accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
B0K1T5
CODY_THEPX
GTP-sensing transcriptional pleiotropic repressor CodY
unclassified Thermoanaerobacter
<M><S><T><L><L><E><K><T><R><K><V><N><R><I><L><Q><K><T><G><I><Q><P><V><D><F><N><E><M><A><S><I><L><K><D><V><I><E><A><N><V><Y><I><L><S><R><K><G><K><V><L><G><Y><S><I><L><K><D><Y><G><N><D><I><F><A><Q><S><K><I><I><P><E><E><Y><N><D><K><L><L><R><V><T><E><T><L><A><N><D><K><G><N><L><F><K><E><D><K><I><L><S><D><L><I><L><T><I><V><P...
DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer b...
B0K1T5
Q4L837
GLMM_STAHJ
Phosphoglucosamine mutase
Staphylococcus
<M><V><K><Y><F><G><T><D><G><V><R><G><I><A><N><K><E><L><T><P><E><L><A><F><K><L><G><R><Y><G><G><Y><V><L><A><H><N><E><G><A><D><R><P><K><V><L><V><G><R><D><T><R><V><S><G><E><M><L><E><S><A><L><I><S><G><L><A><S><I><G><A><E><V><M><R><L><G><V><I><S><T><P><G><V><A><Y><L><T><R><E><M><G><A><E><L><G><V><M><I><S><A><S><H><N><P><V><A...
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.<BOP>
Q4L837
Q03VW4
GLMM_LEUMM
Phosphoglucosamine mutase
Leuconostoc
<M><S><E><F><N><L><K><Y><F><G><T><D><G><V><R><G><V><A><N><K><T><L><T><P><E><L><A><F><R><L><G><R><T><G><G><A><I><L><T><R><H><A><N><D><E><N><K><K><P><V><V><I><V><G><R><D><T><R><I><S><G><E><M><L><Q><Q><A><I><I><A><G><F><L><S><V><G><I><D><V><L><R><L><G><V><I><T><T><P><A><V><A><F><L><V><Q><N><L><E><A><D><A><G><V><Q><I><T><A...
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.<BOP>
Q03VW4
T1SFR8
PPR3C_CLABA
Protein phosphatase 1 regulatory subunit 3C
Clarias
<M><P><V><D><M><A><V><Q><L><Y><I><T><S><S><P><P><L><H><H><R><F><L><S><S><Y><K><D><Y><R><V><R><N><L><I><S><V><N><C><K><P><L><R><P><C><I><N><T><K><N><T><H><N><T><S><L><N><P><P><C><S><V><W><K><A><P><E><P><K><A><K><K><K><V><V><F><A><D><S><K><G><M><S><L><T><A><V><R><V><F><S><P><C><E><N><K><K><S><D><S><Q><V><Q><F><Q><L><P><K...
Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.<BOP>
T1SFR8
B3PMB4
RSMH_META1
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Metamycoplasma
<M><E><I><K><S><D><G><T><Y><V><D><L><T><L><G><R><A><G><H><S><L><E><I><L><K><K><L><I><N><G><R><L><I><C><F><D><K><D><N><E><A><I><K><E><S><Y><K><K><L><Q><K><I><S><P><N><F><T><L><I><Q><N><D><F><R><F><L><K><A><E><L><E><K><L><G><I><N><E><V><D><G><I><L><A><D><L><G><V><S><S><P><Q><I><D><D><P><T><R><G><F><S><Y><S><Q><E><G><P><L...
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.<BOP>
B3PMB4
Q1J652
OBG_STRPF
GTP-binding protein Obg
Streptococcus
<M><S><M><F><L><D><T><A><K><I><S><V><Q><A><G><R><G><G><D><G><M><V><A><F><R><R><E><K><Y><V><P><N><G><G><P><W><G><G><D><G><G><K><G><G><S><V><I><F><R><V><D><E><G><L><R><T><L><M><D><F><R><Y><N><R><K><F><K><A><K><S><G><E><K><G><M><T><K><G><M><H><G><R><G><A><E><D><L><I><V><F><V><P><Q><G><T><T><V><R><D><A><E><T><G><K><V><I><T...
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.<B...
Q1J652
Q6H3C9
PA2AC_TRIST
Phosphatidylcholine 2-acylhydrolase
Trimeresurus
<M><R><T><L><W><I><M><A><V><L><L><L><G><V><E><G><S><L><I><Q><F><E><T><L><I><M><K><V><A><K><K><S><G><M><F><S><Y><S><A><Y><G><C><Y><C><G><W><G><G><Q><G><Q><P><Q><D><A><T><D><R><C><C><F><V><H><D><C><C><Y><G><K><V><T><G><C><D><P><K><M><D><I><Y><T><Y><S><E><E><N><G><D><I><V><C><G><G><D><D><P><C><R><K><A><V><C><E><C><D><K><A...
Snake venom phospholipase A2 (PLA2) that shows a moderate inhibition of ADP-induced human platelet aggregation when tested on platelet rich plasma. Exhibits high hydrolytic activities and prefers the anionic micelles (dPPC with deoxycholate) to the zwitterionic micelles (dPPC with Triton X-100). PLA2 catalyzes the calc...
Q6H3C9
A6WXC3
ACCA_BRUA4
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
Brucella
<M><Y><N><Y><L><D><F><E><K><P><V><A><D><L><E><G><Q><I><L><E><L><K><K><L><A><Q><E><Q><G><S><V><E><M><S><D><E><I><R><R><L><E><K><R><S><A><D><A><L><K><D><I><Y><R><K><L><T><P><W><Q><K><T><Q><I><A><R><H><P><D><R><P><H><C><L><E><Y><I><D><R><L><F><T><E><F><T><P><L><A><G><D><R><K><F><A><N><D><E><A><L><Q><T><G><F><G><R><F><N><G...
Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.<BOP>
A6WXC3
Q48JS3
SYT_PSE14
Threonyl-tRNA synthetase
Pseudomonas
<M><P><T><I><T><L><P><D><G><S><Q><R><S><F><D><H><V><V><S><V><A><D><V><A><L><S><I><G><A><G><L><A><K><A><T><V><A><G><K><V><D><G><K><L><V><D><A><C><D><L><I><E><N><D><A><S><L><Q><I><I><T><P><K><D><Q><E><G><L><E><I><I><R><H><S><C><A><H><L><V><G><H><A><V><K><Q><L><Y><P><T><A><K><M><V><I><G><P><V><I><D><D><G><F><Y><Y><D><I><A...
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr).<BOP>
Q48JS3
Q01497
PEX3_PICAN
Peroxisomal membrane protein PER9
Ogataea
<M><F><Q><Y><C><R><D><L><V><S><R><H><K><K><K><L><L><F><G><T><G><V><I><A><V><S><Y><A><V><S><S><F><V><S><N><K><L><A><E><L><N><E><R><L><K><E><E><N><F><A><K><E><Q><I><K><R><R><F><K><Q><T><Q><N><D><C><Y><M><T><F><L><S><L><L><P><V><L><T><E><P><I><Y><E><A><L><K><V><E><E><I><T><R><E><L><Q><N><K><R><F><E><R><Q><K><A><K><N><A><P...
Involved in peroxisome proliferation and/or membrane biosynthesis. Plays a role in the maintenance of the peroxisomal membrane in vivo.<BOP>
Q01497
A0Q060
MRAY_CLONN
UDP-MurNAc-pentapeptide phosphotransferase
Clostridium
<M><S><L><M><I><Y><S><V><L><V><A><F><V><V><S><L><I><Q><G><P><I><L><I><P><L><L><H><K><F><K><F><G><Q><N><I><R><S><E><G><P><E><S><H><K><K><K><S><G><T><P><T><M><G><G><V><I><F><I><I><S><S><V><I><T><V><F><V><V><S><R><H><P><S><F><E><T><K><L><A><I><F><A><F><V><A><F><G><I><I><G><L><I><D><D><S><L><K><I><I><H><K><E><N><E><G><L><K...
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I...
A0Q060
Q7VLK1
USPA_HAEDU
Universal stress protein A homolog
Haemophilus
<M><Y><K><H><I><L><V><A><V><D><L><S><E><E><S><L><I><L><L><R><K><G><A><G><L><A><E><K><C><G><A><K><L><S><L><I><H><V><D><V><N><F><S><D><L><Y><T><G><L><I><D><I><N><M><S><S><V><Q><D><G><V><I><E><E><T><T><K><A><L><D><E><L><A><L><K><I><D><Y><P><V><S><Q><R><L><N><G><T><G><D><F><S><Q><V><L><E><E><A><V><A><K><Y><Q><I><D><L><L><I...
