accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
O34153 | GLPK_ENTCA | Glycerokinase | Enterococcus | <M><A><E><K><N><Y><V><M><A><I><D><Q><G><T><T><S><S><R><A><I><I><F><D><R><N><G><K><K><I><G><S><S><Q><K><E><F><P><Q><Y><F><P><K><S><G><W><V><E><H><N><A><N><E><I><W><N><S><V><Q><S><V><I><A><G><A><F><I><E><S><G><I><R><P><E><A><I><A><G><I><G><I><T><N><Q><R><E><T><T><V><V><W><D><K><T><T><G><Q><P><I><A><N><A><I><V><W><Q><S><R... | Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.<BOP> | O34153 |
Q87SE5 | MTNN_VIBPA | S-adenosylhomocysteine nucleosidase | Vibrio | <M><K><V><G><I><I><G><A><M><E><Q><E><V><T><I><L><K><E><A><M><T><N><C><Q><T><V><N><K><A><G><C><T><F><F><S><G><Q><I><N><D><V><D><V><V><L><L><Q><S><G><I><G><K><V><A><A><A><V><G><T><T><I><L><L><D><E><Y><Q><P><D><V><V><I><N><T><G><S><A><G><G><F><D><S><S><L><N><L><G><D><V><V><I><S><T><E><V><R><H><H><D><A><D><V><T><A><F><G><Y... | Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethio... | Q87SE5 |
P16084 | BGLS_BUTFI | Gentiobiase | Butyrivibrio | <M><E><K><W><A><R><I><K><Y><T><P><N><L><P><L><G><E><N><G><E><R><V><T><A><S><Q><K><H><I><E><L><S><C><E><A><A><C><E><G><M><V><L><L><K><N><D><R><N><V><L><P><I><R><K><G><T><R><V><A><L><F><G><K><G><V><F><D><Y><V><K><G><G><G><G><S><G><D><V><T><V><P><Y><I><R><N><L><Y><E><G><L><S><Q><Y><T><S><D><I><S><I><Y><D><K><S><V><R><F><Y... | B.fibrisolvens beta-glucosidase hydrolyzes cellobiose to a limited extent, cellotriose to cellobiose and glucose, and cellotetraose and cellopentaose to predominantly glucose.<BOP> | P16084 |
B1KWK7 | IF2_CLOBM | Translation initiation factor IF-2 | Clostridium | <M><A><K><I><R><V><Y><E><L><A><K><E><L><N><I><S><S><K><E><L><I><T><L><L><E><E><E><F><S><V><E><V><K><N><H><M><S><A><I><E><D><E><D><A><N><L><I><K><E><L><L><S><G><K><E><K><S><E><K><T><K><E><E><D><D><E><I><E><T><T><A><K><N><P><I><K><E><S><M><N><N><K><K><S><N><K><R><D><D><K><N><E><K><V><N><T><E><N><A><E><D><M><G><I><I><T><M... | One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.<BOP> | B1KWK7 |
B3WER9 | RIMP_LACCB | Ribosome maturation factor RimP | Lacticaseibacillus | <M><S><T><Q><S><V><V><E><T><V><T><A><L><V><K><P><I><L><D><D><H><H><F><Y><L><T><D><V><E><F><V><K><E><G><G><G><W><Y><L><R><V><Y><I><D><K><T><G><G><I><T><L><D><E><C><V><M><V><S><E><A><L><S><E><K><L><D><A><M><D><P><D><P><I><P><Q><Q><Y><F><L><E><V><S><S><P><G><A><E><R><P><L><K><H><E><T><D><Y><E><Q><A><V><G><D><Y><I><H><V><S... | Required for maturation of 30S ribosomal subunits.<BOP> | B3WER9 |
Q2T6R3 | GLGB_BURTA | Glycogen branching enzyme | pseudomallei group | <M><T><G><I><G><A><R><T><A><W><R><N><A><V><G><R><R><P><R><N><A><R><R><V><S><R><I><A><Y><R><V><S><R><V><A><C><R><V><S><R><I><A><Y><R><V><S><R><I><A><Y><R><V><S><R><V><A><W><R><N><V><A><P><A><A><R><R><A><H><R><P><F><P><A><V><I><H><I><A><S><G><I><P><L><P><T><E><P><L><P><A><P><P><V><V><V><D><R><P><A><S><P><D><D><A><A><L><I... | Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.<BOP> | Q2T6R3 |
Q4L4W3 | MNHE1_STAHJ | Mnh complex subunit E1 | Staphylococcus | <M><A><I><Q><I><I><L><N><F><I><L><A><F><I><W><I><F><L><S><G><S><Y><T><L><N><N><L><L><L><G><F><I><L><G><L><G><F><V><Y><L><F><S><R><I><L><P><G><R><F><Y><F><I><K><I><Y><K><I><L><K><L><A><V><V><F><F><V><E><L><L><K><A><N><I><D><V><L><K><I><V><L><Q><P><K><L><K><N><E><P><G><F><F><V><Y><H><T><D><L><K><T><D><W><Q><I><V><L><L><S... | Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.<BOP> | Q4L4W3 |
Q9VMD0 | DAXX_DROME | Daxx-like protein | Sophophora | <M><S><A><S><V><I><C><V><D><L><S><S><E><S><D><E><E><S><P><A><K><R><R><R><L><E><D><P><L><R><L><L><T><P><S><G><R><Q><S><F><P><A><K><L><L><N><I><P><K><A><S><L><G><S><A><M><V><V><P><V><A><E><T><G><P><A><R><E><T><P><V><I><V><D><P><L><R><S><M><H><I><P><S><G><I><T><I><T><K><H><Q><K><N><V><L><A><T><N><G><N><M><N><L><S><L><A><E... | Transcription regulator . Acts as a histone chaperone that facilitates deposition of histone H3.3 . Has a role in chromatin remodeling together with asf1 and XNP . Has role in the transcriptional apoptotic response to oxidative and UV stress .<BOP> | Q9VMD0 |
Q5HM03 | RS19_STAEQ | 30S ribosomal protein S19 | Staphylococcus | <M><A><R><S><I><K><K><G><P><F><V><D><D><H><L><M><K><K><V><E><A><Q><D><G><S><E><K><K><Q><V><I><K><T><W><S><R><R><S><T><I><F><P><N><F><I><G><H><T><F><A><V><Y><D><G><R><K><H><V><P><V><Y><V><T><E><D><M><V><G><H><K><L><G><E><F><A><P><T><R><T><F><K><G><H><A><A><D><D><K><K><T><R><R> | Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.<BOP> | Q5HM03 |
P34385 | MCCB_CAEEL | 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta | Caenorhabditis | <M><F><R><H><V><A><Q><N><L><G><S><R><N><T><S><I><Q><S><Y><R><L><L><R><T><R><W><E><R><G><Y><L><K><D><L><Y><H><R><R><Q><I><L><G><A><D><P><A><I><S><R><S><S><Y><P><N><C><S><V><Q><V><R><N><H><H><C><S><A><D><K><S><T><L><Q><W><A><P><I><K><T><S><I><D><N><S><S><D><D><F><A><A><N><T><A><E><M><K><V><L><V><E><D><L><K><A><K><I><S><K... | Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.<BOP> | P34385 |
Q1BEI3 | Y580_MYCSS | Putative S-adenosyl-L-methionine-dependent methyltransferase Mmcs_0580 | unclassified Mycobacterium | <M><S><A><L><A><V><A><L><A><R><Q><S><E><S><H><A><D><C><P><L><F><N><D><P><Y><A><Q><V><F><I><D><A><A><L><S><R><G><C><Q><L><P><S><D><E><T><S><E><R><I><N><G><I><A><N><Y><A><S><S><R><T><K><W><F><D><E><Y><F><I><A><A><G><A><H><G><L><E><Q><M><V><I><V><A><A><G><L><D><A><R><A><W><R><L><P><W><V><A><G><T><T><L><F><E><I><D><H><P><G... | Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.<BOP> | Q1BEI3 |
A0KJE0 | LFTR_AERHH | Phenyalanyltransferase | Aeromonas | <M><S><R><Y><L><T><Q><L><D><D><E><L><C><W><F><P><D><P><E><H><A><L><E><E><P><N><G><L><L><A><I><G><G><D><L><S><P><A><R><L><L><A><A><Y><H><K><G><I><F><P><W><N><E><P><H><Q><P><L><L><W><W><S><P><D><P><R><G><V><I><R><P><E><Q><L><H><I><G><R><T><L><R><K><F><I><R><G><T><S><F><D><I><S><I><D><R><A><F><N><E><V><I><A><A><C><A><A><P... | Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.<BOP> | A0KJE0 |
