accession stringlengths 6 10 | name stringlengths 6 11 | Full Name stringlengths 1 147 ⌀ | taxon stringlengths 3 46 ⌀ | sequence stringlengths 48 8.26k | function stringlengths 11 5.52k | AlphaFoldDB stringlengths 6 10 |
|---|---|---|---|---|---|---|
P55470 | Y4GN_SINFN | Uncharacterized protein y4gN | Sinorhizobium | <M><D><Q><T><L><S><R><R><L><F><L><W><H><N><P><Q><T><D><N><Q><C><R><N><E><R><H><M><I><H><T><S><K><I><Y><R><E><I><N><R><I><G><V><Q><I><K><G><L><P><D><Y><W><M><G><Q><A><R><R><I><S><Y><D><R><V><G><S><A><G><N><T><I><T><E><G><R><K><P><V><S><A><D><M><A><I><L><L><I><Y><Q><P><R><G><L><L><E><S><L><F><L><Q><L><E><H><L><L><S><K><G... | Could have an enzymatic function.<BOP> | P55470 |
Q5WZ61 | TRMB_LEGPL | tRNA(m7G46)-methyltransferase | Legionella | <M><Q><R><K><I><K><S><Y><V><L><R><A><G><R><I><S><N><R><Q><Q><Q><G><L><D><L><W><L><E><D><Y><E><L><K><F><D><S><P><S><P><W><N><F><A><K><E><F><G><R><H><D><A><D><T><I><V><E><I><G><F><G><M><G><T><S><L><F><A><M><A><M><N><N><P><Q><C><N><Y><L><G><I><E><V><H><K><A><G><V><G><S><L><V><A><D><L><H><E><Y><Q><I><S><N><V><R><V><V><A><H... | Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP> | Q5WZ61 |
C1A8T0 | UVRC_GEMAT | Excinuclease ABC subunit C | Gemmatimonas | <M><P><V><A><Q><K><L><P><H><L><P><E><S><P><G><V><Y><L><W><K><D><V><E><G><Q><V><L><Y><V><G><K><A><K><R><L><R><S><R><V><R><S><Y><W><A><Q><E><H><E><S><S><P><K><T><R><A><M><V><R><K><V><R><D><L><E><T><I><V><V><P><S><E><A><H><A><L><I><L><E><A><T><L><I><K><E><Y><H><P><R><F><N><I><A><L><R><D><D><K><S><Y><P><Y><I><R><V><T><V><N... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | C1A8T0 |
A3M4W0 | TRMA_ACIBT | tmRNA (uracil(341)-C(5))-methyltransferase | Acinetobacter calcoaceticus/baumannii complex | <M><T><S><S><Y><R><Q><Q><L><Q><A><K><I><D><R><I><T><T><Q><F><S><E><F><T><P><P><T><L><E><V><F><E><S><P><E><Q><H><F><R><M><R><A><E><F><R><I><W><H><T><E><N><D><M><F><Y><A><M><F><E><R><N><D><D><G><K><Q><K><T><V><V><R><I><D><E><F><P><I><A><D><K><S><I><N><D><L><M><P><L><L><L><A><E><L><K><A><N><S><L><L><S><Q><R><L><F><E><V><D... | Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).<BOP> | A3M4W0 |
O67108 | TOP4A_AQUAE | DNA gyrase subunit A | Aquifex | <M><E><N><R><E><N><L><V><E><I><P><I><E><E><E><V><K><Q><A><Y><I><D><Y><A><M><S><V><I><V><G><R><A><I><P><D><V><R><D><G><L><K><P><V><Q><R><R><I><L><Y><S><M><Y><E><M><G><L><L><P><D><K><P><F><K><K><S><A><R><I><V><G><E><T><L><G><K><Y><H><P><H><G><D><Q><A><V><Y><E><A><L><V><R><M><A><Q><D><F><T><M><R><Y><P><L><I><I><G><Q><G><N... | A type II topoisomerase. Despite its similarity to DNA gyrase, this enzyme is not able to supercoil DNA, and instead acts like topoisomerase IV. Relaxes both positively and negatively supercoiled DNA in an ATP-dependent fashion, decatenates interlocked circles. This the first bacteria shown to not contain DNA gyrase, a... | O67108 |
Q7XKF4 | YSL13_ORYSJ | Protein YELLOW STRIPE LIKE 13 | Oryza sativa | <M><A><T><V><P><T><P><S><E><A><H><G><G><A><T><P><T><A><A><D><V><E><M><V><E><A><S><E><L><R><R><R><G><K><P><S><G><D><R><A><T><G><P><S><R><D><G><A><A><A><A><A><E><E><A><A><A><P><S><V><E><R><V><F><A><D><R><P><V><P><S><W><R><E><Q><L><T><V><R><A><F><V><V><S><F><F><L><V><I><M><F><S><V><I><V><M><K><L><N><L><T><T><G><I><I><P><S... | May be involved in the transport of nicotianamine-chelated metals.<BOP> | Q7XKF4 |
P08562 | TBB_TRYCR | Beta-tubulin | Schizotrypanum | <M><R><E><I><V><C><V><Q><A><G><Q><C><G><N><Q><I><G><S><K><F><W><E><V><I><S><D><E><H><G><V><D><P><T><G><T><Y><Q><G><D><S><D><L><Q><L><E><R><I><N><V><Y><F><D><E><A><T><G><G><R><Y><V><P><R><A><V><L><I><D><L><E><P><G><T><M><D><S><V><R><A><G><P><Y><G><Q><I><F><R><P><D><N><F><I><F><G><Q><S><G><A><G><N><N><W><A><K><G><H><Y><T... | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-... | P08562 |
Q8U192 | THIE_PYRFU | Thiamine-phosphate pyrophosphorylase | Pyrococcus | <M><N><L><R><N><K><L><K><L><Y><V><I><T><D><R><R><L><K><P><E><V><E><S><V><R><E><A><L><E><G><G><A><T><A><I><Q><M><R><I><K><N><A><P><T><R><E><M><Y><E><I><G><K><T><L><R><Q><L><T><R><E><Y><D><A><L><F><F><V><D><D><R><V><D><V><A><L><A><V><D><A><D><G><V><Q><L><G><P><E><D><M><P><I><E><V><A><K><E><I><A><P><N><L><I><I><G><A><S><V... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | Q8U192 |
C3PBW1 | THIE_BACAA | Thiamine-phosphate pyrophosphorylase | Bacillus cereus group | <M><S><R><I><S><K><A><E><M><S><K><L><L><S><V><Y><F><I><M><G><S><N><N><C><T><K><D><P><L><Q><V><L><R><E><A><L><E><G><F><I><T><I><F><Q><F><R><E><K><G><E><G><A><L><T><G><E><E><R><I><C><F><A><K><E><L><Q><A><I><C><K><E><Y><G><V><P><F><I><V><N><D><D><V><E><L><A><L><E><L><D><A><D><G><V><H><V><G><Q><D><D><E><G><I><T><S><V><R><E... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | C3PBW1 |
P16559 | TCMN_STRGA | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | Streptomyces | <M><A><A><R><T><D><N><S><I><V><V><N><A><P><F><E><L><V><W><D><V><T><N><D><I><E><A><W><P><E><L><F><S><E><Y><A><E><A><E><I><L><R><Q><D><G><D><G><F><D><F><R><L><K><T><R><P><D><A><N><G><R><V><W><E><W><V><S><H><R><V><P><D><K><G><S><R><T><V><R><A><H><R><V><E><T><G><P><F><A><Y><M><N><L><H><W><T><Y><R><A><V><A><G><G><T><E><M><R... | The N-terminal domain enhances the formation of an early, partially cyclized intermediate, while the C-terminal domain catalyzes the 3-O-methylation of one or more later intermediates in the biosynthetic pathway. Catalyzes the methylation of tetracenomycin D3 (Tcm D3) to yield Tcm B3. Catalyzes as well the following si... | P16559 |
P0C7B1 | VM3BG_BOTAL | Snake venom metalloproteinase | Bothrops | <S><I><S><A><C><N><G><L><K><G><H><F><L><I><E><P><L><K><L><S><D><S><E><K><T><D><L><L><N><R><S><H><D><N><A><Q><L><S><P><I><N><L><V><V><A><V><I><M><A><H><E><M><G><H><G><M><V><L><P><G><T><K> | Snake venom Zinc metalloproteinase that inhibits ADP-induced platelet aggregation and inhibits the alpha-5/beta-1 (ITGA5/ITGB1) integrin, a fibronectin receptor. Has caseinolytic activity. Induces the detachment of cells that are bound to fibronectin.<BOP> | P0C7B1 |
