accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
Q7V7N4 | MURQ_PROMM | N-acetylmuramic acid 6-phosphate lyase | Prochlorococcus | <M><T><N><V><F><A><D><L><N><L><H><P><S><D><N><R><G><H><L><L><T><E><K><V><N><P><K><S><E><C><L><D><Q><L><T><T><E><S><L><V><T><L><F><C><E><E><D><R><E><P><Q><R><A><V><A><A><A><I><P><E><L><I><Q><A><V><E><A><I><T><D><R><L><R><S><G><G><R><L><F><Y><L><G><A><G><T><S><G><R><L><G><V><L><D><A><A><E><C><P><P><T><F><C><S><D><P><D><L... | Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.<BOP> | Q7V7N4 |
B7GYR8 | ACP_ACIB3 | Acyl carrier protein | Acinetobacter calcoaceticus/baumannii complex | <M><S><D><I><E><Q><R><V><K><Q><A><V><A><E><Q><L><G><L><K><A><E><E><I><K><N><E><A><S><F><M><D><D><L><G><A><D><S><L><D><L><V><E><L><V><M><S><F><E><N><D><F><D><I><T><I><P><D><E><D><S><N><E><I><T><T><V><Q><S><A><I><D><Y><V><T><K><K><L><G> | Carrier of the growing fatty acid chain in fatty acid biosynthesis.<BOP> | B7GYR8 |
Q5J316 | GTR12_BOVIN | Glucose transporter type 12 | Bos | <M><V><P><V><E><N><A><E><G><P><S><L><L><K><P><K><G><R><A><A><E><T><D><G><S><D><R><A><S><G><G><P><H><P><P><W><A><R><G><C><G><M><Y><T><L><L><S><S><V><T><A><A><V><S><G><F><L><V><G><Y><E><L><G><I><I><S><G><A><L><L><Q><I><R><T><L><L><V><L><T><C><H><E><Q><E><M><V><V><S><S><L><L><I><G><A><L><L><A><S><L><I><G><G><V><L><I><D><R... | Insulin-independent facilitative glucose transporter.<BOP> | Q5J316 |
B0SC36 | DAPF_LEPBA | PLP-independent amino acid racemase | Leptospira | <M><K><I><N><F><T><K><M><E><G><I><G><N><D><Y><V><Y><I><D><A><T><K><N><D><I><R><L><S><P><E><Q><I><Q><K><L><S><D><R><N><F><G><I><G><G><D><G><V><I><F><I><R><N><S><N><S><G><E><F><Q><M><D><M><Y><N><S><D><G><S><S><S><E><M><C><G><N><G><V><R><C><V><G><K><F><V><Y><D><H><G><L><T><K><N><Q><K><P><T><I><E><T><G><K><G><V><L><T><L><D... | Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.<BOP> | B0SC36 |
B6J3N7 | SYM_COXB2 | Methionyl-tRNA synthetase | Coxiella | <M><T><T><E><K><R><Q><I><L><V><T><A><A><L><P><Y><A><N><G><P><I><H><L><G><H><M><V><E><H><I><Q><A><D><I><W><V><R><F><Q><R><L><K><G><N><D><C><L><F><I><C><G><E><D><A><H><G><T><A><I><M><I><T><A><Q><K><Q><G><L><P><P><E><A><L><V><A><K><M><H><K><E><H><A><R><D><L><G><G><F><L><I><E><Y><D><N><F><Y><T><T><H><S><P><E><N><R><E><L><A... | Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.<BOP> | B6J3N7 |
A0A1B7YCL6 | DPCHH_COLHI | Diterpenoid pyrone biosynthesis cluster protein H | Colletotrichum destructivum species complex | <M><W><T><G><Q><P><A><S><G><P><P><F><D><H><E><N><H><S><A><S><C><T><Q><H><F><A><L><F><S><S><P><S><P><A><N><S><E><P><K><S><M><L><S><A><W><A><H><R><L><C><V><R><A><V><D><V><L><F><G><T><F><L><Y><V><P><L><G><I><L><F><L><K><K><S><L><S><G><F><G><D><G><D><W><D><S><S><Q><I><P><D><L><H><G><K><V><A><V><V><T><G><G><N><A><G><I><G><Y... | Short chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of the diterpenoid pyrones higginsianins A and B . The first step of the pathway is the synthesis of the alpha-pyrone moiety by the polyketide synthase dpchA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA un... | A0A1B7YCL6 |
B2TY46 | MIAA_SHIB3 | Isopentenyl-diphosphate:tRNA isopentenyltransferase | Shigella | <M><S><D><I><S><K><A><S><L><P><K><A><I><F><L><M><G><P><T><A><S><G><K><T><A><L><A><I><E><L><R><K><I><L><P><V><E><L><I><S><V><D><S><A><L><I><Y><K><G><M><D><I><G><T><A><K><P><N><A><E><E><L><L><A><V><P><H><R><L><L><D><I><R><D><P><S><Q><A><Y><S><A><A><D><F><R><R><D><A><L><A><E><M><A><D><I><T><A><A><G><R><I><P><L><L><V><G><G... | Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).<BOP> | B2TY46 |
O05254 | NUPP_BACSU | Guanosine ABC transporter permease protein NupP | Bacillus | <M><V><K><R><L><S><H><L><L><V><P><L><I><A><I><I><L><G><L><A><A><G><A><L><I><M><L><V><S><G><Y><S><V><A><S><G><Y><S><A><L><W><N><G><I><F><G><E><I><Y><Y><V><G><E><T><I><R><Q><I><T><P><Y><I><L><S><G><L><A><V><A><F><A><F><R><T><G><L><F><N><I><G><V><E><G><Q><L><L><V><G><W><T><A><A><V><W><V><G><T><A><F><D><G><P><A><Y><I><H><L... | Part of an ABC transporter complex involved in the uptake of guanosine . Responsible for the translocation of the substrate across the membrane (Probable). May be a nucleoside transporter of broad specificity but with various affinities for different substrates .<BOP> | O05254 |
Q9JJA9 | GRASP_MOUSE | General receptor for phosphoinositides 1-associated scaffold protein | Mus | <M><T><L><R><R><L><R><K><L><Q><Q><K><E><E><A><T><A><A><P><D><P><A><G><R><A><P><D><S><E><A><A><R><A><A><P><L><P><S><G><P><P><A><A><A><A><P><P><G><A><P><G><E><E><L><Y><A><A><L><E><D><Y><H><P><A><E><L><Y><R><A><L><A><V><S><G><G><T><L><P><R><R><K><G><S><G><F><R><W><K><N><F><T><Q><S><P><E><Q><Q><R><K><V><L><T><L><E><K><G><D... | Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.<BOP> | Q9JJA9 |
Q48V50 | MURI_STRPM | Glutamate racemase | Streptococcus | <M><D><T><R><P><I><G><F><L><D><S><G><V><G><G><L><T><V><V><C><E><L><I><R><Q><L><P><H><E><K><I><V><Y><I><G><D><S><A><R><A><P><Y><G><P><R><P><K><K><Q><I><K><E><Y><T><W><E><L><V><N><F><L><L><T><Q><N><V><K><M><I><V><F><A><C><N><T><A><T><A><V><A><W><E><E><V><K><A><A><L><D><I><P><V><L><G><V><V><L><P><G><A><S><A><A><I><K><S><T... | Provides the (R)-glutamate required for cell wall biosynthesis.<BOP> | Q48V50 |
Q5GS79 | MURG_WOLTR | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase | unclassified Wolbachia | <M><D><I><V><L><A><T><G><G><T><G><G><H><I><F><P><A><I><T><L><A><R><A><I><K><R><Q><G><Y><D><S><I><L><F><A><D><K><K><T><G><K><N><T><D><V><K><D><Y><T><L><P><L><N><K><P><G><G><N><K><F><R><F><F><L><L><L><I><Y><S><C><V><L><A><L><Y><Q><I><R><K><L><K><P><K><L><V><I><G><F><G><G><Y><A><S><F><P><T><L><L><A><A><K><V><L><S><I><P><I... | Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).<BOP> | Q5GS79 |
P42573 | CED3_CAEEL | Cell death protein 3 subunit p13 | Caenorhabditis | <M><M><R><Q><D><R><R><S><L><L><E><R><N><I><M><M><F><S><S><H><L><K><V><D><E><I><L><E><V><L><I><A><K><Q><V><L><N><S><D><N><G><D><M><I><N><S><C><G><T><V><R><E><K><R><R><E><I><V><K><A><V><Q><R><R><G><D><V><A><F><D><A><F><Y><D><A><L><R><S><T><G><H><E><G><L><A><E><V><L><E><P><L><A><R><S><V><D><S><N><A><V><E><F><E><C><P><M><S... | Acts as a cysteine protease in controlling programmed cell death (apoptosis) by proteolytically activating or inactivating a wide range of substrates . Component of the egl-1, ced-9, ced-4 and ced-3 apoptotic signaling cascade required for the initiation of programmed cell death in cells fated to die during embryonic a... | P42573 |
