accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
A1T5G2 | IDI_MYCVP | Isopentenyl pyrophosphate isomerase | Mycolicibacterium | <M><P><Q><T><D><T><A><E><L><V><V><L><L><D><D><D><G><R><T><I><G><S><A><P><K><A><Q><V><H><H><A><S><T><P><L><H><L><A><F><S><C><Y><L><F><D><D><A><G><R><V><L><L><T><R><R><A><V><H><K><R><T><F><P><G><I><W><T><N><T><C><C><G><H><P><A><P><G><E><A><L><Q><D><A><V><T><R><R><V><R><E><E><L><G><V><G><I><T><D><L><R><C><V><L><P><D><F><R... | Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).<BOP> | A1T5G2 |
A7FPA8 | IBPA_YERP3 | 16 kDa heat shock protein A | Yersinia | <M><R><N><S><D><L><A><P><L><Y><R><S><A><I><G><F><D><R><L><F><N><L><L><E><S><G><Q><N><Q><S><N><G><G><Y><P><P><Y><N><V><E><L><V><D><E><N><N><Y><R><I><A><I><A><V><A><G><F><A><E><Q><E><L><E><I><T><T><Q><D><N><L><L><I><V><R><G><S><H><A><N><E><P><A><Q><R><T><Y><L><Y><Q><G><I><A><E><R><N><F><E><R><K><F><Q><L><A><E><H><I><K><I... | Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB... | A7FPA8 |
Q3IPJ1 | PSA_NATPD | Proteasome core protein PsmA | Natronomonas | <M><Q><G><Q><S><Q><Q><Q><A><Y><D><R><G><I><T><I><F><S><P><D><G><R><L><Y><Q><V><E><Y><A><R><E><A><V><K><R><G><T><A><S><I><G><I><R><T><E><D><G><V><V><L><V><V><D><K><R><I><R><S><P><L><M><E><R><T><S><V><E><K><I><H><K><A><D><D><H><I><G><I><A><S><A><G><H><V><A><D><A><R><Q><L><I><D><F><A><R><R><Q><A><Q><V><N><Q><L><R><Y><D><E... | Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.<BOP> | Q3IPJ1 |
Q3ACF5 | DDL_CARHZ | D-alanylalanine synthetase | Carboxydothermus | <M><K><I><G><V><I><C><G><G><L><S><S><E><R><E><V><S><L><R><T><G><D><A><I><F><R><A><L><L><K><K><G><Y><N><V><V><K><I><D><M><D><R><N><I><A><E><T><L><K><K><E><N><I><D><F><A><F><I><A><L><H><G><K><Y><G><E><D><G><A><I><Q><G><L><L><E><I><M><D><I><P><Y><T><G><S><G><I><L><A><S><S><L><A><I><D><K><I><M><T><K><K><I><L><K><A><E><G><I... | Cell wall formation.<BOP> | Q3ACF5 |
A2RUC4 | TYW5_HUMAN | tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase | Homo | <M><A><G><Q><H><L><P><V><P><R><L><E><G><V><S><R><E><Q><F><M><Q><H><L><Y><P><Q><R><K><P><L><V><L><E><G><I><D><L><G><P><C><T><S><K><W><T><V><D><Y><L><S><Q><V><G><G><K><K><E><V><K><I><H><V><A><A><V><A><Q><M><D><F><I><S><K><N><F><V><Y><R><T><L><P><F><D><Q><L><V><Q><R><A><A><E><E><K><H><K><E><F><F><V><S><E><D><E><K><Y><Y><L... | tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodifi... | A2RUC4 |
Q5K4E3 | POLS2_HUMAN | Serine protease 36 | Homo | <M><A><R><H><L><L><L><P><L><V><M><L><V><I><S><P><I><P><G><A><F><Q><D><S><A><L><S><P><T><Q><E><E><P><E><D><L><D><C><G><R><P><E><P><S><A><R><I><V><G><G><S><N><A><Q><P><G><T><W><P><W><Q><V><S><L><H><H><G><G><G><H><I><C><G><G><S><L><I><A><P><S><W><V><L><S><A><A><H><C><F><M><T><N><G><T><L><E><P><A><A><E><W><S><V><L><L><G><V... | Serine protease. Hydrolyzes the peptides N-t-Boc-Gln-Ala-Arg-AMC and N-t-Boc-Gln-Gly-Arg-AMC and, to a lesser extent, N-t-Boc-Ala-Phe-Lys-AMC and N-t-Boc-Val-Leu-Lys-AMC. Has a preference for substrates with an Arg instead of a Lys residue in position P1.<BOP> | Q5K4E3 |
Q6GIX4 | COPB_STAAR | Probable copper-transporting P-type ATPase B | Staphylococcus | <M><S><N><N><K><K><H><Q><N><H><E><H><H><S><H><Q><E><H><E><N><H><T><S><H><G><N><H><E><H><H><H><H><G><N><F><K><S><K><F><F><I><S><L><I><F><A><I><P><I><I><I><L><S><P><M><M><G><V><K><L><P><F><Q><I><S><F><T><G><S><D><W><I><V><L><I><L><A><T><I><L><F><F><Y><G><G><K><P><F><L><S><G><A><K><D><E><I><S><T><K><K><P><G><M><M><T><L><V... | Involved in copper transport.<BOP> | Q6GIX4 |
O22845 | CML5_ARATH | Protein MULTICOPY SUPPRESSORS OF SNF4 DEFICIENCY IN YEAST 3 | Arabidopsis | <M><V><R><I><F><L><L><Y><N><I><L><N><S><F><L><L><S><L><V><P><K><K><L><R><T><L><F><P><L><S><W><F><D><K><T><L><H><K><N><S><P><P><S><P><S><T><M><L><P><S><P><S><S><S><S><A><P><T><K><R><I><D><P><S><E><L><K><R><V><F><Q><M><F><D><K><N><G><D><G><R><I><T><K><E><E><L><N><D><S><L><E><N><L><G><I><Y><I><P><D><K><D><L><T><Q><M><I><H... | Potential calcium sensor.<BOP> | O22845 |
P06504 | CRYGS_BOVIN | Gamma-S-crystallin | Bos | <M><S><K><A><G><T><K><I><T><F><F><E><D><K><N><F><Q><G><R><H><Y><D><S><D><C><D><C><A><D><F><H><M><Y><L><S><R><C><N><S><I><R><V><E><G><G><T><W><A><V><Y><E><R><P><N><F><A><G><Y><M><Y><I><L><P><R><G><E><Y><P><E><Y><Q><H><W><M><G><L><N><D><R><L><S><S><C><R><A><V><H><L><S><S><G><G><Q><Y><K><L><Q><I><F><E><K><G><D><F><N><G><Q... | Crystallins are the dominant structural components of the vertebrate eye lens.<BOP> | P06504 |
Q32RG0 | RPOB_ZYGCR | Plastid-encoded RNA polymerase subunit beta | Zygnema | <M><L><S><I><N><R><N><A><G><M><F><V><L><P><D><F><K><Q><I><Q><I><D><S><F><R><H><F><L><T><D><L><L><R><L><E><L><Q><R><F><G><T><I><K><H><A><N><Q><Q><L><E><F><K><L><L><G><E><L><Y><R><L><E><I><P><K><F><N><E><R><E><A><V><Y><Q><S><A><T><Y><S><S><N><L><Y><A><P><A><Y><L><V><D><K><K><R><G><I><I><Q><K><Q><T><V><F><L><G><S><I><P><L... | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP> | Q32RG0 |
Q0SXL5 | NANM_SHIF8 | Sialic acid epimerase | Shigella | <M><N><K><T><I><M><A><L><A><I><M><M><A><S><F><A><A><N><A><S><V><L><P><E><T><P><V><P><F><K><S><G><T><G><A><I><D><N><D><T><V><Y><I><G><L><G><S><A><G><T><A><W><Y><K><L><D><T><Q><A><K><D><K><K><W><T><A><L><A><A><F><P><G><G><P><R><E><Q><A><T><S><A><F><I><D><G><N><L><Y><V><F><G><G><I><G><K><N><S><E><G><L><T><Q><V><F><N><D><V... | Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid r... | Q0SXL5 |
C4ZPX8 | PDXA_ECOBW | 4-(phosphohydroxy)-L-threonine dehydrogenase | Escherichia | <M><V><K><T><Q><R><V><V><I><T><P><G><E><P><A><G><I><G><P><D><L><V><V><Q><L><A><Q><R><E><W><P><V><E><L><V><V><C><A><D><A><T><L><L><T><N><R><A><A><M><L><G><L><P><L><T><L><R><P><Y><S><P><N><S><P><A><Q><P><Q><T><A><G><T><L><T><L><L><P><V><A><L><R><A><P><V><T><A><G><Q><L><A><V><E><N><G><H><Y><V><V><E><T><L><A><R><A><C><D><G... | Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).<BOP> | C4ZPX8 |
A6U760 | CCME_SINMW | Heme chaperone CcmE | Sinorhizobium | <M><T><R><K><Q><K><R><L><A><I><I><G><G><G><V><G><F><L><T><A><A><V><L><L><V><M><F><A><F><S><Q><A><V><A><Y><F><Y><V><P><G><D><L><T><K><A><D><V><A><P><G><T><R><I><R><L><G><G><L><V><E><A><G><S><V><K><R><G><E><G><R><T><I><T><F><K><V><T><D><T><L><A><T><V><P><V><T><Y><T><G><I><L><P><D><L><F><R><E><G><Q><G><V><V><A><E><G><A><F... | Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.<BOP> | A6U760 |