Q14593 | ZN273_HUMAN | Zinc finger protein HZF9 | Homo | <M><S><S><A><P><R><G><P><P><S><V><A><P><L><P><A><G><I><G><R><S><T><A><K><T><P><G><L><P><G><S><L><E><M><G><P><L><T><F><R><D><V><A><I><E><F><S><L><E><E><W><Q><C><L><D><T><S><Q><Q><N><L><Y><R><N><V><M><L><D><N><Y><R><N><L><V><F><L><G><I><A><V><S><K><P><D><L><I><T><C><L><E><Q><G><K><E><P><C><N><M><K><R><H><A><M><V><A><K><P... | May be involved in transcriptional regulation.<BOP> | Q14593 |
B4R1P9 | TOTX_DROSI | Protein Turandot X | Sophophora | <M><G><L><H><I><G><S><L><L><I><C><V><F><L><G><I><L><P><F><A><T><A><N><T><N><R><S><G><Y><E><E><Q><R><N><Y><L><L><N><I><F><H><N><P><L><V><N><D><S><I><K><E><K><N><I><P><E><L><I><A><F><Y><Q><R><Y><P><T><D><V><P><L><S><D><A><D><R><Q><Q><F><E><R><F><I><H><D><Y><R><E><Y><R><E><V><L><V><D><G><V><P><P><Q><G><G><S><F><G><N><I><F... | A humoral factor that may play a role in stress tolerance.<BOP> | B4R1P9 |
Q7M9S1 | TRPB1_WOLSU | Tryptophan synthase beta chain 1 | Wolinella | <M><M><H><K><P><Y><L><K><S><F><P><N><K><E><G><Y><F><G><K><Y><G><G><A><Y><L><P><P><L><L><I><E><H><F><K><E><I><G><E><A><Y><L><K><I><S><Q><S><F><D><F><I><Q><E><L><K><S><I><R><K><H><Y><Q><G><R><P><T><P><L><Y><Y><A><R><R><L><S><Q><K><A><G><G><A><A><I><Y><L><K><R><E><D><L><N><H><T><G><A><H><K><L><N><H><C><M><A><E><A><L><L><A... | The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP> | Q7M9S1 |
A9AGE2 | UBIA_BURM1 | 4-HB polyprenyltransferase | Burkholderia cepacia complex | <M><L><A><R><F><P><L><Y><L><R><L><V><R><M><D><K><P><I><G><S><L><L><L><L><W><P><T><L><N><A><L><W><I><A><S><D><G><H><P><R><W><P><L><I><V><I><F><A><L><G><T><L><L><M><R><S><A><G><C><A><M><N><D><Y><A><D><R><D><F><D><R><H><V><K><R><T><A><D><R><P><L><T><S><G><K><I><R><A><W><E><A><V><A><I><A><V><G><L><S><F><V><A><F><L><L><I><L... | Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-... | A9AGE2 |
Q8ECV0 | TRPB_SHEON | Tryptophan synthase beta chain | Shewanella | <M><S><Q><L><K><L><N><P><Y><F><G><E><Y><G><G><M><Y><V><P><Q><I><L><V><P><A><L><K><Q><L><E><S><A><F><V><E><A><Q><T><D><E><S><F><Q><A><E><F><T><D><L><L><K><N><Y><A><G><R><P><T><A><L><T><L><T><R><N><L><S><P><N><P><M><V><K><I><Y><L><K><R><E><D><L><L><H><G><G><A><H><K><T><N><Q><V><L><G><Q><A><L><L><A><K><R><M><G><K><K><E><I... | The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP> | Q8ECV0 |
P47750 | TSHR_MOUSE | Thyroid-stimulating hormone receptor | Mus | <M><R><P><G><S><L><L><L><L><V><L><L><L><A><L><S><R><S><L><R><G><K><E><C><A><S><P><P><C><E><C><H><Q><E><D><D><F><R><V><T><C><K><E><L><H><R><I><P><S><L><P><P><S><T><Q><T><L><K><L><I><E><T><H><L><K><T><I><P><S><L><A><F><S><S><L><P><N><I><S><R><I><Y><L><S><I><D><A><T><L><Q><R><L><E><P><H><S><F><Y><N><L><S><K><M><T><H><I><E... | Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.<BOP... | P47750 |
Q06J27 | YCF3_BIGNA | Photosystem I assembly protein Ycf3 | Bigelowiella | <M><P><R><S><Q><K><N><D><N><F><I><D><K><T><F><T><V><V><A><D><I><L><L><K><V><L><P><T><S><I><D><E><K><R><A><F><T><Y><Y><R><N><G><M><S><A><Q><S><E><G><E><Y><A><E><A><L><Q><N><Y><Y><Q><A><L><R><Y><E><I><D><A><Y><D><R><S><Y><M><L><Y><N><I><G><L><I><H><S><S><N><G><Q><Q><S><K><A><L><E><Y><Y><Y><Q><A><L><D><R><N><P><R><L><S><Q... | Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits.<BOP> | Q06J27 |
Q8PEW6 | TTCA_XANAC | tRNA 2-thiocytidine biosynthesis protein TtcA | Xanthomonas | <M><T><A><V><L><P><L><P><Q><P><L><A><D><P><A><P><R><D><P><R><Q><R><L><Q><R><E><Q><L><R><L><G><K><R><L><Q><R><Q><V><G><Q><A><I><A><D><F><G><M><I><A><P><G><D><K><I><M><V><C><L><S><G><G><K><D><S><Y><T><L><L><D><M><L><L><Q><L><Q><R><K><A><P><V><P><F><S><L><V><A><V><N><L><D><Q><K><Q><P><D><F><P><A><H><V><L><P><A><Y><L><R><G... | Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.<BOP> | Q8PEW6 |
Q4JG17 | VASAL_PENVA | Vasa-like protein | Penaeus | <M><S><D><D><W><D><E><T><D><A><A><P><A><S><D><W><N><I><E><S><F><G><L><P><T><S><F><G><S><T><K><K><T><C><N><T><G><N><A><F><N><D><G><E><G><G><F><D><E><G><S><Q><S><N><F><D><D><P><F><R><S><G><G><G><G><F><G><G><R><G><R><G><G><P><R><A><C><F><K><C><G><D><E><G><H><M><A><R><D><C><P><S><A><S><D><S><R><G><N><R><T><N><N><R><R><Q><D... | Involved in translational control mechanisms operating in early stages of oogenesis. Required maternally in many stages of oogenesis, including cystocyte differentiation, oocyte differentiation, and specification of anterior-posterior polarity in the developing cysts. Essential for the formation and/or structural integ... | Q4JG17 |
B2SDE3 | UVRC_FRATM | Excinuclease ABC subunit C | Francisella | <M><I><V><D><N><S><K><D><F><D><L><K><S><F><L><A><N><L><T><T><H><S><G><V><Y><R><M><L><D><K><H><G><E><I><I><Y><V><G><K><A><K><N><L><K><N><R><V><N><S><Y><F><S><K><G><A><K><D><S><K><T><L><M><M><V><E><Q><I><A><R><I><E><I><T><I><T><P><S><D><Y><E><A><Y><L><L><E><N><N><L><I><K><Q><H><R><P><K><Y><N><I><L><F><K><D><D><K><S><Y><P... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | B2SDE3 |
B5YKY0 | Y1069_THEYD | Nucleoid-associated protein THEYE_A1069 | Thermodesulfovibrio | <M><S><K><K><M><F><G><E><I><M><R><Q><A><Q><K><I><Q><E><E><I><Q><K><K><Q><E><E><V><K><K><M><T><V><E><A><T><S><G><G><G><M><V><T><V><Q><A><N><G><A><G><E><I><V><S><I><K><I><D><R><E><V><V><N><P><D><D><I><E><M><L><E><D><L><V><L><A><A><V><N><E><A><I><K><R><A><H><E><L><A><Q><S><E><M><A><K><V><S><M><P><F><N><L><P><G><M><P><D><L... | Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP> | B5YKY0 |
Q9VMR8 | TOTM_DROME | Protein Turandot M | Sophophora | <M><N><P><T><I><Y><L><S><C><L><M><V><F><S><V><F><L><L><G><K><V><N><A><E><N><E><D><E><F><V><T><E><K><Q><R><L><F><S><V><Y><G><D><S><S><V><D><E><A><T><K><Y><R><N><I><D><S><L><V><T><F><Y><D><K><Y><F><T><R><L><Q><L><K><P><D><L><N><T><R><A><H><D><L><L><R><R><Y><K><E><E><N><A><R><V><V><L><V><D><G><T><P><A><Q><G><G><F><W><L><P... | A humoral factor that may play a role in stress tolerance. Requires Mekk1 expression in the fat body to regulate response to septic injury and consequent immune response.<BOP> | Q9VMR8 |
P37806 | UNC87_CAEEL | Uncoordinated protein 87 | Caenorhabditis | <M><L><S><F><N><N><T><T><S><A><S><S><F><Q><S><A><S><S><R><Y><L><M><S><S><S><S><S><I><G><P><P><Q><Q><Q><S><A><K><L><F><P><E><H><F><Y><P><S><G><L><S><P><R><Q><S><E><A><L><E><R><L><R><P><N><T><A><S><R><E><R><N><I><P><I><Q><F><T><G><K><N><P><T><T><N><S><A><L><E><E><Y><K><P><V><P><H><V><Q><V><T><S><P><K><S><S><I><V><P><N><F... | Acts as a negative regulator of myosin-dependent contractility of smooth muscle-like cells in the somatic gonad.<BOP> | P37806 |