Q31IM5 | UBIE_HYDCU | Demethylmenaquinone methyltransferase | Hydrogenovibrio | <M><T><T><E><H><S><Q><S><K><K><T><I><D><F><G><F><S><E><V><P><L><E><E><K><V><K><K><V><K><G><V><F><D><S><V><A><G><N><Y><D><I><M><N><D><V><M><S><F><G><I><H><R><L><W><K><R><H><A><I><E><L><S><G><I><R><P><G><N><V><V><L><D><L><A><G><G><T><G><D><L><T><K><A><F><A><K><R><V><G><K><T><G><R><V><V><L><A><D><I><N><E><S><M><V><R><V><G... | Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).<BOP> | Q31IM5 |
A9C011 | AMIE_DELAS | Acylamide amidohydrolase | Delftia | <M><R><H><G><D><I><S><S><S><N><D><C><V><G><V><A><V><V><N><Y><K><M><P><R><L><H><T><K><A><E><V><L><D><N><C><R><K><I><A><D><M><L><V><G><M><K><R><G><L><P><G><M><D><L><V><I><F><P><E><Y><S><T><H><G><I><M><Y><D><A><K><E><M><Y><D><T><A><S><A><I><P><G><E><E><T><E><I><F><A><D><A><C><R><R><A><N><V><W><G><V><F><S><L><T><G><E><R><H... | Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.<BOP> | A9C011 |
A6UWZ3 | PDXT_META3 | Pyridoxal 5'-phosphate synthase glutaminase subunit | Methanococcus | <M><N><I><G><I><L><G><I><Q><G><D><I><E><E><H><E><E><M><I><K><K><I><N><H><A><P><K><R><I><R><T><I><E><D><L><K><N><I><D><A><L><I><I><P><G><G><E><S><S><T><M><G><K><L><M><K><T><Y><G><F><I><E><A><L><K><N><A><D><L><P><I><L><G><T><C><A><G><M><V><L><L><S><K><G><T><G><K><E><Q><P><L><L><E><L><M><D><I><T><I><N><R><N><A><Y><G><S><Q... | Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.<BOP> | A6UWZ3 |
B7VLL4 | ARGE_VIBA3 | N-acetylornithinase | Vibrio | <M><Q><L><P><S><F><L><E><V><Y><K><G><L><I><S><T><D><S><I><S><S><T><D><P><S><W><D><H><G><N><E><K><V><I><E><K><M><A><Q><W><F><K><D><V><G><F><S><V><E><V><V><E><V><E><P><G><K><H><N><M><V><A><K><M><G><S><G><E><G><G><L><L><L><A><G><H><S><D><T><V><P><F><D><E><G><R><W><N><F><D><P><H><A><L><T><E><H><N><N><R><F><Y><G><L><G><T><A... | Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids. Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.<BOP> | B7VLL4 |
Q5FB34 | ANRCS_VITVI | Anthocyanidin reductase ((2S)-flavan-3-ol-forming) | Vitis | <M><A><T><Q><H><P><I><G><K><K><T><A><C><V><V><G><G><T><G><F><V><A><S><L><L><V><K><L><L><L><Q><K><G><Y><A><V><N><T><T><V><R><D><P><D><N><Q><K><K><V><S><H><L><L><E><L><Q><E><L><G><D><L><K><I><F><R><A><D><L><T><D><E><L><S><F><E><A><P><I><A><G><C><D><F><V><F><H><V><A><T><P><V><H><F><A><S><E><D><P><E><N><D><M><I><K><P><A><I... | Produces the terminal flavan-3-ol monomers required for the formation of proanthocyanidins or condensed tannins in leaves and flowers, as well as in the skin and seeds of developing berries (Ref.1, PubMed:16169968). Behaves as a reductase and as a C-3 epimerase . Catalyzes the double reduction of anthocyanidins, produc... | Q5FB34 |
A8XNX8 | LGC4_CAEBR | Ligand-gated ion channel 4 | Caenorhabditis | <M><V><I><C><H><S><C><T><T><F><C><I><L><L><V><I><D><L><V><P><C><R><I><V><G><M><E><N><V><E><N><R><V><M><F><S><L><L><D><R><S><P><Q><T><N><D><T><G><P><K><P><E><K><F><E><I><A><K><G><K><F><K><V><L><E><E><N><S><I><G><A><D><T><V><S><H><L><P><T><T><R><E><E><H><V><S><A><V><V><P><M><P><N><F><D><P><H><R><L><E><K><A><L><R><T><K><G... | Acetylcholine receptor.<BOP> | A8XNX8 |
P46943 | GUF1_YEAST | Ribosomal back-translocase | Saccharomyces | <M><L><K><F><R><I><R><P><V><R><H><I><R><C><Y><K><R><H><A><Y><F><L><R><Y><N><H><T><T><T><P><A><Q><K><L><Q><A><Q><I><E><Q><I><P><L><E><N><Y><R><N><F><S><I><V><A><H><V><D><H><G><K><S><T><L><S><D><R><L><L><E><I><T><H><V><I><D><P><N><A><R><N><K><Q><V><L><D><K><L><E><V><E><R><E><R><G><I><T><I><K><A><Q><T><C><S><M><F><Y><K><D... | Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.<BOP> | P46943 |
Q1C1G0 | MTGA_YERPA | Peptidoglycan glycosyltransferase MtgA | Yersinia | <M><I><S><V><R><R><G><F><S><Q><L><W><Y><W><G><K><R><G><V><I><G><I><I><A><L><W><M><A><G><I><L><I><F><A><F><L><P><V><P><F><S><M><V><M><I><E><R><Q><L><G><A><W><L><T><G><D><F><A><Y><V><A><H><S><D><W><V><P><M><D><E><I><S><P><Y><M><A><L><A><V><M><A><A><E><D><Q><K><F><P><D><H><W><G><F><D><V><G><A><I><E><S><A><L><S><H><N><Q><R... | Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.<BOP> | Q1C1G0 |
C0QWX2 | RL11_BRAHW | 50S ribosomal protein L11 | Brachyspira | <M><A><K><K><V><V><G><I><V><K><V><R><I><P><G><G><E><A><T><P><A><P><P><L><G><P><A><L><G><Q><K><Q><I><Q><I><A><A><F><V><K><D><F><N><A><K><T><S><K><M><K><G><Q><L><L><N><T><Y><I><T><V><Y><E><D><K><T><Y><T><F><V><T><K><G><T><S><T><S><T><L><I><K><K><K><L><G><I><E><K><G><S><G><E><P><N><K><T><K><V><A><T><I><N><Q><K><Q><L><E><E... | Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP> | C0QWX2 |
Q1XDQ6 | IF3C_NEOYE | Translation initiation factor IF-3, chloroplastic | Neopyropia | <M><L><E><K><Y><K><N><S><K><K><L><S><R><D><L><P><Q><I><N><D><R><I><R><F><P><K><V><R><V><I><D><D><E><G><E><Q><L><G><I><F><V><P><E><E><A><I><Q><L><A><V><Q><Q><G><L><D><L><V><V><V><S><D><K><S><D><P><P><V><C><R><I><L><D><Y><G><K><Y><K><F><T><Q><E><K><R><A><R><E><A><K><K><K><Q><H><N><S><S><I><K><E><V><K><M><R><Y><K><I><E><E... | IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.<BOP> | Q1XDQ6 |
B4U1C3 | SYS_STREM | Seryl-tRNA(Ser/Sec) synthetase | Streptococcus | <M><L><D><L><K><R><I><R><T><D><F><D><A><V><A><A><K><L><K><T><R><G><V><S><E><D><T><L><T><T><L><K><A><L><D><E><Q><R><R><A><L><L><V><Q><T><E><E><L><K><A><Q><R><N><I><A><S><A><A><I><A><Q><A><K><R><Q><K><K><D><A><S><Q><Q><I><A><D><M><Q><Q><L><A><A><N><I><K><V><I><D><A><K><L><A><D><I><D><Q><E><I><T><S><I><I><T><V><L><P><N><T... | Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).<BOP> | B4U1C3 |
A7ZFB9 | SYE2_CAMC1 | Glutamyl-tRNA synthetase 2 | Campylobacter | <M><I><V><T><R><F><A><P><S><P><T><G><Y><L><H><I><G><G><L><R><T><A><L><Y><N><Y><L><Y><A><R><A><N><N><G><K><F><L><L><R><I><E><D><T><D><L><K><R><N><S><E><E><A><T><Q><A><I><K><E><A><F><A><W><C><K><L><D><H><D><G><E><V><T><Y><Q><S><K><R><F><D><L><Y><K><E><Y><V><K><K><L><L><D><E><G><K><A><Y><K><C><Y><M><S><K><E><E><L><E><E><L... | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP> | A7ZFB9 |
