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metadata
license: mit
library_name: pyaging
tags:
  - pyaging
  - aging-clock
  - biology
  - dna-methylation

hep

HepClock is a hepatocyte-specific chronological-age clock trained by lasso on hepatocyte age-DMCTs identified with CellDMC after estimating five liver cell fractions.

Predicts chronological age
Species Homo sapiens
Tissue liver
Data type DNA methylation
Model type LASSO regression
Year 2024

Use with pyaging

import pyaging as pya

pya.pred.predict_age(adata, ["hep"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Tong, Huige, et al. "Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution." Aging 16 (2024): 14204–14237.

https://doi.org/10.18632/aging.206184