C3N1X1 | Y365_SULIA | Putative antitoxin M1627_0365 | Sulfolobus | <M><A><K><T><I><T><I><S><E><E><A><Y><K><L><L><L><K><E><K><R><D><G><E><S><F><S><D><V><I><V><R><L><I><K><G><N><R><R><E><V><M><D><Y><A><G><I><W><S><D><M><N><D><E><E><S><N><K><L><F><K><D><L><E><K><M><W><E><R><W><N><V><N><A> | Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.<BOP> | C3N1X1 |
E9L011 | UGTB1_STABO | UDP-glucosyltransferase B1 | Starmerella | <M><A><I><E><K><P><V><I><V><A><C><A><C><P><L><A><G><H><V><G><P><V><L><S><L><V><R><G><L><L><N><R><G><Y><E><V><T><F><V><T><G><N><A><F><K><E><K><V><I><E><A><G><C><T><F><V><P><L><Q><G><R><A><D><Y><H><E><Y><N><L><P><E><I><A><P><G><L><L><T><I><P><P><G><L><E><Q><T><G><Y><S><M><N><E><I><F><V><K><A><I><P><E><Q><Y><D><A><L><Q><T... | Catalyzes the second glycosylation step of sophorolipid biosynthesis, the further glucosylation of the previoulsy formed glucolipid to give rise to an acidic sophorolipid.<BOP> | E9L011 |
Q8QHK3 | VSP1_CROAT | Catroxase I | Crotalus | <M><V><L><I><R><V><L><A><N><L><L><I><L><Q><L><S><Y><A><Q><K><S><S><E><P><I><I><G><G><D><E><C><N><R><N><E><H><R><F><L><A><L><V><S><S><D><G><N><Q><C><G><G><T><L><I><N><E><E><W><V><L><T><A><A><H><C><E><G><N><K><M><K><I><H><L><G><V><H><S><K><K><V><P><N><K><D><K><Q><T><R><V><A><K><E><K><F><F><C><V><S><S><K><N><Y><T><F><W><D... | Snake venom serine protease that may act in the hemostasis system of the prey.<BOP> | Q8QHK3 |
P32819 | YAMY_BACAD | Uncharacterized 39.9 kDa protein in amylase 3'region | Bacillus | <M><D><P><I><A><L><D><E><R><I><G><T><L><D><Y><L><R><G><F><A><L><L><G><I><I><L><V><N><I><L><G><L><L><T><V><K><T><P><A><L><H><S><V><D><A><V><Y><Q><R><F><L><Y><F><F><V><E><A><R><F><Y><P><I><F><S><F><L><F><G><V><G><F><Y><L><F><I><A><R><A><N><T><R><G><E><N><G><A><I><L><F><L><R><R><I><L><V><L><F><I><F><G><F><I><H><F><L><F><Q... | Involved in transport.<BOP> | P32819 |
Q3ANX8 | TAL_CHLCH | Probable transaldolase | Chlorobium | <M><Q><F><F><I><D><T><A><N><L><D><E><I><R><A><A><A><E><L><G><V><L><D><G><V><T><T><N><P><S><L><I><A><K><V><A><G><S><S><K><P><F><T><W><Q><A><F><K><D><H><I><A><A><I><C><E><I><V><D><G><P><V><S><A><E><V><T><A><L><D><A><N><G><M><I><D><Q><G><E><E><L><A><D><I><D><G><K><V><V><I><K><C><P><V><T><L><E><G><L><K><A><I><S><Y><F><D><E... | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP> | Q3ANX8 |
A9LYA2 | YCF3_ACOAM | Photosystem I assembly protein Ycf3 | Acorus | <M><P><R><S><R><I><N><A><N><F><I><D><K><T><S><T><I><V><A><N><I><L><L><R><I><I><P><T><T><S><G><E><K><E><A><F><T><Y><Y><R><D><G><M><S><A><Q><S><E><G><N><Y><A><E><A><L><Q><N><Y><Y><E><A><T><R><P><E><I><D><P><Y><D><R><S><Y><I><L><Y><N><I><G><L><I><H><T><S><N><G><E><H><T><K><A><L><E><Y><Y><F><R><A><L><E><R><N><P><F><L><P><Q... | Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits.<BOP> | A9LYA2 |
A7Z4T7 | TRUB_BACVZ | tRNA-uridine isomerase | Bacillus amyloliquefaciens group | <M><V><N><G><V><L><L><L><H><K><P><V><G><M><T><S><H><D><C><V><M><K><I><R><K><L><L><K><T><K><K><V><G><H><T><G><T><L><D><P><E><V><S><G><V><L><P><I><C><V><G><R><A><T><K><I><V><E><Y><V><T><D><K><S><K><T><Y><D><A><E><I><T><L><G><F><S><T><S><T><E><D><Q><T><G><E><T><V><S><V><K><P><V><K><E><P><L><K><E><A><D><I><K><A><V><L><D><E... | Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP> | A7Z4T7 |
Q07QT9 | UREG_RHOP5 | Urease accessory protein UreG | Rhodopseudomonas | <M><A><R><Y><N><G><P><L><R><V><G><I><G><G><P><V><G><S><G><K><T><A><L><M><D><L><L><C><K><E><L><R><E><R><Y><Q><I><A><A><I><T><N><D><I><Y><T><K><W><D><A><E><F><L><V><R><S><G><S><L><T><P><D><R><I><V><G><V><E><T><G><G><C><P><H><T><A><I><R><E><D><A><S><M><N><L><A><A><V><A><D><M><R><A><K><F><P><D><L><D><L><V><L><I><E><S><G><G... | Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP> | Q07QT9 |
P86176 | TIGIT_MOUSE | V-set and transmembrane domain-containing protein 3 | Mus | <M><H><G><W><L><L><L><V><W><V><Q><G><L><I><Q><A><A><F><L><A><T><A><I><G><A><T><A><G><T><I><D><T><K><R><N><I><S><A><E><E><G><G><S><V><I><L><Q><C><H><F><S><S><D><T><A><E><V><T><Q><V><D><W><K><Q><Q><D><Q><L><L><A><I><Y><S><V><D><L><G><W><H><V><A><S><V><F><S><D><R><V><V><P><G><P><S><L><G><L><T><F><Q><S><L><T><M><N><D><T><G... | Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.<BOP> | P86176 |
Q7ZUK7 | WAC_DANRE | WW domain-containing adapter protein with coiled-coil | Danio | <M><V><M><Y><A><R><K><Q><P><R><L><G><D><G><C><T><D><R><R><D><S><Q><P><Y><Q><T><L><K><Y><S><S><K><S><H><P><D><H><R><H><E><K><M><R><D><S><N><D><A><T><P><P><C><K><M><L><R><R><S><D><S><P><D><N><K><H><M><D><N><T><G><H><G><R><A><K><A><I><H><P><H><R><G><R><E><R><E><G><G><T><S><I><S><P><Q><E><N><S><H><N><H><S><S><L><H><S><S><N... | Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Positive regulator of amino acid starvation-induced autophagy. Positively regulates MTOR activity. May negatively regulate the ubiquitin proteasome pathway.<BOP> | Q7ZUK7 |
Q929F3 | YHAM_LISIN | 3'-5' exoribonuclease YhaM | Listeria | <M><E><K><R><L><L><D><Y><E><V><G><E><T><V><E><L><F><L><L><I><K><S><S><V><K><G><T><A><S><N><G><K><P><F><L><S><L><V><L><Q><D><K><S><G><E><L><E><A><K><L><W><D><V><K><E><S><D><E><I><N><Y><G><V><Q><Q><I><V><H><L><M><G><D><I><Q><N><Y><R><G><R><K><Q><L><K><I><R><Q><I><R><Q><A><S><P><L><D><G><V><S><A><S><E><F><M><E><T><A><P><I... | Shows a 3'-5' exoribonuclease activity.<BOP> | Q929F3 |
Q822W3 | TRPB2_CHLCV | Tryptophan synthase beta chain 2 | Chlamydia | <M><K><H><P><Y><P><F><G><G><Q><F><M><P><E><I><L><M><A><P><V><Q><D><L><S><N><S><W><K><S><L><Q><N><H><S><D><F><K><N><E><L><D><S><V><L><K><N><Y><A><G><R><P><T><P><L><T><E><I><K><N><F><A><K><A><I><H><G><P><R><I><F><L><K><R><E><D><L><L><H><T><G><A><H><K><I><N><N><A><L><G><Q><C><L><L><A><K><H><L><G><K><T><R><I><I><A><E><T><G... | The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP> | Q822W3 |
Q91241 | THAA_PAROL | Nuclear receptor subfamily 1 group A member 1-A | Paralichthys | <M><E><P><M><S><N><K><Q><D><S><N><S><S><E><G><D><E><K><G><W><P><D><V><P><K><R><K><R><K><N><S><Q><C><S><M><K><S><M><S><A><L><S><V><S><V><P><G><Y><I><P><S><Y><L><E><K><D><E><P><C><V><V><C><G><D><K><A><T><G><Y><H><Y><R><C><I><T><C><E><G><C><K><G><F><F><R><R><T><I><Q><K><N><L><H><P><S><Y><S><C><K><Y><E><G><C><C><I><I><D><K... | High affinity receptor for triiodothyronine.<BOP> | Q91241 |
