L><A><A><F><I><A><L><G><V><S><M><R><L><D><L><P><A><P><K><T><A><M><T><T><V><F><I><V><M><Q><R><K><A><A><P><C><S><R><K><A><S><T><G><S><P><A><R><S><S><G><S><S><R><R><S><R><S><S><G><C><S><R><S><S><R><S><C... | Involved in the resistance (detoxification) of the fungal toxin fusaric acid.<BOP> | P24127 |
Q7NQZ3 | COXX2_CHRVO | Heme O synthase 2 | Chromobacterium | <M><K><F><K><R><Y><L><Q><V><T><K><P><G><I><I><F><G><N><L><I><S><A><A><G><G><F><L><L><A><A><Q><G><S><V><D><W><W><L><L><A><A><T><V><V><G><L><S><L><V><V><A><S><G><C><A><I><N><N><C><I><D><Q><D><I><D><A><K><M><A><R><T><Q><K><R><V><L><V><T><G><A><M><S><T><K><A><A><L><A><H><G><V><V><L><G><L><A><G><F><A><L><L><W><F><C><T><N><P... | Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.<BOP> | Q7NQZ3 |
Q3ECM0 | PCEP2_ARATH | C-terminally encoded peptide 2.2 | Arabidopsis | <M><K><L><F><I><I><T><V><V><T><I><L><T><I><S><R><V><F><D><K><T><P><A><T><T><E><A><R><K><S><K><K><M><V><G><H><E><H><F><N><E><Y><L><D><P><T><F><A><G><H><T><F><G><V><V><K><E><D><F><L><E><V><K><K><L><K><K><I><G><D><E><N><N><L><K><N><R><F><I><N><E><F><A><P><T><N><P><E><D><S><L><G><I><G><H><P><R><V><L><N><N><K><F><T><N><D><F... | Extracellular signaling peptide that represses primary root growth rate. Regulates negatively leaves number and flowering, and modulates leaf morphology . Regulates systemic nitrogen (N)-demand signaling. Mediates up-regulation of genes involved in N uptake and assimilation pathways .<BOP> | Q3ECM0 |
Q3A3X3 | KTHY_SYNC1 | dTMP kinase | Syntrophotalea | <M><S><F><F><I><S><L><E><G><I><E><G><S><G><K><T><T><Q><I><K><R><L><A><D><R><L><E><S><L><G><H><A><V><L><I><T><R><E><P><G><G><C><P><I><A><D><Q><I><R><Q><I><L><L><H><P><D><N><G><H><L><D><P><K><A><E><L><L><L><Y><A><A><A><R><A><Q><H><V><A><E><V><I><R><P><A><L><D><Q><G><K><I><V><L><C><D><R><Y><C><D><A><T><L><A><Y><Q><G><Y><A... | Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.<BOP> | Q3A3X3 |
B5EMC8 | RIMP_ACIF5 | Ribosome maturation factor RimP | Acidithiobacillus | <M><V><N><V><E><D><R><L><Y><E><G><I><A><Q><Q><A><G><I><A><G><C><T><L><V><D><A><R><M><V><R><T><G><R><A><V><A><L><Q><V><F><I><E><K><D><E><T><T><A><V><T><I><E><D><C><A><A><V><S><R><Q><L><S><L><W><L><D><V><E><N><P><I><H><G><A><Y><R><L><E><V><S><S><P><G><L><D><R><P><L><K><N><L><H><D><F><E><R><F><K><G><S><Q><A><E><I><H><L><H... | Required for maturation of 30S ribosomal subunits.<BOP> | B5EMC8 |
B7H4T6 | PURL_BACC4 | Phosphoribosylformylglycinamidine synthase subunit II | Bacillus cereus group | <M><S><L><M><L><E><P><N><P><T><Q><I><K><E><E><R><I><Y><A><E><M><G><L><T><D><E><E><F><A><M><V><E><K><I><L><G><R><L><P><N><Y><T><E><T><G><L><F><S><V><M><W><S><E><H><C><S><Y><K><N><S><K><P><V><L><R><K><F><P><T><T><G><E><R><V><L><Q><G><P><G><E><G><A><G><I><V><D><I><G><D><N><Q><A><V><V><F><K><M><E><S><H><N><H><P><S><A><I><E... | Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three su... | B7H4T6 |
