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Answer the following medical question with one of the provided options:
Q:A 55-year-old black male otherwise healthy presents for a yearly physical. No significant past medical history. Current medications are a multivitamin and rosuvastatin 20 mg orally daily. Vitals are temperature 37°C (98.6°F), blood pressure 155/75 mm Hg, pulse 95/min, respirations 16/min, and oxygen saturation 99% on...
E: Admit to hospital for aortic valve replacement
Answer the following medical question with one of the provided options:
Q:A 44-year-old woman presents to the outpatient infectious disease clinic. She has a known history of HIV, well-controlled on HAART for the past 8 years. She currently has no additional significant medical conditions. She feels well and a physical examination is within normal limits. She denies any current tobacco use...
B: Kaposi’s sarcoma
Answer the following medical question with one of the provided options:
Q:A 13-year-old boy presents to the emergency department with severe right-lower-quadrant abdominal pain. Workup reveals acute appendicitis, and he subsequently undergoes laparoscopic appendectomy. The appendix is sent for histological examination. A pathologist reviews the slide shown in the image below. Which stateme...
A: In children, appendicitis can frequently arise from certain changes in these structures.
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Q:A 21-year-old female college student is brought to the university clinic by her roommates. They became worried because they noted long strands of hair all over the dormitory room floor. This has progressively worsened, with the midterms approaching. During discussions with the physician, the roommates also mention th...
A: Cognitive-behavior therapy or behavior modification
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Q:A 47-year-old Hispanic man presents with complaints of recent heat intolerance and rapid heart rate. The patient has also experienced recent unintentional weight loss of 15 pounds. Physical exam reveals tachycardia and skin that is warm to the touch. A radioactive iodine uptake scan of the thyroid reveals several foc...
B: Low TSH and high T4
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Q:A 74-year-old man is brought to the emergency department because of increasing abdominal pain and distention for 3 days. The pain is diffuse and colicky, and he describes it as 4 out of 10 in intensity. His last bowel movement was 5 days ago. He has not undergone any previous abdominal surgeries. He has hypertension,...
B: Neostigmine therapy
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Q:A 68-year-old man comes to the physician because of a 2-day history of a rash across his trunk and extremities. For the past 3 months, he has had persistent pruritus in these areas. He started hiking in the woods with his grandson last week to try to lose weight. His grandson, who often spends the weekends with him, ...
C: Linear deposits of IgG and C3 along the basement membrane on direct immunofluorescence studies
Answer the following medical question with one of the provided options:
Q:A 51-year-old man is undergoing chemotherapy treatment for a rapidly progressive newly-diagnosed acute myelogenous leukemia. On day 4 of his hospitalization, the patient is noted to be obtunded. Other than the chemotherapy, he is receiving lansoprazole, acetaminophen, and an infusion of D5–0.9% normal saline at 50 mL...
D: Calcium chloride
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Q:A 4-year-old boy is brought to the pediatrician’s office for a flu-like episode. His father tells the physician that his child has fallen ill several times over the past few months. He also has occasional bouts of night sweats and loss of appetite. He has lost 5 lbs (2.3 kg) in the last 6 months. At the pediatrician’...
B: Alzheimer’s disease
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Q:A 21-year-old man comes to the military base physician for evaluation of progressive discomfort in his right shoulder for the past 4 months. He joined the military 6 months ago and is part of a drill team. In anticipation of an upcoming competition, he has been practicing rifle drills and firing exercises 8 hours a d...
D: Myositis ossificans
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Q:A 5-year-old girl is brought to the physician by her mother because of a 3-week history of a foul-smelling discharge from the left nostril. There was one episode of blood-tinged fluid draining from the nostril during this period. She has been mouth-breathing in her sleep for the past 4 days. She was born at term. Her...
B: Foreign body extraction
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Q:A previously healthy 57-year-old man is brought to the emergency department because of a 3-day history of fever and headache. He also has nausea and vomited twice in the past 24 hours. His temperature is 39.1°C (102.4°F). He is lethargic but oriented to person, place, and time. Examination shows severe neck rigidity ...
