accession
stringlengths
6
10
name
stringlengths
6
11
Full Name
stringlengths
1
147
taxon
stringlengths
3
46
sequence
stringlengths
48
8.26k
function
stringlengths
11
5.52k
AlphaFoldDB
stringlengths
6
10
B5FDT8
UBIG_ALIFM
3-demethylubiquinone 3-O-methyltransferase
Aliivibrio
<M><T><Q><Q><L><N><V><D><P><A><E><I><K><K><F><E><D><M><A><S><R><W><W><D><L><E><G><E><F><K><P><L><H><Q><I><N><P><L><R><L><N><Y><V><L><E><N><A><N><G><L><F><G><K><K><V><L><D><V><G><C><G><G><G><I><L><A><E><S><M><A><K><Q><G><A><D><V><V><G><L><D><M><G><K><E><P><L><T><V><A><R><L><H><A><L><E><T><G><T><K><L><E><Y><V><Q><S><T><A...
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP>
B5FDT8
O95670
VATG2_HUMAN
Vacuolar proton pump subunit G 2
Homo
<M><A><S><Q><S><Q><G><I><Q><Q><L><L><Q><A><E><K><R><A><A><E><K><V><A><D><A><R><K><R><K><A><R><R><L><K><Q><A><K><E><E><A><Q><M><E><V><E><Q><Y><R><R><E><R><E><H><E><F><Q><S><K><Q><Q><A><A><M><G><S><Q><G><N><L><S><A><E><V><E><Q><A><T><R><R><Q><V><Q><G><M><Q><S><S><Q><Q><R><N><R><E><R><V><L><A><Q><L><L><G><M><V><C><D><V><R...
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types,...
O95670
A5VYH8
UPP_PSEP1
UPRTase
Pseudomonas
<M><P><T><R><E><I><R><H><P><L><I><R><H><K><L><G><L><M><R><R><A><D><I><S><T><K><N><F><R><E><L><A><Q><E><V><G><A><L><L><T><Y><E><A><T><Q><D><L><P><L><E><T><Y><E><I><D><G><W><C><G><K><V><S><V><E><K><I><A><G><K><K><I><T><V><V><P><I><L><R><A><G><I><G><M><L><D><G><V><L><S><L><I><P><G><A><K><V><S><A><V><G><V><A><R><N><E><E><T...
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.<BOP>
A5VYH8
Q9WYV0
UVRA_THEMA
Excinuclease ABC subunit A
Thermotoga
<M><N><E><I><V><V><K><G><A><R><V><H><N><L><K><N><I><T><V><R><I><P><K><N><R><L><V><V><I><T><G><V><S><G><S><G><K><S><S><L><A><M><D><T><I><Y><A><E><G><Q><R><R><Y><L><E><S><L><S><T><Y><A><R><Q><F><L><G><N><L><K><K><P><D><V><D><E><I><E><G><L><S><P><A><I><A><I><D><Q><K><T><V><S><H><N><P><R><S><T><V><G><T><V><T><E><I><Y><D><Y...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.<BOP>
Q9WYV0
Q8NZU4
TRMB_STRP8
tRNA(m7G46)-methyltransferase
Streptococcus
<M><R><V><R><K><R><K><G><A><E><K><H><L><A><N><N><P><H><Y><V><I><L><N><P><E><D><A><K><G><R><W><H><D><V><F><G><N><D><R><P><I><H><I><E><V><G><S><G><K><G><G><F><I><T><G><M><A><L><K><N><P><D><I><N><Y><I><G><I><D><I><Q><L><S><V><L><S><Y><A><L><D><K><V><L><A><S><E><V><P><N><V><K><L><L><R><V><D><G><S><S><L><T><N><Y><F><E><D><G...
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<BOP>
Q8NZU4
Q7VRS7
UREF_BLOFL
Urease accessory protein UreF
Candidatus Blochmannia
<M><N><I><H><R><E><C><R><S><L><L><S><L><I><Q><I><V><S><G><N><L><P><T><G><G><F><S><Y><S><K><G><L><E><S><A><I><E><Y><G><W><V><K><S><L><E><D><F><L><N><W><Q><K><Q><W><I><H><E><Q><L><I><Y><I><D><W><P><M><L><K><R><C><Y><Y><Y><T><K><I><N><D><S><K><N><F><K><K><C><A><L><Q><I><L><S><Y><R><D><T><Y><E><L><R><L><E><E><Q><R><R><G><K...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
Q7VRS7
Q9NZ09
UBAP1_HUMAN
Nasopharyngeal carcinoma-associated gene 20 protein
Homo
<M><A><S><K><K><L><G><A><D><F><H><G><T><F><S><Y><L><D><D><V><P><F><K><T><G><D><K><F><K><T><P><A><K><V><G><L><P><I><G><F><S><L><P><D><C><L><Q><V><V><R><E><V><Q><Y><D><F><S><L><E><K><K><T><I><E><W><A><E><E><I><K><K><I><E><E><A><E><R><E><A><E><C><K><I><A><E><A><E><A><K><V><N><S><K><S><G><P><E><G><D><S><K><M><S><F><S><K><T...
Component of the ESCRT-I complex, a regulator of vesicular trafficking process . Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) . Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR an...
Q9NZ09
A1VJ15
TGT_POLNA
tRNA-guanine transglycosylase
Polaromonas
<M><L><E><F><E><V><L><K><T><D><P><A><T><V><D><S><E><G><A><Y><L><G><S><Y><A><R><R><G><Q><L><T><L><N><H><G><V><V><Q><T><P><I><F><M><P><V><G><T><Y><G><T><V><K><G><V><T><P><Q><S><L><H><D><M><N><A><Q><I><I><L><G><N><T><F><H><L><W><M><R><P><G><L><D><V><V><A><Q><F><G><G><L><H><K><F><E><S><W><H><K><P><I><L><T><D><S><G><G><F><Q...
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks th...
A1VJ15
Q5VY80
ULBP6_HUMAN
Retinoic acid early transcript 1L protein
Homo
<M><A><A><A><A><I><P><A><L><L><L><C><L><P><L><L><F><L><L><F><G><W><S><R><A><R><R><D><D><P><H><S><L><C><Y><D><I><T><V><I><P><K><F><R><P><G><P><R><W><C><A><V><Q><G><Q><V><D><E><K><T><F><L><H><Y><D><C><G><N><K><T><V><T><P><V><S><P><L><G><K><K><L><N><V><T><M><A><W><K><A><Q><N><P><V><L><R><E><V><V><D><I><L><T><E><Q><L><L><D...
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.<BOP>
Q5VY80
Q95WA2
TCTP_SCHMA
Histamine-releasing factor
Schistosoma
<M><I><V><Y><K><D><M><I><T><E><D><E><M><F><T><D><S><H><C><P><R><V><V><A><D><F><F><Y><E><V><D><S><R><F><T><T><V><S><S><N><V><D><G><R><L><I><G><A><N><P><S><G><E><G><G><E><D><E><N><V><D><D><T><S><K><R><V><I><D><L><V><H><A><N><G><F><I><S><V><P><F><D><Q><K><S><Y><K><A><H><L><N><L><Y><L><K><T><I><I><E><R><L><Q><K><T><D><P><D...
Involved in calcium binding and microtubule stabilization.<BOP>
Q95WA2
Q5R5J8
ZDHC9_PONAB
Zinc finger DHHC domain-containing protein 9
Pongo
<M><S><V><M><V><V><R><K><K><V><T><R><K><W><E><K><L><P><G><R><N><T><F><C><C><D><G><R><V><M><M><A><R><Q><K><G><I><F><Y><L><T><L><F><L><I><L><G><T><C><T><L><F><F><A><F><E><C><R><Y><L><A><V><Q><Q><S><P><A><I><P><V><F><A><A><M><L><F><L><F><S><M><A><T><L><L><R><A><S><F><S><D><P><G><V><I><P><R><A><L><P><D><E><A><A><F><I><E><M...
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS. May have a palmitoyltransferase activity toward the beta-2 adrenergic receptor/ADRB2 and therefore regulate G protein-coupled receptor signa...
Q5R5J8
Q813X6
TOX1_BACCR
Ribonuclease BC_0920
Bacillus cereus group
<M><S><L><N><M><Y><L><G><E><V><Q><G><Q><T><Q><S><M><N><A><V><C><N><A><T><I><Q><G><M><E><Q><V><I><Q><S><I><D><A><F><A><I><D><T><V><L><Q><G><Q><T><Y><S><S><A><K><S><F><F><V><Q><T><F><R><P><L><A><Q><G><I><I><Y><L><C><E><E><L><I><R><Q><N><D><A><F><P><S><Q><F><Q><S><Q><V><A><S><T><D><V><I><E><Q><E><I><L><E><Q><I><R><E><I><D...
Toxic component of an LXG toxin-immunity module. The C-terminus (residues 322-545) has RNase activity in E.coli which is neutralized by cognate immunity protein BC_0921, but not by immunity proteins specific to other toxins with the LXG domain . Degrades 5S rRNA and several tRNAs in vitro; cleavage is endonucleolytic w...