Q9CCB5 | IDER_MYCLE | Iron-dependent repressor IdeR | Mycobacterium | <M><N><D><L><V><D><T><T><E><M><Y><L><R><T><I><Y><D><L><E><E><E><G><V><T><P><L><R><A><R><I><A><E><R><L><E><Q><S><G><P><T><V><S><Q><T><V><S><R><M><E><R><D><G><L><L><R><V><A><G><N><R><H><L><E><L><T><T><K><G><R><A><M><A><I><A><V><M><R><K><H><R><L><A><E><R><L><L><V><D><V><I><G><L><P><W><E><E><V><H><A><E><A><C><R><W><E><H><V... | Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism.<BOP> | Q9CCB5 |
P29029 | CHIT_YEAST | Soluble cell wall protein 2 | Saccharomyces | <M><S><L><L><Y><I><I><L><L><F><T><Q><F><L><L><L><P><T><D><A><F><D><R><S><A><N><T><N><I><A><V><Y><W><G><Q><N><S><A><G><T><Q><E><S><L><A><T><Y><C><E><S><S><D><A><D><I><F><L><L><S><F><L><N><Q><F><P><T><L><G><L><N><F><A><N><A><C><S><D><T><F><S><D><G><L><L><H><C><T><Q><I><A><E><D><I><E><T><C><Q><S><L><G><K><K><V><L><L><S><L... | Chitinase is required for cell separation during growth of S.cerevisiae.<BOP> | P29029 |
P0C1C9 | O17A_CONDE | Gamma-conotoxin-like de7a | Kohniconus | <A><C><K><P><K><N><N><L><C><A><I><T><E><M><A><E><C><C><S><G><F><C><L><I><Y><R><C><S> | Gamma-conotoxins may act on voltage-gated non-specific cation pacemaker channels (HCN).<BOP> | P0C1C9 |
A6H4Q4 | CYB_VANPO | Cytochrome b | Vanderwaltozyma | <M><T><M><K><M><S><Y><R><K><S><N><I><Y><L><S><L><V><N><S><Y><M><I><D><S><P><Q><P><S><S><I><N><Y><W><W><N><M><G><S><L><L><G><L><C><L><V><I><Q><I><C><T><G><I><F><L><A><M><H><Y><S><S><N><I><E><L><A><F><S><S><V><E><H><I><M><R><D><V><Q><Y><G><W><L><I><R><Y><M><H><A><N><G><A><S><F><F><F><M><C><M><Y><T><H><I><A><K><G><L><Y><Y... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | A6H4Q4 |
B2JIY6 | HSCB_PARP8 | Co-chaperone protein HscB homolog | Paraburkholderia | <M><A><S><L><N><D><S><H><F><A><L><F><N><L><P><E><Q><F><G><L><D><V><S><A><L><D><R><A><Y><R><T><V><Q><A><Q><V><H><P><D><R><F><A><A><A><G><D><A><Q><K><R><I><A><M><Q><W><A><T><R><T><N><E><A><Y><Q><T><L><H><D><P><L><K><R><A><R><Y><L><L><S><L><R><G><I><D><V><G><A><E><N><N><T><A><M><E><P><A><F><L><M><Q><Q><M><E><W><R><E><S><I... | Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.<BOP> | B2JIY6 |
A5GVY2 | RS11_SYNR3 | 30S ribosomal protein S11 | unclassified Synechococcus | <M><A><K><T><A><K><K><G><P><K><K><A><K><R><N><V><P><N><G><V><A><H><I><Q><S><T><F><N><N><T><I><V><S><I><T><D><T><A><G><E><V><I><A><W><S><S><A><G><A><S><G><F><K><G><A><R><K><G><T><P><F><A><A><Q><T><A><A><E><A><A><A><R><R><A><L><E><Q><G><M><R><Q><I><E><V><L><V><R><G><P><G><S><G><R><E><T><A><I><R><A><L><Q><V><A><G><L><E><I... | Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.<BOP> | A5GVY2 |