D: Encapsulated, gram-positive cocci in pairs
Answer the following medical question with one of the provided options:
Q:A 35-year-old G2P0 presents to her physician to discuss the results of her 16-week obstetric screening tests. She has no complaints. Her previous pregnancy at 28 years of age was a spontaneous abortion in the first trimester. She has no history of gynecologic diseases. Her quadruple test shows the following findings:...
B: Maternal age is a significant risk factor for the condition of the patient, the increased risk of which is indicated by the results of the study.
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Q:A 35-year-old man comes to the clinic complaining of yellow discoloration of his skin and eyes for the past week. He also complains about loss of appetite, nausea, malaise, and severe tiredness. He has no known past medical history and takes over-the-counter acetaminophen for headache. He has smoked a half pack of ci...
D: HbsAg and Anti-IgM Hbc
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Q:A 42-year-old woman presents with loss of sensation in her left arm and hand. A rapid evaluation is performed to rule out stroke. No other focal neurologic deficits are found except for a loss of fine touch sensation in a C6 dermatome pattern. Further evaluation reveals that the patient was recently sick with an uppe...
B: Dorsal root ganglion
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Q:Lipidator is a nonionic surfactant that is used to disrupt the lipid membranes of cells. This disruption of the lipid membrane results in the release of all of its cytoplasmic contents. Which of the following viruses would not be disrupted if treated with this detergent?? {'A': 'Herpesvirus', 'B': 'Hepadnavirus', 'C'...
D: Picornavirus
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Q:A 52-year-old woman presents to her primary care physician with a 1-week history of facial drooping. Specifically, she has noticed that the left side of her face does not move when she tries to smile. Furthermore, she has been having difficulty closing her left eye. Her past medical history is significant for hyperte...
B: Internal auditory meatus
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Q:A 47-year-old woman comes to the physician because of a 5-month history of insomnia. She frequently experiences leg discomfort when trying to fall asleep that is relieved temporarily by movement. Her husband tells her that she frequently flexes her ankles upward when she sleeps. She appears fatigued and anxious. Phys...
A: Ropinirole
Answer the following medical question with one of the provided options:
Q:A 72-year-old man comes to the emergency department for progressively worsening abdominal pain. The pain began 2 weeks ago and is localized to the right upper quadrant. He feels sick and fatigued. He also reports breathlessness when climbing the stairs to his first-floor apartment. He is a retired painter. He has hyp...
C: Hepatic vein obstruction
Answer the following medical question with one of the provided options:
Q:A 59-year-old man is brought to the emergency department because of a 2-hour history of abdominal pain and severe vomiting after ingesting an unknown medication in a suicide attempt. On the way to the hospital, he had a generalized tonic-clonic seizure. He has chronic obstructive pulmonary disease, coronary artery di...
B: Theophylline
Answer the following medical question with one of the provided options:
Q:A 26-year-old woman presents to the clinic today complaining of weakness and fatigue. She is a vegetarian and often struggles to maintain an adequate intake of non-animal based protein. She currently smokes 1 pack of cigarettes per day, drinks a glass of wine per day, and she currently denies any illicit drug use. He...
A: Iron replacement for 4–6 months
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Q:An autopsy was performed on a 2-year-old male child. The clinical report stated that the child's parents were first cousins, and that he had deteriorated physically and mentally over the past year, becoming deaf, unable to eat, and paralyzed. A brain biopsy demonstrated the accumulation of GM2-gangliosides in the neu...
D: Hexosaminidase A
Answer the following medical question with one of the provided options:
Q:A 70-year-old woman comes to the physician for a follow-up examination 2 months after undergoing a total hip replacement surgery. She reports that she has persistent difficulty in walking since the surgery despite regular physiotherapy. Examination of her gait shows sagging of the left pelvis when her right leg is we...
E: Right superior gluteal nerve
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Q:A 35-year-old man seeks evaluation at a clinic with a 2-week history of pain during urination and a yellow-white discharge from the urethra. He has a history of multiple sexual partners and inconsistent use of condoms. He admits to having similar symptoms in the past and being treated with antibiotics. On genital exa...
