fix(sv): read the frame claim out of `annotation`, and re-curate MSK

fix(sv): read MSK's hyphenated frame claim, in the classifier AND the depth gate

feat(sv): structural-variant modality (ADR-0008) — fusions, with three gates

merge: cohort survey + denominator fix into main (ADR-0006/0007)

cadence: re-curation policy for curated artifacts (ADR-0007)

cohorts: +2 curated (6 total); fix frequency denominators (TCGA KRAS 73%->91%)

C2 + C3: per-study license gate and polite client — source conditions complete

C4: curate-and-cache — the cBioPortal API leaves the request path

M3: BYOD upload + deploy hardening

M1: cBioPortal status-matrix curation + query_variant_status

scaffold: pdac-genomics-agent — third specialist for PDAC DNA (mutation/CNV) analysis