Q31RR2 | PSBH_SYNE7 | Photosystem II reaction center protein H | Synechococcus | <M><A><Q><R><T><R><L><G><D><I><L><R><P><L><N><S><E><Y><G><K><V><A><P><G><W><G><T><T><P><V><M><G><V><F><M><L><L><F><F><V><F><L><L><I><I><L><Q><I><Y><N><S><S><L><V><L><D><T><F><K><V><D><W><R><S><L><G><L> | One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a c... | Q31RR2 |
G8GJ95 | CLDS3_SALSC | Diterpene synthase Sa3 | Salvia incertae sedis | <M><T><S><V><N><L><S><R><A><P><A><A><I><T><R><R><R><L><Q><L><Q><P><E><F><H><A><E><C><S><W><L><K><S><S><S><K><H><A><P><L><T><L><S><C><Q><I><R><P><K><Q><L><S><Q><I><A><E><L><R><V><T><S><L><D><A><S><Q><A><S><E><K><D><I><S><L><V><Q><T><P><H><K><V><E><V><N><E><K><I><E><E><S><I><E><Y><V><Q><N><L><L><M><T><S><G><D><G><R><I><S... | Involved in the biosynthesis of labdane-type diterpenoid including sclareol, a diterpene-diol that is used as fragrance and flavoring, and has anticancer effects (able to kill leukemic and colon cancer cells by apoptosis) (Probable). Sclareol can also be used as synthesis precursor of ambergris substitution fragance pr... | G8GJ95 |
Q8DE95 | THIQ_VIBVU | Thiamine import ATP-binding protein ThiQ | Vibrio | <M><L><T><L><Q><Q><V><H><Y><Y><Y><H><Q><D><L><F><A><F><D><L><E><V><E><A><G><S><I><V><A><L><M><G><P><S><G><A><G><K><S><T><L><L><A><L><L><A><G><F><I><A><P><Q><S><G><Q><M><A><L><D><G><R><L><L><N><T><L><S><P><A><Q><R><P><F><S><M><L><F><Q><E><H><N><L><F><A><H><L><T><V><R><D><N><I><A><L><G><L><H><P><G><L><K><L><T><S><Q><Q><Q... | Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system.<BOP> | Q8DE95 |
Q94A32 | FAX2_ARATH | Protein FATTY ACID EXPORT 2, chloroplastic | Arabidopsis | <M><A><D><L><I><L><S><S><S><S><A><Q><S><S><L><L><H><V><R><P><N><H><Y><L><L><N><T><S><T><A><S><P><I><R><S><V><R><F><Q><N><S><N><G><F><H><P><L><A><F><A><S><G><H><R><R><L><P><L><G><A><V><V><P><S><D><S><T><K><T><I><T><S><T><I><T><A><N><C><V><D><S><G><V><K><A><V><E><V><E><P><T><I><D><Y><G><G><G><G><G><I><G><G><D><K><F><G><G... | May be involved in free fatty acids export from the plastids.<BOP> | Q94A32 |
Q5R9M9 | S39A6_PONAB | Zrt- and Irt-like protein 6 | Pongo | <M><A><R><K><L><S><V><I><L><I><L><T><F><A><L><S><V><T><N><P><L><H><E><L><K><A><A><A><F><P><Q><T><T><E><K><I><S><P><N><W><E><S><G><I><N><V><D><L><A><I><T><T><R><Q><Y><H><L><Q><Q><L><F><Y><R><Y><G><E><N><N><S><L><S><V><E><G><F><R><K><L><L><Q><N><I><G><I><D><K><I><K><R><I><H><I><H><H><D><H><E><H><H><S><D><H><E><H><H><S><D... | May act as a zinc-influx transporter.<BOP> | Q5R9M9 |
D2S4K7 | MSHA_GEOOG | N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase | Geodermatophilus | <M><A><A><R><R><R><P><R><S><A><V><P><R><R><V><A><T><L><S><V><H><T><S><P><L><D><Q><P><G><A><G><D><A><G><G><M><N><V><Y><V><V><E><V><S><R><R><L><A><E><R><G><I><A><V><D><V><F><T><R><A><V><S><S><D><L><P><P><V><V><E><M><S><P><G><V><T><V><R><H><V><S><A><G><P><F><E><G><L><G><K><E><E><L><P><A><Q><L><C><A><F><T><A><A><V><L><R><E... | Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.<BOP> | D2S4K7 |
Q7U3D7 | PPK1_PARMW | Polyphosphoric acid kinase | Parasynechococcus marenigrum | <M><S><S><A><V><L><S><P><D><R><Y><I><N><R><E><L><S><W><I><A><F><N><Q><R><V><L><A><Q><A><L><D><Q><R><T><P><L><L><D><Q><A><K><F><S><A><I><F><S><N><N><L><D><E><F><F><M><V><R><V><A><S><L><K><S><Q><V><E><A><G><I><T><T><P><S><E><D><G><K><T><P><L><E><Q><L><L><T><I><R><E><R><L><I><P><L><L><Q><Q><Q><Q><D><H><Y><R><K><Q><L><R><K... | Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).<BOP> | Q7U3D7 |
Q2G8S8 | TRPA_NOVAD | Tryptophan synthase alpha chain | Novosphingobium | <M><T><R><L><S><N><A><F><A><K><G><R><P><A><L><V><T><F><V><T><G><G><D><P><T><P><G><A><T><D><A><I><L><D><A><L><V><E><G><G><A><D><V><I><E><L><G><M><P><F><T><D><P><M><A><D><G><P><A><I><Q><L><A><N><L><R><S><L><G><A><G><T><K><T><A><D><V><F><R><I><A><A><D><F><R><A><R><H><P><E><V><P><L><V><L><M><G><Y><A><N><P><M><V><T><R><G><P... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | Q2G8S8 |
A7TEU3 | RSSA1_VANPO | 40S ribosomal protein S0-A | Vanderwaltozyma | <M><S><L><P><A><T><F><D><L><T><P><E><D><A><Q><L><L><L><A><A><N><T><H><L><G><A><R><N><V><Q><V><H><Q><E><P><Y><V><F><N><T><R><P><D><G><V><N><V><I><N><V><G><K><T><W><E><K><I><V><L><A><A><R><I><I><A><A><I><P><N><P><E><D><V><C><A><I><S><S><R><T><Y><G><Q><R><A><V><L><K><F><S><A><H><T><G><A><T><P><I><A><G><R><F><T><P><G><S><F... | Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.<BOP> | A7TEU3 |
E0VI98 | RU1C_PEDHC | U1 small nuclear ribonucleoprotein C | Pediculus | <M><P><K><Y><Y><C><D><Y><C><D><T><Y><L><T><H><D><S><P><S><V><R><K><T><H><C><Q><G><R><K><H><K><D><N><V><K><F><Y><Y><Q><K><W><M><E><E><Q><A><Q><H><L><I><D><A><T><T><A><A><F><K><A><G><K><I><A><N><P><F><A><P><K><P><G><A><A><I><P><P><P><A><N><M><Q><G><P><P><R><P><V><P><P><G><P><M><G><P><G><P><N><M><L><G><P><G><P><M><G><P><M... | Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seem... | E0VI98 |
B2V5U1 | DNLJ_SULSY | Polydeoxyribonucleotide synthase [NAD(+)] | unclassified Sulfurihydrogenibium | <M><Y><T><D><E><R><Q><K><E><L><I><K><L><T><Y><E><F><L><K><L><D><A><K><K><L><T><K><E><E><A><K><K><I><V><E><D><L><R><E><V><I><R><F><H><D><W><R><Y><Y><V><L><A><Q><P><V><I><S><D><Y><E><Y><D><K><L><F><K><L><L><K><D><I><E><G><K><Y><P><E><L><I><T><P><D><S><P><T><Q><R><V><P><S><E><I><T><K><V><F><P><Q><V><K><H><L><T><P><M><L><S... | DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.<BOP> | B2V5U1 |
P9WNK4 | ESXB_MYCTO | Secreted antigenic protein MTSA-10 | Mycobacterium tuberculosis complex | <M><A><E><M><K><T><D><A><A><T><L><A><Q><E><A><G><N><F><E><R><I><S><G><D><L><K><T><Q><I><D><Q><V><E><S><T><A><G><S><L><Q><G><Q><W><R><G><A><A><G><T><A><A><Q><A><A><V><V><R><F><Q><E><A><A><N><K><Q><K><Q><E><L><D><E><I><S><T><N><I><R><Q><A><G><V><Q><Y><S><R><A><D><E><E><Q><Q><Q><A><L><S><S><Q><M><G><F> | A secreted protein. Acts as a strong host T-cell antigen. Involved in translocation of bacteria from the host (human) phagolysosome to the host cytoplasm. Might serve as a chaperone to prevent uncontrolled membrane lysis by its partner EsxA.<BOP> | P9WNK4 |