Q47FN7 | GLO2_DECAR | Glyoxalase II | Dechloromonas | <M><L><E><I><S><F><I><P><A><F><K><D><N><Y><I><W><L><L><T><R><G><K><R><A><F><V><V><D><P><G><D><A><A><P><V><L><A><R><L><E><A><G><G><L><M><L><E><G><I><L><I><T><H><H><H><A><D><H><Q><G><G><V><A><E><L><K><A><R><W><Q><A><E><V><Y><A><P><G><N><E><S><I><T><G><C><S><C><P><L><S><G><G><E><S><I><D><V><L><G><Q><K><V><T><V><M><A><V><P... | Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.<BOP> | Q47FN7 |
Q54CC5 | EIF3E_DICDI | Eukaryotic translation initiation factor 3 subunit 6 | Dictyostelium | <M><E><Y><D><L><T><K><Q><I><C><S><F><L><D><A><H><M><M><L><P><L><I><N><Y><L><K><D><T><Q><Q><Y><Q><E><N><E><I><N><K><A><M><A><D><I><L><S><Q><T><G><C><C><D><Y><A><I><N><A><Y><E><S><I><G><R><D><T><A><P><L><Q><A><K><K><Q><E><L><V><G><E><L><N><K><L><K><E><Q><C><S><F><V><T><Q><Y><I><E><S><K><K><Q><Q><K><E><Q><Q><K><E><L><K><E... | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates t... | Q54CC5 |
P75304 | SYV_MYCPN | Valyl-tRNA synthetase | Mycoplasma | <M><D><K><Q><F><S><F><Q><G><Q><Y><D><F><K><T><V><S><T><G><L><Y><D><S><W><S><S><A><S><F><F><K><P><Q><K><N><K><V><P><F><T><A><I><L><P><P><P><N><L><T><G><T><L><H><I><G><H><A><F><E><V><S><I><T><D><Q><I><M><R><F><K><R><L><R><G><Y><G><V><N><W><I><P><G><F><D><H><A><G><I><A><T><Q><T><K><Y><E><K><L><A><R><E><T><N><P><E><Y><F><Q... | Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.<BOP> | P75304 |
C6C187 | RL23_MARSD | 50S ribosomal protein L23 | Maridesulfovibrio | <M><D><Y><T><Q><I><L><I><K><P><V><I><S><E><K><A><T><D><I><K><E><A><A><N><Q><V><A><F><Y><V><L><P><S><A><N><K><T><E><V><K><K><A><V><E><S><A><F><D><V><K><V><D><S><V><R><I><V><R><K><R><P><G><L><R><R><K><F><G><R><V><V><G><K><L><S><G><Y><K><K><A><Y><V><K><L><S><E><G><E><K><I><E><F><F><E><G><V> | One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.<BOP> | C6C187 |
A6V7I3 | FABA_PSEA7 | Trans-2-decenoyl-[acyl-carrier-protein] isomerase | Pseudomonas | <M><T><K><Q><H><A><F><T><R><E><D><L><L><R><C><S><R><G><E><L><F><G><P><G><N><A><Q><L><P><A><P><N><M><L><M><I><D><R><I><V><H><I><S><D><V><G><G><K><Y><G><K><G><E><L><V><A><E><L><D><I><N><P><D><L><W><F><F><A><C><H><F><E><G><D><P><V><M><P><G><C><L><G><L><D><A><M><W><Q><L><V><G><F><Y><L><G><W><Q><G><N><P><G><R><G><R><A><L><G... | Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active ... | A6V7I3 |
P28509 | HIR3_HIRME | Hirudin III | Hirudo | <V><V><Y><T><D><C><T><E><S><G><Q><N><L><C><L><C><E><D><S><N><V><C><G><Q><G><N><K><C><I><L><G><S><N><G><E><K><N><Q><C><V><T><G><E><G><T><P><K><P><Q><S><H><N><D><G><D><F><E><E><I><P><E><E><Y><L><Q> | Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.<BOP> | P28509 |
Q96M20 | CNBD2_HUMAN | Cyclic nucleotide-binding domain-containing protein 2 | Homo | <M><R><R><H><M><V><T><Y><A><W><Q><L><L><K><K><E><L><G><L><Y><Q><L><A><M><D><I><I><I><M><I><R><V><C><K><M><F><R><Q><G><L><R><G><F><R><E><Y><Q><I><I><E><T><A><H><W><K><H><P><I><F><S><F><W><D><K><K><M><Q><S><R><V><T><F><D><T><M><D><F><I><A><E><E><G><H><F><P><P><K><A><I><Q><I><M><Q><K><K><P><S><W><R><T><E><D><E><I><Q><A><V... | Essential for male fertility. Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar bending of sperm.<BOP> | Q96M20 |
Q4UV65 | MSBA_XANC8 | Lipid A export ATP-binding/permease protein MsbA | Xanthomonas | <M><K><T><I><N><E><N><A><P><Q><V><S><S><W><Q><T><Y><R><R><L><L><A><F><A><K><P><Y><R><L><L><L><V><A><A><L><I><A><A><L><I><E><A><A><G><T><T><G><F><L><A><L><M><K><P><I><T><D><E><T><F><I><Y><K><N><A><E><V><S><R><W><L><P><V><Q><I><I><L><L><F><V><I><R><G><A><A><G><Y><I><T><D><M><A><M><G><K><S><A><R><S><I><A><R><D><L><R><V><K... | Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.<BOP> | Q4UV65 |
P35244 | RFA3_HUMAN | Replication factor A protein 3 | Homo | <M><V><D><M><M><D><L><P><R><S><R><I><N><A><G><M><L><A><Q><F><I><D><K><P><V><C><F><V><G><R><L><E><K><I><H><P><T><G><K><M><F><I><L><S><D><G><E><G><K><N><G><T><I><E><L><M><E><P><L><D><E><E><I><S><G><I><V><E><V><V><G><R><V><T><A><K><A><T><I><L><C><T><S><Y><V><Q><F><K><E><D><S><H><P><F><D><L><G><L><Y><N><E><A><V><K><I><I><H... | As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, ... | P35244 |
Q2ST89 | RS18_MYCCT | 30S ribosomal protein S18 | Mycoplasma | <M><Q><V><K><K><I><K><K><R><K><K><V><N><F><F><Q><K><N><N><I><K><Y><I><D><Y><K><D><V><E><L><L><K><K><F><I><S><P><N><G><Q><I><L><P><R><R><I><T><G><T><S><L><K><D><Q><R><Q><L><A><L><A><I><K><R><A><R><Q><M><A><L><L><P><Y><V><I><E> | Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.<BOP> | Q2ST89 |
B0TR04 | LUXS_SHEHH | Autoinducer-2 production protein LuxS | Shewanella | <M><P><L><L><D><S><F><T><V><D><H><T><R><M><N><A><P><A><V><R><I><A><K><S><M><V><T><P><K><G><D><T><I><T><V><F><D><L><R><F><C><V><P><N><K><E><I><L><S><E><R><G><I><H><T><L><E><H><L><F><A><G><F><M><R><E><H><L><N><G><D><S><V><E><I><I><D><I><S><P><M><G><C><R><T><G><F><Y><M><S><L><I><G><A><P><T><E><S><I><V><A><D><S><W><L><A><A... | Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhom... | B0TR04 |
B3QN94 | ARGB_CHLP8 | NAG kinase | Chlorobaculum | <M><E><K><M><C><S><E><F><R><P><D><G><K><R><P><Q><P><V><I><G><H><V><L><V><E><A><L><P><Y><I><R><Q><F><E><G><K><T><F><V><I><K><Y><G><G><A><A><M><K><D><E><V><L><K><N><I><F><A><E><N><V><T><L><L><R><K><V><G><I><K><V><V><I><V><H><G><G><G><D><A><I><T><K><T><S><D><K><M><G><L><E><T><T><F><V><H><G><K><R><V><T><D><L><E><T><I><N><V... | Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.<BOP> | B3QN94 |
Q0A551 | FETP_ALKEH | Probable Fe(2+)-trafficking protein | Alkalilimnicola | <M><T><R><M><V><Q><C><V><R><L><G><R><E><A><E><G><L><P><R><P><P><Y><P><G><E><L><G><K><R><I><Y><E><N><V><S><K><E><A><W><Q><E><W><L><R><H><Q><T><M><L><I><N><E><Y><R><L><T><P><V><E><P><R><A><R><Q><F><L><E><K><E><M><E><N><F><F><F><G><D><G><S><S><A><P><P><D><Y><Q><P><E> | Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.<BOP> | Q0A551 |