Required for resistance to DNA-damaging agents.<BOP>
Q7VLK1
A5F2H3
BIOB_VIBC3
Biotin synthase
Vibrio
<M><E><V><R><H><N><W><T><V><A><E><V><K><A><L><L><D><K><P><F><M><D><L><L><F><E><A><Q><Q><V><H><R><L><H><H><P><H><N><H><V><Q><V><S><T><L><L><S><I><K><T><G><A><C><P><E><D><C><K><Y><C><P><Q><S><A><H><Y><R><T><D><V><D><K><E><R><L><M><E><V><E><R><V><L><D><A><A><Q><K><A><K><N><S><G><S><T><R><F><C><M><G><A><A><W><K><N><P><K><E...
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.<BOP>
A5F2H3
P46217
RPO11_SULAC
DNA-directed RNA polymerase subunit L
Sulfolobus
<M><E><I><K><V><I><K><E><E><Q><N><Y><L><E><L><Q><I><D><G><E><E><H><T><I><G><N><L><L><K><G><M><L><L><K><V><P><G><V><K><F><A><A><Y><S><L><P><H><P><L><I><T><S><I><T><I><K><I><L><T><D><G><S><I><S><A><R><E><A><L><I><K><A><I><E><L><A><E><N><Y><A><N><L><F><I><D><E><V><K><K><I>
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
P46217
Q82TC0
AROK_NITEU
Shikimate kinase
Nitrosomonas
<M><H><F><R><Y><N><Y><R><M><Q><R><S><K><T><P><N><T><K><N><S><D><T><G><S><I><P><G><N><I><I><L><I><G><M><M><G><S><G><K><T><T><V><G><K><L><L><A><N><L><V><G><K><T><F><I><D><I><D><H><E><I><Q><R><R><T><G><V><G><I><P><V><I><F><E><I><E><G><E><A><G><F><R><K><R><E><S><E><V><L><R><D><I><V><R><Q><Q><N><I><V><L><A><T><G><G><G><A><I...
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.<BOP>
Q82TC0
P61666
MUTS_DESVH
DNA mismatch repair protein MutS
Desulfovibrio
<M><T><N><P><S><P><K><L><T><P><M><F><E><Q><Y><L><R><I><K><E><D><Y><P><D><A><L><L><F><Y><R><M><G><D><F><Y><E><L><F><F><D><D><A><E><T><T><A><R><E><L><Q><I><A><L><T><C><R><N><P><N><A><E><L><K><A><P><M><C><G><V><P><Y><H><A><V><E><G><Y><I><S><Q><L><L><D><K><G><Y><R><V><A><I><C><E><Q><I><E><D><P><K><E><A><K><G><L><V><K><R><A...
This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.<BOP>
P61666
M1VV66
TCPD_CLAP2
Tyrosine O-prenyltransferase tcpD
Claviceps
<M><P><F><M><F><E><T><I><L><S><R><V><K><W><T><A><N><T><L><V><A><R><L><T><T><L><Y><E><Y><E><Y><P><R><T><A><K><E><E><T><G><I><D><K><E><Y><H><I><K><L><W><D><E><D><I><G><A><M><L><V><S><M><M><R><L><A><G><Y><S><E><Q><S><Q><K><T><H><R><I><F><F><K><E><Q><V><A><R><S><L><G><L><Y><P><T><T><Y><P><H><Q><S><A><W><E><S><F><M><T><D><D...
4-O-dimethylallyl-L-tyrosine synthase; part of the gene cluster that mediates the biosynthesis of an unusual class of epipolythiodioxopiperazines (ETPs) lacking the reactive thiol group important for toxicity . Firstly, L-tyrosine is prenylated by tcpD, before undergoing condensation with L-glycine in a reaction cataly...
M1VV66
Q6D7L7
LPTE_PECAS
LPS-assembly lipoprotein LptE
Pectobacterium
<M><R><H><R><L><F><T><L><V><L><G><L><A><V><L><I><T><A><G><C><G><F><H><L><R><G><T><T><Q><V><P><A><Q><L><Q><T><L><V><L><D><S><S><D><P><Y><G><P><L><T><R><A><V><R><E><Q><L><R><L><S><D><V><K><I><V><D><D><A><T><R><Q><D><I><P><S><L><R><V><L><S><S><S><E><T><R><D><T><V><S><I><F><Q><D><G><K><T><A><E><Y><Q><M><V><L><T><L><Q><A><Q...
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.<BOP>
Q6D7L7
Q71SG7
GCNT4_DANRE
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4
Danio
<M><R><R><C><A><V><L><H><R><L><R><C><K><F><Y><V><F><V><V><S><L><F><V><V><V><K><L><V><Y><L><K><I><S><M><D><N><S><I><Y><I><E><P><Y><G><V><T><R><R><S><L><K><P><Q><P><L><D><G><I><N><C><T><A><I><Y><D><L><E><P><V><E><I><G><K><S><L><E><M><R><R><K><K><I><V><E><V><D><D><G><R><I><A><S><F><T><A><D><C><K><S><Y><I><E><Q><R><R><Y><N...
Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis.<BOP>
Q71SG7
Q8MJK1
CBY1_BOVIN
PKD2 interactor, Golgi and endoplasmic reticulum-associated 1
Bos
<M><P><L><F><G><S><T><F><S><P><K><K><T><P><P><R><K><S><A><S><L><S><N><L><H><N><L><D><R><S><T><R><E><V><E><L><G><L><D><Y><G><T><P><T><M><N><L><A><G><Q><S><L><K><F><E><N><G><Q><W><I><A><E><T><G><I><S><G><G><V><D><R><R><E><A><Q><R><L><R><R><R><N><Q><Q><L><E><E><E><N><N><L><L><R><L><K><V><D><I><L><L><D><M><L><S><E><T><T><A...
Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellu...
Q8MJK1
Q5NNW5
ADE_ZYMMO
Adenine aminohydrolase
Zymomonas
<M><N><N><L><I><K><F><I><A><A><L><P><K><A><E><L><H><L><H><I><E><G><S><L><E><P><E><L><M><F><E><L><A><K><R><N><K><V><T><L><P><F><P><D><V><E><S><V><K><A><A><Y><N><F><N><N><L><Q><E><F><L><D><I><Y><Y><Q><G><T><N><V><L><K><T><E><E><D><F><C><D><L><A><M><A><Y><F><Y><R><A><H><R><D><N><V><L><H><S><E><I><F><F><D><P><Q><S><H><T><E...
Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.<BOP>
Q5NNW5
B5YG33
RS8_THEYD
30S ribosomal protein S8
Thermodesulfovibrio
<M><I><T><D><P><I><S><D><M><L><T><R><I><R><N><A><I><K><V><K><A><D><K><V><D><I><P><A><S><R><M><K><I><E><I><S><K><I><L><K><E><E><G><F><I><K><S><Y><K><I><I><K><D><K><K><Q><G><I><I><R><I><N><L><K><Y><T><S><E><G><D><S><V><I><S><N><L><Q><R><I><S><K><P><G><R><R><V><Y><V><S><K><D><E><I><P><H><V><M><G><G><L><G><V><A><I><L><T><T...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.<BOP>
B5YG33
Q9D9H3
MB3L1_MOUSE
Methyl-CpG-binding domain protein 3-like 1
Mus
<M><G><K><T><S><Q><R><K><Q><C><D><C><E><N><P><S><K><P><C><L><S><T><S><I><P><L><R><M><S><S><Y><T><F><K><R><P><V><T><K><I><T><S><H><L><G><N><E><V><R><Y><Y><Q><W><E><E><T><L><E><K><P><E><Q><A><C><W><Q><K><R><L><Q><G><L><Q><A><Y><S><S><A><G><E><L><L><S><T><S><D><L><A><K><T><L><K><D><L><T><S><T><D><T><V><A><S><A><S><D><T><Q...
Transcriptional repressor.<BOP>
Q9D9H3
Q7S2H8
TPC1_NEUCR
Mitochondrial thiamine pyrophosphate carrier 1
Neurospora
<M><S><G><K><A><E><R><L><K><D><E><G><S><R><L><Q><V><T><A><A><G><A><T><A><G><L><I><S><R><F><V><I><A><P><L><D><V><V><K><I><R><L><Q><L><Q><H><H><S><L><S><D><P><L><L><H><Q><R><R><A><E><I><I><G><G><G><P><V><Y><K><G><T><L><P><T><I><R><H><I><L><R><T><E><G><L><T><G><L><W><K><G><N><I><P><A><E><L><L><Y><V><S><Y><A><A><V><Q><F><T...
Mitochondrial transporter that mediates uptake of thiamine pyrophosphate (ThPP) into mitochondria.<BOP>
Q7S2H8
B4F0D8
MNMG_PROMH
Glucose-inhibited division protein A
Proteus
<M><F><Y><P><E><H><F><D><V><I><V><I><G><G><G><H><A><G><T><E><A><A><M><A><A><A><R><M><G><R><Q><T><L><L><L><T><H><N><I><D><T><L><G><Q><M><S><C><N><P><A><I><G><G><I><G><K><G><H><L><V><K><E><I><D><A><M><G><G><L><M><A><T><A><I><D><H><A><G><I><Q><F><R><T><L><N><A><S><K><G><P><A><V><R><A><T><R><A><Q><A><D><R><V><L><Y><R><Q><A...