A7NAA1 | UBIE_FRATF | Demethylmenaquinone methyltransferase | Francisella | <M><S><K><E><N><K><T><T><D><F><G><F><T><Q><V><P><W><E><E><K><Q><K><K><V><A><G><V><F><H><S><V><A><A><K><Y><D><L><M><N><D><L><M><S><F><G><I><H><R><I><W><K><K><Q><T><I><A><K><S><G><V><R><K><G><D><N><V><L><D><L><A><G><G><T><G><D><L><A><Y><K><F><C><Q><M><V><G><Q><Q><G><K><V><I><L><S><D><I><N><S><S><M><L><E><V><G><K><E><K><L... | Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).<BOP> | A7NAA1 |
Q3TC72 | FAHD2_MOUSE | Fumarylacetoacetate hydrolase domain-containing protein 2A | Mus | <M><L><G><F><G><R><R><R><L><F><S><A><L><L><Q><V><Q><K><R><P><C><Q><P><S><R><N><M><R><L><V><Q><F><Q><A><P><H><L><E><E><P><H><L><G><L><E><S><G><V><G><G><G><V><V><D><L><N><A><F><D><S><T><L><P><K><T><M><V><Q><F><L><E><Q><G><E><T><T><L><S><V><A><R><R><A><L><A><T><Q><L><P><V><I><P><R><S><Q><V><T><F><L><A><P><V><T><R><P><E><K... | May have hydrolase activity.<BOP> | Q3TC72 |
A5F5R5 | UNG_VIBC3 | Uracil-DNA glycosylase | Vibrio | <M><S><E><S><L><T><W><H><D><V><I><G><N><E><K><Q><Q><A><Y><F><Q><Q><T><L><Q><F><V><E><S><Q><R><Q><A><G><K><V><I><Y><P><P><A><K><D><V><F><N><A><F><R><F><T><E><F><G><D><V><K><V><V><I><L><G><Q><D><P><Y><H><G><P><N><Q><A><H><G><L><C><F><S><V><L><P><G><V><K><T><P><P><S><L><V><N><I><Y><K><E><L><A><Q><D><I><P><G><F><Q><I><P><P... | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.<BOP> | A5F5R5 |
Q4PSK3 | FLZ16_ARATH | FCS-Like Zinc finger 16 | Arabidopsis | <M><A><N><I><M><I><P><S><K><R><P><R><A><P><S><F><S><E><K><H><P><K><Y><V><G><S><S><D><W><L><P><A><E><K><D><K><A><Q><V><Q><L><T><N><F><L><E><L><C><R><F><C><K><K><N><L><R><H><D><E><D><V><F><M><Y><G><Y><L><G><A><F><C><S><K><Q><C><R><A><K><Q><M><A><C><D><V><F><R><D><F><S><R><Q><K><A><N><V><K><K><G><R><T><S><K><D><E><G><L><D... | May act as an adapter to facilitate the interaction of SnRK1 complex with effector proteins, conferring tissue- and stimulus-type specific differences in the SnRK1 regulation pathway.<BOP> | Q4PSK3 |
A0A067Z9B6 | FMAD_ASPFU | Fumagillin biosynthesis methyltransferase | Aspergillus subgen. Fumigati | <M><A><D><I><A><E><Q><L><I><E><K><L><Q><T><L><E><T><S><I><F><E><G><Q><D><A><T><R><Q><K><L><A><L><A><A><R><K><L><F><H><T><L><E><T><K><E><E><K><T><M><R><L><A><I><E><E><P><V><M><F><S><V><L><Q><A><L><I><D><T><G><L><F><E><G><W><A><A><A><G><G><G><E><R><D><V><T><E><L><A><K><L><S><K><R><D><V><E><P><E><L><L><R><H><Q><L><R><L><M... | O-methyltransferase; part of the gene cluster that mediates the biosynthesis of fumagillin, a meroterpenoid that has numerous biological activities including irreversible inhibition of human type 2 methionine aminopeptidase (METAP2) . The pathway begins with the conversion of farnesyl pyrophosphate (FPP) to beta-trans-... | A0A067Z9B6 |
Q7NJF8 | PSBX_GLOVI | Photosystem II reaction center X protein | Gloeobacter | <M><T><A><T><L><S><N><F><L><W><S><I><F><W><G><G><V><V><V><A><L><G><A><A><A><L><T><A><I><S><R><I><D><R><I><R> | Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.<BOP> | Q7NJF8 |
Q9SGU9 | MGL_ARATH | L-methioninase | Arabidopsis | <M><A><H><F><L><E><T><Q><E><P><L><V><F><S><G><K><K><R><N><D><R><D><D><E><D><G><D><A><L><V><A><K><K><S><A><L><A><V><C><D><A><D><P><A><A><A><I><A><N><I><R><H><E><F><G><E><H><G><G><V><N><M><S><I><E><A><S><A><T><F><T><V><M><E><P><D><T><M><R><R><M><F><T><G><E><L><G><P><D><N><D><F><Y><V><Y><S><R><H><F><N><P><T><V><L><N><L><S... | Catalyzes the degradation of L-methionine to alpha-ketobutyrate, methanethiol and ammonia. Exhibits a high activity toward L-methionine, L-ethionine, L-homocysteine and seleno-L-methionine, but not L-cysteine. Involved in an alternative cysteine biosynthesis pathway to the reverse trans-sulfuration pathway (methionine-... | Q9SGU9 |
Q8KA30 | PMBA_BUCAP | Metalloprotease PmbA homolog | Buchnera | <M><Q><L><L><N><Q><I><E><K><E><E><N><L><L><I><E><K><V><K><N><T><L><F><L><A><Q><E><K><V><N><C><S><I><E><V><C><V><K><K><T><I><G><I><S><V><N><I><R><N><S><I><V><E><N><V><E><F><N><N><D><S><I><L><F><V><T><V><Y><N><K><F><S><K><G><V><S><S><S><K><D><F><S><T><N><G><I><K><K><M><L><E><I><A><I><D><I><S><K><H><T><S><S><D><F><F><S><G... | Probable metalloprotease.<BOP> | Q8KA30 |
Q8DH03 | LGT_THEVB | Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase | Thermosynechococcus | <M><I><A><A><F><Q><S><P><G><A><T><L><E><L><G><F><I><T><L><R><W><Y><G><L><L><I><A><V><A><V><F><I><G><I><W><L><S><Q><R><L><A><R><Q><R><Q><I><D><P><E><Q><I><A><D><L><S><I><W><L><V><V><A><A><I><P><A><A><R><L><Y><Y><V><A><F><N><W><G><F><Y><Q><K><H><L><D><Q><V><V><Q><I><W><K><G><G><I><A><I><H><G><A><I><L><G><G><I><V><A><M><A... | Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.<BOP> | Q8DH03 |
P37974 | CNRC_CUPMC | Nickel and cobalt resistance protein CnrC | Cupriavidus | <M><K><Q><V><I><S><S><F><L><C><R><P><R><F><V><G><S><A><I><W><L><L><P><V><A><L><S><H><A><A><E><A><P><P><F><P><N><L><L><Q><Q><S><L><A><L><A><P><A><M><V><A><Q><A><A><N><V><R><A><A><G><A><D><A><A><Q><A><Q><A><W><L><N><P><R><I><D><T><V><L><E><N><L><G><A><P><S><S><D><G><L><S><Q><R><Q><N><T><Y><S><I><T><Q><P><F><E><L><G><G><K... | The products of the genes cnrA, cnrB, and cnrC are likely to form a membrane-bound protein complex catalyzing an energy-dependent efflux of Ni(2+) and Co(2+). The mechanism of action of the CnrCBA complex may be that of a proton/cation antiporter.<BOP> | P37974 |
P28794 | MBP1_MAIZE | Antimicrobial peptide MBP-1 | Zea | <R><S><G><R><G><E><C><R><R><Q><C><L><R><R><H><E><G><Q><P><W><E><T><Q><E><C><M><R><R><C><R><R><R><G> | Inhibitor of both bacterial and fungal growth in vitro.<BOP> | P28794 |
Q83Z42 | OPGH_XANEU | Glucans biosynthesis glucosyltransferase H | Xanthomonas | <M><D><G><T><V><T><P><S><P><T><T><T><A><M><P><P><V><S><A><L><D><A><G><T><P><T><L><P><P><E><A><P><L><A><M><P><E><Q><N><L><R><E><G><S><L><Q><V><R><H><Q><R><T><S><P><P><G><I><G><V><R><R><F><Y><L><I><G><G><T><F><A><T><T><A><I><A><V><W><V><M><L><S><V><L><W><P><D><G><I><S><V><L><E><G><C><L><L><G><L><F><V><L><L><F><A><W><I><A... | Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).<BOP> | Q83Z42 |
A1ALV4 | RS14Z_PELPD | 30S ribosomal protein S14 type Z | Pelobacter | <M><A><K><V><S><M><I><I><K><S><Q><R><K><P><K><F><K><V><Q><Q><H><N><R><C><E><V><C><G><R><P><K><A><F><Y><R><K><F><R><M><C><R><I><C><L><R><K><Y><A><S><I><G><Q><I><P><G><V><I><K><S><S><W> | Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.<BOP> | A1ALV4 |