B: Protein pili
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Q:A 35-year-old woman is diagnosed with schizophrenia after nine months of experiencing auditory hallucinations and persecutory delusions. Over the next year, she fails to experience symptom relief from separate and appropriately dosed trials of olanzapine, quetiapine, and risperidone. At this point, which of the follo...
C: Clozapine
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Q:A 54-year-old woman comes to the physician because of an ulcer on her left ankle for 6 years. She has had multiple ulcers over her left lower extremity during this period that have subsided with wound care and dressing. She has type 2 diabetes mellitus and gastroesophageal reflux disease. Current medications include ...
E: Punch biopsy "
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Q:A 60-year-old woman presents to you with vision problems. Objects appear clear, but she just can't see as well as before. She says she first noticed this when she went to the movies with her grandkids, and she could not see the whole screen. She denies any complaints of redness, itchiness, or excessive tearing of her...
E: Brimonidine causes release of prostaglandins that relax the ciliary muscle and increases uveoscleral outflow.
Answer the following medical question with one of the provided options:
Q:A 62-year-old woman presents to the office because she has noticed yellowish bumps and patches on her elbows and knees that seem to come and go. Recently she noticed the same yellow bumps on her eyelids. She is a new patient and reports that she is otherwise healthy but did not have insurance until recently so she ha...
D: Lipid panel
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Q:A previously healthy 47-year-old woman comes to the emergency department because of a 2-week history of fatigue, abdominal distention, and vomiting. She drinks 6 beers daily. Physical examination shows pallor and scleral icterus. A fluid wave and shifting dullness are present on abdominal examination. The intravascul...
A: Short gastric vein
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Q:One month after undergoing surgical spinal fusion because of a traumatic spinal cord injury, a 68-year-old man comes to the physician because of lower abdominal pain. He last voided yesterday. Physical examination shows a suprapubic mass and decreased sensation below the umbilicus. Urodynamic studies show simultaneou...
E: Prazosin
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Q:A 24-year-old African American male with sickle cell disease has been followed by a hematologist since infancy. Two years ago, he was started on hydroxyurea for frequent pain crises but has not achieved good control. The addition of a Gardos channel blocking agent is being considered. What is the mechanism of action ...
A: Prevents RBC dehydration by inhibiting K+ efflux
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Q:A previously healthy 5-year-old boy is brought to the physician by his parents because of a 2-day history of poor balance and difficulty walking. He has fallen multiple times and is unable to walk up the stairs unassisted. He has also had difficulty tying his shoes and dressing himself. His family adheres to a vegeta...
B: Varicella zoster infection
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Q:A 58-year-old female presents to her primary care physician with a 1-month history of facial and chest flushing, as well as intermittent diarrhea and occasional difficulty breathing. On physical exam, a new-onset systolic ejection murmur is auscultated and is loudest at the left second intercostal space. Subsequent e...
E: Elevated urinary 5-hydroxyindoleacetic acid
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Q:A 53-year-old man is brought to the clinic by his son for the evaluation of unusual behavior. He is a shopkeeper by profession and sometimes behaves very rudely to the customers. Recently, he accused one of the customers of using black magic over his shop. He has been increasingly irritable, forgetting things, and ha...
E: Pick’s disease
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Q:A 32-year-old G0P0 African American woman presents to the physician with complaints of heavy menstrual bleeding as well as menstrual bleeding in between her periods. She also reports feeling fatigued and having bizarre cravings for ice and chalk. Despite heavy bleeding, she does not report any pain with menstruation....
E: Whorled pattern of smooth muscle bundles with well-defined borders
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Q:A young immigrant girl presents with low-grade fever, sore throat, painful swallowing, and difficulty in breathing. Her voice is unusually nasal and her swollen neck gives the impression of “bull's neck”. On examination, a large gray membrane is noticed on the oropharynx as shown in the picture. Removal of the membra...
