accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
Q9H5Z1
DHX35_HUMAN
DEAH box protein 35
Homo
<M><A><A><P><V><G><P><V><K><F><W><R><P><G><T><E><G><P><G><V><S><I><S><E><E><R><Q><S><L><A><E><N><S><G><T><T><V><V><Y><N><P><Y><A><A><L><S><I><E><Q><Q><R><Q><K><L><P><V><F><K><L><R><N><H><I><L><Y><L><I><E><N><Y><Q><T><V><V><I><V><G><E><T><G><C><G><K><S><T><Q><I><P><Q><Y><L><A><E><A><G><W><T><A><E><G><R><V><V><G><V><T><Q...
May be involved in pre-mRNA splicing.<BOP>
Q9H5Z1
Q98B89
PYRD_RHILO
Dihydroorotate oxidase
Mesorhizobium
<M><S><V><L><D><R><L><G><Q><K><L><L><F><A><F><D><P><E><T><A><H><G><L><S><I><A><A><L><R><C><G><L><P><A><G><T><R><A><V><R><D><I><R><L><K><V><S><L><C><G><L><D><F><P><N><P><L><G><M><A><A><G><Y><D><K><D><A><E><V><P><D><A><L><L><G><L><G><F><G><F><A><E><V><G><T><V><T><P><L><P><Q><A><G><N><P><K><P><R><I><F><R><L><T><A><D><E><A...
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.<BOP>
Q98B89
B1JLQ0
LSRA_YERPY
Autoinducer 2 import ATP-binding protein LsrA
Yersinia
<M><P><H><T><V><A><T><P><P><P><L><L><Q><V><R><G><I><S><K><Q><F><S><G><V><V><V><L><K><S><I><D><F><T><L><Q><P><G><Q><V><H><A><L><L><G><G><N><G><A><G><K><S><T><L><M><K><I><I><A><G><I><L><P><P><D><T><G><V><I><E><M><N><G><Q><P><C><F><N><L><T><P><A><K><A><H><Q><L><G><I><Y><L><V><P><Q><E><P><M><L><F><A><N><L><S><V><Q><E><N><I...
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system.<BOP>
B1JLQ0
Q9PE66
RL14_XYLFA
50S ribosomal protein L14
Xylella
<M><I><Q><M><Q><S><Y><L><G><V><A><D><N><S><G><A><K><E><V><M><C><I><K><V><L><G><G><S><K><R><R><Y><A><S><I><G><D><I><I><K><V><T><V><K><E><A><I><P><R><G><K><V><K><K><G><E><V><Y><D><A><V><V><V><R><T><R><S><G><V><R><R><P><D><G><S><L><I><R><F><D><G><N><A><A><V><L><L><N><N><K><Q><E><P><I><G><T><R><V><F><G><P><V><T><R><E><L><R...
Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.<BOP>
Q9PE66
B4TES7
TRHO_SALHS
tRNA hydroxylation protein O
Salmonella
<M><P><V><L><H><N><R><I><S><N><D><E><L><K><A><K><M><L><A><E><S><E><P><R><T><T><I><S><F><Y><K><Y><F><T><I><A><S><P><Q><Q><T><R><D><A><L><Y><Q><V><F><T><A><L><D><V><F><G><R><V><Y><L><A><H><E><G><I><N><A><Q><I><S><V><P><Q><S><K><V><E><T><F><R><Q><Q><L><Y><T><F><D><P><A><L><D><G><V><R><L><N><I><A><L><E><D><D><G><K><S><F><W...
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.<BOP>
B4TES7
B7NSA0
MNTP_ECO7I
Probable manganese efflux pump MntP
Escherichia
<M><N><I><T><A><T><V><L><L><A><F><G><M><S><M><D><A><F><A><A><S><I><G><K><G><A><T><L><H><K><P><K><F><S><E><A><L><R><T><G><L><I><F><G><A><V><E><T><L><T><P><L><I><G><W><G><M><G><M><L><A><S><R><F><V><L><E><W><N><H><W><I><A><F><V><L><L><I><F><L><G><G><R><M><I><I><E><G><F><R><G><P><D><D><E><D><E><E><P><R><R><R><H><G><F><W><L...
Probably functions as a manganese efflux pump.<BOP>
B7NSA0
B2UYY8
REX_CLOBA
Redox-sensing transcriptional repressor Rex
Clostridium
<M><D><K><N><K><N><I><S><M><A><V><I><K><R><L><P><K><Y><H><R><Y><L><N><E><L><M><K><N><D><V><D><R><I><S><S><K><E><L><G><E><K><I><G><F><T><A><S><Q><I><R><Q><D><L><N><C><F><G><D><F><G><Q><Q><G><Y><G><Y><N><V><K><E><L><Y><T><Q><I><N><S><I><L><G><L><D><K><E><Y><N><A><V><L><I><G><A><G><N><I><G><Q><A><I><A><N><Y><S><R><F><D><K...
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.<BOP>
B2UYY8
A7HM70
NRDR_FERNB
Transcriptional repressor NrdR
Fervidobacterium
<M><R><C><P><F><C><G><Y><E><D><T><R><V><L><D><S><R><E><L><S><E><G><R><A><I><R><R><R><R><E><C><P><Q><C><H><A><R><F><T><T><Y><E><R><Y><E><T><G><P><I><T><V><I><K><K><D><G><R><R><E><K><F><D><R><K><K><I><L><N><G><L><L><K><A><F><E><K><R><P><I><T><V><D><D><M><E><R><I><V><D><N><I><V><S><Q><L><Q><K><S><G><T><L><E><V><P><S><E><L...
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.<BOP>
A7HM70
C8VQ98
AUSM_EMENI
Austinoid biosynthesis clusters protein M
Aspergillus subgen. Nidulantes
<M><S><D><T><P><T><R><K><T><D><L><R><V><I><I><V><G><G><S><V><A><G><L><T><L><A><H><C><L><A><N><A><N><I><D><H><I><V><L><E><K><R><A><E><I><S><P><Q><E><G><A><F><L><G><I><W><P><N><G><G><R><I><F><D><Q><L><G><V><Y><A><D><L><E><K><C><T><V><P><I><H><K><M><R><V><R><F><P><D><G><V><S><F><S><S><E><L><P><R><Q><V><Q><E><R><F><G><Y><P...
FAD-dependent monooxygenase; part of the gene cluster B that mediates the biosynthesis of austinol and dehydroaustinol, two fungal meroterpenoids . The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA . 3,5-dimethylorsellinic acid is then prenylated by the polypr...
C8VQ98
Q4ZHV7
BGALA_ASPPH
Lactase A
Aspergillus
<M><K><L><S><S><A><C><A><I><A><L><L><A><A><Q><A><A><G><A><S><I><K><H><R><I><N><G><F><T><L><T><E><H><S><D><P><A><K><R><E><L><L><Q><K><Y><V><T><W><D><D><K><S><L><F><I><N><G><E><R><I><M><I><F><S><G><E><F><H><P><F><R><L><P><V><K><E><L><Q><L><D><I><F><Q><K><V><K><A><L><G><F><N><C><V><S><F><Y><V><D><W><A><L><V><E><G><E><P><G...
Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.<BOP>
Q4ZHV7
Q31IX9
RL2_HYDCU
50S ribosomal protein L2
Hydrogenovibrio
<M><A><I><I><K><K><S><K><P><T><S><P><G><R><R><F><V><V><S><V><V><E><P><D><L><H><K><G><K><P><F><S><A><L><L><E><K><K><S><K><S><G><G><R><N><S><N><G><R><I><T><V><R><H><Q><G><G><G><H><K><Q><H><Y><R><Q><I><D><F><K><R><N><K><D><G><V><A><A><V><V><E><R><L><E><Y><D><P><N><R><T><A><H><I><A><L><L><K><Y><A><D><G><E><R><R><Y><I><L><A...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
Q31IX9
A9N944
LEPA_COXBR
Ribosomal back-translocase LepA
Coxiella
<M><T><T><I><S><Q><K><F><I><R><N><F><S><I><I><A><H><I><D><H><G><K><S><T><L><A><D><R><F><I><Q><L><C><G><G><L><S><E><R><E><M><K><A><Q><V><L><D><S><M><D><I><E><R><E><R><G><I><T><I><K><A><Q><S><V><T><L><N><F><K><S><Q><D><G><H><F><Y><Q><L><N><F><I><D><T><P><G><H><V><D><F><S><Y><E><V><S><R><S><L><A><A><C><E><G><A><L><L><V><V...
Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-t...
A9N944
Q0V8C2
EXOC3_BOVIN
Exocyst complex component Sec6
Bos
<M><K><E><T><D><R><E><A><V><A><T><A><V><Q><R><V><A><G><M><L><Q><R><P><D><Q><L><D><K><V><E><Q><Y><R><R><R><E><A><R><K><K><A><S><V><E><A><R><L><K><A><A><I><Q><S><Q><L><D><G><V><R><T><G><L><S><Q><L><H><N><A><L><N><D><V><K><D><I><Q><Q><S><L><A><D><V><S><K><D><W><R><Q><S><I><N><T><I><E><S><L><K><D><V><K><D><A><V><V><R><H><S...