B5EXG6 | THII_SALA4 | tRNA 4-thiouridine synthase | Salmonella | <M><K><F><I><I><K><L><F><P><E><I><T><I><K><S><Q><S><V><R><L><R><F><I><K><I><L><T><G><N><I><R><N><V><L><K><H><Y><D><E><T><L><A><V><V><R><H><W><D><N><I><E><V><R><A><K><D><E><N><Q><R><L><A><I><R><D><A><L><T><R><I><P><G><I><H><H><I><L><E><V><E><D><V><P><F><T><D><M><H><D><I><F><E><K><A><L><A><Q><Y><R><E><Q><L><E><G><K><T><F... | Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynt... | B5EXG6 |
Q13EM1 | RS15_RHOPS | 30S ribosomal protein S15 | Rhodopseudomonas | <M><S><I><T><A><E><R><K><A><E><V><I><Q><G><N><A><N><K><A><G><D><T><G><S><P><E><V><Q><V><A><I><L><S><E><R><I><V><N><L><T><A><H><F><K><T><H><T><K><D><N><H><S><R><R><G><L><L><K><L><V><S><T><R><R><S><L><L><D><Y><V><K><K><K><D><E><A><R><Y><K><A><L><L><E><K><H><N><I><R><R> | Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.<BOP> | Q13EM1 |
Q8DV10 | CAPP_STRMU | Phosphoenolpyruvate carboxylase | Streptococcus | <M><T><I><N><K><L><E><S><R><N><D><K><E><A><I><A><E><E><I><T><I><L><T><K><L><L><D><D><A><T><K><T><M><V><G><S><A><S><F><D><K><I><T><L><F><K><K><L><S><I><E><E><K><H><Q><E><L><E><R><E><I><E><Q><L><T><N><E><E><M><V><V><V><S><R><Y><F><S><I><L><P><L><L><I><N><I><S><E><D><V><N><L><A><Y><E><I><N><Y><Q><N><N><N><D><I><D><Y><L><G... | Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.<BOP> | Q8DV10 |
Q980A0 | APGM_SACS2 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase | Saccharolobus | <M><K><Q><Y><K><I><L><L><I><V><A><D><G><L><G><D><R><P><V><S><K><L><N><G><L><T><P><L><E><A><A><N><K><P><A><I><T><D><L><L><K><N><S><M><I><G><L><M><D><P><I><S><P><G><I><I><P><G><S><D><T><S><H><L><S><I><F><G><L><D><P><H><V><Y><Y><R><G><R><G><A><F><E><A><L><G><A><G><A><T><L><S><H><G><D><V><A><F><R><G><N><F><A><T><V><N><N><D... | Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.<BOP> | Q980A0 |
B4SQK2 | YBEY_STRM5 | Endoribonuclease YbeY | Stenotrophomonas maltophilia group | <M><T><R><G><P><V><R><L><D><V><A><I><S><Y><A><L><P><R><A><G><L><P><A><A><V><S><F><R><K><W><V><A><A><A><L><K><G><R><I><R><E><A><D><L><A><I><R><V><V><D><A><K><E><G><Q><S><L><N><R><H><Y><R><G><K><D><Y><A><T><N><V><L><S><F><P><A><D><V><P><E><G><L><P><K><G><V><K><F><P><L><L><G><D><L><V><I><C><A><P><V><V><A><R><E><A><D><E><Q... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | B4SQK2 |
Q8KX32 | TRPA_SYNP2 | Tryptophan synthase alpha chain | unclassified Synechococcus | <M><T><S><V><S><E><R><F><R><S><L><K><Q><A><G><Q><C><A><L><I><P><F><I><T><A><G><D><P><D><L><E><T><T><E><Q><A><L><K><I><L><D><A><A><G><A><D><F><I><E><L><G><V><P><Y><S><D><P><L><A><D><G><P><T><I><Q><A><A><A><T><R><A><L><S><R><G><V><T><L><E><Q><V><L><A><I><V><Q><R><V><H><G><Q><L><T><A><P><I><I><L><F><T><Y><Y><N><P><I><F><Y... | The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP> | Q8KX32 |
C6DHS9 | DCUP_PECCP | Uroporphyrinogen decarboxylase | Pectobacterium | <M><T><D><L><K><N><D><R><Y><L><R><A><L><L><R><Q><P><V><D><V><T><P><V><W><M><M><R><Q><A><G><R><Y><L><P><E><Y><K><A><T><R><A><Q><A><G><D><F><M><S><L><C><K><N><A><E><L><A><C><E><V><T><L><Q><P><L><R><R><Y><A><L><D><A><A><I><L><F><S><D><I><L><T><I><P><D><A><M><G><L><G><L><Y><F><E><A><G><E><G><P><R><F><H><S><P><I><T><S><H><A... | Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.<BOP> | C6DHS9 |
C5G6H8 | CYNS_AJEDR | Cyanate lyase | Blastomyces | <M><S><N><L><N><L><A><T><L><D><I><S><E><H><A><N><L><P><T><S><S><E><V><L><F><K><A><K><A><D><K><K><L><S><F><E><S><I><A><A><A><I><G><R><N><E><V><A><T><A><A><I><F><Y><G><Q><A><K><A><S><E><E><D><I><A><K><L><A><Q><V><L><E><I><D><H><A><H><L><E><S><L><L><S><G><F><P><D><R><G><K><S><V><S><F><P><P><K><D><P><L><I><Y><R><L><Y><E><I... | Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.<BOP> | C5G6H8 |
Q1MIW0 | SYDND_RHIL3 | Non-discriminating aspartyl-tRNA synthetase | Rhizobium | <M><H><R><Y><R><S><H><T><C><A><A><L><R><K><S><D><V><G><S><T><V><R><I><S><G><W><V><H><R><V><R><D><H><G><G><V><L><F><I><D><L><R><D><H><Y><G><I><T><Q><V><V><A><D><P><D><S><P><A><F><Q><M><A><E><T><V><R><G><E><W><V><I><R><I><D><G><L><V><K><A><R><T><E><D><T><V><N><K><T><M><A><T><G><E><I><E><L><Y><A><Q><E><I><E><V><L><S><A><A... | Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).<BOP> | Q1MIW0 |
A9NCN3 | MUTS_COXBR | DNA mismatch repair protein MutS | Coxiella | <M><E><L><Q><T><K><S><P><T><T><Q><N><D><F><S><Q><H><T><P><M><M><R><Q><Y><L><R><I><K><A><E><Y><P><D><L><L><V><F><Y><R><M><G><D><F><Y><E><L><F><Y><D><D><A><K><K><A><A><K><L><L><N><I><T><L><T><A><R><G><Q><S><A><G><H><A><I><P><M><A><G><V><P><Y><H><A><V><E><N><Y><L><T><K><L><V><R><L><G><E><S><V><V><I><C><E><Q><I><G><D><P><A... | This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.<BOP> | A9NCN3 |
Q8BY46 | ZN574_MOUSE | Zinc finger protein 574 | Mus | <M><T><E><E><S><E><E><T><V><L><Y><I><E><H><R><Y><V><C><S><E><C><N><Q><L><Y><G><S><L><E><E><V><L><V><H><Q><N><S><H><V><P><Q><Q><H><F><E><L><V><G><V><A><D><P><G><V><T><V><A><T><E><A><A><S><G><T><G><L><Y><Q><T><L><I><Q><E><S><Q><Y><Q><C><L><E><C><G><Q><L><L><L><S><P><S><Q><L><L><E><H><Q><E><L><H><L><K><M><M><A><P><Q><E><A... | May be involved in transcriptional regulation.<BOP> | Q8BY46 |
B2UTI4 | SYE2_HELPS | Glutamyl-tRNA synthetase 2 | Helicobacter | <M><L><R><F><A><P><S><P><T><G><D><M><H><I><G><N><L><R><A><A><I><F><N><Y><I><V><A><K><Q><Q><H><K><P><F><L><I><R><I><E><D><T><D><K><E><R><N><I><E><G><K><D><Q><E><I><L><E><I><L><K><L><M><G><I><S><W><D><K><L><V><Y><Q><S><R><N><I><D><Y><H><R><E><M><A><E><K><L><L><K><E><N><K><A><F><Y><C><Y><A><S><T><E><F><L><E><R><E><K><E><K... | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).<BOP> | B2UTI4 |
Q96L58 | B3GT6_HUMAN | UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 | Homo | <M><K><L><L><R><R><A><W><R><R><R><A><A><L><G><L><G><T><L><A><L><C><G><A><A><L><L><Y><L><A><R><C><A><A><E><P><G><D><P><R><A><M><S><G><R><S><P><P><P><P><A><P><A><R><A><A><A><F><L><A><V><L><V><A><S><A><P><R><A><A><E><R><R><S><V><I><R><S><T><W><L><A><R><R><G><A><P><G><D><V><W><A><R><F><A><V><G><T><A><G><L><G><A><E><E><R><R... | Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate. Has no activity towards substr... | Q96L58 |