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.<BOP>
B4F0D8
B2IU73
GLMU_NOSP7
Glucosamine-1-phosphate N-acetyltransferase
Nostoc
<M><V><V><V><A><I><L><A><A><G><R><G><T><R><M><K><S><R><L><P><K><V><L><H><S><L><G><G><Q><S><L><V><E><R><V><I><E><S><V><E><P><L><S><P><S><R><R><I><V><I><V><G><Y><Q><S><E><E><V><Q><T><A><M><H><S><I><P><N><L><E><F><V><E><Q><T><V><Q><L><G><T><G><H><A><I><Q><Q><L><L><P><H><L><K><D><Y><T><G><D><L><L><I><L><N><G><D><L><P><L><I...
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted ...
B2IU73
Q9KDX6
GLGA_HALH5
Starch [bacterial glycogen] synthase
Halalkalibacterium (ex Joshi et al. 2022)
<M><N><V><L><H><V><A><S><E><C><N><P><F><F><K><T><G><G><L><A><D><V><L><G><S><L><P><K><A><L><I><K><Q><G><I><N><V><S><V><I><L><P><K><Y><G><H><L><S><D><E><W><Q><N><Q><L><T><L><K><K><S><F><T><V><S><V><T><W><R><N><Q><Y><C><G><L><E><Q><F><V><D><Q><G><V><T><Y><Y><F><I><D><N><E><Y><Y><F><K><R><E><R><L><Y><G><Y><L><D><E><A><E><R...
Synthesizes alpha-1,4-glucan chains using ADP-glucose.<BOP>
Q9KDX6
A6GWB6
SYD_FLAPJ
Aspartyl-tRNA synthetase
Flavobacterium
<M><Y><R><S><H><N><C><G><E><L><N><A><T><H><I><N><K><E><V><T><L><A><G><W><V><Q><K><S><R><D><K><G><F><M><N><W><V><D><L><R><D><R><Y><G><I><T><Q><L><M><F><D><E><S><R><S><D><K><T><V><F><E><L><A><K><T><L><G><R><E><F><V><I><Q><V><K><G><T><V><I><E><R><E><A><K><N><K><N><I><S><T><G><E><I><E><I><L><V><T><Q><M><T><I><L><N><S><S><L...
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).<BOP>
A6GWB6
Q2S8W2
PANC_HAHCH
Pantoate-activating enzyme
Hahella
<M><I><T><I><H><R><V><K><D><L><R><A><A><I><R><Q><Q><R><T><Q><G><K><R><I><G><L><V><P><T><M><G><N><L><H><A><G><H><V><S><L><V><K><Q><A><K><E><L><C><D><Y><V><V><T><S><I><F><V><N><P><L><Q><F><G><A><N><E><D><L><D><K><Y><P><R><T><L><D><A><D><K><E><K><L><V><A><A><G><N><H><L><L><F><T><P><E><V><S><Q><L><Y><P><E><G><L><E><R><H><T...
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<BOP>
Q2S8W2
B2I3A5
LGT_ACIBC
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase
Acinetobacter calcoaceticus/baumannii complex
<M><L><T><Y><P><N><I><D><P><V><A><I><H><L><G><P><L><Q><V><H><W><Y><G><L><M><Y><L><L><A><F><L><C><A><W><G><L><A><S><Y><R><A><K><Q><R><D><G><W><T><S><D><M><V><S><D><L><V><F><Y><G><A><L><G><V><V><L><G><G><R><I><G><Y><V><L><F><Y><E><F><D><K><F><L><E><N><P><I><W><L><F><Q><V><W><T><G><G><M><S><F><H><G><G><F><L><G><V><M><I><A...
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.<BOP>
B2I3A5
Q8ZST5
PSB2_PYRAE
Proteasome core protein PsmB 2
Pyrobaculum
<M><G><E><E><V><Q><I><G><A><T><A><V><G><I><K><A><K><D><G><V><V><L><A><A><E><K><R><V><S><Y><G><F><Y><T><L><S><S><A><G><K><K><V><F><V><I><D><D><K><L><A><I><A><S><A><G><I><I><A><D><M><Q><T><L><A><K><I><L><K><L><N><A><K><A><Y><E><L><E><M><K><R><K><P><S><T><H><S><M><A><R><L><L><S><V><I><M><F><S><R><R><F><M><P><F><F><A><E><V...
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.<BOP>
Q8ZST5
A4TBE2
SEPF_MYCGI
Cell division protein SepF
Mycolicibacterium
<M><S><T><L><H><K><V><K><A><Y><F><G><M><A><P><M><D><E><Y><E><D><D><Y><Y><E><D><D><D><R><G><P><A><P><R><G><Y><R><R><P><R><E><D><R><F><E><D><E><G><Y><A><P><R><G><Y><D><G><H><P><E><D><R><R><R><D><Y><D><E><P><P><A><Y><R><A><G><L><A><G><G><M><P><G><G><F><D><D><A><R><F><E><A><R><M><R><A><P><R><E><F><D><R><T><P><P><R><F><G><A...
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.<BOP>
A4TBE2
Q4QK57
POTA_HAEI8
Spermidine/putrescine import ATP-binding protein PotA
Haemophilus
<M><E><N><Q><P><Q><N><K><P><I><I><E><L><R><S><I><K><K><S><Y><G><S><N><T><I><I><N><D><F><N><L><A><I><N><N><G><E><F><V><T><I><L><G><P><S><G><C><G><K><T><T><V><L><R><L><L><A><G><L><E><E><L><D><S><G><S><I><I><L><D><G><E><D><I><T><N><V><P><A><E><K><R><H><I><N><T><V><F><Q><S><Y><A><L><F><P><H><M><T><I><F><E><N><V><A><F><G><L...
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.<BOP>
Q4QK57
Q5WTA1
MIAA_LEGPL
Isopentenyl-diphosphate:tRNA isopentenyltransferase
Legionella
<M><N><K><L><V><F><C><L><M><G><P><T><A><S><G><K><T><G><L><A><C><E><L><L><T><H><F><P><F><E><I><I><S><V><D><S><A><M><I><Y><R><D><M><N><I><G><T><A><K><P><S><I><H><E><L><Q><S><A><P><H><Y><L><I><D><I><K><D><P><V><E><S><Y><S><A><A><Q><F><C><T><D><A><L><S><L><C><A><A><I><I><K><R><G><N><I><P><L><L><V><G><G><T><M><M><Y><F><N><A...
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).<BOP>
Q5WTA1
Q8MY85
FGFR2_DUGJA
DjPTK1
Dugesia
<M><L><N><K><F><I><V><I><V><T><M><L><A><M><W><N><Y><A><Q><D><C><N><F><E><L><S><K><N><E><T><V><Q><F><T><S><F><L><P><L><I><L><N><C><A><S><I><S><K><F><D><T><D><L><C><E><T><I><N><D><E><R><P><Y><N><W><Y><F><Q><N><K><K><I><G><N><E><T><K><G><K><I><K><L><V><S><S><S><Q><Q><M><I><I><F><N><G><S><A><S><D><E><G><N><Y><M><C><E><T><I...
Receptor for basic fibroblast growth factor.<BOP>
Q8MY85
Q7N870
PANC_PHOLL
Pantoate-activating enzyme
Photorhabdus
<M><L><I><V><E><T><V><P><I><L><R><R><E><I><R><R><W><R><Q><E><G><K><R><I><A><L><V><P><T><M><G><N><L><H><D><G><H><M><T><L><V><D><T><A><K><G><Q><A><D><I><V><I><V><S><I><F><V><N><P><M><Q><F><N><R><P><D><D><L><A><K><Y><P><R><T><L><Q><E><D><C><E><K><L><H><Q><H><G><V><N><L><V><F><A><P><A><D><K><E><I><Y><P><D><G><M><E><H><Q><T...
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<BOP>
Q7N870
Q96A58
RERG_HUMAN
Ras-related and estrogen-regulated growth inhibitor
Homo
<M><A><K><S><A><E><V><K><L><A><I><F><G><R><A><G><V><G><K><S><A><L><V><V><R><F><L><T><K><R><F><I><W><E><Y><D><P><T><L><E><S><T><Y><R><H><Q><A><T><I><D><D><E><V><V><S><M><E><I><L><D><T><A><G><Q><E><D><T><I><Q><R><E><G><H><M><R><W><G><E><G><F><V><L><V><Y><D><I><T><D><R><G><S><F><E><E><V><L><P><L><K><N><I><L><D><E><I><K><K...
Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential.<BOP>
Q96A58
O48665
LGB5_PEA
Leghemoglobin Lb120-29
Pisum
<M><G><F><T><D><K><Q><E><A><L><V><N><S><S><W><E><L><F><K><Q><N><P><G><Y><S><V><L><F><Y><N><I><I><L><K><K><A><P><A><T><K><G><M><F><S><F><L><K><D><S><A><G><V><V><D><S><P><K><L><Q><A><H><A><E><K><V><F><G><M><V><H><D><S><A><V><Q><L><R><V><S><G><E><V><V><L><G><D><A><T><L><G><A><I><H><I><Q><K><G><V><V><D><S><H><F><V><V><V><K...
Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation.<BOP>
O48665
O45526
LSY27_CAEEL
Zinc finger protein lsy-27
Caenorhabditis
<M><T><S><I><H><S><P><V><T><R><K><E><D><T><E><L><K><R><P><D><L><R><G><K><F><V><C><S><S><C><S><Q><N><F><Q><H><S><A><S><L><N><R><H><R><Q><L><M><H><S><N><E><H><T><C><M><M><C><E><R><A><L><N><Q><K><E><T><I><R><E><H><M><R><N><E><H><N><L><A><Q><V><F><T><C><G><C><C><N><W><T><F><A><S><K><R><Q><L><T><E><H><T><K><C><I><Q><G><T><G...
Involved in regulating left/right asymmetric differentiation of the gustatory ASE neurons . Plays a role in modulating expression of LIM/homeobox protein lim-6 .<BOP>
O45526
Q331Q7
GERKI_STRSQ
dTDP-4-keto-6-deoxyallose reductase
Streptomyces
<M><T><A><D><R><W><A><G><R><T><V><L><V><T><G><A><L><G><F><I><G><S><H><F><V><R><Q><L><D><A><R><G><A><E><V><L><A><L><Y><R><T><E><R><P><E><I><Q><A><E><L><A><A><L><N><R><V><R><L><V><R><T><E><L><R><D><E><S><D><V><R><G><A><F><K><Y><L><A><P><S><I><D><T><V><V><H><C><A><A><M><D><G><N><A><Q><F><K><L><E><R><S><A><E><I><L><D><S><N...
Catalyzes the stereospecific reduction of the C-4 keto group of dTDP-4-dehydro-6-deoxy-D-allose, leading to dTDP-6-deoxy-D-allose, an intermediate in the biosynthesis of the mycinose moiety of dihydrochalcomycin (GERI-155) antibiotic. Cannot directly reduce dTDP-4-dehydro-6-deoxyglucose, and thus acts after the epimeri...
Q331Q7
Q94JG1
NRT23_ORYSJ
High-affinity nitrate transporter 2.3
Oryza sativa
<M><E><A><K><P><V><A><M><E><V><E><G><V><E><A><A><G><G><K><P><R><F><R><M><P><V><D><S><D><L><K><A><T><E><F><W><L><F><S><F><A><R><P><H><M><A><S><F><H><M><A><W><F><S><F><F><C><C><F><V><S><T><F><A><A><P><P><L><L><P><L><I><R><D><T><L><G><L><T><A><T><D><I><G><N><A><G><I><A><S><V><S><G><A><V><F><A><R><L><A><M><G><T><A><C><D><L...
Involved in nitrate transport, but does not seem to be able to mediate transport by its own. Acts as a dual component transporter with NAR2.1. Imports nitrate with high affinity when expressed with NAR2.1 in a heterologous system (Xenopus oocytes). Plays a key role in long-distance nitrate transport from root to shoot ...
Q94JG1
Q8DKQ1
HSLO_THEVB
Heat shock protein 33 homolog
Thermosynechococcus
<M><A><D><F><L><L><R><A><T><A><A><A><E><G><I><R><A><V><G><V><I><T><T><Q><L><T><D><E><A><R><K><R><H><Q><L><S><Y><V><A><T><A><A><L><G><R><T><M><A><A><G><L><I><L><A><S><S><F><K><Q><P><Q><A><R><V><N><V><R><I><Q><G><N><G><P><L><G><T><I><F><A><D><A><G><A><D><G><T><V><R><G><Y><V><Q><Y><P><S><V><E><L><P><P><N><A><K><G><K><L><D...
Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.<BOP>
Q8DKQ1
B3E7T5
RL3_TRIL1
50S ribosomal protein L3
Trichlorobacter
<M><N><K><G><I><I><G><K><K><L><G><M><T><Q><I><F><L><E><D><G><T><R><V><P><V><T><V><V><Q><A><G><P><C><V><V><L><Q><K><K><T><A><E><V><D><G><Y><S><A><V><Q><V><G><F><E><T><V><N><A><A><K><A><N><S><A><D><R><G><H><C><V><K><A><G><K><G><V><F><R><H><L><R><E><L><K><L><E><Q><E><A><E><L><N><I><G><D><E><L><T><V><Q><Q><F><E><P><G><D><L...
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP>
B3E7T5
A5VR14
RPOC_BRUO2
Transcriptase subunit beta'
Brucella
<M><N><Q><E><V><M><N><L><F><N><P><Q><A><P><A><Q><T><F><D><S><I><R><I><S><I><A><S><P><E><K><I><L><S><W><S><Y><G><E><I><K><K><P><E><T><I><N><Y><R><T><F><K><P><E><R><D><G><L><F><C><A><R><I><F><G><P><I><K><D><Y><E><C><L><C><G><K><Y><K><R><M><K><Y><K><G><I><I><C><E><K><C><G><V><E><V><T><L><S><R><V><R><R><E><R><M><G><H><I><E...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
A5VR14
C4XTD0
SYP_SOLM1
Prolyl-tRNA synthetase
Solidesulfovibrio
<M><R><L><S><R><Y><Y><A><P><T><L><K><E><T><P><A><E><A><E><V><I><S><H><K><L><L><L><R><A><G><M><I><R><K><L><T><A><G><I><Y><T><Y><L><P><L><G><L><K><A><L><N><N><V><A><K><I><V><R><E><E><M><D><R><A><G><A><L><E><I><L><M><P><A><V><Q><P><A><D><L><W><K><E><S><G><R><W><D><F><Y><G><R><E><L><L><R><F><V><D><R><H><D><R><E><S><C><L><G...
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two addit...
C4XTD0
P45186
MUKE_HAEIN
Chromosome partition protein MukE
Haemophilus
<M><T><D><I><Q><D><V><I><S><P><K><L><A><V><A><I><A><N><P><I><F><P><A><V><D><S><L><L><R><S><G><R><H><I><S><T><E><H><L><D><N><H><A><F><L><M><D><F><Q><N><E><L><D><G><F><Y><R><R><Y><N><V><E><L><I><R><A><P><E><G><F><F><Y><L><R><P><K><A><T><T><L><I><A><R><S><V><L><S><E><L><E><M><L><V><G><K><V><L><C><Y><L><Y><L><S><P><E><R><L...
Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.<BOP>
P45186
Q89AF2
FTSH_BUCBP
ATP-dependent zinc metalloprotease FtsH
Buchnera
<M><A><K><N><L><M><L><W><L><V><I><A><V><V><L><M><S><I><F><Q><N><F><S><A><N><N><I><N><N><R><K><I><D><Y><S><T><F><L><S><D><V><N><Q><D><Q><V><R><E><V><H><I><S><G><R><E><M><N><I><I><R><K><D><N><G><R><Y><I><T><Y><I><P><I><S><D><P><K><L><L><D><N><L><L><V><K><N><V><K><I><I><G><A><A><P><E><E><Q><S><F><F><T><A><I><F><I><S><W><F...
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.<BOP>
Q89AF2
Q760S6
RBS_NEODN
Ribulose bisphosphate carboxylase small subunit
Neoporphyra
<M><R><L><T><Q><G><T><F><S><F><L><P><D><L><T><D><E><Q><I><N><K><Q><L><T><Y><I><V><S><K><G><L><S><A><N><V><E><Y><T><D><D><P><H><P><R><N><S><Y><W><E><L><W><G><L><P><L><F><D><V><K><D><A><S><A><V><M><Y><E><I><S><S><C><R><K><A><K><P><N><Y><Y><V><K><V><N><A><F><D><N><T><R><G><I><E><S><C><V><M><S><F><I><V><N><R><P><A><N><E><P...
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Although the s...
Q760S6
Q59YD8
NOP16_CANAL
Nucleolar protein 16
Candida
<M><T><S><V><R><K><R><K><M><A><R><S><S><V><K><K><N><T><R><R><T><K><D><K><Q><R><N><I><N><I><H><S><N><P><I><I><E><A><N><W><D><K><S><L><T><L><K><Q><N><Y><K><R><L><G><L><R><A><K><L><G><R><S><A><G><G><D><E><R><K><V><E><S><L><S><E><L><Q><A><K><R><E><K><N><Q><K><N><Q><S><K><H><V><P><T><V><S><E><I><E><N><L><D><D><P><S><R><I><P...
Involved in the biogenesis of the 60S ribosomal subunit.<BOP>
Q59YD8
L7WRQ4
NOTA_ASPVE
Notoamide biosynthesis cluster protein A'
Aspergillus subgen. Nidulantes
<M><T><N><T><N><R><R><T><I><T><V><Y><G><A><T><G><A><Q><G><G><P><V><V><R><S><L><L><K><N><N><A><F><K><V><R><A><I><T><R><K><P><E><S><E><A><A><K><A><L><A><D><L><G><A><E><I><V><Q><G><D><G><W><K><K><E><Q><M><V><A><A><F><S><G><S><W><A><A><F><V><N><T><N><S><D><D><P><C><F><W><D><A><N><H><P><T><E><F><D><L><G><K><I><I><I><D><G><I...