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.<BOP>
Q0V8C2
Q21W43
BIOB_ALBFT
Biotin synthase
Rhodoferax
<M><S><P><N><P><S><Q><Q><S><S><A><V><A><F><H><P><S><A><A><P><I><T><L><P><E><S><A><T><W><P><L><A><D><V><L><A><L><F><E><L><P><F><N><D><L><M><F><Q><A><Q><Q><T><H><R><A><H><F><P><K><G><D><V><E><L><A><T><L><L><S><I><K><T><G><G><C><E><E><D><C><S><Y><C><P><Q><A><A><R><Y><D><T><G><V><E><A><Q><K><I><L><E><L><E><Q><V><L><D><A><A...
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.<BOP>
Q21W43
Q29529
CBR2_PIG
NADPH-dependent carbonyl reductase 2
Sus
<M><Q><M><N><F><S><G><L><R><A><L><V><T><G><A><G><K><G><I><G><R><D><T><V><K><A><L><H><V><S><G><A><R><V><V><A><V><T><R><T><N><G><D><L><V><S><L><S><Q><E><C><P><G><I><E><P><V><C><V><D><L><G><D><W><E><A><T><E><R><A><L><G><G><V><G><P><V><D><L><L><V><N><N><A><A><V><A><L><M><Q><P><F><L><D><T><T><K><E><V><F><D><R><S><F><N><V><N...
May function in the pulmonary metabolism of endogenous carbonyl compounds, such as aliphatic aldehydes and ketones derived from lipid peroxidation, 3-ketosteroids and fatty aldehydes, as well as in xenobiotic metabolism.<BOP>
Q29529
A4IR80
SYA_GEOTN
Alanyl-tRNA synthetase
Geobacillus
<M><K><K><L><T><S><A><E><V><R><R><M><F><L><Q><F><F><Q><E><K><G><H><A><V><E><P><S><A><S><L><I><P><V><D><D><P><S><L><L><W><I><N><S><G><V><A><T><L><K><K><Y><F><D><G><R><I><I><P><D><N><P><R><I><C><N><A><Q><K><S><I><R><T><N><D><I><E><N><V><G><K><T><A><R><H><H><T><F><F><E><M><L><G><N><F><S><I><G><D><Y><F><K><R><E><A><I><H><W...
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.<BOP>
A4IR80
G3MIX6
E1181_AMBMU
Evasin P1181
Amblyomma
<M><A><L><N><W><S><F><R><V><I><F><V><S><A><M><W><C><A><L><L><K><F><A><T><L><E><E><R><E><D><D><N><D><Y><G><G><G><C><P><F><V><V><L><G><N><G><T><H><A><K><P><A><G><C><S><H><L><C><N><G><A><P><E><T><L><D><N><I><E><C><Y><N><V><T><E><E><V><A><K><R><M><T><P><D><I><P><Y><T><C><W><L><G><W><C><S><K><G><E><C><K><R><D><N><R><T><E><V...
Salivary chemokine-binding protein which binds to host chemokines CCL3 and CCL4.<BOP>
G3MIX6
A5CSW0
THIM_CLAM3
4-methyl-5-beta-hydroxyethylthiazole kinase
Clavibacter
<M><S><A><A><R><P><S><A><H><E><T><T><G><T><G><T><A><S><A><D><L><L><L><L><L><R><E><R><Q><P><L><V><Q><C><I><T><N><A><V><V><T><G><F><T><A><N><V><L><L><A><L><G><A><A><P><A><M><T><D><V><P><T><E><A><G><P><F><A><R><I><A><S><G><L><L><V><N><L><G><T><P><H><A><E><Q><R><E><A><A><V><E><A><A><H><A><A><R><E><A><G><T><P><W><V><L><D><P...
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).<BOP>
A5CSW0
Q2V2G5
SCPRP_OCTVU
Small cardioactive peptide-related peptide
Octopus
<M><F><C><K><H><L><S><F><V><A><I><T><I><C><F><L><L><V><L><A><K><T><E><N><E><I><Q><Q><K><N><I><K><F><D><Q><R><T><W><R><N><M><R><S><N><G><Y><L><A><L><P><R><Q><G><R><S><D><N><Q><P><D><Y><T><C><C><G><M><P><L><T><K><Y><V><G><I><C><P><I><G><M><E><C><C><P><G><L><K><K><V><L><Q><K><S><G><Q><R><T><I><Y><S><V><C><V><A><D><A><Y>
Evokes contractions in the radula protractor muscle, and may regulate feeding behavior and gut motility by controlling muscle contraction of the buccal mass.<BOP>
Q2V2G5
Q8MIC2
TF2LX_PAPHA
TGIF-like on the X
Papio
<M><E><A><A><A><D><S><P><A><E><T><R><S><R><V><E><K><D><S><R><R><V><E><K><D><S><R><R><P><K><K><D><S><P><A><K><T><Q><S><P><A><Q><D><T><S><I><M><L><R><N><N><A><D><T><G><K><V><L><A><L><P><E><H><K><K><K><R><K><G><Y><L><P><A><E><S><V><K><I><L><R><R><W><M><Y><K><H><R><F><R><A><Y><P><S><E><A><E><K><R><M><L><S><K><K><T><N><L><S...
May have a transcription role in testis.<BOP>
Q8MIC2
P19323
FHLA_ECOLI
Formate hydrogenlyase transcriptional activator FhlA
Escherichia
<M><S><Y><T><P><M><S><D><L><G><Q><Q><G><L><F><D><I><T><R><T><L><L><Q><Q><P><D><L><A><S><L><C><E><A><L><S><Q><L><V><K><R><S><A><L><A><D><N><A><A><I><V><L><W><Q><A><Q><T><Q><R><A><S><Y><Y><A><S><R><E><K><D><T><P><I><K><Y><E><D><E><T><V><L><A><H><G><P><V><R><S><I><L><S><R><P><D><T><L><H><C><S><Y><E><E><F><C><E><T><W><P><Q...
Required for induction of expression of the formate dehydrogenase H and hydrogenase-3 structural genes. Also activates expression of hyf operon (encodes the silent hydrogenase-4 gene cluster) .<BOP>
P19323
Q5NTB3
FA11_BOVIN
Coagulation factor XIa light chain
Bos
<M><T><L><L><Y><Q><M><V><H><F><A><L><F><A><S><V><A><G><E><C><V><T><T><L><F><Q><D><A><C><F><K><G><G><D><I><T><V><A><F><A><P><N><A><K><H><C><Q><I><I><C><T><H><H><P><R><C><L><L><F><T><F><M><T><E><S><S><S><E><D><P><T><K><W><Y><T><C><I><L><K><D><S><V><T><E><T><L><P><M><V><N><M><T><G><A><I><S><G><Y><S><S><K><Q><C><L><H><H><I...
Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.<BOP>
Q5NTB3
P02173
MYG_ORCOR
Myoglobin
Orcinus
<M><G><L><S><D><G><E><W><Q><L><V><L><N><V><W><G><K><V><E><A><D><L><A><G><H><G><Q><D><I><L><I><R><L><F><K><G><H><P><E><T><L><E><K><F><D><K><F><K><H><L><K><T><E><A><D><M><K><A><S><E><D><L><K><K><H><G><N><T><V><L><T><A><L><G><A><I><L><K><K><K><G><H><H><D><A><E><L><K><P><L><A><Q><S><H><A><T><K><H><K><I><P><I><K><Y><L><E><F...
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.<BOP>
P02173
Q03EN8
THII_PEDPA
tRNA 4-thiouridine synthase
Pediococcus
<M><K><Y><T><E><I><M><V><R><Y><G><E><L><S><T><K><G><K><N><R><K><D><F><I><A><R><L><G><G><N><I><R><K><S><L><K><D><F><E><D><V><E><I><H><P><N><R><D><R><T><H><V><T><L><N><G><T><D><S><D><A><V><I><N><R><L><K><K><V><F><G><I><Q><N><F><S><P><M><L><K><V><E><K><T><M><E><A><V><Q><A><G><A><L><E><M><M><K><E><Q><L><K><P><G><M><T><F><K...
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt...
Q03EN8
Q01662
MAP1_YEAST
Peptidase M 1
Saccharomyces
<M><S><T><A><T><T><T><V><T><T><S><D><Q><A><S><H><P><T><K><I><Y><C><S><G><L><Q><C><G><R><E><T><S><S><Q><M><K><C><P><V><C><L><K><Q><G><I><V><S><I><F><C><D><T><S><C><Y><E><N><N><Y><K><A><H><K><A><L><H><N><A><K><D><G><L><E><G><A><Y><D><P><F><P><K><F><K><Y><S><G><K><V><K><A><S><Y><P><L><T><P><R><R><Y><V><P><E><D><I><P><K><P...