D: ADP ribosylates EF-2 and prevents protein synthesis (ADP = adenosine diphosphate; EF-2 = elongation factor-2)
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Q:A 68-year-old man is brought to the emergency department by ambulance after he was found to be altered at home. Specifically, his wife says that he fell and was unable to get back up while walking to bed. When she approached him, she found that he was unable to move his left leg. His past medical history is significa...
A: Cingulate gyrus
Answer the following medical question with one of the provided options:
Q:A 9-year-old boy is brought to the emergency room by his mother for weakness, diaphoresis, and syncope. His mother says that he has never been diagnosed with any medical conditions but has been having “fainting spells” over the past month. Routine lab work reveals a glucose level of 25 mg/dL. The patient is promptly ...
B: Munchausen syndrome by proxy
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Q:A 35-year-old woman comes to the physician because of progressive left flank pain and increased urinary frequency for the past two weeks. Her appetite is normal and she has not had any nausea or vomiting. She has a history of type 1 diabetes mellitus that is poorly controlled with insulin. She is sexually active with...
D: Psoas muscle abscess
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Q:A 27-year-old woman, gravida 3, para 2, delivers twins via an uncomplicated vaginal delivery. Both placentas are delivered shortly afterward. The patient received regular prenatal care and experienced no issues during her pregnancy. Over the next hour, she continues to experience vaginal bleeding, with an estimated b...
E: Bimanual uterine massage
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Q:An otherwise healthy 78-year-old man is brought to the emergency department by his daughter because of a 1-day history of a diffuse headache and an inability to understand speech. There is no history of head trauma. He drinks one to two beers daily and occasionally more on weekends. His vital signs are within normal ...
E: Amyloid angiopathy
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Q:A 40-year-old woman presents to her primary care physician complaining of a several-month history of episodic sweating and heart racing. Her husband noticed that she becomes pale during these episodes. She also has progressive episodic pounding headaches which are not relieved by paracetamol. Her family history is ne...
D: Adrenal chromaffin cells
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Q:A 13-year-old boy is brought to the physician because of swelling around his eyes for the past 2 days. His mother also notes that his urine became gradually darker during this time. Three weeks ago, he was treated for bacterial tonsillitis. His temperature is 37.6°C (99.7°F), pulse is 79/min, and blood pressure is 15...
E: Granular deposits of IgG, IgM, and C3 on immunofluorescence
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Q:A 71 year-old female is brought to the emergency room by her husband. The husband reports that they were taking a walk together one hour ago, when his wife experienced sudden, right arm and leg weakness. He noticed that she had slurred speech, and that she was not able to tell him where she was. The patient underwent...
E: Atrial fibrillation
Answer the following medical question with one of the provided options:
Q:A 23-year-old man presents with increasing neck pain for several months that does not improve with nonsteroidal anti-inflammatory drugs. The patient says he has had neck pain ever since he was involved in a motor vehicle accident 10 months ago. For the last 2 weeks, he says he has also noticed weakness and numbness i...
D: A cavitation in the cervical spinal cord
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Q:A 45-year-old man presents to the emergency department because of fever and scrotal pain for 2 days. Medical history includes diabetes mellitus and morbid obesity. His temperature is 40.0°C (104.0°F), the pulse is 130/min, the respirations are 35/min, and the blood pressure is 90/68 mm Hg. Physical examination shows ...
E: Obtain an immediate portable chest radiograph to evaluate line placement
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Q:A 32-year-old man of Asian descent presents with a skin rash after being started on prophylactic doses of trimethoprim/sulfamethoxazole 3 weeks earlier. He was diagnosed with acquired immunodeficiency syndrome (AIDS) 2 months ago which prompted the initiation of prophylactic antibiotics. The vital signs include: bloo...
C: Stevens-Johnson syndrome
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Q:A 43-year-old woman comes to the physician because of a 2-month history of chest pain. She describes the pain as intermittent and burning-like. She states that she has tried using proton pump inhibitors but has had no relief of her symptoms. She has had a 5-kg (11-lb) weight loss over the past 2 months. Her temperatu...