Q4UVG6 | CCME2_XANC8 | Heme chaperone CcmE 2 | Xanthomonas | <M><N><P><Q><R><R><R><R><L><W><L><V><L><A><L><V><L><A><G><G><L><A><T><T><L><V><A><M><A><L><Q><R><N><V><A><Y><L><Y><T><P><A><E><V><L><R><G><E><A><G><E><H><A><R><F><R><L><G><G><M><V><E><K><G><S><F><R><R><E><A><G><S><L><E><A><H><F><R><V><T><D><G><D><A><Q><L><P><V><R><Y><D><R><I><L><P><D><L><F><R><E><G><Q><A><V><V><A><T><G... | Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.<BOP> | Q4UVG6 |
Q2GEF1 | SUCC_NEOSM | Succinyl-CoA synthetase subunit beta | Neorickettsia | <M><N><I><H><E><Y><Q><A><K><E><I><L><R><V><C><G><V><P><T><P><A><G><F><L><V><Q><E><D><T><E><T><S><E><I><A><K><S><L><A><R><L><G><G><K><V><F><A><V><K><A><Q><I><H><A><G><G><R><G><K><A><G><G><V><V><I><C><R><S><V><E><E><A><I><D><N><T><K><K><M><L><G><M><N><L><V><T><H><Q><T><S><P><A><G><Q><K><V><R><K><V><Y><I><E><A><G><Q><S><I... | Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinat... | Q2GEF1 |
Q9U297 | KDM4_CAEEL | [histone H3]-trimethyl-L-lysine(9) demethylase 4 | Caenorhabditis | <M><A><S><A><A><T><T><T><H><F><P><S><S><R><I><P><S><E><P><C><A><S><S><G><P><L><F><P><D><D><V><L><F><T><T><E><A><S><S><A><S><S><S><S><C><H><V><E><N><D><S><R><P><L><S><P><T><M><F><T><D><G><R><T><P><V><N><I><S><A><K><H><L><K><D><H><P><L><H><E><P><T><G><T><S><E><V><L><T><F><Y><P><T><M><R><E><F><K><N><F><S><Q><Y><I><K><K><I... | Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code . Demethylation of Lys residue generates formaldehyde and succinate. Involved in the negative regulation of lifespan in a germline-dependent fashion .<BOP> | Q9U297 |
B1LB31 | NADA_THESQ | Quinolinate synthase | unclassified Thermotoga | <M><V><D><E><I><L><K><L><K><K><E><K><G><Y><I><I><L><A><H><N><Y><Q><I><P><E><L><Q><D><I><A><D><F><V><G><D><S><L><Q><L><A><R><K><A><M><E><L><S><E><K><K><I><L><F><L><G><V><D><F><M><A><E><L><V><K><I><L><N><P><D><K><K><V><I><V><P><D><R><S><A><T><C><P><M><A><N><H><L><T><P><E><I><I><R><E><Y><R><E><K><F><P><D><V><P><V><V><L><Y... | Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.<BOP> | B1LB31 |
Q9ZMN5 | METK_HELPJ | Methionine adenosyltransferase | Helicobacter | <M><K><D><S><F><L><F><T><S><E><S><V><T><E><G><H><P><D><K><M><A><D><Q><I><S><D><A><V><L><D><Y><I><I><E><R><D><K><K><A><K><V><A><C><E><T><L><V><S><N><G><F><C><M><I><T><G><E><L><K><T><S><V><Y><A><P><M><Q><E><I><A><R><E><V><V><K><K><I><G><Y><T><D><A><L><Y><G><F><D><Y><R><S><A><A><V><L><N><G><I><G><E><Q><S><P><D><I><N><Q><G... | Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.<BOP> | Q9ZMN5 |
Q8RI80 | VATD_FUSNN | V-ATPase subunit D | Fusobacterium | <M><A><K><L><K><V><N><P><T><R><M><A><L><S><E><L><K><K><R><L><V><T><A><R><R><G><H><K><L><L><K><D><K><Q><D><E><L><M><R><Q><F><I><N><L><I><K><E><N><K><K><L><R><V><E><V><E><K><E><L><S><D><S><F><K><S><F><L><L><A><S><A><T><M><S><P><L><F><L><E><S><A><I><S><F><P><K><E><K><I><A><V><E><M><K><L><K><N><I><M><S><V><N><V><P><E><M><K... | Produces ATP from ADP in the presence of a proton gradient across the membrane.<BOP> | Q8RI80 |
Q5AUX9 | DBAG_EMENI | Derivative of benzaldehyde biosynthesis cluster protein G | Aspergillus subgen. Nidulantes | <M><P><E><D><G><P><P><K><D><I><P><D><G><L><I><E><E><L><A><L><R><A><F><F><H><D><Y><C><V><V><P><V><N><T><A><L><S><R><G><Y><L><G><G><L><E><P><M><V><H><R><L><G><L><Q><S><P><V><A><N><A><C><K><A><V><A><F><A><S><H><G><L><K><L><S><R><P><F><L><T><K><K><G><E><I><L><Y><H><E><L><L><G><S><L><A><R><S><I><Q><N><P><A><L><G><A><G><P><D... | Transcription factor that coregulates the expression of the gene cluster that mediates the biosynthesis of the antibiotic 2,4- dihydroxy-3-methyl-6-(2-oxopropyl)benzaldehyde (DHMBA) and its derivatives . Specifically positively regulates the expression of the FAD-dependent oxidoreductase dbaF .<BOP> | Q5AUX9 |
Q8VZQ0 | NRX3_ARATH | Probable nucleoredoxin 3 | Arabidopsis | <M><A><V><S><A><D><Y><Q><V><K><F><P><E><S><G><D><L><Y><S><I><L><A><A><E><G><I><E><F><L><L><S><H><S><G><E><V><P><L><E><Y><I><H><G><K><T><I><C><L><F><F><S><A><I><W><C><R><P><C><K><D><F><T><P><E><L><I><K><L><Y><E><N><L><Q><N><R><G><E><E><L><E><I><I><F><V><S><F><D><H><D><M><T><S><F><Y><E><H><F><W><C><M><P><W><L><A><V><P><F... | Probable thiol-disulfide oxidoreductase that may participate in various redox reactions.<BOP> | Q8VZQ0 |
Q9P0P8 | MRES1_HUMAN | Mitochondrial transcription rescue factor 1 | Homo | <M><A><M><A><S><V><K><L><L><A><G><V><L><R><K><P><D><A><W><I><G><L><W><G><V><L><R><G><T><P><S><S><Y><K><L><C><T><S><W><N><R><Y><L><Y><F><S><S><T><K><L><R><A><P><N><Y><K><T><L><F><Y><N><I><F><S><L><R><L><P><G><L><L><L><S><P><E><C><I><F><P><F><S><V><R><L><K><S><N><I><R><S><T><K><S><T><K><K><S><L><Q><K><V><D><E><E><D><S><D... | Mitochondrial RNA-binding protein involved in mitochondrial transcription regulation. Functions as a protective factor to maintain proper mitochondrial RNA level during stress. Acts at the transcription level and its protective function depends on its RNA binding ability . Part of a mitoribosome-associated quality cont... | Q9P0P8 |
Q9JIB4 | TF2H2_MOUSE | TFIIH basal transcription factor complex p44 subunit | Mus | <M><D><E><E><P><E><R><T><K><R><W><E><G><G><Y><E><R><T><W><E><I><L><K><E><D><E><T><G><S><L><K><A><T><I><E><D><I><L><F><K><A><K><R><K><R><V><F><E><H><H><G><Q><V><R><L><G><M><M><R><H><L><Y><V><V><V><D><G><S><R><T><M><E><D><Q><D><L><K><P><N><R><L><T><C><T><L><K><L><L><E><Y><F><V><E><E><Y><F><D><Q><N><P><I><S><Q><I><G><I><I... | Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allo... | Q9JIB4 |
Q5PC26 | PYRE_SALPA | Orotate phosphoribosyltransferase | Salmonella | <M><K><P><Y><Q><R><Q><F><I><E><F><A><L><N><K><Q><V><L><K><F><G><E><F><T><L><K><S><G><R><K><S><P><Y><F><F><N><A><G><L><F><N><T><G><R><D><L><A><L><L><G><R><F><Y><A><E><A><L><V><D><S><G><I><E><F><D><L><L><F><G><P><A><Y><K><G><I><P><I><A><T><T><T><A><V><A><L><A><E><H><H><D><K><D><L><P><Y><C><F><N><R><K><E><A><K><D><H><G><E... | Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).<BOP> | Q5PC26 |
Q9R342 | EFTU_DEIRA | Elongation factor Tu | Deinococcus | <M><A><K><G><T><F><E><R><T><K><P><H><V><N><I><G><T><I><G><H><V><D><H><G><K><T><T><L><T><A><A><I><T><F><T><A><A><S><A><D><P><T><I><E><T><L><A><Y><D><Q><I><D><K><A><P><E><E><K><A><R><G><I><T><I><N><T><A><H><V><E><Y><Q><T><E><T><R><H><Y><S><H><V><D><C><P><G><H><A><D><Y><V><K><N><M><I><T><G><A><A><Q><M><D><G><A><I><L><V><V... | This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.<BOP> | Q9R342 |