P69997 | URE1_HELPJ | Urea amidohydrolase subunit beta | Helicobacter | <M><K><K><I><S><R><K><E><Y><V><S><M><Y><G><P><T><T><G><D><K><V><R><L><G><D><T><D><L><I><A><E><V><E><H><D><Y><T><I><Y><G><E><E><L><K><F><G><G><G><K><T><L><R><E><G><M><S><Q><S><N><N><P><S><K><E><E><L><D><L><I><I><T><N><A><L><I><V><D><Y><T><G><I><Y><K><A><D><I><G><I><K><D><G><K><I><A><G><I><G><K><G><G><N><K><D><M><Q><D><G... | Ammonia produced by ureolysis increases the gastric pH thereby providing an environment permissive for colonization of the stomach.<BOP> | P69997 |
P60057 | THND_HELPU | Hellethionin-D | Helleborus | <K><S><C><C><R><N><T><L><A><R><N><C><Y><N><A><C><R><F><T><G><G><S><Q><P><T><C><G><I><L><C><D><C><I><H><V><T><T><T><T><C><P><S><S><H><P><S> | Thionins are small plant proteins which are toxic to animal cells. They seem to exert their toxic effect at the level of the cell membrane. Their precise function is not known.<BOP> | P60057 |
Q3U319 | BRE1B_MOUSE | RING-type E3 ubiquitin transferase BRE1B | Mus | <M><S><G><L><S><N><K><R><A><A><G><D><G><G><S><G><P><P><E><K><K><M><N><R><E><E><K><T><T><T><T><L><I><E><P><I><R><L><G><G><I><S><S><T><E><E><M><D><S><K><V><L><Q><F><K><N><K><K><L><A><E><R><L><E><Q><R><Q><A><C><E><D><E><L><R><E><R><I><E><K><L><E><K><R><Q><A><T><D><D><A><T><L><L><I><V><N><R><Y><W><A><Q><L><D><E><T><V><E><A... | Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). ... | Q3U319 |
Q6DHR8 | NGBR_DANRE | Nuclear undecaprenyl pyrophosphate synthase 1 homolog | Danio | <M><A><S><L><Y><E><M><V><W><R><F><L><H><A><L><L><Y><L><Q><R><A><I><V><A><W><F><R><V><H><I><W><R><W><K><L><A><V><V><D><L><L><L><P><L><A><L><G><F><H><N><Q><K><K><T><G><P><K><G><T><R><T><S><R><R><V><R><W><G><A><D><G><R><T><L><E><K><L><P><L><H><V><G><L><L><V><T><E><E><E><I><H><Y><T><D><I><A><N><L><V><V><W><C><M><A><V><G><I... | With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolicho... | Q6DHR8 |
B4TTH8 | THIK_SALSV | Thiamine kinase | Salmonella | <M><R><S><N><N><N><N><P><L><T><R><D><E><I><L><S><R><Y><F><P><Q><Y><R><P><A><V><A><A><S><Q><G><L><S><G><G><S><C><I><I><D><H><D><T><H><R><V><V><L><R><R><H><H><D><P><D><A><P><P><A><H><F><L><R><H><Y><R><A><L><S><Q><L><P><A><S><L><A><P><R><A><L><F><Y><T><P><G><W><M><A><V><E><Y><L><H><G><V><V><N><S><A><L><P><D><A><D><E><L><A... | Catalyzes the phosphorylation of thiamine to thiamine phosphate.<BOP> | B4TTH8 |