A0PVP6 | Y4430_MYCUA | Putative S-adenosyl-L-methionine-dependent methyltransferase MUL_4430 | Mycobacterium | <M><A><R><T><E><G><D><S><W><D><L><A><N><S><V><G><A><T><A><T><M><V><A><A><A><R><A><A><A><T><R><R><S><R><P><I><I><A><D><P><F><A><E><P><L><V><R><A><V><G><L><D><L><F><T><R><A><A><S><G><E><V><D><L><D><E><V><A><A><G><L><G><F><V><R><M><V><D><T><F><A><A><R><A><L><F><F><D><K><F><F><A><D><A><I><A><A><G><L><R><Q><V><V><I><V><A><S... | Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.<BOP> | A0PVP6 |
D1GY43 | UBA5_DROAN | Ubiquitin-like modifier-activating enzyme 5 | Sophophora | <M><S><H><A><I><D><E><L><Q><A><I><I><A><E><L><K><V><E><L><E><E><Q><K><T><S><N><R><Q><A><R><S><R><I><D><R><M><S><A><E><V><V><D><S><N><P><Y><S><R><L><M><A><L><Q><R><M><N><I><V><K><E><Y><E><R><I><R><D><K><A><V><A><V><V><G><V><G><G><V><G><S><V><T><A><D><M><L><T><R><C><G><I><G><K><L><I><L><F><D><Y><D><K><V><E><L><A><N><M><N... | E1-like enzyme which activates UFM1.<BOP> | D1GY43 |
P19123 | TNNC1_MOUSE | Troponin C, slow skeletal and cardiac muscles | Mus | <M><D><D><I><Y><K><A><A><V><E><Q><L><T><E><E><Q><K><N><E><F><K><A><A><F><D><I><F><V><L><G><A><E><D><G><C><I><S><T><K><E><L><G><K><V><M><R><M><L><G><Q><N><P><T><P><E><E><L><Q><E><M><I><D><E><V><D><E><D><G><S><G><T><V><D><F><D><E><F><L><V><M><M><V><R><C><M><K><D><D><S><K><G><K><S><E><E><E><L><S><D><L><F><R><M><F><D><K><N... | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.<BOP> | P19123 |
A4QJQ8 | TI214_AETGR | Translocon at the inner envelope membrane of chloroplasts 214 | Aethionema | <M><M><V><F><Q><S><F><I><L><G><N><L><V><S><L><C><M><K><I><I><N><S><V><V><V><V><G><L><Y><Y><G><F><L><T><T><F><S><I><G><P><S><Y><L><F><L><L><R><A><R><V><M><D><E><G><E><E><G><T><E><K><K><V><S><A><T><T><G><F><I><A><G><Q><L><M><M><F><I><S><I><Y><Y><A><P><L><H><L><A><L><G><R><P><H><T><I><T><V><L><A><L><P><Y><L><L><F><H><F><F... | Involved in protein precursor import into chloroplasts. May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.<BOP> | A4QJQ8 |
Q5V4R4 | TOP6A_HALMA | Type II DNA topoisomerase VI subunit A | Haloarcula | <M><S><T><D><S><D><T><T><P><D><T><E><E><A><R><E><Q><L><I><D><L><A><A><D><F><Y><D><Q><F><A><D><G><E><V><P><T><M><T><I><P><T><R><T><K><S><N><I><V><F><D><E><D><E><Q><V><W><V><Y><G><D><R><N><S><T><R><S><A><K><T><I><S><G><A><E><K><I><L><K><A><V><Y><T><I><D><F><L><S><Q><Q><L><E><E><D><R><S><S><T><L><R><E><L><Y><Y><L><S><E><S... | Relaxes both positive and negative superturns and exhibits a strong decatenase activity.<BOP> | Q5V4R4 |
A9VUC4 | TGL_BACMK | Transglutaminase | Bacillus cereus group | <M><I><V><I><G><R><S><I><V><H><P><Y><I><T><N><E><Y><E><P><F><A><A><E><K><Q><Q><I><L><S><I><M><A><G><N><Q><E><V><Y><S><F><R><T><A><D><E><L><S><F><D><L><N><L><R><V><N><I><I><T><S><A><L><E><L><F><Q><S><G><F><Q><F><R><T><F><Q><Q><S><F><C><N><P><Q><F><W><E><R><T><S><L><G><G><F><Q><L><L><P><N><I><A><P><S><I><A><I><Q><D><I><F... | Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links.<BOP> | A9VUC4 |
Q8Y4D5 | Y2514_LISMO | DegV domain-containing protein lmo2514 | Listeria | <M><N><E><K><I><A><V><V><T><D><S><T><T><Y><L><P><D><E><V><K><E><Q><L><R><I><N><V><V><P><L><S><V><I><I><D><G><K><S><Y><R><E><G><E><E><L><S><A><T><D><F><Y><R><K><V><K><E><A><E><N><F><P><T><S><S><Q><P><A><P><G><E><F><I><H><L><F><E><N><L><K><E><Q><G><F><D><T><V><I><S><I><H><L><S><S><G><I><S><G><T><F><Q><N><A><A><S><A><G><E... | May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.<BOP> | Q8Y4D5 |
A6WZV4 | TYSY_BRUA4 | Thymidylate synthase | Brucella | <M><R><T><Y><L><D><L><L><Q><H><V><L><D><N><G><T><D><R><G><D><R><T><G><T><G><T><R><S><V><F><G><Y><Q><M><R><F><N><L><E><E><G><F><P><V><L><T><T><K><K><L><H><L><R><S><I><I><H><E><L><L><W><F><L><K><G><D><T><N><I><A><Y><L><K><E><N><G><V><S><I><W><D><E><W><A><D><K><N><G><D><L><G><P><V><Y><G><Y><Q><W><R><S><W><P><A><P><D><G><R... | Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell... | A6WZV4 |
Q829Y6 | UVRB_STRAW | Excinuclease ABC subunit B | Streptomyces | <M><R><P><V><S><K><I><E><R><T><V><A><P><F><E><V><V><S><P><Y><Q><P><S><G><D><Q><P><A><A><I><A><E><L><D><R><R><I><R><A><G><E><K><D><V><V><L><L><G><A><T><G><T><G><K><S><A><T><T><A><W><M><I><E><K><L><Q><R><P><T><L><V><M><A><P><N><K><T><L><A><A><Q><L><A><N><E><F><R><E><L><L><P><N><N><A><V><E><Y><F><V><S><Y><Y><D><Y><Y><Q><P... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi... | Q829Y6 |
B3LGB9 | TRM82_YEAS1 | Transfer RNA methyltransferase 82 | Saccharomyces | <M><S><V><I><H><P><L><Q><N><L><L><T><S><R><D><G><S><L><V><F><A><I><I><K><N><C><I><L><S><F><K><Y><Q><S><P><N><H><W><E><F><A><G><K><W><S><D><D><F><D><K><I><Q><E><S><R><N><T><T><A><K><E><Q><Q><G><Q><S><S><E><N><E><N><E><N><K><K><L><K><S><N><K><G><D><S><I><K><R><T><A><A><K><V><P><S><P><G><L><G><A><P><P><I><Y><S><Y><I><R><N... | Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA, a modification required to maintain stability of tRNAs; its absence resulting in tRNA decay. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.<BOP> | B3LGB9 |
Q11DE1 | TAL_CHESB | Probable transaldolase | unclassified Chelativorans | <M><K><F><F><V><D><T><A><D><V><N><E><I><R><E><L><S><E><T><G><L><L><D><G><V><T><T><N><P><S><L><I><M><K><S><G><R><P><I><L><E><V><T><R><E><I><C><E><I><V><D><G><P><V><S><A><E><V><T><A><V><D><F><K><E><M><M><R><E><A><D><I><L><S><K><I><A><D><N><I><A><I><K><V><P><L><T><M><D><G><L><K><A><C><K><A><L><T><S><S><G><R><M><V><N><V><T... | Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP> | Q11DE1 |
Q01QT2 | TILS_SOLUE | tRNA(Ile)-lysidine synthetase | Candidatus Solibacter | <M><F><A><S><G><A><R><V><A><V><G><V><S><G><G><A><D><S><V><C><L><L><H><A><L><V><E><L><G><G><L><K><L><S><V><L><H><V><D><H><G><L><R><G><A><E><S><R><A><D><A><E><F><V><G><E><L><A><A><R><M><G><L><P><F><C><L><R><E><V><T><L><G><P><G><N><V><E><Q><E><G><R><R><A><R><L><R><F><F><H><E><Q><L><A><A><G><N><C><D><R><V><A><L><G><H><T><R... | Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP> | Q01QT2 |
