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\documentclass{article} |
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\usepackage{booktabs} |
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\usepackage{longtable} |
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\usepackage{array} |
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\usepackage{geometry} |
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\geometry{margin=1in} |
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\begin{document} |
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\section{Generated AMP Sequences with MIC Values} |
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\subsection{No CFG (0.0) Setting} |
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\begin{table}[h!] |
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\centering |
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\caption{All generated AMP sequences for No CFG (0.0) setting with corresponding MIC values.} |
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\label{tab:amp_sequences_no_cfg_00} |
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\begin{tabular}{|c|c|c|} |
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\hline |
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\textbf{Rank} & \textbf{Sequence} & \textbf{MIC (μg/mL)} \\ |
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\hline |
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1 & \texttt{KQTSDKIWQIWIMMHGLDRPPIQGSLDNDQHWFNGHTVTENLDDKELDFH} & 239.4 \\ |
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\hline |
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2 & \texttt{GNCSCAHRRATYLQDDHKHTREYCGRNESRKPAGPGCCHDTCWRTLQQKN} & 244.5 \\ |
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\hline |
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3 & \texttt{ENEFIRHGCMTDYKSNAILNGQNNVTNQIEWWMLREGSQERKEVFQAGPC} & 247.0 \\ |
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\hline |
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4 & \texttt{GKGEHRYQEIKSDELNTEESNQKCLDKNFNKTYEKGGMMQFDEQANIPSF} & 247.1 \\ |
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\hline |
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5 & \texttt{GARKDMGWDISPSLHAKWRHSVEDQNMYCTENIPMELNPNCFHVGEVAWI} & 259.2 \\ |
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\hline |
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6 & \texttt{ETVHQVSRSRREQGEKFPEPKYWGGVCHTGNMQPRSIYFGEQHLGRRKNW} & 260.4 \\ |
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\hline |
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7 & \texttt{DRSASNHGPRACAQWPCQSRPNGNLHTWCWWYTWSRTTRLYKNMNCEWGS} & 261.3 \\ |
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\hline |
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8 & \texttt{PRFWVPQMGLRWDNECKEQYGGHSMGKMHFHKIHDEFSIRPPNDALAFGP} & 265.5 \\ |
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\hline |
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9 & \texttt{TMHDPNRYISENQTNTYNNIPGIDYQYQPWWRMWKDKANPLMPGLTHHTN} & 270.6 \\ |
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\hline |
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10 & \texttt{ACWSNTSQSACQSIQQNTDHTWFNAYPHSTTRGMYPGMSAGYAQSLCDVE} & 270.9 \\ |
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\hline |
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11 & \texttt{WMCISPVTQKEESKKPIYTCYVTDSQKMCGGKDSPGSFQFNWRRIGDHPF} & 271.8 \\ |
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\hline |
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12 & \texttt{HCQQCFSHMDFWEMRSMAITALIAWFGSWFEQRVIFPKMSPDFSHRWDMH} & 272.2 \\ |
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\hline |
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13 & \texttt{WNCMRYRKPAYATSQPPRMGTLNLCRFSDHNDDVWIHQNISYQCVFECPH} & 272.6 \\ |
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\hline |
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14 & \texttt{VYHACETAHHNIWGSEHNNGPKTSTPASTWCYWHKLMDVINEPMKMVPFA} & 275.8 \\ |
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\hline |
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15 & \texttt{AGCRVKAPCHWEPVYSACDAIMMESWHQPCMQVSPCRRYKCMCMIGAPAN} & 276.6 \\ |
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\hline |
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16 & \texttt{LAVQAHNIHATDFDHTLYQDHFLTLMGTSVISSEEGWDLVGKEIKYGIPK} & 277.7 \\ |
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\hline |
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17 & \texttt{VCMTVVIAHRMDLSYDYPCWGERRQYGGMTGEHHSAPQWQLWFAPHGPIM} & 278.9 \\ |
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\hline |
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18 & \texttt{WSFTCSDNDNSLHDLNPYMHLLDSKDDQGKWGVFQHPTCSLRMTCQLNWH} & 279.8 \\ |
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\hline |
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19 & \texttt{EPDGCTTWPWAIRWRVMIIQCHEPRTHSEYPLSGMPGDFYKEPPMQNPPC} & 280.8 \\ |
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\hline |
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20 & \texttt{SEEHPPTNMDMVQNVAGCALTIGYAAHISRAEAPKWLHSLLLLVDCWFGP} & 281.5 \\ |
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\hline |
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\end{tabular} |
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\end{table} |
