| | --- |
| | license: mit |
| | language: |
| | - en |
| | tags: |
| | - arch3d |
| | - genomics |
| | - Hi-C |
| | - foundation-model |
| | - genome-architecture |
| | - global-genome-architecture |
| | - chromosome-conformation-capture |
| | --- |
| | |
| | # ARCH3D: A foundation model for global genome architecture |
| |
|
| | This repository contains the checkpoints |
| | - `pretrained.ckpt`: Pre-trained ARCHED with the pre-training task head |
| | - `enhanced.ckpt`: ARCH3D fine-tuned for resolution enhancement |
| | - `hyperedge.ckpt`: ARCH3D with a task head for predicting hyperedges |
| |
|
| | If you use this model in your work, please cite: |
| |
|
| | Galioto, Nicholas, et al. "ARCH3D: A foundation model for global genome architecture." _bioRxiv_ (2026): 2026-02. |
| | ```bibtex |
| | @article{galioto2026arch3d, |
| | title={{ARCH3D}: A foundation model for global genome architecture}, |
| | author={Galioto, Nicholas and Stansbury, Cooper and Gorodetsky, Alex Arkady and Rajapakse, Indika}, |
| | journal={bioRxiv}, |
| | pages={2026--02}, |
| | year={2026}, |
| | publisher={Cold Spring Harbor Laboratory} |
| | } |
| | ``` |