NmrA-like family domain-containing oxidoreductase; part of the gene cluster that mediates the biosynthesis of notoamide, a fungal indole alkaloid that belongs to a family of natural products containing a characteristic bicyclo[2.2.2]diazaoctane core . The first step of notoamide biosynthesis involves coupling of L-prol...
L7WRQ4
B2FQ14
RF1_STRMK
Peptide chain release factor 1
Stenotrophomonas maltophilia group
<M><T><P><T><L><R><R><K><L><E><A><L><A><E><R><R><E><E><L><E><R><L><L><A><E><P><D><V><V><A><D><N><T><R><F><R><D><L><S><R><E><F><A><Q><L><E><P><I><A><I><A><L><A><D><E><S><R><A><K><A><D><L><A><A><A><E><G><M><R><A><D><P><D><L><R><E><L><A><D><E><E><I><A><A><A><Q><A><R><L><L><E><L><E><Q><E><L><A><L><L><L><V><P><R><D><P><R><D...
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.<BOP>
B2FQ14
P0C8J5
SL2C2_VIPAA
Snaclec factor X-activator 2 light chain 2
Vipera
<A><F><C><C><P><S><G><W><S><A><Y><D><Q><N><C><Y>
Regulatory subunit of the blood coagulation factor X-activating enzyme. Activates coagulation factor X (F10) in a calcium-dependent manner by cleaving the Arg-Ile bond at position 234. Weakly hydrolyzes insulin B chain, fibrinogen and some components of the extracellular matrix in vitro, but does not activate prothromb...
P0C8J5
P21909
EDD_ZYMMO
6-phosphogluconate dehydratase
Zymomonas
<M><T><D><L><H><S><T><V><E><K><V><T><A><R><V><I><E><R><S><R><E><T><R><K><A><Y><L><D><L><I><Q><Y><E><R><E><K><G><V><D><R><P><N><L><S><C><S><N><L><A><H><G><F><A><A><M><N><G><D><K><P><A><L><R><D><F><N><R><M><N><I><G><V><V><T><S><Y><N><D><M><L><S><A><H><E><P><Y><Y><R><Y><P><E><Q><M><K><V><F><A><R><E><V><G><A><T><V><Q><V><A...
Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate.<BOP>
P21909
A0T0K0
RPOA_PHATC
Plastid-encoded RNA polymerase subunit alpha
Phaeodactylum
<M><N><N><I><S><I><K><C><L><K><S><E><K><I><Q><S><G><A><C><H><G><Q><F><L><I><N><S><L><N><P><G><Q><G><I><T><I><G><N><Q><L><R><R><V><L><L><G><D><L><G><G><V><A><I><S><A><V><R><I><A><G><I><T><H><E><F><S><T><I><P><G><V><R><E><D><I><L><E><I><L><L><N><L><K><G><I><I><C><T><S><Q><I><Q><D><T><Q><F><G><H><L><K><V><Q><G><P><S><V><V...
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.<BOP>
A0T0K0
A2Q7V4
MEP_ASPNC
Fungalysin mep
Aspergillus subgen. Circumdati
<M><H><G><L><R><L><V><C><S><I><G><T><L><P><L><V><I><L><A><Y><P><A><A><S><L><H><T><T><S><A><A><V><D><L><D><S><L><R><L><T><S><N><S><E><Y><V><N><S><V><H><V><D><T><N><R><S><V><A><V><S><A><E><E><H><Y><T><D><T><A><A><R><L><V><Q><N><I><V><P><G><A><S><F><R><L><I><D><D><H><F><V><G><D><N><G><V><A><H><V><Y><F><R><Q><T><L><H><G><I...
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.<BOP>
A2Q7V4
Q98QL0
RNR_MYCPU
VacB protein homolog
Mycoplasmopsis
<M><K><N><L><V><L><Q><N><L><K><S><N><K><A><Y><S><F><L><E><I><A><R><I><N><K><I><N><P><N><F><N><S><Q><L><S><K><A><L><F><S><L><L><D><Q><G><L><I><V><K><N><N><D><G><N><F><I><K><V><N><E><I><K><K><I><Q><G><I><F><K><Q><S><N><R><N><F><A><F><I><E><T><A><D><E><Q><S><Y><F><V><A><K><A><H><F><N><G><A><I><N><S><F><E><V><E><A><I><V><Y...
3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.<BOP>
Q98QL0
A9HRJ3
YQGF_GLUDA
Putative pre-16S rRNA nuclease
Gluconacetobacter
<M><P><L><F><N><M><H><Q><I><R><G><Q><L><G><R><D><Q><R><L><L><G><L><D><P><G><Q><K><T><I><G><L><A><L><S><D><V><S><L><M><L><A><S><P><Y><G><A><L><R><R><G><K><L><S><V><V><A><A><E><I><R><R><I><A><A><R><E><G><V><G><G><L><V><S><G><L><P><L><S><M><D><G><S><F><G><P><A><A><Q><A><A><R><D><W><M><I><S><L><S><E><Q><V><G><L><P><A><A><M...
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP>
A9HRJ3
Q5WEP5
HEM3_ALKCK
Pre-uroporphyrinogen synthase
Alkalihalobacillus
<M><R><K><I><V><I><G><T><R><R><S><K><L><A><L><T><Q><T><N><W><V><I><D><Q><L><K><Q><L><G><V><P><Y><E><F><E><V><K><E><I><V><T><K><G><D><R><I><L><D><V><T><L><S><K><V><G><G><K><G><L><F><V><K><E><I><E><A><A><L><R><S><G><E><I><D><V><A><V><H><S><M><K><D><V><P><S><E><L><L><E><E><F><T><L><A><A><I><T><E><R><E><D><P><R><D><V><L><V...
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.<BOP>
Q5WEP5
E3QDQ4
MAP21_COLGM
Peptidase M
Colletotrichum graminicola species complex
<M><G><S><K><T><P><E><E><Q><I><P><G><G><N><G><G><P><P><S><T><G><P><S><S><S><G><G><E><P><R><G><T><H><L><S><R><D><G><D><G><S><L><G><D><H><G><D><D><D><D><A><D><E><D><D><V><S><S><R><P><L><R><A><D><V><E><E><K><K><K><K><K><R><P><K><K><K><K><K><P><A><A><A><K><E><Q><S><S><P><P><R><V><P><L><S><D><L><F><P><L><G><E><Y><P><A><G><E...
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).<BOP>
E3QDQ4
A4XHM5
RISB_CALS8
6,7-dimethyl-8-ribityllumazine synthase
Caldicellulosiruptor
<M><R><T><F><E><G><S><F><C><G><K><D><L><K><L><A><I><V><V><S><R><F><N><S><F><I><T><D><E><L><L><K><G><C><L><D><G><L><S><R><H><D><V><D><S><E><N><I><D><V><Y><Y><V><P><G><A><F><E><I><P><L><V><A><K><K><L><A><K><S><K><K><Y><N><A><I><I><A><L><G><A><V><I><R><G><S><T><P><H><F><E><Y><V><S><A><E><V><S><K><G><I><A><N><V><S><L><E><Q...
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<BOP>
A4XHM5
Q65Q27
RHAT_MANSM
L-rhamnose-H(+) transport protein
Basfia
<M><G><G><S><I><L><L><G><I><F><W><H><F><V><G><A><T><S><A><A><C><F><Y><A><P><M><K><K><V><T><N><W><S><W><E><T><M><W><A><I><A><G><I><F><S><W><I><L><L><P><W><G><I><S><Y><W><L><L><P><D><F><G><S><Y><Y><S><F><F><G><S><D><I><L><L><P><V><F><L><F><G><A><M><W><G><I><G><N><I><G><Y><G><L><T><M><R><Y><L><G><M><S><M><G><I><G><I><A><I...
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).<BOP>
Q65Q27
Q7N486
TRPB_PHOLL
Tryptophan synthase beta chain
Photorhabdus
<M><S><K><L><N><P><Y><F><G><D><F><G><G><Q><F><V><P><Q><I><L><I><P><A><L><E><Q><L><E><A><A><F><I><A><A><Q><Q><D><P><E><F><Q><Q><E><F><Q><D><L><L><K><N><Y><A><G><R><P><T><A><L><T><L><C><R><N><L><T><K><G><T><K><T><R><L><Y><L><K><R><E><D><L><L><H><G><G><A><H><K><T><N><Q><V><L><G><Q><A><L><L><A><K><R><M><G><K><N><E><I><I><A...