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\subsection{Weak CFG (3.0) Setting} |
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\begin{table}[h!] |
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\centering |
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\caption{All generated AMP sequences for Weak CFG (3.0) setting with corresponding MIC values.} |
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\label{tab:amp_sequences_weak_cfg_30} |
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\begin{tabular}{|c|c|c|} |
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\hline |
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\textbf{Rank} & \textbf{Sequence} & \textbf{MIC (μg/mL)} \\ |
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\hline |
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1 & \texttt{PSKMPMGYWLHHKYNVCALNPPKHHNNNLKTLMKHSHAHPQPRECNWSWS} & 230.8 \\ |
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\hline |
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2 & \texttt{SGWRTNDAKCMQWEELYRGRDAPMYKAFTADKRAWVLWWEYHMSHYIVTK} & 232.2 \\ |
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\hline |
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3 & \texttt{NCPICFKPGHYLALPTPFEGLPFQTTTSWAFWGHLRYICYKHSHVFTRPK} & 249.9 \\ |
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\hline |
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4 & \texttt{GFEGLKYRPKIQTGQNTRSTAIMFPQCGYPMCKNGEVKAYSEDWNSPGDE} & 253.7 \\ |
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\hline |
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5 & \texttt{RVYALKILGNDDIALYSNELPSGNLFLWSVATEDCKRYMIMIPADMNEEC} & 258.7 \\ |
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\hline |
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6 & \texttt{NEEGPCPHNMTNYETGGMCFLAQRVPPKPQKSQWKPSPHEIIMAYWMFSW} & 264.7 \\ |
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\hline |
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7 & \texttt{GRNRDQSIETHMPAQENDNYGSYKWTKSTCIMGHTFTIYQPMGWTKCCIM} & 266.5 \\ |
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\hline |
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8 & \texttt{WARKPAYSGMGWANGRDNLFPMDPETLTCEKNSRVQIATYHAEPPSQTPW} & 270.0 \\ |
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\hline |
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9 & \texttt{ANGEAPIPGFICEIGVFCRTQMCLEHPQCPQIASSSTHKLCQAKKFARWI} & 272.0 \\ |
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\hline |
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10 & \texttt{TSFRSWWHHQPYFFQCPDGPPGGPVKFNDFRRCKEHRWPRGPWCPALPAE} & 273.2 \\ |
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\hline |
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11 & \texttt{PGCDADWCNNPKHQVAWFFWRGWWGHLVKPQIYWSGYNPNECLFVQNTEF} & 273.3 \\ |
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\hline |
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12 & \texttt{YPSRSMTPRNPAYTMHNDCDANHCPQFPWSNLEQTGPVWNHMRPPLEPYI} & 273.9 \\ |
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\hline |
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13 & \texttt{ETVLSMRQENRQLDFTDSERDWVMHAWLQTATDYFLVPQCCHHHGAWMAI} & 274.6 \\ |
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\hline |
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14 & \texttt{IETHIWWLQNDSHPCYILVILNPTKKWEYLWPDGWIFKSHCINQADHISF} & 275.8 \\ |
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\hline |
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15 & \texttt{KVGHQHDLCGKAASNLFMMAFWNIEMKQYHDALSFKNAPIGSNWWCSGRH} & 275.8 \\ |
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\hline |
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16 & \texttt{WEQCAMSLLSAVFFGMFGDMNIQSGNRIYRCIYPQHYQIPHHEHHWCSYT} & 275.9 \\ |
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\hline |
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17 & \texttt{GDDIIAGMPEGESRPWAIHYVYVDPNRYAHWGWHSNHRAKAKMTPGLAST} & 276.4 \\ |
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\hline |
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18 & \texttt{HPYGAHCDVNCAHGNAWCHDFHGDHNMNGEQRREMNTLDEFWSTLMCMSA} & 278.4 \\ |
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\hline |
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19 & \texttt{SHCTIIPQYIAPGVLGKDEMCEISYGYELPFPYVNCPHRDGHVANYPGKH} & 278.4 \\ |
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\hline |
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20 & \texttt{PMTHGDQGKTDNTPHSPVTKNMEEVNPACHEQPIPGRLQTSVFLLTNNRK} & 279.1 \\ |
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\hline |
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\end{tabular} |
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\end{table} |
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\subsection{Strong CFG (7.5) Setting} |
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\begin{table}[h!] |
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\centering |
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\caption{All generated AMP sequences for Strong CFG (7.5) setting with corresponding MIC values.} |
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\label{tab:amp_sequences_strong_cfg_75} |
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\begin{tabular}{|c|c|c|} |