D2Y2M4 | H8A13_CYRHA | Peptide F4-27.90 | Haplopelma | <M><V><N><M><K><A><S><M><F><L><T><S><A><G><L><V><P><L><F><V><V><C><Y><A><S><E><S><E><E><K><E><F><P><K><E><M><L><S><S><I><F><A><V><D><N><D><F><K><Q><E><E><R><D><C><A><G><Y><M><R><E><C><K><E><K><L><C><C><S><G><Y><V><C><S><S><R><W><K><W><C><V><L><P><A><P><W><R><R> | Ion channel inhibitor.<BOP> | D2Y2M4 |
P0DPU3 | TX14A_SCODE | SLPTX-SSD14 subunit beta | Scolopendra | <M><G><T><S><Y><R><K><L><G><Y><V><L><F><L><M><L><G><M><I><V><E><E><G><I><A><Y><V><R><V><K><E><K><Q><S><S><P><S><F><M><G><I><Y><D><E><S><A><V><A><S><D><A><V><P><C><A><E><A><G><Q><S><M><L><R><Q><K><G><S><A><V><D><A><A><I><A><T><L><L><C><I><G><V><Y><N><P><Q><S><S><G><I><G><G><G><S><F><M><V><I><Y><D><R><S><T><R><T><P><E><V... | Dose-dependently induces human platelet aggregation on both plasma rich platelet and washed platelet (max. response at 3.2 ug/mL) and causes hemolysis against mouse and rabbit erythrocytes (35 and 65% respectively at 5 ug/mL). Does not show hemolytic activity against human erythrocytes (even at 100 ug/mL).<BOP> | P0DPU3 |
P42347 | PI3K1_SOYBN | SPI3K-5 | Glycine subgen. Soja | <M><T><G><N><E><F><R><F><F><L><S><C><D><I><S><V><P><V><T><F><R><V><E><R><L><E><G><N><L><P><L><P><N><P><K><S><P><D><L><E><T><N><A><P><T><E><N><R><T><K><E><L><F><V><E><C><A><L><Y><I><D><G><A><P><F><G><L><P><T><R><T><R><L><E><S><S><G><P><S><Y><C><W><N><E><L><I><T><L><T><T><K><Y><R><D><L><T><A><Q><S><Q><L><T><F><T><V><W><D... | Associated with membrane proliferation.<BOP> | P42347 |
P38247 | SLM4_YEAST | GSE complex subunit 1 | Saccharomyces | <M><V><M><L><H><S><K><N><V><K><G><F><L><E><N><T><L><K><P><Y><D><L><H><S><V><D><F><K><T><S><S><L><Q><S><S><M><I><I><T><A><T><N><G><G><I><L><S><Y><A><T><S><N><N><D><V><P><K><N><S><I><N><E><I><N><S><V><N><N><L><K><M><M><S><L><L><I><K><D><K><W><S><E><D><E><N><D><T><E><E><Q><H><S><N><S><C><Y><P><V><E><I><D><S><F><K><T><K><I... | Component of the GSE complex, a GTPase complex required for intracellular sorting of GAP1 out of the endosome . Component of the EGO complex, a complex involved in the regulation of microautophagy .<BOP> | P38247 |
C1A6P1 | RS12_GEMAT | 30S ribosomal protein S12 | Gemmatimonas | <M><P><T><I><N><Q><L><V><R><R><A><R><K><D><V><V><E><K><S><K><A><P><A><L><K><S><N><P><F><K><R><G><V><C><T><R><V><Y><T><T><T><P><K><K><P><N><S><A><L><R><K><V><A><R><I><R><L><T><N><Q><L><E><V><T><A><Y><I><P><G><E><G><H><N><L><Q><E><H><S><I><V><L><V><R><G><G><R><V><K><D><L><P><G><V><R><Y><H><I><V><R><G><T><L><D><A><S><G><V... | Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The com... | C1A6P1 |
A2SM29 | GLPK_METPP | Glycerokinase | Methylibium | <M><T><Y><L><L><A><L><D><Q><G><T><S><S><S><R><S><I><V><F><D><R><G><G><R><I><R><A><M><A><Q><R><E><F><R><Q><L><Y><P><Q><P><G><W><V><E><H><D><P><M><E><I><W><E><T><Q><L><A><T><A><R><E><A><L><A><Q><A><G><L><T><A><S><D><I><A><A><I><G><I><T><N><Q><R><E><T><T><L><L><W><E><R><A><S><G><R><P><I><A><N><A><I><V><W><Q><D><R><R><T><E... | Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.<BOP> | A2SM29 |
Q1IEI5 | NDK_PSEE4 | Nucleoside-2-P kinase | Pseudomonas | <M><A><V><Q><R><T><F><S><I><I><K><P><D><A><V><A><K><N><V><I><G><K><I><T><T><R><F><E><E><A><G><L><K><I><V><A><S><K><I><K><Q><L><S><K><A><E><A><E><G><F><Y><A><E><H><S><A><R><G><F><F><G><D><L><V><A><F><M><T><S><G><P><V><V><V><Q><V><L><E><G><E><N><A><I><A><L><N><R><E><L><M><G><A><T><N><P><K><E><A><A><P><G><T><I><R><A><D><F... | Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.<BOP> | Q1IEI5 |
Q0BWA2 | DCUP_GRABC | Uroporphyrinogen decarboxylase | Granulibacter | <M><N><K><P><I><L><R><V><L><R><G><E><A><L><P><V><P><P><V><W><L><M><R><Q><A><G><R><Y><L><P><E><Y><R><E><V><R><A><K><A><G><S><F><L><G><L><A><T><H><P><E><W><A><A><E><V><T><L><Q><P><I><R><R><F><G><M><D><A><A><I><L><F><S><D><I><L><M><L><P><W><A><L><G><Y><G><L><H><F><A><E><G><E><G><P><V><L><P><K><L><E><E><A><D><I><D><R><L><D... | Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.<BOP> | Q0BWA2 |
Q15X54 | RL15_PSEA6 | 50S ribosomal protein L15 | Pseudoalteromonas | <M><H><L><N><T><L><A><P><A><P><G><A><K><K><S><S><K><R><V><G><R><G><M><G><S><G><L><G><K><T><G><G><R><G><H><K><G><Q><K><S><R><S><G><G><S><V><K><P><G><F><E><G><G><Q><M><P><I><Q><R><R><L><P><K><F><G><F><T><S><R><K><S><L><V><S><D><Q><V><T><L><S><E><I><A><K><V><E><G><E><V><V><S><L><E><T><L><K><A><A><G><L><V><K><K><E><M><L><F... | Binds to the 23S rRNA.<BOP> | Q15X54 |
C5CC53 | RS17_MICLC | 30S ribosomal protein S17 | Micrococcus | <M><T><E><Q><T><P><A><V><S><E><E><R><G><Y><R><K><A><L><R><G><I><V><V><S><D><K><M><D><K><T><I><V><V><E><V><Q><D><R><K><K><H><S><L><Y><G><K><V><M><K><T><S><K><R><V><K><A><H><D><E><E><N><T><A><G><V><G><D><R><V><R><I><A><E><T><R><P><L><S><A><S><K><R><W><R><L><V><E><V><V><E><R><A><K> | One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.<BOP> | C5CC53 |
B9MBV3 | RL18_ACIET | 50S ribosomal protein L18 | Diaphorobacter | <M><L><T><K><K><E><Q><R><L><R><R><A><R><Q><T><R><I><R><I><A><Q><Q><G><V><A><R><L><T><V><N><R><T><N><L><H><I><Y><A><S><V><I><S><G><D><G><S><K><V><L><A><S><A><S><T><A><E><A><D><V><R><K><S><L><G><G><S><G><K><G><G><N><A><A><A><A><Q><I><I><G><K><R><I><A><E><K><A><K><A><A><G><V><E><K><V><A><F><D><R><A><G><F><A><Y><H><G><R><V... | This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.<BOP> | B9MBV3 |
Q28RF2 | ANMK1_JANSC | AnhMurNAc kinase 1 | unclassified Jannaschia | <M><A><G><K><E><K><A><V><W><P><P><V><W><A><A><G><A><M><S><G><T><S><F><D><G><V><D><V><A><L><L><L><T><D><G><V><R><I><E><A><F><G><D><A><R><E><V><A><Y><S><D><A><D><R><A><I><L><R><E><A><M><G><A><W><P><G><E><A><R><A><E><V><A><A><Q><V><V><E><A><A><H><I><T><A><M><V><D><L><P><D><V><A><L><L><G><F><H><G><Q><T><L><A><H><D><P><E><A... | Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall ... | Q28RF2 |