Q97QD1 | Y1288_STRPN | UPF0122 protein SP_1288 | Streptococcus | <M><E><I><E><K><T><N><R><M><N><A><L><F><E><F><Y><A><A><L><L><T><D><K><Q><M><N><Y><I><E><L><Y><Y><A><D><D><Y><S><L><A><E><I><A><E><E><F><G><V><S><R><Q><A><V><Y><D><N><I><K><R><T><E><K><I><L><E><D><Y><E><M><K><L><H><M><Y><S><D><Y><I><V><R><S><Q><I><F><D><Q><I><L><E><R><Y><P><K><D><D><F><L><Q><E><Q><I><E><I><L><T><S><I><D... | Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.<BOP> | Q97QD1 |
Q316N1 | YQGF_OLEA2 | Putative pre-16S rRNA nuclease | Oleidesulfovibrio | <M><K><Y><L><G><I><D><Y><G><T><R><R><T><G><I><A><V><T><D><G><A><G><M><M><A><F><P><R><R><T><I><V><M><S><T><R><D><A><F><F><A><E><L><L><S><V><V><E><E><E><R><P><A><G><V><V><V><G><L><P><L><L><A><G><G><E><E><T><L><I><T><R><Q><V><R><N><F><V><A><R><L><R><R><R><S><S><L><P><V><Y><L><V><A><E><E><L><S><S><F><E><A><G><E><D><L><R><E... | Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP> | Q316N1 |
B9MKC1 | TRUA_CALBD | tRNA-uridine isomerase I | Caldicellulosiruptor | <M><R><N><I><L><L><T><I><E><Y><D><G><T><G><Y><F><G><W><Q><K><Q><P><N><K><K><T><I><Q><G><T><I><E><E><A><I><K><K><L><T><G><E><E><V><N><L><I><G><S><G><R><T><D><R><G><V><H><A><L><N><Q><K><A><N><F><K><T><S><S><K><I><P><T><D><K><F><P><L><A><L><N><S><V><L><P><G><D><I><S><I><K><D><A><V><E><A><P><L><D><F><S><A><R><Y><S><A><R><Q... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | B9MKC1 |
Q1MBA9 | UBIG_RHIL3 | 3-demethylubiquinone 3-O-methyltransferase | Rhizobium | <M><T><E><G><A><K><S><T><I><D><Q><G><E><V><D><R><F><S><A><M><A><A><E><W><W><S><P><T><G><K><F><K><P><L><H><K><F><N><P><V><R><L><A><Y><I><R><D><K><A><C><E><N><F><S><R><D><P><K><S><A><R><P><L><E><G><L><R><V><L><D><I><G><C><G><G><G><L><L><S><E><P><V><A><R><M><G><A><S><V><V><G><A><D><P><S><E><K><N><I><G><I><A><S><T><H><A><K... | O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP> | Q1MBA9 |
Q18HD7 | TRM56_HALWD | tRNA ribose 2'-O-methyltransferase aTrm56 | Haloquadratum | <M><K><R><S><C><E><N><D><V><S><V><L><R><Y><G><H><R><P><G><R><D><D><R><M><T><T><H><V><G><L><T><A><R><A><L><G><A><D><Q><V><I><F><P><D><N><A><T><Q><S><A><E><T><V><S><D><I><V><S><R><F><G><G><P><F><D><V><E><R><T><D><G><L><N><A><T><I><R><E><W><S><G><T><V><I><H><L><T><M><Y><G><E><R><V><Q><D><V><T><E><V><I><R><E><T><C><L><H><H... | Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.<BOP> | Q18HD7 |
O59412 | TYW1_PYRHO | tRNA wyosine derivatives biosynthesis protein Taw1 | Pyrococcus | <M><M><E><M><I><T><I><K><P><G><K><I><T><V><Q><A><N><P><N><M><P><K><E><V><A><E><L><F><R><K><Q><H><Y><E><I><V><G><R><H><S><G><V><K><L><C><H><W><L><K><K><S><L><T><E><G><R><F><C><Y><K><Q><K><F><Y><G><I><H><S><H><R><C><L><Q><M><T><P><V><L><A><W><C><T><H><N><C><I><F><C><W><R><P><M><E><N><F><L><G><T><E><L><P><Q><P><W><D><D><P... | Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).<BOP> | O59412 |
Q0APU5 | TRPD_MARMM | Anthranilate phosphoribosyltransferase | Maricaulis | <M><Q><N><I><Y><L><C><L><T><A><F><A><R><G><T><Y><P><D><D><A><A><I><A><G><A><F><D><E><L><M><S><G><D><A><P><D><A><A><I><G><G><F><L><V><G><L><A><A><L><G><E><R><P><S><D><I><A><A><G><A><R><A><L><R><S><R><M><T><R><I><E><A><P><V><G><A><I><D><T><C><G><T><G><G><D><G><K><G><A><W><N><I><S><T><T><A><A><I><I><A><A><G><A><G><A><T><V... | Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP> | Q0APU5 |
Q8Z172 | ULAA_SALTI | Ascorbate-specific permease IIC component UlaA | Salmonella | <M><E><I><L><Y><N><I><F><T><I><F><F><N><Q><V><M><T><N><A><P><L><L><L><G><I><V><T><C><L><G><Y><I><L><L><R><K><S><V><S><V><I><I><K><G><T><I><K><T><I><I><G><F><M><L><L><Q><A><G><S><G><I><L><T><S><T><F><K><P><V><V><A><K><M><S><E><V><Y><G><I><N><G><A><I><S><D><T><Y><A><S><M><M><A><T><I><E><R><M><G><D><A><Y><S><W><V><G><Y><A... | The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.<BOP... | Q8Z172 |
A7H426 | TRUA_CAMJD | tRNA-uridine isomerase I | Campylobacter | <M><M><K><I><K><I><I><F><S><Y><D><G><S><A><F><L><G><S><A><T><Q><P><H><K><K><G><V><Q><D><V><L><S><E><A><L><S><H><L><G><I><F><S><P><L><L><M><A><S><R><T><D><K><G><V><H><A><S><Y><A><V><A><S><V><E><C><G><D><H><F><V><N><L><E><Y><L><Q><K><Q><L><N><K><F><S><H><P><F><I><H><I><K><K><I><E><K><V><K><D><D><F><E><V><R><F><D><V><K><S... | Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.<BOP> | A7H426 |
Q1Q8B0 | UVRC_PSYCK | Excinuclease ABC subunit C | Psychrobacter | <M><V><N><V><S><E><S><S><P><I><D><D><K><K><A><R><L><K><H><L><I><Q><R><L><P><N><L><P><G><V><Y><K><M><L><G><K><N><G><D><I><L><Y><V><G><K><A><K><S><L><K><S><R><V><N><S><Y><F><A><K><T><I><D><H><P><K><T><R><A><L><V><A><R><I><H><N><I><E><T><I><I><T><R><S><E><T><E><A><L><L><L><E><Q><N><L><I><K><E><Y><R><P><P><Y><N><V><L><L><R... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | Q1Q8B0 |
A2QWA2 | VPS27_ASPNC | Vacuolar protein sorting-associated protein 27 | Aspergillus subgen. Circumdati | <M><A><G><W><F><S><S><T><S><T><I><E><D><Q><V><E><K><A><T><A><S><S><L><E><D><I><A><L><N><L><E><I><S><D><L><I><R><S><K><G><V><Q><P><K><D><A><M><R><C><L><K><R><R><L><E><N><K><N><P><N><I><Q><L><A><T><L><K><L><T><D><T><C><V><K><N><G><G><T><H><F><L><A><E><I><A><S><R><E><F><M><D><N><L><V><S><L><L><K><T><E><G><A><P><L><N><S><D... | Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.<BOP> | A2QWA2 |
Q885T9 | UBIG_PSESM | 3-demethylubiquinone 3-O-methyltransferase | Pseudomonas | <M><S><N><V><D><R><A><E><I><A><K><F><E><A><L><A><H><R><W><W><D><R><E><S><E><F><K><P><L><H><D><I><N><P><L><R><V><N><W><I><D><E><R><A><N><L><A><G><K><K><V><L><D><V><G><C><G><G><G><I><L><S><E><A><M><A><L><R><G><A><T><V><T><G><I><D><M><G><E><A><P><L><A><V><A><Q><L><H><Q><L><E><S><G><V><S><V><E><Y><R><Q><I><T><A><E><D><L><A... | O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP> | Q885T9 |
P44401 | XYLB_HAEIN | Xylulose kinase | Haemophilus | <M><Y><I><G><I><D><C><G><T><Q><G><T><K><A><I><V><L><D><S><V><Q><K><K><V><I><G><V><G><Y><A><K><H><E><L><I><T><Q><S><N><G><R><R><E><Q><Q><P><N><W><W><I><E><A><L><Q><Q><A><L><Q><I><A><L><K><Q><A><K><N><S><P><H><F><S><P><N><L><V><K><G><I><G><I><S><G><Q><Q><H><G><L><V><M><L><D><K><N><D><R><P><L><Y><K><A><K><L><W><C><D><T><E... | Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.<BOP> | P44401 |
Q8EQG0 | TYSY_OCEIH | Thymidylate synthase | Oceanobacillus | <M><L><G><E><Q><A><Y><L><D><L><C><K><Q><I><F><K><T><G><E><Q><R><G><D><R><T><N><T><G><T><H><S><I><F><G><H><Q><I><R><F><D><L><N><K><G><F><P><L><L><T><T><K><R><V><P><F><R><L><V><A><S><E><L><L><W><F><I><K><G><D><T><N><I><R><Y><L><L><K><H><N><N><N><I><W><N><E><W><A><F><E><K><W><V><N><S><A><D><Y><Q><G><P><D><M><A><N><F><G><L... | Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell... | Q8EQG0 |