Q813X6
A1U6H0
TRPD_MARN8
Anthranilate phosphoribosyltransferase
Marinobacter
<M><D><M><K><Q><A><L><N><R><I><A><S><N><L><D><L><S><R><D><E><M><K><D><V><M><R><I><V><M><N><G><E><A><T><D><A><Q><I><G><A><F><L><M><G><L><R><L><K><S><E><T><I><D><E><I><T><G><A><T><E><V><M><R><E><L><A><T><G><V><T><V><N><A><E><P><L><V><D><I><V><G><T><G><G><D><G><A><N><L><F><N><V><S><S><A><A><S><F><V><V><A><A><A><G><G><Y><V...
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).<BOP>
A1U6H0
B1JX27
UREF_BURCC
Urease accessory protein UreF
Burkholderia cepacia complex
<M><T><T><T><E><L><V><V><L><L><H><L><A><S><P><A><L><P><I><G><A><Y><S><Y><S><Q><G><L><E><A><A><L><D><A><N><L><I><R><D><A><D><S><A><R><D><W><I><A><S><G><L><T><D><V><L><A><H><G><E><L><P><F><L><A><H><Q><L><A><R><W><Q><T><H><D><T><H><A><L><A><A><E><N><A><W><F><V><A><S><R><E><S><A><E><L><R><R><E><T><E><Q><M><G><W><S><L><A><Q...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
B1JX27
B1Z8R3
UREG2_METPB
Urease accessory protein UreG 2
Methylorubrum
<M><K><K><I><T><R><I><G><I><G><G><P><V><G><S><G><K><T><A><V><I><E><T><I><T><P><R><L><I><E><R><G><I><K><P><L><I><I><T><N><D><V><V><T><T><E><D><A><K><Q><V><R><R><T><L><N><G><V><L><I><E><E><K><I><V><G><V><E><T><G><A><C><P><H><T><A><V><R><E><D><P><S><M><N><I><A><A><V><E><E><L><E><D><K><Y><P><D><S><D><V><I><L><I><E><S><G><G...
Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP>
B1Z8R3
Q73FE5
TILS_BACC1
tRNA(Ile)-lysidine synthetase
Bacillus cereus group
<M><K><D><T><F><V><E><K><V><D><D><F><V><K><Q><H><D><V><L><K><E><R><S><T><I><V><V><G><V><S><G><G><P><D><S><V><A><L><L><Y><Y><L><L><E><K><R><A><A><K><Q><F><E><I><V><V><A><H><V><D><H><M><F><R><G><D><E><S><H><E><D><L><Q><F><V><Q><D><L><C><K><E><L><G><V><I><C><E><T><I><R><I><N><V><S><Q><Y><Q><Q><Q><Y><G><M><N><A><Q><V><A><A...
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP>
Q73FE5
A1K668
YCIB_AZOSB
Inner membrane-spanning protein YciB
Azoarcus
<M><K><F><F><L><D><L><L><P><V><I><L><F><F><V><A><Y><K><F><A><G><A><A><P><D><D><S><H><A><L><V><A><Q><F><L><G><A><G><I><S><P><S><Q><A><P><I><L><I><A><T><A><V><A><I><A><A><T><L><A><Q><V><L><I><V><W><L><R><H><G><K><V><D><K><M><L><W><V><S><L><A><I><I><T><L><F><G><G><A><T><L><V><F><H><N><P><T><F><I><K><W><K><P><T><V><F><Y><W...
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.<BOP>
A1K668
B1YUF7
UREF_BURA4
Urease accessory protein UreF
Burkholderia cepacia complex
<M><T><T><T><E><L><V><A><L><L><H><L><A><S><P><A><L><P><I><G><A><F><S><Y><S><Q><G><F><E><A><A><L><D><A><N><L><I><R><D><A><D><T><A><R><D><W><I><A><S><G><L><T><D><V><L><A><H><G><E><L><P><F><L><A><H><Q><L><A><R><W><H><A><H><D><A><D><A><L><A><R><E><N><A><W><F><I><A><S><R><E><S><A><E><L><R><R><E><T><E><Q><M><G><W><S><L><A><Q...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
B1YUF7
Q5C8T6
TRIM5_GORGO
TRIM5alpha
Gorilla
<M><A><S><G><I><L><V><N><V><K><E><E><V><T><C><P><I><C><L><E><L><L><T><Q><P><L><S><L><D><C><G><H><S><F><C><Q><A><C><L><T><A><N><H><E><K><S><M><L><D><K><G><E><S><S><C><P><V><C><R><I><S><Y><Q><P><E><N><I><R><P><N><R><H><V><A><N><I><V><E><K><L><R><E><V><K><L><S><P><E><G><Q><K><V><D><H><C><A><R><H><G><E><K><L><L><L><F><C><Q...
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses. Blocks viral replication early in the life cycle, after viral entry but before reverse transcription. In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates i...
Q5C8T6
A6RIB9
TVP38_BOTFB
Golgi apparatus membrane protein tvp38
Botrytis
<M><P><A><D><Y><S><S><T><A><R><A><L><A><L><P><I><S><P><L><E><T><P><S><S><P><D><Q><H><V><E><R><P><P><W><S><R><R><I><S><S><N><V><R><R><A><N><N><S><A><S><P><Y><S><N><Q><P><T><T><S><F><K><D><Q><I><L><R><K><A><E><K><L><Q><R><K><F><V><S><T><W><Q><K><L><S><P><L><Q><K><C><L><A><V><G><A><A><V><L><N><I><I><L><I><A><L><F><L><V><Y...
Golgi membrane protein involved in vesicular trafficking and spindle migration.<BOP>
A6RIB9
Q6ZCX1
YSL17_ORYSJ
Protein YELLOW STRIPE LIKE 17
Oryza sativa
<M><A><E><E><A><R><G><G><Q><R><V><V><V><D><D><D><R><E><D><A><S><S><V><A><S><S><T><E><R><A><F><E><G><E><P><L><P><S><L><G><E><T><V><T><A><R><S><A><A><V><S><G><V><L><G><A><V><V><S><V><V><A><M><R><L><N><L><T><S><G><L><L><P><S><L><G><V><P><A><G><L><L><G><F><F><L><A><R><V><W><I><R><A><L><D><V><V><G><V><S><H><L><P><F><T><R><Q...
May be involved in the transport of nicotianamine-chelated metals.<BOP>
Q6ZCX1
Q8Y6U8
TPX_LISMO
Thioredoxin-dependent peroxiredoxin
Listeria
<M><T><Q><V><T><F><K><H><N><P><V><T><L><V><G><T><E><R><K><V><G><D><K><A><P><N><F><T><V><V><N><R><D><L><E><E><V><T><L><H><D><Y><D><G><K><V><R><L><I><S><V><V><P><S><I><D><T><S><V><C><S><T><Q><T><R><K><F><N><E><E><A><S><N><L><D><N><T><V><V><L><T><I><S><V><D><L><P><F><A><Q><K><K><W><C><A><A><E><G><L><P><N><A><I><T><L><S><D...
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.<BOP>
Q8Y6U8
Q3IZ05
TRMD_CERS4
tRNA [GM37] methyltransferase
Cereibacter
<M><L><K><G><A><W><Q><A><R><I><V><T><L><F><P><E><A><F><P><G><T><L><G><L><S><L><T><G><K><A><L><E><M><G><L><W><S><L><E><T><I><D><L><R><P><F><G><E><G><R><H><R><N><V><D><D><N><P><A><G><G><G><A><G><M><V><L><R><A><D><I><V><A><R><A><L><D><A><A><S><V><G><T><P><P><E><R><S><R><W><P><V><V><Y><L><S><P><R><G><K><P><F><S><Q><A><M><A...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
Q3IZ05
P41352
TBB_TETTH
Beta-tubulin
Tetrahymena
<M><R><E><I><V><H><I><Q><G><G><Q><C><G><N><Q><I><G><A><K><F><W><E><V><I><S><D><E><H><G><I><D><P><T><G><T><Y><H><G><D><S><D><L><Q><L><E><R><I><N><V><Y><Y><N><E><A><T><G><G><R><Y><V><P><R><A><I><L><M><D><L><E><P><G><T><M><D><S><V><R><A><G><P><F><G><Q><L><F><R><P><D><N><F><V><F><G><Q><T><G><A><G><N><N><W><A><K><G><H><Y><T...
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-...
P41352
Q6IQC7
TMX2B_DANRE
Thioredoxin domain-containing protein 14
Danio
<M><A><L><L><T><P><L><F><A><F><L><Y><H><L><P><Q><V><Y><K><W><L><L><K><P><Y><Y><I><A><S><L><F><M><S><I><A><F><V><M><I><R><K><M><P><G><V><C><E><H><L><S><T><Q><R><E><D><G><N><S><C><D><F><D><W><R><E><V><E><I><L><M><F><L><S><A><I><V><M><M><K><N><R><R><A><I><T><I><E><Q><H><V><G><N><I><I><L><F><C><K><V><A><N><V><I><L><F><F><R...
Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity.<BOP>
Q6IQC7
B1KNS7
TILS_SHEWM
tRNA(Ile)-lysidine synthetase
Shewanella
<M><T><E><P><S><F><N><T><S><A><L><I><E><E><S><I><K><S><A><K><I><N><V><G><A><K><L><V><L><A><Y><S><G><G><V><D><S><E><V><L><A><Q><G><L><S><L><Y><A><K><S><H><P><E><F><R><Y><L><L><V><H><V><H><H><G><L><S><R><N><A><D><A><W><V><T><H><C><Q><K><Q><A><L><D><Y><Q><L><P><I><E><V><V><Q><V><Q><V><K><T><G><P><R><L><S><I><E><A><E><A><R...
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP>
B1KNS7
P57515
TYSY_BUCAI
Thymidylate synthase
Buchnera
<M><K><Q><Y><I><K><L><I><K><K><I><I><R><V><G><N><Q><K><K><D><R><T><G><T><G><T><L><S><I><F><G><Y><N><M><K><F><D><L><K><K><G><F><P><L><L><T><T><K><K><C><H><I><A><S><I><I><Y><E><L><L><W><F><L><K><G><D><T><N><I><S><Y><L><N><E><N><K><I><S><I><W><N><N><W><A><N><E><S><G><D><V><G><P><I><Y><G><K><Q><W><R><N><W><S><T><P><E><G><H...
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracell...
P57515
C0HL49
TP1A_RANIT
Temporin-1ITa
Rana
<F><L><G><A><I><A><Q><A><L><T><S><L><L><G><K><L>
Antimicrobial peptide active against Gram-positive bacterium S.epidermidis ATCC 12228 (MIC=8 uM) and against yeast C.parapsilosis ATCC 22019 (MIC=64 uM) but not against Gram-negative bacterium E.coli ATCC 25922. Has hemolytic and cytotoxic activity.<BOP>
C0HL49
Q9I744
TSSF1_PSEAE
Type VI secretion system component TssF1
Pseudomonas
<M><N><P><R><L><L><E><Y><Y><N><Q><E><L><Q><H><I><R><E><S><A><A><E><F><A><E><E><F><P><K><I><A><G><R><L><S><L><S><G><F><E><C><A><D><P><Y><V><E><R><L><L><E><G><F><A><Y><L><T><A><R><V><Q><L><K><L><D><A><E><Y><P><T><F><T><H><N><L><L><E><I><A><Y><P><H><Y><L><A><P><T><P><S><M><T><V><V><Q><L><R><P><D><P><N><E><G><A><L><S><S><G...
Core component of the H1 type VI (H1-T6SS) secretion system that plays a role in the release of toxins targeting both eukaryotic and prokaryotic species.<BOP>
Q9I744
Q8VBT0
TMX1_MOUSE
Thioredoxin domain-containing protein 1
Mus
<M><A><H><L><G><R><L><M><V><P><L><A><A><L><V><L><L><L><W><A><V><P><G><A><H><G><R><R><N><N><V><R><V><L><T><D><E><N><W><T><S><L><L><E><G><E><W><M><I><E><F><Y><A><P><W><C><P><A><C><Q><N><L><Q><P><E><W><E><S><F><A><E><W><G><E><D><L><E><V><K><V><A><K><V><D><V><T><E><Q><T><G><L><S><G><R><F><I><I><T><A><L><P><S><I><Y><H><C><K...
May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.<BOP>
Q8VBT0
C3K7T2
UVRC_PSEFS
Excinuclease ABC subunit C
Pseudomonas
<M><T><T><P><F><D><P><S><A><F><L><S><T><C><S><G><R><P><G><V><Y><R><M><F><D><S><E><A><R><L><L><Y><V><G><K><A><K><N><L><K><N><R><L><A><S><Y><F><R><K><S><G><L><A><P><K><T><A><A><L><V><A><R><I><A><Q><V><E><T><T><I><T><A><N><E><T><E><A><L><L><L><E><Q><T><L><I><K><E><W><R><P><P><Y><N><I><L><L><R><D><D><K><S><Y><P><Y><V><F><L...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.<BOP>
C3K7T2
Q9JME7
TPC2L_MOUSE
Trafficking protein particle complex subunit 2-like protein
Mus
<M><A><V><C><I><A><V><I><A><K><E><N><Y><P><L><Y><I><R><S><T><P><T><E><S><E><L><K><F><H><Y><M><V><H><T><S><L><D><V><V><D><E><K><I><S><A><M><G><K><A><L><V><D><Q><R><E><L><Y><L><G><L><L><Y><P><T><E><D><Y><K><V><Y><G><Y><V><T><N><S><K><V><K><F><V><M><V><V><D><S><S><N><T><A><L><R><D><N><E><I><R><S><M><F><R><K><L><H><N><S><Y...
May play a role in vesicular transport from endoplasmic reticulum to Golgi.<BOP>
Q9JME7
C1DEK7
Y1984_AZOVD
Nucleoid-associated protein Avin_19840
Azotobacter
<M><M><K><G><G><M><A><G><L><M><K><Q><A><Q><L><M><Q><E><K><M><Q><K><L><Q><E><E><I><A><N><A><E><V><T><G><Q><S><G><A><G><L><V><S><V><V><M><T><G><R><H><D><V><R><R><V><T><L><D><D><S><L><M><Q><E><D><K><E><V><L><E><D><L><I><A><A><A><V><N><D><A><V><R><K><I><E><Q><N><N><Q><E><K><M><A><G><M><T><A><G><M><G><L><P><P><G><F><K><M><P...
Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.<BOP>
C1DEK7
P0DJ50
VKT31_MESMA
Delta-KTx 3.1
Mesobuthus
<M><M><N><V><I><T><V><V><G><I><I><L><S><V><V><C><T><I><S><D><A><E><G><V><D><C><T><L><P><S><D><T><G><R><C><K><A><Y><F><I><R><Y><F><Y><N><Q><K><A><G><E><C><Q><K><F><V><Y><G><G><C><E><G><N><S><N><N><F><L><T><K><S><D><C><C><K><Q><C><S><P><G><K><C>
Dual-function toxin that completely inhibits trypsin activity at a molar ratio of 1:1 (dissociation constant of 420 nM) and that inhibits mKv1.3/KCNA3 potassium channel currents with an IC(50) of 371.3 nM.<BOP>
P0DJ50
Q8TZV9
XERA_PYRFU
Tyrosine recombinase XerA
Pyrococcus
<M><R><E><K><T><L><R><S><E><V><L><E><E><F><A><T><Y><L><E><L><E><G><K><S><K><N><T><I><R><M><Y><T><Y><F><L><S><K><F><L><E><E><G><Y><S><P><T><A><R><D><A><L><R><F><L><A><K><L><R><A><K><G><Y><S><I><R><S><I><N><L><V><V><Q><A><L><K><A><Y><F><K><F><E><G><L><N><E><E><A><E><R><L><R><N><P><K><I><P><K><T><L><P><K><S><L><T><E><E><E...
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.<BOP>
Q8TZV9
A1URT5
UBIG_BARBK
3-demethylubiquinone 3-O-methyltransferase
Bartonella
<M><I><N><K><T><R><T><T><V><D><Q><S><E><I><D><H><F><S><R><I><A><A><E><W><W><N><P><Q><G><K><F><R><P><L><H><K><F><N><P><T><R><L><A><Y><I><K><E><K><I><C><L><A><F><D><R><D><P><F><S><L><A><P><F><A><G><L><K><I><L><D><I><G><C><G><G><G><L><L><C><E><P><M><V><R><L><G><A><T><V><I><G><A><D><A><A><Q><N><N><I><E><V><A><K><I><H><A><T...
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.<BOP>
A1URT5
Q2M2T2
TKTI1_BOVIN
Uncharacterized protein C19orf71 homolog
Bos
<M><Q><T><L><R><R><Q><A><A><W><P><C><V><P><R><G><T><L><E><V><D><F><P><P><P><L><Y><S><D><D><Y><L><S><Q><E><G><P><R><W><T><P><A><I><K><Q><A><T><R><W><K><Y><T><P><M><G><R><D><A><A><G><Q><L><W><Y><T><G><L><T><N><S><D><S><R><E><A><W><Y><T><L><P><R><A><P><D><S><P><Y><R><E><A><Y><A><R><W><H><G><C><Y><G><H><R><E><R><S><L><P><S...
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating. Located at the center of the tektin bundle where may function to recruit tektins or stabilize the bundle.<BOP>
Q2M2T2
A9HZS2
UBID_BORPD
Polyprenyl p-hydroxybenzoate decarboxylase
Bordetella
<M><K><Y><R><D><L><R><D><F><L><Q><Q><L><E><L><R><G><E><L><K><R><I><A><T><P><V><S><T><H><L><E><M><T><E><I><A><D><R><V><L><R><A><Q><G><P><A><L><L><F><E><H><A><V><H><N><G><A><R><A><A><M><P><V><L><A><N><L><F><G><T><P><R><R><V><A><W><G><M><G><A><D><E><V><S><A><L><R><D><T><G><E><L><L><A><S><L><R><E><P><E><A><P><R><G><L><R><D...