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\hline |
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\textbf{Rank} & \textbf{Sequence} & \textbf{MIC (μg/mL)} \\ |
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\hline |
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1 & \texttt{QWHCCRKQGIVAHNSKFPSKKPVIWHRGEASLERNHKGWDPCNCGPRARP} & 175.4 \\ |
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\hline |
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2 & \texttt{CRCLQQMFHWSNVKSFAKDQEVMPTELQPYKWWRGRYMPIENSIKMELAY} & 200.8 \\ |
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\hline |
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3 & \texttt{HWVRLHTEIGVHMGCFLCKWRKCQDIGEKHKDQKEYQVMWMKPQHGACLP} & 243.0 \\ |
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\hline |
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4 & \texttt{QWLTHVRYITYLLCLYNEICSVLRVYPTSTHLFWRNNREARNTWQWPFFT} & 250.4 \\ |
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\hline |
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5 & \texttt{TAHNWMFPHLNQQHRKIMRFQWSTDNIGCCGGPSDCNWHQTPDKEPRSRD} & 252.5 \\ |
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\hline |
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6 & \texttt{STRAIDAAKLMSKLQVTSWNSPHWSHQIGCQIGRYRRGEHCEWDEYWDRC} & 256.3 \\ |
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\hline |
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7 & \texttt{KLAFPWYEVIPDKASEGANRPPIRDKFYDSPTGPYKQDCPDWPGLMLRWT} & 260.8 \\ |
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\hline |
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8 & \texttt{QTSSMPNSCTSWHGIKALKYQHAEKSRPPGPNMGLNNRHFTFMHNYKPHY} & 261.2 \\ |
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\hline |
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9 & \texttt{LHFTHHLDSCRMQWEYLRGNLPRNHIGIPMMGKLLNVAGVEHGGLSQCRY} & 263.5 \\ |
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\hline |
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10 & \texttt{RTKPTIHCSPIYHSMQGYTNSARPAYWNDNCPMWGILWKDNPSWVERKQH} & 266.8 \\ |
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\hline |
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11 & \texttt{CETHNMYNWRNLQIESMPCQIKMSRTDSNQGAYEWCSAQGFKGKWICWSW} & 268.0 \\ |
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\hline |
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12 & \texttt{HHGGARLQDDWGSDRFNEMNIHQHETALCWHTDPMPIKARECWERSQCGC} & 268.4 \\ |
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\hline |
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13 & \texttt{HNTCSPHLWTGHNKNTPYWEWCGPHCCGTQFNMGGKHQLWGTMQPVMHHN} & 271.8 \\ |
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\hline |
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14 & \texttt{ATEDSWMENCHDTASQQDINEDQFLHYCWDHIEPSDPITNEWACWKKYEW} & 273.6 \\ |
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\hline |
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15 & \texttt{MITIGTQRPTYNAIIDTQDHHYRNMPTRRVAHCEETVFWPNRTPKWKQKD} & 275.4 \\ |
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\hline |
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16 & \texttt{QGMPVGSIQNKHDCEYSYPNYTTYWTHPQQWNSMSRLHGSQGGNDNWLHN} & 275.5 \\ |
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\hline |
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17 & \texttt{KHKTSGMWELRIFIMAGQTAHDCWTCMGMMNNAEQNAPFTWNQCNQGFNN} & 276.5 \\ |
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\hline |
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18 & \texttt{CWSSCCWATYPFPAEWVWPQCCTGAARVMFHIHFKETFAMNPWGHCEGAP} & 280.2 \\ |
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\hline |
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19 & \texttt{TLMFQASLVMYNRKGMFSNKRDGGCNPSWEPSLHNQFPCCVNSKADSGDH} & 280.7 \\ |
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\hline |
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20 & \texttt{GGNAPMESENANWKPRDFMEYTADDGIASGNFQAKELKTSSKLDDTYNCT} & 282.5 \\ |
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\hline |
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\end{tabular} |
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\end{table} |
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\subsection{Very Strong CFG (15.0) Setting} |
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\begin{table}[h!] |
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\centering |
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\caption{All generated AMP sequences for Very Strong CFG (15.0) setting with corresponding MIC values.} |
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\label{tab:amp_sequences_very_strong_cfg_150} |
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\begin{tabular}{|c|c|c|} |
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\hline |
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\textbf{Rank} & \textbf{Sequence} & \textbf{MIC (μg/mL)} \\ |
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\hline |
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1 & \texttt{KGLVRIYGSPQTMTECARCTDRCRMHTKSKSRTLSVVIGFYMHPKWKQAY} & 238.7 \\ |
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\hline |
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2 & \texttt{LRTTRHIEKIWINGNGDAACKDMALHWMKQSECKPEYCMSLPLTRAGMYT} & 241.9 \\ |
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\hline |