G5EFD5 | UNC71_CAEEL | Uncoordinated protein 71 | Caenorhabditis | <M><I><C><A><S><K><I><T><M><L><G><L><L><V><M><C><T><L><G><G><V><L><G><K><V><D><I><R><Q><T><T><A><N><K><A><F><M><E><T><M><R><A><D><G><Y><E><V><V><H><P><F><Q><I><R><D><K><N><E><R><I><G><I><D><T><R><N><Y><F><L><K><A><Q><E><H><Y><S><H><V><T><I><V><I><R><S><N><Q><L><G><R><L><K><L><V><L><E><R><N><N><F><I><F><L><N><Q><T><A><F... | Involved in the migration of sex myoblasts (progenitors of egg-laying muscles), Q neuroblasts and BDU interneurons during development . Involved in axon branching and guidance of neurons including GABAergic type D motor neurons . Promotes sex myoblast migration and positioning independently of gonad attraction cues . M... | G5EFD5 |
P21875 | VLP21_BORHE | Variable major outer membrane lipoprotein 21 | Borrelia | <M><R><K><R><I><S><A><I><I><N><K><L><N><I><S><I><M><M><M><I><V><V><L><M><I><G><C><G><Q><Q><P><E><A><G><K><T><G><A><A><G><G><E><K><Q><G><A><G><S><L><S><E><V><L><M><E><V><G><K><S><A><E><N><A><F><Y><S><F><L><E><L><V><S><D><T><L><G><F><T><A><K><S><T><T><K><K><E><D><V><G><G><Y><F><N><S><L><G><G><K><L><G><E><A><S><N><E><L><E... | The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.<BOP> | P21875 |
Q31EL5 | UPPP_HYDCU | Undecaprenyl pyrophosphate phosphatase | Hydrogenovibrio | <M><E><I><F><Q><A><A><I><L><G><I><I><E><G><L><T><E><F><L><P><I><S><S><T><G><H><L><I><V><V><S><D><W><L><G><I><E><Q><T><K><Q><N><T><A><F><E><V><I><I><Q><V><A><A><I><L><A><I><F><S><H><Y><K><E><K><F><S><L><Q><H><L><R><L><W><N><N><V><L><I><A><F><L><P><I><A><I><I><G><F><I><F><Q><D><T><V><K><A><F><F><T><I><E><T><V><A><W><F><F... | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.<BOP> | Q31EL5 |
Q32KS7 | ZN821_BOVIN | Zinc finger protein 821 | Bos | <M><S><R><R><K><Q><T><N><P><N><K><V><H><W><D><Q><V><F><A><G><L><E><E><Q><A><R><Q><A><M><M><K><T><D><F><P><G><D><L><G><S><Q><R><Q><A><I><Q><Q><L><R><D><Q><D><S><S><S><S><D><S><E><G><D><E><E><E><T><T><Q><D><E><V><S><S><H><T><S><E><E><D><G><G><V><V><K><V><E><K><E><L><E><N><A><E><Q><P><V><G><G><K><K><V><V><E><H><E><V><T><E... | May be involved in transcriptional regulation.<BOP> | Q32KS7 |
Q17134 | TBXT1_BRAFL | Brachyury protein homolog 1 | Branchiostoma | <M><S><S><A><E><T><M><K><Q><P><T><A><A><S><P><D><Q><F><S><V><S><H><L><L><S><A><V><E><S><E><I><S><A><G><S><E><K><G><D><P><T><E><R><D><L><K><I><T><L><E><E><K><P><L><W><D><K><F><N><A><L><T><N><E><M><I><V><T><K><N><G><R><R><M><F><P><V><L><K><V><N><V><S><G><L><D><P><N><A><M><Y><S><F><L><L><D><F><T><A><A><D><N><H><R><W><K><Y... | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation.<BOP> | Q17134 |
Q5P7U3 | UBIG_AROAE | 3-demethylubiquinone 3-O-methyltransferase | Aromatoleum | <M><N><M><N><A><D><P><A><E><L><Q><K><F><S><E><L><A><H><R><W><W><D><T><T><S><E><F><K><P><L><H><E><I><N><P><L><R><L><D><W><I><D><R><N><A><G><L><A><G><K><R><V><L><D><I><G><C><G><G><G><I><L><S><E><S><M><A><A><A><G><A><H><V><T><G><I><D><L><S><E><K><A><L><G><V><A><R><L><H><L><F><E><S><G><Q><K><V><D><Y><H><H><A><S><A><E><E><F... | O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP> | Q5P7U3 |
A6MM37 | YCF3_BUXMI | Photosystem I assembly protein Ycf3 | Buxus | <M><S><R><S><R><I><N><G><N><F><I><D><K><T><F><S><I><V><A><N><I><L><L><R><I><I><P><T><T><S><G><E><K><E><A><F><T><Y><Y><R><D><G><M><S><A><Q><S><E><G><N><Y><A><E><A><L><Q><N><Y><Y><E><A><T><R><L><E><I><D><P><Y><D><R><S><Y><I><L><Y><N><I><G><L><I><H><T><S><N><G><E><H><T><K><A><L><E><Y><Y><S><R><A><L><E><R><N><P><F><L><P><Q... | Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits.<BOP> | A6MM37 |
Q747I7 | UVRC_GEOSL | Excinuclease ABC subunit C | Geobacter | <M><F><D><T><K><R><L><T><T><L><P><D><A><P><G><V><Y><L><M><K><G><N><G><G><D><I><L><Y><V><G><K><A><K><S><L><R><K><R><V><R><S><Y><F><S><K><G><G><E><S><R><Y><H><I><R><F><L><V><G><R><V><A><D><I><D><V><I><V><T><D><T><E><K><E><A><L><L><L><E><N><T><L><I><K><E><H><R><P><R><Y><N><L><D><L><R><D><D><K><T><Y><F><S><L><R><L><D><M><N... | The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP> | Q747I7 |
Q9UKP6 | UR2R_HUMAN | Urotensin II receptor | Homo | <M><A><L><T><P><E><S><P><S><S><F><P><G><L><A><A><T><G><S><S><V><P><E><P><P><G><G><P><N><A><T><L><N><S><S><W><A><S><P><T><E><P><S><S><L><E><D><L><V><A><T><G><T><I><G><T><L><L><S><A><M><G><V><V><G><V><V><G><N><A><Y><T><L><V><V><T><C><R><S><L><R><A><V><A><S><M><Y><V><Y><V><V><N><L><A><L><A><D><L><L><Y><L><L><S><I><P><F><I... | High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.<BOP> | Q9UKP6 |
Q9UL33 | TPC2L_HUMAN | Trafficking protein particle complex subunit 2-like protein | Homo | <M><A><V><C><I><A><V><I><A><K><E><N><Y><P><L><Y><I><R><S><T><P><T><E><N><E><L><K><F><H><Y><M><V><H><T><S><L><D><V><V><D><E><K><I><S><A><M><G><K><A><L><V><D><Q><R><E><L><Y><L><G><L><L><Y><P><T><E><D><Y><K><V><Y><G><Y><V><T><N><S><K><V><K><F><V><M><V><V><D><S><S><N><T><A><L><R><D><N><E><I><R><S><M><F><R><K><L><H><N><S><Y... | Plays a role in vesicular transport from endoplasmic reticulum to Golgi.<BOP> | Q9UL33 |
Q9GKZ4 | TRAM1_BOVIN | Translocating chain-associated membrane protein 1 | Bos | <M><A><I><R><K><K><S><S><K><N><P><P><V><L><S><H><E><F><V><L><Q><N><H><A><D><I><V><S><C><V><A><M><V><F><L><L><G><L><M><F><E><I><T><A><K><V><S><I><I><F><V><T><L><Q><Y><N><V><T><L><P><A><T><E><E><Q><A><T><E><S><A><F><L><Y><Y><Y><G><I><K><D><L><A><T><V><F><F><Y><M><L><V><A><I><I><I><H><A><I><I><Q><E><Y><V><L><D><K><I><N><R... | Involved in the translocation of nascent protein chains into or through the endoplasmic reticulum (ER) membrane by facilitating the proper chain positioning at the SEC61 channel. Regulates the exposure of nascent secretory protein chain to the cytosol during translocation into the ER. May affect the phospholipid bilaye... | Q9GKZ4 |