B: Anti-topoisomerase antibodies
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Q:A 27-year-old man presents to the emergency department with general weakness and fatigue. He states that he has not felt well for several days and can't take care of himself anymore due to fatigue. The patient has a past medical history of IV drug abuse, alcohol abuse, and multiple minor traumas associated with intox...
C: Pseudomembranes of fibrin
Answer the following medical question with one of the provided options:
Q:A 9-year-old boy is brought to the physician for evaluation of a 3-day history of fever, sore throat, and itchy, red eyes. His symptoms began while he was away at summer camp. His immunizations are not up-to-date. He appears ill. His temperature is 39.1°C (102.3°F). Physical examination shows erythema and edema of th...
A: Adenovirus
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Q:A 70-year-old man presents to the emergency department with severe substernal chest pain of one hour’s duration. The patient was taking a morning walk when the onset of pain led him to seek care. His past medical history includes coronary artery disease, hyperlipidemia, and hypertension. Medications include aspirin, ...
C: Lateral wall of left ventricle, left circumflex coronary artery
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Q:A 68-year-old male visits his primary care physician after an episode of syncope during a tennis match. He reports exertional dyspnea with mild substernal chest pain. On physical exam a systolic crescendo-decrescendo murmur is heard best at the right 2nd intercostal space. This murmur was not heard at the patient's l...
B: Murmur radiates to carotid arteries bilaterally
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Q:A 37-year-old man presents to the physician. He has been overweight since childhood. He has not succeeded in losing weight despite following different diet and exercise programs over the past several years. He has had diabetes mellitus for 2 years and severe gastroesophageal reflux disease for 9 years. His medication...
C: Laparoscopic Roux-en-Y gastric bypass
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Q:An 8-year-old girl is brought to the emergency department because of a 2-day history of an intermittent, diffuse abdominal pain. She has also had a nonpruritic rash on her legs and swelling of her ankles for 1 week. Two weeks ago, she had a sore throat, which was treated with oral amoxicillin. Examination of the lowe...
E: Leukocytoclastic vasculitis
Answer the following medical question with one of the provided options:
Q:A 31-year-old physician notices that her senior colleague has been arriving late for work for the past 2 weeks. The colleague recently lost his wife to cancer and has been taking care of his four young children. Following the death of his wife, the department chair offered him extended time off but he declined. There...
C: Inform the local Physician Health Program
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Q:A 58-year-old man presents for a follow-up appointment. He recently was found to have a history of stage 2 chronic kidney disease secondary to benign prostatic hyperplasia leading to urinary tract obstruction. He has no other medical conditions. His father died at age 86 from a stroke, and his mother lives in an assi...
B: Enalapril
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Q:A 25-year-old man comes to the physician because he and his wife have been unable to conceive despite regular unprotected sex for the past 15 months without using contraception. His wife has been tested and is fertile. The patient began puberty at the age of 14 years. He was treated for Chlamydia trachomatis 6 years ...
C: Anabolic steroid use
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Q:A 48-year-old male with a history of rhinitis presents to the emergency department with complaints of shortness of breath and wheezing over the past 2 days. He reports bilateral knee pain over the past month for which he recently began taking naproxen 1 week ago. Physical examination is significant for a nasal polyp ...
C: Asthma
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Q:A 58-year-old lifeguard develops squamous cell carcinoma of the skin on his forehead. Which of the following most likely preceded the development of this carcinoma?? {'A': 'Hamartomatous lesion of sebaceous glands', 'B': 'Dry, scaly, hyperkeratotic papule', 'C': 'A single, large pink patch', 'D': 'Dermatophyte infect...
B: Dry, scaly, hyperkeratotic papule
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Q:A 29-year-old man is brought to the emergency department by his wife due to unusual behavior for the past week. She has noted several incidents when he spoke to her so fast that she could not understand what he was saying. She also says that one evening, he drove home naked after a night where he said he was ‘paintin...
D: Bipolar disorder, type I
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Q:A 65-year-old man presents with a small painless ulcer with a raised border on his right forearm which has persisted for the last 3 weeks. His past history is significant for 3 occurrences of basal cell carcinoma on different areas of the body during the last 4 years, which have all been surgically excised. The morph...