Q9ZZX1 | SCE4_YEAST | Intron-encoded endonuclease I-SceIV | Saccharomyces | <M><V><Q><R><W><L><Y><S><T><N><A><K><D><I><A><V><L><Y><F><M><L><A><I><F><S><G><M><A><G><T><A><M><S><L><I><I><R><L><E><L><A><A><P><G><S><Q><Y><L><H><G><N><S><Q><L><F><N><V><L><V><V><G><H><A><V><L><M><I><F><F><L><V><M><P><A><L><I><G><G><F><G><N><Y><L><L><P><L><M><I><G><A><T><D><T><A><F><P><R><I><N><N><I><A><F><W><V><L><P... | Mitochondrial DNA endonuclease involved in intron homing. It introduces a specific double-strand break in the DNA of the COX1 gene and thus mediates the insertion of an intron, containing its own coding sequence (group I intron), into an intronless gene. Recognizes with limited specificity and cleaves the sequence 5'-A... | Q9ZZX1 |
Q8K045 | PKN3_MOUSE | Protein-kinase C-related kinase 3 | Mus | <M><E><H><R><K><P><G><T><G><Q><R><A><P><K><D><E><K><E><M><V><R><R><A><I><Q><K><E><L><K><I><K><E><G><M><E><N><M><R><R><V><A><T><D><R><R><H><L><G><H><V><Q><Q><L><L><R><A><S><N><R><R><L><E><Q><L><H><G><E><L><R><E><L><H><A><Q><V><L><L><P><A><S><A><E><P><V><T><S><E><P><Q><P><R><A><E><Q><S><R><A><R><L><S><E><A><L><H><R><Q><L... | Contributes to invasiveness in malignant prostate cancer.<BOP> | Q8K045 |
A5WA47 | UBIB_PSEP1 | Ubiquinone biosynthesis protein UbiB | Pseudomonas | <M><K><L><L><A><V><R><R><L><F><R><I><Q><R><V><V><I><R><Y><R><L><D><D><L><L><F><D><Q><P><L><L><P><W><W><L><A><S><L><R><L><L><M><P><W><R><W><L><P><R><K><P><T><E><L><S><R><G><A><R><L><R><L><A><L><Q><D><L><G><P><I><F><I><K><F><G><Q><L><L><S><T><R><R><D><L><L><P><P><D><I><A><D><E><L><M><L><L><Q><D><R><V><P><P><F><D><P><K><K... | Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.<BOP> | A5WA47 |
B1XSC4 | MNMG_POLNS | Glucose-inhibited division protein A | Polynucleobacter | <M><R><Y><S><K><N><F><D><V><I><V><V><G><G><G><H><A><G><T><E><A><A><L><A><S><A><R><M><G><C><D><T><L><L><I><T><H><S><I><E><N><L><G><A><M><S><C><N><P><S><I><G><G><I><G><K><G><H><L><V><K><E><I><D><A><M><G><G><A><M><A><A><A><T><D><E><A><G><I><Q><F><R><I><L><N><S><S><K><G><P><A><V><R><A><T><R><A><Q><G><D><R><V><L><Y><K><A><A... | NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP> | B1XSC4 |
A0RME8 | BIOB_CAMFF | Biotin synthase | Campylobacter | <M><L><C><A><I><C><N><V><S><S><G><N><C><A><E><D><C><A><Y><C><T><Q><S><A><H><I><K><A><D><I><P><K><F><K><Q><K><N><L><E><Q><I><L><N><E><A><K><I><A><S><K><N><Y><A><L><G><F><C><L><V><T><S><G><L><G><L><D><D><K><K><L><E><F><I><C><E><A><A><T><M><L><R><K><E><T><P><N><L><M><L><I><A><C><N><G><S><A><S><Y><E><S><L><K><E><L><K><K><V... | Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.<BOP> | A0RME8 |
Q2YC67 | ILVD_NITMU | Dihydroxy-acid dehydratase | Nitrosospira | <M><S><D><N><Q><R><S><R><A><I><T><Q><G><A><E><R><T><P><N><R><A><M><L><R><A><V><G><F><S><D><N><D><F><D><K><P><I><V><G><V><A><N><G><F><S><T><I><T><P><C><N><K><G><L><N><E><L><A><L><A><A><E><Q><A><L><K><Q><A><A><A><M><P><Q><M><F><G><T><I><T><V><S><D><G><I><S><M><G><T><E><G><M><K><Y><S><L><V><S><R><E><V><I><A><D><S><I><E><T... | Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (... | Q2YC67 |
Q9HUE8 | NHAP2_PSEAE | Potassium/proton antiporter NhaP2 | Pseudomonas | <M><D><A><V><T><V><N><N><F><F><L><I><G><A><V><L><V><G><M><S><I><L><V><S><S><L><S><S><R><L><G><I><P><I><L><V><I><F><L><A><V><G><M><I><A><G><N><D><G><V><G><G><I><V><F><D><N><Y><P><M><A><Y><L><V><G><N><L><A><L><A><V><I><L><L><D><G><G><L><R><T><R><V><S><S><F><R><V><A><L><W><P><A><L><S><L><A><T><L><G><V><L><V><T><T><G><L><T... | K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.<BOP> | Q9HUE8 |
A0QGA4 | KATG_MYCA1 | Peroxidase/catalase | Mycobacterium avium complex (MAC) | <M><S><S><D><T><S><A><S><R><P><P><Q><P><D><T><G><T><A><S><K><S><E><S><E><N><P><A><I><P><S><P><H><P><K><S><N><A><P><L><T><N><R><D><W><W><P><N><Q><I><D><V><S><R><L><H><P><H><V><A><E><A><N><P><L><G><E><D><F><D><Y><A><E><E><F><A><K><L><D><V><E><A><L><K><A><D><V><I><S><V><M><T><T><S><Q><D><W><W><P><A><D><Y><G><H><Y><G><G><L... | Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.<BOP> | A0QGA4 |
B1AJM6 | DEOC_UREP2 | Phosphodeoxyriboaldolase | Ureaplasma | <M><N><K><Y><N><I><Y><V><D><H><T><L><L><K><A><D><A><S><L><E><E><I><H><K><L><C><E><E><A><E><E><N><E><F><Y><S><V><C><I><N><P><C><F><V><K><V><A><K><H><Y><L><L><E><T><S><V><K><I><C><T><V><I><G><F><P><L><G><A><N><T><I><E><T><K><V><F><E><T><K><N><A><I><D><L><G><A><D><E><I><D><M><V><I><N><I><N><Q><L><I><N><G><N><R><E><Y><C><L... | Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.<BOP> | B1AJM6 |
Q1C5J4 | EX7L_YERPA | Exodeoxyribonuclease VII large subunit | Yersinia | <M><S><Q><S><S><A><S><S><I><F><T><V><S><R><L><N><Q><T><V><R><E><L><L><E><R><E><M><G><Q><I><W><L><T><A><E><I><S><N><F><S><Q><P><A><S><G><H><W><Y><F><T><L><K><D><D><R><A><Q><V><R><C><A><M><F><R><N><S><N><R><R><T><T><F><R><P><Q><N><G><Q><Q><V><L><V><R><A><S><I><T><L><Y><E><P><R><G><D><Y><Q><L><I><A><E><S><M><Q><P><A><G><D... | Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.<BOP> | Q1C5J4 |
Q16AP3 | RL19_ROSDO | 50S ribosomal protein L19 | Roseobacter | <M><D><L><I><A><Q><I><E><A><E><Q><I><A><A><L><G><K><D><I><P><D><F><R><A><G><D><T><V><R><V><G><F><K><V><T><E><G><T><R><T><R><V><Q><N><Y><E><G><V><C><I><A><R><N><N><G><H><G><I><A><G><S><F><T><V><R><K><I><S><F><G><E><G><V><E><R><V><F><P><L><H><S><T><N><I><E><S><I><T><V><V><R><R><G><R><V><R><R><A><K><L><Y><Y><L><R><S><R><R... | This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.<BOP> | Q16AP3 |
Q06SJ5 | RR19_STIHE | 30S ribosomal protein S19, chloroplastic | Stigeoclonium | <M><S><R><S><L><K><K><G><P><F><V><A><D><H><L><L><K><K><I><E><K><L><N><I><K><G><I><Q><K><V><I><V><T><W><S><R><S><S><T><I><V><P><I><M><I><G><H><T><V><A><V><H><N><G><R><E><H><I><P><V><F><I><T><D><K><M><V><G><H><K><L><G><E><F><A><L><T><R><T><F><K><T><H><T><K><K><V><N><K><K><T><K><R> | Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.<BOP> | Q06SJ5 |
A4JGE0 | LEU1_BURVG | Alpha-isopropylmalate synthase | Burkholderia cepacia complex | <M><T><D><K><L><I><I><F><D><T><T><L><R><D><G><E><Q><S><P><G><A><S><M><T><K><E><E><K><I><R><I><A><K><H><L><E><R><M><K><V><D><V><I><E><A><G><F><A><A><S><S><N><G><D><F><D><A><I><H><T><I><A><G><L><V><K><D><S><T><I><C><S><L><A><R><A><N><D><K><D><I><Q><R><A><A><D><A><L><K><P><A><S><S><A><R><I><H><T><F><I><A><T><S><P><L><H><M... | Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).<BOP> | A4JGE0 |