Q5XI41 | TRAM1_RAT | Translocating chain-associated membrane protein 1 | Rattus | <M><A><I><R><K><K><S><N><K><N><P><P><V><L><S><H><E><F><V><L><Q><N><H><A><D><I><V><S><C><L><A><M><L><F><L><L><G><L><M><F><E><I><T><A><K><G><A><I><I><F><V><A><L><Q><Y><N><V><T><R><P><A><T><E><E><Q><A><A><E><S><A><S><L><Y><Y><Y><G><I><K><D><L><A><T><V><F><F><Y><M><L><V><A><I><I><V><H><A><I><I><Q><E><Y><V><L><D><K><I><N><R... | Involved in the translocation of nascent protein chains into or through the endoplasmic reticulum (ER) membrane by facilitating the proper chain positioning at the SEC61 channel. Regulates the exposure of nascent secretory protein chain to the cytosol during translocation into the ER. May affect the phospholipid bilaye... | Q5XI41 |
O75541 | ZN821_HUMAN | Zinc finger protein 821 | Homo | <M><S><R><R><K><Q><T><N><P><N><K><V><H><W><D><Q><V><F><A><G><L><E><E><Q><A><R><Q><A><M><M><K><T><D><F><P><G><D><L><G><S><Q><R><Q><A><I><Q><Q><L><R><D><Q><D><S><S><S><S><D><S><E><G><D><E><E><E><T><T><Q><D><E><V><S><S><H><T><S><E><E><D><G><G><V><V><K><V><E><K><E><L><E><N><T><E><Q><P><V><G><G><N><E><V><V><E><H><E><V><T><G... | May be involved in transcriptional regulation.<BOP> | O75541 |
Q9I748 | TSSC1_PSEAE | Sheath protein HsiC1 | Pseudomonas | <M><A><E><L><S><T><E><N><L><A><Q><G><Q><T><T><T><E><Q><T><S><E><F><A><S><L><L><L><Q><E><F><K><P><K><T><E><R><A><R><E><A><V><E><T><A><V><R><T><L><A><E><H><A><L><E><Q><T><S><L><I><S><N><D><A><I><K><S><I><E><S><I><I><A><A><L><D><A><K><L><T><A><Q><V><N><L><I><M><H><H><A><D><F><Q><Q><L><E><S><A><W><R><G><L><H><Y><L><V><N><N... | Core component of the H1 type VI (H1-T6SS) secretion system that plays a role in the release of toxins targeting both eukaryotic and prokaryotic species. Forms the sheath of the structure by assembling into tubules together with TssB1 resulting in the stacking of cogwheel-like structures showing predominantly a 12-fold... | Q9I748 |
P37617 | ZNTA_ECOLI | Zn(2+)/Cd(2+)/Pb(2+) export ATPase | Escherichia | <M><S><T><P><D><N><H><G><K><K><A><P><Q><F><A><A><F><K><P><L><T><T><V><Q><N><A><N><D><C><C><C><D><G><A><C><S><S><T><P><T><L><S><E><N><V><S><G><T><R><Y><S><W><K><V><S><G><M><D><C><A><A><C><A><R><K><V><E><N><A><V><R><Q><L><A><G><V><N><Q><V><Q><V><L><F><A><T><E><K><L><V><V><D><A><D><N><D><I><R><A><Q><V><E><S><A><L><Q><K><A... | Confers resistance to zinc, cadmium and lead . Couples the hydrolysis of ATP with the export of zinc, cadmium or lead, with highest activity when the metals are present as metal-thiolate complexes . Can also bind nickel, copper, cobalt and mercury .<BOP> | P37617 |
Q89UZ9 | YACG_BRADU | DNA gyrase inhibitor YacG | Bradyrhizobium | <M><D><D><Q><V><K><M><P><T><G><P><L><K><T><C><P><I><C><G><K><P><A><V><Q><A><T><H><P><F><C><S><S><R><C><R><D><V><D><L><N><R><W><L><K><G><S><Y><V><I><P><G><R><D><D><E><V><D><D><V><E> | Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.<BOP> | Q89UZ9 |
P36987 | TX22E_PLETR | Plectoxin-13 | Plectreurys | <A><L><K><C><Q><G><W><V><D><Y><C><N><G><N><V><E><C><C><N><E><C><V><M><Y> | Potent toxin that may paralyze and/or kill insect pests such as H.virescens (lepidoptera), S.exigua (beet armyworm) and M.sexta (tobacco hornworm).<BOP> | P36987 |
B0TJ18 | UBIB_SHEHH | Ubiquinone biosynthesis protein UbiB | Shewanella | <M><T><A><K><N><I><R><R><A><Y><H><V><I><R><T><A><L><H><Y><G><L><D><D><L><I><P><S><K><L><T><P><W><Y><F><K><L><F><R><Y><S><F><F><W><L><R><N><Q><H><K><D><K><V><G><G><E><R><L><K><L><A><M><Q><E><L><G><P><V><Y><I><K><F><G><Q><M><L><S><T><R><R><D><L><L><S><D><E><W><A><E><E><L><A><M><L><Q><D><R><V><P><P><F><D><S><A><I><A><R><A... | Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.<BOP> | B0TJ18 |
O31617 | THIS_BACSU | Thiamine biosynthesis protein ThiS | Bacillus | <M><L><Q><L><N><G><K><D><V><K><W><K><K><D><T><G><T><I><Q><D><L><L><A><S><Y><Q><L><E><N><K><I><V><I><V><E><R><N><K><E><I><I><G><K><E><R><Y><H><E><V><E><L><C><D><R><D><V><I><E><I><V><H><F><V><G><G><G> | Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate.<BOP> | O31617 |
Q8N554 | ZN276_HUMAN | Zinc finger protein 477 | Homo | <M><K><R><D><R><L><G><R><F><L><S><P><G><S><S><R><Q><C><G><A><S><D><G><G><G><G><V><S><R><T><R><G><R><P><S><L><S><G><G><P><R><V><D><G><A><T><A><R><R><A><W><G><P><V><G><S><C><G><D><A><G><E><D><G><A><D><E><A><G><A><G><R><A><L><A><M><G><H><C><R><L><C><H><G><K><F><S><S><R><S><L><R><S><I><S><E><R><A><P><G><A><S><M><E><R><P><S... | May be involved in transcriptional regulation.<BOP> | Q8N554 |
Q8EV76 | TIG_MALP2 | PPIase | Malacoplasma | <M><K><I><T><S><V><K><N><E><K><E><L><V><S><F><E><I><D><L><S><E><K><K><W><N><E><F><L><D><K><E><I><L><K><A><S><K><N><L><K><M><P><G><Y><R><P><G><K><V><P><L><E><I><A><K><K><N><I><N><M><P><V><C><F><V><N><A><L><S><S><A><R><E><R><I><E><D><W><I><I><D><Q><D><E><F><K><K><M><A><D><E><I><C><D><F><D><P><V><T><S><K><P><N><N><S><N><N... | Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP> | Q8EV76 |
Q6FYW7 | VIRB4_BARQU | Type IV secretion system protein virB4 | Bartonella | <M><S><I><M><K><R><E><S><L><P><E><E><Y><I><P><Y><I><R><H><V><N><Q><H><V><I><A><L><N><S><R><C><L><M><T><V><M><A><V><E><G><V><N><F><D><T><A><D><I><N><H><L><N><S><L><H><N><Q><L><N><T><L><L><R><N><I><A><D><E><R><V><A><L><Y><S><H><I><I><R><R><R><E><T><I><Y><P><E><S><R><F><F><S><S><F><A><A><T><L><D><E><K><Y><K><K><K><M><V><S... | Component of the type IV secretion system VirB/VirD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function. Altogether with virB11, may be implicated in providing the energy, via hydrolysis of ATP, for the assembly of secretion system and substrate transport.<BOP> | Q6FYW7 |
A4JCZ0 | THIC_BURVG | Thiamine biosynthesis protein ThiC | Burkholderia cepacia complex | <M><N><A><N><P><K><F><L><S><A><D><A><H><V><D><A><A><A><V><A><P><L><P><N><S><R><K><V><Y><V><T><G><S><Q><P><D><I><R><V><P><M><R><E><I><T><Q><A><D><T><P><T><G><F><G><G><E><K><N><P><P><I><Y><V><Y><D><T><S><G><P><Y><T><D><P><D><A><K><I><D><I><R><A><G><L><P><A><L><R><Q><R><W><I><E><A><R><G><D><T><E><V><L><D><G><L><S><S><G><Y... | Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.<BOP> | A4JCZ0 |
Q1C570 | UNG_YERPA | Uracil-DNA glycosylase | Yersinia | <M><S><P><S><L><T><W><H><D><V><I><G><Q><E><K><E><Q><P><Y><F><K><D><T><L><A><Y><V><A><A><E><R><R><A><G><K><T><I><Y><P><P><Q><K><D><I><F><N><A><F><R><L><T><E><L><D><Q><V><K><V><V><I><L><G><Q><D><P><Y><H><G><P><N><Q><A><H><G><L><S><F><S><V><L><P><G><V><P><A><P><P><S><L><G><N><I><Y><K><E><L><V><T><D><I><P><G><F><Q><R><P><N... | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.<BOP> | Q1C570 |