O22759 | IDD12_ARATH | Protein indeterminate-domain 12 | Arabidopsis | <M><F><S><S><H><S><L><S><Y><K><L><S><S><L><S><T><E><A><S><A><S><S><G><N><N><T><L><S><T><I><Q><E><F><S><G><F><H><N><V><I><S><S><V><C><T><H><T><E><T><H><K><P><K><K><K><R><G><L><P><G><N><P><D><P><D><A><E><V><I><A><L><S><P><K><T><L><L><A><T><N><R><F><V><C><E><I><C><N><K><G><F><Q><R><D><Q><N><L><Q><L><H><R><R><G><H><N><L><P... | Probable transcription factor.<BOP> | O22759 |
Q3K8E9 | RLMD_PSEPF | 23S rRNA(m5U1939)-methyltransferase | Pseudomonas | <M><A><K><H><E><R><G><L><R><F><Q><P><T><G><G><S><K><A><P><Q><I><P><T><G><K><K><Q><R><L><S><I><E><R><L><A><N><D><G><R><G><I><A><F><F><E><G><K><T><W><F><V><L><G><A><L><A><G><E><E><V><E><A><R><V><L><G><A><H><G><K><V><V><E><A><R><T><E><R><V><F><S><A><S><E><L><R><R><P><A><P><C><Q><H><A><G><R><C><G><G><C><S><V><Q><H><L><P><H... | Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.<BOP> | Q3K8E9 |
B0T7B6 | FABA_CAUSK | Trans-2-decenoyl-[acyl-carrier-protein] isomerase | unclassified Caulobacter | <M><Q><Q><S><S><Y><T><F><D><E><L><L><A><C><G><R><G><E><M><F><G><P><G><N><A><Q><L><P><A><P><P><M><L><M><F><D><R><I><V><R><I><E><S><D><G><G><K><Y><G><K><G><Y><V><E><A><E><F><D><I><N><P><D><L><W><F><F><A><C><H><F><I><G><D><P><V><M><P><G><C><L><G><L><D><A><M><W><Q><L><V><G><F><F><L><G><W><S><G><G><P><G><R><G><R><A><L><G><V... | Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active ... | B0T7B6 |
P02874 | LEC_ONOVI | null | Onobrychis | <A><E><N><T><V><S><F><D><F><S><K><F><L><S><G><Q><E><N><L><I><L><Q><G><D><T><V><T><D><D><S><N><R><C><L><V><L><T><R><E><N><N><G><R><P><V><Q><D><S><V><G><R><V><L><Y><Q><T><P><I><H><L><W><D><K><Q><I><D><K><E><A><S><F><E><T><S><F><T><F><F><I><Y><R><E><N><I><N><R><G><G><D><G><I><T><F><F><L><A><P><T><D><T><Q><P><K><S><G><G><G... | D-mannose and D-glucose specific lectin.<BOP> | P02874 |
Q6NCE7 | MTGA_RHOPA | Peptidoglycan glycosyltransferase MtgA | Rhodopseudomonas | <M><S><D><P><V><A><S><A><P><R><T><K><R><V><V><R><I><V><I><L><V><A><L><A><L><L><A><L><P><Y><L><L><T><I><L><Y><G><G><G><Q><P><V><S><T><L><M><L><W><R><W><A><T><G><A><P><V><S><R><T><W><I><D><I><E><N><I><S><P><A><L><P><R><S><V><V><A><A><E><D><A><K><F><C><S><H><H><G><I><D><W><D><S><V><R><D><V><I><D><D><M><Q><D><G><E><A><S><R... | Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.<BOP> | Q6NCE7 |
Q9ZJL8 | CLPX_HELPJ | ATP-dependent Clp protease ATP-binding subunit ClpX | Helicobacter | <M><N><E><T><L><Y><C><S><F><C><K><K><P><E><S><R><D><P><K><K><R><R><I><I><F><A><S><N><L><N><K><D><V><C><V><C><E><Y><C><I><D><V><M><H><G><E><L><H><K><Y><D><S><K><Y><D><R><M><D><S><L><L><A><L><K><R><D><R><L><R><R><M><E><S><S><A><Y><E><E><E><F><L><L><S><R><I><P><A><P><K><E><L><K><A><V><L><D><N><Y><V><I><G><Q><E><Q><A><K><K... | ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.<BOP> | Q9ZJL8 |
Q47WN0 | MUTS_COLP3 | DNA mismatch repair protein MutS | Colwellia | <M><T><T><A><T><K><D><L><S><S><H><T><P><M><M><R><Q><Y><L><T><I><K><A><E><F><P><H><T><L><I><F><Y><R><M><G><D><F><Y><E><L><F><F><D><D><A><K><K><A><S><D><L><L><D><I><S><L><T><A><R><G><K><T><G><G><N><A><I><P><M><A><G><V><P><Y><H><A><A><E><N><Y><L><A><K><L><V><A><L><G><E><S><V><A><I><C><E><Q><I><G><D><P><A><T><S><K><G><P><V... | This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.<BOP> | Q47WN0 |
Q8U1M0 | NSR_PYRFU | NAD(P)H oxidase | Pyrococcus | <M><E><K><K><K><V><V><I><I><G><G><G><A><A><G><M><S><A><A><S><R><V><K><R><L><R><P><E><W><D><V><K><V><F><E><A><T><E><W><V><S><H><A><P><C><G><I><P><Y><V><V><E><G><I><A><P><K><E><K><L><M><H><Y><P><P><E><V><F><I><K><K><R><G><I><D><L><H><L><K><A><E><V><I><E><V><E><T><G><Y><V><R><V><R><E><N><G><E><E><K><S><Y><E><W><D><Y><L><V... | Catalyzes the CoA-dependent reduction of elemental sulfur (S(0)) to produce hydrogen sulfide . Can use both NADPH and NADH, but shows a preference for NADPH . May enable S(0) to be used, via sulfide, for iron-sulfur cluster synthesis by SipA (Probable). Also shows coenzyme A disulfide reductase (CoADR) activity with bo... | Q8U1M0 |
C5CHA8 | GYRA_KOSOT | DNA gyrase subunit A | Kosmotoga | <M><P><E><E><I><I><S><R><S><I><N><D><E><M><I><T><S><Y><M><L><Y><S><M><S><V><I><V><G><R><A><I><P><D><V><R><D><G><L><K><P><V><Q><R><K><I><L><F><G><M><L><E><L><G><L><R><H><N><Q><S><Y><K><K><S><A><R><I><V><G><E><V><M><G><K><F><H><P><H><G><D><M><A><I><Y><D><A><L><V><R><M><A><Q><P><F><S><M><R><Y><P><L><I><Q><G><Q><G><N><F><G... | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which invo... | C5CHA8 |
C5B9K4 | PAND_EDWI9 | Aspartate 1-decarboxylase alpha chain | Edwardsiella | <M><V><R><T><M><L><Q><G><K><L><H><R><V><K><V><T><Q><S><D><L><N><Y><E><G><S><C><A><I><D><Q><D><F><L><N><A><A><G><I><L><Q><Y><E><A><I><D><I><Y><N><V><D><N><G><Q><R><F><S><T><Y><A><I><A><A><E><P><G><S><K><I><I><S><V><N><G><A><A><A><R><C><A><C><V><G><D><T><L><I><I><C><S><Y><V><Q><I><P><D><E><Q><A><R><T><H><H><P><R><V><V><Y... | Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.<BOP> | C5B9K4 |
M1VDX3 | DTCYB_STRSQ | Pentamethylcyclopentadecatrienol synthase | Streptomyces | <M><D><L><P><P><A><L><L><S><F><Y><C><P><I><A><S><E><V><S><P><E><H><E><A><V><A><Q><E><M><Y><A><W><I><H><A><M><S><L><T><S><D><N><R><Q><A><K><M><L><A><Q><A><G><A><G><F><N><S><Y><F><T><P><R><A><R><G><E><L><A><R><A><L><S><K><Y><N><V><C><A><W><I><A><N><G><M><V><Q><E><I><R><D><P><G><T><F><G><A><M><A><A><R><W><A><R><I><M><E><E... | Diterpene cyclases that can form multiple diterpene products.<BOP> | M1VDX3 |
P45281 | RL25_HAEIN | 50S ribosomal protein L25 | Haemophilus | <M><A><F><K><F><N><A><E><V><R><T><A><Q><G><K><G><A><S><R><R><L><R><H><N><G><Q><I><P><A><I><V><Y><G><G><S><E><E><P><V><S><I><I><L><N><H><D><E><L><N><N><A><Q><A><H><E><S><F><Y><S><E><V><I><T><L><V><V><E><G><K><E><V><A><V><K><V><Q><A><M><Q><R><H><P><F><K><P><K><L><V><H><I><D><F><K><R><A> | This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.<BOP> | P45281 |