P86240 | FAHD2_MESAU | Fumarylacetoacetate hydrolase domain-containing protein 2A | Mesocricetus | <R><A><L><A><T><Q><L><P><V><I><P><R><S><Q><V><T><F><L><A><P><V><T><R><P><E><K> | May have hydrolase activity.<BOP> | P86240 |
C1GTX5 | GATB_PARBA | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial | Paracoccidioides | <M><I><R><Q><C><L><S><R><R><A><A><Y><P><C><Y><R><I><V><A><G><G><T><E><P><T><G><C><L><Y><P><Q><S><C><R><I><S><R><R><G><R><D><W><S><S><T><S><R><R><A><I><D><T><Q><T><S><G><A><S><N><G><A><D><Y><V><P><L><R><Q><Q><L><K><E><Q><A><R><A><K><R><A><A><K><R><K><G><E><V><S><P><P><E><H><E><D><W><E><L><T><V><G><I><E><I><H><A><Q><L><D... | Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).<BOP> | C1GTX5 |
Q8CI85 | CAH12_MOUSE | Carbonic anhydrase XII | Mus | <M><P><H><R><S><L><R><A><T><V><V><L><L><L><V><I><L><K><K><Q><P><S><S><S><A><P><L><N><G><S><K><W><T><Y><V><G><P><A><G><E><K><N><W><S><K><K><Y><P><S><C><G><G><L><L><Q><S><P><I><D><L><H><S><D><I><L><Q><Y><D><A><S><L><A><P><L><Q><F><Q><G><Y><N><V><S><V><E><K><L><L><N><L><T><N><D><G><H><S><V><R><L><N><L><N><S><D><M><Y><I><Q... | Reversible hydration of carbon dioxide.<BOP> | Q8CI85 |
B5E964 | NUOK1_CITBB | NDH-1 subunit K 1 | Citrifermentans | <M><T><I><P><L><Y><E><V><L><I><L><A><S><I><L><F><A><M><G><L><A><C><V><V><A><W><R><A><N><V><I><M><M><L><I><G><I><E><I><M><L><N><A><V><M><L><T><F><V><G><G><S><A><H><W><G><I><A><E><G><Q><V><F><S><L><M><I><M><A><L><T><S><A><E><V><S><L><A><L><A><M><V><A><Y><L><H><R><R><K><Q><S><V><D><T><D><D><F><S><S><M><K><G> | NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are t... | B5E964 |
Q48QH6 | HEM6_PSE14 | Oxygen-dependent coproporphyrinogen-III oxidase | Pseudomonas | <M><S><T><R><T><E><A><V><K><A><Y><L><L><D><L><Q><D><R><I><C><T><A><L><E><Q><E><D><G><N><A><H><F><V><E><D><A><W><T><R><P><A><G><G><G><G><R><T><R><V><I><E><N><G><A><V><I><E><K><G><G><V><N><F><S><H><V><F><G><S><N><L><P><P><S><A><S><A><H><R><P><E><L><A><G><R><G><F><E><A><L><G><V><S><L><V><I><H><P><H><N><P><H><V><P><T><S><H... | Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.<BOP> | Q48QH6 |
Q9K4B1 | HISN_STRCO | Histidinol-phosphate phosphatase | Streptomyces albidoflavus group | <M><P><D><Y><L><D><D><L><R><L><A><H><V><L><A><D><A><A><D><A><A><T><M><D><R><F><K><A><L><D><L><K><V><E><T><K><P><D><M><T><P><V><S><E><A><D><K><A><A><E><E><L><I><R><G><H><L><S><R><A><R><P><R><D><S><V><H><G><E><E><F><G><V><A><G><T><G><P><R><R><W><V><I><D><P><I><D><G><T><K><N><Y><V><R><G><V><P><V><W><A><T><L><I><A><L><M><E... | Catalyzes the dephosphorylation of histidinol-phosphate to histidinol, the direct precursor of histidine.<BOP> | Q9K4B1 |
Q6IRU2 | TPM4_MOUSE | Tropomyosin-4 | Mus | <M><A><G><L><N><S><L><E><A><V><K><R><K><I><Q><A><L><Q><Q><Q><A><D><D><A><E><D><R><A><Q><G><L><Q><R><E><L><D><G><E><R><E><R><R><E><K><A><E><G><D><A><A><A><L><N><R><R><I><Q><L><L><E><E><E><L><D><R><A><Q><E><Q><L><A><T><A><L><Q><N><L><E><E><A><E><K><A><A><D><E><S><E><R><G><M><K><V><I><E><N><R><A><M><K><D><E><E><K><M><E><I... | Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing c... | Q6IRU2 |
Q0VCP2 | PX11A_BOVIN | Peroxisomal biogenesis factor 11A | Bos | <M><D><A><F><I><R><F><T><N><Q><T><Q><G><R><D><R><L><F><R><A><T><Q><Y><T><C><M><L><L><R><Y><L><L><E><P><K><A><D><N><E><K><V><V><M><K><L><K><K><L><E><S><S><V><S><T><G><R><K><W><F><R><L><G><N><V><V><H><A><L><Q><A><T><Q><Q><S><V><R><A><T><D><L><V><P><R><I><C><L><T><L><A><S><L><N><R><V><I><Y><F><I><C><D><T><V><L><F><V><R><S... | May be involved in peroxisomal proliferation and may regulate peroxisomes division. May mediate binding of coatomer proteins to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface.<BOP> | Q0VCP2 |
Q8PQ74 | HGD_XANAC | Homogentisicase | Xanthomonas | <M><I><Q><R><D><P><N><L><L><L><S><W><R><A><D><Q><H><P><D><A><P><M><H><N><D><Q><R><Y><M><T><G><F><G><N><E><F><A><T><E><A><V><A><G><S><L><P><I><G><Q><N><S><P><Q><R><V><A><H><G><L><Y><A><E><Q><L><S><G><T><A><F><T><A><P><R><G><Q><N><R><R><S><W><L><Y><R><I><R><P><A><A><V><H><G><S><F><S><L><V><E><Q><S><H><F><H><N><D><F><G><A... | Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.<BOP> | Q8PQ74 |
P85221 | HLY3C_STACC | Hemolysin H3C | Staphylococcus | <M><S><D><F><V><N><A><I><S><E><A><V><K><A><G><L><S><A><D><W><V><T><M><G><T><S><I><A><D><A><L><A><K><G><A><D><F><I><L><G><F><F><N> | Virulence factor. Causes hemolysis of erythrocytes from sheep (HD(50)=2.63 mM), rabbit (HD(50)=2.37 mM), guinea pig (HD(50)=1.98 mM), dog (HD(50)=1.02 mM) and human (HD(50)=2.07 mM). Acts synergistically with beta-hemolysins from S.aureus ATCC 25923. Cytotoxic towards human dermal fibroblasts.<BOP> | P85221 |
Q9A3G7 | RUVA_CAUVC | Holliday junction ATP-dependent DNA helicase RuvA | Caulobacter | <M><I><G><R><L><R><G><A><V><A><E><V><G><E><E><E><A><L><I><D><V><M><G><V><G><Y><L><V><R><C><G><H><R><T><L><Q><R><L><P><A><L><G><E><E><T><L><L><H><I><E><S><Q><W><S><E><S><A><G><L><R><L><Y><G><F><L><T><R><E><D><R><R><A><F><V><L><L><Q><A><I><Q><G><V><G><P><K><A><A><M><A><V><L><D><V><L><S><P><A><E><L><A><S><A><V><A><R><E><D... | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA... | Q9A3G7 |
Q38WT6 | RNZ_LATSS | tRNase Z | Latilactobacillus | <M><E><L><E><F><L><G><T><G><A><G><V><P><A><R><Q><R><N><V><T><S><I><A><L><K><L><L><D><E><R><N><E><V><W><L><F><D><V><G><E><A><T><Q><H><Q><I><L><K><T><T><L><K><P><R><K><V><K><K><I><F><L><T><H><L><H><G><D><H><L><F><G><L><P><G><F><L><S><S><R><S><F><Q><G><G><D><E><P><L><T><I><Y><G><P><K><G><T><E><E><Y><V><R><T><S><L><K><L><S... | Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.<BOP> | Q38WT6 |
Q5E6U2 | MIAB_ALIF1 | tRNA-i(6)A37 methylthiotransferase | Aliivibrio | <M><T><K><K><L><L><I><K><T><W><G><C><Q><M><N><E><Y><D><S><S><K><M><A><D><L><L><G><A><A><N><G><Y><E><L><T><E><E><P><T><E><A><D><V><L><L><L><N><T><C><S><I><R><E><K><A><Q><E><K><V><F><H><Q><L><G><R><W><K><N><L><K><D><K><K><P><D><L><V><I><G><V><G><G><C><V><A><T><Q><E><G><D><H><I><R><Q><R><A><P><Y><V><D><V><I><F><G><P><Q><T... | Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.<BOP> | Q5E6U2 |