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP>
Q7N486
Q8U0K5
IF1A_PYRFU
Translation initiation factor 1A
Pyrococcus
<M><L><M><P><K><K><E><R><K><V><E><G><E><E><V><I><R><V><P><L><P><E><G><N><Q><L><F><G><V><V><E><Q><A><L><G><A><G><W><M><D><V><R><C><E><D><G><K><V><R><R><C><R><I><P><G><R><L><R><R><R><V><W><I><K><V><G><D><L><V><I><V><E><P><W><P><V><Q><S><D><K><R><G><D><I><V><Y><R><Y><T><Q><T><Q><V><E><W><L><L><R><K><G><K><I><S><Q><E><F><L...
Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.<BOP>
Q8U0K5
B8E2A8
RS20_DICTD
30S ribosomal protein S20
Dictyoglomus
<M><A><N><T><K><S><A><I><K><R><I><K><I><S><E><R><N><R><I><R><N><R><V><R><L><G><K><I><K><F><Y><T><K><Q><F><L><K><F><L><N><E><N><N><I><E><E><A><K><K><I><L><P><E><V><I><S><A><I><D><K><A><A><Q><K><G><T><L><H><K><N><T><A><A><R><K><K><S><K><L><M><K><L><L><N><Q><K><L><S><A><N><L><S><S>
Binds directly to 16S ribosomal RNA.<BOP>
B8E2A8
A1USL0
RS7_BARBK
30S ribosomal protein S7
Bartonella
<M><S><R><R><H><R><A><E><K><R><E><I><N><P><D><P><K><F><G><D><V><V><I><T><K><F><M><N><A><I><M><F><D><G><K><K><S><V><A><E><R><I><V><Y><G><A><L><D><V><V><E><G><K><V><K><T><D><P><V><A><L><F><H><Q><A><L><E><N><V><A><P><H><I><E><V><R><S><R><R><V><G><G><A><T><Y><Q><V><P><V><D><V><R><P><D><R><R><Q><A><L><A><I><R><W><L><I><K><A...
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.<BOP>
A1USL0
Q6D4A2
RUVB_PECAS
Holliday junction ATP-dependent DNA helicase RuvB
Pectobacterium
<M><I><E><A><D><R><L><I><S><A><D><A><V><P><E><E><E><F><L><D><R><A><M><R><P><K><L><L><K><E><Y><V><G><Q><P><Q><V><R><E><Q><M><E><I><F><I><Q><A><A><R><K><R><G><D><A><L><D><H><L><L><I><F><G><P><P><G><L><G><K><T><T><L><A><N><I><V><A><N><E><M><G><V><N><M><R><T><T><S><G><P><V><L><E><K><A><G><D><L><A><A><L><L><T><N><L><E><P><H...
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.<BOP>
Q6D4A2
P56823
HCYG_HELPO
Hemocyanin, beta-C chain unit G
Helix
<D><I><H><T><T><A><V><A><G><V><G><V><R><K><D><V><T><R><L><T><V><S><E><T><E><N><L><R><E><A><L><R><R><I><K><A><D><N><G><S><D><G><F><Q><S><I><A><S><F><H><G><S><P><P><G><C><E><H><E><N><H><S><V><A><C><C><I><H><G><M><A><N><F><P><Q><W><H><R><L><Y><V><K><Q><W><E><D><A><L><T><A><Q><G><A><K><I><G><I><P><Y><W><D><W><T><T><A><F><T...
Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods.<BOP>
P56823
P28495
CAPZA_YEAST
F-actin-capping protein subunit alpha
Saccharomyces
<M><S><S><S><K><F><E><E><V><I><N><K><I><I><N><D><S><P><P><G><E><L><R><E><V><Y><D><D><L><I><K><I><T><S><E><N><S><K><N><T><I><L><D><A><I><E><N><Y><N><V><Q><N><C><I><P><I><E><V><N><G><N><S><V><I><I><S><K><Y><N><K><E><G><A><K><F><F><D><P><V><N><S><V><I><F><S><V><N><H><L><E><R><K><G><L><D><I><E><P><Y><E><F><T><H><A><K><I><E...
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.<BOP>
P28495
B7NDQ3
AROE_ECOLU
Shikimate dehydrogenase (NADP(+))
Escherichia
<M><E><T><Y><A><V><F><G><N><P><I><A><H><S><K><S><P><F><I><H><Q><Q><F><A><Q><Q><L><N><I><E><H><P><Y><G><R><V><L><A><P><I><N><D><F><I><N><T><L><N><A><F><F><S><A><G><G><K><G><A><N><V><T><V><P><F><K><E><E><A><F><A><R><A><D><E><L><T><E><R><A><A><L><A><G><A><V><N><T><L><K><R><L><E><D><G><R><L><L><G><D><N><T><D><G><I><G><L><L...
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).<BOP>
B7NDQ3
A6TVI5
HPRK_ALKMQ
HPr(Ser) kinase/phosphorylase
Alkaliphilus
<M><K><S><I><T><V><E><K><L><M><K><D><L><N><M><E><E><L><N><S><I><E><A><T><A><L><L><I><S><T><T><D><L><N><R><P><G><M><Q><L><A><G><F><F><D><Y><F><A><Y><E><R><I><Q><I><I><G><K><V><E><H><R><Y><L><E><T><L><D><T><K><T><R><K><E><R><L><D><R><M><M><S><Y><D><I><P><C><L><I><I><S><R><G><L><E><V><P><E><E><L><L><C><T><A><N><K><Y><Q><R...
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphor...
A6TVI5
Q2W2J1
RL3_MAGSA
50S ribosomal protein L3
Magnetospirillum
<M><R><S><G><L><I><A><Q><K><V><G><M><T><R><I><F><T><E><D><G><T><H><V><P><V><T><V><L><K><V><D><T><C><Q><V><V><S><T><R><S><V><E><K><D><G><Y><V><A><V><Q><L><G><A><G><T><A><K><V><K><N><V><S><K><P><A><R><A><N><F><A><K><A><K><V><E><P><K><K><K><L><V><E><F><R><V><A><P><E><N><L><L><E><V><G><T><E><L><S><A><A><H><F><I><P><G><Q><Y...
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.<BOP>
Q2W2J1
P59048
PDRG1_MOUSE
p53 and DNA damage-regulated protein 1
Mus
<M><L><S><P><E><A><E><R><V><L><R><Y><L><V><E><V><E><E><L><A><E><A><V><L><S><D><K><R><Q><I><V><D><L><D><T><K><R><N><Q><N><R><E><G><L><R><A><L><Q><K><D><L><S><V><S><E><D><V><M><V><C><F><G><N><M><F><I><K><M><P><H><P><K><T><K><E><M><I><Q><K><D><Q><E><H><L><D><K><E><I><E><R><L><R><S><Q><L><K><V><K><V><N><R><L><F><E><A><Q><G...
May play a role in chaperone-mediated protein folding.<BOP>
P59048
Q57TL5
SYI_SALCH
Isoleucyl-tRNA synthetase
Salmonella
<M><S><D><Y><K><S><T><L><N><L><P><E><T><G><F><P><M><R><G><D><L><A><K><R><E><P><G><M><L><A><R><W><T><D><D><D><L><Y><G><I><I><R><A><A><K><K><G><K><K><T><F><I><L><H><D><G><P><P><Y><A><N><G><S><I><H><I><G><H><S><V><N><K><I><L><K><D><I><I><V><K><S><K><G><L><S><G><F><D><S><P><Y><V><P><G><W><D><C><H><G><L><P><I><E><L><K><V><E...
Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrol...
Q57TL5
Q60336
ARTE_METJA
Probable archaeosortase E
Methanocaldococcus
<M><G><S><L><L><M><E><R><N><F><M><V><E><D><T><F><T><N><G><K><L><S><K><K><E><K><I><L><F><L><I><K><F><Y><I><I><F><L><V><V><F><F><I><L><S><Y><F><G><K><Y><L><I><G><I><V><T><Y><L><S><Y><I><F><T><K><I><I><I><S><D><A><R><L><A><D><N><F><I><Y><L><P><N><N><T><V><E><V><V><E><E><C><T><G><S><F><L><I><A><G><L><L><A><L><I><I><V><Y><S...
Transpeptidase that recognizes and modifies its substrate by proteolytic cleavage of a sorting signal. Following cleavage, a covalent intermediate is formed via a thioester bond between the archaeosortase and its substrate, which is then transferred and covalently attached to the cell membrane.<BOP>
Q60336
Q8DT23
METK_STRMU
Methionine adenosyltransferase
Streptococcus
<M><S><E><R><K><L><F><T><S><E><S><V><S><E><G><H><P><D><K><I><A><D><Q><I><S><D><A><I><L><D><A><V><L><V><Q><D><P><D><A><H><V><A><A><E><T><A><V><Y><T><G><S><V><H><V><F><G><E><I><S><T><T><A><Y><V><D><I><N><R><V><V><R><D><T><I><A><E><I><G><Y><T><D><T><A><Y><G><F><S><A><E><T><V><G><V><H><P><S><L><V><E><Q><S><P><D><I><A><Q><G...