Q479P4 | ZAPD_DECAR | Z ring-associated protein D | Dechloromonas | <M><I><T><Y><E><Y><P><F><N><E><R><I><R><T><L><L><R><L><E><D><L><F><E><K><T><A><Y><F><T><Q><E><D><G><A><L><E><H><H><A><A><L><V><S><M><F><E><I><L><E><V><A><G><R><A><D><L><K><M><D><L><I><Q><E><L><E><R><Q><R><Q><T><L><L><A><F><R><N><N><P><D><I><S><E><E><A><L><S><G><A><L><Y><E><I><E><Q><S><S><A><A><L><L><G><M><A><G><K><I><G... | Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.<BOP> | Q479P4 |
O27520 | TRPB2_METTH | Tryptophan synthase beta chain 2 | Methanothermobacter | <M><M><N><K><I><V><L><D><E><N><E><I><P><K><K><W><Y><N><I><N><P><D><L><P><S><P><L><P><E><P><K><N><P><E><G><G><K><N><I><E><N><L><P><R><V><F><S><R><G><V><L><E><Q><E><M><S><M><E><R><W><I><K><I><P><R><E><V><M><D><V><Y><K><M><I><G><R><P><T><P><L><F><R><A><K><G><L><E><E><M><L><D><T><P><A><R><I><Y><Y><K><R><E><D><Y><S><P><T><G... | The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP> | O27520 |
Q9UK55 | ZPI_HUMAN | Serpin A10 | Homo | <M><K><V><V><P><S><L><L><L><S><V><L><L><A><Q><V><W><L><V><P><G><L><A><P><S><P><Q><S><P><E><T><P><A><P><Q><N><Q><T><S><R><V><V><Q><A><P><K><E><E><E><E><D><E><Q><E><A><S><E><E><K><A><S><E><E><E><K><A><W><L><M><A><S><R><Q><Q><L><A><K><E><T><S><N><F><G><F><S><L><L><R><K><I><S><M><R><H><D><G><N><M><V><F><S><P><F><G><M><S><L... | Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors.<BOP> | Q9UK55 |
A0B5H8 | TBP_METTP | TATA-box factor | Methanothrix | <M><E><S><T><I><N><I><E><N><V><V><A><S><T><K><L><A><D><E><F><D><L><V><K><I><E><S><E><L><E><G><A><E><Y><N><K><E><K><F><P><G><L><V><Y><R><V><K><S><P><K><A><A><F><L><I><F><T><S><G><K><V><V><C><T><G><A><K><N><V><E><D><V><R><T><V><I><T><N><M><A><R><T><L><K><S><I><G><F><D><N><I><N><L><E><P><E><I><H><V><Q><N><I><V><A><S><A><D... | General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.<BOP> | A0B5H8 |
Q8YVT9 | TGT_NOSS1 | tRNA-guanine transglycosylase | Nostoc | <M><S><A><I><F><S><F><Q><S><L><A><R><C><S><Q><T><K><A><R><S><G><I><F><L><T><P><H><G><I><V><E><T><P><R><F><M><P><V><G><T><L><A><N><V><K><T><V><T><P><A><Q><L><K><E><T><G><A><Q><M><V><L><S><N><T><Y><H><L><H><L><Q><P><G><E><A><I><V><A><G><G><G><G><L><H><K><F><M><G><W><N><G><P><M><L><T><D><S><G><G><F><Q><V><F><S><L><S><E><M... | Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th... | Q8YVT9 |
Q6D855 | TGT_PECAS | tRNA-guanine transglycosylase | Pectobacterium | <M><K><Y><E><L><Q><T><T><D><G><R><A><R><R><G><R><L><I><F><E><R><G><V><V><E><T><P><A><F><M><P><V><G><T><Y><G><T><V><K><G><M><T><P><E><E><V><K><E><T><G><A><Q><I><L><L><G><N><T><F><H><L><W><L><R><P><G><Q><E><I><M><K><L><H><G><D><L><H><D><F><M><N><W><H><G><P><I><L><T><D><S><G><G><F><Q><V><F><S><L><G><D><I><R><K><I><T><E><Q... | Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th... | Q6D855 |
Q88DP1 | THIE_PSEPK | Thiamine-phosphate pyrophosphorylase | Pseudomonas | <M><K><L><R><G><L><Y><A><I><T><D><S><Q><L><L><A><G><R><F><L><S><H><V><E><A><A><L><E><G><G><V><C><L><L><Q><Y><R><D><K><T><D><D><A><A><R><R><L><R><E><A><E><G><L><M><K><L><C><E><R><Y><G><T><Q><L><L><I><N><D><D><A><E><L><A><A><R><L><G><V><G><V><H><L><G><Q><T><D><G><P><L><T><P><A><R><A><L><L><G><R><Q><A><I><I><G><S><T><C><H... | Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP> | Q88DP1 |
P18729 | ZG57_XENLA | Gastrula zinc finger protein XlCGF57.1 | Xenopus | <T><G><G><K><S><Y><T><C><T><E><C><G><K><G><F><I><K><K><S><R><L><V><T><H><M><K><I><H><T><G><E><T><H><F><I><C><T><E><C><G><K><G><F><S><Q><K><G><I><L><Q><T><H><M><K><T><H><T><G><E><K><P><F><T><C><T><E><C><G><K><N><F><A><Q><I><T><T><L><L><R><H><L><T><I><H><T><G><E><K><P><F><S><C><T><E><C><G><K><H><F><A><H><K><G><H><L><V><S... | May be involved in transcriptional regulation.<BOP> | P18729 |
Q6ND54 | TSAD_RHOPA | tRNA threonylcarbamoyladenosine biosynthesis protein TsaD | Rhodopseudomonas | <M><T><S><E><Q><A><L><L><V><L><G><I><E><T><T><C><D><E><T><A><A><A><V><V><E><R><R><A><D><G><S><G><R><L><L><S><N><I><V><R><S><Q><T><D><E><H><A><P><F><G><G><V><V><P><E><I><A><A><R><A><H><V><D><V><L><D><G><I><I><A><A><A><M><N><E><A><G><V><A><F><A><S><L><S><G><V><A><A><A><A><G><P><G><L><I><G><G><V><I><V><G><L><T><T><A><K><A... | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca... | Q6ND54 |
Q4I1B1 | VAC8_GIBZE | Vacuolar protein 8 | Fusarium | <M><G><I><C><S><S><T><C><C><G><G><R><A><R><D><G><L><Y><E><P><V><L><A><D><S><E><R><E><A><V><A><D><L><L><Q><Y><L><E><N><R><G><E><T><D><F><F><S><G><E><P><L><R><A><L><S><T><L><V><F><S><E><N><I><D><L><Q><R><S><A><S><L><T><F><A><E><I><T><E><R><D><V><R><E><V><D><R><D><T><L><E><P><I><L><F><L><L><Q><S><P><D><I><E><V><Q><R><A><A... | Functions in both vacuole inheritance and protein targeting from the cytoplasm to vacuole.<BOP> | Q4I1B1 |
Q9RCA5 | YIDC1_HALH5 | Membrane protein YidC 1 | Halalkalibacterium (ex Joshi et al. 2022) | <M><Y><R><K><F><G><M><A><A><M><L><V><S><I><L><L><L><M><T><G><C><F><N><V><N><E><P><I><N><A><Q><S><E><G><I><W><D><S><Y><F><V><Y><P><L><S><W><L><M><I><Y><F><A><N><A><F><N><G><S><F><G><L><A><I><I><V><V><T><L><L><I><R><L><L><I><L><P><L><M><I><K><Q><L><K><S><T><R><A><M><Q><A><L><Q><P><E><M><Q><A><L><R><E><K><Y><S><A><K><D><Q... | Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.<BOP> | Q9RCA5 |
Q9V150 | TRPB2_PYRAB | Tryptophan synthase beta chain 2 | Pyrococcus | <M><K><V><V><L><P><D><G><R><I><P><R><R><W><Y><N><I><L><P><D><L><P><E><P><L><D><P><P><L><D><P><E><T><E><E><P><I><D><I><E><K><L><K><R><I><F><A><E><E><L><V><K><Q><E><I><S><R><E><R><Y><I><E><I><P><G><E><L><R><K><L><Y><S><K><I><G><R><P><T><P><L><F><R><A><T><N><L><E><K><L><L><G><T><P><A><R><I><Y><F><K><Y><E><G><A><T><V><T><G... | The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.<BOP> | Q9V150 |
O05960 | YBEY_RICPR | Endoribonuclease YbeY | typhus group | <M><I><N><V><E><I><I><R><N><Y><N><K><W><R><E><H><R><K><I><N><K><G><L><I><K><K><I><T><Q><N><V><L><V><R><F><D><N><F><S><K><I><K><Q><F><E><L><S><I><L><L><T><N><T><A><E><I><L><T><L><N><Q><Q><F><R><S><I><E><K><A><T><N><V><L><S><F><P><N><N><E><L><N><W><H><N><L><Y><S><K><L><E><F><L><Y><Y><S><D><Y><M><H><L><G><D><I><A><F><C><Y... | Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP> | O05960 |
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