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Plays the major role in N-terminal methionine removal. Less efficient when the second ...
Q01662
C4Z157
EFP_LACE2
Elongation factor P
Lachnospira
<M><V><D><A><G><S><F><K><N><G><I><T><I><Q><Y><E><N><G><I><W><Q><V><I><E><F><Q><H><V><K><P><G><K><G><S><P><F><V><R><A><K><L><K><N><I><I><S><G><G><V><I><E><N><S><F><R><P><T><E><K><F><D><L><A><H><I><D><R><S><E><Y><Q><Y><L><Y><A><D><G><D><L><Y><N><F><M><N><T><E><T><Y><D><Q><I><A><L><S><A><D><Q><V><G><D><S><L><K><F><V><K><E...
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.<BOP>
C4Z157
Q5DRC8
PCDB6_PANTR
Protocadherin beta-6
Pan
<M><M><Q><T><K><V><Q><N><K><K><R><Q><V><A><F><F><I><L><L><M><L><W><G><E><V><G><S><E><S><I><Q><Y><S><V><L><E><E><T><E><S><G><T><F><V><A><N><L><T><K><D><L><G><L><R><V><G><E><L><A><S><R><G><A><R><V><V><F><K><G><N><R><Q><H><L><Q><F><D><P><Q><T><H><D><L><L><L><N><E><K><L><D><R><E><E><L><C><G><S><T><E><L><C><V><L><P><F><Q><V...
Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination. Thereby, it is involved in the establishment and maintenance of specific neuronal connections in the brain.<BOP>
Q5DRC8
A4QLV6
RK20_NASOF
50S ribosomal protein L20, chloroplastic
Nasturtium
<M><T><R><I><K><R><G><Y><I><A><R><R><R><R><T><K><L><R><L><F><A><S><S><F><R><G><A><H><S><R><L><T><R><T><M><T><Q><Q><R><I><R><A><L><V><S><A><H><R><D><R><G><K><R><K><R><D><F><R><R><L><W><I><T><R><I><N><A><V><I><H><E><M><G><V><F><Y><S><Y><N><R><F><I><H><N><L><Y><K><K><Q><L><L><L><N><R><K><I><L><A><Q><I><A><L><L><N><R><S><C...
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.<BOP>
A4QLV6
P59379
RS11_THEVB
30S ribosomal protein S11
Thermosynechococcus
<M><A><P><S><A><K><R><S><G><P><R><K><Q><K><R><N><V><P><S><G><V><A><H><I><Q><S><T><F><N><N><T><I><V><S><I><T><D><P><N><G><E><V><I><A><W><A><S><A><G><S><S><G><F><K><G><A><K><K><G><T><P><F><A><A><Q><T><A><A><D><N><A><A><R><R><A><I><D><Q><G><M><R><Q><I><E><V><M><V><S><G><P><G><S><G><R><E><T><A><I><R><A><L><Q><A><A><G><L><E...
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.<BOP>
P59379
P40544
YKE4_YEAST
Zinc transporter YKE4
Saccharomyces
<M><K><A><S><H><I><C><S><Y><L><L><S><I><A><P><L><V><V><S><H><G><V><H><H><N><R><D><H><G><H><E><A><N><H><E><S><K><Q><S><F><L><I><L><K><Q><E><S><I><F><Y><S><L><V><C><F><L><Q><N><H><L><F><V><L><G><P><R><Y><N><A><I><V><A><I><L><I><I><Q><L><M><P><C><L><F><V><L><F><V><P><G><L><R><K><N><D><R><A><S><L><T><L><S><L><L><V><S><F><S...
Zinc transporter whose role depends on the zinc status of the cells. It helps to balance zinc levels between the cytosol and the secretory pathway. It transports zinc into the secretory pathway in a zinc-adequate environment and in a high zinc medium. In high zinc medium, transport of zinc into the secretory pathway is...
P40544
P0DPK6
SPVIS_STRVB
Spiroviolene synthase
Streptomyces
<M><T><V><N><E><I><D><L><P><P><I><F><C><P><L><E><S><A><R><H><P><R><A><H><L><V><D><E><R><A><R><E><W><I><R><T><S><P><M><C><T><T><D><E><E><R><T><W><V><A><A><S><C><S><T><D><F><F><A><R><F><A><P><D><A><A><T><D><D><R><L><L><W><T><S><L><W><V><Y><W><G><F><A><F><D><D><H><R><C><D><N><G><P><F><S><N><R><P><A><A><F><S><A><L><A><G><R...
Catalyzes the formation of (3R,6R,10S,11R,14R)-spiroviolene from geranylgeranyl diphosphate (GGPP) via a 1,11-cyclization and a 10Re,14Si-cyclization.<BOP>
P0DPK6
Q8BQZ4
RLGPB_MOUSE
p170
Mus
<M><Y><S><E><W><R><S><L><H><L><V><I><Q><S><D><Q><G><H><T><S><V><L><H><S><Y><P><E><S><V><G><R><E><V><A><N><A><V><V><R><P><L><G><Q><A><L><G><T><S><S><V><A><G><S><E><S><L><L><K><T><D><K><E><V><K><W><T><M><E><V><I><C><Y><G><L><T><L><P><L><D><G><E><T><V><K><Y><C><V><D><V><Y><T><D><W><I><M><A><L><V><L><P><K><D><S><I><P><L><P...
Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators for the Ras-like small GTPases RALA and RALB.<BOP>
Q8BQZ4
P52981
GLGB_SYNY3
Glycogen branching enzyme
unclassified Synechocystis
<M><T><Y><T><I><N><A><D><Q><V><H><Q><I><V><H><N><L><H><H><D><P><F><E><V><L><G><C><H><P><L><G><D><H><G><K><V><N><Q><W><V><I><R><A><Y><L><P><T><A><E><A><V><T><V><L><L><P><T><D><R><R><E><V><I><M><T><T><V><H><H><P><N><F><F><E><C><V><L><E><L><E><E><P><K><N><Y><Q><L><R><I><T><E><N><G><H><E><R><V><I><Y><D><P><Y><G><F><K><T><P...
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.<BOP>
P52981
Q65ZZ3
OBG_BORGP
GTP-binding protein Obg
Borreliella
<M><Y><N><F><K><D><S><V><S><I><T><V><I><S><G><N><G><G><S><G><C><V><S><F><L><R><E><K><F><N><A><K><G><G><P><D><G><G><N><G><G><S><G><G><S><V><I><F><K><V><K><E><N><L><R><T><L><S><S><Y><K><N><G><H><V><L><C><A><K><N><G><R><P><G><M><S><F><K><R><S><G><A><N><G><K><D><L><I><L><F><V><P><P><N><T><D><I><Y><N><E><N><D><E><A><L><L><C...
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B...
Q65ZZ3
Q5ZLC8
ANR52_CHICK
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
Gallus
<M><G><I><L><S><I><T><D><Q><P><P><L><V><Q><A><I><F><N><R><D><V><E><E><V><R><S><L><L><N><Q><K><E><N><I><N><V><L><D><Q><E><R><R><T><P><L><H><T><A><A><Y><I><G><D><V><A><I><L><E><L><L><I><L><S><G><A><N><V><N><A><K><D><T><V><W><L><T><P><L><H><R><A><A><A><S><R><N><E><K><A><L><H><L><L><L><K><H><S><A><D><V><N><A><R><D><K><Y><W...
Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates.<BOP>
Q5ZLC8
Q08484
GYP1_YEAST
GAP for YPT1
Saccharomyces
<M><G><V><R><S><A><A><K><E><M><H><E><R><D><H><N><S><D><S><S><S><L><V><T><S><L><M><K><S><W><R><I><S><S><A><S><S><S><K><K><P><S><L><Y><K><M><N><T><T><E><S><T><S><L><P><S><G><Y><A><S><S><A><D><R><D><R><R><T><S><D><G><N><F><E><A><M><A><K><Q><Q><A><S><T><R><R><T><S><N><S><Y><S><P><L><R><Y><V><N><P><T><L><S><T><A><S><N><E><S...
GTPase-activating protein (GAP) that stimulates specifically the intrinsic GTPase activity of Ypt/Rab-type GTPases YPT1 and YPT7 . Functions on the Golgi as a negative regulator of YPT1 . Functions on the vacuole as a negative regulator of YPT7 . It is also active on SEC4 and YPT51 . Provides a catalytic arginine (argi...
Q08484
Q54N97
DPOD1_DICDI
DNA polymerase III
Dictyostelium
<M><K><R><S><I><V><T><G><G><G><N><N><D><K><K><F><K><A><Q><P><P><P><K><N><N><Y><R><G><G><G><D><D><E><E><D><D><E><F><E><E><D><D><D><E><D><E><G><D><E><F><G><E><E><E><D><E><D><D><I><D><V><E><N><I><I><A><S><D><S><M><D><I><D><I><Q><D><D><G><S><Q><Q><L><F><L><W><S><R><K><P><V><Q><D><L><V><P><H><K><K><P><L><I><F><Q><Q><L><E><V...
Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.<BOP>
Q54N97
B2V2P4
KDPC_CLOBA
Potassium-translocating ATPase C chain
Clostridium
<M><K><E><F><K><A><V><F><P><K><A><L><I><I><F><I><I><F><T><I><L><C><G><G><I><Y><T><I><F><I><T><G><I><S><Q><L><I><F><P><K><Q><A><N><G><S><I><I><E><V><N><G><K><K><Y><G><S><V><L><L><A><Q><Q><Y><N><D><E><K><H><L><W><G><R><I><M><N><I><D><T><N><T><F><V><D><E><N><G><K><K><L><A><Y><S><A><P><S><N><L><S><P><A><S><K><E><Y><E><A><L...
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation...
B2V2P4
Q1BXD0
RLME_BURCA
rRNA (uridine-2'-O-)-methyltransferase
Burkholderia cepacia complex
<M><A><K><N><R><F><N><Q><H><W><L><H><D><H><I><N><D><P><Y><V><K><M><A><Q><R><E><G><Y><R><A><R><A><A><Y><K><L><K><E><I><D><E><Q><D><K><L><I><R><P><G><Q><V><I><V><D><L><G><A><T><P><G><S><W><S><Q><Y><A><R><N><K><L><A><Q><G><K><K><R><D><A><E><R><E><G><G><I><D><G><T><I><V><A><L><D><I><L><P><M><E><P><I><A><D><V><H><F><L><Q><G...
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.<BOP>
Q1BXD0
B3E3Z0
RSMH_TRIL1
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Trichlorobacter
<M><E><E><F><H><H><L><S><V><L><A><R><E><V><M><E><Q><L><A><P><R><P><G><G><T><Y><L><D><G><T><L><G><G><G><G><H><S><E><L><I><L><E><K><I><G><P><D><G><L><L><I><G><I><D><R><D><P><A><A><L><A><A><A><S><E><R><L><R><R><F><G><S><C><F><R><P><L><Q><G><S><F><G><D><L><A><E><L><L><K><Q><E><G><I><N><T><L><D><G><L><L><L><D><L><G><V><S><S...
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.<BOP>
B3E3Z0
Q03CW1
DAPH_LACP3
Tetrahydrodipicolinate N-acetyltransferase
Lacticaseibacillus
<M><A><Q><L><D><T><Q><K><I><I><S><T><I><A><N><S><K><K><T><T><P><V><K><V><Y><L><K><G><K><L><S><E><L><H><F><P><K><S><V><H><A><F><I><G><K><H><T><G><T><V><I><G><D><W><A><E><I><K><P><I><L><K><K><A><K><L><D><D><Y><Y><V><E><T><A><G><R><N><T><G><V><P><L><L><D><I><K><A><A><N><A><R><I><E><P><G><A><I><I><R><D><Q><V><L><I><G><D><N...
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.<BOP>
Q03CW1
Q2W6V3
RF1_MAGSA
Peptide chain release factor 1
Magnetospirillum
<M><N><L><E><T><Q><F><D><K><V><L><Y><R><H><D><E><V><R><A><Q><L><S><S><G><E><G><M><D><S><Q><T><I><Q><R><L><S><K><E><L><S><E><L><D><P><V><V><T><A><V><Q><A><F><R><K><A><R><E><D><M><V><Q><A><A><E><M><M><N><D><P><D><M><K><D><L><A><E><E><E><F><Y><A><L><K><E><R><L><P><A><L><E><R><E><V><Q><I><M><L><L><P><K><D><E><A><D><E><K><N...
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.<BOP>
Q2W6V3
B9EBI5
MUTL_MACCJ
DNA mismatch repair protein MutL
Macrococcus
<M><G><I><I><K><T><L><D><S><T><I><S><N><K><I><A><A><G><E><V><I><E><R><P><Q><S><V><V><K><E><L><V><E><N><A><I><D><A><K><S><T><S><I><T><I><E><V><E><E><A><G><L><S><K><I><K><V><T><D><N><G><S><G><I><L><E><E><D><L><E><L><M><F><R><R><H><A><T><S><K><I><E><N><E><H><D><L><F><H><I><R><S><L><G><F><R><G><E><A><L><A><S><I><A><S><V><S...
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part ...
B9EBI5
Q9GLG7
CAN3_MACFA
Muscle-specific calcium-activated neutral protease 3
Macaca
<M><P><T><V><I><S><A><S><V><A><P><R><T><A><A><E><P><R><S><P><G><P><V><P><H><P><A><Q><S><K><A><T><E><A><G><G><G><N><A><S><G><I><Y><S><A><I><I><S><R><N><F><P><I><I><G><V><K><E><K><T><F><E><Q><L><H><K><K><C><L><E><K><K><V><L><Y><V><D><P><E><F><P><P><D><E><T><S><L><F><Y><S><Q><K><F><P><I><Q><F><I><W><K><R><P><P><E><I><C><E...
Calcium-regulated non-lysosomal thiol-protease. Proteolytically cleaves CTBP1. Mediates, with UTP25, the proteasome-independent degradation of p53/TP53.<BOP>
Q9GLG7
A4IPB3
IOLC_GEOTN
2-deoxy-5-keto-D-gluconate kinase
Geobacillus
<M><N><L><L><P><F><D><E><Q><K><P><L><D><F><I><A><V><G><R><L><C><I><D><L><N><A><N><E><I><H><R><P><M><E><E><T><V><T><F><T><K><Y><V><G><G><S><P><A><N><I><A><I><G><M><A><R><L><G><M><K><T><G><F><I><G><R><V><A><D><D><Q><M><G><R><F><I><V><Q><Y><L><K><N><N><G><I><D><T><S><H><V><I><T><D><K><S><G><S><V><T><G><L><A><F><T><E><I><K...
Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D-gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP).<BOP>
A4IPB3
Q9CQC7
NDUB4_MOUSE
NADH-ubiquinone oxidoreductase B15 subunit
Mus
<M><S><G><S><K><Y><K><P><A><P><L><A><T><L><P><S><T><L><D><P><A><E><Y><D><V><S><P><E><T><R><R><A><Q><V><E><R><L><S><I><R><A><R><L><K><R><E><Y><L><L><Q><Y><N><D><P><K><R><V><S><H><I><E><D><P><A><L><I><R><W><T><Y><A><R><S><A><N><I><Y><P><N><F><R><P><T><P><K><N><S><L><L><G><A><V><A><G><F><G><P><L><I><F><W><Y><Y><V><F><K><T...
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.<BOP>
Q9CQC7
O83462
UPP_TREPA
UPRTase
Treponema
<M><E><G><Q><T><A><R><R><V><I><T><E><A><K><F><L><D><D><C><L><T><E><R><D><S><Y><Y><L><S><K><L><D><E><L><Y><S><S><A><M><S><S><F><A><Q><F><E><D><Q><Q><N><G><A><R><S><A><R><A><E><E><N><I><I><A><T><Y><D><S><I><G><N><L><M><Q><E><I><C><K><E><L><P><A><L><K><V><Y><S><F><E><T><Q><R><E><N><H><A><E><V><S><R><V><V><S><K><L><R><N><I...
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP>
O83462
Q5HQL4
MNHE1_STAEQ
Mnh complex subunit E1
Staphylococcus
<M><A><I><Q><F><V><I><N><L><L><V><S><V><I><W><L><L><V><T><N><S><Y><T><L><N><N><F><V><L><G><F><I><L><G><L><F><L><V><Y><L><L><H><R><V><L><P><G><Q><F><Y><L><V><R><I><Y><R><I><I><M><L><I><I><T><F><L><T><E><L><I><K><A><N><F><G><V><L><K><I><I><L><K><P><R><I><E><N><K><P><G><F><F><V><Y><E><T><E><L><E><R><D><W><Q><L><V><L><L><S...
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.<BOP>
Q5HQL4
Q5JDH2
RL2_THEKO
50S ribosomal protein L2
Thermococcus
<M><G><K><S><L><I><Q><Q><R><R><G><K><G><T><T><T><F><R><A><P><S><H><R><Y><R><G><A><V><R><Y><V><P><L><N><L><V><Q><E><R><T><L><R><G><V><V><E><E><I><L><H><D><P><G><R><T><A><P><V><A><R><V><K><F><E><D><G><T><K><K><L><I><I><A><P><E><G><V><L><V><G><Q><E><I><Y><I><G><P><E><A><P><I><A><I><G><N><T><L><P><L><A><K><I><P><E><G><T><Y...
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.<...