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.<BOP>
A9HZS2
Q1CV84
UREE_HELPH
Urease accessory protein UreE
Helicobacter
<M><I><I><E><R><L><V><G><N><L><R><D><L><N><P><L><D><F><N><V><D><H><V><D><L><E><W><F><E><T><R><K><K><I><A><R><F><K><T><R><Q><G><K><D><I><A><I><R><L><K><D><A><P><K><L><G><L><S><Q><G><D><I><L><F><K><E><E><K><E><I><I><A><V><N><I><L><D><S><E><V><I><H><I><Q><A><K><S><V><A><E><V><A><K><I><C><Y><E><I><G><N><R><H><A><A><L><Y><Y...
Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.<BOP>
Q1CV84
Q500M2
XPT_PSEU2
Xanthine phosphoribosyltransferase
Pseudomonas syringae
<M><E><A><L><H><K><K><I><R><E><E><G><I><V><L><S><D><Q><V><L><K><V><D><A><F><L><N><H><Q><I><D><P><A><L><M><K><E><I><G><D><E><F><A><R><L><F><A><D><A><G><V><T><K><I><V><T><I><E><A><S><G><I><A><P><A><V><M><A><G><L><N><M><G><V><P><V><I><F><A><R><K><H><Q><S><L><T><L><T><E><N><L><L><T><A><S><V><Y><S><F><T><K><Q><V><E><S><T><V...
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP>
Q500M2
Q13BD7
UREG_RHOPS
Urease accessory protein UreG
Rhodopseudomonas
<M><S><T><H><H><G><P><L><R><V><G><I><G><G><P><V><G><S><G><K><T><A><L><M><D><L><L><C><K><S><M><R><E><R><Y><D><I><A><A><I><T><N><D><I><Y><T><K><W><D><A><E><F><L><V><R><S><G><S><L><T><P><D><R><I><A><G><V><E><T><G><G><C><P><H><T><A><I><R><E><D><A><S><M><N><L><A><A><V><A><E><M><R><S><K><F><P><G><L><D><L><V><L><I><E><S><G><G...
Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.<BOP>
Q13BD7
Q6L1R1
TBP_PICTO
TATA-box factor
Picrophilus
<M><S><E><M><E><K><I><T><I><E><N><I><V><A><S><T><S><L><A><E><H><L><D><L><S><K><I><A><L><A><L><E><G><S><E><Y><E><P><E><Q><F><P><G><L><I><Y><R><L><Q><E><P><K><T><A><V><L><I><F><R><S><G><K><V><N><C><T><G><A><K><N><L><D><D><V><K><K><T><I><D><I><I><I><D><K><L><K><K><A><D><I><E><V><Y><D><N><P><D><I><I><V><Q><N><I><V><A><V><Y...
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.<BOP>
Q6L1R1
P49339
WNT11_CHICK
Protein Wnt-11
Gallus
<M><K><P><S><P><Q><F><F><L><A><A><F><L><S><L><I><L><Q><T><G><I><C><Y><G><I><K><W><I><A><L><S><K><T><P><S><S><L><A><L><N><Q><T><Q><H><C><K><Q><L><E><G><L><V><V><S><Q><V><Q><L><C><R><S><N><L><E><L><M><Q><T><I><I><Q><A><A><R><E><V><I><K><T><C><R><K><T><F><S><D><M><R><W><N><C><S><S><I><E><L><A><P><N><Y><L><L><D><L><E><R><G...
Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters.<BOP>
P49339
O31562
YFIT_BACSU
Putative metal-dependent hydrolase YfiT
Bacillus
<M><T><S><V><N><L><S><Y><P><I><G><E><Y><K><P><R><E><S><I><S><K><E><Q><K><D><K><W><I><Q><V><L><E><E><V><P><A><K><L><K><Q><A><V><E><V><M><T><D><S><Q><L><D><T><P><Y><R><D><G><G><W><T><V><R><Q><V><V><H><H><L><A><D><S><H><M><N><S><Y><I><R><F><K><L><S><L><T><E><E><T><P><A><I><R><P><Y><D><E><K><A><W><S><E><L><K><D><S><K><T><A...
Possible metal-dependent hydrolase.<BOP>
O31562
P47683
TRMD_MYCGE
tRNA [GM37] methyltransferase
Mycoplasma
<M><K><I><T><V><L><T><L><F><E><N><T><I><W><P><Y><L><N><S><S><I><M><L><Q><A><Q><K><A><N><L><V><Q><F><E><V><V><N><W><R><N><F><C><N><D><K><H><K><T><V><D><D><M><A><Y><G><G><G><S><G><M><V><L><K><A><E><P><I><I><N><C><L><N><F><Y><K><A><P><N><S><H><V><V><L><L><S><P><E><G><E><Q><F><S><Q><N><C><A><K><K><L><T><K><Y><E><H><L><I><L...
Specifically methylates guanosine-37 in various tRNAs.<BOP>
P47683
A7X1M7
XERC_STAA1
Tyrosine recombinase XerC
Staphylococcus
<M><N><H><I><Q><E><A><F><L><N><T><L><K><V><E><R><N><F><S><E><H><T><L><K><S><Y><Q><D><D><L><I><Q><F><N><Q><F><L><E><Q><E><H><L><Q><L><K><T><F><E><Y><R><D><A><R><N><Y><L><S><Y><L><Y><S><N><H><L><K><R><T><S><V><S><R><K><I><S><T><L><R><T><F><Y><E><Y><W><M><T><L><D><E><N><I><I><N><P><F><V><Q><L><V><H><P><K><K><E><K><Y><L><P...
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plas...
A7X1M7
X1WER2
UBA5_DANRE
UFM1-activating enzyme
Danio
<M><A><T><V><E><E><L><K><L><R><I><R><E><L><E><N><E><L><I><K><S><K><Q><K><Q><S><D><A><E><H><N><I><R><P><K><I><E><Q><M><S><A><E><V><V><D><S><N><P><Y><S><R><L><M><A><L><K><R><M><G><I><V><Q><D><Y><E><K><I><R><S><F><A><V><A><V><V><G><V><G><G><V><G><S><V><T><A><E><M><L><T><R><C><G><I><G><K><L><L><L><F><D><Y><D><K><V><E><L><A...
E1-like enzyme which specifically catalyzes the first step in ufmylation. Activates ufm1 by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ufm1-E1 thioester and free AMP. Activates ufm1 via a trans-binding mechanis...
X1WER2
Q6QDC9
TBB_ZYMTR
Beta-tubulin
Zymoseptoria
<M><R><E><I><V><H><L><Q><T><G><Q><C><G><N><Q><I><G><A><A><F><W><Q><T><I><S><G><E><H><G><L><D><G><S><G><V><Y><N><G><T><S><D><L><Q><L><E><R><M><N><V><Y><F><N><E><A><S><G><N><K><Y><V><P><R><A><V><L><V><D><L><E><P><G><T><M><D><A><V><R><A><G><P><F><G><Q><L><F><R><P><D><N><F><V><F><G><Q><S><G><A><G><N><N><W><A><K><G><H><Y><T...
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-...
Q6QDC9
B5KL33
VKT2_TROCA
Kunitz-type serine protease inhibitor carinatin-2
Tropidechis
<M><S><S><G><G><L><L><L><L><L><G><L><L><T><L><W><E><I><L><T><P><V><S><S><K><D><H><P><E><F><C><E><L><P><A><D><S><G><P><C><R><G><I><L><H><A><F><Y><Y><H><P><V><H><R><T><C><L><E><F><I><Y><G><G><C><Y><G><N><A><N><N><F><K><T><I><D><E><C><K><R><T><C><A><A>
Serine protease inhibitor.<BOP>
B5KL33
B4R1Q1
TOTZ_DROSI
Protein Turandot Z
Sophophora
<M><Y><F><A><I><R><L><S><F><V><L><A><V><L><F><C><L><T><G><N><G><S><A><R><M><L><D><A><D><R><N><R><L><Q><Q><L><Q><I><R><S><Q><Q><S><A><D><A><N><T><Q><V><D><I><A><Y><E><V><I><G><I><Y><D><K><Y><K><G><Q><G><G><S><N><V><L><R><E><A><Q><L><N><S><Q><V><N><D><F><K><R><K><T><M><V><I><D><G><V><P><A><Q><G><G><V><W><G><I><L><G><A><I...