Q9ZJM5 | DNAB_HELPJ | Replicative DNA helicase | Helicobacter | <M><D><H><L><K><H><L><Q><Q><L><Q><N><I><E><R><I><V><L><S><G><I><V><L><A><N><H><K><I><E><E><I><H><S><V><L><E><P><S><D><F><Y><Y><P><P><H><G><L><F><F><E><I><A><L><K><L><H><E><V><N><C><P><I><D><E><N><F><I><R><Q><K><M><P><K><D><K><Q><I><S><E><D><D><L><V><A><I><F><A><A><S><P><I><D><N><I><E><A><Y><V><E><E><I><K><N><A><S><I><K... | Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.<BOP> | Q9ZJM5 |
A2RI79 | RF3_LACLM | Peptide chain release factor 3 | Lactococcus cremoris subsp. cremoris | <M><T><L><Q><E><E><I><K><K><R><R><T><F><A><I><I><S><H><P><D><A><G><K><T><T><I><T><E><Q><L><L><K><F><G><G><A><I><R><E><A><G><T><V><K><A><R><K><T><G><N><F><A><K><S><D><W><M><D><I><E><K><E><R><G><I><S><V><T><S><S><V><M><Q><F><D><Y><A><G><K><R><V><N><I><L><D><T><P><G><H><E><D><F><S><E><D><T><Y><R><T><L><M><A><V><D><A><A><V... | Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.<BOP> | A2RI79 |
P28628 | LEPS_BACSU | Leader peptidase I | Bacillus | <M><K><S><E><N><V><S><K><K><K><S><I><L><E><W><A><K><A><I><V><I><A><V><V><L><A><L><L><I><R><N><F><I><F><A><P><Y><V><V><D><G><D><S><M><Y><P><T><L><H><N><R><E><R><V><F><V><N><M><T><V><K><Y><I><G><E><F><D><R><G><D><I><V><V><L><N><G><D><D><V><H><Y><V><K><R><I><I><G><L><P><G><D><T><V><E><M><K><N><D><Q><L><Y><I><N><G><K><K><V... | Not essential for cell viability, but required for efficient secretion of many proteins.<BOP> | P28628 |
Q0HLD7 | TORD_SHESM | Chaperone protein TorD | Shewanella | <M><S><N><V><D><I><N><H><A><R><A><L><V><Y><Q><L><L><S><S><L><F><A><R><E><I><D><E><Q><R><L><K><Q><L><T><S><E><Q><A><Q><Q><F><W><T><Q><L><G><Y><A><P><E><F><S><A><P><V><A><S><I><Q><K><V><L><N><D><L><T><S><D><E><A><L><L><E><L><A><A><D><Y><C><G><L><F><L><V><G><T><K><Y><S><A><S><P><Y><A><S><L><Y><L><S><P><E><E><E><P><L><L><F... | Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.<BOP> | Q0HLD7 |
Q2NIX1 | RS5_AYWBP | 30S ribosomal protein S5 | Candidatus Phytoplasma asteris | <M><S><Q><I><R><L><T><F><L><K><E><K><N><K><M><K><A><I><K><K><E><F><N><K><K><A><A><L><L><E><E><K><V><V><K><I><N><R><I><T><K><V><V><K><G><G><A><R><F><R><F><S><A><L><V><V><V><G><D><K><K><G><Q><I><G><F><A><T><A><K><A><K><E><I><V><E><A><I><K><K><A><L><E><K><A><K><K><Q><L><V><R><I><P><I><V><G><T><T><I><P><H><D><T><I><G><R><F... | Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<BOP> | Q2NIX1 |
A5CSL5 | MIAB_CLAM3 | tRNA-i(6)A37 methylthiotransferase | Clavibacter | <M><S><T><L><A><E><H><V><R><D><T><P><P><A><A><E><R><P><R><T><Y><E><V><R><T><Y><G><C><Q><M><N><V><H><D><S><E><R><L><T><G><S><L><E><A><A><G><Y><V><S><A><E><G><A><E><A><D><I><V><V><I><N><T><C><A><V><R><E><N><A><D><N><K><L><Y><G><N><L><G><H><L><A><G><V><K><R><R><H><E><G><M><Q><I><A><V><G><G><C><L><A><Q><K><D><R><A><T><V><L... | Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.<BOP> | A5CSL5 |
A2BTJ7 | RUVB_PROMS | Holliday junction ATP-dependent DNA helicase RuvB | Prochlorococcus | <M><A><I><I><S><S><N><I><G><D><N><D><F><S><F><R><K><K><E><L><R><L><V><D><S><K><N><I><P><E><E><K><R><N><N><N><L><N><L><A><R><P><L><N><L><K><E><F><I><G><Q><E><Q><L><K><S><S><L><R><V><A><I><D><A><S><I><I><R><K><E><P><L><E><H><T><L><L><Y><G><Q><P><G><L><G><K><T><T><L><A><F><L><I><A><H><E><L><N><T><K><C><R><I><A><T><A><P><A... | The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.<BOP> | A2BTJ7 |
P27624 | RECA_STRMU | Recombinase A | Streptococcus | <M><A><K><R><I><K><K><T><E><E><I><T><K><K><F><G><D><E><R><K><K><A><L><D><D><A><L><K><N><I><E><K><D><F><G><K><G><A><V><M><R><L><G><E><R><A><E><Q><K><V><Q><V><M><S><S><G><S><L><A><L><D><I><A><L><G><A><G><G><Y><P><K><G><R><I><V><E><I><Y><G><P><E><S><S><G><K><T><T><V><A><L><H><A><V><A><Q><A><Q><K><D><G><G><I><A><A><F><I><D... | Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.<BOP> | P27624 |
P20729 | CHHA3_BOMMO | Chorion class high-cysteine HCA protein 13 | Bombyx | <M><F><T><F><A><I><L><L><L><C><V><Q><G><C><L><I><Q> | This protein is one of many from the eggshell of the silk moth.<BOP> | P20729 |
A1ANE2 | CBIM2_PELPD | Energy-coupling factor transporter probable substrate-capture protein CbiM 2 | Pelobacter | <M><H><I><M><E><G><F><L><P><V><E><H><A><I><G><W><S><V><A><S><A><P><V><V><A><Y><G><L><Y><S><I><N><K><K><I><K><K><N><P><E><Q><R><M><L><L><G><V><A><A><A><F><T><F><V><L><S><A><L><K><M><P><S><V><T><G><S><C><S><H><P><T><G><T><G><L><G><A><I><L><F><G><P><S><A><V><A><P><I><G><A><V><V><L><L><F><Q><A><L><L><L><A><H><G><G><L><T><T... | Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.<BOP> | A1ANE2 |
B1AJH7 | TRUA_UREP2 | tRNA-uridine isomerase I | Ureaplasma | <M><N><Y><K><I><S><L><R><Y><D><G><S><L><F><Y><G><W><A><R><Q><P><Q><K><R><T><V><Q><G><D><L><E><E><I><F><K><S><I><F><K><I><N><N><I><R><I><I><G><S><G><R><T><D><K><G><V><H><A><Y><E><Q><T><F><S><V><K><H><S><A><L><K><Y><D><S><H><I><I><Y><Q><A><L><C><S><R><T><S><S><D><I><Q><I><L><E><V><Q><K><V><D><D><S><F><H><A><Q><Y><N><A><T... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | B1AJH7 |
A9VTA2 | RLMN_BACMK | tRNA m2A37 methyltransferase | Bacillus cereus group | <M><E><T><T><V><K><K><Q><K><K><N><L><E><T><K><K><P><S><I><Y><S><L><Q><L><H><E><M><Q><D><W><L><K><E><Q><G><E><P><K><F><R><A><G><Q><I><F><D><W><L><Y><K><K><R><V><K><N><Y><E><D><M><S><N><L><A><K><G><L><R><D><K><L><S><N><S><F><D><I><T><T><L><N><T><L><V><K><Q><T><S><S><D><G><T><I><K><F><L><F><Q><L><Y><D><G><Y><S><I><E><T><V... | Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.<BOP> | A9VTA2 |
Q39Q76 | PRMA_GEOMG | Ribosomal protein L11 methyltransferase | Geobacter | <M><D><K><T><W><A><E><V><T><C><E><I><P><A><A><M><I><D><L><L><A><D><F><L><V><E><L><S><G><N><G><V><S><I><D><N><L><E><L><D><T><F><S><L><D><T><M><D><E><A><P><V><K><T><V><R><A><Y><F><T><P><D><D><E><L><E><E><K><L><A><A><L><N><R><F><I><Q><E><H><A><P><A><Y><G><D><A><A><P><A><P><P><T><V><T><T><L><R><E><E><D><W><A><T><G><W><R><Q... | Methylates ribosomal protein L11.<BOP> | Q39Q76 |