Q0VGK4 | GDPD1_RAT | Glycerophosphodiester phosphodiesterase domain-containing protein 1 | Rattus | <M><S><S><T><A><A><F><C><L><L><S><T><L><G><G><Y><L><V><T><S><F><L><L><L><K><Y><P><A><L><L><H><Q><R><K><K><Q><R><F><L><S><R><H><I><S><H><R><G><G><A><G><E><N><L><E><N><T><M><A><A><F><Q><H><A><V><T><I><G><T><D><M><L><E><L><D><C><H><I><T><K><D><E><Q><V><V><V><S><H><D><A><N><L><K><R><S><T><G><V><N><V><N><V><S><D><L><K><Y><C... | Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylethanolamine (lyso-PE) and lysophosphatidylcholine (lyso-PC). May be involved in bioactive N-acylethanolamine biosynthesis fro... | Q0VGK4 |
P14957 | RBL_GUITH | Ribulose bisphosphate carboxylase large chain | Guillardia | <M><S><Q><S><V><E><S><R><T><R><I><K><N><E><R><Y><E><S><G><V><I><P><Y><A><K><M><G><Y><W><D><A><D><Y><V><I><K><D><T><D><V><L><A><M><F><R><M><T><P><Q><K><G><V><D><P><V><E><C><A><A><A><I><A><G><E><S><S><T><A><T><W><T><V><V><W><T><D><L><L><T><A><C><D><L><Y><R><A><K><A><Y><R><V><D><P><V><P><G><A><T><D><Q><Y><F><A><Y><I><A><Y... | RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site.<BOP> | P14957 |
B1YCN7 | SPEH_PYRNV | S-adenosylmethionine decarboxylase alpha chain | Pyrobaculum | <M><A><G><G><V><G><A><Q><I><V><G><R><H><I><Y><G><N><L><Y><G><C><E><Q><Q><I><L><K><D><E><A><A><L><I><T><I><V><K><E><A><A><K><V><A><N><A><I><L><L><S><I><G><S><Y><R><F><G><P><E><G><G><L><T><V><F><A><V><V><A><E><S><H><I><S><I><H><T><W><P><E><H><G><F><A><T><V><D><V><Y><T><C><G><D><H><T><D><P><K><A><A><F><D><Y><I><V><S><K><L... | Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.<BOP> | B1YCN7 |
A3C4H3 | BIG1L_ORYSJ | Protein BIG GRAIN 1-like | Oryza sativa | <M><R><D><M><E><M><R><W><A><A><P><A><P><A><A><R><G><R><G><R><A><R><R><R><A><P><D><Q><P><S><F><S><S><T><L><L><D><A><I><C><D><S><M><D><E><G><G><E><D><G><R><T><R><N><A><A><S><A><A><A><K><K><R><Q><E><A><A><N><S><Y><H><Y><Y><Y><C><Y><K><P><S><L><A><A><S><Y><R><A><A><P><A><L><G><S><T><A><D><C><P><G><R><G><Y><F><S><S><S><E><V... | Involved in auxin transport. Regulator of the auxin signaling pathway.<BOP> | A3C4H3 |
P0AE73 | MAZE_ECO57 | Antitoxin MazE | Escherichia | <M><I><H><S><S><V><K><R><W><G><N><S><P><A><V><R><I><P><A><T><L><M><Q><A><L><N><L><N><I><D><D><E><V><K><I><D><L><V><D><G><K><L><I><I><E><P><V><R><K><E><P><V><F><T><L><A><E><L><V><N><D><I><T><P><E><N><L><H><E><N><I><D><W><G><E><P><K><D><K><E><V><W> | Antitoxin component of a type II toxin-antitoxin (TA) system. Labile antitoxin that binds to its cognate MazF endoribonuclease toxin and neutralizes its activity. Both MazE and MazE-MazF bind to the promoter region of the mazE-mazF operon to inhibit their transcription.<BOP> | P0AE73 |
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