feat(sv): structural-variant modality (ADR-0008) — fusions, with three gates

feat(panel): widen 19 → 29 genes (HR + MMR), and stop silently dropping uncurated genes

fix: empty-genes parity + name the reason in the mouse BYOD refusal

feat(api): expose samples_profiled so callers can reconstruct WT

merge: cohort survey + denominator fix into main (ADR-0006/0007)

cadence: re-curation policy for curated artifacts (ADR-0007)

cohorts: +2 curated (6 total); fix frequency denominators (TCGA KRAS 73%->91%)

C2 + C3: per-study license gate and polite client — source conditions complete

M3 deploy surface: gradio_ui.py + src/server.py

M1: cBioPortal status-matrix curation + query_variant_status

scaffold: pdac-genomics-agent — third specialist for PDAC DNA (mutation/CNV) analysis