P02649 | APOE_HUMAN | Apolipoprotein E | Homo | <M><K><V><L><W><A><A><L><L><V><T><F><L><A><G><C><Q><A><K><V><E><Q><A><V><E><T><E><P><E><P><E><L><R><Q><Q><T><E><W><Q><S><G><Q><R><W><E><L><A><L><G><R><F><W><D><Y><L><R><W><V><Q><T><L><S><E><Q><V><Q><E><E><L><L><S><S><Q><V><T><Q><E><L><R><A><L><M><D><E><T><M><K><E><L><K><A><Y><K><S><E><L><E><E><Q><L><T><P><V><A><E><E><T... | (Microbial infection) Through its interaction with HCV envelope glycoprotein E2, participates in the attachment of HCV to HSPGs and other receptors (LDLr, VLDLr, and SR-B1) on the cell surface and to the assembly, maturation and infectivity of HCV viral particles . This interaction is probably promoted via the up-regul... | P02649 |
Q24T29 | CSRA_DESHY | Translational regulator CsrA | Desulfitobacterium | <M><L><A><L><T><R><K><A><G><E><R><I><V><I><G><D><N><I><V><V><T><V><V><S><I><K><G><D><S><I><R><L><T><I><D><A><P><K><E><V><K><I><Y><R><G><E><I><Y><D><A><I><A><A><E><N><K><E><A><A><V><P><M><D><L><T><E><L><T><A><L><K><E><F><H><I><R><K> | A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by Fli... | Q24T29 |
P45575 | DSVB_DESVH | Hydrogensulfite reductase subunit beta | Desulfovibrio | <M><A><F><I><S><S><G><Y><N><P><E><K><P><M><A><N><R><I><T><D><I><G><P><R><K><F><D><E><F><F><P><P><V><I><A><K><N><F><G><S><W><L><Y><H><E><I><L><E><P><G><V><L><M><H><V><A><E><S><G><D><K><V><Y><T><V><R><V><G><A><A><R><L><M><S><I><T><H><I><R><E><M><C><D><I><A><D><K><Y><C><G><G><H><L><R><F><T><T><R><N><N><V><E><F><M><V><A><D... | Catalyzes the reduction of sulfite to sulfide. This is the terminal oxidation reaction in sulfate respiration, a process catalyzed by the sulfate-reducing bacteria.<BOP> | P45575 |
A5FIL6 | LIPB_FLAJ1 | Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase | Flavobacterium | <M><N><K><K><I><Q><L><Q><D><L><G><N><R><D><Y><K><S><T><W><E><Y><Q><E><E><L><F><Q><D><I><V><D><L><K><I><K><N><R><R><E><E><L><D><L><P><T><S><N><Y><L><L><F><V><E><H><P><H><V><Y><T><L><G><K><S><G><D><L><E><N><L><L><L><N><E><K><Q><L><E><A><K><G><A><A><F><Y><K><I><N><R><G><G><D><I><T><Y><H><G><P><G><Q><I><V><G><Y><P><I><L><D... | Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.<BOP> | A5FIL6 |
Q6D9G4 | SSTT_PECAS | Na(+)/serine-threonine symporter | Pectobacterium | <M><E><T><Q><Q><S><R><F><L><Q><Y><I><T><R><G><S><L><V><Q><Q><I><L><L><G><L><A><A><G><I><I><L><A><S><L><S><T><Q><A><A><L><A><A><G><L><L><G><T><L><F><V><G><A><L><K><A><V><A><P><I><L><V><L><V><L><V><M><A><S><I><A><N><H><Q><Q><G><Q><K><T><N><I><R><P><V><L><F><L><Y><L><I><G><T><F><S><A><A><L><I><A><V><V><L><S><V><L><F><P><S... | Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).<BOP> | Q6D9G4 |
A9MNX5 | MDH_SALAR | Malate dehydrogenase | Salmonella | <M><K><V><A><V><L><G><A><A><G><G><I><G><Q><A><L><A><L><L><L><K><N><Q><L><P><S><G><S><E><L><S><L><Y><D><I><A><P><V><T><P><G><V><A><V><D><L><S><H><I><P><T><A><V><K><I><K><G><F><S><G><E><D><A><T><P><A><L><E><G><A><D><V><V><L><I><S><A><G><V><A><R><K><P><G><M><D><R><S><D><L><F><N><V><N><A><G><I><V><K><N><L><V><Q><Q><I><A><K... | Catalyzes the reversible oxidation of malate to oxaloacetate.<BOP> | A9MNX5 |
G1XU02 | AR281_ARTOA | Arthrosporol biosynthesis cluster protein AOL_s00215g281 | Orbilia oligospora | <M><S><Q><H><P><T><K><F><D><V><H><H><H><F><V><P><D><F><Y><V><E><A><L><E><A><N><G><G><D><P><S><G><W><T><I><P><K><W><T><L><E><S><S><E><T><L><M><E><N><I><G><I><G><T><T><I><F><S><M><T><A><P><G><P><S><I><H><K><D><P><S><E><A><A><S><L><A><R><K><T><N><T><F><A><A><A><V><R><D><S><N><P><Q><K><F><G><F><F><A><A><L><P><S><L><L><N><K... | 6-methylsalicylic acid decarboxylase; part of the gene cluster that mediates the biosynthesis of arthrosporols, metabolites that possess a novel hybrid carbon skeleton consisting of a polyketide-derived epoxycyclohexenol combined with a terpenoid-derived monocyclic sesquiterpenol substructure. Arthrosporols B and C are... | G1XU02 |
Q6PDI6 | MINY2_MOUSE | Protein FAM63B | Mus | <M><E><N><S><P><D><S><P><Q><P><L><E><L><G><V><A><A><G><R><V><S><P><P><E><G><R><R><R><G><G><R><E><A><E><D><G><P><A><G><R><A><V><D><S><G><G><Q><G><A><A><A><A><A><A><R><S><S><L><G><D><P><T><S><P><S><Q><L><G><C><G><A><G><S><D><L><K><D><G><A><S><S><S><P><A><A><S><E><V><P><S><R><G><Q><H><K><V><T><A><S><P><E><L><A><E><A><A><A... | Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins. Can also bind to polyubiquitin chains of different linkage types, including 'Lys-6', 'Lys-11', 'Lys-29', 'Lys-33' and 'Lys-63'. May play a regulatory role at the level of protein turnover.<BOP> | Q6PDI6 |
B2JIR9 | ACCA_PARP8 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha | Paraburkholderia | <M><K><T><T><F><L><D><F><E><Q><P><I><A><E><L><E><A><K><I><E><E><L><R><F><V><Q><D><D><S><A><V><D><I><S><E><E><I><E><R><L><S><K><K><S><Q><Q><L><T><K><D><L><Y><T><N><L><T><P><W><Q><V><S><Q><I><A><R><H><P><Q><R><P><Y><T><Q><D><Y><I><N><E><L><F><T><D><F><H><E><L><H><G><D><R><S><F><A><D><D><L><S><I><V><G><G><L><A><R><F><N><G... | Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.<BOP> | B2JIR9 |
C5A6P8 | PAN_THEGJ | Proteasome regulatory particle | Thermococcus | <M><G><S><F><D><E><V><S><H><D><T><G><Y><E><D><Y><I><T><F><L><K><R><R><I><R><Q><L><E><L><Q><V><R><T><L><E><A><D><K><E><R><L><E><R><E><L><S><R><L><R><T><E><M><S><R><L><R><Q><P><P><A><F><A><G><T><V><I><E><V><L><D><D><D><R><A><I><V><Q><N><Y><N><G><P><R><F><V><V><R><I><A><P><W><I><E><R><D><K><L><K><P><G><S><R><V><A><L><D><Q... | ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. ... | C5A6P8 |
A7HDZ5 | PLSX_ANADF | Phosphate-acyl-ACP acyltransferase | unclassified Anaeromyxobacter | <M><V><G><K><I><A><P><V><A><V><D><A><M><G><G><D><H><A><P><G><A><I><V><Q><G><A><I><N><A><A><R><K><G><L><P><I><L><L><V><G><P><E><A><R><L><R><D><E><L><A><R><H><R><A><G><H><A><L><P><I><E><V><H><H><A><G><E><V><V><E><M><D><D><H><P><G><Q><A><M><R><R><K><R><D><N><S><I><R><V><C><F><E><L><V><K><S><G><R><A><S><A><M><V><S><A><G><N... | Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.<BOP> | A7HDZ5 |