C: Inhibition of thymidylate synthase
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Q:A 29-year-old woman presents for a follow-up visit after an emergency appendectomy. The laparoscopic procedure went well with no complications. Physical examination reveals the surgical site is slightly tender but is healing appropriately. She is delighted that the operation went well and offers you a cake and VIP ti...
D: "Thank you, but I cannot accept the tickets you offered. Accepting such a generous gift is against our policy. However, I will gladly accept your cake and distribute it among the staff."
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Q:A 62-year-old man presents to the emergency department with increased fatigue and changes in his vision. The patient states that for the past month he has felt abnormally tired, and today he noticed his vision was blurry. The patient also endorses increased sweating at night and new onset headaches. He states that he...
C: IgM
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Q:A 42-year-old man presents to his primary care provider for a follow-up appointment after a new diagnosis of hypertension follow-up. The doctor mentions that a recent study where the effect of a healthy lifestyle education program on blood pressure was studied in 2 matched rural communities. One community received he...
D: Community trial
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Q:A 50-year-old female radiologist who is interviewing for a night shift position states that she was fired from her past 3 previous positions because she had difficulty working with others. She states that she is perfect for this job however, as she likes to work on her own and be left alone. She emphasizes that she d...
B: Schizoid
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Q:A 67-year-old female presents to her primary care physician complaining of headaches in her left temple and scalp area, neck stiffness, occasional blurred vision, and pain in her jaw when chewing. The appropriate medical therapy is initiated, and a subsequent biopsy of the temporal artery reveals arteritis. Five mont...
C: Drug-induced myopathy
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Q:A 67-year-old man presents to the office complaining of abdominal pain. He was started on a trial of proton pump inhibitors 5 weeks ago but the pain has not improved. He describes the pain as dull, cramping, and worse during meals. Medical history is unremarkable. Physical examination is normal except for tenderness ...
D: Left gastro-omental artery
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Q:A mother brings her 2-year-old son to the pediatrician following an episode of abdominal pain and bloody stool. The child has otherwise been healthy and growing normally. On physical exam, the patient is irritable with guarding of the right lower quadrant of the abdomen. Based on clinical suspicion, pertechnetate sci...
C: Vitelline duct
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Q:A 59-year-old patient comes to the emergency department accompanied by his wife because of severe right leg pain and numbness. His condition suddenly started an hour ago. His wife says that he has a heart rhythm problem for which he takes a blood thinner, but he is not compliant with his medications. He has smoked 10...
C: Urgent assessment for amputation or revascularization
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Q:A 12-year-old girl is brought to the pediatrician by her father who is concerned about the child’s ability to sit in a moving vehicle. She frequently develops nausea and dizziness when riding in a car for more than 10 minutes. The child has vomited twice over the past month while riding in the car. Her symptoms are s...
D: Muscarinic acetylcholine receptor antagonist
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Q:A 28-year-old female suffering from a urinary tract infection is given trimethoprim-sulfamethoxazole (TMP-SMX) by her physician. Several days later, she begins to experience itchiness and joint pain. Laboratory and histologic analysis reveals vasculitis and antibody complexes deposited near the basement membrane of t...
E: Lowered serum levels of complement protein C3
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Q:A 27-year-old woman presents to your office complaining of difficulty swallowing, and she describes that "there is something in the back of her throat". Furthermore, she also feels an "achy" chest pain that has been getting progressively worse over the last few weeks. She denies having any fever, shortness of breath,...
A: Benign tumor of the thymus
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Q:A 34-year-old woman comes to the physician for a follow-up appointment because of a blood pressure of 148/98 mm Hg at her last health maintenance examination four weeks ago. She feels well. She has a 20-year history of migraine with aura of moderate to severe intensity. For the past year, the headaches have been occu...
C: Propranolol
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Q:A mother brings her 25-month-old son to the pediatrician’s office for a well child visit. She reports he had an ear infection 3 months ago for which he took a short course of antibiotics but has otherwise been well. He is now in daycare where he likes to play with the other children. She says he can stack multiple cu...