A humoral factor that may play a role in stress tolerance.<BOP>
B4R1Q1
P39849
XYLB_PSEPU
Benzyl alcohol dehydrogenase
Pseudomonas
<M><E><I><K><A><A><I><V><R><Q><K><N><G><P><F><L><L><E><H><V><A><L><N><E><P><A><E><D><Q><V><L><V><R><L><V><A><T><G><L><C><H><T><D><L><V><C><R><D><Q><H><Y><P><V><P><L><P><M><V><F><G><H><E><G><A><G><V><V><E><R><V><G><S><A><V><K><K><V><Q><P><G><D><H><V><V><L><T><F><Y><T><C><G><S><C><D><A><C><L><S><G><D><P><T><S><C><A><N><S...
Oxidizes primary alcohols with an aromatic or cyclohex-1-ene ring. It is highly specific for benzyl alcohol.<BOP>
P39849
C1A4H0
UVRB_GEMAT
Excinuclease ABC subunit B
Gemmatimonas
<M><T><A><P><F><R><L><H><A><P><F><A><P><A><G><D><Q><P><R><A><I><T><E><L><S><S><G><L><H><R><G><D><R><I><Q><T><L><L><G><V><T><G><S><G><K><T><M><T><M><A><N><V><I><A><D><W><G><R><P><T><L><V><L><S><H><N><K><T><L><A><A><Q><L><Y><G><E><L><K><S><F><F><P><N><N><A><V><E><Y><F><I><S><Y><Y><D><Y><Y><Q><P><E><A><Y><V><P><S><S><D><T...
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP bindi...
C1A4H0
P91800
TCTP_SCHJA
Translationally-controlled tumor protein homolog
Schistosoma
<M><R><V><F><K><D><A><I><S><G><D><E><M><F><S><D><S><H><S><P><Q><L><I><N><D><V><V><Y><E><V><D><A><N><F><I><T><V><S><N><G><L><D><S><K><L><I><A><A><N><P><S><G><E><E><G><Q><E><E><V><S><D><S><T><E><R><V><I><D><L><V><H><A><S><R><L><V><S><T><S><F><D><K><K><S><Y><R><A><Y><L><K><G><Y><L><K><A><I><K><E><R><L><Q><K><E><N><P><E><R...
Involved in calcium binding and microtubule stabilization.<BOP>
P91800
P32610
VATD_YEAST
Vacuolar proton pump subunit D
Saccharomyces
<M><S><G><N><R><E><Q><V><F><P><T><R><M><T><L><G><L><M><K><T><K><L><K><G><A><N><Q><G><Y><S><L><L><K><R><K><S><E><A><L><T><K><R><F><R><D><I><T><K><R><I><D><D><A><K><Q><K><M><G><R><V><M><Q><T><A><A><F><S><L><A><E><V><S><Y><A><T><G><E><N><I><G><Y><Q><V><Q><E><S><V><S><T><A><R><F><K><V><R><A><R><Q><E><N><V><S><G><V><Y><L><S...
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons . V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments .<BOP>
P32610
Q9CR76
TM186_MOUSE
Transmembrane protein 186
Mus
<M><A><F><L><L><R><V><V><P><R><L><Q><G><P><T><A><W><R><R><P><L><Q><G><L><W><C><C><S><G><Q><G><D><S><K><R><W><V><G><S><R><S><P><H><S><R><E><K><S><P><G><T><E><T><E><T><F><H><T><I><Y><R><F><R><A><I><R><A><I><G><F><L><S><R><L><K><L><A><Q><T><A><V><T><V><V><A><L><P><P><G><F><Y><C><Y><S><Q><G><L><M><T><L><S><S><L><C><L><L><G...
As part of the MCIA complex, required for efficient assembly of the mitochondrial complex I.<BOP>
Q9CR76
Q9FTU1
YSL1_ORYSJ
Protein YELLOW STRIPE LIKE 1
Oryza sativa
<M><A><D><P><A><G><A><G><G><E><Q><E><A><P><S><V><E><A><A><F><A><G><Q><P><P><P><P><W><W><Q><Q><V><T><V><R><A><V><A><V><S><V><V><L><G><T><L><F><S><F><M><A><M><R><T><G><L><T><A><G><F><V><P><S><F><N><M><S><A><S><L><L><S><F><F><I><I><K><S><W><T><R><L><M><A><R><C><G><V><A><S><Q><P><F><T><R><Q><E><N><V><V><V><Q><T><C><V><I><S...
May be involved in the transport of nicotianamine-chelated metals.<BOP>
Q9FTU1
Q554C5
WRKY1_DICDI
WRKY domain-containing protein 1
Dictyostelium
<M><G><A><Q><Y><S><T><E><L><N><K><Y><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><H><T><I><S><G><N><E><N><L><N><N><N><N><N><N><N><N><N><N><N><N><Y><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><N><K><N><N><G><N><S><N><S><N><S><N><N><N><N><N><N><N><G><I><N><K...
Probable transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element.<BOP>
Q554C5
Q6AUG0
U2AFB_ORYSJ
Zinc finger CCCH domain-containing protein 38
Oryza sativa
<M><A><E><H><L><A><S><I><F><G><T><E><K><D><R><V><N><C><P><F><Y><F><K><I><G><A><C><R><H><G><D><R><C><S><R><L><H><N><R><P><T><V><S><P><T><I><V><L><A><N><M><Y><Q><R><P><D><M><I><T><P><G><V><D><A><Q><G><Q><P><I><D><P><E><K><M><Q><E><H><F><E><D><F><Y><E><D><I><Y><E><E><L><S><K><F><G><E><V><E><T><L><N><V><C><D><N><L><A><D><H...
Necessary for the splicing of pre-mRNA.<BOP>
Q6AUG0
Q9VWB9
THADA_DROME
Thyroid adenoma-associated protein homolog
Sophophora
<M><N><D><L><N><L><R><V><A><A><L><K><V><C><A><H><P><K><R><F><A><E><L><R><D><A><L><V><P><L><P><N><T><W><I><A><A><P><H><D><F><V><L><Q><F><A><A><A><K><S><S><A><E><Q><V><Q><V><V><K><D><V><F><Y><G><E><Q><A><Q><D><H><E><D><V><A><H><F><L><A><D><L><L><L><A><S><P><L><K><H><A><V><R><N><Q><L><T><K><L><F><S><D><N><A><L><A><K><Q><N...
Plays a key role in energy homeostasis by regulating the balance between energy storage and heat production. Functions by negatively regulating Ca(2+) signaling pathways that are involved in heat production and maintaining correct lipid storage in the fat body. Regulates Ca(2+) signaling pathways by reducing the activi...
Q9VWB9
P9WFZ0
TRMI_MYCTO
tRNA(m1A58)-methyltransferase
Mycobacterium tuberculosis complex
<M><S><A><T><G><P><F><S><I><G><E><R><V><Q><L><T><D><A><K><G><R><R><Y><T><M><S><L><T><P><G><A><E><F><H><T><H><R><G><S><I><A><H><D><A><V><I><G><L><E><Q><G><S><V><V><K><S><S><N><G><A><L><F><L><V><L><R><P><L><L><V><D><Y><V><M><S><M><P><R><G><P><Q><V><I><Y><P><K><D><A><A><Q><I><V><H><E><G><D><I><F><P><G><A><R><V><L><E><A><G...
Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.<BOP>
P9WFZ0
Q70Y02
YCF3_AMBTC
Photosystem I assembly protein Ycf3
Amborella
<M><P><R><S><R><I><N><G><N><F><I><D><K><T><S><S><I><V><A><N><I><L><L><R><I><I><P><T><T><S><G><E><K><E><A><F><T><Y><Y><R><D><G><M><S><A><Q><S><E><G><N><Y><A><E><A><L><Q><N><Y><Y><E><A><T><R><P><E><I><D><P><Y><D><R><S><Y><I><L><Y><N><I><G><L><I><H><T><S><N><G><E><H><T><K><A><L><E><Y><Y><F><R><A><L><E><R><N><P><F><L><P><Q...
Essential for the assembly of the photosystem I (PSI) complex. May act as a chaperone-like factor to guide the assembly of the PSI subunits.<BOP>
Q70Y02
I1S2K3
XYNA_GIBZE
1,4-beta-D-xylan xylanohydrolase A
Fusarium
<M><V><S><F><K><S><L><L><V><A><V><S><A><L><T><G><A><L><A><R><P><F><D><F><L><D><E><R><D><D><G><N><A><T><S><V><L><E><A><R><Q><V><T><G><N><S><E><G><Y><H><N><G><Y><F><Y><S><W><W><S><D><G><G><G><Y><A><Q><Y><R><M><G><E><G><S><H><Y><Q><V><D><W><R><N><T><G><N><F><V><G><G><K><G><W><N><P><G><T><G><R><T><I><N><Y><G><G><S><F><N><P...
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Plays an important role in causing fusarium head blight (FHB) on cereal crops.<BOP>
I1S2K3
Q46GQ7
TAL_PROMT
Transaldolase
Prochlorococcus
<M><E><S><L><L><S><Q><L><S><S><M><T><V><V><V><A><D><T><G><D><L><E><A><I><K><K><Y><H><P><R><D><A><T><T><N><P><S><L><I><L><A><A><A><Q><M><P><A><Y><Q><S><L><I><D><Q><A><L><T><T><S><R><E><M><L><G><T><S><A><A><K><A><D><V><V><K><E><A><L><D><E><L><C><V><V><F><G><K><E><I><L><K><L><I><P><G><R><V><S><T><E><V><D><A><R><L><S><F><D...
