PrimeKG-CL Benchmark v1.0
A continual graph learning benchmark on a real biomedical knowledge graph with genuine temporal evolution.
Snapshots
snapshots/kg_t0.csv— June 2021 PrimeKG release. 8,100,498 triples, 129,375 nodes, 30 relations.snapshots/kg_t1.csv— July 2023 reconstruction from nine upstream databases (Bgee, CTD, GO, Gene2GO, HPO, HPOA, MONDO, Uberon, HGNC). 13,001,666 triples, 134,211 nodes, 25 relations.snapshots/t1_build_info.json— provenance / database versions used for the t_1 reconstruction.
Temporal diff (t_0 -> t_1)
- Added: 5,760,234 new triples (driven by GO annotations, disease-phenotype refinement, drug-target updates)
- Removed: 888,848 deprecated triples (retracted associations, ontology corrections)
- Persistent: 7,208,624 triples unchanged across both snapshots
Full breakdown in diffs/diff_t0_t1.json.
Continual learning tasks
10 entity-type-grouped tasks (tasks/task_*). Each directory contains
train.txt, valid.txt, test.txt, one tab-separated triple per line
(head_id<TAB>relation<TAB>tail_id). 70/10/20 train/valid/test split.
task_0_base 8,100,498 triples (full t_0)
task_1_disease_related 17,009
task_1_drug_related 125,343
task_2_disease_related 115,382
task_2_gene_protein 2,850,593
task_3_gene_protein 99,761
task_3_phenotype_related 47,997
task_4_biological_process 116,118
task_4_phenotype_related 57,390
task_5_anatomy_pathway 2,752,675
Stratified evaluation
test_stratification.json — per-task partition of test triples into
persistent (in both snapshots), added (new in t_1), and
removed (only in t_0) strata, supporting stratified-MRR analysis of
correct retention vs. correct forgetting.
Task 0's test split: 1,443,243 persistent + 176,856 removed = 1,620,099 total.
Multimodal features (features/)
text_embeddings.pt— BiomedBERT [CLS] embeddings projected to 256-d. Coverage: 36% of entities (those with textual descriptions).mol_features.pt— Morgan fingerprints (radius 2, 1024 bits) for drugs with available SMILES. Coverage: 4% of entities.edge_index.pt,edge_type.pt— R-GCN message-passing tensors for the full t_0 graph (used by the structural encoder).node_has_text.pt,node_has_mol.pt— boolean coverage masks.node_index_map.csv— global entity_id <-> row_index map.vocab_sizes.json— entity / relation vocab sizes.
Files
LICENSE MIT (code) + CC BY 4.0 (data)
croissant.json MLCommons Croissant metadata
README.md this file
statistics.json benchmark-level summary
test_stratification.json per-task persistent/added/removed counts
diffs/diff_t0_t1.json full t_0->t_1 diff with per-relation breakdown
snapshots/ kg_t0.csv, kg_t1.csv, build provenance
tasks/ 10 task directories with train/valid/test splits
features/ multimodal node features
Citation
@inproceedings{primekgcl2026,
title={PrimeKG-CL: A Continual Graph Learning Benchmark on Evolving Biomedical Knowledge Graphs},
author={Anonymous},
booktitle={NeurIPS Datasets and Benchmarks Track},
year={2026}
}
License
- Code components: MIT.
- Data files: CC BY 4.0, inheriting PrimeKG's license; users must respect upstream-database licenses where applicable.
- See
LICENSEfor details.