Q5HM21 | IF1_STAEQ | Translation initiation factor IF-1 | Staphylococcus | <M><A><K><Q><D><V><I><E><L><E><G><T><V><L><D><T><L><P><N><A><M><F><K><V><E><L><E><N><G><H><E><I><L><A><H><V><S><G><K><I><R><M><N><Y><I><R><I><L><P><G><D><K><V><T><V><E><M><S><P><Y><D><L><S><R><G><R><I><T><Y><R><Y><K> | One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-... | Q5HM21 |
Q7VS51 | GCS2_BORPE | Gamma-glutamylcysteine synthetase 2 | Bordetella | <M><E><Q><I><P><F><V><S><S><A><P><N><T><L><G><I><E><L><E><L><Q><L><V><D><P><R><S><F><D><L><A><A><A><S><D><E><L><L><A><Q><L><A><N><H><P><I><A><D><R><V><K><P><E><I><T><R><S><M><I><E><L><N><S><S><V><H><E><H><P><A><G><L><L><A><E><M><R><E><M><R><D><V><L><C><E><A><A><D><A><V><G><V><G><V><T><G><G><G><A><H><P><F><M><R><W><Q><D... | ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.<BOP> | Q7VS51 |
Q6TYI6 | TREM1_PIG | Triggering receptor expressed on myeloid cells 1 | Sus | <M><R><S><A><R><L><G><R><L><L><W><M><L><F><I><T><E><I><Q><A><A><T><E><L><P><E><E><K><Y><I><L><A><E><G><E><T><L><N><V><N><C><P><V><T><V><G><V><Y><S><N><S><R><K><A><W><Q><K><L><N><R><N><G><K><F><Q><T><L><A><I><T><E><R><V><S><G><Q><V><S><K><V><Q><V><G><K><I><F><L><T><D><E><P><S><E><G><M><L><H><V><Q><M><T><N><V><Q><A><E><D... | Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses. Upon activation by various ligands such as PGLYRP1, HMGB1 or HSP70, multimerizes and forms a complex with transmembrane adapter TYROBP/DAP12. In turn, initiates a SYK-mediated cascade of tyrosine phosp... | Q6TYI6 |
Q88EW5 | CHEB1_PSEPK | Protein-glutamate methylesterase/protein-glutamine glutaminase of group 1 operon | Pseudomonas | <M><A><V><K><V><L><V><V><D><D><S><G><F><F><R><R><R><V><S><E><I><L><S><A><D><P><T><I><Q><V><V><G><T><A><T><N><G><K><E><A><I><D><Q><A><L><A><L><K><P><D><V><I><T><M><D><Y><E><M><P><M><M><D><G><I><T><A><V><R><H><I><M><Q><R><C><P><T><P><V><L><M><F><S><S><L><T><H><E><G><A><R><V><T><L><D><A><L><D><A><G><A><V><D><Y><L><P><K><N... | Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deam... | Q88EW5 |
A7H1U7 | MOAC_CAMJD | Molybdenum cofactor biosynthesis protein C | Campylobacter | <M><K><L><S><H><L><D><E><K><N><H><P><K><M><V><D><V><S><D><K><N><I><T><S><R><M><A><T><A><S><G><V><I><Y><M><S><Q><E><A><F><D><V><I><K><N><N><T><A><K><K><G><P><V><L><Q><T><A><I><V><A><A><I><M><G><A><K><K><T><S><E><I><I><P><M><C><H><P><L><M><L><S><K><I><E><T><D><I><V><E><F><V><K><E><C><A><F><K><L><I><V><T><V><K><C><E><G><K... | Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).<BOP> | A7H1U7 |
Q48BF0 | RNPA_PSE14 | Protein C5 | Pseudomonas | <M><S><R><D><F><S><R><E><K><R><L><L><T><P><R><H><F><K><A><V><F><D><S><P><T><G><K><V><P><G><K><N><L><L><L><L><A><R><N><N><D><L><D><H><P><R><L><G><L><V><I><G><K><K><S><V><K><L><S><V><E><R><N><R><L><K><R><L><M><R><E><S><F><R><Q><H><Q><D><S><L><V><G><W><D><I><V><I><V><A><R><K><G><L><G><D><V><E><N><P><E><L><I><Q><Y><F><G><K... | RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the riboz... | Q48BF0 |
Q64433 | CH10_MOUSE | Chaperonin 10 | Mus | <M><A><G><Q><A><F><R><K><F><L><P><L><F><D><R><V><L><V><E><R><S><A><A><E><T><V><T><K><G><G><I><M><L><P><E><K><S><Q><G><K><V><L><Q><A><T><V><V><A><V><G><S><G><G><K><G><K><S><G><E><I><E><P><V><S><V><K><V><G><D><K><V><L><L><P><E><Y><G><G><T><K><V><V><L><D><D><K><D><Y><F><L><F><R><D><S><D><I><L><G><K><Y><V><D> | Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matri... | Q64433 |
P53095 | DSD1_YEAST | D-serine deaminase | Saccharomyces | <M><S><D><V><L><S><Q><Y><K><G><C><S><V><R><D><L><P><T><P><N><F><V><I><N><E><E><K><F><D><K><N><C><T><T><M><L><N><N><V><E><K><L><S><Q><E><C><G><V><P><I><K><F><R><A><H><V><K><T><H><K><T><A><K><G><T><L><K><Q><L><G><H><G><L><P><L><A><K><R><T><T><R><A><I><L><V><S><T><L><K><E><A><E><E><L><L><N><Y><Q><D><R><Q><C><S><D><Y><I><D... | Converts specifically D-serine to pyruvate and ammonia. May play a role in D-serine detoxification.<BOP> | P53095 |
P83249 | TOP2B_OXYTA | Oxyopinin-2b | Oxyopes | <G><K><F><S><G><F><A><K><I><L><K><S><I><A><K><F><F><K><G><V><G><K><V><R><K><Q><F><K><E><A><S><D><L><D><K><N><Q> | Disrupts biological membranes, particularly those rich in phosphocholine. Has antimicrobial activity against Gram-negative bacterium E.coli, Gram-positive bacteria B.subtilis and S.aureus, and hemolytic activity against sheep, pig and guinea pig red blood cells. Has insecticidal activity against S.frugiperda ovarian ce... | P83249 |
C5DSA7 | MTC6_ZYGRC | Maintenance of telomere capping protein 6 | Zygosaccharomyces | <M><N><G><L><L><L><I><L><L><V><Y><I><T><V><W><R><P><R><P><C><Q><C><I><Q><E><R><D><I><Q><R><D><V><E><D><L><P><S><V><S><Y><Q><V><Q><Y><G><I><R><S><Q><R><D><L><M><A><N><V><P><I><D><Q><V><P><M><I><G><V><N><I><F><D><A><F><L><K><N><G><R><N><N><D><S><R><A><L><L><S><F><M><E><L><M><Q><H><G><V><Q><S><F><T><V><D><L><E><P><R><N><S... | May be involved in telomere capping.<BOP> | C5DSA7 |
Q6P0C6 | LHPL2_DANRE | LHFPL tetraspan subfamily member 2a protein | Danio | <M><C><H><V><I><V><T><C><R><S><M><L><W><T><L><L><S><I><V><A><A><F><S><E><L><I><A><F><L><S><T><D><W><L><V><G><F><P><R><A><P><D><A><G><F><S><P><L><G><A><T><A><A><G><E><A><Y><R><P><T><L><G><I><Y><G><R><C><I><R><V><P><H><Y><R><R><G><V><L><C><G><P><Y><A><V><H><F><G><E><I><A><S><G><F><W><Q><A><T><A><I><F><L><A><A><G><I><L><L... | Plays a role in fertility. Involved in distal reproductive tract development.<BOP> | Q6P0C6 |
Q54UT2 | DGK_DICDI | DddGK | Dictyostelium | <M><F><R><R><S><L><M><F><M><I><S><N><N><K><N><T><N><M><V><S><S><I><N><T><T><N><K><V><N><N><F><S><K><I><I><I><L><E><G><N><I><S><A><G><K><T><Y><L><S><S><K><L><G><D><L><L><G><Y><K><V><F><L><E><P><T><A><T><N><P><Y><L><S><L><F><Y><K><E><P><S><K><Y><A><L><I><M><Q><K><W><L><L><N><Q><R><Y><N><T><F><L><N><A><L><Q><Y><S><L><E><N... | Purine-specific deoxyribonucleoside kinase that phosphorylates preferentially deoxyguanosine, as part of the deoxyribonucleotide salvage pathway.<BOP> | Q54UT2 |
Q0AUL1 | ECFA_SYNWW | Energy-coupling factor transporter ATP-binding protein EcfA | Syntrophomonas | <M><I><S><I><R><D><L><T><Y><F><Y><P><E><E><D><L><P><A><L><K><N><I><S><L><D><I><R><E><N><E><F><L><V><I><L><G><R><N><G><S><G><K><S><T><L><A><R><L><L><N><G><L><L><L><P><S><Q><G><K><V><E><V><D><G><W><N><T><A><D><A><N><Q><I><Q><L><I><R><Q><R><V><G><L><L><F><S><N><P><D><N><Q><L><I><S><N><Q><V><E><E><D><V><A><F><G><P><E><N><L... | ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.<BOP> | Q0AUL1 |