Q5JDH2
Q3TQB2
FXRD1_MOUSE
FAD-dependent oxidoreductase domain-containing protein 1
Mus
<M><F><R><R><A><L><R><L><G><L><G><P><G><L><P><Y><R><G><L><R><T><R><K><G><G><F><T><L><D><W><D><A><K><V><S><D><F><K><K><K><V><D><S><I><L><P><G><K><K><Y><E><V><L><Y><D><T><S><H><L><P><P><E><Q><A><D><V><V><I><I><G><G><G><I><L><G><L><S><V><A><F><W><L><K><K><L><E><S><R><R><G><A><I><R><V><L><V><V><E><Q><D><H><T><Y><S><R><A><S...
Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Involved in mid-late stages of complex I assembly.<BOP>
Q3TQB2
Q8DHQ2
COXX_THEVB
Heme O synthase
Thermosynechococcus
<M><T><F><L><A><R><L><S><S><S><T><G><D><L><S><T><K><L><V><D><Y><V><Q><L><T><K><P><R><L><I><L><L><F><L><I><T><T><A><A><A><M><E><V><A><G><Q><G><R><V><S><P><Q><L><L><L><I><T><L><G><S><G><T><C><A><A><A><A><A><N><T><I><N><C><L><Y><D><R><D><I><D><A><V><M><E><R><T><R><H><R><P><L><P><A><G><R><V><A><P><W><E><A><V><F><L><A><V><L...
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.<BOP>
Q8DHQ2
B7VL54
SELO_VIBA3
Protein adenylyltransferase SelO
Vibrio
<M><S><V><W><D><S><I><S><F><N><N><R><F><T><A><L><P><R><L><F><Y><T><P><I><Q><P><T><P><L><N><N><V><Q><W><L><A><W><N><H><N><L><A><N><E><L><G><F><P><S><F><E><C><T><S><E><E><L><L><E><T><L><S><G><N><V><E><P><E><Q><F><S><P><V><A><M><K><Y><A><G><H><Q><F><G><S><Y><N><P><D><L><G><D><G><R><G><L><L><L><A><Q><V><V><A><K><S><G><E><T...
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).<BOP>
B7VL54
Q2J2R7
ACCA_RHOP2
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Rhodopseudomonas
<M><S><E><P><M><R><S><Y><L><D><F><E><K><P><V><A><E><L><D><S><K><I><D><E><L><R><A><L><A><A><S><G><S><D><I><H><E><E><V><A><K><I><E><E><K><A><V><Q><A><L><N><E><L><Y><A><T><L><T><P><W><Q><K><T><Q><V><A><R><H><P><Q><R><P><H><C><V><D><Y><I><E><G><L><I><T><E><F><T><P><L><A><G><D><R><K><F><G><E><D><E><A><L><I><G><G><F><G><R><F...
Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.<BOP>
Q2J2R7
Q2RMD6
PFOR_MOOTA
Pyruvate synthase
Moorella
<M><P><K><Q><T><L><D><G><N><T><A><A><A><H><V><A><Y><A><M><S><E><V><A><T><I><Y><P><I><T><P><S><S><P><M><A><E><I><A><D><E><W><A><A><H><G><R><K><N><I><F><G><K><T><L><Q><V><A><E><M><Q><S><E><A><G><A><A><G><A><V><H><G><S><L><A><A><G><A><L><T><T><T><F><T><A><S><Q><G><L><L><L><M><I><P><N><M><Y><K><I><A><G><E><L><L><P><C><V><F...
Catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA and carbon dioxide. The two electrons that are generated as a result of pyruvate decarboxylation are used in the reduction of low potential ferredoxins, which provide reducing equivalents for central metabolism. Also catalyzes the reverse reaction, i.e. ...
Q2RMD6
E2RBS6
SETD3_CANLF
SET domain-containing protein 3
Canis
<M><G><K><K><S><R><V><K><T><Q><K><S><G><T><G><A><T><A><S><V><S><P><K><E><T><L><N><L><T><S><E><L><L><Q><K><C><S><S><P><A><P><G><P><G><K><E><W><E><E><Y><V><Q><I><R><S><L><V><E><K><I><R><K><K><Q><K><G><L><S><V><T><F><D><G><K><R><E><D><Y><F><P><D><L><M><K><W><A><S><E><N><G><A><S><V><E><G><F><E><M><V><N><F><K><E><E><G><F><G...
Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'. Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery. Does not have protein-lysine N-methyltransferase activity and proba...
E2RBS6
Q4V7W8
ETKMT_XENLA
Protein N-lysine methyltransferase METTL20
Xenopus
<M><L><R><T><A><R><F><L><Q><R><S><I><S><A><T><S><R><P><N><C><I><V><Q><P><Q><R><T><S><A><T><C><P><R><S><F><I><L><Q><H><T><E><A><T><S><D><P><L><T><P><E><I><R><L><R><L><L><T><P><R><C><D><F><W><R><Q><K><P><E><L><W><P><Y><G><D><P><Y><W><A><I><Y><W><P><G><G><Q><A><L><S><R><F><L><L><D><N><P><Q><I><V><R><G><G><R><V><L><D><L><G...
Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain.<BOP>
Q4V7W8
Q7NAV2
RS7_MYCGA
30S ribosomal protein S7
Mycoplasma
<M><R><K><N><R><A><E><K><R><K><V><L><P><D><P><V><Y><N><S><V><L><V><T><R><A><I><N><A><I><M><L><D><G><K><K><G><I><A><Q><K><I><L><Y><G><S><F><D><L><I><A><Q><K><T><Q><K><D><P><L><E><I><F><N><K><A><V><E><N><I><M><P><R><L><E><L><K><V><R><R><I><A><G><A><N><Y><Q><V><P><T><D><V><S><P><E><R><K><V><T><L><A><L><R><W><L><V><T><L><S...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.<BOP>
Q7NAV2
Q59072
SPSS_METJA
Sep-tRNA:Cys-tRNA synthase
Methanocaldococcus
<M><D><K><Y><K><N><L><T><R><S><L><T><R><E><F><I><N><L><N><P><I><Q><R><G><G><I><L><P><K><E><A><K><K><A><V><Y><E><Y><W><D><G><Y><S><V><C><D><Y><C><H><G><R><L><D><E><V><T><C><P><P><I><K><D><F><L><E><D><I><A><K><F><L><N><M><D><C><A><R><P><T><H><G><A><R><E><G><K><F><I><V><M><H><A><I><C><K><E><G><D><Y><V><V><L><D><K><N><A><H...
Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).<BOP>
Q59072
Q01473
RCAC_MICDP
Protein RcaC
Microchaete
<M><K><I><L><L><V><E><D><D><D><V><L><I><K><V><L><T><K><N><L><T><T><H><H><Y><I><V><D><V><V><K><D><G><E><M><G><W><T><Y><G><S><T><F><E><Y><D><L><I><I><L><D><I><M><L><P><N><L><D><G><I><S><L><C><K><R><F><R><A><Q><G><Y><T><V><P><I><L><L><L><T><A><Q><D><N><I><T><A><K><V><Q><G><L><D><A><G><A><D><D><Y><V><V><K><P><F><D><P><I><E...
Required for chromatic adaptation. Thought to be a positive regulator of phycobiliproteins.<BOP>
Q01473
B9E8A0
CH10_MACCJ
Chaperonin-10
Macrococcus
<M><L><K><P><Y><G><N><R><V><V><I><Q><K><T><E><R><E><T><T><T><A><S><G><I><V><L><T><D><S><A><K><E><K><T><N><E><G><T><V><V><A><V><G><T><G><R><I><L><N><N><G><E><R><V><E><I><G><V><S><V><G><D><R><V><V><Y><E><P><F><G><G><T><E><V><K><T><G><D><E><S><Y><I><V><L><K><E><E><D><I><I><A><I><V><E>
Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of ...
B9E8A0
O43293
DAPK3_HUMAN
Zipper-interacting protein kinase
Homo
<M><S><T><F><R><Q><E><D><V><E><D><H><Y><E><M><G><E><E><L><G><S><G><Q><F><A><I><V><R><K><C><R><Q><K><G><T><G><K><E><Y><A><A><K><F><I><K><K><R><R><L><S><S><S><R><R><G><V><S><R><E><E><I><E><R><E><V><N><I><L><R><E><I><R><H><P><N><I><I><T><L><H><D><I><F><E><N><K><T><D><V><V><L><I><L><E><L><V><S><G><G><E><L><F><D><F><L><A><E...
Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Involved in the regulation of smooth muscle contraction. Regulates both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell deaths sig...
O43293
B1IGD9
RL6_CLOBK
50S ribosomal protein L6
Clostridium
<M><S><R><V><G><K><L><P><V><A><I><P><N><G><V><T><V><T><V><T><P><D><N><V><V><T><V><K><G><P><K><G><E><L><V><K><A><M><S><N><K><I><N><I><A><V><E><D><N><S><V><V><V><T><R><D><N><D><H><K><D><V><R><A><L><H><G><L><T><R><A><L><I><N><N><M><V><T><G><V><N><E><G><Y><V><K><T><L><E><L><V><G><V><G><Y><R><A><Q><L><Q><G><K><K><L><V><L><S...