Q09094 | REC15_SCHPO | Meiotic recombination protein rec15 | Schizosaccharomyces | <M><S><Y><S><V><S><A><A><Q><L><W><S><R><K><L><A><M><Q><A><E><D><M><Q><Q><H><Q><K><S><Q><S><N><Q><I><A><S><C><L><A><E><M><N><T><K><Q><E><V><V><N><Q><T><I><G><Q><L><G><R><S><I><S><E><V><Q><Q><Q><N><S><Q><L><V><L><Q><S><L><N><Q><I><N><M><S><M><Q><Q><V><A><L><G><I><Q><D><Y><A><S><R><I><N><K><L><E><Q><T><M><S><D><M><N><L><K... | Required during the early stages of meiosis for meiotic recombination.<BOP> | Q09094 |
Q56731 | PDXB_SHESP | Erythronate-4-phosphate dehydrogenase | Shewanella | <K><L><K><D><K><T><V><G><I><V><G><A><G><N><T><G><S><A><V><A><K><C><L><Q><A><Y><G><V><T><V><L><L><H><D><P><V><I><Q><D><S><D><P><R><D><F><I><S><L><D><E><L><I><A><C><C><D><V><I><S><L><H><V><P><I><T><K><T><G><E><H><K><T><W><Y><L><F><D><E><A><R><L><N><S><L><K><Q><G><T><W><L><L><N><C><C><R><G><E><V><I><D><N><Q><A><L><I><K><V... | Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.<BOP> | Q56731 |
Q5ANB2 | DBP10_CANAL | ATP-dependent RNA helicase DBP10 | Candida | <M><S><D><D><E><A><F><D><I><A><G><S><L><A><L><K><D><E><D><D><Y><S><D><S><S><S><N><E><G><E><D><F><Q><D><E><I><I><P><S><D><D><E><K><E><P><S><P><P><P><K><K><K><S><K><P><N><P><Q><A><F><P><S><L><E><L><S><D><N><E><G><N><N><D><D><D><D><D><D><D><S><K><I><N><S><Y><F><I><N><N><N><P><T><A><K><K><A><K><A><G><S><F><A><S><F><G><L><T... | ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.<BOP> | Q5ANB2 |
A0RA12 | KDPA_BACAH | Potassium-translocating ATPase A chain | Bacillus cereus group | <M><I><W><V><A><V><V><I><T><M><L><L><F><I><L><V><A><K><P><T><G><I><Y><L><E><K><A><F><Q><G><S><K><K><L><D><K><V><F><G><P><F><E><K><L><I><F><K><I><T><G><V><K><E><Y><N><Q><T><W><K><Q><Y><A><L><S><L><V><L><L><N><G><F><M><I><V><V><V><Y><F><I><F><R><L><Q><G><V><L><P><L><N><P><A><H><I><E><G><M><E><P><T><L><A><F><N><T><A><I><S... | Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunne... | A0RA12 |
Q89A58 | DEOD_BUCBP | Purine nucleoside phosphorylase DeoD-type | Buchnera | <M><V><T><P><H><I><N><A><K><K><G><D><F><S><D><C><V><L><M><P><G><D><P><L><R><A><R><Y><I><A><K><N><Y><L><K><N><A><I><E><V><T><N><I><R><S><M><L><G><Y><T><G><R><Y><K><G><H><R><I><S><V><M><S><H><G><I><G><I><P><S><S><L><I><Y><V><K><E><L><V><S><E><Y><N><V><K><K><I><I><R><I><G><T><C><G><T><V><I><E><H><I><N><I><N><D><I><I><I><C... | Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.<BOP> | Q89A58 |
G8FZS4 | CX9A_CRACE | Cce9.1 | Crassispira | <A><D><N><H><A><R><V><A><G><P><R><A><V><A><S><G><R><Y><A><T><E><K><A><F><L><Q><M><M><T><R><G><S><C><G><L><P><C><H><E><N><R><R><C><G><W><A><C><Y><C><D><D><G><I><C><K><P><L><R><V> | Crassispirid snail peptide that induces sleep-like symptoms in young mice (12 and 14 days) and hyperactivity in older mice (16 days), when intracranially injected.<BOP> | G8FZS4 |
Q8XHD3 | GLPK_CLOPE | Glycerokinase | Clostridium | <M><K><K><Y><I><V><A><L><D><Q><G><T><T><S><S><R><A><I><I><F><D><K><E><Q><N><I><I><G><V><S><Q><K><E><F><N><Q><I><Y><P><R><E><G><W><V><E><H><D><P><M><E><I><W><A><T><Q><Y><S><V><L><Q><E><V><M><A><K><C><N><I><T><Q><E><N><I><A><A><I><G><I><T><N><Q><R><E><T><T><I><V><W><D><K><N><T><G><V><P><I><Y><N><A><I><V><W><Q><C><R><R><T... | Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.<BOP> | Q8XHD3 |
B3PLW7 | EFTS_META1 | Elongation factor Ts | Metamycoplasma | <M><S><P><D><L><K><K><L><K><E><L><R><E><R><T><N><S><G><L><L><D><C><K><N><A><L><E><A><T><D><N><D><I><E><K><A><I><K><W><L><Q><E><N><G><I><I><K><A><A><K><K><S><A><R><I><A><A><E><G><I><T><K><A><Y><I><K><D><N><V><A><V><L><F><E><L><N><A><E><T><D><F><V><A><R><N><Q><L><F><I><D><L><A><N><K><I><Q><D><A><L><A><A><N><D><F><S><D><I... | Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.<BOP> | B3PLW7 |
B1XLR5 | GUAA_SYNP2 | Glutamine amidotransferase | unclassified Synechococcus | <M><L><N><V><T><T><T><P><L><Q><K><P><I><D><A><T><N><T><G><N><S><L><Q><R><Q><I><I><V><I><L><D><F><G><S><Q><Y><S><E><L><I><A><R><R><I><R><E><T><E><V><Y><S><E><V><I><S><Y><R><T><S><A><E><Q><L><R><Q><L><N><P><S><G><I><I><L><S><G><G><P><S><S><V><Y><D><D><Y><A><P><A><C><D><P><E><I><W><N><L><G><I><P><V><L><G><V><C><Y><G><M><Q... | Catalyzes the synthesis of GMP from XMP.<BOP> | B1XLR5 |
B1MX40 | G6PI_LEUCK | Phosphohexose isomerase | Leuconostoc | <M><A><H><I><T><F><D><T><K><N><I><E><N><F><V><A><A><H><E><F><S><E><M><Q><P><L><I><T><M><A><D><E><Q><L><R><H><R><T><G><A><G><A><E><Y><S><D><W><I><T><L><P><T><D><Y><D><K><A><E><F><S><R><I><Q><A><A><A><K><Q><I><Q><S><D><S><K><I><L><V><V><I><G><I><G><G><S><Y><L><G><A><K><M><A><V><D><F><L><N><P><M><F><N><N><E><L><A><D><D><Q... | Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.<BOP> | B1MX40 |
P36571 | BIOC_SERMA | Biotin synthesis protein BioC | Serratia | <M><T><S><A><N><D><T><V><N><K><Q><A><V><A><S><A><F><S><R><A><A><G><S><Y><D><A><A><A><A><L><Q><R><D><V><G><E><R><L><L><G><M><G><S><S><H><P><G><E><Q><L><L><D><A><G><C><G><T><G><Y><F><S><R><M><W><R><E><R><G><K><R><V><T><A><L><D><L><A><P><G><M><L><D><V><A><R><Q><R><Q><A><A><H><H><Y><L><L><G><D><I><E><Q><V><P><L><P><D><A><A... | Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.<BOP> | P36571 |
Q1QN08 | RS13_NITHX | 30S ribosomal protein S13 | Nitrobacter | <M><A><R><I><A><G><V><N><I><P><T><N><K><R><V><V><I><A><L><Q><Y><I><H><G><I><G><Q><K><N><A><A><E><I><I><D><K><V><K><I><P><A><D><R><R><V><S><Q><L><S><D><Q><E><V><L><Q><I><R><E><V><I><D><R><D><Y><L><V><E><G><D><L><R><R><E><V><G><I><N><I><K><R><L><M><D><L><G><C><Y><R><G><L><R><H><R><R><G><L><P><V><R><G><Q><R><T><H><T><N><A... | Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.<... | Q1QN08 |
Q24475 | RPR_DROME | Protein reaper | Sophophora | <M><A><V><A><F><Y><I><P><D><Q><A><T><L><L><R><E><A><E><Q><K><E><Q><Q><I><L><R><L><R><E><S><Q><W><R><F><L><A><T><V><V><L><E><T><L><R><Q><Y><T><S><C><H><P><K><T><G><R><K><S><G><K><Y><R><K><P><S><Q> | Activator of apoptosis, as well as grim and hid, that acts on the effector Dredd.<BOP> | Q24475 |
Q74FG0 | RNH2_GEOSL | Ribonuclease HII | Geobacter | <M><S><L><T><L><F><D><H><E><P><Q><P><A><V><W><D><F><E><S><R><A><A><R><R><G><Y><R><T><I><A><G><I><D><E><A><G><R><G><P><L><A><G><P><V><V><A><A><A><V><I><L><P><F><G><T><D><L><P><G><V><D><D><S><K><K><L><T><P><A><R><R><D><D><L><F><T><L><I><Q><G><T><A><L><A><I><G><V><G><V><A><D><H><K><V><I><D><R><I><N><I><L><Q><A><T><L><A><A... | Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP> | Q74FG0 |