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.<BOP>
Q46GQ7
O59947
TRI5_STACH
Sesquiterpene cyclase
Stachybotrys
<M><E><A><F><P><T><E><Y><F><L><G><T><A><V><R><L><L><E><N><V><K><Y><R><D><S><N><Y><T><R><E><E><R><V><E><N><L><Q><Y><A><Y><N><K><A><A><A><H><F><A><Q><E><R><Q><Q><Q><I><L><K><V><S><P><K><R><L><E><A><S><L><R><T><I><V><G><M><V><V><Y><S><W><A><K><V><S><K><E><L><M><A><D><L><S><I><H><Y><T><Y><T><L><I><L><D><D><S><E><D><D><P><H...
TS is a member of the terpene cyclase group of enzymes. It catalyzes the isomerization and cyclization of farnesyl pyro-phosphate to form trichodiene, the first cyclic intermediate in the biosynthetic pathway for trichothecenes. It serves to branch trichothecene biosynthesis from the isoprenoid pathway.<BOP>
O59947
A2SDR5
URED_METPP
Urease accessory protein UreD
Methylibium
<M><A><W><L><G><S><L><D><L><H><Y><R><P><D><P><D><A><P><A><A><A><L><P><R><T><I><G><R><G><V><H><S><G><P><L><R><V><L><Q><S><L><Y><P><E><G><P><G><I><C><H><H><V><L><V><H><P><P><G><G><I><V><G><G><D><E><L><A><L><T><A><Q><V><D><T><G><A><H><A><L><L><T><T><P><G><A><T><R><F><Y><R><S><G><G><D><A><A><L><Q><T><L><T><A><R><V><A><D><G...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
A2SDR5
Q9D3D0
TTPAL_MOUSE
Alpha-tocopherol transfer protein-like
Mus
<M><S><E><E><S><D><S><L><R><T><S><P><S><V><A><S><L><S><E><N><E><L><P><L><P><P><P><D><P><P><G><Y><V><C><S><L><T><E><D><L><V><T><K><A><R><E><E><L><Q><E><K><P><E><W><R><L><R><D><V><Q><A><L><R><D><M><V><R><K><E><Y><P><Y><L><S><T><S><L><D><D><A><F><L><L><R><F><L><R><A><R><K><F><D><Y><D><R><A><L><Q><L><L><V><N><Y><H><G><C><R...
May act as a protein that binds a hydrophobic ligand.<BOP>
Q9D3D0
A9WDP2
YIDD_CHLAA
Putative membrane protein insertion efficiency factor
Chloroflexus
<M><L><R><W><L><L><L><K><L><I><R><F><Y><Q><V><A><I><S><P><W><T><P><P><S><C><I><Y><T><P><T><C><S><H><Y><G><Y><E><A><I><K><K><Y><G><A><L><R><G><G><W><M><T><V><K><R><I><A><R><C><H><P><F><A><R><G><G><Y><D><P><V><P>
Could be involved in insertion of integral membrane proteins into the membrane.<BOP>
A9WDP2
Q1H4G9
TSAC_METFK
tRNA threonylcarbamoyladenosine biosynthesis protein TsaC
Methylobacillus
<M><R><A><R><A><L><Q><H><F><L><R><S><G><G><V><I><A><Y><P><T><E><S><C><F><G><L><G><C><D><P><T><N><H><R><A><L><K><R><L><L><R><I><K><G><R><P><Q><R><K><G><L><I><V><I><A><Q><H><F><S><Q><L><Q><K><L><I><A><P><V><T><P><E><Q><K><Q><R><M><F><T><R><W><P><G><P><H><T><W><L><V><P><A><S><R><R><C><P><A><L><L><R><G><R><H><T><S><L><A><V...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.<BOP>
Q1H4G9
Q9KA80
TRUB_HALH5
tRNA-uridine isomerase
Halalkalibacterium (ex Joshi et al. 2022)
<M><D><M><T><G><I><L><P><L><A><K><P><R><G><M><T><S><H><D><C><V><A><K><L><R><R><L><L><K><T><K><K><V><G><H><T><G><T><L><D><P><D><V><Y><G><V><L><P><V><C><I><G><H><A><T><K><V><A><Q><Y><M><S><D><Y><P><K><A><Y><E><G><E><V><T><V><G><F><S><T><T><T><E><D><R><S><G><D><T><V><E><T><K><T><I><Q><Q><P><F><V><E><A><V><V><D><Q><V><L><A...
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.<BOP>
Q9KA80
Q8SSC5
UGPA1_ENCCU
UDP-glucose pyrophosphorylase
Encephalitozoon
<M><Q><E><S><R><S><K><E><S><T><L><S><G><D><E><D><K><D><V><H><R><F><L><D><E><F><D><D><K><C><T><C><K><L><L><K><E><M><K><E><T><L><E><G><L><K><K><S><H><P><N><P><T><N><L><D><E><F><Y><R><L><F><E><R><Y><L><R><T><R><H><E><K><I><V><W><E><K><I><R><S><P><K><D><R><I><V><Q><Y><N><E><I><P><E><P><T><E><K><S><K><E><L><L><R><K><L><A><I...
Plays a central role as a glucosyl donor in cellular metabolic pathways.<BOP>
Q8SSC5
Q664P8
TAUB_YERPS
Taurine import ATP-binding protein TauB
Yersinia
<M><L><N><V><S><G><L><W><A><E><Y><Q><G><K><P><A><L><Q><D><V><S><L><Q><I><A><S><G><Q><L><V><V><V><L><G><P><S><G><C><G><K><T><T><L><L><N><L><I><A><G><F><M><T><P><S><A><G><V><I><T><L><D><N><I><P><V><S><G><P><S><A><E><R><G><V><V><F><Q><N><E><G><L><L><P><W><R><D><V><V><S><N><V><E><F><G><L><Q><L><A><G><M><S><K><E><Q><R><R><V...
Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system.<BOP>
Q664P8
C4XNJ6
YIDC_SOLM1
Membrane protein YidC
Solidesulfovibrio
<M><E><N><K><R><V><I><L><A><V><A><L><S><L><A><V><L><V><G><W><N><F><L><F><P><P><A><K><Q><A><P><K><P><D><A><A><V><S><Q><Q><D><A><P><A><Q><S><S><P><A><A><P><A><A><K><A><E><T><L><A><A><F><A><P><T><P><G><K><R><I><T><I><D><T><P><L><Y><T><A><V><L><N><S><T><G><G><V><L><E><Q><F><A><L><K><N><Y><R><E><T><I><K><P><D><S><P><L><V><N...
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning memb...
C4XNJ6
A7FT29
XPT2_CLOB1
Xanthine phosphoribosyltransferase 2
Clostridium
<M><K><L><L><E><D><K><I><L><K><E><G><I><L><L><E><G><N><I><L><K><V><D><S><F><L><N><H><Q><M><D><V><K><L><F><N><E><I><G><K><E><F><K><R><R><F><E><G><C><S><I><N><K><I><L><T><I><E><A><S><G><I><G><I><A><T><I><V><S><Q><Y><F><D><F><C><P><V><V><F><A><K><K><V><D><A><A><N><M><D><K><D><T><Y><E><S><K><V><H><S><F><T><K><N><K><T><Y><N...
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.<BOP>
A7FT29
A1AZC8
YQGF_PARDP
Putative pre-16S rRNA nuclease
Paracoccus
<M><I><C><E><N><V><E><T><F><A><E><A><L><P><R><T><G><A><V><A><G><L><D><L><G><T><K><T><I><G><V><A><V><S><D><G><L><R><G><V><A><S><P><L><T><V><I><R><R><T><K><F><T><A><D><A><Q><A><L><L><K><I><V><Q><D><R><A><L><V><G><L><V><L><G><L><P><R><N><M><D><G><S><E><G><P><R><A><Q><S><T><R><A><F><A><R><N><L><E><R><L><T><P><L><P><I><T><F...
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.<BOP>
A1AZC8
A3QFX7
TIG_SHELP
PPIase
Shewanella
<M><Q><V><S><V><E><T><T><Q><G><L><E><R><R><L><T><I><S><V><P><A><E><Q><I><E><K><A><V><S><D><S><L><K><N><E><A><K><R><A><R><I><P><G><F><R><P><G><K><V><P><V><S><V><I><N><K><R><Y><G><K><A><I><R><Q><E><I><T><G><E><V><M><Q><R><N><F><I><E><A><I><I><A><E><K><L><N><P><A><G><A><P><T><F><V><P><G><E><T><D><A><E><N><F><Q><F><V><A><T...