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.<BOP>
Q8DT23
Q28571
THB_SHEEP
Nuclear receptor subfamily 1 group A member 2
Ovis
<M><T><P><N><S><M><T><E><N><G><L><P><A><W><D><K><P><K><P><C><P><D><G><E><P><E><W><K><L><V><G><M><S><E><A><C><L><H><R><K><S><H><P><E><R><R><G><P><L><K><H><E><Q><S><P><L><I><Q><A><S><W><T><S><S><I><F><H><L><D><H><D><D><V><S><D><Q><S><A><P><S><A><Q><A><F><Q><T><E><E><K><K><C><K><G><Y><I><P><S><Y><L><D><K><D><E><L><C><V><V...
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.<BOP>
Q28571
Q9U1H0
CIC_DROME
Protein fettucine
Sophophora
<M><N><A><F><Q><D><F><E><L><G><A><K><L><Y><L><Q><C><L><L><S><L><S><S><S><R><S><A><T><P><S><Y><T><S><P><V><N><H><A><G><A><S><P><L><N><A><I><A><H><S><P><V><N><V><S><A><T><H><R><Q><N><F><F><T><P><I><A><N><Q><S><Q><Q><Q><Q><Q><Q><Q><P><V><A><V><P><L><D><S><K><W><K><T><T><P><S><P><V><L><Y><N><A><N><N><N><S><S><N><N><N><T><S...
Transcriptional repressor required for the specification of numerous cell types during embryonic development. Required for terminal patterning of early embryos. May associate with gro to repress tll and hkb, restricting their expression to embryonic terminal poles where they initiate correct development of head and tai...
Q9U1H0
C4LDB2
TIG_TOLAT
PPIase
Tolumonas
<M><Q><V><S><V><E><T><T><Q><G><L><E><R><R><L><T><I><T><V><P><A><D><K><I><E><K><E><Y><N><S><R><L><N><Q><V><A><K><T><R><R><I><D><G><F><R><P><G><K><A><P><K><A><L><I><Q><K><M><Y><G><E><S><I><V><A><D><V><A><D><A><V><M><Q><R><H><F><V><E><A><L><V><A><E><K><L><N><P><V><G><A><P><T><L><E><P><N><Q><L><V><P><G><S><D><F><T><F><T><V...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
C4LDB2
Q7N8V7
RSMA_PHOLL
S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase
Photorhabdus
<M><N><N><R><V><H><Q><G><H><F><A><R><K><R><F><G><Q><N><F><L><T><D><Q><F><V><I><D><S><I><A><A><A><I><N><P><Q><P><G><Q><A><V><L><E><I><G><P><G><L><G><A><L><T><E><P><V><G><E><R><M><D><K><M><T><V><V><E><L><D><R><D><L><A><A><R><L><Q><V><H><P><Q><L><K><D><K><L><T><I><I><Q><Q><D><A><M><T><V><N><F><G><E><L><S><Q><Q><R><G><K><P...
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.<BOP>
Q7N8V7
B1XIE7
NDK_SYNP2
Nucleoside-2-P kinase
unclassified Synechococcus
<M><E><R><T><F><V><M><V><K><P><D><G><V><Q><R><G><L><V><G><D><V><I><R><R><F><E><A><K><G><F><K><L><V><G><L><K><L><V><S><V><S><R><E><L><A><E><Q><H><Y><G><V><H><R><E><R><P><F><F><G><S><L><V><E><F><I><I><S><V><P><V><V><A><M><V><W><E><G><K><G><A><I><A><A><A><R><K><I><I><G><A><T><N><P><L><E><A><E><P><G><T><I><R><G><D><F><G><V...
(Microbial infection) Catalyzes the phosphorylation of dZDP to dZTP, when the bacterium is infected by a phage that produces the substrate for the synthesis of dZTP (2- amino-2'-deoxyadenosine 5'-triphosphate), which is then used by the phage as a DNA polymerase substrate.<BOP>
B1XIE7
Q6G401
LIPA_BARHE
Sulfur insertion protein LipA
Bartonella
<M><V><T><V><V><D><R><V><T><D><R><R><L><R><H><P><E><K><A><H><R><P><D><T><S><V><Q><K><K><P><D><W><I><R><V><K><A><P><T><S><Q><V><Y><K><E><T><H><G><I><V><R><A><H><K><L><V><T><V><C><E><E><A><G><C><P><N><I><G><E><C><W><S><Q><R><H><A><S><F><M><I><L><G><E><I><C><T><R><A><C><A><F><C><N><V><A><T><G><I><P><F><A><V><D><E><N><E><P...
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.<BOP>
Q6G401
Q9X7R6
RNH_STRCO
Ribonuclease HI
Streptomyces albidoflavus group
<M><R><E><R><A><V><A><A><C><D><G><A><S><K><G><N><P><G><P><A><G><W><A><W><V><V><A><D><A><S><E><N><P><V><R><W><E><A><G><P><L><G><K><A><T><N><N><I><A><E><L><T><A><L><E><R><L><L><A><S><T><D><P><D><V><P><L><E><V><R><M><D><S><Q><Y><A><M><K><A><V><T><T><W><L><P><G><W><K><R><N><G><W><K><T><A><A><G><K><P><V><A><N><R><E><L><V><V...
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.<BOP>
Q9X7R6
A6WPJ2
PEPE_SHEB8
Dipeptidase E
Shewanella
<M><T><I><N><A><L><L><L><S><S><S><R><V><G><D><T><P><Y><L><A><H><A><I><P><F><I><K><P><L><T><T><N><A><Q><K><W><I><F><I><P><Y><A><G><V><S><M><S><Y><D><N><Y><L><A><S><V><V><T><G><L><S><E><L><E><L><D><I><S><G><I><H><Q><H><P><D><P><Q><Q><A><I><K><D><A><D><G><I><L><I><G><G><G><N><T><F><H><L><L><H><Q><L><Y><R><Y><D><L><V><T><L...
Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.<BOP>
A6WPJ2
Q5YP21
LEXA1_NOCFA
LexA repressor 1
Nocardia
<M><T><D><Y><D><F><E><H><L><D><T><S><A><L><P><V><R><Q><R><R><I><L><E><V><I><R><D><W><V><V><E><H><G><Y><A><P><S><T><R><Q><I><G><A><A><V><G><L><R><S><M><S><S><V><A><R><H><L><R><S><L><E><E><R><G><F><L><R><R><G><E><G><V><A><R><P><I><D><V><R><L><F><L><H><G><T><A><A><A><A><P><S><E><D><A><V><T><V><P><V><V><G><D><I><A><A><G><A...
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair...
Q5YP21
Q5LSS5
RL13_RUEPO
50S ribosomal protein L13
Ruegeria
<M><K><T><F><S><A><T><P><A><D><I><D><K><K><W><I><L><I><D><A><E><G><V><V><L><G><R><L><A><S><I><V><A><M><R><L><R><G><K><H><K><A><S><F><T><P><H><M><D><M><G><D><N><V><I><V><I><N><A><D><K><V><Q><I><T><G><K><K><R><E><E><H><F><Y><W><H><T><G><H><P><G><G><I><K><S><R><T><K><Q><Q><I><L><E><G><A><H><P><E><R><V><V><Y><Q><A><V><K><R...
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.<BOP>
Q5LSS5
Q03WG9
RS14_LEUMM
30S ribosomal protein S14
Leuconostoc
<M><A><K><K><S><K><I><A><K><A><Q><K><R><E><A><L><V><A><K><Y><A><D><K><R><A><A><L><K><A><A><G><D><Y><I><G><L><A><A><L><P><K><D><S><S><P><V><R><V><H><N><R><D><W><I><D><G><R><P><H><A><Y><M><R><E><F><G><M><S><R><L><N><F><R><Q><L><A><H><K><G><Q><I><P><G><V><R><K><A><S><W>
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.<BOP>
Q03WG9
Q9N0T1
STC1_BOVIN
Stanniocalcin-1
Bos
<M><L><Q><N><S><A><V><L><L><V><L><V><I><S><A><S><A><T><H><E><A><E><Q><N><D><S><V><S><L><R><K><S><R><V><A><A><Q><N><S><A><E><V><I><R><C><L><N><S><A><L><Q><V><G><C><G><A><F><A><C><L><E><N><S><T><C><D><T><D><G><M><Y><D><I><C><K><S><F><L><Y><S><A><A><K><F><D><T><Q><G><K><A><F><V><K><E><S><L><K><C><I><A><N><G><V><T><S><K><V...
Stimulates renal phosphate reabsorption, and could therefore prevent hypercalcemia.<BOP>
Q9N0T1
Q65S74
SOTB_MANSM
Probable sugar efflux transporter
Basfia
<M><L><N><R><K><L><V><N><R><V><E><Y><F><R><V><I><V><M><A><F><A><A><F><V><F><N><T><T><E><F><V><P><V><A><L><L><S><D><I><A><D><S><F><Q><M><P><V><S><N><T><G><L><M><I><T><I><Y><A><W><I><V><S><L><C><S><L><P><C><M><L><M><T><A><R><L><E><R><R><R><L><L><I><S><L><F><I><L><F><I><A><S><H><I><L><S><A><F><A><W><N><Y><E><V><L><L><I><A...
Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.<BOP>
Q65S74
Q7UDU1
DNAJ_SHIFL
Chaperone protein DnaJ
Shigella
<M><A><K><Q><D><Y><Y><E><I><L><G><V><S><K><T><A><E><E><R><E><I><R><K><A><Y><K><R><L><A><M><K><Y><H><P><D><R><N><Q><G><D><K><E><A><E><A><K><F><K><E><I><K><E><A><Y><E><V><L><T><D><S><Q><K><R><A><A><Y><D><Q><Y><G><H><A><A><F><E><Q><G><G><M><G><G><G><G><F><G><G><G><A><D><F><S><D><I><F><G><D><V><F><G><D><I><F><G><G><G><R><G...
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bou...
Q7UDU1
A5VQP4
ISPDF_BRUO2
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Brucella
<M><Q><A><Q><S><L><A><E><V><T><V><I><S><K><A><A><A><V><I><V><A><A><G><R><G><E><R><A><G><Q><S><A><E><G><P><K><Q><Y><R><L><I><G><A><E><A><V><L><A><R><T><L><R><A><F><T><D><C><P><L><I><G><T><I><A><V><V><I><H><P><D><D><H><A><L><Y><R><R><A><V><P><E><K><H><E><N><V><I><L><V><T><G><G><P><T><R><Q><E><S><T><R><L><G><L><L><A><L><K...
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a ...
A5VQP4
P07262
DHE4_YEAST
NADP-dependent glutamate dehydrogenase 1
Saccharomyces
<M><S><E><P><E><F><Q><Q><A><Y><E><E><V><V><S><S><L><E><D><S><T><L><F><E><Q><H><P><E><Y><R><K><V><L><P><I><V><S><V><P><E><R><I><I><Q><F><R><V><T><W><E><N><D><K><G><E><Q><E><V><A><Q><G><Y><R><V><Q><Y><N><S><A><K><G><P><Y><K><G><G><L><R><F><H><P><S><V><N><L><S><I><L><K><F><L><G><F><E><Q><I><F><K><N><S><L><T><G><L><D><M><G...
Catalyzes the incorporation of an ammonium ion into alpha-ketoglutarate to form L-glutamate, the major route of assimilation of ammonia into an organic form in yeast.<BOP>
P07262
B8AW64
NAP1B_ORYSI
Nucleosome assembly protein 1-like 2
Oryza sativa
<M><S><D><G><K><D><S><L><D><L><S><G><L><G><A><A><V><P><N><A><K><E><L><S><A><E><D><K><A><N><L><V><E><S><I><K><N><T><L><Q><G><L><A><A><R><H><T><D><V><L><E><S><L><E><P><K><V><R><K><R><V><E><V><L><R><E><I><Q><S><Q><H><D><D><L><E><A><K><F><F><E><E><R><A><A><L><E><A><K><Y><Q><K><M><Y><E><P><L><Y><S><K><R><Y><E><I><V><N><G><V...
May modulate chromatin structure by regulation of nucleosome assembly/disassembly.<BOP>
B8AW64
A6V720
TIG_PSEA7
PPIase
Pseudomonas
<M><Q><V><S><V><E><S><T><S><A><L><E><R><R><M><T><V><G><V><P><A><E><R><I><E><T><E><V><N><K><R><L><Q><Q><T><A><R><R><A><K><I><P><G><F><R><P><G><K><V><P><M><S><V><I><R><Q><R><Y><E><A><S><A><R><Q><E><A><M><G><D><L><I><Q><E><T><F><Y><E><A><V><V><E><Q><K><L><N><P><A><G><S><P><S><V><E><P><K><S><F><E><K><G><K><D><L><E><Y><I><A...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
A6V720
A9IN82
MUTL_BART1
DNA mismatch repair protein MutL
Bartonella
<M><I><I><R><H><L><S><E><N><I><I><N><Q><I><A><A><G><E><V><I><E><R><P><A><N><V><V><K><E><L><V><E><N><A><I><D><A><G><A><T><R><I><E><I><I><T><A><N><G><G><K><N><F><I><K><V><S><D><N><G><C><G><I><P><A><D><Q><L><T><L><A><V><S><R><H><C><T><S><K><I><T><D><D><V><H><N><I><C><F><L><G><F><R><G><E><A><L><P><S><I><G><S><V><A><K><L><K...
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part ...
A9IN82
A1WIF0
PSD_VEREI
Phosphatidylserine decarboxylase beta chain
Verminephrobacter
<M><P><D><R><L><A><V><L><A><Q><Y><A><L><P><K><R><A><L><T><T><W><A><G><K><W><A><S><A><R><L><G><G><L><T><T><A><L><I><R><R><F><V><A><R><Y><D><V><N><M><A><E><A><A><N><P><D><M><A><G><Y><A><S><F><N><D><F><F><T><R><A><L><Q><P><G><A><R><P><L><A><R><A><D><L><I><C><P><V><D><G><A><I><S><Q><F><G><R><I><G><K><D><R><I><F><Q><A><K><G...
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).<BOP>
A1WIF0
F4K2F0
EML3_ARATH
Protein EMSY-LIKE 3
Arabidopsis
<M><D><Y><R><P><S><D><S><S><G><T><D><D><D><L><P><P><S><H><Q><G><R><Y><Q><R><N><A><R><P><T><G><N><G><R><P><S><V><L><N><S><A><P><L><S><R><V><H><N><E><M><E><T><Q><I><H><L><I><E><Q><E><A><Y><S><S><I><L><R><A><F><K><A><Q><S><D><A><I><T><W><E><K><E><S><L><I><T><E><L><R><K><E><L><R><V><S><D><E><E><H><R><E><L><L><S><R><V><N><A...
Probably involved in the regulation of chromatin states (Probable). Contributes to basal immunity .<BOP>
F4K2F0
P22636
PCYB_SPHSK
4,5-PCD
Sphingobium
<M><A><R><V><T><T><G><I><T><S><S><H><I><P><A><L><G><A><A><I><Q><T><G><T><S><D><N><D><Y><W><G><P><V><F><K><G><Y><Q><P><I><R><D><W><I><K><Q><P><G><N><M><P><D><V><V><I><L><V><Y><N><D><H><A><S><A><F><D><M><N><I><I><P><T><F><A><I><G><C><A><E><T><F><K><P><A><D><E><G><W><G><P><R><P><V><P><D><V><K><G><H><P><D><L><A><W><H><I><A...
Responsible for the aromatic ring fission of protocatechuate.<BOP>
P22636
Q38XF6
ACCD_LATSS
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta
Latilactobacillus
<M><Q><L><F><N><A><V><R><N><I><G><K><A><H><L><K><Y><N><Q><E><A><R><Q><K><V><P><D><G><L><W><V><A><C><P><K><C><Q><Q><S><I><Y><H><K><D><L><G><Y><Y><R><T><C><P><V><C><Q><Y><G><F><R><T><R><A><K><V><R><L><D><W><L><V><D><S><F><E><P><A><G><D><L><A><Q><T><P><N><P><L><H><F><P><K><Y><P><Q><K><L><R><K><A><Q><Q><I><T><G><L><E><D><S...
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.<BOP>
Q38XF6
Q9SA47
MYB58_ARATH
Myb-related protein 58
Arabidopsis
<M><G><K><G><R><A><P><C><C><D><K><T><K><V><K><R><G><P><W><S><H><D><E><D><L><K><L><I><S><F><I><H><K><N><G><H><E><N><W><R><S><L><P><K><Q><A><G><L><L><R><C><G><K><S><C><R><L><R><W><I><N><Y><L><R><P><D><V><K><R><G><N><F><S><A><E><E><E><D><T><I><I><K><L><H><Q><S><F><G><N><K><W><S><K><I><A><S><K><L><P><G><R><T><D><N><E><I><K...
Transcriptional activator that binds DNA to the AC cis-elements 5'-ACCTACC-3', 5'-ACCAACC-3' and 5'-ACCTAAC-3' of promoters and specifically activates lignin biosynthetic genes during secondary wall formation mediated by SND1.<BOP>
Q9SA47
Q13BT8
ISPE_RHOPS
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase
Rhodopseudomonas
<M><T><A><L><S><E><Q><A><R><A><K><V><N><L><T><L><R><V><V><G><R><R><V><D><G><Y><H><D><L><E><S><V><V><A><F><A><D><C><A><D><R><L><T><L><H><P><G><A><E><L><S><L><V><M><S><G><P><G><A><Q><D><C><G><D><T><S><D><N><L><V><L><K><A><T><R><L><L><A><E><R><V><P><N><L><R><T><G><G><F><V><L><D><K><H><L><P><V><A><A><G><I><G><G><G><S><A><D...
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.<BOP>
Q13BT8