Q9FLV0 | DMR6_ARATH | Salicylate 3-hydroxylase DMR6 | Arabidopsis | <M><A><A><K><L><I><S><T><G><F><R><H><T><T><L><P><E><N><Y><V><R><P><I><S><D><R><P><R><L><S><E><V><S><Q><L><E><D><F><P><L><I><D><L><S><S><T><D><R><S><F><L><I><Q><Q><I><H><Q><A><C><A><R><F><G><F><F><Q><V><I><N><H><G><V><N><K><Q><I><I><D><E><M><V><S><V><A><R><E><F><F><S><M><S><M><E><E><K><M><K><L><Y><S><D><D><P><T><K><T><T... | (Microbial infection) Required for susceptibility to the oomycete Phytophthora capsici.<BOP> | Q9FLV0 |
Q9TYM6 | SHQ1_CAEEL | Protein SHQ1 homolog | Caenorhabditis | <M><L><T><P><V><F><W><I><T><Q><D><D><D><A><L><L><I><R><I><R><A><P><H><G><N><I><A><E><L><D><Y><D><H><G><D><Y><M><F><V><F><T><C><P><P><Y><F><L><R><L><H><F><K><Q><M><V><E><E><Y><G><S><G><N><G><S><V><E><W><K><S><D><E><G><E><F><H><I><K><V><P><K><M><H><K><K><E><H><F><S><N><L><D><M><I><T><E><L><L><T><P><S><T><T><H><H><Q><P><H... | Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs).<BOP> | Q9TYM6 |
B5DGM7 | ALDOA_SALSA | Muscle-type aldolase | Salmo | <M><P><H><A><F><P><F><L><T><P><D><Q><K><K><E><L><S><D><I><A><L><K><I><V><A><K><G><K><G><I><L><A><A><D><E><S><T><G><S><V><A><K><R><F><Q><S><I><N><T><E><N><T><E><E><N><R><R><L><Y><R><Q><L><L><F><T><A><D><D><R><A><G><P><C><I><G><G><V><I><F><F><H><E><T><L><Y><Q><K><T><D><A><G><K><T><F><P><E><H><V><K><S><R><G><W><V><V><G><I... | Plays a key role in glycolysis and gluconeogenesis.<BOP> | B5DGM7 |
A3NPW9 | RNPA_BURP0 | Protein C5 | pseudomallei group | <M><Q><A><S><A><A><F><P><K><A><A><R><L><L><K><T><D><E><F><S><S><V><F><R><L><R><P><W><R><R><T><A><H><F><V><I><Y><G><K><P><T><G><R><D><A><R><L><G><L><V><I><G><K><K><Y><A><A><R><A><V><T><R><N><L><V><K><R><L><A><R><E><A><F><R><T><R><R><A><E><F><A><G><W><D><I><L><L><R><L><H><A><R><F><D><K><K><A><M><P><S><A><A><S><A><P><L><A... | RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the riboz... | A3NPW9 |
Q8UEH1 | GLMS_AGRFC | L-glutamine--D-fructose-6-phosphate amidotransferase | Agrobacterium tumefaciens complex | <M><C><G><I><V><G><I><V><G><T><Q><P><V><A><E><R><L><V><D><A><L><K><R><L><E><Y><R><G><Y><D><S><A><G><V><A><T><I><D><N><G><A><M><D><R><R><R><A><E><G><K><L><F><N><L><E><K><L><V><S><E><K><P><L><P><G><V><V><G><I><A><H><T><R><W><A><T><H><G><V><P><N><E><I><N><A><H><P><H><F><V><D><G><V><A><V><V><H><N><G><I><I><E><N><F><S><E><L... | Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.<BOP> | Q8UEH1 |
C0Q1W8 | FPG_SALPC | DNA-(apurinic or apyrimidinic site) lyase MutM | Salmonella | <M><P><E><L><P><E><V><E><T><S><R><R><G><I><E><P><H><L><V><G><A><T><I><L><H><A><H><I><R><N><G><R><L><R><W><P><V><S><D><E><I><Y><R><L><S><D><T><P><V><L><S><V><Q><R><R><A><K><Y><L><L><L><E><L><P><D><G><W><I><I><I><H><L><G><M><S><G><S><L><R><I><L><P><E><A><L><P><A><E><K><H><D><H><V><D><L><V><M><S><N><G><K><I><L><R><Y><T><D... | Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. ... | C0Q1W8 |
Q9H8P0 | PORED_HUMAN | Steroid 5-alpha-reductase 3 | Homo | <M><A><P><W><A><E><A><E><H><S><A><L><N><P><L><R><A><V><W><L><T><L><T><A><A><F><L><L><T><L><L><L><Q><L><L><P><P><G><L><L><P><G><C><A><I><F><Q><D><L><I><R><Y><G><K><T><K><C><G><E><P><S><R><P><A><A><C><R><A><F><D><V><P><K><R><Y><F><S><H><F><Y><I><I><S><V><L><W><N><G><F><L><L><W><C><L><T><Q><S><L><F><L><G><A><P><F><P><S><W... | Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol . Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation . Acts as a polyprenol reductase that promotes the r... | Q9H8P0 |
Q9TZ64 | KLF1_CAEEL | Kruppel-like factor 1 | Caenorhabditis | <M><T><S><S><S><I><N><A><T><S><S><R><E><P><L><I><H><I><P><N><K><P><S><L><S><I><D><P><L><A><R><A><D><R><S><V><H><L><S><P><S><F><F><Q><P><G><L><S><S><I><S><S><E><N><D><D><A><E><Q><R><I><H><E><A><T><R><S><F><N><Q><F><G><H><Q><F><Y><E><S><I><R><E><L><S><E><S><T><S><A><Y><E><R><L><K><A><N><A><L><R><R><K><L><E><N><T><F><G><N... | Transcription factor which modulates genes involved in lipid metabolism and the phase I detoxification pathway, including cytochrome P450 oxidases . Required for diet restriction- and mitochondrial dysfunction-mediated lifespan extension, perhaps acting in a ubiquitination-dependent manner . Involved in the response to... | Q9TZ64 |
P35576 | G6PC1_MOUSE | Glucose-6-phosphatase | Mus | <M><E><E><G><M><N><I><L><H><D><F><G><I><Q><S><T><R><Y><L><Q><V><N><Y><Q><D><S><Q><D><W><F><I><L><V><S><V><I><A><D><L><R><N><A><F><Y><V><L><F><P><I><W><F><H><L><K><E><T><V><G><I><N><L><L><W><V><A><V><V><G><D><W><F><N><L><V><F><K><W><I><L><F><G><Q><R><P><Y><W><W><V><L><D><T><D><Y><Y><S><N><S><S><V><P><I><I><K><Q><F><P><V... | Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. Forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production in the terminal step of glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.<... | P35576 |
Q8FT38 | PYRR_COREF | Uracil phosphoribosyltransferase | Corynebacterium | <M><S><E><R><R><N><T><V><V><E><L><L><G><E><N><D><V><S><R><T><V><A><R><I><A><H><Q><I><I><E><K><T><A><L><D><S><E><G><A><D><R><V><M><L><L><G><I><P><S><G><G><V><P><L><A><E><R><L><A><A><K><I><E><E><F><S><G><V><R><V><D><T><G><A><I><D><I><T><L><Y><R><D><D><L><R><N><K><P><H><R><A><L><Q><P><T><S><I><P><S><G><G><I><D><K><T><T><V... | Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.<BOP> | Q8FT38 |
Q007T0 | SDHB_PIG | Iron-sulfur subunit of complex II | Sus | <M><A><A><V><V><A><V><S><L><K><R><W><F><P><A><T><T><L><G><G><A><C><L><Q><A><C><R><G><A><Q><T><A><A><A><T><A><P><R><I><K><K><F><A><I><Y><R><W><D><P><D><K><T><G><D><K><P><H><M><Q><T><Y><E><I><D><L><N><N><C><G><P><M><V><L><D><A><L><I><K><I><K><N><E><I><D><S><T><L><T><F><R><R><S><C><R><E><G><I><C><G><S><C><A><M><N><I><N><G... | Iron-sulfur protein (IP) subunit of the succinate dehydrogenase complex (mitochondrial respiratory chain complex II), responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).<BOP> | Q007T0 |