O48039 | CYB_CORHE | Ubiquinol-cytochrome-c reductase complex cytochrome b subunit | Corallus | <M><P><H><Q><Q><M><L><M><L><F><G><L><L><P><V><A><T><N><I><S><T><W><W><N><F><G><S><M><L><L><T><C><S><A><L><Q><V><L><T><G><F><F><L><A><V><H><Y><T><A><N><I><D><L><A><F><S><S><V><V><H><I><M><R><D><V><P><Y><G><W><M><M><Q><N><L><H><A><M><G><A><S><M><F><F><I><C><I><Y><I><H><I><A><R><G><L><Y><Y><G><S><Y><L><N><K><E><T><W><L><S... | Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is... | O48039 |
A5IXK9 | GLYA_MYCAP | Serine hydroxymethyltransferase | Mycoplasmopsis | <M><Y><K><K><I><S><M><N><D><K><E><I><E><H><A><I><N><N><E><V><D><R><Q><N><E><H><I><E><L><I><A><S><E><N><Y><V><S><E><D><V><L><T><A><V><G><S><V><L><T><N><K><Y><G><E><G><Y><P><G><K><R><Y><Y><G><G><C><E><N><V><D><V><V><E><T><L><A><I><E><R><L><K><K><L><F><G><V><K><F><A><N><V><Q><P><Y><S><G><S><V><A><N><A><A><A><L><A><T><L><A... | Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent a... | A5IXK9 |
B2SH69 | RUVC_FRATM | Holliday junction resolvase RuvC | Francisella | <M><V><I><L><G><I><D><P><G><S><R><I><T><G><F><G><V><I><K><V><Q><D><N><K><I><Y><Y><V><A><S><G><C><I><R><I><T><E><I><T><T><P><K><R><L><K><Q><I><A><D><G><I><T><Q><I><I><N><I><Y><A><P><T><E><A><A><I><E><Q><I><F><M><F><Q><N><P><M><G><A><I><K><L><G><Q><A><R><G><V><A><M><C><T><L><A><I><N><N><L><E><V><S><E><Y><S><A><K><Q><I><K... | Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.<BOP> | B2SH69 |
Q82NI4 | UPPP1_STRAW | Undecaprenyl pyrophosphate phosphatase 1 | Streptomyces | <M><S><V><I><N><V><G><Q><A><V><V><L><G><A><V><E><G><V><T><E><F><L><P><V><S><S><T><G><H><L><K><I><T><E><G><L><M><G><I><P><V><D><D><N><A><V><V><G><F><S><A><V><I><Q><V><G><A><I><A><A><V><L><V><Y><F><F><K><D><I><V><R><I><V><S><A><W><G><R><G><L><R><N><R><D><E><R><H><H><H><D><Y><K><F><A><W><W><V><I><Y><A><T><I><P><I><V><I><V... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | Q82NI4 |
B2SFE5 | RL19_FRATM | 50S ribosomal protein L19 | Francisella | <M><K><N><K><F><V><E><L><V><E><K><S><Q><L><R><T><D><L><P><E><F><N><P><G><D><S><I><T><V><N><L><W><I><K><E><G><D><K><Q><R><I><Q><A><F><K><G><F><V><L><R><K><R><N><R><G><L><H><S><A><F><T><V><R><K><M><S><S><G><M><G><V><E><R><T><F><Q><T><H><S><P><L><I><D><S><I><I><V><E><K><R><A><D><V><R><R><A><K><L><Y><Y><M><R><G><L><T><G><K... | This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.<BOP> | B2SFE5 |
Q7VH33 | LEU3_HELHP | Beta-IPM dehydrogenase | Helicobacter | <M><Q><K><R><I><A><V><I><Y><G><D><G><I><G><K><E><V><I><T><Q><A><L><K><I><L><K><A><V><A><K><K><Y><E><H><T><F><I><F><E><E><V><L><A><G><G><A><A><I><D><E><C><G><E><C><L><P><M><K><S><L><Q><I><C><K><Q><S><D><S><V><L><L><G><A><V><G><G><P><K><W><D><N><E><P><S><H><N><R><P><E><K><A><L><L><T><L><R><K><E><L><G><L><F><A><N><I><R><P... | Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.<BOP> | Q7VH33 |
B2J938 | HRCA_NOSP7 | Heat-inducible transcription repressor HrcA | Nostoc | <M><E><V><Q><L><T><N><R><Q><Q><H><I><L><W><A><T><V><R><H><Y><I><A><T><A><E><P><V><G><S><K><A><L><V><E><E><Y><D><L><G><V><S><S><A><T><I><R><N><V><M><G><V><L><E><K><S><G><L><L><Y><Q><P><H><A><S><A><G><R><V><P><S><D><S><G><Y><R><I><Y><V><D><Q><L><I><T><P><S><L><R><S><R><S><V><S><Q><T><D><A><T><R><T><E><T><L><G><R><E><I><E... | Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.<BOP> | B2J938 |
Q9SXC9 | MNS5_ARATH | Alpha-mannosidase I MNS5 | Arabidopsis | <M><S><C><P><I><H><P><R><R><L><F><L><C><L><L><I><S><L><T><F><F><V><V><D><P><S><S><Q><H><I><E><V><K><K><K><Q><M><R><E><K><V><R><E><M><F><Y><H><A><Y><D><N><Y><M><T><Y><A><F><P><H><D><E><L><K><P><L><T><K><S><F><T><D><S><L><S><E><L><G><N><L><K><L><E><H><L><P><T><D><Y><N><G><S><A><V><T><L><V><E><S><L><S><S><L><A><I><L><G><N... | Can convert Man(9)GlcNAc(2) and Man(8)GlcNAc(2) into N-glycans with a terminal alpha-1,6-linked Man residue in the C-branch. Functions in the formation of unique N-glycan structures that are specifically recognized by components of the endoplasmic reticulum-associated degradation (ERAD) machinery, which leads to the de... | Q9SXC9 |
P04640 | OSTCN_RAT | Gamma-carboxyglutamic acid-containing protein | Rattus | <M><R><T><L><S><L><L><T><L><L><A><L><T><A><F><C><L><S><D><L><A><G><A><K><P><S><D><S><E><S><D><K><A><F><M><S><K><Q><E><G><S><K><V><V><N><R><L><R><R><Y><L><N><N><G><L><G><A><P><A><P><Y><P><D><P><L><E><P><H><R><E><V><C><E><L><N><P><N><C><D><E><L><A><D><H><I><G><F><Q><D><A><Y><K><R><I><Y><G><T><T><V> | Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.<BOP> | P04640 |
Q6GCQ0 | PFLB_STAAS | Pyruvate formate-lyase | Staphylococcus | <M><L><E><T><N><K><N><H><A><T><A><W><Q><G><F><K><N><G><R><W><N><R><H><V><D><V><R><E><F><I><Q><L><N><Y><T><L><Y><E><G><N><D><S><F><L><A><G><P><T><E><A><T><S><K><L><W><E><Q><V><M><Q><L><S><K><E><E><R><E><R><G><G><M><W><D><M><D><T><K><V><A><S><T><I><T><S><H><D><A><G><Y><L><D><K><D><L><E><T><I><V><G><V><Q><T><E><K><P><F><K... | Catalyzes the conversion of pyruvate to formate and acetyl-CoA.<BOP> | Q6GCQ0 |
B5ZWQ2 | DNAK_RHILW | Heat shock protein 70 | Rhizobium | <M><A><K><V><I><G><I><D><L><G><T><T><N><S><C><V><A><V><M><D><G><K><D><A><K><V><I><E><N><A><E><G><A><R><T><T><P><S><M><V><A><F><S><D><D><G><E><R><L><V><G><Q><P><A><K><R><Q><A><V><T><N><P><T><N><T><L><F><A><V><K><R><L><I><G><R><R><Y><E><D><P><T><V><E><K><D><K><H><L><V><P><F><T><I><V><K><G><D><N><G><D><A><W><V><E><A><N><G... | Acts as a chaperone.<BOP> | B5ZWQ2 |
P37446 | PA1_KLEPN | Phosphatidylcholine 1-acylhydrolase | Klebsiella | <M><R><I><S><L><A><C><L><A><A><L><C><A><L><P><A><G><V><M><A><Q><D><A><S><V><H><D><K><P><A><V><R><G><S><I><I><A><N><L><L><Q><D><H><D><N><P><F><L><L><Y><P><Y><E><S><N><Y><L><L><Y><T><W><T><S><D><L><N><K><E><A><I><R><S><Y><D><W><A><E><N><A><R><K><D><E><V><K><F><Q><L><S><L><A><F><P><L><W><R><G><I><L><G><D><N><S><L><L><G><A... | Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.<BOP> | P37446 |
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