E: None
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Q:A 68-year-old man is brought to the emergency department 25 minutes after he was found shaking violently on the bathroom floor. His wife reports that he has become increasingly confused over the past 2 days and that he has been sleeping more than usual. He was started on chemotherapy 4 months ago for chronic lymphocy...
E: Monoclonal antibody against CD20+
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Q:A 29-year-old woman presents to her primary care provider complaining of lower back pain. She reports a 3 day history of extreme right lower back pain. She also reports mild dysuria. Her past medical history is notable for recurrent urinary tract infections leading to 3 emergency room visits over the past year. Her f...
D: Proteus mirabilis
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Q:An 8-month-old boy is brought to the emergency room by his mother who notes that the child has not been passing stool regularly. Palpation and radiographic imaging of the umbilical region reveal the presence of fecal material in an abnormal out-pocketing of bowel. Which of the following is a common complication seen ...
C: Ulceration
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Q:A 69-year-old woman is brought to the clinic for difficulty breathing over the past 2 months. She denies any clear precipitating factor but reports that her breathing has become progressively labored and she feels like she can’t breathe. Her past medical history is significant for heart failure, diabetes mellitus, an...
E: Spironolactone
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Q:An 80-year-old woman presents with general malaise and low-grade fever. Physical examination reveals several retinal hemorrhages with pale centers, erythematous nodules on palms that are not painful, and splinter hemorrhages under her fingernails. Echocardiogram shows vegetations on the mitral valve. Blood culture in...
E: Colon cancer
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Q:A 63-year-old man presents to the physician with fever for 5 days. He has had increasing fatigue and dyspnea for the past 2 months. During this time, he has lost 3 kg (6.6 lb). He received outpatient treatment for pneumonia last month. He had urinary tract infection 2 weeks ago. He takes no other medications other th...
A: Acute myeloblastic leukemia
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Q:A 9-year-old girl is brought to her pediatrician by her mother for the evaluation of recent-onset seizures. She has had 2 episodes of generalized tonic-clonic seizures in the past 3 days. Each episode lasted for 1–2 minutes and aborted spontaneously. There is no history of fever, headache, altered behavior, diarrhea,...
D: Von Recklinghausen disease
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Q:A 7-year-old boy is brought to the emergency department by his parents. They state that he has had trouble walking the past day and this morning refuses to walk at all. The child has a past medical history of asthma, which is treated with albuterol. His temperature is 102°F (38.9°C), blood pressure is 77/48 mmHg, pul...
D: Staphylococcus aureus
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Q:A 24-year-old man presents to his family practitioner for routine follow-up of asthma. He is currently on albuterol, corticosteroids, and salmeterol, all via inhalation. The patient is compliant with his medications, but he still complains of episodic shortness of breath and wheezing. The peak expiratory flow (PEF) h...
D: Montelukast blocks receptors of some arachidonic acid metabolites.
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Q:A 25-year-old medical student is doing an international health elective in the Amazon River basin studying tropical disease epidemiology. As part of his pre-trip preparation, he wants to be protected from malaria and is researching options for prophylaxis. Which of the following agents should be avoided for malarial ...
A: Chloroquine
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Q:A 32-year-old woman presents complaining of nightmares. She reports that these “nightmares” happen when she is asleep and also sometimes when she is awake, but she cannot come up with another description for them. The episodes have been happening for at least 3 weeks now. She states that when it happens she feels “ou...
C: Depersonalization disorder
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Q:A 38-year-old woman comes to the physician for a 6-week history of sleeping difficulties because she thinks that someone is watching her through security cameras. Her anxiety started 6 weeks ago when a security camera was installed outside her house by the police. Ever since, she has felt that she is being monitored ...
B: Delusions
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Q:A 49-year-old man with alcohol use disorder is brought to the emergency department immediately after two episodes of coffee-ground emesis. His pulse is 116/min and blood pressure is 92/54 mm Hg. Physical examination shows a distended abdomen with shifting dullness. Skin examination shows jaundice, erythematous palms,...
