PrimeKGCL / benchmark /README.md
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PrimeKG-CL Benchmark v1.0

A continual graph learning benchmark on a real biomedical knowledge graph with genuine temporal evolution.

Snapshots

  • snapshots/kg_t0.csv — June 2021 PrimeKG release. 8,100,498 triples, 129,375 nodes, 30 relations.
  • snapshots/kg_t1.csv — July 2023 reconstruction from nine upstream databases (Bgee, CTD, GO, Gene2GO, HPO, HPOA, MONDO, Uberon, HGNC). 13,001,666 triples, 134,211 nodes, 25 relations.
  • snapshots/t1_build_info.json — provenance / database versions used for the t_1 reconstruction.

Temporal diff (t_0 -> t_1)

  • Added: 5,760,234 new triples (driven by GO annotations, disease-phenotype refinement, drug-target updates)
  • Removed: 888,848 deprecated triples (retracted associations, ontology corrections)
  • Persistent: 7,208,624 triples unchanged across both snapshots

Full breakdown in diffs/diff_t0_t1.json.

Continual learning tasks

10 entity-type-grouped tasks (tasks/task_*). Each directory contains train.txt, valid.txt, test.txt, one tab-separated triple per line (head_id<TAB>relation<TAB>tail_id). 70/10/20 train/valid/test split.

task_0_base                    8,100,498 triples (full t_0)
task_1_disease_related            17,009
task_1_drug_related              125,343
task_2_disease_related           115,382
task_2_gene_protein            2,850,593
task_3_gene_protein               99,761
task_3_phenotype_related          47,997
task_4_biological_process        116,118
task_4_phenotype_related          57,390
task_5_anatomy_pathway         2,752,675

Stratified evaluation

test_stratification.json — per-task partition of test triples into persistent (in both snapshots), added (new in t_1), and removed (only in t_0) strata, supporting stratified-MRR analysis of correct retention vs. correct forgetting.

Task 0's test split: 1,443,243 persistent + 176,856 removed = 1,620,099 total.

Multimodal features (features/)

  • text_embeddings.pt — BiomedBERT [CLS] embeddings projected to 256-d. Coverage: 36% of entities (those with textual descriptions).
  • mol_features.pt — Morgan fingerprints (radius 2, 1024 bits) for drugs with available SMILES. Coverage: 4% of entities.
  • edge_index.pt, edge_type.pt — R-GCN message-passing tensors for the full t_0 graph (used by the structural encoder).
  • node_has_text.pt, node_has_mol.pt — boolean coverage masks.
  • node_index_map.csv — global entity_id <-> row_index map.
  • vocab_sizes.json — entity / relation vocab sizes.

Files

LICENSE                       MIT (code) + CC BY 4.0 (data)
croissant.json                MLCommons Croissant metadata
README.md                     this file
statistics.json               benchmark-level summary
test_stratification.json      per-task persistent/added/removed counts
diffs/diff_t0_t1.json         full t_0->t_1 diff with per-relation breakdown
snapshots/                    kg_t0.csv, kg_t1.csv, build provenance
tasks/                        10 task directories with train/valid/test splits
features/                     multimodal node features

Citation

@inproceedings{primekgcl2026,
  title={PrimeKG-CL: A Continual Graph Learning Benchmark on Evolving Biomedical Knowledge Graphs},
  author={Anonymous},
  booktitle={NeurIPS Datasets and Benchmarks Track},
  year={2026}
}

License

  • Code components: MIT.
  • Data files: CC BY 4.0, inheriting PrimeKG's license; users must respect upstream-database licenses where applicable.
  • See LICENSE for details.