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3 & \texttt{RWFPNTFPAYMQRQKRAQDFRYPGQGGQVIRSTDDHYWCITYRFWIKKEH} & 243.0 \\ |
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\hline |
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4 & \texttt{NNLKINCGAINCWNPNPAMHRQPGVCTHKIGKMGSIGMCNMAKSHSMYDE} & 252.4 \\ |
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\hline |
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5 & \texttt{NTSLKATYRWIRCTLECSETFLEGYIEHQLVNHYIECIAQQSEMKKRPYV} & 254.6 \\ |
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\hline |
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6 & \texttt{LQEWEHVTYDHLSPRTAGTCKGASCQIKCNEFWQTGNNMSQKWGKASRGI} & 256.3 \\ |
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\hline |
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7 & \texttt{PIWMLRYIVQHASPGQLATHYMAKRGSRTPRSDMHPNEHIHQNFEAHTIW} & 257.7 \\ |
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\hline |
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8 & \texttt{RNPGVLRWEWQTGNGLMNNESLSLPSPEDTTMMPHVLLVTSTHTGDKEFH} & 263.1 \\ |
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\hline |
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9 & \texttt{CWYTMGTHKCPAAPLCGSGLYIELTDWWNVLMMAHMPPVFYQMEIPHNLN} & 268.6 \\ |
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\hline |
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10 & \texttt{AGMQWHNSTPDTYRCPHAWNFDQAKENWHWHVPTVSWRLMLGHGQPFSWW} & 269.4 \\ |
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\hline |
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11 & \texttt{YEEMMQKGSNDSKCNAFCKWHEQNTNWYPGFCFTWDWWICYYLPEWTQYH} & 270.8 \\ |
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\hline |
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12 & \texttt{FPVWLLRPWELLGGPAWEQNCFQANPVPSQKQGCWLWDKDLIPAVQDLLP} & 271.4 \\ |
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\hline |
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13 & \texttt{RAYNMYHSSFDFGKPKSMWVHYPPGCWSTDLFVAAGCSEEGGVRYFNWLI} & 275.9 \\ |
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\hline |
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14 & \texttt{LVLYPPNMKGCFMWFAPRNSNCNTEITNGFTHNNQTNQFGPVHFPTNNFF} & 276.6 \\ |
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\hline |
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15 & \texttt{VPQPLNSGARYAKFYQVGQRCDPTRGVPYTGLPFTCQPYEFCSQGCYIWI} & 277.8 \\ |
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\hline |
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16 & \texttt{THMTCPAQHENWWRKVTGSGTEGGMYGVGHSAALNYGQDPGCHSWERWRQ} & 278.9 \\ |
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\hline |
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17 & \texttt{WESPFLYPQVEGGAPSHLETTMDQNGVKGAKDWKPHVWDLWGHDGSACQS} & 279.7 \\ |
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\hline |
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18 & \texttt{SHWWTWGYQGKHWQYDLMEPQGHTNGLWRCNFNSPSARDTEDGICAGRNH} & 280.9 \\ |
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\hline |
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19 & \texttt{SNNPNMMVHQTASSNAVQTPDQYLQWMDDRPEFRSEGTVHALIPWISAMW} & 282.1 \\ |
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\hline |
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20 & \texttt{FTDECARHGLVPSMSACWHILCVPGSQSNTNEAENPHPPNWLDTNQHGHM} & 282.3 \\ |
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\hline |
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\end{tabular} |
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\end{table} |
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\section{Summary Statistics} |
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\begin{table}[h!] |
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\centering |
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\caption{Summary statistics of MIC values across different CFG settings.} |
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\label{tab:mic_statistics} |
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\begin{tabular}{|c|c|c|c|c|c|} |
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\hline |
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\textbf{CFG Setting} & \textbf{N} & \textbf{Mean MIC} & \textbf{Min MIC} & \textbf{Max MIC} & \textbf{Std MIC} \\ |
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\hline |
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Strong CFG 7.5 & 20 & 259.2 & 175.4 & 282.5 & 26.2 \\ |
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\hline |
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Weak CFG 3.0 & 20 & 266.7 & 230.8 & 279.1 & 14.2 \\ |
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\hline |
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Very Strong CFG 15.0 & 20 & 266.1 & 238.7 & 282.3 & 13.9 \\ |
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\hline |
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No CFG 0.0 & 20 & 266.7 & 239.4 & 281.5 & 12.8 \\ |
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\hline |
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\end{tabular} |
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\end{table} |
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\end{document} |
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