D: D cells
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Q:A 19-year-old college student is brought to the emergency department by his roommates after being found unconscious on their dorm room floor. His temperature is 102.0°F (38.9°C) and blood pressure is 85/64 mmHg. On physical examination, he has multiple rose-colored spots on the skin covering his abdomen and lower lim...
E: Waterhouse-Friderichsen syndrome
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Q:A 39-year-old man with a history of major depression is brought into the emergency department by his concerned daughter. She reports that he was recently let go from work because of his sudden and erratic behavior at work. He was noted to be making inappropriate sexual advances to his female co-workers which is very ...
A: Mood stabilizers, antipsychotics, benzodiazepines, ECT
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Q:A 24-year-old woman, gravida 2, para 1, at 33 weeks’ gestation, is admitted to the hospital for treatment of preterm labor. She has no history of serious illness and her only medication is a multivitamin. Her temperature is 37.2°C (99.0°F), pulse is 100/min, respirations are 20/min, and blood pressure is 100/75 mm Hg...
A: Serum electrolytes
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Q:A 70-year-old male patient comes into your office because of leg pain. The patient states that his calves have been hurting more and more over the last two months. The pain isn't present at rest, but the pain develops as the patient starts walking and exerting himself. He states that stopping to rest is the only thin...
A: Lifestyle modifications
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Q:A 23-year-old man comes to the physician because of a 1-week history of muscle ache, fatigue, and fever that occurs every 2 days. He recently returned from a trip to Myanmar. A peripheral blood smear shows erythrocytes with brick-red granules. The physician recommends a combination of two antimicrobial drugs after co...
A: Prevention of infection relapse
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Q:A 20-year-old woman is brought to the emergency department by her parents after finding her seizing in her room at home. She has no known medical condition and this is her first witnessed seizure. She is stabilized in the emergency department. A detailed history reveals that the patient has been progressively calorie...
A: Hypophosphatemia
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Q:A 27-year-old woman, gravida 3, para 1, at 22 weeks gestation visits her physician for a prenatal visit. She feels well. Her current pregnancy has been uncomplicated. She has attended many prenatal appointments and followed the physician's advice about screening for diseases, laboratory testing, diet, and exercise. T...
A: Cerclage
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Q:A 23-year-old female presents to the emergency department complaining of a worsening headache. The patient reports that the headache started one month ago. It is constant and “all over” but gets worse when she is lying down or in the setting of bright lights. Review of systems is significant for low-grade fever, nigh...
B: Administer amphotericin B and 5-flucytosine
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Q:A 67-year-old man is brought to the emergency department by his wife due to dizziness, trouble with walking, and progressively worsening headache. These symptoms began approximately two hours prior to arriving to the hospital and were associated with nausea and one episode of vomiting. Medical history is significant ...
C: Dentate and interposed nuclei
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Q:A 52-year-old woman presents with fatigue and pain of the proximal interphalangeal and metacarpophalangeal joints for the past 6 months. She also has knee and wrist pain that has been present for the past 2 months, with morning stiffness that improves over the course of the day. Physical examination is significant fo...
A: HLA-DR4
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Q:A 27-year-old woman presents to the emergency department for sudden, bilateral, painful loss of vision. She states that her symptoms started last night and have persisted until this morning. The patient has a past medical history of peripheral neuropathy which is currently treated with duloxetine and severe anxiety. ...
C: A lumbar puncture demonstrating oligoclonal bands
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Q:A 36-year-old woman is fasting prior to a religious ceremony. Her only oral intake in the last 36 hours has been small amounts of water. The metabolic enzyme that is primarily responsible for maintaining normal blood glucose in this patient is located exclusively within the mitochondria. An increase in which of the f...
E: Acetyl coenzyme A
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Q:An 8-year-old boy is brought to the emergency department 3 hours after being bitten by his neighbor's dog. He was chasing the dog with a stick when it attacked him. He has fed the dog on multiple occasions and it has never bitten him before. His father saw the dog 2 hours after the incident and its behavior seemed no...
A: Observe the dog for 10 days