B3CQ33 | OBG_ORITI | GTP-binding protein Obg | Orientia | <M><Q><F><I><D><E><A><K><I><F><I><K><G><G><N><G><G><D><G><C><V><S><F><R><R><E><K><F><V><P><N><G><G><P><D><G><G><N><G><G><R><G><G><D><I><I><F><I><G><D><R><H><L><N><T><L><I><N><F><K><F><K><Q><H><F><L><A><Q><N><G><R><A><G><A><G><N><N><R><T><G><K><S><G><Q><N><L><V><L><K><V><P><V><G><T><Q><I><L><S><N><N><K><E><H><V><I><F><D... | An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B... | B3CQ33 |
P16141 | CP52D_CANMA | Cytochrome P450-CM2 | Candida | <M><P><V><S><F><V><H><N><V><L><E><V><V><T><P><Y><V><E><Y><Y><Q><E><N><L><T><K><W><Y><I><L><I><P><T><I><L><L><T><L><N><F><L><S><I><L><H><T><K><Y><L><E><Y><K><F><N><A><K><P><L><T><N><F><A><Q><D><Y><S><F><G><V><I><T><P><L><M><L><M><Y><F><K><W><H><G><T><V><M><E><F><A><C><N><V><W><N><N><K><F><L><V><L><N><G><N><V><R><T><V><G... | Together with an NADPH cytochrome P450 the enzyme system catalyzes the terminal hydroxylation as the first step in the assimilation of alkanes and fatty acids.<BOP> | P16141 |
G5EBU3 | MMPC_CAEEL | Zinc metalloprotease 3 | Caenorhabditis | <M><R><L><I><Y><V><I><A><I><L><L><V><S><T><C><Q><A><G><F><F><S><S><L><V><S><R><F><T><G><G><G><N><S><S><P><S><S><S><S><S><S><S><S><F><S><N><S><R><K><P><S><L><S><D><E><K><A><R><S><Y><L><Q><T><F><G><Y><V><P><P><S><N><S><L><Q><S><R><N><G><M><A><G><D><I><Q><S><A><E><Q><V><F><K><S><A><I><R><K><F><Q><E><F><A><G><I><A><K><T><G... | Metalloproteinase.<BOP> | G5EBU3 |
P81909 | OR22A_DROME | Odorant receptor 22a | Sophophora | <M><L><S><K><F><F><P><H><I><K><E><K><P><L><S><E><R><V><K><S><R><D><A><F><I><Y><L><D><R><V><M><W><S><F><G><W><T><E><P><E><N><K><R><W><I><L><P><Y><K><L><W><L><A><F><V><N><I><V><M><L><I><L><L><P><I><S><I><S><I><E><Y><L><H><R><F><K><T><F><S><A><G><E><F><L><S><S><L><E><I><G><V><N><M><Y><G><S><S><F><K><C><A><F><T><L><I><G><F... | Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates. The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration. Involved in the behavioral responses ethyl butyrate and to esters in more general. Complexes wi... | P81909 |
B0C915 | MURD_ACAM1 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase | Acaryochloris | <M><P><A><V><H><I><I><G><L><G><R><S><G><I><A><A><A><R><L><L><R><R><E><G><W><Q><V><S><V><G><D><A><G><H><S><E><G><L><V><A><T><Q><K><T><L><A><A><E><G><I><P><V><H><L><N><L><K><F><S><L><S><A><L><A><E><L><S><L><D><R><P><D><R><I><V><V><S><P><G><V><P><W><Q><L><P><A><L><E><E><A><R><S><Q><G><I><E><T><F><G><E><L><E><L><A><W><R><S... | Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).<BOP> | B0C915 |
Q6LUL5 | RS20_PHOPR | 30S ribosomal protein S20 | Photobacterium | <M><A><N><I><K><S><A><K><K><R><A><I><T><S><E><K><R><R><Q><H><N><A><S><R><R><S><M><M><R><T><F><F><K><K><V><I><A><A><I><E><A><G><E><K><E><N><A><T><K><A><F><A><D><M><Q><P><V><L><D><R><M><A><T><K><G><L><I><H><K><N><K><A><A><R><Q><K><A><R><L><T><A><K><I><K><A><L> | Binds directly to 16S ribosomal RNA.<BOP> | Q6LUL5 |
P46244 | SYT_BUCAP | Threonyl-tRNA synthetase | Buchnera | <M><P><V><I><R><F><C><D><G><S><Q><Q><V><Y><K><H><S><V><S><L><R><E><I><I><E><N><K><K><P><N><I><I><R><S><L><I><A><I><S><V><N><N><S><F><S><N><F><N><T><L><I><T><E><D><S><S><I><S><F><I><S><K><K><D><C><E><A><L><N><I><I><R><Y><S><C><I><Q><L><L><N><Y><A><A><K><K><T><W><P><S><C><K><I><G><E><S><E><I><T><K><S><G><F><Y><C><D><I><D... | Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).<BOP> | P46244 |
P19355 | GUX1_HYPRU | Exoglucanase I | Trichoderma | <M><Y><Q><K><L><A><L><I><S><A><F><L><A><T><A><R><A><Q><S><A><C><T><L><Q><A><E><T><H><P><P><L><T><W><Q><K><C><S><S><G><G><T><C><T><Q><Q><T><G><S><V><V><I><D><A><N><W><R><W><T><H><A><T><N><S><S><T><N><C><Y><D><G><N><T><W><S><S><T><L><C><P><D><N><E><T><C><A><K><N><C><C><L><D><G><A><A><Y><A><S><T><Y><G><V><T><T><S><A><D><S... | The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases whic... | P19355 |
B3QSB4 | PANC_CHLT3 | Pantoate-activating enzyme | Chloroherpeton | <M><K><I><I><E><T><V><S><E><M><Q><H><F><S><E><S><L><R><I><A><E><K><R><L><G><V><V><P><T><M><G><A><L><H><D><G><H><L><S><L><V><K><L><A><L><K><H><A><D><V><A><I><M><T><I><F><V><N><P><L><Q><F><G><P><S><E><D><F><A><K><Y><P><R><T><F><E><R><D><A><M><L><A><E><K><A><G><V><S><C><I><F><A><P><T><P><E><T><L><Y><P><S><G><F><Q><T><H><V... | Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<BOP> | B3QSB4 |
P81508 | SLA_CROHD | Snaclec CHH-B subunit alpha | Crotalus | <D><L><E><C><P><S><G><W><S><S><Y><D><R><Y><C><Y><K><P><F><K><Q><E><M><T><W><A><D><A><E><R><F><C><S><E><Q><A><K><G><R><H><L><L><S><V><E><T><A><L><E><A><S><F><V><D><N><V><L><Y><A><N><K><E><Y><L><T><R><Y><I><W><I><G><L><R><V><Q><N><K><G><Q><P><C><S><S><I><Y><S><E><N><L><V><D><P><F><D><C><F><M><V><S><R><D><T><R><L><R><E><W... | Binds to the subunit GPIbalpha (GP1BA) of the platelet GPIb/V/IX receptor system. It inhibits ristocetin- and vWF-induced platelet aggregation in platelet-rich plasma by inhibiting the binding of vWF to GPIbalpha.<BOP> | P81508 |
A5IJQ9 | SYP_THEP1 | Prolyl-tRNA synthetase | Thermotoga | <M><R><M><K><D><L><Y><A><P><T><L><K><E><T><P><S><D><V><E><T><V><S><H><E><Y><L><L><R><G><G><F><I><R><K><V><A><A><G><I><Y><T><Y><L><P><L><G><R><R><V><L><L><K><I><E><N><I><V><R><E><E><M><N><R><I><G><A><Q><E><I><L><M><P><I><L><Q><P><A><E><L><W><K><Q><S><G><R><W><D><D><Y><G><P><E><M><M><K><L><K><D><R><H><E><R><D><F><T><L><G... | Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two addit... | A5IJQ9 |
Q1BU34 | T23O_BURCA | Tryptophanase | Burkholderia cepacia complex | <M><Q><P><P><G><G><D><A><P><A><G><C><P><F><S><G><A><R><A><A><Q><P><A><Q><A><P><H><E><A><P><H><V><P><G><E><A><D><A><Q><A><G><W><H><N><A><Q><L><D><F><S><K><S><M><S><Y><G><D><Y><L><S><L><N><S><I><L><D><A><Q><H><P><L><S><P><D><H><N><E><M><L><F><I><I><Q><H><Q><T><S><E><L><W><M><K><L><A><L><F><E><L><R><G><A><L><D><A><V><R><T... | Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.<BOP> | Q1BU34 |
Q3AYX2 | FOLD_SYNS9 | Methenyltetrahydrofolate cyclohydrolase | unclassified Synechococcus | <M><A><L><R><L><D><G><K><A><L><A><K><A><V><E><S><R><L><Q><A><Q><I><E><S><N><L><P><Q><A><G><R><P><P><G><L><A><V><L><R><V><G><D><D><P><A><S><A><V><Y><V><A><N><K><E><K><A><C><A><R><I><G><V><A><S><Y><G><A><H><L><P><S><S><T><P><F><A><E><V><L><S><T><I><Q><Q><L><N><A><D><P><R><V><D><G><I><L><L><Q><L><P><L><P><E><G><L><D><E><G... | Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP> | Q3AYX2 |