B1VUW6 | SAHH_STRGG | S-adenosyl-L-homocysteine hydrolase | Streptomyces | <M><T><T><A><T><N><R><Q><D><F><K><V><A><D><L><S><L><A><P><F><G><R><K><E><I><T><L><A><E><H><E><M><P><G><L><M><S><I><R><K><E><F><A><A><A><Q><P><L><A><G><A><R><I><T><G><S><L><H><M><T><V><Q><T><A><V><L><I><E><T><L><V><A><L><G><A><E><V><R><W><A><S><C><N><I><F><S><T><Q><D><H><A><A><A><A><I><A><V><G><P><N><G><T><P><E><A><P><A... | May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.<BOP> | B1VUW6 |
Q14G22 | MINE_FRAT1 | Cell division topological specificity factor | Francisella | <M><L><A><K><L><F><G><L><S><K><K><Q><Q><S><A><S><V><A><K><E><R><L><Q><I><I><V><A><H><Q><R><S><E><L><H><P><R><S><S><K><I><S><S><H><L><L><A><E><L><K><D><E><I><I><E><V><V><K><K><Y><V><A><L><S><E><E><N><I><R><D><I><D><L><K><V><E><D><S><S><K><N><S><T><I><E><V><N><I><P><F><N> | Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.<BOP> | Q14G22 |
Q4ZVE9 | Y1826_PSEU2 | Nucleoid-associated protein Psyr_1826 | Pseudomonas syringae | <M><M><K><G><G><M><A><G><L><M><K><Q><A><Q><Q><M><Q><E><K><M><A><K><M><Q><E><E><L><A><N><A><E><V><T><G><Q><S><G><A><G><L><V><S><V><V><M><T><G><R><H><D><V><K><R><I><N><L><D><D><S><L><M><Q><E><D><K><E><V><L><E><D><L><I><A><A><A><V><N><D><A><V><R><K><I><E><Q><A><S><Q><D><K><T><A><S><M><T><A><G><M><Q><L><P><P><G><M><K><L><P... | Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP> | Q4ZVE9 |
B8EDV0 | ATPB_SHEB2 | F-ATPase subunit beta | Shewanella | <M><S><T><G><T><V><V><Q><V><I><G><A><V><V><D><V><E><F><P><Q><D><A><V><P><Q><V><Y><D><A><L><K><I><V><G><E><G><P><C><N><G><L><V><L><E><V><Q><Q><Q><L><G><G><G><V><V><R><T><I><A><M><G><S><S><D><G><L><R><R><G><L><E><V><V><N><S><G><S><P><I><T><V><P><V><G><T><A><T><L><G><R><I><M><N><V><L><G><E><P><I><D><E><A><G><P><I><G><E><E... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP> | B8EDV0 |
B2S801 | RLMH_BRUA1 | rRNA (pseudouridine-N3-)-methyltransferase RlmH | Brucella | <M><R><V><S><V><F><A><V><G><R><M><K><S><G><P><E><R><E><L><V><E><R><Y><F><D><R><F><A><K><A><G><P><P><L><G><L><E><F><A><G><V><S><E><I><P><E><S><R><G><Q><T><A><Q><L><R><K><A><E><E><A><Q><R><I><H><E><A><L><D><N><A><K><S><G><G><T><S><S><G><G><A><A><L><I><L><L><D><E><R><G><K><T><L><G><S><E><A><F><A><A><I><V><G><R><M><R><D><D... | Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.<BOP> | B2S801 |
B8D9J5 | ENO_BUCA5 | 2-phosphoglycerate dehydratase | Buchnera | <M><S><K><I><T><K><I><I><A><R><E><I><I><D><S><R><G><N><P><T><V><E><S><E><V><H><L><E><G><G><F><V><G><L><A><S><S><P><S><G><A><S><T><G><S><L><E><A><L><E><L><R><D><E><N><K><D><R><F><M><G><K><G><V><E><K><A><V><S><L><I><N><E><K><I><S><I><A><L><K><N><K><N><A><R><N><Q><S><D><I><D><H><I><M><I><D><L><D><G><T><I><N><K><S><K><L><G... | Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.<BOP> | B8D9J5 |
P52989 | SWRI_SERLI | Autoinducer synthesis protein SwrI | Serratia | <M><I><E><L><F><D><V><D><Y><N><L><L><P><D><N><R><S><K><E><L><F><S><L><R><K><K><T><F><K><D><R><L><D><W><L><V><N><C><E><N><N><M><E><F><D><E><Y><D><N><R><H><A><T><Y><I><F><G><T><Y><Q><N><H><V><I><C><S><L><R><F><I><E><T><K><Y><P><N><M><I><S><D><G><V><F><D><T><Y><F><N><D><I><K><L><P><D><G><N><Y><V><E><A><S><R><L><F><I><D><K... | Required for the synthesis of BHL (N-butanoyl-L-homoserine lactone).<BOP> | P52989 |
Q8Y668 | PYRE_LISMO | Orotate phosphoribosyltransferase | Listeria | <M><S><I><E><K><Q><V><A><E><Q><L><L><E><I><K><A><V><F><L><K><P><N><E><P><F><T><W><A><S><G><I><K><S><P><I><Y><C><D><N><R><L><T><L><G><F><P><K><V><R><Q><F><I><A><K><S><L><A><E><K><I><K><Q><T><F><G><E><I><D><V><V><A><G><T><A><T><A><G><I><P><H><A><A><W><V><S><D><L><L><D><L><P><M><V><Y><V><R><S><K><A><K><E><H><G><K><G><N><Q... | Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).<BOP> | Q8Y668 |
C3KWE8 | ACCD_CLOB6 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | Clostridium | <M><L><K><N><L><F><R><K><T><K><Y><I><T><V><S><Q><K><N><I><E><N><Y><K><R><E><N><T><P><T><I><P><D><G><M><W><V><K><C><N><K><C><G><E><I><L><Y><Q><N><D><L><E><K><N><Y><M><V><C><N><L><C><G><N><H><F><R><I><G><A><K><E><R><I><K><Y><L><F><D><K><D><T><F><K><E><W><D><Y><K><V><K><T><E><N><P><L><N><F><K><G><Y><D><E><K><I><E><N><I><K... | Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.<BOP> | C3KWE8 |
A0P9L2 | IKBP1_ONCMY | Interleukin-1 receptor-associated kinase 1-binding protein 1 homolog | Oncorhynchus | <M><A><I><S><P><S><R><V><F><A><A><L><L><P><T><A><G><D><I><Y><R><D><E><N><E><P><G><M><G><G><H><T><V><T><V><Q><R><T><Q><N><S><A><R><E><V><Q><V><T><G><S><A><E><V><S><C><P><A><D><R><A><T><V><S><V><S><F><K><N><S><K><E><S><V><N><D><V><T><N><S><I><S><R><R><V><E><Y><I><L><Q><T><L><R><Q><H><H><V><K><G><E><E><L><T><V><T><R><H><I... | May be part of a signaling pathway that leads to NF-kappa-B activation.<BOP> | A0P9L2 |
Q92J42 | ODO1_RICCN | Alpha-ketoglutarate dehydrogenase | spotted fever group | <M><G><E><D><F><K><K><T><G><Y><L><F><G><G><N><A><V><F><V><E><E><L><Y><K><Q><Y><L><A><N><P><A><S><V><D><Q><T><W><Q><E><F><F><A><G><I><K><D><N><N><T><L><L><N><K><S><T><A><K><I><I><I><P><D><E><I><K><K><E><S><L><N><N><N><L><S><S><E><D><L><N><S><L><K><A><K><E><M><I><N><A><Y><R><K><H><A><H><Y><L><A><N><L><D><P><L><G><L><E><L... | E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).<BOP> | Q92J42 |
Q895K8 | ISPT_CLOTE | Isoprenyl transferase | Clostridium | <M><W><N><I><F><K><N><K><S><G><Q><S><H><K><V><K><D><K><F><Q><L><D><L><D><N><I><P><K><H><I><A><I><I><M><D><G><N><G><R><W><A><K><E><R><K><L><P><R><S><L><G><H><K><A><G><V><E><T><I><R><D><I><V><K><E><C><N><N><I><G><V><R><Y><L><T><L><Y><A><F><S><T><E><N><W><K><R><P><K><E><E><I><N><A><L><M><E><L><L><V><N><Y><L><R><K><E><V><A... | Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.<BOP> | Q895K8 |
Q69YQ0 | CYTSA_HUMAN | Sperm antigen with calponin homology and coiled-coil domains 1-like | Homo | <M><K><K><A><S><R><S><V><G><S><V><P><K><V><S><A><I><S><K><T><Q><T><A><E><K><I><K><P><E><N><S><S><S><A><S><T><G><G><K><L><V><K><P><G><T><A><A><S><L><S><K><T><K><S><S><D><D><L><L><A><G><M><A><G><G><V><T><V><T><N><G><V><K><G><K><K><S><T><C><P><S><A><A><P><S><A><S><A><P><A><M><T><T><V><E><N><K><S><K><I><S><T><G><T><A><S><S... | Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.<BOP> | Q69YQ0 |