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.<BOP>
A3QFX7
Q62590
TSHB_PHOSU
Thyrotropin beta chain
Phodopus
<Y><C><L><T><I><N><T><T><I><C><A><G><Y><C><M><T><R><D><I><N><G><K><L><F><L><P><K><S><A><L><S><Q><D><V><C><T><Y><R><D><F><T><Y><R><T><V><E><I><P><G><C><P><H><H><V><A><P><Y><F><S><Y><P><V><A><M><S><C><K><C><G><K><C><N><T><D><Y><S><D><C><I><H><E><A><V><K><T><N><Y><C><T><K><P><Q><T><F><Y><L><G><G><F><S><V>
Indispensable for the control of thyroid structure and metabolism.<BOP>
Q62590
A6VTV5
URED_MARMS
Urease accessory protein UreD
Marinomonas
<M><N><N><K><H><N><L><A><L><A><E><Q><Y><D><Q><K><P><L><I><K><T><S><M><L><P><E><V><G><A><S><Q><W><H><A><F><L><T><L><G><F><S><K><T><A><R><G><T><V><L><K><T><S><D><H><K><G><P><L><Y><V><Q><K><P><F><Y><P><E><G><R><D><T><A><H><I><Y><L><L><H><P><P><G><G><L><V><S><G><D><R><L><T><I><T><A><N><L><A><E><N><T><H><V><L><I><T><T><P><G...
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.<BOP>
A6VTV5
B7UHL4
XNI_ECO27
Flap endonuclease Xni
Escherichia
<M><A><V><H><L><L><I><V><D><A><L><N><L><I><R><R><I><H><A><V><Q><G><S><P><C><V><E><T><C><Q><H><A><L><D><Q><L><I><M><H><S><Q><P><T><H><A><V><A><V><F><D><D><E><N><R><S><S><G><W><R><H><Q><R><L><P><D><Y><K><A><G><R><P><P><M><P><E><E><L><H><D><E><M><P><A><L><R><A><A><F><E><Q><R><G><V><P><C><W><S><A><S><G><N><E><A><D><D><L><A...
Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.<BOP>
B7UHL4
Q98CN6
TRPA_RHILO
Tryptophan synthase alpha chain
Mesorhizobium
<M><T><T><R><I><D><R><R><M><A><K><L><K><T><E><G><R><P><A><L><V><T><Y><F><M><G><G><D><P><D><Y><D><T><S><L><S><I><M><K><A><L><P><G><A><G><S><D><I><I><E><L><G><M><P><F><S><D><P><M><A><D><G><P><A><I><Q><A><A><G><L><R><A><L><K><G><G><Q><T><L><V><K><T><L><K><M><A><S><E><F><R><A><G><D><N><E><T><P><I><V><L><M><G><Y><Y><N><P><I...
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.<BOP>
Q98CN6
Q9XTQ6
TBH1_CAEEL
Tyramine beta-hydroxylase
Caenorhabditis
<M><E><P><T><A><S><Q><G><I><Q><Y><L><R><G><G><V><E><W><I><L><K><L><L><N><L><H><I><L><N><V><K><H><E><N><K><P><L><L><F><R><L><I><D><L><K><V><Y><I><P><S><S><V><S><T><V><R><W><S><S><G><A><S><S><Y><V><I><L><G><E><Y><R><K><M><R><S><A><V><A><L><L><F><L><L><V><A><Y><C><G><G><V><V><H><A><G><E><I><V><A><E><L><Y><H><T><N><V><T><V...
Required for the conversion of tyramine to octopamine, a precursor of octapamine but probably itself a neurotransmitter . Involved in the regulation of egg laying, which is inhibited by tyramine . Due to its involvement in octopamine biosynthesis, also required for crtc-1-dependent regulation of AMPK-mediated longevity...
Q9XTQ6
A8FHJ2
TPIS_BACP2
Triose-phosphate isomerase
Bacillus
<M><R><K><P><I><I><A><G><N><W><K><M><N><K><T><L><G><E><A><V><S><F><V><E><E><V><K><S><S><I><P><Y><P><D><K><V><E><A><I><V><C><A><P><A><L><F><L><E><K><L><N><S><L><S><N><G><T><D><L><K><I><G><A><Q><N><M><H><F><E><E><N><G><A><F><T><G><E><I><S><P><A><A><L><K><D><L><G><I><G><Y><S><V><I><G><H><S><E><R><R><E><F><F><A><E><T><D><E...
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).<BOP>
A8FHJ2
A0A063C1W0
USTZ_USTVR
Ustilaginoidins biosynthesis cluster protein Z
Ustilaginoidea
<M><A><S><H><H><Q><L><L><C><L><N><I><L><G><F><R><K><P><G><I><S><T><E><D><Y><R><N><Y><M><V><N><V><H><A><P><L><V><A><G><L><M><E><K><Y><G><F><L><H><F><T><M><S><H><A><S><E><Q><S><P><Q><L><M><D><Q><L><Y><D><A><Q><F><A><N><T><A><S><Y><D><C><C><V><Q><I><V><F><P><S><I><E><C><F><V><N><M><K><A><D><P><Y><F><K><Q><T><V><G><P><D><H...
Dehydratase; part of the gene cluster that mediates the biosynthesis of ustilaginoidins, dimeric gamma-naphthopyrones isolated from different fungal species . The first step in the biosynthesis of ustilaginoidins is the production of gamma-naphthopyrone precursor YWA1 by the non-reducing polyketide synthase ustP, via c...
A0A063C1W0
P0AAA7
WZXE_ECOLI
Lipid III flippase
Escherichia
<M><S><L><A><K><A><S><L><W><T><A><A><S><T><L><V><K><I><G><A><G><L><L><V><G><K><L><L><A><V><S><F><G><P><A><G><L><G><L><A><A><N><F><R><Q><L><I><T><V><L><G><V><L><A><G><A><G><I><F><N><G><V><T><K><Y><V><A><Q><Y><H><D><N><P><Q><Q><L><R><R><V><V><G><T><S><S><A><M><V><L><G><F><S><T><L><M><A><L><V><F><V><L><A><A><A><P><I><S><Q...
Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA). Required for the assembly of the phosphoglyceride-linked form of ECA (ECA(PG)) and the water-soluble cyclic form of...
P0AAA7
Q0JBY9
TR120_ORYSJ
Trafficking protein particle complex II-specific subunit 120 homolog
Oryza sativa
<M><E><P><G><V><S><I><E><S><G><S><A><I><R><V><A><V><L><P><V><G><G><P><I><S><P><A><R><L><R><D><Y><A><A><L><V><A><R><H><A><R><V><D><L><A><S><L><R><P><Y><Y><S><E><H><Q><K><S><P><F><A><H><Q><P><W><G><G><G><C><L><R><L><K><F><V><L><G><G><C><V><P><S><P><W><E><D><F><Q><S><S><R><K><V><L><A><V><V><G><I><C><H><L><P><S><S><P><D><L...
Specific subunit of the TRAPP II complex, a highly conserved vesicle tethering complex that is required for the proper transport of proteins in post-Golgi trafficking pathways to the growing cell plate in mitotic active cells.<BOP>
Q0JBY9
O34294
THIE_RHIEC
Thiamine-phosphate pyrophosphorylase
Rhizobium
<M><R><L><D><P><F><Y><L><I><V><D><S><A><D><W><V><E><R><L><V><P><L><G><V><K><L><V><Q><L><R><I><K><D><R><P><E><P><V><L><R><E><E><I><R><R><A><K><A><A><C><A><A><A><A><C><Q><L><I><I><N><D><Y><W><R><L><A><I><D><E><G><C><D><F><I><H><L><G><Q><E><D><L><M><A><A><D><L><A><A><I><R><R><A><G><L><K><L><G><L><S><T><H><D><P><S><E><L><E...
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).<BOP>
O34294
Q6FYQ5
TILS_BARQU
tRNA(Ile)-lysidine synthetase
Bartonella
<M><C><V><K><L><A><G><N><L><F><K><T><S><D><F><I><Q><C><R><K><V><I><L><A><V><S><G><G><S><D><S><L><A><L><L><F><L><V><K><D><H><L><K><T><F><S><I><P><T><E><I><I><V><V><T><V><D><H><Q><L><R><R><E><S><A><C><E><A><E><S><V><A><E><I><C><R><A><H><H><I><Q><H><V><I><V><R><W><E><G><K><K><P><K><T><H><I><I><S><S><A><R><T><V><R><Y><N><L...
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.<BOP>
Q6FYQ5
A8H5P7
TOLB_SHEPA
Tol-Pal system protein TolB
Shewanella
<M><K><N><L><G><K><W><L><L><T><S><L><L><I><C><S><M><P><V><K><A><A><L><D><I><I><I><T><E><G><V><D><A><A><R><P><I><A><V><I><P><F><V><W><Q><G><T><G><P><M><P><S><Q><I><S><D><V><V><M><S><D><L><A><R><S><G><T><F><S><P><A><D><E><L><S><L><P><Q><R><G><I><S><T><L><A><Q><F><N><A><S><A><W><M><A><Q><P><A><E><A><V><V><M><G><S><I><K><P...