C4L9W9 | HSLU_TOLAT | Unfoldase HslU | Tolumonas | <M><S><E><M><T><P><R><E><I><V><H><E><L><D><R><H><I><I><G><Q><A><E><A><K><R><A><V><A><I><A><L><R><N><R><W><R><R><M><Q><L><S><N><E><L><R><Q><E><V><A><P><K><N><I><L><M><I><G><P><T><G><V><G><K><T><E><I><A><R><R><L><A><K><L><A><N><A><P><F><I><K><V><E><A><T><K><F><T><E><V><G><Y><V><G><K><E><V><D><T><I><I><R><D><L><T><D><M><A... | ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before... | C4L9W9 |
Q7SDU4 | NACB_NEUCR | Nascent polypeptide complex protein 2 | Neurospora | <M><S><D><V><Q><E><R><L><K><K><L><G><A><S><A><R><I><G><I><G><K><G><T><P><R><R><K><V><K><R><A><P><A><R><S><A><G><D><D><K><K><L><Q><A><T><L><K><K><V><N><V><Q><P><I><Q><A><I><E><E><V><N><M><F><K><S><D><G><N><V><I><H><F><A><A><P><K><V><H><A><A><V><P><A><N><T><F><A><I><Y><G><N><G><E><D><K><E><L><T><E><L><V><P><G><I><L><N><Q... | Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing ... | Q7SDU4 |
C1DAJ6 | YCGR_LARHH | Cyclic di-GMP binding protein YcgR | Laribacter | <M><N><E><T><F><S><V><T><D><L><S><S><D><Q><D><P><A><V><P><H><G><S><H><S><A><P><L><P><S><S><E><D><L><A><K><Y><A><M><T><S><P><L><E><I><G><Q><H><L><K><R><I><I><S><A><N><V><L><V><T><V><F><S><N><H><G><K><S><F><I><L><T><K><L><L><A><I><D><L><K><S><G><R><F><A><F><D><A><G><S><S><D><D><A><N><R><Q><L><L><K><S><E><R><N><V><F><V><C... | Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.<BOP> | C1DAJ6 |
F4KG58 | E70A3_ARATH | Exocyst subunit Exo70 family protein A3 | Arabidopsis | <M><S><N><V><L><D><K><T><N><L><H><E><L><S><I><A><P><K><I><S><T><H><D><E><K><L><Y><E><C><T><K><C><G><I><F><F><H><R><D><S><V><E><S><A><T><E><I><N><P><H><E><N><L><G><E><V><R><A><V><E><D><K><P><N><N><E><S><I><K><V><D><E><R><G><T><C><N><F><H><F><I><D><E><H><H><G><K><V><D><G><I><N><T><E><Y><D><A><S><K><F><K><Q><I><L><E><N><Y... | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion . Involved in PIN4 exocytosis and gravitropic responses in columella cells . By monitoring PIN4 distribution in columella cells, modulates auxin repartition and ... | F4KG58 |
Q81LD3 | SYV_BACAN | Valyl-tRNA synthetase | Bacillus cereus group | <M><S><N><T><E><K><N><L><P><T><K><Y><D><H><M><S><V><E><E><G><L><Y><Q><W><W><L><E><G><K><Y><F><E><A><T><G><D><E><K><K><Q><P><Y><T><I><V><I><P><P><P><N><V><T><G><K><L><H><L><G><H><A><W><D><T><T><L><Q><D><I><L><T><R><T><K><R><M><Q><G><Y><D><V><L><W><L><P><G><M><D><H><A><G><I><A><T><Q><A><K><V><E><G><K><L><R><E><E><G><I><S... | Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.<BOP> | Q81LD3 |
Q9SZU7 | KAI2_ARATH | Protein KARRIKIN INSENSITIVE 2 | Arabidopsis | <M><G><V><V><E><E><A><H><N><V><K><V><I><G><S><G><E><A><T><I><V><L><G><H><G><F><G><T><D><Q><S><V><W><K><H><L><V><P><H><L><V><D><D><Y><R><V><V><L><Y><D><N><M><G><A><G><T><T><N><P><D><Y><F><D><F><D><R><Y><S><N><L><E><G><Y><S><F><D><L><I><A><I><L><E><D><L><K><I><E><S><C><I><F><V><G><H><S><V><S><A><M><I><G><V><L><A><S><L><N... | Involved in seed germination and seedling development. Essential for plant responses to karrikins, a class of butenolide compounds, structurally similar to strigolactones, released from burning vegetation that stimulate seed germination and enhance seedling photomorphogenesis. KAI2 is not required for strigolactone-med... | Q9SZU7 |
Q21BF6 | MODC_RHOPB | Molybdenum import ATP-binding protein ModC | Rhodopseudomonas | <M><R><D><V><S><R><S><I><Q><A><Q><F><R><G><A><L><G><R><F><A><L><D><A><A><F><T><V><P><A><T><G><I><T><G><L><F><G><P><S><G><C><G><K><S><T><V><L><R><C><I><A><G><L><Q><Q><L><P><G><S><T><F><A><I><D><G><D><V><W><Q><D><A><S><Q><F><R><Q><P><H><Q><R><P><I><G><Y><V><F><Q><E><A><S><L><F><A><H><L><S><V><K><A><N><L><L><Y><G><A><P><R... | Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system.<BOP> | Q21BF6 |
P46944 | TRS85_YEAST | Transport protein particle 85 kDa subunit | Saccharomyces | <M><V><F><S><Y><E><H><Y><M><N><L><L><F><H><L><D><N><S><K><E><T><V><P><P><E><I><A><K><R><I><I><S><N><A><I><A><P><V><I><T><V><T><S><T><P><L><F><D><K><H><I><Q><E><T><Y><K><V><D><S><L><Y><M><L><L><R><F><F><G><G><C><V><S><D><R><D><Q><A><N><E><A><K><V><G><Q><H><E><H><E><V><C><D><A><S><D><S><T><D><S><I><P><K><N><K><N><L><E><V... | Specific subunit of the TRAPP III complex that acts as an autophagy-specific guanine nucleotide exchange factor (GEF) for YPT1. TRS85 directs the TRAPP III complex to the phagophore assembly site (PAS) that is involved in autophagosome formation. Required for membrane expansion during autophagy and the CVT pathway. Req... | P46944 |
A0A023IWK7 | AAMAT_AMAPL | Gamma-amanitin | Amanita | <M><S><D><I><N><A><T><R><L><P><I><W><G><I><G><C><N><P><C><V><G><D><E><V><T><A><L><I><T><R><G><E><A> | Major toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters .<BOP> | A0A023IWK7 |
B2IWI8 | EX7S_NOSP7 | Exodeoxyribonuclease VII small subunit | Nostoc | <M><V><K><R><K><G><A><S><S><S><E><E><G><W><N><Y><E><A><K><V><A><E><I><E><G><I><I><T><R><I><E><A><G><E><L><E><L><E><A><V><F><E><Q><F><A><S><A><V><E><Y><L><R><Q><C><E><S><F><L><Q><Q><R><Q><Q><Q><V><D><L><L><I><E><T><L><S><E><E> | Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.<BOP> | B2IWI8 |
Q7MWR7 | PYRG_PORGI | UTP--ammonia ligase | Porphyromonas | <M><A><D><T><K><Y><I><F><V><T><G><G><V><V><S><S><L><G><K><G><I><V><A><A><S><L><G><K><L><L><Q><A><R><G><F><N><V><A><L><Q><K><F><D><P><Y><I><N><I><D><P><G><T><L><N><P><Y><E><H><G><E><C><Y><V><T><E><D><G><H><E><A><D><L><D><L><G><H><Y><E><R><F><L><N><T><P><T><T><R><A><N><N><I><T><T><G><R><I><Y><Q><N><V><I><R><K><E><R><K><G... | Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.<BOP> | Q7MWR7 |
Q4WTT9 | MDR1_ASPFU | ABC multidrug transporter mdr1 | Aspergillus subgen. Fumigati | <M><P><A><P><E><T><G><A><S><S><R><E><K><S><L><E><D><L><Q><V><A><T><L><E><K><G><R><S><T><S><S><F><G><A><D><N><E><K><P><H><D><H><H><S><L><S><D><T><I><M><A><P><P><D><G><K><Q><K><D><H><G><K><A><V><D><L><N><D><D><S><L><F><A><H><L><Q><E><H><E><K><E><V><L><K><R><Q><L><D><A><P><S><V><K><V><S><F><F><T><L><Y><R><Y><A><S><R><K><D... | Pleiotropic ABC efflux transporter that may be involved in A.fumigatus adaptation to azoles such as vorizonazole.<BOP> | Q4WTT9 |
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