B6V873 | MEP2_TRITO | Fungalysin MEP2 | Trichophyton | <M><H><G><L><L><L><A><G><L><A><A><A><L><P><L><G><V><A><G><L><P><A><R><Q><Q><S><G><L><S><P><R><G><I><D><I><N><P><Y><R><F><A><S><M><A><K><Y><S><E><H><K><A><T><S><Q><M><V><H><S><F><S><Y><S><K><D><D><D><Y><V><A><T><A><T><K><L><V><K><S><T><F><P><N><M><T><F><R><T><V><K><D><H><Y><I><G><T><N><G><I><G><H><V><H><F><K><Q><T><A><H... | Secreted metalloproteinase probably acting as a virulence factor.<BOP> | B6V873 |
A9IFF9 | OBG_BORPD | GTP-binding protein Obg | Bordetella | <M><K><F><V><D><E><A><T><I><E><V><I><A><G><K><G><G><N><G><V><A><S><F><R><R><E><K><F><I><P><K><G><G><P><D><G><G><D><G><G><R><G><G><S><I><Y><A><V><A><D><R><N><I><N><T><L><I><D><F><R><Y><A><R><L><H><R><A><K><N><G><E><N><G><R><G><S><D><Q><Y><G><A><A><A><P><D><I><T><L><R><V><P><V><G><T><V><V><H><D><A><D><T><G><E><L><L><F><D... | An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B... | A9IFF9 |
Q8XB41 | MNME_ECO57 | tRNA modification GTPase MnmE | Escherichia | <M><S><D><N><D><T><I><V><A><Q><A><T><P><P><G><R><G><G><V><G><I><L><R><I><S><G><F><K><A><R><E><V><A><E><T><V><L><G><K><L><P><K><P><R><Y><A><D><Y><L><P><F><K><D><A><D><G><S><V><L><D><Q><G><I><A><L><W><F><P><G><P><N><S><F><T><G><E><D><V><L><E><L><Q><G><H><G><G><P><V><I><L><D><L><L><L><K><R><I><L><T><I><P><G><L><R><I><A><R... | Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP> | Q8XB41 |
Q8MIZ3 | DCPS_PIG | Scavenger mRNA-decapping enzyme DcpS | Sus | <M><A><D><T><A><P><Q><P><S><K><R><K><R><E><R><D><P><E><E><A><E><A><P><S><T><E><E><K><E><A><R><V><G><N><G><T><S><A><P><V><R><L><P><F><S><G><F><R><V><K><K><V><L><R><E><S><A><R><D><K><I><I><F><L><H><G><K><V><N><E><A><S><G><D><G><D><G><E><D><A><I><V><I><L><E><K><T><P><F><Q><V><D><Q><V><A><Q><L><L><M><G><S><P><E><L><Q><L><Q... | Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonu... | Q8MIZ3 |
A1S8R8 | PTH_SHEAM | Peptidyl-tRNA hydrolase | Shewanella | <M><C><D><I><K><L><I><V><G><L><A><N><P><G><A><E><Y><A><Q><T><R><H><N><A><G><A><W><Y><V><E><E><L><A><R><I><A><N><V><S><L><A><P><D><P><K><Y><F><G><L><T><A><R><A><I><L><C><G><K><D><V><R><L><L><I><P><S><T><F><M><N><L><S><G><K><S><V><A><A><L><A><N><F><F><R><I><E><P><E><Q><I><L><V><A><H><D><E><L><D><M><E><P><G><V><A><R><F><K... | The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.<BOP> | A1S8R8 |
Q5WKZ0 | IOLB_ALKCK | 5-deoxy-glucuronate isomerase | Alkalihalobacillus | <M><G><Q><L><L><K><K><P><K><T><K><V><L><K><Q><G><V><T><L><V><H><D><T><E><A><E><K><A><P><L><K><Y><V><S><F><K><L><V><D><I><Q><A><N><A><I><Y><E><E><T><L><G><S><Y><E><C><C><I><V><V><V><R><G><T><V><T><V><T><D><G><E><H><V><F><S><N><I><G><T><R><S><S><V><F><E><R><K><P><T><D><S><V><Y><L><S><N><G><R><S><F><T><V><T><G><T><S><E><A... | Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D-gluconate).<BOP> | Q5WKZ0 |
Q2FHJ4 | RNH2_STAA3 | Ribonuclease HII | Staphylococcus | <M><T><L><T><I><K><E><V><T><Q><L><I><N><A><V><N><T><I><E><E><L><E><N><H><E><C><F><L><D><E><R><K><G><V><Q><N><A><I><A><R><R><R><K><A><L><E><K><E><Q><A><L><K><E><K><Y><V><E><M><T><Y><F><E><N><E><I><L><K><E><H><P><N><A><I><I><C><G><I><D><E><V><G><R><G><P><L><A><G><P><V><V><A><C><A><T><I><L><N><S><N><H><N><Y><L><G><L><D><D... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | Q2FHJ4 |
Q6AWY3 | GRF6_ORYSJ | Transcription activator GRF6 | Oryza sativa | <M><D><L><G><G><G><V><G><V><V><M><A><A><V><D><G><G><G><G><G><E><L><G><G><G><G><L><L><G><S><R><L><M><K><H><G><R><G><N><A><G><D><Q><E><H><E><W><R><P><P><A><K><Q><A><R><G><G><D><A><S><S><A><A><A><A><V><A><A><A><A><A><V><S><E><A><V><K><V><A><A><P><F><L><L><G><A><S><C><S><P><G><H><G><G><E><Q><M><L><S><F><S><S><S><A><S><S><C... | Transcription activator that plays a regulatory role in gibberellin-induced stem elongation.<BOP> | Q6AWY3 |
B1IVX6 | MATP_ECOLC | Macrodomain Ter protein | Escherichia | <M><K><Y><Q><Q><L><E><N><L><E><S><G><W><K><W><K><Y><L><V><K><K><H><R><E><G><E><L><I><T><R><Y><I><E><A><S><A><A><Q><E><A><V><D><V><L><L><S><L><E><N><E><P><V><L><V><N><G><W><I><D><K><H><M><N><P><E><L><V><N><R><M><K><Q><T><I><R><A><R><R><K><R><H><F><N><A><E><H><Q><H><T><R><K><K><S><I><D><L><E><F><I><V><W><Q><R><L><A><G><L... | Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.<BOP> | B1IVX6 |
Q8XD41 | YGFZ_ECO57 | tRNA-modifying protein YgfZ | Escherichia | <M><A><F><T><P><F><P><P><R><Q><P><T><A><S><A><R><L><P><L><T><L><M><T><L><D><D><W><A><L><A><T><I><T><G><A><D><S><E><K><Y><L><Q><G><Q><V><T><A><D><V><S><Q><M><T><D><D><Q><H><L><L><A><A><H><C><D><A><K><G><K><M><W><S><N><L><R><L><F><R><D><G><D><G><F><A><W><I><E><R><R><S><V><R><E><P><Q><L><A><E><L><K><K><Y><A><V><F><S><K><V... | Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.<BOP> | Q8XD41 |
A1SKY7 | GCS21_NOCSJ | Gamma-glutamylcysteine synthetase 2-1 | Nocardioides | <M><V><R><K><L><G><I><E><E><E><L><L><L><F><D><P><E><S><G><E><V><V><P><A><A><P><S><V><L><K><E><F><R><E><H><G><P><G><R><Q><R><A><R><A><A><T><D><E><L><D><Q><E><L><F><R><H><Q><L><E><T><R><T><D><P><V><R><R><A><A><D><A><L><D><Q><L><V><A><A><R><R><T><A><G><E><A><A><R><A><A><G><Y><A><A><G><A><C><G><I><V><P><L><G><G><D><R><S><V... | ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.<BOP> | A1SKY7 |
P57934 | CSRA_PASMU | Carbon storage regulator | Pasteurella | <M><L><I><L><T><R><K><V><G><E><S><L><L><I><G><D><D><I><S><I><T><I><L><N><I><R><G><N><Q><V><K><I><G><I><K><A><P><K><D><V><S><V><H><R><E><E><I><Y><Q><R><I><K><Q><A><L><E><A><P><H><V><G><E> | A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding... | P57934 |
Q1BSL3 | GATB_BURCA | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B | Burkholderia cepacia complex | <M><A><T><Q><W><E><V><V><I><G><L><E><T><H><A><Q><L><S><T><V><S><K><I><F><S><G><A><S><T><Q><F><G><A><E><P><N><T><Q><A><C><P><V><D><L><A><L><P><G><V><L><P><V><L><N><R><G><A><V><E><R><A><I><R><F><G><L><A><I><G><S><T><I><A><P><R><S><I><F><A><R><K><N><Y><F><Y><P><D><L><P><K><G><Y><Q><I><S><Q><Y><E><I><P><V><V><Q><G><G><Q><I... | Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ... | Q1BSL3 |
Q6A6N5 | RS17_CUTAK | 30S ribosomal protein S17 | Cutibacterium | <M><S><E><N><T><A><E><R><T><T><R><R><K><V><R><E><G><L><V><V><S><D><K><M><N><K><T><I><T><V><M><V><E><D><R><V><K><H><P><L><Y><G><K><V><M><T><K><S><V><R><L><K><A><H><D><E><N><N><E><A><G><M><G><D><R><V><R><I><M><E><T><R><P><L><S><A><T><K><R><W><R><L><V><E><I><I><E><K><A><K> | One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.<BOP> | Q6A6N5 |