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.<BOP>
A8H5P7
Q944T2
TCTP_SOYBN
Translationally-controlled tumor protein homolog
Glycine subgen. Soja
<M><L><V><Y><Q><D><L><L><T><G><D><E><L><L><S><D><S><F><R><Y><K><E><I><E><N><G><M><L><W><E><V><E><G><K><W><V><V><K><G><A><V><D><V><D><I><G><A><N><P><S><A><E><G><G><G><E><D><E><G><V><D><D><A><A><V><K><V><V><D><I><V><D><T><F><R><L><Q><E><Q><P><A><F><D><K><K><Q><F><V><T><F><M><K><R><F><I><K><N><L><T><P><K><L><D><A><E><Q><Q...
Involved in calcium binding and microtubule stabilization.<BOP>
Q944T2
A6VTV9
UREE_MARMS
Urease accessory protein UreE
Marinomonas
<M><L><D><I><Y><E><R><L><G><T><H><C><H><D><P><V><Y><T><T><V><T><L><T><H><E><Q><R><D><R><G><R><L><K><L><V><G><E><N><N><E><E><V><R><V><F><L><E><R><G><K><P><L><L><V><G><E><F><L><K><S><E><C><G><K><I><V><Q><V><A><G><A><V><E><D><V><A><H><A><S><C><E><D><W><E><A><F><S><K><A><C><Y><H><L><G><N><R><H><T><K><I><Q><I><G><E><R><W><L...
Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly.<BOP>
A6VTV9
Q9PFT8
TTCA_XYLFA
tRNA 2-thiocytidine biosynthesis protein TtcA
Xylella
<M><D><A><T><F><P><P><Q><R><N><I><T><A><R><P><A><P><D><R><I><R><R><E><Q><C><K><L><A><K><R><L><R><R><Q><V><G><Q><A><I><A><D><F><G><M><I><E><A><N><D><K><I><M><V><C><L><S><G><G><K><D><S><Y><T><L><L><D><M><L><L><Q><L><R><A><K><A><P><V><P><F><E><L><T><A><V><N><L><D><Q><K><Q><P><G><F><P><K><H><V><L><P><E><Y><L><S><S><I><G><M...
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.<BOP>
Q9PFT8
Q21U86
TATA_ALBFT
Sec-independent protein translocase protein TatA
Rhodoferax
<M><G><F><S><T><T><H><L><L><I><F><L><V><I><I><I><V><I><F><G><T><K><K><L><R><N><I><G><S><D><L><G><G><A><V><K><G><F><K><D><G><M><K><E><G><S><D><K><A><A><D><A><P><A><A><A><P><Q><Q><V><A><S><S><A><T><A><A><K><E><T><I><D><V><E><A><K><T><K><A>
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.<BOP>
Q21U86
Q8Z9A5
UPPS_SALTI
Undecaprenyl pyrophosphate synthase
Salmonella
<M><L><S><A><T><Q><P><V><S><E><N><L><P><A><H><G><C><R><H><V><A><I><I><M><D><G><N><G><R><W><A><K><K><Q><G><K><I><R><A><F><G><H><K><A><G><A><K><S><V><R><R><A><V><S><F><A><A><N><N><G><I><D><A><L><T><L><Y><A><F><S><S><E><N><W><N><R><P><A><Q><E><V><S><A><L><M><E><L><F><V><W><A><L><D><S><E><V><K><S><L><H><R><H><N><V><R><L><R...
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide c...
Q8Z9A5
Q2YIT8
VIRB4_BRUA2
Type IV secretion system protein virB4
Brucella
<M><G><A><Q><S><K><Y><A><Q><Q><L><N><N><E><R><S><L><A><P><F><I><P><F><R><S><Q><V><G><P><T><T><V><I><T><R><D><G><D><F><V><R><T><W><R><I><A><G><L><A><F><E><T><Q><D><K><E><K><L><L><I><R><K><D><Q><L><N><T><L><F><R><A><I><A><S><N><N><V><A><L><W><S><H><N><V><R><R><R><T><W><D><H><L><K><S><F><F><S><N><P><F><C><D><A><L><D><K><K...
The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice.<BOP>
Q2YIT8
A9MKB9
YBEY_SALAR
Endoribonuclease YbeY
Salmonella
<M><S><Q><V><I><L><D><L><Q><L><A><C><E><N><H><S><G><L><P><D><E><A><Q><F><Q><R><W><L><D><G><V><I><P><Q><F><Q><E><A><S><E><V><T><I><R><L><V><D><E><A><E><S><H><D><L><N><L><T><Y><R><G><K><D><K><P><T><N><V><L><S><F><P><F><E><A><P><P><G><I><E><M><P><L><L><G><D><L><I><I><C><R><Q><V><V><E><Q><E><A><Q><E><Q><D><K><P><L><E><A><H...
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.<BOP>
A9MKB9
P32779
VLP25_BORHE
Variable major outer membrane lipoprotein 25
Borrelia
<M><R><K><R><I><S><A><I><I><N><K><L><N><I><S><I><M><M><M><I><V><V><L><M><I><G><C><G><Q><Q><A><V><E><A><G><K><D><G><A><A><A><A><T><G><G><R><S><L><S><E><V><L><M><E><V><G><K><S><A><E><N><A><F><Y><S><F><M><A><L><V><P><D><T><L><G><L><R><V><T><K><D><T><K><K><N><E><V><G><G><Y><F><N><S><L><G><G><K><L><G><K><A><S><D><E><L><E><E...
The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.<BOP>
P32779
V9QFG7
TXA2_LATGE
Latrodectin-2
Latrodectus
<M><L><K><L><I><C><I><V><F><L><V><T><V><L><T><F><V><V><G><E><D><T><L><D><P><A><E><Y><G><C><P><S><D><V><D><M><A><E><L><T><E><K><N><E><V><C><L><R><C><E><D><F><H><K><E><G><V><A><F><T><L><C><K><T><N><C><F><T><T><E><Y><Y><K><N><C><V><K><D><L><E><E><A><G><K><E><T><E><E>
May increase the toxicity of alpha-latrotoxin and/or other venom components. Is non-toxic to mice and to the cockroach Periplaneta americana.<BOP>
V9QFG7
Q8NCN2
ZBT34_HUMAN
Zinc finger and BTB domain-containing protein 34
Homo
<M><D><S><S><S><F><I><Q><F><D><V><P><E><Y><S><S><T><V><L><S><Q><L><N><E><L><R><L><Q><G><K><L><C><D><I><I><V><H><I><Q><G><Q><P><F><R><A><H><K><A><V><L><A><A><S><S><P><Y><F><R><D><H><S><A><L><S><T><M><S><G><L><S><I><S><V><I><K><N><P><N><V><F><E><Q><L><L><S><F><C><Y><T><G><R><M><S><L><Q><L><K><D><V><V><S><F><L><T><A><A><S...
May be a transcriptional repressor.<BOP>
Q8NCN2
Q831N0
TSAD_ENTFA
tRNA threonylcarbamoyladenosine biosynthesis protein TsaD
Enterococcus
<M><T><I><F><T><K><E><R><K><L><L><L><A><V><E><S><S><C><D><E><T><S><V><A><V><I><E><D><G><D><K><I><L><S><N><I><V><A><S><Q><I><K><S><H><Q><R><F><G><G><V><V><P><E><V><A><S><R><H><H><V><E><Q><V><T><I><C><I><E><E><A><L><T><E><A><K><V><T><P><E><E><L><S><G><V><A><V><T><Y><G><P><G><L><V><G><A><L><L><I><G><L><S><A><A><K><A><F><A...
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct ca...
Q831N0
B2SXA0
UBIA_PARPJ
4-HB polyprenyltransferase
Paraburkholderia
<M><F><A><R><L><P><L><Y><L><R><L><V><R><M><D><K><P><I><G><S><L><L><L><L><W><P><T><L><N><A><L><W><I><A><S><D><G><H><P><T><W><P><L><L><V><I><F><T><V><G><T><V><L><M><R><S><A><G><C><A><I><N><D><Y><A><D><R><D><F><D><R><Y><V><K><R><T><E><N><R><P><I><T><S><G><K><I><K><A><W><E><A><V><A><L><A><A><A><L><S><L><L><A><F><L><L><I><L...
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-...
B2SXA0
P36195
TDT_CHICK
Terminal deoxynucleotidyltransferase
Gallus
<M><E><R><I><R><P><P><T><V><V><S><Q><R><K><R><Q><K><G><M><Y><S><P><K><L><S><C><G><Y><E><I><K><F><N><K><L><V><I><F><I><M><Q><R><K><M><G><M><T><R><R><T><F><L><M><E><L><A><R><S><K><G><F><R><V><E><S><E><L><S><D><S><V><T><H><I><V><A><E><N><N><S><Y><P><E><V><L><D><W><L><K><G><Q><A><V><G><D><S><S><R><F><E><I><L><D><I><S><W><L...
Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the mat...
P36195