| title: Virtual Gene Scope v2.0 | |
| emoji: 🧬 | |
| colorFrom: purple | |
| colorTo: blue | |
| sdk: docker | |
| app_port: 8501 | |
| pinned: false | |
| license: apache-2.0 | |
| tags: | |
| - streamlit | |
| - nursing | |
| - genomics | |
| - alphagenome | |
| - pharmacogenomics | |
| - uk-nursing | |
| - nmc | |
| # 🧬 Virtual Gene Scope v2.0 | |
| **Explore the Regulatory Genome with Google DeepMind's AlphaGenome.** | |
| An educational tool for nursing students and healthcare professionals to visualise how non-coding genetic variants affect gene regulation — covering expression, splicing, chromatin accessibility, and contact maps. | |
| > *Built by nurses who code. For nurses who care about genomics.* | |
| > *Part of the [CQAI Nursing Education Toolkit](https://github.com/Clinical-Quality-Artifical-Intelligence)* | |
| --- | |
| ## ⚕️ Clinical Disclaimer | |
| This tool is for **educational purposes only**. It does not make clinical decisions and must not be used for patient care without independent verification by qualified healthcare professionals. | |
| --- | |
| ## ✨ Features | |
| - 🏥 **Disease Risk Mode** — Explore pathogenic variants in 8 disease-associated genes | |
| - 💊 **Drug Response Mode (PGx)** — See how variants affect drug metabolism (8 PGx genes) | |
| - 🧪 **Custom Variant Mode** — Input any variant and see predicted effects | |
| - 🫀 **Tissue Context** — Select from 10 tissue types with UBERON ontology terms | |
| - 📊 **Multi-modal Demo Tracks** — RNA expression, splicing, chromatin accessibility | |
| - 👩⚕️ **Nursing Reference Cards** — NMC-aligned clinical guidance per gene | |
| - 📎 **DOCX Report Export** — Download a formatted gene analysis report | |
| - 🔗 **ClinVar / PharmGKB / OMIM links** — Direct links to authoritative databases | |
| - 🎓 **NMC Proficiency Map** — Standards of Proficiency alignment per gene | |