Q31RS8 | NTPP_SYNE7 | Nucleotide pyrophosphatase | Synechococcus | <M><T><T><P><R><L><I><L><A><S><A><S><P><A><R><R><R><L><L><A><T><V><G><L><T><V><E><V><Q><P><S><H><F><D><E><S><L><V><Q><L><N><D><P><P><A><L><V><Q><E><L><A><F><R><K><A><A><S><V><A><R><S><Q><T><E><P><A><L><V><L><G><C><D><S><V><L><A><I><N><G><E><I><C><G><K><P><A><S><P><A><E><A><I><A><R><W><Q><Q><M><R><G><Q><W><G><E><L><H><T... | Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.<BOP> | Q31RS8 |
O07515 | TRPP_BACSU | Probable tryptophan transport protein | Bacillus | <M><K><T><K><E><L><V><I><M><A><L><F><A><A><I><G><A><A><L><H><S><I><I><P><P><F><L><G><G><M><K><P><D><M><M><L><I><M><M><F><M><G><I><L><L><F><P><R><V><Q><N><V><L><V><I><G><I><V><T><G><I><I><S><A><L><T><T><A><F><P><A><G><Q><I><P><N><I><I><D><K><P><V><S><A><F><L><F><F><S><L><F><L><L><F><R><K><S><R><K><T><G><A><A><A><V><L><T... | Probably involved in tryptophan uptake.<BOP> | O07515 |
Q12040 | YO283_YEAST | Broad-specificity phosphatase YOR283W | Saccharomyces | <M><T><K><E><V><P><Y><Y><C><D><N><D><D><N><N><I><I><R><L><F><I><I><R><H><G><Q><T><E><H><N><V><K><K><I><L><Q><G><H><K><D><T><S><I><N><P><T><G><E><E><Q><A><T><K><L><G><H><Y><L><R><S><R><G><I><H><F><D><K><V><V><S><S><D><L><K><R><C><R><Q><T><T><A><L><V><L><K><H><S><K><Q><E><N><V><P><T><S><Y><T><S><G><L><R><E><R><Y><M><G><V... | Metal-independent phosphatase active against a broad range of phosphorylated substrates including nucleoside tri- and diphosphates, phosphorylated organic acids, and amino acids. Shows no activity against phytic acid, phosphorylated carbohydrates, and nucleoside monophosphates.<BOP> | Q12040 |
B1YRB8 | RL11_BURA4 | 50S ribosomal protein L11 | Burkholderia cepacia complex | <M><A><K><K><I><V><G><F><I><K><L><Q><I><P><A><G><K><A><N><P><S><P><P><V><G><P><A><L><G><Q><R><G><L><N><I><M><E><F><C><K><A><F><N><A><Q><T><Q><G><M><E><P><G><L><P><V><P><V><V><I><T><A><F><A><D><K><S><F><T><F><V><M><K><T><P><P><A><T><V><L><I><K><K><A><A><K><V><D><K><G><S><S><K><P><H><T><D><K><V><G><S><I><T><R><A><Q><A><E... | Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.<BOP> | B1YRB8 |
Q65DX4 | ATPB_BACLD | F-ATPase subunit beta | Bacillus | <M><K><K><G><R><V><S><Q><V><L><G><P><V><V><D><V><R><F><E><D><G><H><L><P><E><I><Y><N><A><I><K><V><T><H><K><A><Q><N><E><N><E><V><D><I><D><L><T><L><E><V><A><L><H><L><G><D><D><S><V><R><T><I><A><M><A><S><T><D><G><V><T><R><G><M><E><A><I><D><L><G><E><P><I><S><V><P><V><G><N><V><T><L><G><R><V><F><N><V><L><G><E><N><I><D><L><D><E... | Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.<BOP> | Q65DX4 |
B3ESB4 | GREA_AMOA5 | Transcript cleavage factor GreA | Candidatus Amoebophilus | <M><E><K><V><S><Y><Y><T><E><E><G><L><Q><R><L><K><G><E><L><T><Q><L><K><S><E><G><R><A><K><V><A><E><Q><L><S><E><A><R><D><K><G><D><L><S><E><N><A><E><Y><D><A><A><K><E><A><Q><E><I><L><E><R><R><I><A><K><L><E><E><L><M><I><N><A><R><V><I><N><K><D><N><I><N><T><S><A><V><S><I><L><S><K><V><K><I><K><N><K><K><L><G><K><V><S><T><Y><T><M... | Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factor... | B3ESB4 |
A1APT3 | PLSX_PELPD | Phosphate-acyl-ACP acyltransferase | Pelobacter | <M><R><I><A><V><D><A><M><G><G><D><N><A><P><T><I><E><V><E><G><A><V><A><A><C><R><E><F><G><I><P><I><T><L><V><G><D><Q><E><R><L><R><K><E><L><E><L><H><H><C><S><G><L><D><I><D><I><F><H><A><S><E><V><V><G><M><H><D><S><A><S><D><A><I><R><R><K><K><N><S><S><V><R><L><A><F><E><L><V><K><E><G><K><A><C><A><A><V><S><A><G><N><S><G><A><T><M... | Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.<BOP> | A1APT3 |
A0LRF2 | HEM1_ACIC1 | Glutamyl-tRNA reductase | Acidothermus | <M><S><L><L><V><V><G><V><S><H><R><G><T><P><L><S><L><L><E><R><A><V><L><D><S><D><Q><A><T><K><L><L><D><D><L><V><G><S><P><V><V><R><E><G><M><V><L><S><T><C><N><R><V><E><I><Y><A><C><V><E><K><F><H><P><A><L><T><L><I><S><E><L><L><S><R><H><G><N><V><N><F><D><E><I><A><G><H><V><H><V><H><Y><D><D><R><A><V><Q><H><L><F><A><V><A><A><G><L... | Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).<BOP> | A0LRF2 |
Q4L945 | PTG3C_STAHJ | PTS system glucose-specific EIIA component | Staphylococcus | <M><F><K><K><L><F><G><Q><L><Q><R><I><G><K><A><L><M><L><P><V><A><I><L><P><A><A><G><L><L><L><A><I><G><T><A><F><Q><G><E><A><L><Q><Q><Y><L><P><F><I><K><N><G><V><I><Q><N><I><A><N><M><M><T><G><A><G><G><I><I><F><D><N><L><P><I><I><F><A><L><G><V><A><I><G><L><A><G><G><D><G><V><A><A><I><A><A><F><V><G><F><I><I><M><N><K><T><M><G><A... | The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in glucose transport.<BOP> | Q4L945 |
B8DVS6 | IXTPA_BIFA0 | Nucleoside-triphosphate pyrophosphatase | Bifidobacterium | <M><N><I><V><V><A><T><H><N><E><G><K><L><V><E><I><R><D><I><L><A><E><E><F><G><D><G><A><H><D><I><E><L><V><S><A><G><S><L><G><L><P><D><P><V><E><T><G><I><T><F><E><A><N><A><L><L><K><A><R><F><V><A><R><L><T><G><L><P><A><I><A><D><D><S><G><L><I><V><D><V><M><G><N><A><P><G><I><L><S><A><R><W><A><G><E><H><G><N><D><A><A><N><I><D><L><L... | Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical p... | B8DVS6 |
Q0A8J8 | RLMM_ALKEH | 23S rRNA 2'-O-ribose methyltransferase RlmM | Alkalilimnicola | <M><T><E><R><D><P><I><P><T><R><H><A><T><R><W><L><L><Q><C><R><P><G><F><G><A><D><L><A><A><E><L><A><A><W><S><S><D><A><G><V><A><G><W><P><R><V><E><N><D><Q><G><R><V><D><F><H><S><A><D><G><R><P><L><P><T><P><P><A><L><T><F><A><R><Q><A><W><P><V><V><A><D><C><P><Q><L><P><E><R><D><R><V><G><A><L><L><E><A><L><A><P><H><L><P><E><A><L><A... | Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.<BOP> | Q0A8J8 |
P33318 | IF3_KLEPN | Translation initiation factor IF-3 | Klebsiella | <M><K><G><G><K><R><V><Q><T><A><R><P><N><R><I><N><G><E><I><R><A><Q><E><V><R><L><T><G><L><E><G><E><Q><L><G><I><V><S><L><R><E><A><I><E><K><A><E><E><A><G><V><D><L><V><E><I><S><P><N><A><E><P><P><V><C><R><I><M><D><Y><G><K><F><L><Y><E><K><S><K><S><S><K><E><Q><K><K><K><Q><K><V><I><Q><V><K><E><I><K><F><R><P><G><T><D><E><G><D><Y... | IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.<BOP> | P33318 |
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