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.<BOP>
B1IGD9
Q8ZSY7
PYRG_PYRAE
UTP--ammonia ligase
Pyrobaculum
<M><P><K><L><I><I><V><T><G><G><V><M><S><G><V><G><K><G><V><V><V><A><S><I><G><R><I><L><R><A><R><G><L><S><V><N><A><V><K><I><D><P><Y><I><N><V><D><A><G><T><M><N><P><Y><A><H><G><E><V><F><V><T><Y><D><G><G><E><T><D><L><D><L><G><H><Y><E><R><F><L><D><V><E><L><S><K><R><N><N><I><T><S><G><Q><I><Y><L><T><V><I><E><K><E><R><R><G><E><Y...
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.<BOP>
Q8ZSY7
Q32RT3
YCF4_STAPU
Photosystem I assembly protein Ycf4
Staurastrum
<M><D><T><K><S><E><F><L><W><I><E><K><V><V><G><S><R><R><F><S><N><V><F><W><A><L><V><V><L><L><G><A><L><G><F><I><L><V><G><L><S><S><Y><L><N><K><D><I><I><S><F><L><P><S><Q><S><I><T><F><T><P><Q><G><L><V><M><C><F><Y><G><I><G><G><F><F><L><S><L><Y><L><W><F><A><I><L><W><D><V><G><S><G><Y><N><E><F><D><R><C><E><G><V><I><S><I><F><R><W...
Seems to be required for the assembly of the photosystem I complex.<BOP>
Q32RT3
A5EX57
FOLD_DICNV
Methenyltetrahydrofolate cyclohydrolase
Dichelobacter
<M><S><A><E><I><I><N><G><K><E><I><A><A><E><I><R><R><E><I><K><Q><E><T><A><Q><F><I><A><A><T><G><V><R><P><G><L><A><V><I><L><V><G><N><D><P><A><S><E><V><Y><V><R><N><K><G><I><Q><A><E><E><V><G><F><L><S><Q><I><Y><R><L><P><A><Q><T><T><Q><A><E><L><L><A><K><I><V><A><L><N><N><D><P><Q><I><C><G><I><L><V><Q><L><P><L><P><A><H><L><N><A...
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.<BOP>
A5EX57
Q0A5M1
NFI_ALKEH
Deoxyribonuclease V
Alkalilimnicola
<M><G><V><S><I><R><A><L><H><P><W><A><V><D><A><A><E><G><R><R><L><Q><Q><T><L><R><E><Q><L><C><L><K><T><P><R><G><F><R><P><R><L><V><A><G><V><D><A><G><V><V><D><G><G><R><T><I><R><A><A><V><V><V><M><S><L><P><D><L><A><V><V><T><Q><S><V><A><R><A><P><A><I><M><P><Y><V><P><G><L><L><S><F><R><E><L><P><G><V><V><R><A><L><E><Q><L><D><V><T...
DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.<BOP>
Q0A5M1
Q7H6I5
RPOA_ELYCA
Plastid-encoded RNA polymerase subunit alpha
Elymus
<M><V><R><E><E><V><A><G><S><T><Q><T><L><Q><W><K><C><V><E><S><R><V><D><S><K><R><L><Y><Y><G><R><F><I><L><S><P><L><R><K><G><Q><A><D><T><V><G><I><A><L><R><R><A><L><L><G><E><I><E><G><T><C><I><T><R><A><K><F><G><S><V><P><H><E><Y><S><T><I><A><G><I><E><E><S><V><Q><E><I><L><L><N><L><K><E><I><V><L><R><S><N><L><Y><G><V><R><D><A><S...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
Q7H6I5
Q8BYW9
EOGT_MOUSE
Extracellular O-linked N-acetylglucosamine transferase
Mus
<M><L><M><L><L><V><F><G><V><L><L><H><E><V><P><L><S><G><Q><D><K><A><H><S><E><A><D><D><A><P><G><K><A><L><Y><D><Y><S><S><L><R><L><P><A><E><H><I><P><F><F><L><H><N><N><R><H><V><A><S><V><C><R><E><D><S><H><C><P><Y><K><K><H><L><E><N><L><N><Y><C><W><G><Y><E><K><S><C><A><P><E><F><R><F><G><S><P><V><C><S><Y><V><D><L><G><W><T><D><T...
Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded...
Q8BYW9
Q7VMX7
DNLJ_HAEDU
Polydeoxyribonucleotide synthase [NAD(+)]
Haemophilus
<M><P><L><F><S><Q><F><E><L><S><N><N><I><T><P><T><Q><L><E><A><L><R><D><Q><L><R><E><Y><E><Y><H><Y><H><V><L><N><N><P><L><V><P><D><A><E><Y><D><R><L><I><N><Q><L><K><N><I><E><Q><Q><Y><P><E><L><I><T><P><D><S><P><T><Q><R><V><G><A><K><P><L><A><G><F><A><Q><V><A><H><E><M><P><M><L><S><L><D><N><A><F><S><E><T><D><L><D><N><F><L><R><R...
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP>
Q7VMX7
Q5H9F3
BCORL_HUMAN
BCL-6 corepressor-like protein 1
Homo
<M><I><S><T><A><P><L><Y><S><G><V><H><N><W><T><S><S><D><R><I><R><M><C><G><I><N><E><E><R><R><A><P><L><S><D><E><E><S><T><T><G><D><C><Q><H><F><G><S><Q><E><F><C><V><S><S><S><F><S><K><V><E><L><T><A><V><G><S><G><S><N><A><R><G><A><D><P><D><G><S><A><T><E><K><L><G><H><K><S><E><D><K><P><D><D><P><Q><P><K><M><D><Y><A><G><N><V><A><E...
Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor.<BOP>
Q5H9F3
Q6Y239
HBB_PAGMA
Hemoglobin beta chain
Pagrus
<M><V><E><W><T><D><A><E><R><S><A><I><K><T><L><W><G><K><I><N><V><A><E><I><G><P><Q><A><L><T><R><L><M><I><V><Y><P><W><T><Q><R><H><F><S><S><F><G><N><I><S><T><N><A><A><I><L><G><N><E><K><V><A><E><H><G><R><T><V><M><G><G><L><D><R><A><V><Q><N><L><D><D><I><K><N><A><Y><T><L><L><S><Q><K><H><S><E><I><I><H><V><D><P><D><N><F><R><L><L...
Involved in oxygen transport from gills to the various peripheral tissues.<BOP>
Q6Y239
Q0SXB2
MUTL_SHIF8
DNA mismatch repair protein MutL
Shigella
<M><P><I><Q><V><L><P><P><Q><L><A><N><Q><I><A><A><G><E><V><V><E><R><P><A><S><V><V><K><E><L><V><E><N><S><L><D><A><G><A><T><R><I><D><I><D><I><E><R><G><G><A><K><L><I><R><I><R><D><N><G><C><G><I><K><K><D><E><L><A><L><A><L><A><R><H><A><T><S><K><I><A><S><L><D><D><L><E><A><I><I><S><L><G><F><R><G><E><A><L><A><S><I><S><S><V><S><R...
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part ...
Q0SXB2
B9K8V0
APT_THENN
Adenine phosphoribosyltransferase
Thermotoga
<M><D><L><K><Q><F><I><R><D><I><P><D><F><P><Q><K><G><I><I><F><R><D><I><T><P><L><L><K><D><S><R><A><F><R><E><A><I><D><R><M><C><D><L><V><S><D><R><D><F><D><L><V><V><A><P><E><A><R><G><F><I><L><G><A><A><M><A><Y><K><L><G><K><G><F><V><P><V><R><K><P><G><K><L><P><Y><R><T><V><Y><E><E><Y><Q><L><E><Y><G><T><E><Q><L><H><I><H><E><D><A...
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.<BOP>
B9K8V0
P33906
DEAD_KLEPN
Cold-shock DEAD box protein A
Klebsiella
<M><A><E><F><E><T><T><F><A><D><L><G><L><K><A><P><I><L><E><A><L><T><D><L><G><Y><E><K><P><S><P><I><Q><A><E><C><I><P><H><L><L><D><G><R><D><V><L><G><M><A><Q><T><G><S><G><K><T><A><A><F><S><L><P><L><L><N><N><I><D><P><E><L><R><A><P><Q><I><L><V><L><A><P><T><R><E><L><A><V><Q><V><A><E><A><M><T><E><F><S><K><H><M><R><G><V><N><V><V...
DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.<BOP>
P33906
Q5E3D2
TGT_ALIF1
tRNA-guanine transglycosylase
Aliivibrio
<M><K><Y><E><L><I><K><K><Q><G><R><A><R><R><G><Q><L><Q><F><D><R><G><T><V><E><T><P><A><F><M><P><V><G><T><Y><G><T><V><K><G><M><T><P><E><E><V><K><G><T><G><A><E><I><L><L><G><N><T><F><H><L><W><L><R><P><G><Q><E><I><M><K><L><H><G><D><L><H><D><F><M><N><W><K><G><P><I><L><T><D><S><G><G><F><Q><V><F><S><L><G><K><T><R><K><I><T><E><E...
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th...
Q5E3D2
P83704
APOA2_HORSE
Apolipoprotein A2
Equus
<Q><A><E><E><S><C><L><Q><N><L><A><S><R><Y><L><Q><T><V><T><D><Y><G><K><D><L><V><E><K><A><L><A><P><E><L><Q><A><Q><A><K><A><Y><F><E><K><T><Q><E><Q><L><T><P><L><V><K><K><I><G><N><D><L><L><N><F><F><S><H><F><I><E><L><K><T><Q><P><A><T>
May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.<BOP>
P83704
Q28DX1
ERLN1_XENTR
Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1
Silurana
<M><A><H><F><G><V><V><V><G><L><M><M><I><L><V><F><L><V><F><L><S><S><I><H><K><V><E><E><G><H><L><A><V><Y><Y><R><G><G><A><L><L><G><G><P><G><D><P><G><Y><H><I><M><F><P><F><I><T><Y><F><R><S><V><Q><T><T><L><Q><T><D><E><V><K><N><V><P><C><G><T><S><G><G><V><M><I><Y><F><D><R><I><E><V><V><N><M><L><T><P><S><A><V><Y><D><V><V><R><N><Y...
Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex.<BOP>
Q28DX1
Q8DVF2
TRPA_STRMU
Tryptophan synthase alpha chain
Streptococcus
<M><T><K><T><L><T><K><H><L><Q><A><I><K><A><E><G><K><G><L><F><I><P><Y><I><M><A><G><D><H><D><K><G><L><D><G><L><F><D><T><I><S><F><L><E><A><Q><G><V><S><A><I><E><I><G><I><P><W><S><D><P><V><A><D><G><P><V><I><E><L><A><G><Q><R><S><L><V><K><G><T><S><L><A><S><I><I><A><R><L><Q><E><K><K><T><Q><V><P><L><V><I><M><T><Y><F><N><P><V><F...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
Q8DVF2
Q65HH2
AROQ_BACLD
Type II DHQase
Bacillus
<M><P><H><I><L><I><L><N><G><P><N><L><N><R><L><G><K><R><E><P><D><V><Y><G><T><D><T><L><T><D><L><E><Q><R><L><F><Q><F><A><E><G><I><Q><T><E><L><T><F><F><Q><S><N><H><E><G><D><L><I><D><A><L><H><E><A><E><E><Q><Y><D><G><I><V><L><N><P><G><A><F><S><H><Y><S><Y><A><L><R><D><A><V><A><A><I><S><I><P><V><I><E><V><H><L><S><N><P><H><A><R...
Catalyzes a trans-dehydration via an enolate intermediate.<BOP>
Q65HH2
Q92530
PSMF1_HUMAN
Proteasome inhibitor PI31 subunit
Homo
<M><A><G><L><E><V><L><F><A><S><A><A><P><A><I><T><C><R><Q><D><A><L><V><C><F><L><H><W><E><V><V><T><H><G><Y><F><G><L><G><V><G><D><Q><P><G><P><N><D><K><K><S><E><L><L><P><A><G><W><N><N><N><K><D><L><Y><V><L><R><Y><E><Y><K><D><G><S><R><K><L><L><V><K><A><I><T><V><E><S><S><M><I><L><N><V><L><E><Y><G><S><Q><Q><V><A><D><L><T><L><N...
Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.<BOP>
Q92530
Q10176
OST1_SCHPO
Oligosaccharyl transferase subunit alpha
Schizosaccharomyces
<M><L><V><L><K><L><L><L><W><S><I><I><S><G><L><S><L><A><E><Q><V><W><R><N><S><N><A><I><R><T><I><D><L><R><S><T><Y><T><K><T><L><T><S><L><I><I><V><N><E><G><D><E><P><Q><N><T><Y><R><Y><F><Q><Q><T><S><P><G><E><S><V><L><S><L><S><V><S><I><K><E><E><E><K><K><G><T><N><P><I><K><V><N><N><N><V><Y><D><I><P><L><Q><P><P><V><K><P><G><E><S...
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-...
Q10176
A5UAX1
NQRA_HAEIE
NQR-1 subunit A
Haemophilus
<M><I><T><I><K><K><G><L><D><L><P><I><A><G><K><P><A><Q><V><I><H><S><G><N><A><V><N><Q><V><A><I><L><G><E><E><Y><V><G><M><R><P><S><M><K><V><R><E><G><D><V><V><K><K><G><Q><V><L><F><E><D><K><K><N><P><G><V><I><F><T><A><P><A><S><G><T><I><T><A><I><N><R><G><E><K><R><V><L><Q><S><V><V><I><N><V><E><G><D><E><K><I><T><F><A><K><Y><S><T...
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.<BOP>
A5UAX1
A4TDC0
NUOC_MYCGI
NDH-1 subunit C
Mycolicibacterium
<M><T><E><P><T><G><D><Q><T><P><E><I><I><G><V><R><R><G><M><F><G><A><K><G><S><G><D><T><S><G><Y><G><R><L><V><R><P><V><A><L><P><G><G><S><P><R><P><Y><G><G><Y><F><D><E><V><V><D><R><L><A><E><A><V><G><D><D><A><F><T><E><S><I><E><R><V><V><I><H><R><D><E><L><T><L><E><V><H><R><D><R><L><V><E><V><A><Q><A><L><R><D><D><P><A><L><R><F><E...
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions ar...
A4TDC0
Q9SVF3
HPP5_ARATH
PAQR family protein HHP5
Arabidopsis
<M><G><D><E><A><E><I><K><E><H><L><K><P><Q><A><S><S><E><T><I><D><K><K><H><N><V><K><G><K><R><L><W><Q><K><V><K><Y><Q><L><V><E><F><H><S><L><P><A><Y><L><R><D><N><E><Y><I><I><G><H><Y><R><S><E><W><P><I><K><Q><I><L><L><S><I><F><T><I><H><N><E><T><L><N><V><W><T><H><L><I><G><F><F><L><F><L><A><L><T><I><Y><T><A><T><K><V><P><S><V><V...
May play a role in abiotic stress response.<BOP>
Q9SVF3
A1RQF1
RNPA_SHESW
Protein C5
Shewanella
<M><T><S><Y><T><F><T><R><E><L><R><L><L><T><P><A><Q><F><K><S><V><F><S><N><P><I><K><A><S><S><A><E><I><T><L><L><A><I><P><N><S><E><Q><H><P><R><L><G><L><T><V><A><K><R><Y><V><K><R><A><N><Q><R><N><R><I><K><R><I><I><R><D><S><F><R><L><N><Q><H><D><I><P><H><L><D><I><V><V><L><V><R><N><G><V><M><E><M><E><N><A><E><I><N><K><L><I><E><K...
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the riboz...
A1RQF1
Q8LG77
IDH6_ARATH
NAD(+)-specific ICDH 6
Arabidopsis
<M><T><M><T><A><F><L><A><R><R><L><I><G><N><G><S><S><Q><I><L><G><T><S><S><S><S><S><G><P><F><I><S><V><S><R><A><F><F><S><S><S><T><P><I><K><A><T><L><F><P><G><D><G><I><G><P><E><I><A><E><S><V><K><Q><V><F><T><A><A><D><V><V><I><D><W><D><E><Q><F><V><G><T><E><V><D><P><R><T><N><S><F><L><T><W><D><N><L><Q><S><V><L><K><N><K><V><G><L...
Catalytic subunit of the NAD(+)-dependent isocitrate dehydrogenase involved in the oxidative decarboxylation of isocitrate to 2-oxoglutarate (Probable). Performs an essential role in the oxidative function of the citric acid cycle.<BOP>
Q8LG77
C5JUE6
GATB_BLAGS
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial
Blastomyces
<M><I><R><Q><C><L><S><R><R><G><A><Y><S><R><Y><R><L><A><A><R><G><V><E><L><A><E><P><F><H><H><Q><S><S><R><P><Q><G><R><R><N><W><S><S><S><P><R><C><S><L><D><I><R><T><D><T><P><R><S><R><S><E><Y><V><P><L><R><K><Q><L><K><E><E><A><K><A><K><R><A><A><K><R><K><G><S><A><P><P><A><K><H><D><D><W><E><L><T><V><G><I><E><I><H><A><Q><L><D><T...
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).<BOP>
C5JUE6
C0MFB1
PNP_STRS7
Polynucleotide phosphorylase
Streptococcus
<M><S><K><Q><T><F><T><T><T><F><A><G><K><P><L><V><V><E><V><G><Q><V><A><K><Q><A><N><G><A><T><V><V><R><Y><G><E><S><T><V><L><T><A><A><V><M><S><K><K><M><S><T><G><D><F><F><P><L><Q><V><N><Y><E><E><K><M><Y><A><A><G><K><F><P><G><G><W><M><K><R><E><G><R><P><S><T><D><A><T><L><T><A><R><L><I><D><R><P><I><R><P><M><F><A><E><G><F><R><N...
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.<BOP>
C0MFB1
Q7ZUS4
ST2S2_DANRE
SULT1 ST2
Danio
<M><E><I><P><D><F><S><S><M><K><L><D><S><R><P><E><L><I><D><F><E><G><V><S><M><T><R><Y><F><T><D><N><W><E><K><V><K><N><F><Q><A><R><P><D><D><I><L><I><A><T><Y><P><K><A><G><T><T><W><V><S><Y><I><L><D><L><L><Y><F><G><N><E><S><P><E><R><Q><T><S><Q><P><I><Y><M><R><V><P><F><L><E><M><C><F><Q><G><L><P><L><G><T><E><L><A><D><T><L><P><T...
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L-thyronine), T4 (thyroxine), estrone and DOPA.<BOP>
Q7ZUS4
C6E5B9
LPXD_GEOSM
UDP-3-O-acylglucosamine N-acyltransferase
unclassified Geobacter
<M><K><K><T><L><R><E><I><A><E><Y><L><G><G><T><V><S><G><D><G><E><V><L><I><G><G><L><A><T><L><D><D><A><G><E><G><T><L><T><F><L><A><N><P><K><Y><A><A><K><V><A><T><T><K><A><S><A><V><L><M><G><T><G><G><N><T><H><G><K><N><A><I><F><H><P><N><P><Y><L><A><F><A><K><L><L><T><L><F><Y><T><A><P><A><K><P><V><G><V><L><P><G><A><F><V><A><D><G...
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.<BOP>
C6E5B9
B4S8W3
DDL_PROA2
D-alanylalanine synthetase
Prosthecochloris
<M><P><T><H><R><V><A><L><I><F><G><G><Q><S><T><E><H><E><I><S><I><I><S><A><R><A><I><A><N><H><I><D><T><E><A><Y><E><L><Y><P><I><Y><V><G><H><D><G><A><W><F><K><G><E><T><A><Q><K><V><L><D><L><D><M><P><A><M><L><A><N><T><S><A><D><T><I><R><E><R><L><R><E><I><S><F><S><D><P><R><N><R><F><L><F><D><F><S><E><E><G><I><D><V><A><L><P><I><I...
Cell wall formation.<BOP>
B4S8W3
Q00646
CDK1_EMENI
Never in mitosis protein X
Aspergillus subgen. Nidulantes
<M><E><N><Y><Q><K><I><E><K><I><G><E><G><T><Y><G><V><V><Y><K><A><R><E><L><T><H><P><N><R><I><V><A><L><K><K><I><R><L><E><A><E><D><E><G><V><P><S><T><A><I><R><E><I><S><L><L><K><E><M><N><D><P><N><I><V><R><L><L><N><I><V><H><A><D><G><H><K><L><Y><L><V><F><E><F><L><D><L><D><L><K><K><Y><M><E><A><L><P><V><S><E><G><G><R><G><R><A><L...
Cyclin-dependent kinase that acts as a master regulator of the mitotic and meiotic cell cycles.<BOP>
Q00646
A9NHL6
CH60_ACHLI
Chaperonin-60
Acholeplasma
<M><S><K><E><I><R><Y><G><K><D><A><K><Q><S><L><L><K><G><V><D><L><L><A><N><T><V><K><I><T><L><G><P><K><G><R><N><V><V><L><D><K><G><Y><G><S><P><L><I><T><N><D><G><V><S><I><A><K><E><I><E><L><K><D><P><Y><E><N><M><G><A><K><L><L><Y><E><V><A><S><K><T><N><D><V><A><G><D><G><T><T><T><A><T><L><L><A><Q><S><I><I><H><K><G><F><K><A><V><D...
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.<BOP>
A9NHL6
Q864H5
MSHR_SAGIM
Melanocortin receptor 1
Saguinus
<M><P><M><Q><G><A><Q><R><K><L><L><G><S><L><N><S><T><P><T><A><T><S><N><L><G><L><A><A><N><H><T><G><A><P><C><L><E><V><S><I><P><D><G><L><F><L><S><L><G><L><V><S><L><V><E><N><V><L><V><V><A><A><I><A><K><N><R><N><L><H><S><S><M><Y><C><F><I><C><C><L><A><L><S><D><L><L><V><S><G><S><N><M><L><E><T><A><V><I><L><L><L><E><A><G><A><L><A...
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.<BOP>
Q864H5
Q9ZUV9
CHX7_ARATH
Protein CATION/H+ EXCHANGER 7
Arabidopsis
<M><D><P><F><N><A><S><W><W><T><N><M><A><W><H><G><Y><S><L><S><E><D><G><T><K><F><C><E><M><L><P><T><K><I><N><S><F><G><L><S><E><K><I><L><H><K><S><V><G><L><Y><F><W><E><Y><P><L><P><N><L><E><L><I><I><L><S><V><F><F><F><W><Q><F><F><E><I><L><F><K><M><S><N><I><P><I><P><K><M><P><S><M><M><L><G><C><V><V><I><N><L><F><S><Y><T><R><P><G...
May operate as a cation/H(+) antiporter.<BOP>
Q9ZUV9
A0T0I0
RK23_PHATC
50S ribosomal protein L23, chloroplastic
Phaeodactylum
<M><I><N><S><S><D><F><S><R><S><S><A><Q><I><I><K><Y><P><I><I><T><D><K><A><T><R><L><L><E><N><N><Q><Y><S><F><V><V><D><R><Y><S><N><K><I><T><I><K><S><A><I><E><Y><L><F><N><V><K><V><I><K><I><N><T><C><R><L><P><R><K><Q><K><R><V><G><K><Y><V><G><W><K><P><Q><Y><K><K><A><I><V><T><L><S><E><G><D><I><I><N><L><F><T><D><S>
Binds to 23S rRNA.<BOP>
A0T0I0
A1VIL9
GATC_POLNA
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Polaromonas
<M><A><L><T><F><K><D><I><E><R><V><A><N><L><A><R><L><E><L><R><P><D><E><T><E><H><T><L><S><Q><L><N><G><F><F><A><L><V><E><Q><M><Q><A><V><N><T><D><G><V><E><P><L><A><H><P><A><A><L><L><G><E><V><A><L><R><L><R><E><D><I><A><S><E><P><N><Q><R><E><A><S><Q><A><S><A><P><A><V><E><R><G><L><F><L><V><P><K><V><I><E>
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated ...
A1VIL9
O87719
CHED_CAUVC
Probable chemoreceptor glutamine deamidase CheD
Caulobacter
<M><T><S><F><H><H><D><D><P><E><R><A><V><K><V><H><V><T><Q><G><E><S><H><V><T><A><D><P><N><V><V><M><T><T><V><L><G><S><C><I><A><A><C><I><R><D><P><Q><S><G><V><G><G><M><N><H><F><L><L><P><D><S><G><D><G><R><R><D><G><D><A><V><R><Y><G><A><Y><A><M><E><V><L><I><N><D><L><L><K><R><G><A><R><R><E><R><L><E><A><K><I><F><G><G><A><K><L><F...
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.<BOP>
O87719
O62446
LMLN_CAEEL
Leishmanolysin-like peptidase
Caenorhabditis
<M><K><P><R><L><I><F><I><F><F><A><C><Y><F><L><N><F><L><P><F><S><N><Q><L><P><C><S><Y><Q><N><P><R><I><E><D><I><L><L><E><V><P><I><E><H><E><H><P><H><R><H><R><R><G><L><P><S><S><D><P><T><S><P><P><V><E><K><F><A><P><L><R><I><Q><L><H><Y><D><K><S><I><Q><N><L><T><A><E><V><Q><N><F><V><N><T><T><L><L><P><E><A><V><G><Y><W><E><N><A><L...
Essential for the coordination of mitotic progression, and also plays a role in cell migration.<BOP>
O62446
O24428
STAD_ELAGV
Acyl-[acyl-carrier-protein] desaturase
Elaeis
<M><A><S><M><V><A><F><R><P><E><A><F><L><C><F><S><P><P><K><T><T><R><S><T><R><S><P><R><I><S><M><A><S><T><V><G><P><S><T><K><V><E><I><P><K><K><P><F><M><P><P><R><E><V><H><V><Q><V><T><H><S><M><P><P><Q><K><I><E><I><F><K><S><L><E><D><W><A><E><N><N><I><L><V><H><L><K><P><V><E><K><C><W><Q><P><Q><D><F><L><P><D><P><S><S><E><G><F><H...
Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons 9 and 10 of the acyl chain.<BOP>
O24428